Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 4.84667626 |
2 | nuclear pore organization (GO:0006999) | 4.75835817 |
3 | DNA unwinding involved in DNA replication (GO:0006268) | 4.52563381 |
4 | protein localization to kinetochore (GO:0034501) | 4.47630806 |
5 | kinetochore organization (GO:0051383) | 4.40889556 |
6 | establishment of integrated proviral latency (GO:0075713) | 4.28386069 |
7 | mitotic sister chromatid cohesion (GO:0007064) | 4.28104813 |
8 | mitotic metaphase plate congression (GO:0007080) | 4.24655627 |
9 | CENP-A containing nucleosome assembly (GO:0034080) | 4.07789478 |
10 | chromatin remodeling at centromere (GO:0031055) | 4.06799357 |
11 | mitotic chromosome condensation (GO:0007076) | 3.97983835 |
12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.94044307 |
13 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.91432414 |
14 | protein localization to chromosome, centromeric region (GO:0071459) | 3.90615420 |
15 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.89171309 |
16 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.89171309 |
17 | metaphase plate congression (GO:0051310) | 3.88404375 |
18 | mitotic nuclear envelope disassembly (GO:0007077) | 3.83478657 |
19 | DNA replication initiation (GO:0006270) | 3.83462025 |
20 | pore complex assembly (GO:0046931) | 3.82176647 |
21 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.80646672 |
22 | DNA replication-independent nucleosome organization (GO:0034724) | 3.80646672 |
23 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.76654579 |
24 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.76654579 |
25 | DNA strand elongation (GO:0022616) | 3.75053847 |
26 | DNA replication checkpoint (GO:0000076) | 3.73584546 |
27 | DNA ligation (GO:0006266) | 3.72735663 |
28 | non-recombinational repair (GO:0000726) | 3.70892767 |
29 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.70892767 |
30 | mitotic recombination (GO:0006312) | 3.66552136 |
31 | DNA double-strand break processing (GO:0000729) | 3.65326032 |
32 | kinetochore assembly (GO:0051382) | 3.65298611 |
33 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.63952391 |
34 | IMP biosynthetic process (GO:0006188) | 3.63418092 |
35 | synapsis (GO:0007129) | 3.62402381 |
36 | sister chromatid segregation (GO:0000819) | 3.61911136 |
37 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.60583015 |
38 | telomere maintenance via recombination (GO:0000722) | 3.57296263 |
39 | regulation of spindle organization (GO:0090224) | 3.56641889 |
40 | nuclear envelope disassembly (GO:0051081) | 3.55790222 |
41 | membrane disassembly (GO:0030397) | 3.55790222 |
42 | histone exchange (GO:0043486) | 3.50880494 |
43 | mitotic sister chromatid segregation (GO:0000070) | 3.48578741 |
44 | positive regulation of chromosome segregation (GO:0051984) | 3.48473014 |
45 | establishment of chromosome localization (GO:0051303) | 3.47557932 |
46 | meiotic chromosome segregation (GO:0045132) | 3.44302901 |
47 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.43855173 |
48 | replication fork processing (GO:0031297) | 3.39195627 |
49 | DNA topological change (GO:0006265) | 3.36291826 |
50 | maturation of SSU-rRNA (GO:0030490) | 3.36253009 |
51 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.35303209 |
52 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.35303209 |
53 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.35303209 |
54 | nucleobase biosynthetic process (GO:0046112) | 3.34209143 |
55 | proteasome assembly (GO:0043248) | 3.33324605 |
56 | formation of translation preinitiation complex (GO:0001731) | 3.27673920 |
57 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.26826765 |
58 | DNA duplex unwinding (GO:0032508) | 3.26577850 |
59 | DNA geometric change (GO:0032392) | 3.26351451 |
60 | centriole replication (GO:0007099) | 3.24304813 |
61 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.22972071 |
62 | ribosomal small subunit assembly (GO:0000028) | 3.19993287 |
63 | chromatin assembly or disassembly (GO:0006333) | 3.18663725 |
64 | resolution of meiotic recombination intermediates (GO:0000712) | 3.17824927 |
65 | purine nucleobase biosynthetic process (GO:0009113) | 3.17243004 |
66 | IMP metabolic process (GO:0046040) | 3.16479615 |
67 | negative regulation of DNA recombination (GO:0045910) | 3.15129284 |
68 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.14800485 |
69 | regulation of mitotic spindle organization (GO:0060236) | 3.13379578 |
70 | histone mRNA metabolic process (GO:0008334) | 3.12924071 |
71 | establishment of viral latency (GO:0019043) | 3.11974770 |
72 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.11793433 |
73 | ATP-dependent chromatin remodeling (GO:0043044) | 3.10905114 |
74 | negative regulation of mitosis (GO:0045839) | 3.10055322 |
75 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.07784373 |
76 | telomere maintenance via telomere lengthening (GO:0010833) | 3.06771577 |
77 | regulation of RNA export from nucleus (GO:0046831) | 3.06421081 |
78 | spindle checkpoint (GO:0031577) | 3.05667481 |
79 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.04850374 |
80 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.03896481 |
81 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.03067503 |
82 | pre-miRNA processing (GO:0031054) | 3.02956348 |
83 | regulation of centrosome cycle (GO:0046605) | 3.02905029 |
84 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.02643486 |
85 | ribosome assembly (GO:0042255) | 3.01544919 |
86 | negative regulation of DNA repair (GO:0045738) | 3.00106894 |
87 | DNA synthesis involved in DNA repair (GO:0000731) | 2.99245447 |
88 | regulation of centriole replication (GO:0046599) | 2.98693040 |
89 | regulation of sister chromatid cohesion (GO:0007063) | 2.98512449 |
90 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.98094772 |
91 | DNA damage response, detection of DNA damage (GO:0042769) | 2.96851924 |
92 | regulation of chromosome segregation (GO:0051983) | 2.96473073 |
93 | regulation of DNA endoreduplication (GO:0032875) | 2.95909869 |
94 | response to X-ray (GO:0010165) | 2.93492278 |
95 | termination of RNA polymerase II transcription (GO:0006369) | 2.93207227 |
96 | chromosome segregation (GO:0007059) | 2.92984844 |
97 | DNA conformation change (GO:0071103) | 2.92421884 |
98 | regulation of histone H3-K9 methylation (GO:0051570) | 2.91894926 |
99 | ribosomal large subunit biogenesis (GO:0042273) | 2.89668291 |
100 | mismatch repair (GO:0006298) | 2.88599527 |
101 | protein localization to chromosome (GO:0034502) | 2.87832393 |
102 | protein K6-linked ubiquitination (GO:0085020) | 2.86741459 |
103 | viral mRNA export from host cell nucleus (GO:0046784) | 2.86167491 |
104 | spindle assembly checkpoint (GO:0071173) | 2.84756357 |
105 | mitotic spindle checkpoint (GO:0071174) | 2.83032196 |
106 | chromosome condensation (GO:0030261) | 2.81287604 |
107 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.81280659 |
108 | negative regulation of sister chromatid segregation (GO:0033046) | 2.81280659 |
109 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.81280659 |
110 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.81280659 |
111 | negative regulation of chromosome segregation (GO:0051985) | 2.81121142 |
112 | regulation of helicase activity (GO:0051095) | 2.80633594 |
113 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.79945064 |
114 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.79945064 |
115 | regulation of sister chromatid segregation (GO:0033045) | 2.79945064 |
116 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.78802961 |
117 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.77564647 |
118 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.77436697 |
119 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.77436697 |
120 | telomere maintenance (GO:0000723) | 2.75352667 |
121 | chromatin assembly (GO:0031497) | 2.75271985 |
122 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.73231343 |
123 | mitotic spindle assembly checkpoint (GO:0007094) | 2.73199268 |
124 | telomere organization (GO:0032200) | 2.72747763 |
125 | mitotic G2/M transition checkpoint (GO:0044818) | 2.71524965 |
126 | RNA splicing, via transesterification reactions (GO:0000375) | 2.70983497 |
127 | nuclear envelope organization (GO:0006998) | 2.70514537 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.98850836 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.39039660 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.77744657 |
4 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.55053611 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.87201543 |
6 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.59609913 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.58512583 |
8 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.58065199 |
9 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.57770478 |
10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.56404090 |
11 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.52950896 |
12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.48900190 |
13 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.37932397 |
14 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.30588742 |
15 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.25783080 |
16 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.19954208 |
17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.17485426 |
18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.12097122 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.11066583 |
20 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.10105463 |
21 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.04691338 |
22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04536194 |
23 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.03924155 |
24 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.2860942 |
25 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.98180851 |
26 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.96237697 |
27 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.95623608 |
28 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.94852005 |
29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.86945823 |
30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.81228052 |
31 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.80666360 |
32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.80204732 |
33 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.77868019 |
34 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.76797576 |
35 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.74364017 |
36 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.65885892 |
37 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.64663227 |
38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.63120652 |
39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.62347019 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.61318152 |
41 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.60819802 |
42 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.58283731 |
43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.57708646 |
44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.56988491 |
45 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.53852009 |
46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.51522835 |
47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.46173698 |
48 | MYC_22102868_ChIP-Seq_BL_Human | 1.46152890 |
49 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.39141706 |
50 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.38025205 |
51 | * POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.37660177 |
52 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.37590604 |
53 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.37057919 |
54 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.37015847 |
55 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36834195 |
56 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.35658863 |
57 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.35582207 |
58 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.32988296 |
59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.31650171 |
60 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.30573747 |
61 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.27912625 |
62 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.26300792 |
63 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.23800994 |
64 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22199486 |
65 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.21575786 |
66 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.19571261 |
67 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.19042836 |
68 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.19042836 |
69 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.19042836 |
70 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.15087114 |
71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.13469087 |
72 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.12644662 |
73 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.11666459 |
74 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.11191453 |
75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.09861630 |
76 | VDR_22108803_ChIP-Seq_LS180_Human | 1.07234444 |
77 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.05955862 |
78 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.05863735 |
79 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.03927630 |
80 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.02987987 |
81 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.02932010 |
82 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.02756878 |
83 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00872220 |
84 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.99636785 |
85 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97542447 |
86 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.97532215 |
87 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.96639582 |
88 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.96317595 |
89 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.96197764 |
90 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.95924240 |
91 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.95414955 |
92 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.93666952 |
93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.92719746 |
94 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.90567768 |
95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89809105 |
96 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89724509 |
97 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.89541603 |
98 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.88893699 |
99 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.88754374 |
100 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.88422717 |
101 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.88239721 |
102 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.87680479 |
103 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.86856164 |
104 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.85465163 |
105 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.85438756 |
106 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83844586 |
107 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.83397959 |
108 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.83305053 |
109 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.82561205 |
110 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.82030258 |
111 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.81899900 |
112 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.80779732 |
113 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.79365840 |
114 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.79326327 |
115 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.77842219 |
116 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.76344421 |
117 | MYB_26560356_Chip-Seq_TH1_Human | 0.75499976 |
118 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.75221275 |
119 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.74472530 |
120 | MYB_26560356_Chip-Seq_TH2_Human | 0.74386614 |
121 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.73644819 |
122 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.73469901 |
123 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.73122075 |
124 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.72877160 |
125 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.70695093 |
126 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.70680476 |
127 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.70258584 |
128 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.69478422 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.04171513 |
2 | MP0003693_abnormal_embryo_hatching | 4.03563997 |
3 | MP0008057_abnormal_DNA_replication | 3.85776986 |
4 | MP0003111_abnormal_nucleus_morphology | 3.48049057 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.42517857 |
6 | MP0003077_abnormal_cell_cycle | 3.39134597 |
7 | MP0006292_abnormal_olfactory_placode | 2.78374920 |
8 | MP0008007_abnormal_cellular_replicative | 2.74770694 |
9 | MP0008058_abnormal_DNA_repair | 2.66167727 |
10 | MP0010352_gastrointestinal_tract_polyps | 2.47266227 |
11 | MP0010307_abnormal_tumor_latency | 2.21531668 |
12 | MP0008932_abnormal_embryonic_tissue | 2.19231000 |
13 | MP0003123_paternal_imprinting | 2.11514310 |
14 | MP0002396_abnormal_hematopoietic_system | 2.06693701 |
15 | MP0000350_abnormal_cell_proliferation | 2.02182538 |
16 | MP0008877_abnormal_DNA_methylation | 2.00641765 |
17 | MP0001730_embryonic_growth_arrest | 1.98154660 |
18 | MP0005076_abnormal_cell_differentiation | 1.80472331 |
19 | MP0004808_abnormal_hematopoietic_stem | 1.65419076 |
20 | MP0005380_embryogenesis_phenotype | 1.60682183 |
21 | MP0001672_abnormal_embryogenesis/_devel | 1.60682183 |
22 | MP0003890_abnormal_embryonic-extraembry | 1.57852333 |
23 | MP0003121_genomic_imprinting | 1.56320905 |
24 | MP0001697_abnormal_embryo_size | 1.52687781 |
25 | MP0010030_abnormal_orbit_morphology | 1.51914476 |
26 | MP0004197_abnormal_fetal_growth/weight/ | 1.49521072 |
27 | MP0000490_abnormal_crypts_of | 1.49187422 |
28 | MP0003984_embryonic_growth_retardation | 1.48232457 |
29 | MP0002088_abnormal_embryonic_growth/wei | 1.45552907 |
30 | MP0002084_abnormal_developmental_patter | 1.39389249 |
31 | MP0002085_abnormal_embryonic_tissue | 1.37890380 |
32 | MP0008789_abnormal_olfactory_epithelium | 1.36806244 |
33 | MP0003567_abnormal_fetal_cardiomyocyte | 1.36703519 |
34 | MP0001293_anophthalmia | 1.35876257 |
35 | MP0008995_early_reproductive_senescence | 1.34420302 |
36 | MP0002086_abnormal_extraembryonic_tissu | 1.33755556 |
37 | MP0003786_premature_aging | 1.30429813 |
38 | MP0009053_abnormal_anal_canal | 1.30247980 |
39 | MP0000537_abnormal_urethra_morphology | 1.30050764 |
40 | MP0002080_prenatal_lethality | 1.27399907 |
41 | MP0001188_hyperpigmentation | 1.27316311 |
42 | MP0002233_abnormal_nose_morphology | 1.25285056 |
43 | MP0003937_abnormal_limbs/digits/tail_de | 1.22961052 |
44 | MP0002009_preneoplasia | 1.22874367 |
45 | MP0002019_abnormal_tumor_incidence | 1.18189418 |
46 | MP0005499_abnormal_olfactory_system | 1.17628376 |
47 | MP0005394_taste/olfaction_phenotype | 1.17628376 |
48 | MP0006072_abnormal_retinal_apoptosis | 1.17463495 |
49 | MP0006035_abnormal_mitochondrial_morpho | 1.17078394 |
50 | MP0003763_abnormal_thymus_physiology | 1.15983869 |
51 | MP0000313_abnormal_cell_death | 1.15698211 |
52 | MP0002166_altered_tumor_susceptibility | 1.12724176 |
53 | MP0003705_abnormal_hypodermis_morpholog | 1.09974452 |
54 | MP0003315_abnormal_perineum_morphology | 1.09337541 |
55 | MP0001529_abnormal_vocalization | 1.08501618 |
56 | MP0002006_tumorigenesis | 1.07192714 |
57 | MP0002102_abnormal_ear_morphology | 1.06690325 |
58 | MP0001545_abnormal_hematopoietic_system | 1.04666229 |
59 | MP0005397_hematopoietic_system_phenotyp | 1.04666229 |
60 | MP0000703_abnormal_thymus_morphology | 1.02751617 |
61 | MP0000569_abnormal_digit_pigmentation | 1.02123738 |
62 | MP0003941_abnormal_skin_development | 1.01949715 |
63 | MP0006054_spinal_hemorrhage | 1.01584471 |
64 | MP0000647_abnormal_sebaceous_gland | 1.00894935 |
65 | MP0002398_abnormal_bone_marrow | 1.00618030 |
66 | MP0009333_abnormal_splenocyte_physiolog | 0.96450234 |
67 | MP0002210_abnormal_sex_determination | 0.96095013 |
68 | MP0009703_decreased_birth_body | 0.93608590 |
69 | MP0003718_maternal_effect | 0.93418577 |
70 | MP0003787_abnormal_imprinting | 0.93115682 |
71 | MP0003221_abnormal_cardiomyocyte_apopto | 0.92056734 |
72 | MP0000358_abnormal_cell_content/ | 0.91146823 |
73 | MP0002160_abnormal_reproductive_system | 0.91136821 |
74 | MP0002092_abnormal_eye_morphology | 0.90459343 |
75 | MP0002111_abnormal_tail_morphology | 0.89520516 |
76 | MP0009672_abnormal_birth_weight | 0.88965091 |
77 | MP0000432_abnormal_head_morphology | 0.88930759 |
78 | MP0002722_abnormal_immune_system | 0.86922668 |
79 | MP0001915_intracranial_hemorrhage | 0.86844894 |
80 | MP0002938_white_spotting | 0.86082906 |
81 | MP0001286_abnormal_eye_development | 0.85663100 |
82 | MP0003136_yellow_coat_color | 0.85338399 |
83 | MP0002751_abnormal_autonomic_nervous | 0.85094632 |
84 | MP0005395_other_phenotype | 0.84936064 |
85 | MP0000516_abnormal_urinary_system | 0.83680774 |
86 | MP0005367_renal/urinary_system_phenotyp | 0.83680774 |
87 | MP0001145_abnormal_male_reproductive | 0.83404313 |
88 | MP0004264_abnormal_extraembryonic_tissu | 0.82783141 |
89 | MP0000689_abnormal_spleen_morphology | 0.82242713 |
90 | MP0000858_altered_metastatic_potential | 0.81644959 |
91 | MP0000428_abnormal_craniofacial_morphol | 0.81201083 |
92 | MP0003861_abnormal_nervous_system | 0.80678088 |
93 | MP0005023_abnormal_wound_healing | 0.80024005 |
94 | MP0009278_abnormal_bone_marrow | 0.79481822 |
95 | MP0000733_abnormal_muscle_development | 0.78747254 |
96 | MP0001835_abnormal_antigen_presentation | 0.78383896 |
97 | MP0002234_abnormal_pharynx_morphology | 0.78335476 |
98 | MP0003448_altered_tumor_morphology | 0.78021184 |
99 | MP0001119_abnormal_female_reproductive | 0.77257277 |
100 | MP0000372_irregular_coat_pigmentation | 0.76785994 |
101 | MP0003566_abnormal_cell_adhesion | 0.75902066 |
102 | MP0005391_vision/eye_phenotype | 0.75336427 |
103 | MP0003385_abnormal_body_wall | 0.75000066 |
104 | MP0001929_abnormal_gametogenesis | 0.74838947 |
105 | MP0002429_abnormal_blood_cell | 0.73343003 |
106 | MP0003186_abnormal_redox_activity | 0.73278065 |
107 | MP0000653_abnormal_sex_gland | 0.72654082 |
108 | MP0005408_hypopigmentation | 0.72310065 |
109 | MP0003699_abnormal_female_reproductive | 0.72193693 |
110 | MP0003300_gastrointestinal_ulcer | 0.71981163 |
111 | MP0009697_abnormal_copulation | 0.71242797 |
112 | MP0003943_abnormal_hepatobiliary_system | 0.71206101 |
113 | MP0003698_abnormal_male_reproductive | 0.71041791 |
114 | MP0003935_abnormal_craniofacial_develop | 0.70689508 |
115 | MP0002095_abnormal_skin_pigmentation | 0.70374432 |
116 | MP0000716_abnormal_immune_system | 0.69970746 |
117 | MP0003755_abnormal_palate_morphology | 0.69959896 |
118 | MP0002877_abnormal_melanocyte_morpholog | 0.68838600 |
119 | MP0000049_abnormal_middle_ear | 0.68717964 |
120 | MP0000627_abnormal_mammary_gland | 0.68467620 |
121 | MP0005187_abnormal_penis_morphology | 0.67696074 |
122 | MP0001800_abnormal_humoral_immune | 0.67250065 |
123 | MP0005621_abnormal_cell_physiology | 0.66864799 |
124 | MP0002697_abnormal_eye_size | 0.65661455 |
125 | MP0005389_reproductive_system_phenotype | 0.65151952 |
126 | MP0002452_abnormal_antigen_presenting | 0.64960251 |
127 | MP0001177_atelectasis | 0.64704210 |
128 | MP0002161_abnormal_fertility/fecundity | 0.64393799 |
129 | MP0005384_cellular_phenotype | 0.63889423 |
130 | MP0003119_abnormal_digestive_system | 0.63820217 |
131 | MP0003115_abnormal_respiratory_system | 0.62207018 |
132 | MP0006036_abnormal_mitochondrial_physio | 0.61084990 |
133 | MP0001299_abnormal_eye_distance/ | 0.60095321 |
134 | MP0000427_abnormal_hair_cycle | 0.59170726 |
135 | MP0000383_abnormal_hair_follicle | 0.58835758 |
136 | MP0000631_abnormal_neuroendocrine_gland | 0.57290848 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromsome breakage (HP:0040012) | 4.10747899 |
2 | Birth length less than 3rd percentile (HP:0003561) | 3.95506775 |
3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.75351901 |
4 | Volvulus (HP:0002580) | 3.61249196 |
5 | Abnormality of chromosome stability (HP:0003220) | 3.28656896 |
6 | Colon cancer (HP:0003003) | 3.26456473 |
7 | Reticulocytopenia (HP:0001896) | 3.00838359 |
8 | Meckel diverticulum (HP:0002245) | 2.90882005 |
9 | Abnormality of the preputium (HP:0100587) | 2.84694219 |
10 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.81967989 |
11 | Medulloblastoma (HP:0002885) | 2.81239283 |
12 | Ectopic kidney (HP:0000086) | 2.78315538 |
13 | Abnormality of the ileum (HP:0001549) | 2.76713364 |
14 | Patellar aplasia (HP:0006443) | 2.73163013 |
15 | Selective tooth agenesis (HP:0001592) | 2.71289601 |
16 | Abnormality of the anterior horn cell (HP:0006802) | 2.63706419 |
17 | Degeneration of anterior horn cells (HP:0002398) | 2.63706419 |
18 | Cortical dysplasia (HP:0002539) | 2.63469389 |
19 | Breast hypoplasia (HP:0003187) | 2.61755971 |
20 | Deviation of the thumb (HP:0009603) | 2.58517810 |
21 | 11 pairs of ribs (HP:0000878) | 2.58414113 |
22 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.58173407 |
23 | Myelodysplasia (HP:0002863) | 2.55445235 |
24 | Proximal placement of thumb (HP:0009623) | 2.54865351 |
25 | Abnormality of methionine metabolism (HP:0010901) | 2.50626048 |
26 | Impulsivity (HP:0100710) | 2.42789285 |
27 | Short 4th metacarpal (HP:0010044) | 2.38556575 |
28 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.38556575 |
29 | Small intestinal stenosis (HP:0012848) | 2.36836459 |
30 | Duodenal stenosis (HP:0100867) | 2.36836459 |
31 | Gonadotropin excess (HP:0000837) | 2.35411144 |
32 | Increased nuchal translucency (HP:0010880) | 2.34130307 |
33 | Septo-optic dysplasia (HP:0100842) | 2.27393115 |
34 | Biliary tract neoplasm (HP:0100574) | 2.24776610 |
35 | Absent radius (HP:0003974) | 2.24667087 |
36 | Multiple enchondromatosis (HP:0005701) | 2.23661123 |
37 | Acute myeloid leukemia (HP:0004808) | 2.22383341 |
38 | Atresia of the external auditory canal (HP:0000413) | 2.21800986 |
39 | Abnormality of the fingertips (HP:0001211) | 2.19066707 |
40 | Abnormal lung lobation (HP:0002101) | 2.18899109 |
41 | Neoplasm of the pancreas (HP:0002894) | 2.18337247 |
42 | Aplastic anemia (HP:0001915) | 2.18067137 |
43 | Increased hepatocellular lipid droplets (HP:0006565) | 2.14941594 |
44 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.14221639 |
45 | Bifid tongue (HP:0010297) | 2.13739587 |
46 | Sloping forehead (HP:0000340) | 2.12372586 |
47 | Absent thumb (HP:0009777) | 2.12332908 |
48 | Oral leukoplakia (HP:0002745) | 2.09372931 |
49 | Rhabdomyosarcoma (HP:0002859) | 2.08864413 |
50 | Long eyelashes (HP:0000527) | 2.08574804 |
51 | Papillary thyroid carcinoma (HP:0002895) | 2.08490333 |
52 | Abnormality of the labia minora (HP:0012880) | 2.07806959 |
53 | Absent forearm bone (HP:0003953) | 2.06929624 |
54 | Aplasia involving forearm bones (HP:0009822) | 2.06929624 |
55 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.05586387 |
56 | Intestinal atresia (HP:0011100) | 2.04189437 |
57 | Missing ribs (HP:0000921) | 2.02400171 |
58 | Embryonal renal neoplasm (HP:0011794) | 2.02198136 |
59 | Oligodactyly (hands) (HP:0001180) | 2.01866565 |
60 | Microvesicular hepatic steatosis (HP:0001414) | 2.01300137 |
61 | Short thumb (HP:0009778) | 2.00385026 |
62 | Abnormality of the duodenum (HP:0002246) | 1.99673407 |
63 | Agnosia (HP:0010524) | 1.99442753 |
64 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.97401700 |
65 | Glioma (HP:0009733) | 1.97193612 |
66 | Ependymoma (HP:0002888) | 1.96988046 |
67 | Abnormality of the septum pellucidum (HP:0007375) | 1.94658152 |
68 | Deep philtrum (HP:0002002) | 1.93912270 |
69 | Macrocytic anemia (HP:0001972) | 1.93843588 |
70 | Abnormality of the carotid arteries (HP:0005344) | 1.92024890 |
71 | Blepharitis (HP:0000498) | 1.90255777 |
72 | Megaloblastic anemia (HP:0001889) | 1.90076735 |
73 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.89620838 |
74 | Bone marrow hypocellularity (HP:0005528) | 1.88796490 |
75 | Methylmalonic acidemia (HP:0002912) | 1.88400733 |
76 | Choanal atresia (HP:0000453) | 1.87857030 |
77 | Homocystinuria (HP:0002156) | 1.87581236 |
78 | Abnormality of homocysteine metabolism (HP:0010919) | 1.87581236 |
79 | Neoplasm of the colon (HP:0100273) | 1.87500456 |
80 | Premature graying of hair (HP:0002216) | 1.85022386 |
81 | Clubbing of toes (HP:0100760) | 1.84211751 |
82 | Cutaneous melanoma (HP:0012056) | 1.84111425 |
83 | Lipid accumulation in hepatocytes (HP:0006561) | 1.83893668 |
84 | Carpal bone hypoplasia (HP:0001498) | 1.83301981 |
85 | Triphalangeal thumb (HP:0001199) | 1.82944296 |
86 | Tracheoesophageal fistula (HP:0002575) | 1.82242006 |
87 | Short middle phalanx of the 5th finger (HP:0004220) | 1.81230596 |
88 | High pitched voice (HP:0001620) | 1.80171384 |
89 | Thrombocytosis (HP:0001894) | 1.79112666 |
90 | Facial hemangioma (HP:0000329) | 1.78925204 |
91 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.78836785 |
92 | Gastrointestinal carcinoma (HP:0002672) | 1.78836785 |
93 | Abnormality of serum amino acid levels (HP:0003112) | 1.77719971 |
94 | Embryonal neoplasm (HP:0002898) | 1.76984186 |
95 | Prominent nose (HP:0000448) | 1.76488814 |
96 | Lymphoma (HP:0002665) | 1.76016713 |
97 | Absent septum pellucidum (HP:0001331) | 1.75957465 |
98 | Supernumerary spleens (HP:0009799) | 1.75945935 |
99 | Stenosis of the external auditory canal (HP:0000402) | 1.75322721 |
100 | Cafe-au-lait spot (HP:0000957) | 1.73779229 |
101 | Rough bone trabeculation (HP:0100670) | 1.73205694 |
102 | Increased serum pyruvate (HP:0003542) | 1.72244235 |
103 | Spinal cord lesions (HP:0100561) | 1.71899126 |
104 | Syringomyelia (HP:0003396) | 1.71899126 |
105 | Premature ovarian failure (HP:0008209) | 1.71871803 |
106 | Gastrointestinal atresia (HP:0002589) | 1.71652898 |
107 | Median cleft lip (HP:0000161) | 1.71579982 |
108 | Abnormal number of incisors (HP:0011064) | 1.71325470 |
109 | Abnormal biliary tract morphology (HP:0012440) | 1.71157514 |
110 | Abnormality of the calcaneus (HP:0008364) | 1.70040803 |
111 | Neoplasm of the small intestine (HP:0100833) | 1.69338645 |
112 | Acute encephalopathy (HP:0006846) | 1.68822143 |
113 | Facial cleft (HP:0002006) | 1.68247658 |
114 | Abnormal hair whorl (HP:0010721) | 1.67871143 |
115 | Overlapping toe (HP:0001845) | 1.67522950 |
116 | Basal cell carcinoma (HP:0002671) | 1.67438361 |
117 | Squamous cell carcinoma (HP:0002860) | 1.65940943 |
118 | Hyperglycinemia (HP:0002154) | 1.65663439 |
119 | Acute necrotizing encephalopathy (HP:0006965) | 1.65238905 |
120 | Capillary hemangiomas (HP:0005306) | 1.64404283 |
121 | Abnormality of the astrocytes (HP:0100707) | 1.64193417 |
122 | Astrocytoma (HP:0009592) | 1.64193417 |
123 | Esophageal atresia (HP:0002032) | 1.63178182 |
124 | Ovarian neoplasm (HP:0100615) | 1.62978289 |
125 | Arteriovenous malformation (HP:0100026) | 1.62565365 |
126 | Hypoplastic pelvis (HP:0008839) | 1.62513674 |
127 | Thyroid carcinoma (HP:0002890) | 1.62489841 |
128 | Amaurosis fugax (HP:0100576) | 1.61814258 |
129 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.61690979 |
130 | Rib fusion (HP:0000902) | 1.60993107 |
131 | Glossoptosis (HP:0000162) | 1.60710763 |
132 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.59404445 |
133 | Sandal gap (HP:0001852) | 1.59184651 |
134 | Pallor (HP:0000980) | 1.58818282 |
135 | Pelvic girdle muscle weakness (HP:0003749) | 1.58262415 |
136 | Horseshoe kidney (HP:0000085) | 1.57850166 |
137 | Progressive external ophthalmoplegia (HP:0000590) | 1.57131773 |
138 | Cellular immunodeficiency (HP:0005374) | 1.57127154 |
139 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.57115493 |
140 | Small hand (HP:0200055) | 1.56372269 |
141 | Abdominal situs inversus (HP:0003363) | 1.56329216 |
142 | Abnormality of abdominal situs (HP:0011620) | 1.56329216 |
143 | Supernumerary ribs (HP:0005815) | 1.56305986 |
144 | Optic nerve coloboma (HP:0000588) | 1.56187010 |
145 | Cleft eyelid (HP:0000625) | 1.56086182 |
146 | Cutis marmorata (HP:0000965) | 1.56030487 |
147 | Abnormality of the pons (HP:0007361) | 1.55761095 |
148 | Clitoromegaly (HP:0000057) | 1.55358646 |
149 | Hypoplasia of the radius (HP:0002984) | 1.55191782 |
150 | Postnatal microcephaly (HP:0005484) | 1.54872668 |
151 | Preaxial hand polydactyly (HP:0001177) | 1.53900227 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.52479776 |
2 | WEE1 | 3.22174285 |
3 | SRPK1 | 2.99920341 |
4 | NEK2 | 2.85215946 |
5 | EIF2AK1 | 2.61268051 |
6 | BUB1 | 2.60365740 |
7 | MKNK1 | 2.49839212 |
8 | TRIM28 | 2.44139592 |
9 | BRSK2 | 2.37899453 |
10 | PLK4 | 2.28993688 |
11 | CDK12 | 2.27422512 |
12 | ACVR1B | 2.12043994 |
13 | TTK | 2.02467497 |
14 | TNIK | 1.91285060 |
15 | MKNK2 | 1.90984917 |
16 | PLK3 | 1.88187025 |
17 | PASK | 1.84745631 |
18 | AURKB | 1.80155106 |
19 | EIF2AK3 | 1.77143083 |
20 | PLK1 | 1.76694168 |
21 | ATR | 1.75172970 |
22 | TLK1 | 1.72303966 |
23 | RPS6KA4 | 1.70861593 |
24 | STK10 | 1.68584451 |
25 | TSSK6 | 1.60872952 |
26 | NEK1 | 1.59704791 |
27 | NUAK1 | 1.59692653 |
28 | VRK1 | 1.51595057 |
29 | CDK7 | 1.49084261 |
30 | BMPR1B | 1.47852391 |
31 | VRK2 | 1.47360699 |
32 | ZAK | 1.46978914 |
33 | RPS6KB2 | 1.45220524 |
34 | NME2 | 1.45211248 |
35 | PBK | 1.44721989 |
36 | CHEK2 | 1.41235220 |
37 | WNK3 | 1.38696778 |
38 | BCR | 1.38222384 |
39 | STK4 | 1.35953204 |
40 | BRD4 | 1.35665870 |
41 | CHEK1 | 1.35182269 |
42 | TAF1 | 1.31919617 |
43 | MAP3K8 | 1.31566878 |
44 | DYRK3 | 1.30059636 |
45 | CDK6 | 1.28815946 |
46 | NME1 | 1.28380874 |
47 | STK3 | 1.26466560 |
48 | TESK2 | 1.22762395 |
49 | STK16 | 1.21568913 |
50 | CDK4 | 1.21233624 |
51 | ATM | 1.15025289 |
52 | NEK9 | 1.14262411 |
53 | LATS1 | 1.10270051 |
54 | PIM1 | 1.06762970 |
55 | EIF2AK2 | 1.06568772 |
56 | TGFBR1 | 1.05218415 |
57 | BRSK1 | 0.98304503 |
58 | MELK | 0.97876913 |
59 | EEF2K | 0.97813647 |
60 | SCYL2 | 0.87937888 |
61 | MST4 | 0.87757232 |
62 | EPHA2 | 0.86929620 |
63 | CDK2 | 0.86799258 |
64 | FRK | 0.82901359 |
65 | ERBB4 | 0.82801314 |
66 | MAP3K4 | 0.81509062 |
67 | AURKA | 0.75288432 |
68 | MAP4K1 | 0.74857079 |
69 | TEC | 0.74233536 |
70 | STK24 | 0.73846435 |
71 | CDK1 | 0.73324895 |
72 | FLT3 | 0.72001898 |
73 | JAK3 | 0.69942087 |
74 | CHUK | 0.68905605 |
75 | RPS6KA5 | 0.67519673 |
76 | MAP3K10 | 0.65404750 |
77 | PAK4 | 0.64780668 |
78 | LRRK2 | 0.63163382 |
79 | ERBB3 | 0.63118848 |
80 | CSNK2A2 | 0.63076418 |
81 | PLK2 | 0.62760809 |
82 | PDK2 | 0.62690524 |
83 | CLK1 | 0.62322660 |
84 | YES1 | 0.60312375 |
85 | NLK | 0.59640021 |
86 | ALK | 0.58127746 |
87 | CDK3 | 0.57207979 |
88 | CSNK2A1 | 0.56129487 |
89 | CSNK1G1 | 0.54556927 |
90 | IRAK4 | 0.54553318 |
91 | TRPM7 | 0.54145039 |
92 | CDK9 | 0.53991270 |
93 | TESK1 | 0.52861671 |
94 | BTK | 0.52279096 |
95 | CCNB1 | 0.51818676 |
96 | STK38L | 0.50055337 |
97 | STK39 | 0.49782878 |
98 | MTOR | 0.48750688 |
99 | TXK | 0.47220578 |
100 | FGFR1 | 0.44396794 |
101 | PRKDC | 0.43863530 |
102 | KSR1 | 0.42564852 |
103 | ITK | 0.41989243 |
104 | PNCK | 0.38413767 |
105 | MAPK14 | 0.37634234 |
106 | PAK2 | 0.36288563 |
107 | CDK8 | 0.35453071 |
108 | PKN2 | 0.35237361 |
109 | DYRK2 | 0.35106136 |
110 | CSNK1D | 0.34877013 |
111 | MAP3K14 | 0.34082242 |
112 | NEK6 | 0.33540294 |
113 | PIM2 | 0.32930243 |
114 | MAP2K7 | 0.32214779 |
115 | MARK3 | 0.31988944 |
116 | CSNK1E | 0.31918667 |
117 | AKT1 | 0.31863795 |
118 | OXSR1 | 0.30576836 |
119 | CSF1R | 0.30418596 |
120 | FGFR3 | 0.29617023 |
121 | IKBKB | 0.29218641 |
122 | PAK1 | 0.28206488 |
123 | PTK6 | 0.27998645 |
124 | CSNK1A1L | 0.27785943 |
125 | INSRR | 0.27507745 |
126 | PRKACB | 0.23654973 |
127 | SIK3 | 0.23629097 |
128 | CSNK1G2 | 0.23322153 |
129 | BRAF | 0.22770716 |
130 | CSNK1G3 | 0.20953446 |
131 | CAMK1G | 0.20584209 |
132 | AKT3 | 0.20384706 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.20857676 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.95895832 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.37067438 |
4 | * Spliceosome_Homo sapiens_hsa03040 | 3.08124769 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.03206817 |
6 | Cell cycle_Homo sapiens_hsa04110 | 2.95576445 |
7 | Homologous recombination_Homo sapiens_hsa03440 | 2.81115787 |
8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.74953714 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.58635505 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.54538577 |
11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.51394562 |
12 | Ribosome_Homo sapiens_hsa03010 | 2.42935033 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.40858738 |
14 | RNA polymerase_Homo sapiens_hsa03020 | 2.34420043 |
15 | Proteasome_Homo sapiens_hsa03050 | 2.11172641 |
16 | RNA degradation_Homo sapiens_hsa03018 | 1.95137164 |
17 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.92008845 |
18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.91913678 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.91578163 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.86293526 |
21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.83208905 |
22 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.79205194 |
23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.54709291 |
24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.42586689 |
25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.33615997 |
26 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.29935360 |
27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.29553203 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.29098789 |
29 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.27311464 |
30 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.15057398 |
31 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.14769577 |
32 | Parkinsons disease_Homo sapiens_hsa05012 | 1.10413986 |
33 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.06814265 |
34 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.06489329 |
35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.06310459 |
36 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.05234539 |
37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.04999096 |
38 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.04768692 |
39 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.03645506 |
40 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.03607411 |
41 | HTLV-I infection_Homo sapiens_hsa05166 | 0.94972075 |
42 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.94858620 |
43 | Legionellosis_Homo sapiens_hsa05134 | 0.94771462 |
44 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.93987972 |
45 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92017236 |
46 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.90790431 |
47 | Purine metabolism_Homo sapiens_hsa00230 | 0.89230267 |
48 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.88029866 |
49 | Measles_Homo sapiens_hsa05162 | 0.87474529 |
50 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.87317651 |
51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.83969547 |
52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.83593859 |
53 | Protein export_Homo sapiens_hsa03060 | 0.83574938 |
54 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.80715400 |
55 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80635566 |
56 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.79170237 |
57 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76768111 |
58 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.76294248 |
59 | Thyroid cancer_Homo sapiens_hsa05216 | 0.74413218 |
60 | Adherens junction_Homo sapiens_hsa04520 | 0.72989341 |
61 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.72366669 |
62 | Carbon metabolism_Homo sapiens_hsa01200 | 0.69159210 |
63 | Hepatitis B_Homo sapiens_hsa05161 | 0.68658786 |
64 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.67223604 |
65 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.66777046 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.66769472 |
67 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65646155 |
68 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.65606829 |
69 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.64690759 |
70 | Apoptosis_Homo sapiens_hsa04210 | 0.64274162 |
71 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.60216272 |
72 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.60004151 |
73 | Allograft rejection_Homo sapiens_hsa05330 | 0.59071212 |
74 | Prostate cancer_Homo sapiens_hsa05215 | 0.58760702 |
75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.56690564 |
76 | Colorectal cancer_Homo sapiens_hsa05210 | 0.56669985 |
77 | Alcoholism_Homo sapiens_hsa05034 | 0.56487778 |
78 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55001347 |
79 | Influenza A_Homo sapiens_hsa05164 | 0.54887422 |
80 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.53058168 |
81 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.52459876 |
82 | Leishmaniasis_Homo sapiens_hsa05140 | 0.52229616 |
83 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.51724763 |
84 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.51183389 |
85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50789022 |
86 | Shigellosis_Homo sapiens_hsa05131 | 0.49609505 |
87 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.47896161 |
88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47618401 |
89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.45338359 |
90 | Pathways in cancer_Homo sapiens_hsa05200 | 0.45179361 |
91 | Lysine degradation_Homo sapiens_hsa00310 | 0.44852714 |
92 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.44430969 |
93 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.43981957 |
94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.43016457 |
95 | Alzheimers disease_Homo sapiens_hsa05010 | 0.42378273 |
96 | Asthma_Homo sapiens_hsa05310 | 0.42203104 |
97 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.41546136 |
98 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.41032562 |
99 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.40991033 |
100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.40721483 |
101 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39688815 |
102 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39477013 |
103 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.38477185 |
104 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.37677222 |
105 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.36451827 |
106 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.35378026 |
107 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.34159409 |
108 | Bladder cancer_Homo sapiens_hsa05219 | 0.33589481 |
109 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.32722069 |
110 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32579280 |
111 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.31965646 |
112 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29936628 |
113 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.29796728 |
114 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.29110378 |
115 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.29062858 |
116 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28945615 |
117 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.28795878 |
118 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.28465614 |
119 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.27550419 |
120 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.26942684 |
121 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.26153678 |
122 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.26044982 |
123 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.25863849 |
124 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.25690138 |
125 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.25603916 |
126 | Melanoma_Homo sapiens_hsa05218 | 0.25521921 |
127 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.24183117 |
128 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.23842676 |
129 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22565162 |
130 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.22336585 |
131 | Circadian rhythm_Homo sapiens_hsa04710 | 0.18312761 |
132 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.18266427 |
133 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.15483696 |
134 | Peroxisome_Homo sapiens_hsa04146 | 0.14711894 |
135 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.14497169 |
136 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.12465642 |
137 | Tight junction_Homo sapiens_hsa04530 | 0.11809870 |
138 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.11192982 |
139 | Phototransduction_Homo sapiens_hsa04744 | 0.10693412 |
140 | Retinol metabolism_Homo sapiens_hsa00830 | 0.08433393 |
141 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.06870748 |
142 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.02811887 |