Rank | Gene Set | Z-score |
---|---|---|
1 | polyketide metabolic process (GO:0030638) | 6.45096077 |
2 | doxorubicin metabolic process (GO:0044598) | 6.45096077 |
3 | daunorubicin metabolic process (GO:0044597) | 6.45096077 |
4 | positive regulation of cellular amide metabolic process (GO:0034250) | 4.40942912 |
5 | superoxide anion generation (GO:0042554) | 4.34327479 |
6 | negative regulation of mast cell activation (GO:0033004) | 4.23034273 |
7 | detection of molecule of bacterial origin (GO:0032490) | 4.19514432 |
8 | regulation of activation of Janus kinase activity (GO:0010533) | 3.90817858 |
9 | aminoglycoside antibiotic metabolic process (GO:0030647) | 3.79261634 |
10 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.66832925 |
11 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.66832925 |
12 | DNA strand renaturation (GO:0000733) | 3.64237330 |
13 | response to pheromone (GO:0019236) | 3.56146911 |
14 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.45131046 |
15 | behavioral response to nicotine (GO:0035095) | 3.40225868 |
16 | detection of external biotic stimulus (GO:0098581) | 3.26524851 |
17 | histamine secretion (GO:0001821) | 3.20631887 |
18 | energy homeostasis (GO:0097009) | 3.14649363 |
19 | detection of other organism (GO:0098543) | 3.10561019 |
20 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.10129578 |
21 | detection of bacterium (GO:0016045) | 3.00367807 |
22 | positive regulation of heat generation (GO:0031652) | 2.97601480 |
23 | cellular response to exogenous dsRNA (GO:0071360) | 2.93284180 |
24 | detection of biotic stimulus (GO:0009595) | 2.90375522 |
25 | natural killer cell activation involved in immune response (GO:0002323) | 2.84094182 |
26 | nucleotide transmembrane transport (GO:1901679) | 2.83957482 |
27 | response to host immune response (GO:0052572) | 2.82946590 |
28 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.82946590 |
29 | ganglion development (GO:0061548) | 2.80420103 |
30 | cellular anion homeostasis (GO:0030002) | 2.79253137 |
31 | adenosine metabolic process (GO:0046085) | 2.77851393 |
32 | positive regulation of protein sumoylation (GO:0033235) | 2.75356153 |
33 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.74167795 |
34 | auditory receptor cell stereocilium organization (GO:0060088) | 2.68576391 |
35 | response to peptidoglycan (GO:0032494) | 2.67886107 |
36 | extracellular regulation of signal transduction (GO:1900115) | 2.67731685 |
37 | extracellular negative regulation of signal transduction (GO:1900116) | 2.67731685 |
38 | histamine transport (GO:0051608) | 2.66953797 |
39 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.65828421 |
40 | startle response (GO:0001964) | 2.65823941 |
41 | dentate gyrus development (GO:0021542) | 2.65097646 |
42 | dendritic cell chemotaxis (GO:0002407) | 2.63874480 |
43 | superoxide metabolic process (GO:0006801) | 2.63571462 |
44 | inner ear receptor stereocilium organization (GO:0060122) | 2.63283005 |
45 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.61395699 |
46 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.61395699 |
47 | modulation by symbiont of host immune response (GO:0052553) | 2.61395699 |
48 | positive regulation by symbiont of host defense response (GO:0052509) | 2.61395699 |
49 | modulation by symbiont of host defense response (GO:0052031) | 2.61395699 |
50 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.61395699 |
51 | positive regulation of antigen processing and presentation (GO:0002579) | 2.58885163 |
52 | interferon-gamma production (GO:0032609) | 2.57672530 |
53 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.57319311 |
54 | regulation of fever generation (GO:0031620) | 2.57237483 |
55 | dendritic cell migration (GO:0036336) | 2.55078085 |
56 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.52595460 |
57 | regulation of interleukin-8 secretion (GO:2000482) | 2.51509509 |
58 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.47936342 |
59 | cytochrome complex assembly (GO:0017004) | 2.45660004 |
60 | mannosylation (GO:0097502) | 2.44911362 |
61 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.39955003 |
62 | tRNA methylation (GO:0030488) | 2.38062974 |
63 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.38001497 |
64 | G-protein coupled receptor internalization (GO:0002031) | 2.36095510 |
65 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 2.35452057 |
66 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 2.35452057 |
67 | prostate gland growth (GO:0060736) | 2.35198487 |
68 | cell differentiation involved in metanephros development (GO:0072202) | 2.35077069 |
69 | protein heterotetramerization (GO:0051290) | 2.34932981 |
70 | positive regulation of interleukin-17 production (GO:0032740) | 2.34467409 |
71 | drinking behavior (GO:0042756) | 2.34439404 |
72 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.34364816 |
73 | eosinophil chemotaxis (GO:0048245) | 2.34124873 |
74 | developmental pigmentation (GO:0048066) | 2.32981657 |
75 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.30410175 |
76 | estrogen biosynthetic process (GO:0006703) | 2.29819303 |
77 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.29364124 |
78 | regulation of cellular extravasation (GO:0002691) | 2.29324914 |
79 | positive regulation of defense response to virus by host (GO:0002230) | 2.28558621 |
80 | mesenchymal cell differentiation (GO:0048762) | 2.28209207 |
81 | positive regulation of type 2 immune response (GO:0002830) | 2.27846036 |
82 | response to host (GO:0075136) | 2.27763051 |
83 | response to host defenses (GO:0052200) | 2.27763051 |
84 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.27763051 |
85 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 2.27340388 |
86 | positive regulation of T cell migration (GO:2000406) | 2.26929417 |
87 | macrophage activation (GO:0042116) | 2.26865326 |
88 | regulation of timing of cell differentiation (GO:0048505) | 2.25697196 |
89 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.25060774 |
90 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.25051731 |
91 | postsynaptic membrane organization (GO:0001941) | 2.24507200 |
92 | regulation of antigen processing and presentation (GO:0002577) | 2.24412822 |
93 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.23098445 |
94 | lipoxygenase pathway (GO:0019372) | 2.22670446 |
95 | negative regulation of meiosis (GO:0045835) | 2.22219906 |
96 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.21276864 |
97 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.21276864 |
98 | I-kappaB kinase/NF-kappaB signaling (GO:0007249) | 2.21264642 |
99 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.21205734 |
100 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 2.20242427 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.09844185 |
2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.96354719 |
3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.80389455 |
4 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.79688378 |
5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.63409037 |
6 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.54999900 |
7 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.52768398 |
8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.31127262 |
9 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.08363450 |
10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.06725593 |
11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.05903304 |
12 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.04165993 |
13 | P300_19829295_ChIP-Seq_ESCs_Human | 2.01963143 |
14 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.95629348 |
15 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.95104785 |
16 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.95038334 |
17 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.93009595 |
18 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.88084625 |
19 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.87974336 |
20 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.86189107 |
21 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.86142953 |
22 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.85400330 |
23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.81876757 |
24 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.81606727 |
25 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.80469935 |
26 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.76583049 |
27 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.76547279 |
28 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.76525592 |
29 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.75926422 |
30 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.74088781 |
31 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.73515427 |
32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.72787805 |
33 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.72390683 |
34 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.71241225 |
35 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.69240850 |
36 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.65897108 |
37 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.65000390 |
38 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.64952193 |
39 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.64932611 |
40 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.64872996 |
41 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.60231187 |
42 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.58963583 |
43 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.58963223 |
44 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57377952 |
45 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.56324093 |
46 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.53508249 |
47 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.52634844 |
48 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.50859926 |
49 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.49837729 |
50 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.49620695 |
51 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.49507547 |
52 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.49456256 |
53 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.48668791 |
54 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.47119262 |
55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.45430743 |
56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.44842615 |
57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.44393991 |
58 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.40660511 |
59 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.39261823 |
60 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36785051 |
61 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.35875518 |
62 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.34757112 |
63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34306197 |
64 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.33995700 |
65 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.33755208 |
66 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33755208 |
67 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.31676043 |
68 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29288382 |
69 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.28597949 |
70 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.26514079 |
71 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.25167098 |
72 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24758300 |
73 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.23608168 |
74 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.23186930 |
75 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.21921942 |
76 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.21648952 |
77 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.18821629 |
78 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.17563197 |
79 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.15568912 |
80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.15406864 |
81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13980354 |
82 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.13886672 |
83 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.13841232 |
84 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.13425861 |
85 | TCF4_23295773_ChIP-Seq_U87_Human | 1.12609920 |
86 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.12326354 |
87 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.12132306 |
88 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.12061543 |
89 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11471300 |
90 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.10664789 |
91 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.09896822 |
92 | VDR_22108803_ChIP-Seq_LS180_Human | 1.09456286 |
93 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.09125557 |
94 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.08332872 |
95 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.07393926 |
96 | KDM2B_26808549_Chip-Seq_REH_Human | 1.07184499 |
97 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.07040997 |
98 | STAT3_23295773_ChIP-Seq_U87_Human | 1.04442738 |
99 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.03617838 |
100 | JUN_21703547_ChIP-Seq_K562_Human | 1.02251957 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0006292_abnormal_olfactory_placode | 4.72608033 |
2 | MP0001188_hyperpigmentation | 3.70934446 |
3 | MP0000566_synostosis | 3.41312704 |
4 | MP0005645_abnormal_hypothalamus_physiol | 3.24049257 |
5 | MP0001986_abnormal_taste_sensitivity | 3.09020482 |
6 | MP0001835_abnormal_antigen_presentation | 2.67054060 |
7 | MP0002638_abnormal_pupillary_reflex | 2.61790790 |
8 | MP0002277_abnormal_respiratory_mucosa | 2.45666834 |
9 | MP0009697_abnormal_copulation | 2.43378505 |
10 | * MP0005646_abnormal_pituitary_gland | 2.42567067 |
11 | MP0002163_abnormal_gland_morphology | 2.28673716 |
12 | MP0010386_abnormal_urinary_bladder | 2.24973312 |
13 | MP0002876_abnormal_thyroid_physiology | 2.23018725 |
14 | MP0002148_abnormal_hypersensitivity_rea | 2.19526707 |
15 | MP0002132_abnormal_respiratory_system | 2.12759407 |
16 | MP0003787_abnormal_imprinting | 2.09366598 |
17 | MP0005171_absent_coat_pigmentation | 2.00458703 |
18 | MP0000015_abnormal_ear_pigmentation | 1.97823481 |
19 | MP0009785_altered_susceptibility_to | 1.95228560 |
20 | MP0000678_abnormal_parathyroid_gland | 1.92058909 |
21 | MP0001984_abnormal_olfaction | 1.90601701 |
22 | MP0005379_endocrine/exocrine_gland_phen | 1.73728937 |
23 | MP0003136_yellow_coat_color | 1.64580772 |
24 | MP0003183_abnormal_peptide_metabolism | 1.58983589 |
25 | MP0005671_abnormal_response_to | 1.58367572 |
26 | MP0000569_abnormal_digit_pigmentation | 1.58320688 |
27 | MP0002102_abnormal_ear_morphology | 1.52359626 |
28 | MP0000372_irregular_coat_pigmentation | 1.51724276 |
29 | MP0006276_abnormal_autonomic_nervous | 1.48152373 |
30 | MP0005075_abnormal_melanosome_morpholog | 1.44668003 |
31 | MP0001790_abnormal_immune_system | 1.42032218 |
32 | MP0005387_immune_system_phenotype | 1.42032218 |
33 | MP0005084_abnormal_gallbladder_morpholo | 1.39179882 |
34 | MP0002419_abnormal_innate_immunity | 1.38640358 |
35 | MP0003941_abnormal_skin_development | 1.36346965 |
36 | MP0000049_abnormal_middle_ear | 1.35755450 |
37 | MP0003122_maternal_imprinting | 1.34532251 |
38 | MP0008004_abnormal_stomach_pH | 1.29484844 |
39 | MP0005423_abnormal_somatic_nervous | 1.28489251 |
40 | MP0001529_abnormal_vocalization | 1.27242908 |
41 | MP0008058_abnormal_DNA_repair | 1.22133301 |
42 | MP0002938_white_spotting | 1.21229729 |
43 | MP0009764_decreased_sensitivity_to | 1.20948174 |
44 | MP0004742_abnormal_vestibular_system | 1.17969513 |
45 | MP0002452_abnormal_antigen_presenting | 1.15033965 |
46 | MP0005025_abnormal_response_to | 1.14792342 |
47 | MP0002735_abnormal_chemical_nociception | 1.13728823 |
48 | MP0003121_genomic_imprinting | 1.13128534 |
49 | MP0005000_abnormal_immune_tolerance | 1.12358217 |
50 | MP0002736_abnormal_nociception_after | 1.10691553 |
51 | * MP0000681_abnormal_thyroid_gland | 1.09754025 |
52 | MP0005310_abnormal_salivary_gland | 1.09221547 |
53 | MP0003436_decreased_susceptibility_to | 1.04790509 |
54 | MP0003943_abnormal_hepatobiliary_system | 1.03386931 |
55 | MP0004381_abnormal_hair_follicle | 1.02672850 |
56 | MP0001186_pigmentation_phenotype | 1.02519610 |
57 | MP0000026_abnormal_inner_ear | 1.02370254 |
58 | MP0005551_abnormal_eye_electrophysiolog | 1.00918524 |
59 | MP0008260_abnormal_autophagy | 0.99279701 |
60 | MP0005174_abnormal_tail_pigmentation | 0.99137965 |
61 | MP0001819_abnormal_immune_cell | 0.97971915 |
62 | MP0005503_abnormal_tendon_morphology | 0.97755921 |
63 | MP0001800_abnormal_humoral_immune | 0.97314762 |
64 | MP0002723_abnormal_immune_serum | 0.96498680 |
65 | MP0005253_abnormal_eye_physiology | 0.95986549 |
66 | MP0001502_abnormal_circadian_rhythm | 0.95661394 |
67 | MP0002420_abnormal_adaptive_immunity | 0.95303606 |
68 | MP0002095_abnormal_skin_pigmentation | 0.94710538 |
69 | MP0004147_increased_porphyrin_level | 0.94699127 |
70 | MP0003724_increased_susceptibility_to | 0.93925597 |
71 | MP0001486_abnormal_startle_reflex | 0.93191160 |
72 | MP0001764_abnormal_homeostasis | 0.89927533 |
73 | MP0003878_abnormal_ear_physiology | 0.89723866 |
74 | MP0005377_hearing/vestibular/ear_phenot | 0.89723866 |
75 | MP0002249_abnormal_larynx_morphology | 0.88274210 |
76 | MP0005248_abnormal_Harderian_gland | 0.88270933 |
77 | MP0005257_abnormal_intraocular_pressure | 0.88144897 |
78 | MP0001346_abnormal_lacrimal_gland | 0.86313290 |
79 | MP0002557_abnormal_social/conspecific_i | 0.83324165 |
80 | MP0003880_abnormal_central_pattern | 0.82924067 |
81 | * MP0001119_abnormal_female_reproductive | 0.81286875 |
82 | MP0002751_abnormal_autonomic_nervous | 0.80056518 |
83 | MP0003011_delayed_dark_adaptation | 0.79692790 |
84 | MP0008007_abnormal_cellular_replicative | 0.77094647 |
85 | MP0003938_abnormal_ear_development | 0.76194925 |
86 | MP0005451_abnormal_body_composition | 0.75717239 |
87 | MP0002098_abnormal_vibrissa_morphology | 0.75351446 |
88 | MP0009745_abnormal_behavioral_response | 0.74497320 |
89 | MP0002396_abnormal_hematopoietic_system | 0.73816387 |
90 | * MP0000631_abnormal_neuroendocrine_gland | 0.73682972 |
91 | MP0003763_abnormal_thymus_physiology | 0.72357640 |
92 | MP0002177_abnormal_outer_ear | 0.72083568 |
93 | MP0002572_abnormal_emotion/affect_behav | 0.71692403 |
94 | MP0002075_abnormal_coat/hair_pigmentati | 0.71553470 |
95 | MP0002127_abnormal_cardiovascular_syste | 0.70894162 |
96 | MP0001968_abnormal_touch/_nociception | 0.69576470 |
97 | MP0001270_distended_abdomen | 0.69207142 |
98 | MP0002998_abnormal_bone_remodeling | 0.68883317 |
99 | MP0001324_abnormal_eye_pigmentation | 0.68605605 |
100 | MP0001501_abnormal_sleep_pattern | 0.68343347 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.03123451 |
2 | Chromsome breakage (HP:0040012) | 4.35326632 |
3 | Abnormality of the renal collecting system (HP:0004742) | 3.57463918 |
4 | True hermaphroditism (HP:0010459) | 3.26711222 |
5 | Alveolar cell carcinoma (HP:0006519) | 3.08971002 |
6 | Duplicated collecting system (HP:0000081) | 3.08857642 |
7 | Optic neuritis (HP:0100653) | 3.05414972 |
8 | Retrobulbar optic neuritis (HP:0100654) | 3.05414972 |
9 | Congenital stationary night blindness (HP:0007642) | 2.98561395 |
10 | Osteomalacia (HP:0002749) | 2.95656516 |
11 | Thyroid-stimulating hormone excess (HP:0002925) | 2.88985635 |
12 | Abnormal hair whorl (HP:0010721) | 2.87021871 |
13 | Hypothermia (HP:0002045) | 2.83447735 |
14 | Ectopic kidney (HP:0000086) | 2.81356316 |
15 | Type I transferrin isoform profile (HP:0003642) | 2.79384215 |
16 | Febrile seizures (HP:0002373) | 2.77836733 |
17 | Chronic hepatic failure (HP:0100626) | 2.64920076 |
18 | Pancreatic fibrosis (HP:0100732) | 2.64398682 |
19 | Protruding tongue (HP:0010808) | 2.61639603 |
20 | Reduced antithrombin III activity (HP:0001976) | 2.60817418 |
21 | Absent eyebrow (HP:0002223) | 2.54072166 |
22 | Recurrent abscess formation (HP:0002722) | 2.50819633 |
23 | Clubbing of toes (HP:0100760) | 2.47854190 |
24 | Hypoplasia of the fovea (HP:0007750) | 2.46986517 |
25 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.46986517 |
26 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.45184224 |
27 | Decreased central vision (HP:0007663) | 2.42301920 |
28 | Congenital sensorineural hearing impairment (HP:0008527) | 2.42087402 |
29 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.39414435 |
30 | Orchitis (HP:0100796) | 2.35226010 |
31 | Nephrogenic diabetes insipidus (HP:0009806) | 2.34509576 |
32 | Pancreatic cysts (HP:0001737) | 2.30706035 |
33 | Abnormality of the preputium (HP:0100587) | 2.29497782 |
34 | Increased IgM level (HP:0003496) | 2.28812030 |
35 | Medial flaring of the eyebrow (HP:0010747) | 2.25010656 |
36 | Type 2 muscle fiber atrophy (HP:0003554) | 2.24449723 |
37 | Abnormality of incisor morphology (HP:0011063) | 2.24128192 |
38 | Prostate neoplasm (HP:0100787) | 2.23854746 |
39 | Meckel diverticulum (HP:0002245) | 2.20637504 |
40 | Abnormality of the ileum (HP:0001549) | 2.19647669 |
41 | Decreased circulating renin level (HP:0003351) | 2.17496175 |
42 | Mediastinal lymphadenopathy (HP:0100721) | 2.17464717 |
43 | Renal cortical cysts (HP:0000803) | 2.17077332 |
44 | Myositis (HP:0100614) | 2.08997945 |
45 | Fair hair (HP:0002286) | 2.04551384 |
46 | Recurrent bacterial skin infections (HP:0005406) | 2.03130518 |
47 | Abnormality of chromosome stability (HP:0003220) | 2.00572370 |
48 | Preaxial hand polydactyly (HP:0001177) | 2.00176881 |
49 | Pulmonary infiltrates (HP:0002113) | 1.96870487 |
50 | Abnormality of DNA repair (HP:0003254) | 1.95113507 |
51 | White forelock (HP:0002211) | 1.93958920 |
52 | Dry hair (HP:0011359) | 1.92669812 |
53 | Oligohydramnios (HP:0001562) | 1.91104729 |
54 | Congenital primary aphakia (HP:0007707) | 1.90721426 |
55 | Abnormality of the prostate (HP:0008775) | 1.90539107 |
56 | Abnormality of the renal cortex (HP:0011035) | 1.88744293 |
57 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.87777308 |
58 | Patchy hypopigmentation of hair (HP:0011365) | 1.87133496 |
59 | Abnormal biliary tract physiology (HP:0012439) | 1.86687903 |
60 | Bile duct proliferation (HP:0001408) | 1.86687903 |
61 | Absent/shortened dynein arms (HP:0200106) | 1.84977654 |
62 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.84977654 |
63 | Attenuation of retinal blood vessels (HP:0007843) | 1.84916632 |
64 | Duplication of thumb phalanx (HP:0009942) | 1.84880457 |
65 | Conjugated hyperbilirubinemia (HP:0002908) | 1.82197920 |
66 | Abnormality of the fovea (HP:0000493) | 1.80487486 |
67 | Congenital hepatic fibrosis (HP:0002612) | 1.80166531 |
68 | Postaxial foot polydactyly (HP:0001830) | 1.80140683 |
69 | Eczematoid dermatitis (HP:0000976) | 1.78097594 |
70 | Gait imbalance (HP:0002141) | 1.77617433 |
71 | Cheilitis (HP:0100825) | 1.75665482 |
72 | Tubulointerstitial nephritis (HP:0001970) | 1.74401138 |
73 | Optic nerve coloboma (HP:0000588) | 1.74041468 |
74 | Keratoconjunctivitis sicca (HP:0001097) | 1.73763995 |
75 | Muscle fiber atrophy (HP:0100295) | 1.73570781 |
76 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.73551409 |
77 | Tetany (HP:0001281) | 1.72940311 |
78 | Astigmatism (HP:0000483) | 1.72891088 |
79 | Abnormal protein glycosylation (HP:0012346) | 1.72394853 |
80 | Abnormal glycosylation (HP:0012345) | 1.72394853 |
81 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.72394853 |
82 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.72394853 |
83 | Renal dysplasia (HP:0000110) | 1.71657215 |
84 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.71508319 |
85 | Anomalous pulmonary venous return (HP:0010772) | 1.71037401 |
86 | Glomerulopathy (HP:0100820) | 1.70751242 |
87 | Abnormality of the nasal septum (HP:0000419) | 1.70515258 |
88 | Abnormal ciliary motility (HP:0012262) | 1.69418436 |
89 | Hypoplastic heart (HP:0001961) | 1.69327538 |
90 | Generalized hypopigmentation of hair (HP:0011358) | 1.68677655 |
91 | Abnormality of the renal medulla (HP:0100957) | 1.68314155 |
92 | Recurrent pneumonia (HP:0006532) | 1.68227598 |
93 | Conical tooth (HP:0000698) | 1.67066941 |
94 | Hypergonadotropic hypogonadism (HP:0000815) | 1.66957103 |
95 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.65387752 |
96 | Hyperphosphatemia (HP:0002905) | 1.64789894 |
97 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.64359970 |
98 | Keratoconjunctivitis (HP:0001096) | 1.64159972 |
99 | Pulmonary artery stenosis (HP:0004415) | 1.61901249 |
100 | Aplasia of the musculature (HP:0100854) | 1.61387703 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SIK3 | 4.88571824 |
2 | PRPF4B | 3.59154425 |
3 | CASK | 3.31718524 |
4 | MAP3K14 | 3.02707786 |
5 | TNIK | 2.97994196 |
6 | ZAK | 2.78927411 |
7 | IRAK3 | 2.70965372 |
8 | IRAK4 | 2.53453266 |
9 | TXK | 2.36884656 |
10 | INSRR | 2.03737824 |
11 | BMPR1B | 2.00993949 |
12 | SGK2 | 1.93246438 |
13 | ADRBK2 | 1.81382629 |
14 | STK38L | 1.81207666 |
15 | TAOK2 | 1.79324410 |
16 | AKT3 | 1.78702300 |
17 | STK24 | 1.58981994 |
18 | MAP2K7 | 1.57363604 |
19 | YES1 | 1.55471519 |
20 | NEK6 | 1.49283769 |
21 | ERBB3 | 1.48328737 |
22 | TEC | 1.48037658 |
23 | BMPR2 | 1.46590829 |
24 | CDK8 | 1.42698141 |
25 | EIF2AK2 | 1.42440998 |
26 | TIE1 | 1.31320229 |
27 | CCNB1 | 1.30072865 |
28 | BCR | 1.27953160 |
29 | MAPK13 | 1.25904474 |
30 | WNK3 | 1.21997115 |
31 | CLK1 | 1.19133008 |
32 | STK16 | 1.17996307 |
33 | SGK223 | 1.17838615 |
34 | SGK494 | 1.17838615 |
35 | NUAK1 | 1.11857854 |
36 | SRPK1 | 1.06893728 |
37 | CDK3 | 1.04665477 |
38 | MAP3K12 | 1.04561842 |
39 | SGK3 | 1.00441342 |
40 | IKBKB | 0.99221055 |
41 | JAK3 | 0.94720199 |
42 | NTRK3 | 0.92811163 |
43 | GRK1 | 0.91009601 |
44 | SIK2 | 0.87411550 |
45 | PBK | 0.86690535 |
46 | TRPM7 | 0.85497963 |
47 | CHUK | 0.83549811 |
48 | MUSK | 0.81068162 |
49 | NLK | 0.80594945 |
50 | VRK1 | 0.78479860 |
51 | ACVR1B | 0.76507122 |
52 | NEK9 | 0.75919426 |
53 | IKBKE | 0.75896266 |
54 | EPHB2 | 0.74394558 |
55 | OBSCN | 0.72435050 |
56 | BLK | 0.68617963 |
57 | MAPK7 | 0.67625732 |
58 | GRK7 | 0.67091594 |
59 | TAOK3 | 0.66000971 |
60 | BRAF | 0.65573278 |
61 | TSSK6 | 0.65304692 |
62 | PIM2 | 0.64937973 |
63 | PRKCE | 0.64632146 |
64 | MARK3 | 0.63562887 |
65 | EPHA3 | 0.63314802 |
66 | MKNK2 | 0.62934105 |
67 | PINK1 | 0.62405322 |
68 | MYLK | 0.60820917 |
69 | EIF2AK3 | 0.60800999 |
70 | EPHA4 | 0.59857421 |
71 | PLK2 | 0.58369205 |
72 | PASK | 0.57383904 |
73 | BTK | 0.57292896 |
74 | ATR | 0.55446354 |
75 | MKNK1 | 0.55109321 |
76 | IRAK1 | 0.54350186 |
77 | RPS6KB1 | 0.53456806 |
78 | SYK | 0.53037476 |
79 | LYN | 0.52936394 |
80 | IRAK2 | 0.52063436 |
81 | KIT | 0.49588260 |
82 | MAP2K6 | 0.48524951 |
83 | RPS6KA6 | 0.46843041 |
84 | TYK2 | 0.46533693 |
85 | RPS6KA2 | 0.45009384 |
86 | SIK1 | 0.44645369 |
87 | BRD4 | 0.42337199 |
88 | DYRK2 | 0.42106749 |
89 | TBK1 | 0.42029753 |
90 | RPS6KC1 | 0.40310658 |
91 | RPS6KL1 | 0.40310658 |
92 | PIK3CG | 0.38062258 |
93 | TNK2 | 0.37021928 |
94 | PRKCD | 0.33853393 |
95 | SGK1 | 0.32465533 |
96 | STK4 | 0.31453582 |
97 | PRKCG | 0.31113267 |
98 | DYRK1A | 0.29696724 |
99 | ADRBK1 | 0.28552751 |
100 | JAK1 | 0.28518100 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Allograft rejection_Homo sapiens_hsa05330 | 2.91076363 |
2 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.72862455 |
3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.44556257 |
4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.38090039 |
5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.32502091 |
6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.29321224 |
7 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.14237394 |
8 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.11374229 |
9 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.05639271 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.02938525 |
11 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.02809050 |
12 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.02563985 |
13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.01622648 |
14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.95438558 |
15 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.94466449 |
16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.92764670 |
17 | Base excision repair_Homo sapiens_hsa03410 | 1.90671787 |
18 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.80760881 |
19 | Phototransduction_Homo sapiens_hsa04744 | 1.79708811 |
20 | Measles_Homo sapiens_hsa05162 | 1.74576145 |
21 | Nicotine addiction_Homo sapiens_hsa05033 | 1.68439618 |
22 | Asthma_Homo sapiens_hsa05310 | 1.68121017 |
23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.59559164 |
24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.56985515 |
25 | Leishmaniasis_Homo sapiens_hsa05140 | 1.42431708 |
26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.37723710 |
27 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.32522191 |
28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.28954839 |
29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.28140632 |
30 | Influenza A_Homo sapiens_hsa05164 | 1.26421363 |
31 | Protein export_Homo sapiens_hsa03060 | 1.25783448 |
32 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.24992649 |
33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.21225348 |
34 | Taste transduction_Homo sapiens_hsa04742 | 1.20816600 |
35 | Phagosome_Homo sapiens_hsa04145 | 1.17955895 |
36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16674683 |
37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.16022177 |
38 | Legionellosis_Homo sapiens_hsa05134 | 1.11843748 |
39 | DNA replication_Homo sapiens_hsa03030 | 1.09244567 |
40 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.08517204 |
41 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.08169707 |
42 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.00294047 |
43 | Morphine addiction_Homo sapiens_hsa05032 | 0.98123967 |
44 | Olfactory transduction_Homo sapiens_hsa04740 | 0.94149909 |
45 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.94093651 |
46 | Pertussis_Homo sapiens_hsa05133 | 0.91908286 |
47 | Malaria_Homo sapiens_hsa05144 | 0.89972908 |
48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.88098176 |
49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.87335272 |
50 | Mismatch repair_Homo sapiens_hsa03430 | 0.86112034 |
51 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85899889 |
52 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.85159489 |
53 | Tuberculosis_Homo sapiens_hsa05152 | 0.80932547 |
54 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.80833164 |
55 | Purine metabolism_Homo sapiens_hsa00230 | 0.80617728 |
56 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.79203371 |
57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.76525963 |
58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74516153 |
59 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.74165421 |
60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73431418 |
61 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.73243817 |
62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.72032866 |
63 | RNA degradation_Homo sapiens_hsa03018 | 0.71089751 |
64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.69007293 |
65 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67377097 |
66 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.65468336 |
67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.65285559 |
68 | Other glycan degradation_Homo sapiens_hsa00511 | 0.65046147 |
69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63928867 |
70 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.63400652 |
71 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.62521658 |
72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.56863416 |
73 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.52386472 |
74 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51515189 |
75 | Circadian rhythm_Homo sapiens_hsa04710 | 0.50507474 |
76 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.50371345 |
77 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.50149191 |
78 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.49298386 |
79 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.44828586 |
80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44712120 |
81 | Hepatitis C_Homo sapiens_hsa05160 | 0.42441652 |
82 | Hepatitis B_Homo sapiens_hsa05161 | 0.42272596 |
83 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.42090960 |
84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38926811 |
85 | Apoptosis_Homo sapiens_hsa04210 | 0.38758068 |
86 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.38443508 |
87 | Mineral absorption_Homo sapiens_hsa04978 | 0.36674101 |
88 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.35438257 |
89 | Circadian entrainment_Homo sapiens_hsa04713 | 0.35197993 |
90 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.34531682 |
91 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.34208383 |
92 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.33379514 |
93 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.32295160 |
94 | HTLV-I infection_Homo sapiens_hsa05166 | 0.30704393 |
95 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.30465097 |
96 | Melanoma_Homo sapiens_hsa05218 | 0.30115064 |
97 | Shigellosis_Homo sapiens_hsa05131 | 0.29764597 |
98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29374287 |
99 | Salmonella infection_Homo sapiens_hsa05132 | 0.29223121 |
100 | Axon guidance_Homo sapiens_hsa04360 | 0.28042523 |