PRPF40A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.84667626
2nuclear pore organization (GO:0006999)4.75835817
3DNA unwinding involved in DNA replication (GO:0006268)4.52563381
4protein localization to kinetochore (GO:0034501)4.47630806
5kinetochore organization (GO:0051383)4.40889556
6establishment of integrated proviral latency (GO:0075713)4.28386069
7mitotic sister chromatid cohesion (GO:0007064)4.28104813
8mitotic metaphase plate congression (GO:0007080)4.24655627
9CENP-A containing nucleosome assembly (GO:0034080)4.07789478
10chromatin remodeling at centromere (GO:0031055)4.06799357
11mitotic chromosome condensation (GO:0007076)3.97983835
12regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.94044307
13DNA strand elongation involved in DNA replication (GO:0006271)3.91432414
14protein localization to chromosome, centromeric region (GO:0071459)3.90615420
15regulation of mitotic spindle checkpoint (GO:1903504)3.89171309
16regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.89171309
17metaphase plate congression (GO:0051310)3.88404375
18mitotic nuclear envelope disassembly (GO:0007077)3.83478657
19DNA replication initiation (GO:0006270)3.83462025
20pore complex assembly (GO:0046931)3.82176647
21DNA replication-independent nucleosome assembly (GO:0006336)3.80646672
22DNA replication-independent nucleosome organization (GO:0034724)3.80646672
23DNA replication-dependent nucleosome assembly (GO:0006335)3.76654579
24DNA replication-dependent nucleosome organization (GO:0034723)3.76654579
25DNA strand elongation (GO:0022616)3.75053847
26DNA replication checkpoint (GO:0000076)3.73584546
27DNA ligation (GO:0006266)3.72735663
28non-recombinational repair (GO:0000726)3.70892767
29double-strand break repair via nonhomologous end joining (GO:0006303)3.70892767
30mitotic recombination (GO:0006312)3.66552136
31DNA double-strand break processing (GO:0000729)3.65326032
32kinetochore assembly (GO:0051382)3.65298611
33attachment of spindle microtubules to kinetochore (GO:0008608)3.63952391
34IMP biosynthetic process (GO:0006188)3.63418092
35synapsis (GO:0007129)3.62402381
36sister chromatid segregation (GO:0000819)3.61911136
37telomere maintenance via semi-conservative replication (GO:0032201)3.60583015
38telomere maintenance via recombination (GO:0000722)3.57296263
39regulation of spindle organization (GO:0090224)3.56641889
40nuclear envelope disassembly (GO:0051081)3.55790222
41membrane disassembly (GO:0030397)3.55790222
42histone exchange (GO:0043486)3.50880494
43mitotic sister chromatid segregation (GO:0000070)3.48578741
44positive regulation of chromosome segregation (GO:0051984)3.48473014
45establishment of chromosome localization (GO:0051303)3.47557932
46meiotic chromosome segregation (GO:0045132)3.44302901
47folic acid-containing compound biosynthetic process (GO:0009396)3.43855173
48replication fork processing (GO:0031297)3.39195627
49DNA topological change (GO:0006265)3.36291826
50maturation of SSU-rRNA (GO:0030490)3.36253009
51positive regulation of mitotic sister chromatid separation (GO:1901970)3.35303209
52positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.35303209
53positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.35303209
54nucleobase biosynthetic process (GO:0046112)3.34209143
55proteasome assembly (GO:0043248)3.33324605
56formation of translation preinitiation complex (GO:0001731)3.27673920
57regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.26826765
58DNA duplex unwinding (GO:0032508)3.26577850
59DNA geometric change (GO:0032392)3.26351451
60centriole replication (GO:0007099)3.24304813
61DNA catabolic process, exonucleolytic (GO:0000738)3.22972071
62ribosomal small subunit assembly (GO:0000028)3.19993287
63chromatin assembly or disassembly (GO:0006333)3.18663725
64resolution of meiotic recombination intermediates (GO:0000712)3.17824927
65purine nucleobase biosynthetic process (GO:0009113)3.17243004
66IMP metabolic process (GO:0046040)3.16479615
67negative regulation of DNA recombination (GO:0045910)3.15129284
68regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.14800485
69regulation of mitotic spindle organization (GO:0060236)3.13379578
70histone mRNA metabolic process (GO:0008334)3.12924071
71establishment of viral latency (GO:0019043)3.11974770
72nucleotide-excision repair, DNA gap filling (GO:0006297)3.11793433
73ATP-dependent chromatin remodeling (GO:0043044)3.10905114
74negative regulation of mitosis (GO:0045839)3.10055322
75regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.07784373
76telomere maintenance via telomere lengthening (GO:0010833)3.06771577
77regulation of RNA export from nucleus (GO:0046831)3.06421081
78spindle checkpoint (GO:0031577)3.05667481
79regulation of mitotic metaphase/anaphase transition (GO:0030071)3.04850374
80anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.03896481
81negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.03067503
82pre-miRNA processing (GO:0031054)3.02956348
83regulation of centrosome cycle (GO:0046605)3.02905029
84maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.02643486
85ribosome assembly (GO:0042255)3.01544919
86negative regulation of DNA repair (GO:0045738)3.00106894
87DNA synthesis involved in DNA repair (GO:0000731)2.99245447
88regulation of centriole replication (GO:0046599)2.98693040
89regulation of sister chromatid cohesion (GO:0007063)2.98512449
90regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.98094772
91DNA damage response, detection of DNA damage (GO:0042769)2.96851924
92regulation of chromosome segregation (GO:0051983)2.96473073
93regulation of DNA endoreduplication (GO:0032875)2.95909869
94response to X-ray (GO:0010165)2.93492278
95termination of RNA polymerase II transcription (GO:0006369)2.93207227
96chromosome segregation (GO:0007059)2.92984844
97DNA conformation change (GO:0071103)2.92421884
98regulation of histone H3-K9 methylation (GO:0051570)2.91894926
99ribosomal large subunit biogenesis (GO:0042273)2.89668291
100mismatch repair (GO:0006298)2.88599527
101protein localization to chromosome (GO:0034502)2.87832393
102protein K6-linked ubiquitination (GO:0085020)2.86741459
103viral mRNA export from host cell nucleus (GO:0046784)2.86167491
104spindle assembly checkpoint (GO:0071173)2.84756357
105mitotic spindle checkpoint (GO:0071174)2.83032196
106chromosome condensation (GO:0030261)2.81287604
107negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.81280659
108negative regulation of sister chromatid segregation (GO:0033046)2.81280659
109negative regulation of mitotic sister chromatid separation (GO:2000816)2.81280659
110negative regulation of mitotic sister chromatid segregation (GO:0033048)2.81280659
111negative regulation of chromosome segregation (GO:0051985)2.81121142
112regulation of helicase activity (GO:0051095)2.80633594
113regulation of mitotic sister chromatid separation (GO:0010965)2.79945064
114regulation of mitotic sister chromatid segregation (GO:0033047)2.79945064
115regulation of sister chromatid segregation (GO:0033045)2.79945064
116negative regulation of DNA-dependent DNA replication (GO:2000104)2.78802961
117monoubiquitinated protein deubiquitination (GO:0035520)2.77564647
118somatic diversification of immune receptors via somatic mutation (GO:0002566)2.77436697
119somatic hypermutation of immunoglobulin genes (GO:0016446)2.77436697
120telomere maintenance (GO:0000723)2.75352667
121chromatin assembly (GO:0031497)2.75271985
122negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.73231343
123mitotic spindle assembly checkpoint (GO:0007094)2.73199268
124telomere organization (GO:0032200)2.72747763
125mitotic G2/M transition checkpoint (GO:0044818)2.71524965
126RNA splicing, via transesterification reactions (GO:0000375)2.70983497
127nuclear envelope organization (GO:0006998)2.70514537

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.98850836
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.39039660
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.77744657
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.55053611
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.87201543
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.59609913
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.58512583
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.58065199
9AR_21909140_ChIP-Seq_LNCAP_Human2.57770478
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.56404090
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.52950896
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.48900190
13E2F1_21310950_ChIP-Seq_MCF-7_Human2.37932397
14* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.30588742
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.25783080
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.19954208
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.17485426
18ELK1_19687146_ChIP-ChIP_HELA_Human2.12097122
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.11066583
20* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.10105463
21* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04691338
22HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.04536194
23VDR_23849224_ChIP-Seq_CD4+_Human2.03924155
24E2F7_22180533_ChIP-Seq_HELA_Human10.2860942
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.98180851
26* XRN2_22483619_ChIP-Seq_HELA_Human1.96237697
27ETS1_20019798_ChIP-Seq_JURKAT_Human1.95623608
28SALL1_21062744_ChIP-ChIP_HESCs_Human1.94852005
29EWS_26573619_Chip-Seq_HEK293_Human1.86945823
30TP63_19390658_ChIP-ChIP_HaCaT_Human1.81228052
31* FOXP3_21729870_ChIP-Seq_TREG_Human1.80666360
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.80204732
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77868019
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76797576
35* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.74364017
36RBPJ_22232070_ChIP-Seq_NCS_Mouse1.65885892
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.64663227
38FUS_26573619_Chip-Seq_HEK293_Human1.63120652
39DCP1A_22483619_ChIP-Seq_HELA_Human1.62347019
40TTF2_22483619_ChIP-Seq_HELA_Human1.61318152
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60819802
42* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.58283731
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.57708646
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.56988491
45* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.53852009
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51522835
47PADI4_21655091_ChIP-ChIP_MCF-7_Human1.46173698
48MYC_22102868_ChIP-Seq_BL_Human1.46152890
49POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39141706
50* GABP_19822575_ChIP-Seq_HepG2_Human1.38025205
51* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37660177
52* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.37590604
53NANOG_18555785_ChIP-Seq_MESCs_Mouse1.37057919
54CIITA_25753668_ChIP-Seq_RAJI_Human1.37015847
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.36834195
56KDM5A_27292631_Chip-Seq_BREAST_Human1.35658863
57SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.35582207
58NANOG_16153702_ChIP-ChIP_HESCs_Human1.32988296
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31650171
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30573747
61* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.27912625
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.26300792
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.23800994
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22199486
65ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21575786
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.19571261
67KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.19042836
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.19042836
69KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.19042836
70SOX2_16153702_ChIP-ChIP_HESCs_Human1.15087114
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13469087
72TFEB_21752829_ChIP-Seq_HELA_Human1.12644662
73ZNF274_21170338_ChIP-Seq_K562_Hela1.11666459
74E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11191453
75TAF15_26573619_Chip-Seq_HEK293_Human1.09861630
76VDR_22108803_ChIP-Seq_LS180_Human1.07234444
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.05955862
78IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.05863735
79SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.03927630
80IGF1R_20145208_ChIP-Seq_DFB_Human1.02987987
81E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02932010
82* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.02756878
83FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.00872220
84MYC_18940864_ChIP-ChIP_HL60_Human0.99636785
85POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97542447
86SPI1_23547873_ChIP-Seq_NB4_Human0.97532215
87* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96639582
88* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.96317595
89KLF4_18555785_ChIP-Seq_MESCs_Mouse0.96197764
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95924240
91NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.95414955
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.93666952
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92719746
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90567768
95FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89809105
96RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89724509
97NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.89541603
98CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88893699
99PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.88754374
100NOTCH1_21737748_ChIP-Seq_TLL_Human0.88422717
101HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88239721
102NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.87680479
103POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.86856164
104HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85465163
105STAT3_1855785_ChIP-Seq_MESCs_Mouse0.85438756
106P300_19829295_ChIP-Seq_ESCs_Human0.83844586
107PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.83397959
108* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83305053
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.82561205
110SOX17_20123909_ChIP-Seq_XEN_Mouse0.82030258
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.81899900
112DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80779732
113TCF3_18692474_ChIP-Seq_MEFs_Mouse0.79365840
114SRF_21415370_ChIP-Seq_HL-1_Mouse0.79326327
115CHD1_26751641_Chip-Seq_LNCaP_Human0.77842219
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.76344421
117MYB_26560356_Chip-Seq_TH1_Human0.75499976
118CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.75221275
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74472530
120MYB_26560356_Chip-Seq_TH2_Human0.74386614
121SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.73644819
122DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.73469901
123YY1_21170310_ChIP-Seq_MESCs_Mouse0.73122075
124IRF1_19129219_ChIP-ChIP_H3396_Human0.72877160
125ESR1_15608294_ChIP-ChIP_MCF-7_Human0.70695093
126ELK1_22589737_ChIP-Seq_MCF10A_Human0.70680476
127EZH2_27294783_Chip-Seq_NPCs_Mouse0.70258584
128WT1_19549856_ChIP-ChIP_CCG9911_Human0.69478422

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.04171513
2MP0003693_abnormal_embryo_hatching4.03563997
3MP0008057_abnormal_DNA_replication3.85776986
4MP0003111_abnormal_nucleus_morphology3.48049057
5MP0004957_abnormal_blastocyst_morpholog3.42517857
6MP0003077_abnormal_cell_cycle3.39134597
7MP0006292_abnormal_olfactory_placode2.78374920
8MP0008007_abnormal_cellular_replicative2.74770694
9MP0008058_abnormal_DNA_repair2.66167727
10MP0010352_gastrointestinal_tract_polyps2.47266227
11MP0010307_abnormal_tumor_latency2.21531668
12MP0008932_abnormal_embryonic_tissue2.19231000
13MP0003123_paternal_imprinting2.11514310
14MP0002396_abnormal_hematopoietic_system2.06693701
15MP0000350_abnormal_cell_proliferation2.02182538
16MP0008877_abnormal_DNA_methylation2.00641765
17MP0001730_embryonic_growth_arrest1.98154660
18MP0005076_abnormal_cell_differentiation1.80472331
19MP0004808_abnormal_hematopoietic_stem1.65419076
20MP0005380_embryogenesis_phenotype1.60682183
21MP0001672_abnormal_embryogenesis/_devel1.60682183
22MP0003890_abnormal_embryonic-extraembry1.57852333
23MP0003121_genomic_imprinting1.56320905
24MP0001697_abnormal_embryo_size1.52687781
25MP0010030_abnormal_orbit_morphology1.51914476
26MP0004197_abnormal_fetal_growth/weight/1.49521072
27MP0000490_abnormal_crypts_of1.49187422
28MP0003984_embryonic_growth_retardation1.48232457
29MP0002088_abnormal_embryonic_growth/wei1.45552907
30MP0002084_abnormal_developmental_patter1.39389249
31MP0002085_abnormal_embryonic_tissue1.37890380
32MP0008789_abnormal_olfactory_epithelium1.36806244
33MP0003567_abnormal_fetal_cardiomyocyte1.36703519
34MP0001293_anophthalmia1.35876257
35MP0008995_early_reproductive_senescence1.34420302
36MP0002086_abnormal_extraembryonic_tissu1.33755556
37MP0003786_premature_aging1.30429813
38MP0009053_abnormal_anal_canal1.30247980
39MP0000537_abnormal_urethra_morphology1.30050764
40MP0002080_prenatal_lethality1.27399907
41MP0001188_hyperpigmentation1.27316311
42MP0002233_abnormal_nose_morphology1.25285056
43MP0003937_abnormal_limbs/digits/tail_de1.22961052
44MP0002009_preneoplasia1.22874367
45MP0002019_abnormal_tumor_incidence1.18189418
46MP0005499_abnormal_olfactory_system1.17628376
47MP0005394_taste/olfaction_phenotype1.17628376
48MP0006072_abnormal_retinal_apoptosis1.17463495
49MP0006035_abnormal_mitochondrial_morpho1.17078394
50MP0003763_abnormal_thymus_physiology1.15983869
51MP0000313_abnormal_cell_death1.15698211
52MP0002166_altered_tumor_susceptibility1.12724176
53MP0003705_abnormal_hypodermis_morpholog1.09974452
54MP0003315_abnormal_perineum_morphology1.09337541
55MP0001529_abnormal_vocalization1.08501618
56MP0002006_tumorigenesis1.07192714
57MP0002102_abnormal_ear_morphology1.06690325
58MP0001545_abnormal_hematopoietic_system1.04666229
59MP0005397_hematopoietic_system_phenotyp1.04666229
60MP0000703_abnormal_thymus_morphology1.02751617
61MP0000569_abnormal_digit_pigmentation1.02123738
62MP0003941_abnormal_skin_development1.01949715
63MP0006054_spinal_hemorrhage1.01584471
64MP0000647_abnormal_sebaceous_gland1.00894935
65MP0002398_abnormal_bone_marrow1.00618030
66MP0009333_abnormal_splenocyte_physiolog0.96450234
67MP0002210_abnormal_sex_determination0.96095013
68MP0009703_decreased_birth_body0.93608590
69MP0003718_maternal_effect0.93418577
70MP0003787_abnormal_imprinting0.93115682
71MP0003221_abnormal_cardiomyocyte_apopto0.92056734
72MP0000358_abnormal_cell_content/0.91146823
73MP0002160_abnormal_reproductive_system0.91136821
74MP0002092_abnormal_eye_morphology0.90459343
75MP0002111_abnormal_tail_morphology0.89520516
76MP0009672_abnormal_birth_weight0.88965091
77MP0000432_abnormal_head_morphology0.88930759
78MP0002722_abnormal_immune_system0.86922668
79MP0001915_intracranial_hemorrhage0.86844894
80MP0002938_white_spotting0.86082906
81MP0001286_abnormal_eye_development0.85663100
82MP0003136_yellow_coat_color0.85338399
83MP0002751_abnormal_autonomic_nervous0.85094632
84MP0005395_other_phenotype0.84936064
85MP0000516_abnormal_urinary_system0.83680774
86MP0005367_renal/urinary_system_phenotyp0.83680774
87MP0001145_abnormal_male_reproductive0.83404313
88MP0004264_abnormal_extraembryonic_tissu0.82783141
89MP0000689_abnormal_spleen_morphology0.82242713
90MP0000858_altered_metastatic_potential0.81644959
91MP0000428_abnormal_craniofacial_morphol0.81201083
92MP0003861_abnormal_nervous_system0.80678088
93MP0005023_abnormal_wound_healing0.80024005
94MP0009278_abnormal_bone_marrow0.79481822
95MP0000733_abnormal_muscle_development0.78747254
96MP0001835_abnormal_antigen_presentation0.78383896
97MP0002234_abnormal_pharynx_morphology0.78335476
98MP0003448_altered_tumor_morphology0.78021184
99MP0001119_abnormal_female_reproductive0.77257277
100MP0000372_irregular_coat_pigmentation0.76785994
101MP0003566_abnormal_cell_adhesion0.75902066
102MP0005391_vision/eye_phenotype0.75336427
103MP0003385_abnormal_body_wall0.75000066
104MP0001929_abnormal_gametogenesis0.74838947
105MP0002429_abnormal_blood_cell0.73343003
106MP0003186_abnormal_redox_activity0.73278065
107MP0000653_abnormal_sex_gland0.72654082
108MP0005408_hypopigmentation0.72310065
109MP0003699_abnormal_female_reproductive0.72193693
110MP0003300_gastrointestinal_ulcer0.71981163
111MP0009697_abnormal_copulation0.71242797
112MP0003943_abnormal_hepatobiliary_system0.71206101
113MP0003698_abnormal_male_reproductive0.71041791
114MP0003935_abnormal_craniofacial_develop0.70689508
115MP0002095_abnormal_skin_pigmentation0.70374432
116MP0000716_abnormal_immune_system0.69970746
117MP0003755_abnormal_palate_morphology0.69959896
118MP0002877_abnormal_melanocyte_morpholog0.68838600
119MP0000049_abnormal_middle_ear0.68717964
120MP0000627_abnormal_mammary_gland0.68467620
121MP0005187_abnormal_penis_morphology0.67696074
122MP0001800_abnormal_humoral_immune0.67250065
123MP0005621_abnormal_cell_physiology0.66864799
124MP0002697_abnormal_eye_size0.65661455
125MP0005389_reproductive_system_phenotype0.65151952
126MP0002452_abnormal_antigen_presenting0.64960251
127MP0001177_atelectasis0.64704210
128MP0002161_abnormal_fertility/fecundity0.64393799
129MP0005384_cellular_phenotype0.63889423
130MP0003119_abnormal_digestive_system0.63820217
131MP0003115_abnormal_respiratory_system0.62207018
132MP0006036_abnormal_mitochondrial_physio0.61084990
133MP0001299_abnormal_eye_distance/0.60095321
134MP0000427_abnormal_hair_cycle0.59170726
135MP0000383_abnormal_hair_follicle0.58835758
136MP0000631_abnormal_neuroendocrine_gland0.57290848

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.10747899
2Birth length less than 3rd percentile (HP:0003561)3.95506775
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.75351901
4Volvulus (HP:0002580)3.61249196
5Abnormality of chromosome stability (HP:0003220)3.28656896
6Colon cancer (HP:0003003)3.26456473
7Reticulocytopenia (HP:0001896)3.00838359
8Meckel diverticulum (HP:0002245)2.90882005
9Abnormality of the preputium (HP:0100587)2.84694219
10Aplasia/Hypoplasia of the uvula (HP:0010293)2.81967989
11Medulloblastoma (HP:0002885)2.81239283
12Ectopic kidney (HP:0000086)2.78315538
13Abnormality of the ileum (HP:0001549)2.76713364
14Patellar aplasia (HP:0006443)2.73163013
15Selective tooth agenesis (HP:0001592)2.71289601
16Abnormality of the anterior horn cell (HP:0006802)2.63706419
17Degeneration of anterior horn cells (HP:0002398)2.63706419
18Cortical dysplasia (HP:0002539)2.63469389
19Breast hypoplasia (HP:0003187)2.61755971
20Deviation of the thumb (HP:0009603)2.58517810
2111 pairs of ribs (HP:0000878)2.58414113
22Aplasia/Hypoplasia of the patella (HP:0006498)2.58173407
23Myelodysplasia (HP:0002863)2.55445235
24Proximal placement of thumb (HP:0009623)2.54865351
25Abnormality of methionine metabolism (HP:0010901)2.50626048
26Impulsivity (HP:0100710)2.42789285
27Short 4th metacarpal (HP:0010044)2.38556575
28Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.38556575
29Small intestinal stenosis (HP:0012848)2.36836459
30Duodenal stenosis (HP:0100867)2.36836459
31Gonadotropin excess (HP:0000837)2.35411144
32Increased nuchal translucency (HP:0010880)2.34130307
33Septo-optic dysplasia (HP:0100842)2.27393115
34Biliary tract neoplasm (HP:0100574)2.24776610
35Absent radius (HP:0003974)2.24667087
36Multiple enchondromatosis (HP:0005701)2.23661123
37Acute myeloid leukemia (HP:0004808)2.22383341
38Atresia of the external auditory canal (HP:0000413)2.21800986
39Abnormality of the fingertips (HP:0001211)2.19066707
40Abnormal lung lobation (HP:0002101)2.18899109
41Neoplasm of the pancreas (HP:0002894)2.18337247
42Aplastic anemia (HP:0001915)2.18067137
43Increased hepatocellular lipid droplets (HP:0006565)2.14941594
44Nephroblastoma (Wilms tumor) (HP:0002667)2.14221639
45Bifid tongue (HP:0010297)2.13739587
46Sloping forehead (HP:0000340)2.12372586
47Absent thumb (HP:0009777)2.12332908
48Oral leukoplakia (HP:0002745)2.09372931
49Rhabdomyosarcoma (HP:0002859)2.08864413
50Long eyelashes (HP:0000527)2.08574804
51Papillary thyroid carcinoma (HP:0002895)2.08490333
52Abnormality of the labia minora (HP:0012880)2.07806959
53Absent forearm bone (HP:0003953)2.06929624
54Aplasia involving forearm bones (HP:0009822)2.06929624
55Pancreatic islet-cell hyperplasia (HP:0004510)2.05586387
56Intestinal atresia (HP:0011100)2.04189437
57Missing ribs (HP:0000921)2.02400171
58Embryonal renal neoplasm (HP:0011794)2.02198136
59Oligodactyly (hands) (HP:0001180)2.01866565
60Microvesicular hepatic steatosis (HP:0001414)2.01300137
61Short thumb (HP:0009778)2.00385026
62Abnormality of the duodenum (HP:0002246)1.99673407
63Agnosia (HP:0010524)1.99442753
64Abnormality of aspartate family amino acid metabolism (HP:0010899)1.97401700
65Glioma (HP:0009733)1.97193612
66Ependymoma (HP:0002888)1.96988046
67Abnormality of the septum pellucidum (HP:0007375)1.94658152
68Deep philtrum (HP:0002002)1.93912270
69Macrocytic anemia (HP:0001972)1.93843588
70Abnormality of the carotid arteries (HP:0005344)1.92024890
71Blepharitis (HP:0000498)1.90255777
72Megaloblastic anemia (HP:0001889)1.90076735
73Aplasia/Hypoplasia of the sternum (HP:0006714)1.89620838
74Bone marrow hypocellularity (HP:0005528)1.88796490
75Methylmalonic acidemia (HP:0002912)1.88400733
76Choanal atresia (HP:0000453)1.87857030
77Homocystinuria (HP:0002156)1.87581236
78Abnormality of homocysteine metabolism (HP:0010919)1.87581236
79Neoplasm of the colon (HP:0100273)1.87500456
80Premature graying of hair (HP:0002216)1.85022386
81Clubbing of toes (HP:0100760)1.84211751
82Cutaneous melanoma (HP:0012056)1.84111425
83Lipid accumulation in hepatocytes (HP:0006561)1.83893668
84Carpal bone hypoplasia (HP:0001498)1.83301981
85Triphalangeal thumb (HP:0001199)1.82944296
86Tracheoesophageal fistula (HP:0002575)1.82242006
87Short middle phalanx of the 5th finger (HP:0004220)1.81230596
88High pitched voice (HP:0001620)1.80171384
89Thrombocytosis (HP:0001894)1.79112666
90Facial hemangioma (HP:0000329)1.78925204
91Malignant gastrointestinal tract tumors (HP:0006749)1.78836785
92Gastrointestinal carcinoma (HP:0002672)1.78836785
93Abnormality of serum amino acid levels (HP:0003112)1.77719971
94Embryonal neoplasm (HP:0002898)1.76984186
95Prominent nose (HP:0000448)1.76488814
96Lymphoma (HP:0002665)1.76016713
97Absent septum pellucidum (HP:0001331)1.75957465
98Supernumerary spleens (HP:0009799)1.75945935
99Stenosis of the external auditory canal (HP:0000402)1.75322721
100Cafe-au-lait spot (HP:0000957)1.73779229
101Rough bone trabeculation (HP:0100670)1.73205694
102Increased serum pyruvate (HP:0003542)1.72244235
103Spinal cord lesions (HP:0100561)1.71899126
104Syringomyelia (HP:0003396)1.71899126
105Premature ovarian failure (HP:0008209)1.71871803
106Gastrointestinal atresia (HP:0002589)1.71652898
107Median cleft lip (HP:0000161)1.71579982
108Abnormal number of incisors (HP:0011064)1.71325470
109Abnormal biliary tract morphology (HP:0012440)1.71157514
110Abnormality of the calcaneus (HP:0008364)1.70040803
111Neoplasm of the small intestine (HP:0100833)1.69338645
112Acute encephalopathy (HP:0006846)1.68822143
113Facial cleft (HP:0002006)1.68247658
114Abnormal hair whorl (HP:0010721)1.67871143
115Overlapping toe (HP:0001845)1.67522950
116Basal cell carcinoma (HP:0002671)1.67438361
117Squamous cell carcinoma (HP:0002860)1.65940943
118Hyperglycinemia (HP:0002154)1.65663439
119Acute necrotizing encephalopathy (HP:0006965)1.65238905
120Capillary hemangiomas (HP:0005306)1.64404283
121Abnormality of the astrocytes (HP:0100707)1.64193417
122Astrocytoma (HP:0009592)1.64193417
123Esophageal atresia (HP:0002032)1.63178182
124Ovarian neoplasm (HP:0100615)1.62978289
125Arteriovenous malformation (HP:0100026)1.62565365
126Hypoplastic pelvis (HP:0008839)1.62513674
127Thyroid carcinoma (HP:0002890)1.62489841
128Amaurosis fugax (HP:0100576)1.61814258
129Supernumerary bones of the axial skeleton (HP:0009144)1.61690979
130Rib fusion (HP:0000902)1.60993107
131Glossoptosis (HP:0000162)1.60710763
132Abnormality of cells of the erythroid lineage (HP:0012130)1.59404445
133Sandal gap (HP:0001852)1.59184651
134Pallor (HP:0000980)1.58818282
135Pelvic girdle muscle weakness (HP:0003749)1.58262415
136Horseshoe kidney (HP:0000085)1.57850166
137Progressive external ophthalmoplegia (HP:0000590)1.57131773
138Cellular immunodeficiency (HP:0005374)1.57127154
139Aplasia/Hypoplasia of the sacrum (HP:0008517)1.57115493
140Small hand (HP:0200055)1.56372269
141Abdominal situs inversus (HP:0003363)1.56329216
142Abnormality of abdominal situs (HP:0011620)1.56329216
143Supernumerary ribs (HP:0005815)1.56305986
144Optic nerve coloboma (HP:0000588)1.56187010
145Cleft eyelid (HP:0000625)1.56086182
146Cutis marmorata (HP:0000965)1.56030487
147Abnormality of the pons (HP:0007361)1.55761095
148Clitoromegaly (HP:0000057)1.55358646
149Hypoplasia of the radius (HP:0002984)1.55191782
150Postnatal microcephaly (HP:0005484)1.54872668
151Preaxial hand polydactyly (HP:0001177)1.53900227

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.52479776
2WEE13.22174285
3SRPK12.99920341
4NEK22.85215946
5EIF2AK12.61268051
6BUB12.60365740
7MKNK12.49839212
8TRIM282.44139592
9BRSK22.37899453
10PLK42.28993688
11CDK122.27422512
12ACVR1B2.12043994
13TTK2.02467497
14TNIK1.91285060
15MKNK21.90984917
16PLK31.88187025
17PASK1.84745631
18AURKB1.80155106
19EIF2AK31.77143083
20PLK11.76694168
21ATR1.75172970
22TLK11.72303966
23RPS6KA41.70861593
24STK101.68584451
25TSSK61.60872952
26NEK11.59704791
27NUAK11.59692653
28VRK11.51595057
29CDK71.49084261
30BMPR1B1.47852391
31VRK21.47360699
32ZAK1.46978914
33RPS6KB21.45220524
34NME21.45211248
35PBK1.44721989
36CHEK21.41235220
37WNK31.38696778
38BCR1.38222384
39STK41.35953204
40BRD41.35665870
41CHEK11.35182269
42TAF11.31919617
43MAP3K81.31566878
44DYRK31.30059636
45CDK61.28815946
46NME11.28380874
47STK31.26466560
48TESK21.22762395
49STK161.21568913
50CDK41.21233624
51ATM1.15025289
52NEK91.14262411
53LATS11.10270051
54PIM11.06762970
55EIF2AK21.06568772
56TGFBR11.05218415
57BRSK10.98304503
58MELK0.97876913
59EEF2K0.97813647
60SCYL20.87937888
61MST40.87757232
62EPHA20.86929620
63CDK20.86799258
64FRK0.82901359
65ERBB40.82801314
66MAP3K40.81509062
67AURKA0.75288432
68MAP4K10.74857079
69TEC0.74233536
70STK240.73846435
71CDK10.73324895
72FLT30.72001898
73JAK30.69942087
74CHUK0.68905605
75RPS6KA50.67519673
76MAP3K100.65404750
77PAK40.64780668
78LRRK20.63163382
79ERBB30.63118848
80CSNK2A20.63076418
81PLK20.62760809
82PDK20.62690524
83CLK10.62322660
84YES10.60312375
85NLK0.59640021
86ALK0.58127746
87CDK30.57207979
88CSNK2A10.56129487
89CSNK1G10.54556927
90IRAK40.54553318
91TRPM70.54145039
92CDK90.53991270
93TESK10.52861671
94BTK0.52279096
95CCNB10.51818676
96STK38L0.50055337
97STK390.49782878
98MTOR0.48750688
99TXK0.47220578
100FGFR10.44396794
101PRKDC0.43863530
102KSR10.42564852
103ITK0.41989243
104PNCK0.38413767
105MAPK140.37634234
106PAK20.36288563
107CDK80.35453071
108PKN20.35237361
109DYRK20.35106136
110CSNK1D0.34877013
111MAP3K140.34082242
112NEK60.33540294
113PIM20.32930243
114MAP2K70.32214779
115MARK30.31988944
116CSNK1E0.31918667
117AKT10.31863795
118OXSR10.30576836
119CSF1R0.30418596
120FGFR30.29617023
121IKBKB0.29218641
122PAK10.28206488
123PTK60.27998645
124CSNK1A1L0.27785943
125INSRR0.27507745
126PRKACB0.23654973
127SIK30.23629097
128CSNK1G20.23322153
129BRAF0.22770716
130CSNK1G30.20953446
131CAMK1G0.20584209
132AKT30.20384706

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.20857676
2Mismatch repair_Homo sapiens_hsa034303.95895832
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.37067438
4* Spliceosome_Homo sapiens_hsa030403.08124769
5RNA transport_Homo sapiens_hsa030133.03206817
6Cell cycle_Homo sapiens_hsa041102.95576445
7Homologous recombination_Homo sapiens_hsa034402.81115787
8One carbon pool by folate_Homo sapiens_hsa006702.74953714
9Base excision repair_Homo sapiens_hsa034102.58635505
10Nucleotide excision repair_Homo sapiens_hsa034202.54538577
11Non-homologous end-joining_Homo sapiens_hsa034502.51394562
12Ribosome_Homo sapiens_hsa030102.42935033
13Fanconi anemia pathway_Homo sapiens_hsa034602.40858738
14RNA polymerase_Homo sapiens_hsa030202.34420043
15Proteasome_Homo sapiens_hsa030502.11172641
16RNA degradation_Homo sapiens_hsa030181.95137164
17mRNA surveillance pathway_Homo sapiens_hsa030151.92008845
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.91913678
19Basal transcription factors_Homo sapiens_hsa030221.91578163
20p53 signaling pathway_Homo sapiens_hsa041151.86293526
21Pyrimidine metabolism_Homo sapiens_hsa002401.83208905
22Systemic lupus erythematosus_Homo sapiens_hsa053221.79205194
23Propanoate metabolism_Homo sapiens_hsa006401.54709291
24Steroid biosynthesis_Homo sapiens_hsa001001.42586689
25Antigen processing and presentation_Homo sapiens_hsa046121.33615997
26Viral carcinogenesis_Homo sapiens_hsa052031.29935360
27Pyruvate metabolism_Homo sapiens_hsa006201.29553203
28Herpes simplex infection_Homo sapiens_hsa051681.29098789
29Epstein-Barr virus infection_Homo sapiens_hsa051691.27311464
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.15057398
31MicroRNAs in cancer_Homo sapiens_hsa052061.14769577
32Parkinsons disease_Homo sapiens_hsa050121.10413986
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.06814265
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.06489329
35Huntingtons disease_Homo sapiens_hsa050161.06310459
36Small cell lung cancer_Homo sapiens_hsa052221.05234539
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04999096
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.04768692
39NF-kappa B signaling pathway_Homo sapiens_hsa040641.03645506
40Oxidative phosphorylation_Homo sapiens_hsa001901.03607411
41HTLV-I infection_Homo sapiens_hsa051660.94972075
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94858620
43Legionellosis_Homo sapiens_hsa051340.94771462
44Transcriptional misregulation in cancer_Homo sapiens_hsa052020.93987972
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.92017236
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90790431
47Purine metabolism_Homo sapiens_hsa002300.89230267
48Primary immunodeficiency_Homo sapiens_hsa053400.88029866
49Measles_Homo sapiens_hsa051620.87474529
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87317651
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83969547
52Selenocompound metabolism_Homo sapiens_hsa004500.83593859
53Protein export_Homo sapiens_hsa030600.83574938
54TGF-beta signaling pathway_Homo sapiens_hsa043500.80715400
55Biosynthesis of amino acids_Homo sapiens_hsa012300.80635566
56NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79170237
57Viral myocarditis_Homo sapiens_hsa054160.76768111
58Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76294248
59Thyroid cancer_Homo sapiens_hsa052160.74413218
60Adherens junction_Homo sapiens_hsa045200.72989341
61Oocyte meiosis_Homo sapiens_hsa041140.72366669
62Carbon metabolism_Homo sapiens_hsa012000.69159210
63Hepatitis B_Homo sapiens_hsa051610.68658786
64Hematopoietic cell lineage_Homo sapiens_hsa046400.67223604
65Chronic myeloid leukemia_Homo sapiens_hsa052200.66777046
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.66769472
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65646155
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65606829
69Fatty acid elongation_Homo sapiens_hsa000620.64690759
70Apoptosis_Homo sapiens_hsa042100.64274162
71Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60216272
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60004151
73Allograft rejection_Homo sapiens_hsa053300.59071212
74Prostate cancer_Homo sapiens_hsa052150.58760702
75Vitamin digestion and absorption_Homo sapiens_hsa049770.56690564
76Colorectal cancer_Homo sapiens_hsa052100.56669985
77Alcoholism_Homo sapiens_hsa050340.56487778
78Hippo signaling pathway_Homo sapiens_hsa043900.55001347
79Influenza A_Homo sapiens_hsa051640.54887422
80Basal cell carcinoma_Homo sapiens_hsa052170.53058168
81Graft-versus-host disease_Homo sapiens_hsa053320.52459876
82Leishmaniasis_Homo sapiens_hsa051400.52229616
83Notch signaling pathway_Homo sapiens_hsa043300.51724763
84Autoimmune thyroid disease_Homo sapiens_hsa053200.51183389
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50789022
86Shigellosis_Homo sapiens_hsa051310.49609505
87Pancreatic cancer_Homo sapiens_hsa052120.47896161
88Glutathione metabolism_Homo sapiens_hsa004800.47618401
89Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45338359
90Pathways in cancer_Homo sapiens_hsa052000.45179361
91Lysine degradation_Homo sapiens_hsa003100.44852714
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44430969
93Leukocyte transendothelial migration_Homo sapiens_hsa046700.43981957
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43016457
95Alzheimers disease_Homo sapiens_hsa050100.42378273
96Asthma_Homo sapiens_hsa053100.42203104
97Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41546136
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.41032562
99Hedgehog signaling pathway_Homo sapiens_hsa043400.40991033
100Fatty acid metabolism_Homo sapiens_hsa012120.40721483
101Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39688815
102Metabolic pathways_Homo sapiens_hsa011000.39477013
103Toxoplasmosis_Homo sapiens_hsa051450.38477185
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.37677222
105Proteoglycans in cancer_Homo sapiens_hsa052050.36451827
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.35378026
107T cell receptor signaling pathway_Homo sapiens_hsa046600.34159409
108Bladder cancer_Homo sapiens_hsa052190.33589481
109N-Glycan biosynthesis_Homo sapiens_hsa005100.32722069
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.32579280
111TNF signaling pathway_Homo sapiens_hsa046680.31965646
112Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29936628
113PI3K-Akt signaling pathway_Homo sapiens_hsa041510.29796728
114Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.29110378
115ECM-receptor interaction_Homo sapiens_hsa045120.29062858
116Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28945615
117Folate biosynthesis_Homo sapiens_hsa007900.28795878
118FoxO signaling pathway_Homo sapiens_hsa040680.28465614
119Cysteine and methionine metabolism_Homo sapiens_hsa002700.27550419
120HIF-1 signaling pathway_Homo sapiens_hsa040660.26942684
121Acute myeloid leukemia_Homo sapiens_hsa052210.26153678
122Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26044982
123B cell receptor signaling pathway_Homo sapiens_hsa046620.25863849
124Vitamin B6 metabolism_Homo sapiens_hsa007500.25690138
125Pentose phosphate pathway_Homo sapiens_hsa000300.25603916
126Melanoma_Homo sapiens_hsa052180.25521921
127Type I diabetes mellitus_Homo sapiens_hsa049400.24183117
128Non-small cell lung cancer_Homo sapiens_hsa052230.23842676
129Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.22565162
130Wnt signaling pathway_Homo sapiens_hsa043100.22336585
131Circadian rhythm_Homo sapiens_hsa047100.18312761
132Butanoate metabolism_Homo sapiens_hsa006500.18266427
133Fatty acid degradation_Homo sapiens_hsa000710.15483696
134Peroxisome_Homo sapiens_hsa041460.14711894
135Caffeine metabolism_Homo sapiens_hsa002320.14497169
136Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.12465642
137Tight junction_Homo sapiens_hsa045300.11809870
138Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.11192982
139Phototransduction_Homo sapiens_hsa047440.10693412
140Retinol metabolism_Homo sapiens_hsa008300.08433393
141Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.06870748
142Regulation of autophagy_Homo sapiens_hsa041400.02811887

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