PROSER3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.58459181
2behavioral response to nicotine (GO:0035095)5.34780842
3sperm motility (GO:0030317)4.47831148
4kinetochore organization (GO:0051383)4.32971718
5kinetochore assembly (GO:0051382)4.32261617
6protein polyglutamylation (GO:0018095)4.22605701
7regulation of cilium movement (GO:0003352)3.97776880
8CENP-A containing nucleosome assembly (GO:0034080)3.96666454
9daunorubicin metabolic process (GO:0044597)3.96078784
10polyketide metabolic process (GO:0030638)3.96078784
11doxorubicin metabolic process (GO:0044598)3.96078784
12multicellular organism reproduction (GO:0032504)3.91129736
13chromatin remodeling at centromere (GO:0031055)3.80136242
14epithelial cilium movement (GO:0003351)3.79398184
15meiotic chromosome segregation (GO:0045132)3.77625265
16acrosome reaction (GO:0007340)3.73391560
17DNA deamination (GO:0045006)3.73064377
18fucose catabolic process (GO:0019317)3.70591076
19L-fucose metabolic process (GO:0042354)3.70591076
20L-fucose catabolic process (GO:0042355)3.70591076
21detection of light stimulus involved in visual perception (GO:0050908)3.68170961
22detection of light stimulus involved in sensory perception (GO:0050962)3.68170961
23microtubule depolymerization (GO:0007019)3.64183400
24regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.55489913
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.55280211
26cilium or flagellum-dependent cell motility (GO:0001539)3.55239286
27negative regulation of telomere maintenance (GO:0032205)3.48219100
28DNA ligation (GO:0006266)3.44870129
29axoneme assembly (GO:0035082)3.41692510
30cellular ketone body metabolic process (GO:0046950)3.39933335
31indolalkylamine metabolic process (GO:0006586)3.36904624
32cilium movement (GO:0003341)3.36396700
33regulation of DNA endoreduplication (GO:0032875)3.33927655
34regulation of hippo signaling (GO:0035330)3.30447740
35axonemal dynein complex assembly (GO:0070286)3.25945506
36piRNA metabolic process (GO:0034587)3.24647818
37centriole assembly (GO:0098534)3.22188954
38negative regulation of DNA-dependent DNA replication (GO:2000104)3.21482824
39tRNA methylation (GO:0030488)3.20681607
40mitotic sister chromatid cohesion (GO:0007064)3.18946815
41maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.17553796
42regulation of action potential (GO:0098900)3.15058016
43DNA replication-independent nucleosome organization (GO:0034724)3.14884220
44DNA replication-independent nucleosome assembly (GO:0006336)3.14884220
45regulation of nuclear cell cycle DNA replication (GO:0033262)3.14282760
46rRNA catabolic process (GO:0016075)3.13374620
47positive regulation of action potential (GO:0045760)3.12574518
48spermatid development (GO:0007286)3.10408743
49attachment of spindle microtubules to kinetochore (GO:0008608)3.10205462
50kynurenine metabolic process (GO:0070189)3.09012796
51negative regulation of Rho protein signal transduction (GO:0035024)3.05673690
52mismatch repair (GO:0006298)3.05519684
53intra-S DNA damage checkpoint (GO:0031573)3.04935918
54nephron tubule morphogenesis (GO:0072078)3.03437885
55nephron epithelium morphogenesis (GO:0072088)3.03437885
56indole-containing compound catabolic process (GO:0042436)3.01807847
57indolalkylamine catabolic process (GO:0046218)3.01807847
58tryptophan catabolic process (GO:0006569)3.01807847
59cellular response to ATP (GO:0071318)3.00115145
60positive regulation of defense response to virus by host (GO:0002230)2.99871309
61histone H3-K4 trimethylation (GO:0080182)2.99292639
62ketone body metabolic process (GO:1902224)2.99244746
63DNA integration (GO:0015074)2.97911149
64spinal cord motor neuron differentiation (GO:0021522)2.97606820
65negative regulation of translation, ncRNA-mediated (GO:0040033)2.96533395
66regulation of translation, ncRNA-mediated (GO:0045974)2.96533395
67negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.96533395
68histone H3-K36 demethylation (GO:0070544)2.96292764
69replication fork processing (GO:0031297)2.92111944
70telomere maintenance via recombination (GO:0000722)2.91892902
71telomere maintenance via semi-conservative replication (GO:0032201)2.91697403
72DNA strand renaturation (GO:0000733)2.91136024
73protein K6-linked ubiquitination (GO:0085020)2.90748534
74fusion of sperm to egg plasma membrane (GO:0007342)2.90205588
75histone exchange (GO:0043486)2.89721561
76mitotic recombination (GO:0006312)2.88585158
77DNA methylation involved in gamete generation (GO:0043046)2.85880043
78cornea development in camera-type eye (GO:0061303)2.80722830
79regulation of microtubule-based movement (GO:0060632)2.80688972
80telomere maintenance via telomere lengthening (GO:0010833)2.80348872
81neural tube formation (GO:0001841)2.79752443
82reciprocal DNA recombination (GO:0035825)2.79051093
83reciprocal meiotic recombination (GO:0007131)2.79051093
84mannosylation (GO:0097502)2.78621510
85vitamin catabolic process (GO:0009111)2.77809965
86fat-soluble vitamin catabolic process (GO:0042363)2.77809965
87sperm-egg recognition (GO:0035036)2.75933463
88centriole replication (GO:0007099)2.72188492
89regulation of telomere maintenance (GO:0032204)2.72140608
90RNA destabilization (GO:0050779)2.71059699
91viral mRNA export from host cell nucleus (GO:0046784)2.70248726
92replicative senescence (GO:0090399)2.67641889
93nonmotile primary cilium assembly (GO:0035058)2.67387730
94cilium organization (GO:0044782)2.66594872
95water-soluble vitamin biosynthetic process (GO:0042364)2.64714544
96detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.64512094
97single strand break repair (GO:0000012)2.64118737
98regulation of double-strand break repair via homologous recombination (GO:0010569)2.62270998
99tryptophan metabolic process (GO:0006568)2.62206687
100NAD biosynthetic process (GO:0009435)2.61441772
101telomere maintenance (GO:0000723)2.61252651
102reproduction (GO:0000003)2.60825425
103DNA strand elongation (GO:0022616)2.60028760
104cilium assembly (GO:0042384)2.59460564
105protein K11-linked deubiquitination (GO:0035871)2.59320985
106negative regulation of mast cell activation (GO:0033004)2.59069139
107telomere maintenance via telomerase (GO:0007004)2.58604049
108regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.58558279
109regulation of mitotic spindle checkpoint (GO:1903504)2.58558279
110positive regulation of DNA-dependent DNA replication (GO:2000105)2.57199602
111male meiosis I (GO:0007141)2.56565326
112telomere organization (GO:0032200)2.56293674
113peptidyl-histidine modification (GO:0018202)2.55952090
114cilium morphogenesis (GO:0060271)2.55210104
115ATP-dependent chromatin remodeling (GO:0043044)2.54177608
116organic cation transport (GO:0015695)2.53753067
117DNA replication initiation (GO:0006270)2.53741722
118somite rostral/caudal axis specification (GO:0032525)2.51577577
119DNA strand elongation involved in DNA replication (GO:0006271)2.51121237
120recombinational repair (GO:0000725)2.51008026
121rRNA modification (GO:0000154)2.50939592
122cytoplasmic mRNA processing body assembly (GO:0033962)2.50081027
123mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.50033634
124mitochondrial respiratory chain complex I assembly (GO:0032981)2.50033634
125NADH dehydrogenase complex assembly (GO:0010257)2.50033634
126dendritic cell chemotaxis (GO:0002407)2.49441174
127primary amino compound metabolic process (GO:1901160)2.49305577
128cAMP catabolic process (GO:0006198)2.48137660
129mesenchymal cell differentiation involved in renal system development (GO:2001012)2.47241124
130mesenchymal cell differentiation involved in kidney development (GO:0072161)2.47241124
131positive regulation of CREB transcription factor activity (GO:0032793)2.46022191
132regulation of meiosis I (GO:0060631)2.45977076
133male meiosis (GO:0007140)2.45323936
134lateral sprouting from an epithelium (GO:0060601)2.44663210
135RNA-dependent DNA replication (GO:0006278)2.44196664
136mitotic sister chromatid segregation (GO:0000070)2.44036958
137protein complex biogenesis (GO:0070271)2.43941978
138positive regulation of oligodendrocyte differentiation (GO:0048714)2.43510316
139negative regulation of transcription regulatory region DNA binding (GO:2000678)2.42959771
140spindle assembly checkpoint (GO:0071173)2.42768452
141negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.42742361
142metaphase plate congression (GO:0051310)2.42013429
143definitive hemopoiesis (GO:0060216)2.41158850
144DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.41130526
145limb development (GO:0060173)2.41007316
146appendage development (GO:0048736)2.41007316
147histone H3-K4 methylation (GO:0051568)2.40979677
148DNA catabolic process, exonucleolytic (GO:0000738)2.40589296
149positive regulation of meiosis (GO:0045836)2.40357606
150DNA damage response, signal transduction resulting in transcription (GO:0042772)2.40290752
151DNA topological change (GO:0006265)2.40279447
152rRNA methylation (GO:0031167)2.40186209
153transmission of nerve impulse (GO:0019226)2.39707877
154DNA demethylation (GO:0080111)2.39703736
155DNA unwinding involved in DNA replication (GO:0006268)2.38681595
156cell proliferation in forebrain (GO:0021846)2.37884832
157V(D)J recombination (GO:0033151)2.37726959
158histone H2A acetylation (GO:0043968)2.37444140
159somatic hypermutation of immunoglobulin genes (GO:0016446)2.37269756
160somatic diversification of immune receptors via somatic mutation (GO:0002566)2.37269756
161peptidyl-lysine trimethylation (GO:0018023)2.36558657
162double-strand break repair via homologous recombination (GO:0000724)2.35888225
163spindle checkpoint (GO:0031577)2.34556271
164negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.34421903
165negative regulation of sister chromatid segregation (GO:0033046)2.34421903
166negative regulation of mitotic sister chromatid separation (GO:2000816)2.34421903
167negative regulation of mitotic sister chromatid segregation (GO:0033048)2.34421903
168motile cilium assembly (GO:0044458)2.34041283
169DNA recombination (GO:0006310)2.34026922
170establishment of chromosome localization (GO:0051303)2.33838811
171microtubule polymerization or depolymerization (GO:0031109)2.33808407
172DNA synthesis involved in DNA repair (GO:0000731)2.32055604
173negative regulation of chromosome segregation (GO:0051985)2.31588895
174snRNA processing (GO:0016180)2.31579088
175nucleotide-excision repair, DNA gap filling (GO:0006297)2.30016319
176preassembly of GPI anchor in ER membrane (GO:0016254)2.29946455
177mitotic spindle assembly checkpoint (GO:0007094)2.29878086
178deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.28975425
179cellular response to ionizing radiation (GO:0071479)2.28537869
180cell differentiation involved in metanephros development (GO:0072202)2.27893957
181sister chromatid segregation (GO:0000819)2.27268484
182regulation of mitotic metaphase/anaphase transition (GO:0030071)2.26582808
183negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.26544099

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.29333627
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.24505119
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.17586128
4ZNF274_21170338_ChIP-Seq_K562_Hela4.09181131
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.85784614
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.61995858
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.34767753
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.64242794
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.46786744
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.39592710
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.25491312
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.20093997
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17255191
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.13752932
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.10612939
16PCGF2_27294783_Chip-Seq_ESCs_Mouse2.08623351
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.08315069
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06951815
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.01744792
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.01669219
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.89678599
22ER_23166858_ChIP-Seq_MCF-7_Human1.86644941
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.86133780
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.85353739
25PCGF2_27294783_Chip-Seq_NPCs_Mouse1.79849705
26ERA_21632823_ChIP-Seq_H3396_Human1.77079773
27AR_21572438_ChIP-Seq_LNCaP_Human1.71381376
28YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.70852679
29DROSHA_22980978_ChIP-Seq_HELA_Human1.69505954
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.68629262
31NOTCH1_21737748_ChIP-Seq_TLL_Human1.68343003
32IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.68191836
33EST1_17652178_ChIP-ChIP_JURKAT_Human1.67476979
34SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.66736646
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.66409403
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.65033260
37DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.62351365
38SUZ12_27294783_Chip-Seq_NPCs_Mouse1.62178748
39IRF1_19129219_ChIP-ChIP_H3396_Human1.61472717
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.59695601
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59415855
42FOXP3_21729870_ChIP-Seq_TREG_Human1.59364119
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.58639670
44TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58639670
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.57880086
46POU5F1_16153702_ChIP-ChIP_HESCs_Human1.57171483
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.56625954
48GATA3_21878914_ChIP-Seq_MCF-7_Human1.55081079
49KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.54566533
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54525604
51EWS_26573619_Chip-Seq_HEK293_Human1.53409106
52CIITA_25753668_ChIP-Seq_RAJI_Human1.52961431
53MYC_18555785_ChIP-Seq_MESCs_Mouse1.52280168
54EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.51972489
55E2F1_21310950_ChIP-Seq_MCF-7_Human1.49919736
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49558749
57ETV2_25802403_ChIP-Seq_MESCs_Mouse1.48796153
58TP53_22573176_ChIP-Seq_HFKS_Human1.47517034
59VDR_23849224_ChIP-Seq_CD4+_Human1.45238914
60P300_19829295_ChIP-Seq_ESCs_Human1.44737196
61REST_21632747_ChIP-Seq_MESCs_Mouse1.43336713
62STAT3_23295773_ChIP-Seq_U87_Human1.41311014
63CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.40835259
64EZH2_27294783_Chip-Seq_NPCs_Mouse1.40730680
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.40418753
66NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.40360449
67HOXB4_20404135_ChIP-ChIP_EML_Mouse1.40145820
68HOXB7_26014856_ChIP-Seq_BT474_Human1.40036124
69FUS_26573619_Chip-Seq_HEK293_Human1.39886638
70SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.39550588
71SCL_19346495_ChIP-Seq_HPC-7_Human1.37544988
72NANOG_20526341_ChIP-Seq_ESCs_Human1.36860712
73TAF2_19829295_ChIP-Seq_ESCs_Human1.36847355
74JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.36773551
75MYC_19829295_ChIP-Seq_ESCs_Human1.35289248
76RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.34202627
77FOXA1_27270436_Chip-Seq_PROSTATE_Human1.32878557
78FOXA1_25329375_ChIP-Seq_VCAP_Human1.32878557
79CBP_20019798_ChIP-Seq_JUKART_Human1.32665063
80IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32665063
81EZH2_22144423_ChIP-Seq_EOC_Human1.32326218
82TAF15_26573619_Chip-Seq_HEK293_Human1.29994012
83ELK1_19687146_ChIP-ChIP_HELA_Human1.27541490
84NCOR_22424771_ChIP-Seq_293T_Human1.26998095
85MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26368929
86OCT4_20526341_ChIP-Seq_ESCs_Human1.25892113
87TCF4_23295773_ChIP-Seq_U87_Human1.25549903
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25471993
89CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.24986007
90VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.24750319
91TDRD3_21172665_ChIP-Seq_MCF-7_Human1.24292489
92MYC_19030024_ChIP-ChIP_MESCs_Mouse1.23941553
93THAP11_20581084_ChIP-Seq_MESCs_Mouse1.21933367
94ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20892904
95SUZ12_18555785_Chip-Seq_ESCs_Mouse1.20239715
96SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.19921431
97MYC_18358816_ChIP-ChIP_MESCs_Mouse1.19867132
98E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18596200
99HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.17767961
100TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17685746
101BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17481930
102EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17200156
103AR_25329375_ChIP-Seq_VCAP_Human1.17130149
104EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.16945675
105E2F1_20622854_ChIP-Seq_HELA_Human1.16239911
106WDR5_24793694_ChIP-Seq_LNCAP_Human1.16057069
107EZH2_27294783_Chip-Seq_ESCs_Mouse1.15769998
108STAT3_18555785_Chip-Seq_ESCs_Mouse1.15498108
109RAC3_21632823_ChIP-Seq_H3396_Human1.15110052
110EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.15009544
111YY1_21170310_ChIP-Seq_MESCs_Mouse1.14894476
112P53_21459846_ChIP-Seq_SAOS-2_Human1.14484591
113PHF8_20622854_ChIP-Seq_HELA_Human1.14142443
114FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.12360278
115ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11803210
116SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11401596
117GABP_17652178_ChIP-ChIP_JURKAT_Human1.10888996
118AUTS2_25519132_ChIP-Seq_293T-REX_Human1.09871080
119RUNX2_22187159_ChIP-Seq_PCA_Human1.08962485
120PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.08684098
121TTF2_22483619_ChIP-Seq_HELA_Human1.08287892
122GBX2_23144817_ChIP-Seq_PC3_Human1.08277743
123SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07938563
124IGF1R_20145208_ChIP-Seq_DFB_Human1.07905210
125ZFX_18555785_Chip-Seq_ESCs_Mouse1.07366275
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07070640
127P53_22387025_ChIP-Seq_ESCs_Mouse1.06696180
128SMAD4_21799915_ChIP-Seq_A2780_Human1.06627871
129LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06442781
130OCT4_18555785_Chip-Seq_ESCs_Mouse1.05936132
131E2F1_18555785_Chip-Seq_ESCs_Mouse1.05672500
132SMAD4_21741376_ChIP-Seq_EPCs_Human1.05586651
133RNF2_27304074_Chip-Seq_NSC_Mouse1.05173304
134NANOG_18555785_Chip-Seq_ESCs_Mouse1.03968878
135NMYC_18555785_Chip-Seq_ESCs_Mouse1.03790770
136NANOG_19829295_ChIP-Seq_ESCs_Human1.03585188
137SOX2_19829295_ChIP-Seq_ESCs_Human1.03585188
138CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03312923
139P300_18555785_Chip-Seq_ESCs_Mouse1.03028419
140ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02751461
141CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02618574
142AR_20517297_ChIP-Seq_VCAP_Human1.01284805
143NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01253700
144SUZ12_27294783_Chip-Seq_ESCs_Mouse1.00979648
145TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00830122
146PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00787987
147GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00504134
148RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00277987
149PRDM14_20953172_ChIP-Seq_ESCs_Human0.99471945
150MYC_18940864_ChIP-ChIP_HL60_Human0.99195653
151EED_16625203_ChIP-ChIP_MESCs_Mouse0.98744898
152CTCF_20526341_ChIP-Seq_ESCs_Human0.98671741
153VDR_22108803_ChIP-Seq_LS180_Human0.98313960
154SMAD3_21741376_ChIP-Seq_ESCs_Human0.98143420
155BCAT_22108803_ChIP-Seq_LS180_Human0.98026102
156SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.97931762
157GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97577045
158FLI1_21867929_ChIP-Seq_TH2_Mouse0.96418842
159ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96036734
160CMYC_18555785_Chip-Seq_ESCs_Mouse0.96030403
161IRF8_21731497_ChIP-ChIP_J774_Mouse0.95650488
162FOXH1_21741376_ChIP-Seq_ESCs_Human0.95414728
163SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.94969985
164EZH2_27304074_Chip-Seq_ESCs_Mouse0.94856614
165KLF4_18555785_Chip-Seq_ESCs_Mouse0.94530928
166TOP2B_26459242_ChIP-Seq_MCF-7_Human0.93880112
167P300_27268052_Chip-Seq_Bcells_Human0.93767165
168KLF5_20875108_ChIP-Seq_MESCs_Mouse0.92843924
169ESRRB_18555785_Chip-Seq_ESCs_Mouse0.92712053
170PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92653246
171JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92521752
172BCL6_27268052_Chip-Seq_Bcells_Human0.92412819
173CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92375744
174RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.92347152
175VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91262071
176SOX2_18555785_Chip-Seq_ESCs_Mouse0.89886679
177SOX9_26525672_Chip-Seq_HEART_Mouse0.88857345

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.03033928
2MP0000566_synostosis3.54426032
3MP0010094_abnormal_chromosome_stability3.25076799
4MP0005410_abnormal_fertilization3.24475192
5MP0008058_abnormal_DNA_repair3.09718422
6MP0008057_abnormal_DNA_replication2.93646761
7MP0002396_abnormal_hematopoietic_system2.64488655
8MP0003111_abnormal_nucleus_morphology2.63551361
9MP0001188_hyperpigmentation2.51123340
10MP0003646_muscle_fatigue2.41743541
11MP0008877_abnormal_DNA_methylation2.37306796
12MP0003941_abnormal_skin_development2.31238998
13MP0003787_abnormal_imprinting2.30660896
14MP0008007_abnormal_cellular_replicative2.25755922
15MP0002938_white_spotting2.21366739
16MP0002735_abnormal_chemical_nociception2.17854953
17MP0001968_abnormal_touch/_nociception2.13349858
18MP0003195_calcinosis2.12723732
19MP0003693_abnormal_embryo_hatching1.99831567
20MP0003077_abnormal_cell_cycle1.99571216
21MP0005174_abnormal_tail_pigmentation1.98179773
22MP0005075_abnormal_melanosome_morpholog1.93650784
23MP0005551_abnormal_eye_electrophysiolog1.93113733
24MP0005377_hearing/vestibular/ear_phenot1.84947956
25MP0003878_abnormal_ear_physiology1.84947956
26MP0008872_abnormal_physiological_respon1.84435799
27MP0002653_abnormal_ependyma_morphology1.84136025
28MP0003121_genomic_imprinting1.81189846
29MP0004142_abnormal_muscle_tone1.77674127
30MP0001293_anophthalmia1.76867106
31MP0000569_abnormal_digit_pigmentation1.76741010
32MP0004043_abnormal_pH_regulation1.74094401
33MP0000049_abnormal_middle_ear1.71680389
34MP0001986_abnormal_taste_sensitivity1.69884517
35MP0008961_abnormal_basal_metabolism1.64557477
36MP0002132_abnormal_respiratory_system1.61562619
37MP0009697_abnormal_copulation1.58029673
38MP0000015_abnormal_ear_pigmentation1.54946724
39MP0001348_abnormal_lacrimal_gland1.54869412
40MP0002102_abnormal_ear_morphology1.53939364
41MP0004381_abnormal_hair_follicle1.52556569
42MP0002249_abnormal_larynx_morphology1.52224992
43MP0002928_abnormal_bile_duct1.51598520
44MP0008932_abnormal_embryonic_tissue1.49747482
45MP0009046_muscle_twitch1.49737304
46MP0002277_abnormal_respiratory_mucosa1.47350254
47MP0004885_abnormal_endolymph1.47321562
48MP0005083_abnormal_biliary_tract1.46939429
49MP0000372_irregular_coat_pigmentation1.44843878
50MP0003718_maternal_effect1.43704786
51MP0005253_abnormal_eye_physiology1.41154958
52MP0003763_abnormal_thymus_physiology1.39823298
53MP0003136_yellow_coat_color1.39290298
54MP0002736_abnormal_nociception_after1.38956515
55MP0002557_abnormal_social/conspecific_i1.38841472
56MP0000678_abnormal_parathyroid_gland1.38718374
57MP0005171_absent_coat_pigmentation1.37888249
58MP0006072_abnormal_retinal_apoptosis1.37578704
59MP0003786_premature_aging1.37573351
60MP0006276_abnormal_autonomic_nervous1.32943712
61MP0009745_abnormal_behavioral_response1.32578213
62MP0001529_abnormal_vocalization1.32377083
63MP0002095_abnormal_skin_pigmentation1.31172473
64MP0005409_darkened_coat_color1.30238589
65MP0004957_abnormal_blastocyst_morpholog1.29857486
66MP0003890_abnormal_embryonic-extraembry1.29096022
67MP0002234_abnormal_pharynx_morphology1.29053114
68MP0004742_abnormal_vestibular_system1.28799083
69MP0002572_abnormal_emotion/affect_behav1.28610574
70MP0008995_early_reproductive_senescence1.27620242
71MP0002837_dystrophic_cardiac_calcinosis1.27344644
72MP0002163_abnormal_gland_morphology1.26346885
73MP0002733_abnormal_thermal_nociception1.25688904
74MP0005670_abnormal_white_adipose1.25687267
75MP0010030_abnormal_orbit_morphology1.23513949
76MP0003937_abnormal_limbs/digits/tail_de1.21868014
77MP0004808_abnormal_hematopoietic_stem1.21594980
78MP0002272_abnormal_nervous_system1.20445425
79MP0001873_stomach_inflammation1.20417115
80MP0002210_abnormal_sex_determination1.19492473
81MP0001835_abnormal_antigen_presentation1.17910267
82MP0001970_abnormal_pain_threshold1.17897872
83MP0001286_abnormal_eye_development1.16156690
84MP0008875_abnormal_xenobiotic_pharmacok1.16156442
85MP0000383_abnormal_hair_follicle1.15635901
86MP0001501_abnormal_sleep_pattern1.15022342
87MP0001485_abnormal_pinna_reflex1.14213018
88MP0000427_abnormal_hair_cycle1.13818823
89MP0003943_abnormal_hepatobiliary_system1.12175656
90MP0005671_abnormal_response_to1.11361714
91MP0002876_abnormal_thyroid_physiology1.11068133
92MP0004133_heterotaxia1.10915961
93MP0002638_abnormal_pupillary_reflex1.07496101
94MP0000703_abnormal_thymus_morphology1.06590890
95MP0002398_abnormal_bone_marrow1.06365078
96MP0003938_abnormal_ear_development1.05429066
97MP0001486_abnormal_startle_reflex1.00897308
98MP0005084_abnormal_gallbladder_morpholo1.00644729
99MP0001119_abnormal_female_reproductive1.00423202
100MP0004134_abnormal_chest_morphology1.00305989
101MP0000490_abnormal_crypts_of0.99375842
102MP0001502_abnormal_circadian_rhythm0.98901117
103MP0003119_abnormal_digestive_system0.98817681
104MP0005389_reproductive_system_phenotype0.98690885
105MP0009250_abnormal_appendicular_skeleto0.96761642
106MP0001800_abnormal_humoral_immune0.96603359
107MP0001919_abnormal_reproductive_system0.94701769
108MP0002138_abnormal_hepatobiliary_system0.94591443
109MP0003755_abnormal_palate_morphology0.94520559
110MP0001984_abnormal_olfaction0.94301731
111MP0003011_delayed_dark_adaptation0.93522318
112MP0002009_preneoplasia0.91932700
113MP0008789_abnormal_olfactory_epithelium0.91620454
114MP0003123_paternal_imprinting0.90998605
115MP0003385_abnormal_body_wall0.90288328
116MP0002148_abnormal_hypersensitivity_rea0.90055193
117MP0002160_abnormal_reproductive_system0.90007707
118MP0000026_abnormal_inner_ear0.89051936
119MP0005645_abnormal_hypothalamus_physiol0.88584401
120MP0001944_abnormal_pancreas_morphology0.88559747
121MP0005448_abnormal_energy_balance0.88370179
122MP0002752_abnormal_somatic_nervous0.88321993
123MP0003950_abnormal_plasma_membrane0.88213785
124MP0002116_abnormal_craniofacial_bone0.88108814
125MP0002067_abnormal_sensory_capabilities0.87766786
126MP0001346_abnormal_lacrimal_gland0.87585283
127MP0002161_abnormal_fertility/fecundity0.87561762
128MP0003283_abnormal_digestive_organ0.87072320
129MP0001145_abnormal_male_reproductive0.86945448
130MP0001790_abnormal_immune_system0.86850501
131MP0005387_immune_system_phenotype0.86850501
132MP0005195_abnormal_posterior_eye0.86807850
133MP0000778_abnormal_nervous_system0.86632291
134MP0005386_behavior/neurological_phenoty0.86021065
135MP0004924_abnormal_behavior0.86021065
136MP0001905_abnormal_dopamine_level0.85752543
137MP0003935_abnormal_craniofacial_develop0.85271550
138MP0005310_abnormal_salivary_gland0.85003761
139MP0001929_abnormal_gametogenesis0.84883550
140MP0002063_abnormal_learning/memory/cond0.84546226
141MP0002282_abnormal_trachea_morphology0.81789169
142MP0001324_abnormal_eye_pigmentation0.81637901
143MP0005646_abnormal_pituitary_gland0.80043827
144MP0002420_abnormal_adaptive_immunity0.79803714
145MP0002452_abnormal_antigen_presenting0.78982245
146MP0002109_abnormal_limb_morphology0.78972606
147MP0001819_abnormal_immune_cell0.78668368
148MP0000313_abnormal_cell_death0.78470497
149MP0002932_abnormal_joint_morphology0.77838162
150MP0000762_abnormal_tongue_morphology0.77338194
151MP0002075_abnormal_coat/hair_pigmentati0.77127504
152MP0003315_abnormal_perineum_morphology0.77048251
153MP0000631_abnormal_neuroendocrine_gland0.76594732
154MP0000653_abnormal_sex_gland0.76061620
155MP0000716_abnormal_immune_system0.75821634
156MP0004147_increased_porphyrin_level0.75533510
157MP0002722_abnormal_immune_system0.74743646
158MP0008004_abnormal_stomach_pH0.74534953
159MP0001186_pigmentation_phenotype0.74483698
160MP0002177_abnormal_outer_ear0.74421060
161MP0003698_abnormal_male_reproductive0.73773107
162MP0000432_abnormal_head_morphology0.73681371
163MP0002429_abnormal_blood_cell0.73241665
164MP0005379_endocrine/exocrine_gland_phen0.72124766
165MP0000350_abnormal_cell_proliferation0.71746531
166MP0002098_abnormal_vibrissa_morphology0.71661188

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.68957283
2Chromsome breakage (HP:0040012)5.63274050
3Duplicated collecting system (HP:0000081)3.95209909
4Type II lissencephaly (HP:0007260)3.92055789
5Congenital stationary night blindness (HP:0007642)3.84904496
6Attenuation of retinal blood vessels (HP:0007843)3.70944600
7Abnormality of the renal collecting system (HP:0004742)3.67675634
8Genetic anticipation (HP:0003743)3.60474280
9True hermaphroditism (HP:0010459)3.25782029
10Ectopic kidney (HP:0000086)3.18422785
11Abnormal rod and cone electroretinograms (HP:0008323)3.02541999
12Abnormality of the preputium (HP:0100587)3.00068898
13Tubular atrophy (HP:0000092)2.97279050
14Aplasia/Hypoplasia of the uvula (HP:0010293)2.94734606
15Abnormality of the renal cortex (HP:0011035)2.94671715
16Progressive cerebellar ataxia (HP:0002073)2.94409497
17Meckel diverticulum (HP:0002245)2.94400056
18Abnormality of chromosome stability (HP:0003220)2.90540130
19Prostate neoplasm (HP:0100787)2.88327563
20Lissencephaly (HP:0001339)2.88294094
21Birth length less than 3rd percentile (HP:0003561)2.87639980
22Abnormal drinking behavior (HP:0030082)2.81112436
23Polydipsia (HP:0001959)2.81112436
24Abnormality of the ileum (HP:0001549)2.80822950
25Bony spicule pigmentary retinopathy (HP:0007737)2.80570004
26Optic nerve coloboma (HP:0000588)2.69258633
27Cystic liver disease (HP:0006706)2.64412447
28Pancreatic fibrosis (HP:0100732)2.64035503
29Large for gestational age (HP:0001520)2.61157907
30Hyperventilation (HP:0002883)2.58470933
31Pancreatic cysts (HP:0001737)2.57752485
32Abnormality of DNA repair (HP:0003254)2.54442998
33Hypoplasia of the pons (HP:0012110)2.46601962
34Abnormality of the pons (HP:0007361)2.44369967
35Duplication of thumb phalanx (HP:0009942)2.43176152
36Clubbing of toes (HP:0100760)2.42770380
37Chronic hepatic failure (HP:0100626)2.42664264
38Inability to walk (HP:0002540)2.39786725
39Supernumerary spleens (HP:0009799)2.38160008
40Sclerocornea (HP:0000647)2.37679655
41Abnormal lung lobation (HP:0002101)2.33906619
42Polyuria (HP:0000103)2.33401100
43Severe muscular hypotonia (HP:0006829)2.30820495
44White forelock (HP:0002211)2.28032107
45Duodenal stenosis (HP:0100867)2.20082287
46Small intestinal stenosis (HP:0012848)2.20082287
47Abnormal respiratory motile cilium physiology (HP:0012261)2.19743979
48Gaze-evoked nystagmus (HP:0000640)2.18877963
49Absent/shortened dynein arms (HP:0200106)2.16338842
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.16338842
51Preaxial hand polydactyly (HP:0001177)2.16048069
52Patellar aplasia (HP:0006443)2.15629949
53Molar tooth sign on MRI (HP:0002419)2.12456204
54Abnormality of midbrain morphology (HP:0002418)2.12456204
55Patchy hypopigmentation of hair (HP:0011365)2.11699439
56Septo-optic dysplasia (HP:0100842)2.09147855
57Abnormality of the carotid arteries (HP:0005344)2.09099357
58Embryonal renal neoplasm (HP:0011794)2.08991966
59Nephroblastoma (Wilms tumor) (HP:0002667)2.08381618
60Abolished electroretinogram (ERG) (HP:0000550)2.08193251
61Concave nail (HP:0001598)2.07173392
62Anencephaly (HP:0002323)2.06653584
63Reticulocytopenia (HP:0001896)2.06405544
64Postaxial foot polydactyly (HP:0001830)2.04982495
65Keratoconus (HP:0000563)2.02673945
66Increased corneal curvature (HP:0100692)2.02673945
67Abnormal number of incisors (HP:0011064)2.02645103
68Impulsivity (HP:0100710)2.00944922
69Nephronophthisis (HP:0000090)2.00843262
70Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.00730298
71Chorioretinal atrophy (HP:0000533)1.99779003
72Sloping forehead (HP:0000340)1.99067798
73Congenital hepatic fibrosis (HP:0002612)1.99030990
74Abnormal respiratory epithelium morphology (HP:0012253)1.98979780
75Abnormal respiratory motile cilium morphology (HP:0005938)1.98979780
76Pachygyria (HP:0001302)1.95915895
77Abnormality of the columella (HP:0009929)1.95435661
78Aplasia cutis congenita (HP:0001057)1.95259337
79Aplasia/Hypoplasia of the patella (HP:0006498)1.95098832
80Abnormality of the incisor (HP:0000676)1.95093589
81Decreased central vision (HP:0007663)1.94912179
82Myelodysplasia (HP:0002863)1.94326784
83Congenital sensorineural hearing impairment (HP:0008527)1.94101028
84Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93755607
85Bilateral microphthalmos (HP:0007633)1.93273316
86Bone marrow hypocellularity (HP:0005528)1.93240365
87Bulbous nose (HP:0000414)1.93226267
88Triphalangeal thumb (HP:0001199)1.92284083
89Decreased circulating renin level (HP:0003351)1.91798732
90Acute lymphatic leukemia (HP:0006721)1.91012352
91Retinal dysplasia (HP:0007973)1.90910712
92Abnormal biliary tract physiology (HP:0012439)1.89704903
93Bile duct proliferation (HP:0001408)1.89704903
94Absent thumb (HP:0009777)1.88206306
95Abnormal ciliary motility (HP:0012262)1.88068398
96Abnormal urine output (HP:0012590)1.88003439
97Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.87340957
98Clumsiness (HP:0002312)1.86151093
99Abnormality of incisor morphology (HP:0011063)1.82391734
100Aplasia/Hypoplasia of the tibia (HP:0005772)1.78960694
101Aplasia involving forearm bones (HP:0009822)1.78297421
102Absent forearm bone (HP:0003953)1.78297421
103Rib fusion (HP:0000902)1.78196776
104Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.78051318
105Absent radius (HP:0003974)1.76316495
106Absent septum pellucidum (HP:0001331)1.76299901
107Midline defect of the nose (HP:0004122)1.76287794
108Optic nerve hypoplasia (HP:0000609)1.75956122
109Rhinitis (HP:0012384)1.75249888
110Type I transferrin isoform profile (HP:0003642)1.75050646
111Short middle phalanx of the 5th finger (HP:0004220)1.75028828
112Abnormality of the duodenum (HP:0002246)1.74938000
113Congenital, generalized hypertrichosis (HP:0004540)1.74571567
114Hypoalbuminemia (HP:0003073)1.74480780
115Abnormal albumin level (HP:0012116)1.74480780
116Severe visual impairment (HP:0001141)1.73234709
117Abnormal hair whorl (HP:0010721)1.72487738
118Abnormality of the nasal septum (HP:0000419)1.72296055
119Facial cleft (HP:0002006)1.71818276
120Aplasia/Hypoplasia of the sternum (HP:0006714)1.71471172
121Stomatitis (HP:0010280)1.70910993
122Cerebellar dysplasia (HP:0007033)1.69347190
123Volvulus (HP:0002580)1.69203492
124Hypoplastic ischia (HP:0003175)1.68797719
125Short thumb (HP:0009778)1.68739655
126Abnormality of the intervertebral disk (HP:0005108)1.68571715
127Abnormality of the prostate (HP:0008775)1.68347634
128Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.66928727
129Abnormality of alanine metabolism (HP:0010916)1.66928727
130Hyperalaninemia (HP:0003348)1.66928727
131Protruding tongue (HP:0010808)1.66307465
132Furrowed tongue (HP:0000221)1.65978004
133Abnormality of the renal medulla (HP:0100957)1.65681484
134Oligohydramnios (HP:0001562)1.65568966
135Morphological abnormality of the middle ear (HP:0008609)1.65320735
136Skull defect (HP:0001362)1.65223113
137Abnormality of the septum pellucidum (HP:0007375)1.65205669
138Methylmalonic acidemia (HP:0002912)1.64692226
139Highly arched eyebrow (HP:0002553)1.64557268
140Medial flaring of the eyebrow (HP:0010747)1.64230945
141Hemiparesis (HP:0001269)1.63891936
142Male pseudohermaphroditism (HP:0000037)1.63832328
143Agammaglobulinemia (HP:0004432)1.63582597
144Medulloblastoma (HP:0002885)1.63493641
145Aganglionic megacolon (HP:0002251)1.63129483
14611 pairs of ribs (HP:0000878)1.62729966
147Methylmalonic aciduria (HP:0012120)1.62699408
148Oligodactyly (hands) (HP:0001180)1.62579289
149Tubulointerstitial nephritis (HP:0001970)1.62476056
150Abnormality of the parietal bone (HP:0002696)1.62366059
151Selective tooth agenesis (HP:0001592)1.62243588
152Aplasia/Hypoplasia of the tongue (HP:0010295)1.61224860
153Acute myeloid leukemia (HP:0004808)1.60547342
154Long eyelashes (HP:0000527)1.60453811
155Pendular nystagmus (HP:0012043)1.59989024
156Intestinal atresia (HP:0011100)1.59903945
157Abnormality of male internal genitalia (HP:0000022)1.58727831
158Sex reversal (HP:0012245)1.56725805
159Abnormal sex determination (HP:0012244)1.56725805
160Occipital encephalocele (HP:0002085)1.56318488
161Meningocele (HP:0002435)1.54983560
162Abnormality of the fingertips (HP:0001211)1.54276288

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.76979963
2PNCK3.66407378
3PIK3CG2.74764277
4SIK32.72343452
5BUB12.69514481
6MAP4K22.65989813
7WNK42.56294808
8BRD42.52927410
9CAMK1G2.51075402
10ZAK2.44582846
11STK162.43198619
12TAOK32.29699892
13CDC72.24492703
14YES12.20362649
15SRPK12.17748626
16ACVR1B2.16321507
17VRK12.16229417
18IRAK42.11566646
19PLK42.07755443
20TXK2.06994437
21TRIM281.88094429
22CASK1.87728123
23MAP3K141.84827209
24BMPR1B1.83374293
25WNK31.82828123
26MKNK11.79678591
27CLK11.73551353
28NUAK11.67370957
29ATR1.66016814
30CDK71.57488150
31STK41.56677861
32CDK121.54889031
33EIF2AK21.52321030
34TTK1.49872084
35MKNK21.49723512
36CDK31.44073720
37CDK81.43203688
38PINK11.41672604
39INSRR1.38533510
40IRAK31.35786154
41CAMK1D1.32551663
42CHEK21.29225228
43TAF11.26903836
44KIT1.26667208
45BMPR21.25687236
46NEK21.23632521
47PRKCI1.19461428
48ERBB31.18958667
49PLK11.14474115
50WEE11.14447994
51PRPF4B1.08397191
52ADRBK11.08102486
53MUSK1.07826738
54TEC1.03310644
55GRK11.00171857
56PRKCG0.99212506
57CCNB10.96479819
58BCR0.96334803
59TLK10.94917201
60AKT30.94234443
61RPS6KA60.94193851
62SGK20.94177256
63DAPK20.93447059
64IRAK10.93224095
65CDK40.93014675
66BRSK20.92366301
67BTK0.91946135
68CHUK0.90502599
69MAP2K20.88443405
70OXSR10.88364385
71NEK90.86901941
72PTK2B0.86432909
73PRKCH0.86364350
74ATM0.86304744
75DYRK20.86284807
76MARK10.85504261
77NLK0.85386215
78PLK30.84931672
79CHEK10.84900708
80STK390.84484737
81CDK90.83839771
82MAPKAPK30.83635009
83ADRBK20.82145505
84BCKDK0.81871778
85FLT30.81746881
86STK380.81140072
87AURKB0.80881820
88STK30.78716018
89TIE10.78500450
90CSF1R0.77712910
91MAPK130.76858844
92WNK10.76533679
93IKBKB0.75999564
94DYRK30.75898250
95IRAK20.74948715
96CAMKK20.74812329
97VRK20.73157293
98CAMK10.72913660
99RPS6KA50.71247713
100MAPK150.71197465
101NEK60.64967217
102PAK30.64288291
103MAP4K10.63901199
104PRKCE0.62530910
105CSNK1G10.62516714
106PBK0.61398582
107NME10.61064749
108PKN10.60918618
109CSNK1A1L0.59393024
110MAP2K60.59206713
111PRKCZ0.58932580
112BLK0.58732492
113EPHA20.58107695
114TNIK0.57774411
115MARK30.56255807
116PASK0.54326062
117RPS6KA40.54064798
118CDK10.52406387
119STK38L0.52084276
120MAP2K10.52006371
121RPS6KL10.51226205
122RPS6KC10.51226205
123PRKAA10.50950277
124SGK4940.50101889
125SGK2230.50101889
126MST40.48767999
127CDK20.48644532
128NTRK30.47275091
129MAP3K60.45699530
130RPS6KA20.45450624
131PRKD20.45192121
132LYN0.44339184
133TGFBR10.44102070
134PLK20.44049320
135FGFR20.44032930
136MAP3K100.43847815
137CSNK2A10.43743975
138LCK0.43498315
139AKT10.42615779
140STK110.42597372
141SIK20.42471848
142CDK60.42312693
143MAPK70.41776431
144EIF2AK10.41653966
145JAK30.41560415
146TNK20.40899063
147CSNK1G30.40668145
148SGK30.40587858
149CAMK40.39946086
150MAP3K70.39451799
151CSNK1G20.37138547
152GRK60.36576050
153CAMKK10.36310975
154PRKCQ0.35806133
155PRKAA20.34891274
156MAPKAPK50.34694962
157MAPK80.33230422
158CDC42BPA0.31735863
159HIPK20.31499510
160MAP3K40.31327149
161MAPK110.30540720
162PHKG10.30467474
163PHKG20.30467474

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.59844826
2Homologous recombination_Homo sapiens_hsa034403.48537544
3DNA replication_Homo sapiens_hsa030303.27028535
4Mismatch repair_Homo sapiens_hsa034303.17270364
5Non-homologous end-joining_Homo sapiens_hsa034502.72554007
6Base excision repair_Homo sapiens_hsa034102.63554308
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.44638124
8RNA polymerase_Homo sapiens_hsa030202.43933496
9Selenocompound metabolism_Homo sapiens_hsa004502.40501187
10Spliceosome_Homo sapiens_hsa030402.39273694
11Nitrogen metabolism_Homo sapiens_hsa009102.31583686
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.30928682
13Maturity onset diabetes of the young_Homo sapiens_hsa049502.30029951
14Cell cycle_Homo sapiens_hsa041102.29284728
15Butanoate metabolism_Homo sapiens_hsa006502.20040314
16Basal transcription factors_Homo sapiens_hsa030222.07443102
17Nucleotide excision repair_Homo sapiens_hsa034202.05845558
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.01780697
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.98088923
20Taste transduction_Homo sapiens_hsa047421.97242939
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.90174814
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.87487956
23Pyrimidine metabolism_Homo sapiens_hsa002401.75903974
24Olfactory transduction_Homo sapiens_hsa047401.75325859
25Nicotine addiction_Homo sapiens_hsa050331.73008217
26RNA degradation_Homo sapiens_hsa030181.69739895
27Primary immunodeficiency_Homo sapiens_hsa053401.67984268
28mRNA surveillance pathway_Homo sapiens_hsa030151.67182146
29One carbon pool by folate_Homo sapiens_hsa006701.58830101
30RNA transport_Homo sapiens_hsa030131.55766675
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.53123431
32NF-kappa B signaling pathway_Homo sapiens_hsa040641.48446413
33Morphine addiction_Homo sapiens_hsa050321.45989207
34Herpes simplex infection_Homo sapiens_hsa051681.38315416
35Intestinal immune network for IgA production_Homo sapiens_hsa046721.35005326
36Basal cell carcinoma_Homo sapiens_hsa052171.33081317
37Sulfur relay system_Homo sapiens_hsa041221.32627194
38Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.31522924
39Ribosome_Homo sapiens_hsa030101.28602528
40ABC transporters_Homo sapiens_hsa020101.26854036
41Allograft rejection_Homo sapiens_hsa053301.24636135
42Measles_Homo sapiens_hsa051621.24269781
43Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.23446835
44Dorso-ventral axis formation_Homo sapiens_hsa043201.23181909
45Hematopoietic cell lineage_Homo sapiens_hsa046401.23141011
46p53 signaling pathway_Homo sapiens_hsa041151.21863751
47Transcriptional misregulation in cancer_Homo sapiens_hsa052021.21241918
48Purine metabolism_Homo sapiens_hsa002301.20178549
49Caffeine metabolism_Homo sapiens_hsa002321.13161144
50Insulin secretion_Homo sapiens_hsa049111.10793920
51Notch signaling pathway_Homo sapiens_hsa043301.09863692
52Tryptophan metabolism_Homo sapiens_hsa003801.07737524
53Fatty acid biosynthesis_Homo sapiens_hsa000611.03637164
54Autoimmune thyroid disease_Homo sapiens_hsa053201.01604137
55HTLV-I infection_Homo sapiens_hsa051660.99843747
56NOD-like receptor signaling pathway_Homo sapiens_hsa046210.98920216
57Steroid biosynthesis_Homo sapiens_hsa001000.96273057
58Oxidative phosphorylation_Homo sapiens_hsa001900.95364278
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.94998954
60Graft-versus-host disease_Homo sapiens_hsa053320.90651323
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.90230086
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.88336045
63Arachidonic acid metabolism_Homo sapiens_hsa005900.87201792
64Epstein-Barr virus infection_Homo sapiens_hsa051690.87136796
65GABAergic synapse_Homo sapiens_hsa047270.86517800
66Glycerolipid metabolism_Homo sapiens_hsa005610.85428527
67Huntingtons disease_Homo sapiens_hsa050160.85312688
68Toll-like receptor signaling pathway_Homo sapiens_hsa046200.83687987
69Circadian entrainment_Homo sapiens_hsa047130.83348981
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83118502
71Asthma_Homo sapiens_hsa053100.81878247
72Hedgehog signaling pathway_Homo sapiens_hsa043400.81763091
73Serotonergic synapse_Homo sapiens_hsa047260.81011935
74Steroid hormone biosynthesis_Homo sapiens_hsa001400.80074731
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79872054
76Calcium signaling pathway_Homo sapiens_hsa040200.79211509
77Systemic lupus erythematosus_Homo sapiens_hsa053220.78979837
78Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.78419540
79Ovarian steroidogenesis_Homo sapiens_hsa049130.78132382
80Sphingolipid metabolism_Homo sapiens_hsa006000.76423825
81Glutamatergic synapse_Homo sapiens_hsa047240.75150926
82Influenza A_Homo sapiens_hsa051640.75062564
83Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.73942013
84Leishmaniasis_Homo sapiens_hsa051400.73023101
85Regulation of autophagy_Homo sapiens_hsa041400.72831373
86Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.72581763
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72378031
88Wnt signaling pathway_Homo sapiens_hsa043100.71883972
89Jak-STAT signaling pathway_Homo sapiens_hsa046300.71810859
90Chemical carcinogenesis_Homo sapiens_hsa052040.71502569
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.71326924
92MicroRNAs in cancer_Homo sapiens_hsa052060.70365215
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.68694255
94Small cell lung cancer_Homo sapiens_hsa052220.68684795
95Histidine metabolism_Homo sapiens_hsa003400.68349064
96Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67894458
97Hepatitis B_Homo sapiens_hsa051610.67712404
98Salivary secretion_Homo sapiens_hsa049700.67548256
99Peroxisome_Homo sapiens_hsa041460.67341859
100B cell receptor signaling pathway_Homo sapiens_hsa046620.67253667
101Lysine degradation_Homo sapiens_hsa003100.66943448
102TNF signaling pathway_Homo sapiens_hsa046680.64485071
103Viral carcinogenesis_Homo sapiens_hsa052030.62329319
104Prostate cancer_Homo sapiens_hsa052150.61589163
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61437367
106Parkinsons disease_Homo sapiens_hsa050120.60151521
107Apoptosis_Homo sapiens_hsa042100.59078469
108Acute myeloid leukemia_Homo sapiens_hsa052210.58511197
109T cell receptor signaling pathway_Homo sapiens_hsa046600.57218059
110Pathways in cancer_Homo sapiens_hsa052000.56255841
111Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52615025
112Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52172412
113Vitamin digestion and absorption_Homo sapiens_hsa049770.50500166
114Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50342873
115Protein export_Homo sapiens_hsa030600.49188629
116Retinol metabolism_Homo sapiens_hsa008300.48544691
117Metabolic pathways_Homo sapiens_hsa011000.48476228
118Phototransduction_Homo sapiens_hsa047440.46630899
119Melanoma_Homo sapiens_hsa052180.46627229
120Cocaine addiction_Homo sapiens_hsa050300.45447531
121Osteoclast differentiation_Homo sapiens_hsa043800.44515882
122Legionellosis_Homo sapiens_hsa051340.44479671
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44429482
124Cardiac muscle contraction_Homo sapiens_hsa042600.44049851
125Viral myocarditis_Homo sapiens_hsa054160.43926468
126Cholinergic synapse_Homo sapiens_hsa047250.43383763
127FoxO signaling pathway_Homo sapiens_hsa040680.42611505
128Proteasome_Homo sapiens_hsa030500.42270066
129Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.41781572
130Chronic myeloid leukemia_Homo sapiens_hsa052200.41501075
131Primary bile acid biosynthesis_Homo sapiens_hsa001200.40943690
132Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.40326100
133Aldosterone synthesis and secretion_Homo sapiens_hsa049250.40248545
134Hippo signaling pathway_Homo sapiens_hsa043900.39945002
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.39388775
136Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39341822
137Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38463363
138Fat digestion and absorption_Homo sapiens_hsa049750.38462250
139PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37766471
140Ether lipid metabolism_Homo sapiens_hsa005650.37637791
141Colorectal cancer_Homo sapiens_hsa052100.37495659
142Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37146849
143Type I diabetes mellitus_Homo sapiens_hsa049400.36763701
144SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36755206
145cAMP signaling pathway_Homo sapiens_hsa040240.36017506
146Circadian rhythm_Homo sapiens_hsa047100.35162038
147alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34966232
148Pancreatic cancer_Homo sapiens_hsa052120.34565537
149Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.34537284
150Cyanoamino acid metabolism_Homo sapiens_hsa004600.34059703
151Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33460274
152Shigellosis_Homo sapiens_hsa051310.33317231
153Rheumatoid arthritis_Homo sapiens_hsa053230.32289214
154N-Glycan biosynthesis_Homo sapiens_hsa005100.31615319
155Axon guidance_Homo sapiens_hsa043600.31546556
156Toxoplasmosis_Homo sapiens_hsa051450.30781515
157TGF-beta signaling pathway_Homo sapiens_hsa043500.30477615
158Malaria_Homo sapiens_hsa051440.30211554
159Linoleic acid metabolism_Homo sapiens_hsa005910.29506890

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »