PRPF38B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)5.91310137
2translational termination (GO:0006415)5.78827696
3ribosomal small subunit biogenesis (GO:0042274)5.16750708
4ribosomal small subunit assembly (GO:0000028)5.14856734
5mitotic sister chromatid cohesion (GO:0007064)4.93367764
6histone H3-K4 trimethylation (GO:0080182)4.93101474
7maturation of SSU-rRNA (GO:0030490)4.86304365
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.64716424
9cotranslational protein targeting to membrane (GO:0006613)4.62624182
10translational elongation (GO:0006414)4.58659031
11protein targeting to ER (GO:0045047)4.55625675
12nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.44014394
13cellular protein complex disassembly (GO:0043624)4.36402949
14establishment of protein localization to endoplasmic reticulum (GO:0072599)4.35513248
15translational initiation (GO:0006413)4.17229421
16protein localization to endoplasmic reticulum (GO:0070972)4.16279242
17centriole replication (GO:0007099)4.12452525
18viral life cycle (GO:0019058)4.11630725
19antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.09939847
20histone H3-K4 methylation (GO:0051568)3.97186906
21ribosomal large subunit biogenesis (GO:0042273)3.90574149
22protein complex disassembly (GO:0043241)3.80396118
23nuclear pore complex assembly (GO:0051292)3.79687817
24establishment of protein localization to mitochondrial membrane (GO:0090151)3.76546062
25positive regulation of gamma-delta T cell activation (GO:0046645)3.75880811
26positive thymic T cell selection (GO:0045059)3.66514797
27kinetochore organization (GO:0051383)3.66320439
28macromolecular complex disassembly (GO:0032984)3.64552025
29peptidyl-lysine trimethylation (GO:0018023)3.61685354
30chromatin remodeling at centromere (GO:0031055)3.58660522
31mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.58390007
32nuclear-transcribed mRNA catabolic process (GO:0000956)3.54689937
33mRNA catabolic process (GO:0006402)3.45233913
34kinetochore assembly (GO:0051382)3.44820463
35negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.44257043
36negative regulation of translation, ncRNA-mediated (GO:0040033)3.44257043
37regulation of translation, ncRNA-mediated (GO:0045974)3.44257043
38ATP synthesis coupled proton transport (GO:0015986)3.44079491
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.44079491
40negative regulation of cell killing (GO:0031342)3.41665070
41negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.41665070
42histone H3-K36 demethylation (GO:0070544)3.34866966
43CENP-A containing nucleosome assembly (GO:0034080)3.33386633
44DNA topological change (GO:0006265)3.29641206
45RNA catabolic process (GO:0006401)3.28716175
46mature B cell differentiation (GO:0002335)3.25720718
47pore complex assembly (GO:0046931)3.19862234
48epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.19365052
49positive regulation of histone H3-K4 methylation (GO:0051571)3.18315880
50negative T cell selection (GO:0043383)3.18094962
51chaperone-mediated protein transport (GO:0072321)3.15777441
52ribonucleoprotein complex biogenesis (GO:0022613)3.13745089
53regulation of B cell receptor signaling pathway (GO:0050855)3.13366239
54negative thymic T cell selection (GO:0045060)3.13322251
55nuclear pore organization (GO:0006999)3.12330022
56exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.10479493
57positive T cell selection (GO:0043368)3.09609330
58nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.07628887
59regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.07047820
60regulation of mitotic spindle checkpoint (GO:1903504)3.07047820
61regulation of nuclear cell cycle DNA replication (GO:0033262)3.06554955
62DNA replication-independent nucleosome assembly (GO:0006336)3.06486382
63DNA replication-independent nucleosome organization (GO:0034724)3.06486382
64regulation of RNA export from nucleus (GO:0046831)3.04231543
65regulation of gamma-delta T cell differentiation (GO:0045586)3.03880478
66mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.02684507
67mitochondrial respiratory chain complex I assembly (GO:0032981)3.02684507
68NADH dehydrogenase complex assembly (GO:0010257)3.02684507
69spliceosomal complex assembly (GO:0000245)3.02395391
70histone H3-K9 methylation (GO:0051567)3.01090294
71regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.98342066
72histone H3-K9 modification (GO:0061647)2.98127493
73thymic T cell selection (GO:0045061)2.97899933
74translation (GO:0006412)2.97842113
75rRNA processing (GO:0006364)2.97176477
76mRNA stabilization (GO:0048255)2.96953703
77RNA stabilization (GO:0043489)2.96953703
78regulation of interleukin-12 biosynthetic process (GO:0045075)2.96299521
79DNA replication checkpoint (GO:0000076)2.95800124
80rRNA metabolic process (GO:0016072)2.95729928
81regulation of gamma-delta T cell activation (GO:0046643)2.94222314
82ncRNA catabolic process (GO:0034661)2.93303990
83regulation of DNA endoreduplication (GO:0032875)2.92653607
84histone exchange (GO:0043486)2.92621782
85mRNA splice site selection (GO:0006376)2.89263550
86neural tube formation (GO:0001841)2.88707286
87histone lysine methylation (GO:0034968)2.87482726
88termination of RNA polymerase II transcription (GO:0006369)2.86318680
89positive regulation by host of viral transcription (GO:0043923)2.86285442
90T cell selection (GO:0045058)2.85991117
91behavioral response to nicotine (GO:0035095)2.85644390
92centriole assembly (GO:0098534)2.84350817
93protein targeting to membrane (GO:0006612)2.83917990
94cellular component biogenesis (GO:0044085)2.80568439
95poly(A)+ mRNA export from nucleus (GO:0016973)2.79112071
96B cell receptor signaling pathway (GO:0050853)2.77539266
97lymph node development (GO:0048535)2.76248173
98antigen processing and presentation of endogenous antigen (GO:0019883)2.75970117
99DNA deamination (GO:0045006)2.70782195
100RNA splicing, via transesterification reactions (GO:0000375)2.70187334
101somite development (GO:0061053)2.70084880
102negative regulation of interleukin-12 production (GO:0032695)2.69951871
103interferon-gamma production (GO:0032609)2.69866643
104negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.69506811
105replication fork processing (GO:0031297)2.67949089
106peptidyl-lysine methylation (GO:0018022)2.66413318
107mRNA splicing, via spliceosome (GO:0000398)2.64956461
108RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.64956461
109mitochondrial respiratory chain complex assembly (GO:0033108)2.63655196
110rRNA catabolic process (GO:0016075)2.60664032
111protein complex biogenesis (GO:0070271)2.60350770
112regulation of interferon-beta biosynthetic process (GO:0045357)2.60211430
113B cell homeostasis (GO:0001782)2.59821567
114neutrophil activation (GO:0042119)2.58953110
115regulation of centriole replication (GO:0046599)2.56713551
116modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.56464979
117positive regulation by organism of defense response of other organism involved in symbiotic interact2.56464979
118modulation by symbiont of host immune response (GO:0052553)2.56464979
119positive regulation by symbiont of host defense response (GO:0052509)2.56464979
120modulation by symbiont of host defense response (GO:0052031)2.56464979
121modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.56464979
122monoubiquitinated protein deubiquitination (GO:0035520)2.56158641
123germinal center formation (GO:0002467)2.55843937
124mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.55242857
125V(D)J recombination (GO:0033151)2.54794087
126regulation of nucleobase-containing compound transport (GO:0032239)2.54475775
127otic vesicle formation (GO:0030916)2.54382957
128negative regulation of RNA splicing (GO:0033119)2.52797127
129regulation of mRNA splicing, via spliceosome (GO:0048024)2.52560752
130sister chromatid cohesion (GO:0007062)2.52509506
131positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.51914036
132double-strand break repair via homologous recombination (GO:0000724)2.50814712
133recombinational repair (GO:0000725)2.50388246
134definitive hemopoiesis (GO:0060216)2.50301882
135histone mRNA catabolic process (GO:0071044)2.49789883
136antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.49020970
137antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.49020970
138pre-miRNA processing (GO:0031054)2.48696477
139negative regulation of granulocyte differentiation (GO:0030853)2.48514745
1403-UTR-mediated mRNA stabilization (GO:0070935)2.48441853
141protein localization to kinetochore (GO:0034501)2.47510675
142negative regulation of B cell proliferation (GO:0030889)2.47313376
143regulation of B cell differentiation (GO:0045577)2.46576062
144positive regulation of B cell differentiation (GO:0045579)2.45836123
145* RNA splicing (GO:0008380)2.45649860
146forebrain neuron differentiation (GO:0021879)2.45582106
147leukocyte aggregation (GO:0070486)2.45402975
148protein neddylation (GO:0045116)2.43469608
149B cell proliferation (GO:0042100)2.41600247
150pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.41509178
151lymphocyte homeostasis (GO:0002260)2.41054185
152DNA-templated transcription, termination (GO:0006353)2.40481681
153regulation of telomere maintenance (GO:0032204)2.40059569
154attachment of spindle microtubules to kinetochore (GO:0008608)2.39989749
155megakaryocyte development (GO:0035855)2.39763799
156granulocyte activation (GO:0036230)2.38299937
157negative regulation of mRNA processing (GO:0050686)2.36753470
158negative regulation of histone methylation (GO:0031061)2.36688171
159dosage compensation (GO:0007549)2.36071250
160modulation by virus of host process (GO:0019054)2.34620823
161positive regulation of interferon-alpha production (GO:0032727)2.34270912
162regulation of T cell tolerance induction (GO:0002664)2.34054499
163histone H4-K12 acetylation (GO:0043983)2.33982740
164regulation of monocyte differentiation (GO:0045655)2.33571612
165embryonic hemopoiesis (GO:0035162)2.33152444
166NIK/NF-kappaB signaling (GO:0038061)2.32100227
167cytoplasmic mRNA processing body assembly (GO:0033962)2.31108862
168regulation of mRNA stability (GO:0043488)2.30645365
169positive regulation of granulocyte differentiation (GO:0030854)2.29838044
170modulation by symbiont of host cellular process (GO:0044068)2.29574690
171immunoglobulin mediated immune response (GO:0016064)2.29097825
172negative regulation of DNA-dependent DNA replication (GO:2000104)2.28001894
173histone methylation (GO:0016571)2.27997761
174myeloid dendritic cell activation (GO:0001773)2.27444935
175nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.26808085
176regulation of histone H3-K27 methylation (GO:0061085)2.26067359
177positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.26050813
178regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.26050813
179positive regulation of mRNA catabolic process (GO:0061014)2.25701539
180positive regulation of gene expression, epigenetic (GO:0045815)2.24591057
181mitotic chromosome condensation (GO:0007076)2.24550458
182alternative mRNA splicing, via spliceosome (GO:0000380)2.24277816
183embryonic camera-type eye morphogenesis (GO:0048596)2.22937340

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.55668049
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.00464131
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.50982277
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.31612669
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.74658109
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.48521362
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.44199482
8FOXM1_23109430_ChIP-Seq_U2OS_Human3.36651659
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.18706106
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.18474166
11* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.07317679
12TP63_19390658_ChIP-ChIP_HaCaT_Human3.04026937
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.94964927
14MYC_22102868_ChIP-Seq_BL_Human2.94599572
15* MYC_18555785_ChIP-Seq_MESCs_Mouse2.89812989
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.80972634
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.80183944
18SCL_19346495_ChIP-Seq_HPC-7_Human2.68882433
19IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.65575550
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.65275847
21IRF8_27001747_Chip-Seq_BMDM_Mouse2.64193076
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.63511511
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.53257099
24* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.52950254
25FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.51745037
26RUNX_20019798_ChIP-Seq_JUKART_Human2.51005356
27ELK1_19687146_ChIP-ChIP_HELA_Human2.50275905
28VDR_23849224_ChIP-Seq_CD4+_Human2.40366127
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.39881231
30* MYB_26560356_Chip-Seq_TH1_Human2.36202118
31EZH2_22144423_ChIP-Seq_EOC_Human2.28419507
32NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.26140762
33ETS1_20019798_ChIP-Seq_JURKAT_Human2.20889239
34CREB1_15753290_ChIP-ChIP_HEK293T_Human2.14851312
35* MYB_26560356_Chip-Seq_TH2_Human2.13027227
36* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.11440812
37BP1_19119308_ChIP-ChIP_Hs578T_Human2.10620248
38TTF2_22483619_ChIP-Seq_HELA_Human2.07675767
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04677631
40MYC_19079543_ChIP-ChIP_MESCs_Mouse2.03542941
41BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.03373035
42FUS_26573619_Chip-Seq_HEK293_Human2.02993677
43GATA1_22025678_ChIP-Seq_K562_Human2.00099585
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.99532635
45FOXP3_21729870_ChIP-Seq_TREG_Human1.99423859
46MAF_26560356_Chip-Seq_TH1_Human1.98034601
47* VDR_21846776_ChIP-Seq_THP-1_Human1.96727719
48MYC_18940864_ChIP-ChIP_HL60_Human1.96515185
49TCF7_22412390_ChIP-Seq_EML_Mouse1.95079617
50VDR_22108803_ChIP-Seq_LS180_Human1.92642700
51ZNF274_21170338_ChIP-Seq_K562_Hela1.91691769
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.86316204
53MYB_21317192_ChIP-Seq_ERMYB_Mouse1.84859708
54* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.82963537
55XRN2_22483619_ChIP-Seq_HELA_Human1.81900005
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79257723
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.77365412
58UTX_26944678_Chip-Seq_JUKART_Human1.76684459
59* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.73284369
60SPI1_23547873_ChIP-Seq_NB4_Human1.72718794
61* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.72113784
62* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.70756731
63* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66423452
64JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.66085819
65IRF1_19129219_ChIP-ChIP_H3396_Human1.64136058
66* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63921022
67STAT4_19710469_ChIP-ChIP_TH1__Mouse1.62688555
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.60946507
69RUNX1_22412390_ChIP-Seq_EML_Mouse1.60165405
70GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59544267
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.59121844
72VDR_24763502_ChIP-Seq_THP-1_Human1.57832489
73FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.56035754
74BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53396306
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.50018285
76PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49267289
77PU_27001747_Chip-Seq_BMDM_Mouse1.49245304
78PKCTHETA_26484144_Chip-Seq_BREAST_Human1.48498981
79* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.46044669
80MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45948432
81BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45095090
82SPI1_23127762_ChIP-Seq_K562_Human1.43613005
83* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.41858920
84CIITA_25753668_ChIP-Seq_RAJI_Human1.40479819
85Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.40356013
86STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.40008136
87FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37171254
88SMAD_19615063_ChIP-ChIP_OVARY_Human1.35375298
89KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.34886585
90KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.34698668
91KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.34698668
92KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.34698668
93* GATA3_27048872_Chip-Seq_THYMUS_Human1.33636316
94CBX2_27304074_Chip-Seq_ESCs_Mouse1.33041954
95ELF1_17652178_ChIP-ChIP_JURKAT_Human1.30563538
96* KDM2B_26808549_Chip-Seq_DND41_Human1.28259373
97RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.25634666
98STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24914452
99RNF2_27304074_Chip-Seq_NSC_Mouse1.24032540
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23002229
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23002229
102TP63_17297297_ChIP-ChIP_HaCaT_Human1.21252440
103FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.20738084
104E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.19981911
105SALL1_21062744_ChIP-ChIP_HESCs_Human1.17487410
106* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.15117993
107RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.14960977
108MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13372556
109CTBP1_25329375_ChIP-Seq_LNCAP_Human1.12977274
110GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.12462230
111SOX2_18555785_ChIP-Seq_MESCs_Mouse1.12211745
112* MAF_26560356_Chip-Seq_TH2_Human1.12132674
113CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.11828330
114POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.11005292
115TP53_16413492_ChIP-PET_HCT116_Human1.10973349
116POU3F2_20337985_ChIP-ChIP_501MEL_Human1.10686782
117SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08839218
118CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07933356
119SOX2_16153702_ChIP-ChIP_HESCs_Human1.07096388
120* GABP_19822575_ChIP-Seq_HepG2_Human1.06197653
121VDR_24787735_ChIP-Seq_THP-1_Human1.05794835
122GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05173762
123PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04616200
124KDM2B_26808549_Chip-Seq_SUP-B15_Human1.03734352
125POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.01897746
126RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01763803
127HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01068872
128KDM2B_26808549_Chip-Seq_JURKAT_Human1.01036841
129STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.99836564
130EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99565129
131ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99523797
132MYCN_18555785_ChIP-Seq_MESCs_Mouse0.98587093
133* NCOR1_26117541_ChIP-Seq_K562_Human0.97374469
134SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.97256234
135ZFP57_27257070_Chip-Seq_ESCs_Mouse0.96608113
136AR_21572438_ChIP-Seq_LNCaP_Human0.95392815
137* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95132025
138P300_19829295_ChIP-Seq_ESCs_Human0.94959090
139CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94888336
140ER_23166858_ChIP-Seq_MCF-7_Human0.93125256
141PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92633959
142GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92455107
143HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91548958
144FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.91526942
145KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90811735
146DCP1A_22483619_ChIP-Seq_HELA_Human0.90631381
147NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89905431
148TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.89361536
149MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.89003743
150TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88140198
151RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.87082883
152TAF15_26573619_Chip-Seq_HEK293_Human0.86407570
153DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86360916
154BRD4_25478319_ChIP-Seq_HGPS_Human0.86143592
155SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.85483144
156EWS_26573619_Chip-Seq_HEK293_Human0.85231740
157NANOG_16153702_ChIP-ChIP_HESCs_Human0.83702325
158FOXO3_23340844_ChIP-Seq_DLD1_Human0.83599577
159MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.82548139
160TCF4_18268006_ChIP-ChIP_LS174T_Human0.81544051
161ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.81537669
162* TP53_22573176_ChIP-Seq_HFKS_Human0.80232602
163* GATA3_26560356_Chip-Seq_TH2_Human0.80174999
164* ELK3_25401928_ChIP-Seq_HUVEC_Human0.79630055
165* GATA6_25053715_ChIP-Seq_YYC3_Human0.78158124
166* YY1_21170310_ChIP-Seq_MESCs_Mouse0.77104354
167TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77096946
168* NELFA_20434984_ChIP-Seq_ESCs_Mouse0.77054710
169PCGF2_27294783_Chip-Seq_NPCs_Mouse0.76876930
170CTBP2_25329375_ChIP-Seq_LNCAP_Human0.76793551
171* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.76751321
172GATA2_22383799_ChIP-Seq_G1ME_Mouse0.76112761
173ZFP281_27345836_Chip-Seq_ESCs_Mouse0.74684959
174* ETV1_20927104_ChIP-Seq_GIST48_Human0.74032831
175FLI1_27457419_Chip-Seq_LIVER_Mouse0.73899027
176EZH2_27304074_Chip-Seq_ESCs_Mouse0.73488133
177BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.73033543
178CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.72947754
179NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.72835344
180* KDM5A_27292631_Chip-Seq_BREAST_Human0.72259352
181NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.72094325
182THAP11_20581084_ChIP-Seq_MESCs_Mouse0.71243058
183UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.71109967

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.20163221
2MP0002396_abnormal_hematopoietic_system3.53147918
3MP0006292_abnormal_olfactory_placode3.42992524
4MP0001835_abnormal_antigen_presentation3.28658913
5MP0000569_abnormal_digit_pigmentation3.06105993
6MP0008057_abnormal_DNA_replication2.84998254
7MP0003136_yellow_coat_color2.52388990
8MP0005671_abnormal_response_to2.47607600
9MP0003787_abnormal_imprinting2.47210124
10MP0001800_abnormal_humoral_immune2.34384905
11MP0003693_abnormal_embryo_hatching2.32365598
12MP0003763_abnormal_thymus_physiology2.31124792
13MP0001790_abnormal_immune_system2.27218936
14MP0005387_immune_system_phenotype2.27218936
15MP0003890_abnormal_embryonic-extraembry2.26337413
16MP0000685_abnormal_immune_system2.23312086
17MP0005257_abnormal_intraocular_pressure2.13669724
18MP0004808_abnormal_hematopoietic_stem2.13005526
19MP0002452_abnormal_antigen_presenting2.08068846
20MP0000566_synostosis2.06862095
21MP0002398_abnormal_bone_marrow1.96596521
22MP0002420_abnormal_adaptive_immunity1.90864460
23MP0001819_abnormal_immune_cell1.90714491
24MP0001188_hyperpigmentation1.87401467
25MP0002723_abnormal_immune_serum1.87094937
26MP0002166_altered_tumor_susceptibility1.78058365
27MP0005000_abnormal_immune_tolerance1.77670633
28MP0003111_abnormal_nucleus_morphology1.77073094
29MP0004185_abnormal_adipocyte_glucose1.74430484
30MP0001485_abnormal_pinna_reflex1.74182904
31MP0010094_abnormal_chromosome_stability1.71522501
32MP0000716_abnormal_immune_system1.69456719
33MP0000703_abnormal_thymus_morphology1.67856178
34MP0001545_abnormal_hematopoietic_system1.67380349
35MP0005397_hematopoietic_system_phenotyp1.67380349
36MP0002009_preneoplasia1.64466008
37MP0006072_abnormal_retinal_apoptosis1.63684216
38MP0004742_abnormal_vestibular_system1.62762780
39MP0003077_abnormal_cell_cycle1.61158860
40MP0008995_early_reproductive_senescence1.60704105
41MP0005310_abnormal_salivary_gland1.60613601
42MP0003436_decreased_susceptibility_to1.58987077
43MP0004510_myositis1.58626988
44MP0002419_abnormal_innate_immunity1.54376905
45MP0002277_abnormal_respiratory_mucosa1.52542018
46MP0002722_abnormal_immune_system1.50819684
47MP0001851_eye_inflammation1.50061283
48MP0005025_abnormal_response_to1.50059640
49MP0001849_ear_inflammation1.49815950
50MP0002006_tumorigenesis1.49385535
51MP0002938_white_spotting1.48270988
52MP0002148_abnormal_hypersensitivity_rea1.43867283
53MP0000689_abnormal_spleen_morphology1.43302838
54MP0005174_abnormal_tail_pigmentation1.43023646
55MP0002405_respiratory_system_inflammati1.41810152
56MP0002429_abnormal_blood_cell1.39868463
57MP0001853_heart_inflammation1.39247308
58MP0000631_abnormal_neuroendocrine_gland1.38915498
59MP0001873_stomach_inflammation1.37084089
60MP0003303_peritoneal_inflammation1.36898106
61MP0005076_abnormal_cell_differentiation1.36788610
62MP0008007_abnormal_cellular_replicative1.36403783
63MP0009278_abnormal_bone_marrow1.36262979
64MP0002254_reproductive_system_inflammat1.35866195
65MP0005464_abnormal_platelet_physiology1.35759576
66MP0008877_abnormal_DNA_methylation1.35071706
67MP0004142_abnormal_muscle_tone1.32371140
68MP0001286_abnormal_eye_development1.31059860
69MP0000490_abnormal_crypts_of1.29628463
70MP0008961_abnormal_basal_metabolism1.28742967
71MP0001529_abnormal_vocalization1.28476909
72MP0009785_altered_susceptibility_to1.27737430
73MP0003567_abnormal_fetal_cardiomyocyte1.24871282
74MP0003300_gastrointestinal_ulcer1.23908606
75MP0010352_gastrointestinal_tract_polyps1.23866573
76MP0006082_CNS_inflammation1.23651031
77MP0003045_fibrosis1.23510470
78MP0003878_abnormal_ear_physiology1.22742877
79MP0005377_hearing/vestibular/ear_phenot1.22742877
80MP0004947_skin_inflammation1.20655497
81MP0002653_abnormal_ependyma_morphology1.20645241
82MP0001346_abnormal_lacrimal_gland1.20140829
83MP0000383_abnormal_hair_follicle1.19048758
84MP0010155_abnormal_intestine_physiology1.18046305
85MP0002822_catalepsy1.17941273
86MP0003828_pulmonary_edema1.17582971
87MP0008789_abnormal_olfactory_epithelium1.17349287
88MP0010307_abnormal_tumor_latency1.17101655
89MP0000372_irregular_coat_pigmentation1.16663999
90MP0002163_abnormal_gland_morphology1.16052830
91MP0003121_genomic_imprinting1.14243481
92MP0001986_abnormal_taste_sensitivity1.12334874
93MP0005084_abnormal_gallbladder_morpholo1.11682388
94MP0003786_premature_aging1.11252248
95MP0000049_abnormal_middle_ear1.10750862
96MP0002928_abnormal_bile_duct1.09307371
97MP0004885_abnormal_endolymph1.09049430
98MP0008058_abnormal_DNA_repair1.08272093
99MP0002210_abnormal_sex_determination1.07782954
100MP0002102_abnormal_ear_morphology1.07638849
101MP0005075_abnormal_melanosome_morpholog1.04666704
102MP0003123_paternal_imprinting1.04609737
103MP0003566_abnormal_cell_adhesion1.03755731
104MP0001919_abnormal_reproductive_system1.03165478
105MP0000350_abnormal_cell_proliferation1.02885738
106MP0002160_abnormal_reproductive_system1.01238436
107MP0001845_abnormal_inflammatory_respons1.00749720
108MP0000778_abnormal_nervous_system1.00581494
109MP0003937_abnormal_limbs/digits/tail_de1.00117162
110MP0005551_abnormal_eye_electrophysiolog0.99990498
111MP0003315_abnormal_perineum_morphology0.96566265
112MP0008932_abnormal_embryonic_tissue0.95544451
113MP0004264_abnormal_extraembryonic_tissu0.95396639
114MP0009333_abnormal_splenocyte_physiolog0.92703121
115MP0005389_reproductive_system_phenotype0.92168755
116MP0003938_abnormal_ear_development0.91460762
117MP0003984_embryonic_growth_retardation0.90531912
118MP0002933_joint_inflammation0.89522895
119MP0004133_heterotaxia0.88173293
120MP0002088_abnormal_embryonic_growth/wei0.87945566
121MP0002877_abnormal_melanocyte_morpholog0.85544178
122MP0000858_altered_metastatic_potential0.83818209
123MP0005646_abnormal_pituitary_gland0.83738812
124MP0002019_abnormal_tumor_incidence0.83685850
125MP0005394_taste/olfaction_phenotype0.83518682
126MP0005499_abnormal_olfactory_system0.83518682
127MP0003861_abnormal_nervous_system0.82546637
128MP0000313_abnormal_cell_death0.82323729
129MP0001145_abnormal_male_reproductive0.81504830
130MP0002086_abnormal_extraembryonic_tissu0.80340310
131MP0001672_abnormal_embryogenesis/_devel0.79292345
132MP0005380_embryogenesis_phenotype0.79292345
133MP0003448_altered_tumor_morphology0.79042662
134MP0002736_abnormal_nociception_after0.79030176
135MP0010030_abnormal_orbit_morphology0.78805756
136MP0001697_abnormal_embryo_size0.77411513
137MP0000733_abnormal_muscle_development0.77256795
138MP0003172_abnormal_lysosome_physiology0.77230298
139MP0005253_abnormal_eye_physiology0.77111001
140MP0001929_abnormal_gametogenesis0.76526181
141MP0002697_abnormal_eye_size0.75710685
142MP0000465_gastrointestinal_hemorrhage0.74985811
143MP0000653_abnormal_sex_gland0.74711180
144MP0002095_abnormal_skin_pigmentation0.73570045
145MP0005391_vision/eye_phenotype0.72520750
146MP0002752_abnormal_somatic_nervous0.72146943
147MP0004957_abnormal_blastocyst_morpholog0.72077799
148MP0001119_abnormal_female_reproductive0.71248102
149MP0009053_abnormal_anal_canal0.71223341
150MP0008872_abnormal_physiological_respon0.71062287
151MP0001293_anophthalmia0.71054318
152MP0003866_abnormal_defecation0.70387861
153MP0002998_abnormal_bone_remodeling0.70210320
154MP0002925_abnormal_cardiovascular_devel0.69512603
155MP0002751_abnormal_autonomic_nervous0.69384756
156MP0010678_abnormal_skin_adnexa0.69233174
157MP0002233_abnormal_nose_morphology0.69070494
158MP0001915_intracranial_hemorrhage0.68658025
159MP0003183_abnormal_peptide_metabolism0.68358383
160MP0002085_abnormal_embryonic_tissue0.68246696
161MP0003941_abnormal_skin_development0.67819830
162MP0000026_abnormal_inner_ear0.67757511
163MP0002084_abnormal_developmental_patter0.66879456
164MP0004381_abnormal_hair_follicle0.64977084
165MP0002638_abnormal_pupillary_reflex0.63235867
166MP0005195_abnormal_posterior_eye0.63032099
167MP0000427_abnormal_hair_cycle0.62906092
168MP0002067_abnormal_sensory_capabilities0.62520474
169MP0003943_abnormal_hepatobiliary_system0.62335197

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.82557512
2Reticulocytopenia (HP:0001896)4.10215562
3Abnormality of cells of the erythroid lineage (HP:0012130)3.62086044
4Lip pit (HP:0100267)3.40098862
5Volvulus (HP:0002580)3.33285566
6Recurrent fungal infections (HP:0002841)3.13034135
7Septo-optic dysplasia (HP:0100842)3.09340101
8Macrocytic anemia (HP:0001972)3.08885411
9Rib fusion (HP:0000902)3.07463723
10Abnormal number of erythroid precursors (HP:0012131)3.06448623
11Abnormality of midbrain morphology (HP:0002418)2.93234647
12Molar tooth sign on MRI (HP:0002419)2.93234647
13Ectopic kidney (HP:0000086)2.91767753
14Pallor (HP:0000980)2.86531286
15Chronic mucocutaneous candidiasis (HP:0002728)2.85871182
16Recurrent cutaneous fungal infections (HP:0011370)2.85871182
17Pancreatic cysts (HP:0001737)2.85675153
18Abnormality of the intervertebral disk (HP:0005108)2.81813417
19Eczematoid dermatitis (HP:0000976)2.80975008
20Pancreatic fibrosis (HP:0100732)2.77045687
21Recurrent viral infections (HP:0004429)2.77030789
22Thyroiditis (HP:0100646)2.76127353
23Autoimmune thrombocytopenia (HP:0001973)2.74875495
24Chromsome breakage (HP:0040012)2.74341139
25Long eyelashes (HP:0000527)2.63760753
26T lymphocytopenia (HP:0005403)2.60583440
27Abnormality of T cell number (HP:0011839)2.56940978
28Agammaglobulinemia (HP:0004432)2.56023499
29Acute necrotizing encephalopathy (HP:0006965)2.55442063
30Recurrent abscess formation (HP:0002722)2.54389582
31Abnormal number of incisors (HP:0011064)2.53481489
32Acute myeloid leukemia (HP:0004808)2.48469524
33Anophthalmia (HP:0000528)2.42496384
34Eosinophilia (HP:0001880)2.41016626
35Severe combined immunodeficiency (HP:0004430)2.37575192
36Cellulitis (HP:0100658)2.37480182
37True hermaphroditism (HP:0010459)2.35024014
38Increased hepatocellular lipid droplets (HP:0006565)2.34036307
39Recurrent bacterial skin infections (HP:0005406)2.33614062
40Aplasia/Hypoplasia of the uvula (HP:0010293)2.32482279
41Nephronophthisis (HP:0000090)2.32226040
42Prominent nose (HP:0000448)2.31886461
43Oligodactyly (hands) (HP:0001180)2.30851344
44Genetic anticipation (HP:0003743)2.28859071
45Limited elbow extension (HP:0001377)2.28312340
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.27304155
47Panhypogammaglobulinemia (HP:0003139)2.26626016
48Urethral obstruction (HP:0000796)2.24767581
49Lymphopenia (HP:0001888)2.23388064
50Prostate neoplasm (HP:0100787)2.21745694
51Vertebral arch anomaly (HP:0008438)2.18346966
52Chronic diarrhea (HP:0002028)2.17237933
53Mediastinal lymphadenopathy (HP:0100721)2.16624547
54Abnormality of cells of the lymphoid lineage (HP:0012140)2.16364815
55Colon cancer (HP:0003003)2.16159817
56Patellar aplasia (HP:0006443)2.15835786
57Abnormality of eosinophils (HP:0001879)2.14153671
58Abnormality of the nasal septum (HP:0000419)2.13276082
59Acute encephalopathy (HP:0006846)2.11965104
60Meckel diverticulum (HP:0002245)2.11949886
61Abnormality of the ileum (HP:0001549)2.11801324
62Granulocytopenia (HP:0001913)2.10087228
63Congenital, generalized hypertrichosis (HP:0004540)2.09557107
64Combined immunodeficiency (HP:0005387)2.08748443
65Abnormality of the labia minora (HP:0012880)2.08085892
66Absent septum pellucidum (HP:0001331)2.06997131
67Bilateral microphthalmos (HP:0007633)2.06981800
68Acute lymphatic leukemia (HP:0006721)2.06547137
69Lipid accumulation in hepatocytes (HP:0006561)2.06124746
70Pustule (HP:0200039)2.04766721
71Abnormal delayed hypersensitivity skin test (HP:0002963)2.03410970
72Mitochondrial inheritance (HP:0001427)2.02719589
73Aplasia/Hypoplasia of the patella (HP:0006498)2.02610585
74Abnormal mitochondria in muscle tissue (HP:0008316)2.02081113
75Triphalangeal thumb (HP:0001199)2.02079711
76Abnormality of the septum pellucidum (HP:0007375)2.01763217
77Abnormality of the renal medulla (HP:0100957)2.01118994
78Spinal cord lesions (HP:0100561)2.00876841
79Syringomyelia (HP:0003396)2.00876841
80Progressive macrocephaly (HP:0004481)1.99779792
81Abnormality of DNA repair (HP:0003254)1.98918044
82Leukocytosis (HP:0001974)1.98683313
83B lymphocytopenia (HP:0010976)1.98378158
84Abnormality of B cell number (HP:0010975)1.98378158
85Anal stenosis (HP:0002025)1.98125882
86Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97320916
87Meningitis (HP:0001287)1.97300775
88Recurrent pneumonia (HP:0006532)1.96238880
89Recurrent skin infections (HP:0001581)1.96213649
90Esophageal atresia (HP:0002032)1.95222012
91Absent thumb (HP:0009777)1.94641077
92Abnormality of T cells (HP:0002843)1.94602408
9311 pairs of ribs (HP:0000878)1.93897202
94Abnormality of the columella (HP:0009929)1.93337253
95Periodontitis (HP:0000704)1.93023003
96Abnormality of the pons (HP:0007361)1.91771462
97Medial flaring of the eyebrow (HP:0010747)1.91704404
98Stenosis of the external auditory canal (HP:0000402)1.90524584
99Increased CSF lactate (HP:0002490)1.89955052
100IgM deficiency (HP:0002850)1.89829288
101Narrow palate (HP:0000189)1.89548488
102Osteomyelitis (HP:0002754)1.88432658
103Oligodontia (HP:0000677)1.88242879
104Absent frontal sinuses (HP:0002688)1.86594000
105Myositis (HP:0100614)1.86299920
106Hypoplasia of the pons (HP:0012110)1.85967844
107Myelodysplasia (HP:0002863)1.85314513
108Aplasia/Hypoplasia of the sternum (HP:0006714)1.85314064
109Inflammation of the large intestine (HP:0002037)1.83906901
110Abnormality of the preputium (HP:0100587)1.83859806
111Anencephaly (HP:0002323)1.81735616
112Supernumerary ribs (HP:0005815)1.81293940
113Impulsivity (HP:0100710)1.80826636
114Missing ribs (HP:0000921)1.80607646
115Median cleft lip (HP:0000161)1.80425365
116Vasculitis (HP:0002633)1.79833244
117Progressive cerebellar ataxia (HP:0002073)1.79777106
1183-Methylglutaconic aciduria (HP:0003535)1.79690177
119Deep philtrum (HP:0002002)1.78646609
120Recurrent bronchitis (HP:0002837)1.78458865
121Duplicated collecting system (HP:0000081)1.78010674
122Chronic otitis media (HP:0000389)1.77940610
123Chronic obstructive pulmonary disease (HP:0006510)1.77729790
124Obstructive lung disease (HP:0006536)1.77729790
125Sclerocornea (HP:0000647)1.76853475
126IgA deficiency (HP:0002720)1.76050432
127Abnormality of renal resorption (HP:0011038)1.75470290
128Oligodactyly (HP:0012165)1.75209204
129Lymphoma (HP:0002665)1.74371824
130Abnormality of the renal cortex (HP:0011035)1.74308848
131Clubbing of toes (HP:0100760)1.73731567
132Birth length less than 3rd percentile (HP:0003561)1.73090411
133Respiratory difficulties (HP:0002880)1.73061998
134Gastrointestinal atresia (HP:0002589)1.72761806
135Sloping forehead (HP:0000340)1.72542136
136Blepharitis (HP:0000498)1.72064168
137Abnormality of the parietal bone (HP:0002696)1.71981901
138IgG deficiency (HP:0004315)1.71103887
139Abnormality of the renal collecting system (HP:0004742)1.70720780
140Colitis (HP:0002583)1.70521441
141Hypoplasia of the radius (HP:0002984)1.70443438
142Facial hemangioma (HP:0000329)1.70219769
143Prolonged bleeding time (HP:0003010)1.69592786
144Ectropion (HP:0000656)1.69452423
145Optic nerve coloboma (HP:0000588)1.69093819
146Cheilitis (HP:0100825)1.68746360
147Abnormality of chromosome stability (HP:0003220)1.68156684
148Abnormality of the prostate (HP:0008775)1.67993666
149Preaxial hand polydactyly (HP:0001177)1.67899421
150Maternal diabetes (HP:0009800)1.67878762
151Recurrent lower respiratory tract infections (HP:0002783)1.67108880
152Gastrointestinal inflammation (HP:0004386)1.66771590
153Congenital primary aphakia (HP:0007707)1.66754336
154Aplasia cutis congenita (HP:0001057)1.66299375
155Wide nose (HP:0000445)1.65945799
156Pendular nystagmus (HP:0012043)1.65221105
157Small epiphyses (HP:0010585)1.64868262
158Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.64793203
159Thrombocytosis (HP:0001894)1.64628295
160Intestinal atresia (HP:0011100)1.63915356
161Smooth philtrum (HP:0000319)1.63690192
162Holoprosencephaly (HP:0001360)1.63211755
163Hemivertebrae (HP:0002937)1.62973699
164Increased nuchal translucency (HP:0010880)1.62814927
165Depressed nasal ridge (HP:0000457)1.62319055
166Abnormal lung lobation (HP:0002101)1.62308538
167Aplastic anemia (HP:0001915)1.61970354
168Supernumerary bones of the axial skeleton (HP:0009144)1.61534223
169Abnormality of the incisor (HP:0000676)1.61403429
170Cerebral edema (HP:0002181)1.61254073
171Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.61053342
172Hematochezia (HP:0002573)1.61021065
173Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.60839871
174Cystic liver disease (HP:0006706)1.60760107
175Hypoplasia of the thymus (HP:0000778)1.57251313
176Large eyes (HP:0001090)1.56730648
177Gingivitis (HP:0000230)1.56588738
178Sparse lateral eyebrow (HP:0005338)1.55834930
179Agnosia (HP:0010524)1.55280236
180Hypochromic anemia (HP:0001931)1.54989529
181Microtia (HP:0008551)1.54725274
182Dislocated radial head (HP:0003083)1.54390647
183Macroorchidism (HP:0000053)1.52480852
184Depressed nasal tip (HP:0000437)1.51463816

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.39414538
2PNCK3.73325566
3MAP4K12.83786335
4WEE12.57098698
5TXK2.51197559
6BRD42.47673769
7WNK42.32477100
8TNIK2.30935652
9CDC72.25531235
10STK162.23991703
11TSSK62.21605629
12MAP3K142.20648259
13LATS12.09594570
14BRSK22.07817881
15CAMK1D2.00007015
16NUAK11.96303141
17TAF11.86269051
18CDK81.80809549
19SIK31.77954139
20SIK21.75942305
21PASK1.74687708
22JAK31.72917667
23TGFBR21.64186090
24WNK31.61082718
25ITK1.60081439
26STK101.57713695
27CLK11.54027577
28TEC1.52864716
29CAMK1G1.52491183
30JAK11.50039320
31TYK21.48567703
32BUB11.46124606
33MAPK151.43372998
34MARK31.42792964
35IRAK41.39509898
36BMPR1B1.39086902
37CHUK1.38841868
38RPS6KA41.37960300
39STK31.36353839
40NEK21.36064731
41TAOK31.34283852
42DMPK1.33715615
43STK391.29205497
44KIT1.29097970
45PDK21.28754753
46NTRK21.25883893
47MKNK21.23600200
48DYRK31.19594947
49BTK1.18836961
50CDK61.18776866
51HCK1.17933336
52IKBKB1.17390635
53CDK71.15202369
54ATR1.14379613
55ZAP701.13712367
56CAMKK21.08076820
57FGFR31.06896169
58RIPK41.06507837
59BLK1.05178260
60STK41.03417984
61PLK31.00995121
62PIM11.00721866
63SYK0.97537213
64MAP3K100.96871022
65VRK20.95620168
66IRAK30.95209180
67IKBKE0.94934845
68VRK10.94492094
69CSF1R0.94475725
70LCK0.93889392
71CSK0.92653930
72CDK40.92587014
73EPHA30.91901795
74MKNK10.90239605
75LYN0.89939364
76CDK90.88968911
77SRPK10.88112189
78PLK10.87411206
79FRK0.83617421
80PIK3CA0.83035619
81ATM0.82903301
82NLK0.82843411
83MTOR0.82453255
84CHEK10.81484823
85SIK10.80474204
86MARK20.80192961
87CASK0.79734742
88INSRR0.78489697
89CDK30.78334779
90DYRK20.78169415
91CHEK20.77207645
92TAOK10.76338167
93TRIM280.75525702
94PLK40.75350361
95PRKAA20.74634842
96PDGFRB0.74306234
97NEK90.72443768
98NME10.71477204
99EEF2K0.70928710
100CSNK1E0.70909606
101CDK190.70122186
102TLK10.69496388
103TBK10.69100093
104UHMK10.68979152
105OXSR10.68601984
106PAK30.67869559
107TRPM70.67585129
108TGFBR10.66721982
109MAPK130.64960103
110CSNK2A20.64959754
111ZAK0.64853813
112CDK20.64782142
113IRAK10.64488897
114FGFR40.62792172
115ACVR1B0.62774443
116MAP2K20.62733464
117ALK0.62696878
118YES10.62494758
119EIF2AK20.61780931
120MAPKAPK20.60320323
121MAP3K130.59929329
122MAPK140.59593468
123ERN10.59332402
124ADRBK20.58742026
125STK110.56304470
126PRKD20.54879111
127AURKB0.54693295
128TYRO30.53905966
129GRK10.53313465
130PRKCG0.53302637
131TTK0.52390986
132MELK0.50702807
133FGFR10.50312125
134HIPK20.49050669
135CSNK2A10.48971660
136WNK10.48319185
137MAPK110.47670435
138ABL10.47387452
139MAP3K60.46059389
140PRKCQ0.45919508
141CAMK40.45868340
142TAOK20.45089999
143BRSK10.42956419
144AKT10.42184756
145RPS6KB20.42139334
146RPS6KA50.41532409
147JAK20.41309993
148CDK10.40598727
149BMPR20.40282754
150MAP4K20.39389011
151GSK3B0.38482381
152PRKDC0.37909665
153GRK60.36387740
154DYRK1A0.35892274

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.50943804
2Primary immunodeficiency_Homo sapiens_hsa053402.77760874
3RNA polymerase_Homo sapiens_hsa030202.51023170
4Oxidative phosphorylation_Homo sapiens_hsa001902.49032523
5Protein export_Homo sapiens_hsa030602.43956994
6Parkinsons disease_Homo sapiens_hsa050122.26214363
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.23792002
8B cell receptor signaling pathway_Homo sapiens_hsa046622.03389852
9Osteoclast differentiation_Homo sapiens_hsa043801.89283539
10Herpes simplex infection_Homo sapiens_hsa051681.85694135
11Measles_Homo sapiens_hsa051621.85330682
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.83640471
13Huntingtons disease_Homo sapiens_hsa050161.81311147
14Nucleotide excision repair_Homo sapiens_hsa034201.79476058
15Leishmaniasis_Homo sapiens_hsa051401.75281723
16Hematopoietic cell lineage_Homo sapiens_hsa046401.68720050
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.62350408
18T cell receptor signaling pathway_Homo sapiens_hsa046601.56000998
19Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.55020450
20Antigen processing and presentation_Homo sapiens_hsa046121.53766342
21Transcriptional misregulation in cancer_Homo sapiens_hsa052021.49590099
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49470580
23Chronic myeloid leukemia_Homo sapiens_hsa052201.45647674
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.42932705
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.39530329
26Basal transcription factors_Homo sapiens_hsa030221.38035026
27Lysine degradation_Homo sapiens_hsa003101.36764812
28Influenza A_Homo sapiens_hsa051641.36279211
29Proteasome_Homo sapiens_hsa030501.35545654
30mRNA surveillance pathway_Homo sapiens_hsa030151.35033428
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.34355011
32Alzheimers disease_Homo sapiens_hsa050101.33757765
33Hepatitis B_Homo sapiens_hsa051611.30231408
34Non-homologous end-joining_Homo sapiens_hsa034501.29261793
35Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.28786801
36Phototransduction_Homo sapiens_hsa047441.28350334
37Pancreatic cancer_Homo sapiens_hsa052121.27593288
38Small cell lung cancer_Homo sapiens_hsa052221.26726701
39Acute myeloid leukemia_Homo sapiens_hsa052211.26452489
40Adherens junction_Homo sapiens_hsa045201.24836551
41RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.22939947
42Toxoplasmosis_Homo sapiens_hsa051451.21500163
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.19377596
44Cardiac muscle contraction_Homo sapiens_hsa042601.19272736
45MicroRNAs in cancer_Homo sapiens_hsa052061.18678019
46TNF signaling pathway_Homo sapiens_hsa046681.17866543
47HTLV-I infection_Homo sapiens_hsa051661.16200775
48Notch signaling pathway_Homo sapiens_hsa043301.14716866
49Homologous recombination_Homo sapiens_hsa034401.14513854
50Allograft rejection_Homo sapiens_hsa053301.14407059
51* Spliceosome_Homo sapiens_hsa030401.14317103
52Nicotine addiction_Homo sapiens_hsa050331.11828985
53Chemokine signaling pathway_Homo sapiens_hsa040621.10846355
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.10416419
55Pyrimidine metabolism_Homo sapiens_hsa002401.09896857
56Cell cycle_Homo sapiens_hsa041101.09871209
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09792270
58Fanconi anemia pathway_Homo sapiens_hsa034601.05917032
59Graft-versus-host disease_Homo sapiens_hsa053321.05840508
60Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.04425095
61Autoimmune thyroid disease_Homo sapiens_hsa053201.04001661
62Leukocyte transendothelial migration_Homo sapiens_hsa046701.03466609
63p53 signaling pathway_Homo sapiens_hsa041151.02656602
64Basal cell carcinoma_Homo sapiens_hsa052171.01452204
65Apoptosis_Homo sapiens_hsa042101.00903521
66Mismatch repair_Homo sapiens_hsa034300.98897067
67Prostate cancer_Homo sapiens_hsa052150.98529519
68Viral carcinogenesis_Homo sapiens_hsa052030.97716401
69Viral myocarditis_Homo sapiens_hsa054160.95844737
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.95578799
71Platelet activation_Homo sapiens_hsa046110.95150947
72Non-small cell lung cancer_Homo sapiens_hsa052230.94987413
73Olfactory transduction_Homo sapiens_hsa047400.93255201
74Linoleic acid metabolism_Homo sapiens_hsa005910.92881683
75Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.92590116
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.90925652
77Tuberculosis_Homo sapiens_hsa051520.90191304
78DNA replication_Homo sapiens_hsa030300.89920378
79Colorectal cancer_Homo sapiens_hsa052100.89196922
80Purine metabolism_Homo sapiens_hsa002300.86128180
81Base excision repair_Homo sapiens_hsa034100.85494440
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85301145
83Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.85180348
84RNA transport_Homo sapiens_hsa030130.84748449
85RNA degradation_Homo sapiens_hsa030180.83871645
86Prolactin signaling pathway_Homo sapiens_hsa049170.83729806
87Selenocompound metabolism_Homo sapiens_hsa004500.83073850
88Staphylococcus aureus infection_Homo sapiens_hsa051500.82508269
89Sulfur relay system_Homo sapiens_hsa041220.80482146
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76989381
91Epstein-Barr virus infection_Homo sapiens_hsa051690.75763767
92FoxO signaling pathway_Homo sapiens_hsa040680.74146017
93Shigellosis_Homo sapiens_hsa051310.71781440
94Hepatitis C_Homo sapiens_hsa051600.71618335
95Hedgehog signaling pathway_Homo sapiens_hsa043400.71037944
96Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70813563
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70613929
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70185103
99Regulation of autophagy_Homo sapiens_hsa041400.69943061
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67771988
101Pathways in cancer_Homo sapiens_hsa052000.67379851
102Proteoglycans in cancer_Homo sapiens_hsa052050.67181549
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67033082
104Pertussis_Homo sapiens_hsa051330.66466152
105Nitrogen metabolism_Homo sapiens_hsa009100.66272056
106Endometrial cancer_Homo sapiens_hsa052130.65228024
107Type II diabetes mellitus_Homo sapiens_hsa049300.65219110
108Malaria_Homo sapiens_hsa051440.63785009
109mTOR signaling pathway_Homo sapiens_hsa041500.63646597
110Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63552056
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.62738580
112Legionellosis_Homo sapiens_hsa051340.62538911
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61873976
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61508894
115Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60810198
116Thyroid cancer_Homo sapiens_hsa052160.59778946
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59592210
118Asthma_Homo sapiens_hsa053100.58399835
119Melanoma_Homo sapiens_hsa052180.57234838
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57068383
121Morphine addiction_Homo sapiens_hsa050320.56397387
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55439942
123Inositol phosphate metabolism_Homo sapiens_hsa005620.54762819
124One carbon pool by folate_Homo sapiens_hsa006700.54409326
125TGF-beta signaling pathway_Homo sapiens_hsa043500.54304859
126Rap1 signaling pathway_Homo sapiens_hsa040150.53424720
127Wnt signaling pathway_Homo sapiens_hsa043100.52989579
128Taste transduction_Homo sapiens_hsa047420.52359178
129MAPK signaling pathway_Homo sapiens_hsa040100.51900700
130Salmonella infection_Homo sapiens_hsa051320.50269195
131Type I diabetes mellitus_Homo sapiens_hsa049400.49726715
132Ether lipid metabolism_Homo sapiens_hsa005650.49304366
133Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48934117
134HIF-1 signaling pathway_Homo sapiens_hsa040660.48658660
135Glioma_Homo sapiens_hsa052140.48347623
136African trypanosomiasis_Homo sapiens_hsa051430.48104087
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47703878
138Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.39172595
139Cysteine and methionine metabolism_Homo sapiens_hsa002700.39074107
140Oocyte meiosis_Homo sapiens_hsa041140.37702873
141Folate biosynthesis_Homo sapiens_hsa007900.37603653
142Maturity onset diabetes of the young_Homo sapiens_hsa049500.35261857
143Dorso-ventral axis formation_Homo sapiens_hsa043200.34998741
144Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33929520
145Cholinergic synapse_Homo sapiens_hsa047250.32099705
146Serotonergic synapse_Homo sapiens_hsa047260.30826823
147Cocaine addiction_Homo sapiens_hsa050300.27506406
148Hippo signaling pathway_Homo sapiens_hsa043900.26896987
149Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.21757362
150Circadian rhythm_Homo sapiens_hsa047100.20074661
151Glutamatergic synapse_Homo sapiens_hsa047240.18704881

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