

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cysteine metabolic process (GO:0006534) | 5.73549499 |
| 2 | protein neddylation (GO:0045116) | 5.57942625 |
| 3 | negative regulation of cAMP-mediated signaling (GO:0043951) | 5.50498004 |
| 4 | artery smooth muscle contraction (GO:0014824) | 5.49890687 |
| 5 | leukotriene biosynthetic process (GO:0019370) | 5.06495772 |
| 6 | behavioral response to ethanol (GO:0048149) | 5.01743053 |
| 7 | tonic smooth muscle contraction (GO:0014820) | 4.99109876 |
| 8 | negative regulation of appetite (GO:0032099) | 4.88953761 |
| 9 | negative regulation of response to food (GO:0032096) | 4.88953761 |
| 10 | response to gravity (GO:0009629) | 4.87794044 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.81938515 |
| 12 | regulation of cilium movement (GO:0003352) | 4.69086751 |
| 13 | viral transcription (GO:0019083) | 4.61151620 |
| 14 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.55781037 |
| 15 | behavioral response to cocaine (GO:0048148) | 4.49088015 |
| 16 | translational termination (GO:0006415) | 4.43435822 |
| 17 | ATP synthesis coupled proton transport (GO:0015986) | 4.37875512 |
| 18 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.37875512 |
| 19 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 4.35978135 |
| 20 | opioid receptor signaling pathway (GO:0038003) | 4.33968231 |
| 21 | vascular smooth muscle contraction (GO:0014829) | 4.14500750 |
| 22 | serine family amino acid biosynthetic process (GO:0009070) | 4.13298836 |
| 23 | nonmotile primary cilium assembly (GO:0035058) | 4.05481827 |
| 24 | cotranslational protein targeting to membrane (GO:0006613) | 4.03065288 |
| 25 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.00763833 |
| 26 | regulation of appetite (GO:0032098) | 3.99988556 |
| 27 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.94539455 |
| 28 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.93340924 |
| 29 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.92058339 |
| 30 | UMP metabolic process (GO:0046049) | 3.92058339 |
| 31 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.92058339 |
| 32 | UMP biosynthetic process (GO:0006222) | 3.92058339 |
| 33 | protein targeting to ER (GO:0045047) | 3.91414642 |
| 34 | protein localization to endoplasmic reticulum (GO:0070972) | 3.82285606 |
| 35 | termination of RNA polymerase III transcription (GO:0006386) | 3.78004078 |
| 36 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.78004078 |
| 37 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.76690237 |
| 38 | translational elongation (GO:0006414) | 3.75068664 |
| 39 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.71987462 |
| 40 | nucleotide transmembrane transport (GO:1901679) | 3.64429634 |
| 41 | striatum development (GO:0021756) | 3.63804619 |
| 42 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.62826883 |
| 43 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.62324197 |
| 44 | cellular response to leptin stimulus (GO:0044320) | 3.60972771 |
| 45 | negative regulation of amino acid transport (GO:0051956) | 3.56095893 |
| 46 | ribosomal large subunit biogenesis (GO:0042273) | 3.52484784 |
| 47 | cardiac left ventricle morphogenesis (GO:0003214) | 3.48773377 |
| 48 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.44829617 |
| 49 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.40618220 |
| 50 | fatty acid derivative biosynthetic process (GO:1901570) | 3.39259037 |
| 51 | icosanoid biosynthetic process (GO:0046456) | 3.39259037 |
| 52 | leukotriene metabolic process (GO:0006691) | 3.37496504 |
| 53 | somite rostral/caudal axis specification (GO:0032525) | 3.36251413 |
| 54 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.36041321 |
| 55 | protein complex biogenesis (GO:0070271) | 3.35880601 |
| 56 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 3.23564729 |
| 57 | regulation of response to food (GO:0032095) | 3.23465799 |
| 58 | SMAD protein complex assembly (GO:0007183) | 3.22844687 |
| 59 | cellular protein complex disassembly (GO:0043624) | 3.22759769 |
| 60 | ether lipid metabolic process (GO:0046485) | 3.21016087 |
| 61 | sequestering of actin monomers (GO:0042989) | 3.20851355 |
| 62 | pyrimidine nucleoside biosynthetic process (GO:0046134) | 3.20153985 |
| 63 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.18881401 |
| 64 | protein localization to synapse (GO:0035418) | 3.18550606 |
| 65 | transmission of nerve impulse (GO:0019226) | 3.11496020 |
| 66 | melanosome transport (GO:0032402) | 3.11459315 |
| 67 | brain morphogenesis (GO:0048854) | 3.08002208 |
| 68 | prenylation (GO:0097354) | 3.07758667 |
| 69 | protein prenylation (GO:0018342) | 3.07758667 |
| 70 | sensory perception of smell (GO:0007608) | 3.07726401 |
| 71 | viral life cycle (GO:0019058) | 3.06367845 |
| 72 | regulation of endothelial cell differentiation (GO:0045601) | 3.06164400 |
| 73 | sulfur amino acid biosynthetic process (GO:0000097) | 3.02451548 |
| 74 | establishment of melanosome localization (GO:0032401) | 3.00614802 |
| 75 | regulation of glutamate secretion (GO:0014048) | 2.94674318 |
| 76 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.94104149 |
| 77 | negative regulation of membrane potential (GO:0045837) | 2.93920262 |
| 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.93172919 |
| 79 | skeletal muscle tissue regeneration (GO:0043403) | 2.92707448 |
| 80 | melanosome localization (GO:0032400) | 2.91278418 |
| 81 | pyrimidine-containing compound biosynthetic process (GO:0072528) | 2.90826353 |
| 82 | pigment granule transport (GO:0051904) | 2.89862009 |
| 83 | regulation of chromatin binding (GO:0035561) | 2.89390979 |
| 84 | response to leptin (GO:0044321) | 2.87409856 |
| 85 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.84335782 |
| 86 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.82959863 |
| 87 | protein localization to cilium (GO:0061512) | 2.81230930 |
| 88 | establishment of pigment granule localization (GO:0051905) | 2.80428011 |
| 89 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.80053246 |
| 90 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.79747988 |
| 91 | NADH dehydrogenase complex assembly (GO:0010257) | 2.78949505 |
| 92 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.78949505 |
| 93 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.78949505 |
| 94 | cellular glucuronidation (GO:0052695) | 2.78159065 |
| 95 | convergent extension (GO:0060026) | 2.73673958 |
| 96 | pigment granule localization (GO:0051875) | 2.73080025 |
| 97 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.72514082 |
| 98 | nucleoside transmembrane transport (GO:1901642) | 2.68339027 |
| 99 | protein targeting to membrane (GO:0006612) | 2.68192554 |
| 100 | regulation of skeletal muscle contraction (GO:0014819) | 2.67841958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 4.49070734 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.47746298 |
| 3 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.19593043 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.00210761 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.94338233 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.68885475 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.57092296 |
| 8 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.48125814 |
| 9 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.37633995 |
| 10 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.33523616 |
| 11 | FUS_26573619_Chip-Seq_HEK293_Human | 2.22297239 |
| 12 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.09811972 |
| 13 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.09264939 |
| 14 | P300_19829295_ChIP-Seq_ESCs_Human | 2.08261921 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.08090896 |
| 16 | EGR1_19032775_ChIP-ChIP_M12_Human | 2.07663197 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.03535457 |
| 18 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.02344828 |
| 19 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.00619876 |
| 20 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.98974421 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.97163297 |
| 22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.93905810 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.87237930 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86092276 |
| 25 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83925813 |
| 26 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.81898672 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77538954 |
| 28 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.76148940 |
| 29 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.68073811 |
| 30 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.67279169 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.65844849 |
| 32 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.65818683 |
| 33 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.65442596 |
| 34 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.63642979 |
| 35 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.58260255 |
| 36 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.57846417 |
| 37 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.57275224 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.55436938 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.52464942 |
| 40 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.49635560 |
| 41 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.47699045 |
| 42 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.45324559 |
| 43 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.44035483 |
| 44 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.44035483 |
| 45 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.44035483 |
| 46 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.42702287 |
| 47 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.42414417 |
| 48 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.38716077 |
| 49 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.38407646 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.36929235 |
| 51 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.36929235 |
| 52 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.36779425 |
| 53 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.36414543 |
| 54 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35957014 |
| 55 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.34254181 |
| 56 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.33751283 |
| 57 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.33174723 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30065091 |
| 59 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.28901788 |
| 60 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.28217812 |
| 61 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.28149056 |
| 62 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.28014397 |
| 63 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.24715761 |
| 64 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.23550819 |
| 65 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.23550819 |
| 66 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.22907103 |
| 67 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.22080615 |
| 68 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.21138958 |
| 69 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.19543572 |
| 70 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.18183862 |
| 71 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.17656486 |
| 72 | RXR_22108803_ChIP-Seq_LS180_Human | 1.17524910 |
| 73 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.16907209 |
| 74 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.16644503 |
| 75 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.15440595 |
| 76 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15390583 |
| 77 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15346490 |
| 78 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.15101666 |
| 79 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.14786569 |
| 80 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.13389075 |
| 81 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.13389075 |
| 82 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.09645269 |
| 83 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.08199550 |
| 84 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.08199550 |
| 85 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.08103917 |
| 86 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06780965 |
| 87 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.06098270 |
| 88 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.06008445 |
| 89 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.04108948 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.04076390 |
| 91 | TCF4_23295773_ChIP-Seq_U87_Human | 1.04046250 |
| 92 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.03286261 |
| 93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01274178 |
| 94 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01274178 |
| 95 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.01052471 |
| 96 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.99165969 |
| 97 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97833614 |
| 98 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97075374 |
| 99 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.96633216 |
| 100 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.95451200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005499_abnormal_olfactory_system | 5.02234898 |
| 2 | MP0005394_taste/olfaction_phenotype | 5.02234898 |
| 3 | MP0008789_abnormal_olfactory_epithelium | 4.97757045 |
| 4 | MP0001968_abnormal_touch/_nociception | 4.04696906 |
| 5 | MP0001529_abnormal_vocalization | 3.84358645 |
| 6 | MP0001984_abnormal_olfaction | 3.66195347 |
| 7 | MP0009379_abnormal_foot_pigmentation | 3.16505207 |
| 8 | MP0002736_abnormal_nociception_after | 2.78919682 |
| 9 | MP0008775_abnormal_heart_ventricle | 2.69425918 |
| 10 | MP0005257_abnormal_intraocular_pressure | 2.59459949 |
| 11 | MP0003011_delayed_dark_adaptation | 2.53031080 |
| 12 | MP0003890_abnormal_embryonic-extraembry | 2.37284736 |
| 13 | MP0005670_abnormal_white_adipose | 2.32263025 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 2.17716906 |
| 15 | MP0003959_abnormal_lean_body | 2.14029270 |
| 16 | MP0002163_abnormal_gland_morphology | 2.09144974 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.93303352 |
| 18 | MP0001764_abnormal_homeostasis | 1.92308965 |
| 19 | MP0009278_abnormal_bone_marrow | 1.87756282 |
| 20 | MP0002233_abnormal_nose_morphology | 1.66569128 |
| 21 | MP0003880_abnormal_central_pattern | 1.60271260 |
| 22 | MP0002089_abnormal_postnatal_growth/wei | 1.53649114 |
| 23 | MP0002822_catalepsy | 1.46072723 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.43799037 |
| 25 | MP0003183_abnormal_peptide_metabolism | 1.42339575 |
| 26 | MP0009697_abnormal_copulation | 1.37378056 |
| 27 | MP0003646_muscle_fatigue | 1.35245510 |
| 28 | MP0002160_abnormal_reproductive_system | 1.35210214 |
| 29 | MP0005167_abnormal_blood-brain_barrier | 1.34250516 |
| 30 | MP0000230_abnormal_systemic_arterial | 1.32250105 |
| 31 | MP0010030_abnormal_orbit_morphology | 1.31260125 |
| 32 | MP0005195_abnormal_posterior_eye | 1.28870786 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.27857182 |
| 34 | MP0002837_dystrophic_cardiac_calcinosis | 1.27711942 |
| 35 | MP0005084_abnormal_gallbladder_morpholo | 1.22872205 |
| 36 | MP0002735_abnormal_chemical_nociception | 1.22691929 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.19685342 |
| 38 | MP0003638_abnormal_response/metabolism_ | 1.19345004 |
| 39 | MP0000631_abnormal_neuroendocrine_gland | 1.17967173 |
| 40 | MP0003937_abnormal_limbs/digits/tail_de | 1.17713616 |
| 41 | MP0002932_abnormal_joint_morphology | 1.16046421 |
| 42 | MP0005646_abnormal_pituitary_gland | 1.13113968 |
| 43 | MP0003633_abnormal_nervous_system | 1.09527001 |
| 44 | MP0002090_abnormal_vision | 1.09396444 |
| 45 | MP0003119_abnormal_digestive_system | 1.06362729 |
| 46 | MP0008995_early_reproductive_senescence | 1.06273381 |
| 47 | MP0005253_abnormal_eye_physiology | 1.03884699 |
| 48 | MP0004484_altered_response_of | 1.01913507 |
| 49 | MP0002733_abnormal_thermal_nociception | 1.00755614 |
| 50 | MP0008004_abnormal_stomach_pH | 0.97357367 |
| 51 | MP0005408_hypopigmentation | 0.95351038 |
| 52 | MP0003195_calcinosis | 0.93076076 |
| 53 | MP0008872_abnormal_physiological_respon | 0.91669340 |
| 54 | MP0002752_abnormal_somatic_nervous | 0.90753640 |
| 55 | MP0005187_abnormal_penis_morphology | 0.90219034 |
| 56 | MP0001542_abnormal_bone_strength | 0.87323147 |
| 57 | MP0005503_abnormal_tendon_morphology | 0.85787426 |
| 58 | MP0000049_abnormal_middle_ear | 0.85782766 |
| 59 | MP0001905_abnormal_dopamine_level | 0.85775903 |
| 60 | MP0002697_abnormal_eye_size | 0.85368096 |
| 61 | MP0001501_abnormal_sleep_pattern | 0.84818015 |
| 62 | MP0004147_increased_porphyrin_level | 0.84259630 |
| 63 | MP0009764_decreased_sensitivity_to | 0.84184433 |
| 64 | MP0005360_urolithiasis | 0.82933367 |
| 65 | MP0001545_abnormal_hematopoietic_system | 0.81966427 |
| 66 | MP0005397_hematopoietic_system_phenotyp | 0.81966427 |
| 67 | MP0004142_abnormal_muscle_tone | 0.81603678 |
| 68 | MP0002132_abnormal_respiratory_system | 0.80408521 |
| 69 | MP0002109_abnormal_limb_morphology | 0.78906430 |
| 70 | MP0001340_abnormal_eyelid_morphology | 0.78614591 |
| 71 | MP0003631_nervous_system_phenotype | 0.76036955 |
| 72 | MP0001664_abnormal_digestion | 0.74903236 |
| 73 | MP0005410_abnormal_fertilization | 0.74668411 |
| 74 | MP0005334_abnormal_fat_pad | 0.71560760 |
| 75 | MP0001879_abnormal_lymphatic_vessel | 0.70410788 |
| 76 | MP0003878_abnormal_ear_physiology | 0.69881729 |
| 77 | MP0005377_hearing/vestibular/ear_phenot | 0.69881729 |
| 78 | MP0005376_homeostasis/metabolism_phenot | 0.69749761 |
| 79 | MP0005647_abnormal_sex_gland | 0.69341088 |
| 80 | MP0005448_abnormal_energy_balance | 0.68819802 |
| 81 | MP0000750_abnormal_muscle_regeneration | 0.68009816 |
| 82 | MP0001286_abnormal_eye_development | 0.67516988 |
| 83 | MP0002234_abnormal_pharynx_morphology | 0.67471247 |
| 84 | MP0000343_altered_response_to | 0.66940013 |
| 85 | MP0001661_extended_life_span | 0.65957910 |
| 86 | MP0009250_abnormal_appendicular_skeleto | 0.65900248 |
| 87 | MP0005379_endocrine/exocrine_gland_phen | 0.65688486 |
| 88 | MP0010771_integument_phenotype | 0.65259746 |
| 89 | MP0005391_vision/eye_phenotype | 0.65029147 |
| 90 | MP0003786_premature_aging | 0.64785731 |
| 91 | MP0002272_abnormal_nervous_system | 0.64677990 |
| 92 | MP0000427_abnormal_hair_cycle | 0.64567893 |
| 93 | MP0006035_abnormal_mitochondrial_morpho | 0.64012011 |
| 94 | MP0005464_abnormal_platelet_physiology | 0.63801212 |
| 95 | MP0003136_yellow_coat_color | 0.61275333 |
| 96 | MP0005508_abnormal_skeleton_morphology | 0.59998625 |
| 97 | MP0003121_genomic_imprinting | 0.59882631 |
| 98 | MP0003567_abnormal_fetal_cardiomyocyte | 0.59696927 |
| 99 | MP0003123_paternal_imprinting | 0.58006234 |
| 100 | MP0002557_abnormal_social/conspecific_i | 0.57293324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal pupillary function (HP:0007686) | 9.32870423 |
| 2 | Rectovaginal fistula (HP:0000143) | 5.41841585 |
| 3 | Rectal fistula (HP:0100590) | 5.41841585 |
| 4 | Cutaneous melanoma (HP:0012056) | 5.15835951 |
| 5 | Intestinal fistula (HP:0100819) | 4.53645518 |
| 6 | Vaginal fistula (HP:0004320) | 4.48375989 |
| 7 | Vitreoretinal degeneration (HP:0000655) | 4.29311214 |
| 8 | Palpebral edema (HP:0100540) | 3.72799242 |
| 9 | Adactyly (HP:0009776) | 3.63529740 |
| 10 | Hyperglycinemia (HP:0002154) | 3.50997043 |
| 11 | Medial flaring of the eyebrow (HP:0010747) | 3.34649842 |
| 12 | Congenital primary aphakia (HP:0007707) | 3.33747809 |
| 13 | Pendular nystagmus (HP:0012043) | 3.31077329 |
| 14 | Gait imbalance (HP:0002141) | 3.21036345 |
| 15 | Postaxial foot polydactyly (HP:0001830) | 3.13184717 |
| 16 | Attenuation of retinal blood vessels (HP:0007843) | 3.10671530 |
| 17 | Pancreatic fibrosis (HP:0100732) | 3.07871909 |
| 18 | Abnormal protein glycosylation (HP:0012346) | 3.05141547 |
| 19 | Abnormal glycosylation (HP:0012345) | 3.05141547 |
| 20 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.05141547 |
| 21 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.05141547 |
| 22 | Nephrogenic diabetes insipidus (HP:0009806) | 2.96181200 |
| 23 | Septate vagina (HP:0001153) | 2.95694293 |
| 24 | Microretrognathia (HP:0000308) | 2.93265698 |
| 25 | Colon cancer (HP:0003003) | 2.86406754 |
| 26 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.85093320 |
| 27 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.84815788 |
| 28 | Abolished electroretinogram (ERG) (HP:0000550) | 2.78389978 |
| 29 | Hydroureter (HP:0000072) | 2.77068020 |
| 30 | Poor coordination (HP:0002370) | 2.75650887 |
| 31 | Chorioretinal atrophy (HP:0000533) | 2.59903027 |
| 32 | Acute encephalopathy (HP:0006846) | 2.57758976 |
| 33 | Acute necrotizing encephalopathy (HP:0006965) | 2.54643302 |
| 34 | Congenital, generalized hypertrichosis (HP:0004540) | 2.49303676 |
| 35 | Optic disc pallor (HP:0000543) | 2.49211376 |
| 36 | Abnormality of the pupil (HP:0000615) | 2.48445066 |
| 37 | Scrotal hypoplasia (HP:0000046) | 2.47785137 |
| 38 | Chorioretinal coloboma (HP:0000567) | 2.44870756 |
| 39 | Genital tract atresia (HP:0001827) | 2.44545395 |
| 40 | Vaginal atresia (HP:0000148) | 2.44248533 |
| 41 | Hypoplastic left heart (HP:0004383) | 2.43920479 |
| 42 | Stenosis of the external auditory canal (HP:0000402) | 2.43913932 |
| 43 | Vertebral arch anomaly (HP:0008438) | 2.33314264 |
| 44 | Congenital hepatic fibrosis (HP:0002612) | 2.32756047 |
| 45 | Thyroid-stimulating hormone excess (HP:0002925) | 2.32310594 |
| 46 | Progressive macrocephaly (HP:0004481) | 2.30935356 |
| 47 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.29590078 |
| 48 | Abnormality of midbrain morphology (HP:0002418) | 2.23846347 |
| 49 | Molar tooth sign on MRI (HP:0002419) | 2.23846347 |
| 50 | Deformed tarsal bones (HP:0008119) | 2.22263479 |
| 51 | Entropion (HP:0000621) | 2.16941569 |
| 52 | 2-3 toe syndactyly (HP:0004691) | 2.16680742 |
| 53 | Calcaneovalgus deformity (HP:0001848) | 2.16026968 |
| 54 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.15138287 |
| 55 | Sparse eyelashes (HP:0000653) | 2.13647697 |
| 56 | Atresia of the external auditory canal (HP:0000413) | 2.11893996 |
| 57 | Partial duplication of thumb phalanx (HP:0009944) | 2.11870464 |
| 58 | Aplasia/Hypoplasia of the nipples (HP:0006709) | 2.11617001 |
| 59 | Conjunctival telangiectasia (HP:0000524) | 2.07301768 |
| 60 | Bifid tongue (HP:0010297) | 2.07109626 |
| 61 | Generalized aminoaciduria (HP:0002909) | 2.04572121 |
| 62 | Metaphyseal dysplasia (HP:0100255) | 2.03681285 |
| 63 | Increased corneal curvature (HP:0100692) | 2.02797576 |
| 64 | Keratoconus (HP:0000563) | 2.02797576 |
| 65 | Reticulocytopenia (HP:0001896) | 2.00200702 |
| 66 | Pancreatic cysts (HP:0001737) | 1.98227862 |
| 67 | Nausea (HP:0002018) | 1.97204225 |
| 68 | Mitochondrial inheritance (HP:0001427) | 1.96752427 |
| 69 | Thoracolumbar scoliosis (HP:0002944) | 1.95144663 |
| 70 | Left ventricular hypertrophy (HP:0001712) | 1.94338628 |
| 71 | Abnormality of DNA repair (HP:0003254) | 1.92715005 |
| 72 | Anencephaly (HP:0002323) | 1.92712195 |
| 73 | Partial duplication of the phalanx of hand (HP:0009999) | 1.91308996 |
| 74 | 3-Methylglutaconic aciduria (HP:0003535) | 1.91264977 |
| 75 | Beaking of vertebral bodies (HP:0004568) | 1.89415413 |
| 76 | Cupped ear (HP:0000378) | 1.87623264 |
| 77 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.85700439 |
| 78 | Postnatal microcephaly (HP:0005484) | 1.85683439 |
| 79 | Hypoplastic heart (HP:0001961) | 1.84774439 |
| 80 | Limb dystonia (HP:0002451) | 1.84390904 |
| 81 | Meningioma (HP:0002858) | 1.82810560 |
| 82 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.80335822 |
| 83 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.80335822 |
| 84 | Abnormality of glycolipid metabolism (HP:0010969) | 1.80335822 |
| 85 | Poor head control (HP:0002421) | 1.79362125 |
| 86 | Adrenal hypoplasia (HP:0000835) | 1.79354855 |
| 87 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.78985802 |
| 88 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.78608174 |
| 89 | True hermaphroditism (HP:0010459) | 1.76874087 |
| 90 | Specific learning disability (HP:0001328) | 1.76138214 |
| 91 | Primary adrenal insufficiency (HP:0008207) | 1.75160910 |
| 92 | Median cleft lip (HP:0000161) | 1.74935837 |
| 93 | Hyperkalemia (HP:0002153) | 1.74810456 |
| 94 | Hypoplastic iliac wings (HP:0002866) | 1.74755413 |
| 95 | Abnormality of the columella (HP:0009929) | 1.74383279 |
| 96 | Down-sloping shoulders (HP:0200021) | 1.73717628 |
| 97 | Short tibia (HP:0005736) | 1.73712848 |
| 98 | Optic nerve hypoplasia (HP:0000609) | 1.71292820 |
| 99 | Postaxial hand polydactyly (HP:0001162) | 1.70343386 |
| 100 | Renal cortical cysts (HP:0000803) | 1.69806056 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 4.43763033 |
| 2 | CASK | 4.36970434 |
| 3 | VRK2 | 4.15761131 |
| 4 | DYRK3 | 3.65080408 |
| 5 | PIK3CA | 3.51133905 |
| 6 | FRK | 3.48538668 |
| 7 | TAF1 | 3.08247133 |
| 8 | NUAK1 | 2.91144268 |
| 9 | CDC7 | 2.59776202 |
| 10 | BLK | 2.26933073 |
| 11 | NLK | 2.11451383 |
| 12 | TLK1 | 2.10211751 |
| 13 | TNIK | 1.86759820 |
| 14 | PIK3CG | 1.83096829 |
| 15 | MAP3K13 | 1.81567686 |
| 16 | STK38L | 1.80952980 |
| 17 | STK24 | 1.79146812 |
| 18 | DAPK1 | 1.78884333 |
| 19 | CSF1R | 1.61256506 |
| 20 | SCYL2 | 1.59928480 |
| 21 | DYRK2 | 1.57780542 |
| 22 | ADRBK1 | 1.57288812 |
| 23 | NME1 | 1.54767708 |
| 24 | MAP3K7 | 1.54193412 |
| 25 | MELK | 1.53648267 |
| 26 | VRK1 | 1.51213929 |
| 27 | FLT3 | 1.49708586 |
| 28 | NEK1 | 1.47116027 |
| 29 | CDK8 | 1.29409946 |
| 30 | PLK2 | 1.27271933 |
| 31 | PTK2B | 1.26933192 |
| 32 | DAPK2 | 1.22790834 |
| 33 | KIT | 1.21541480 |
| 34 | MAPKAPK5 | 1.20164323 |
| 35 | MKNK1 | 1.17833721 |
| 36 | GRK7 | 1.16295418 |
| 37 | TAOK3 | 1.14291287 |
| 38 | EPHA2 | 1.08513861 |
| 39 | EPHB2 | 1.05048214 |
| 40 | BMX | 1.04506088 |
| 41 | BMPR1B | 1.02933369 |
| 42 | TGFBR1 | 1.00079575 |
| 43 | GRK5 | 0.98206585 |
| 44 | STK3 | 0.97280355 |
| 45 | DYRK1A | 0.88070603 |
| 46 | DAPK3 | 0.87490917 |
| 47 | MST4 | 0.81934519 |
| 48 | OBSCN | 0.78951235 |
| 49 | CHUK | 0.76980155 |
| 50 | MATK | 0.76659786 |
| 51 | DYRK1B | 0.76219775 |
| 52 | MAP2K7 | 0.75910418 |
| 53 | PRKCG | 0.73197320 |
| 54 | CSNK1G2 | 0.73087380 |
| 55 | CSNK1G3 | 0.72380102 |
| 56 | CSNK1G1 | 0.67508458 |
| 57 | TYRO3 | 0.67087247 |
| 58 | PRKCE | 0.65835390 |
| 59 | MAP3K5 | 0.61732989 |
| 60 | ZAK | 0.61384453 |
| 61 | CSNK1A1L | 0.60790546 |
| 62 | TIE1 | 0.58104939 |
| 63 | FGFR1 | 0.57236973 |
| 64 | MAP3K6 | 0.56591530 |
| 65 | MAP2K4 | 0.55985373 |
| 66 | WNK4 | 0.55173616 |
| 67 | WNK3 | 0.53868866 |
| 68 | EPHA4 | 0.51191467 |
| 69 | FGFR2 | 0.50098135 |
| 70 | IKBKB | 0.48801275 |
| 71 | MAP3K9 | 0.48311283 |
| 72 | PLK3 | 0.47826754 |
| 73 | ACVR1B | 0.47530183 |
| 74 | MST1R | 0.46043763 |
| 75 | MAP2K3 | 0.44634156 |
| 76 | SIK1 | 0.44172077 |
| 77 | CAMK2A | 0.42756747 |
| 78 | STK11 | 0.41916809 |
| 79 | PASK | 0.40671990 |
| 80 | CDK9 | 0.37494830 |
| 81 | PLK4 | 0.37264130 |
| 82 | TRIM28 | 0.36365518 |
| 83 | CAMK2B | 0.35624477 |
| 84 | GRK1 | 0.34934188 |
| 85 | AURKB | 0.34926358 |
| 86 | ILK | 0.33636542 |
| 87 | CSNK2A2 | 0.33431813 |
| 88 | CCNB1 | 0.33182548 |
| 89 | MAP2K2 | 0.32957002 |
| 90 | INSRR | 0.30794114 |
| 91 | PLK1 | 0.30261494 |
| 92 | AKT2 | 0.29993836 |
| 93 | LRRK2 | 0.26796019 |
| 94 | PRKAA2 | 0.24868162 |
| 95 | LIMK1 | 0.23639355 |
| 96 | SYK | 0.23030862 |
| 97 | PHKG1 | 0.21766778 |
| 98 | PHKG2 | 0.21766778 |
| 99 | PRKCQ | 0.21674813 |
| 100 | PAK3 | 0.21503548 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 4.36854259 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.31564245 |
| 3 | Folate biosynthesis_Homo sapiens_hsa00790 | 3.27363108 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.96547540 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.85682170 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.77422189 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50474076 |
| 8 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.30451834 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.27763248 |
| 10 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.20962629 |
| 11 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.18011388 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.12057502 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.11046601 |
| 14 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.85171938 |
| 15 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.79164622 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.76776148 |
| 17 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.73157999 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.67540973 |
| 19 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.57129649 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.56060653 |
| 21 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.53170602 |
| 22 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.43758740 |
| 23 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.41828667 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.37986449 |
| 25 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.37627201 |
| 26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.35408977 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.34224575 |
| 28 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.32305758 |
| 29 | Retinol metabolism_Homo sapiens_hsa00830 | 1.28318098 |
| 30 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.27726958 |
| 31 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.19696299 |
| 32 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.19583969 |
| 33 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.18759914 |
| 34 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.18260141 |
| 35 | Morphine addiction_Homo sapiens_hsa05032 | 1.18135302 |
| 36 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.16336069 |
| 37 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.14270046 |
| 38 | Proteasome_Homo sapiens_hsa03050 | 1.13736437 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.07761439 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.03484370 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.03264222 |
| 42 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03038756 |
| 43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.01679096 |
| 44 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.96931973 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 0.91836825 |
| 46 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.90963686 |
| 47 | Homologous recombination_Homo sapiens_hsa03440 | 0.90751843 |
| 48 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.90537561 |
| 49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.87729644 |
| 50 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.85214850 |
| 51 | Nicotine addiction_Homo sapiens_hsa05033 | 0.83801662 |
| 52 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.83741053 |
| 53 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.82040351 |
| 54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.81551938 |
| 55 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.81267041 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.79099221 |
| 57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.77429740 |
| 58 | Taste transduction_Homo sapiens_hsa04742 | 0.76482928 |
| 59 | Circadian entrainment_Homo sapiens_hsa04713 | 0.74711229 |
| 60 | GABAergic synapse_Homo sapiens_hsa04727 | 0.74542744 |
| 61 | Salivary secretion_Homo sapiens_hsa04970 | 0.74397848 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.73353916 |
| 63 | Phototransduction_Homo sapiens_hsa04744 | 0.72132883 |
| 64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.70972610 |
| 65 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.69892424 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69697849 |
| 67 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.68114722 |
| 68 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.67841996 |
| 69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67161238 |
| 70 | RNA degradation_Homo sapiens_hsa03018 | 0.65498732 |
| 71 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.61089534 |
| 72 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60228776 |
| 73 | Mismatch repair_Homo sapiens_hsa03430 | 0.60140427 |
| 74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.60018816 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.56113132 |
| 76 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.54544665 |
| 77 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.53282946 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52794361 |
| 79 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.52252171 |
| 80 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.50642753 |
| 81 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.48681700 |
| 82 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48066635 |
| 83 | Alcoholism_Homo sapiens_hsa05034 | 0.47301911 |
| 84 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.44108819 |
| 85 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.39864472 |
| 86 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.36331101 |
| 87 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.35599077 |
| 88 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.35064346 |
| 89 | Platelet activation_Homo sapiens_hsa04611 | 0.34226323 |
| 90 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33902756 |
| 91 | Mineral absorption_Homo sapiens_hsa04978 | 0.32789302 |
| 92 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.31146090 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.28349232 |
| 94 | Tight junction_Homo sapiens_hsa04530 | 0.23887408 |
| 95 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.22883596 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.21640087 |
| 97 | Renin secretion_Homo sapiens_hsa04924 | 0.21415962 |
| 98 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.19996371 |
| 99 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.18017999 |
| 100 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.17878673 |

