PRR15L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1angiotensin maturation (GO:0002003)8.29223310
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)6.90592482
3cytidine deamination (GO:0009972)6.77703902
4cytidine metabolic process (GO:0046087)6.77703902
5cytidine catabolic process (GO:0006216)6.77703902
6regulation of guanylate cyclase activity (GO:0031282)6.62780172
7NADH metabolic process (GO:0006734)6.15785972
8intestinal epithelial cell development (GO:0060576)6.01955876
9negative regulation of keratinocyte proliferation (GO:0010839)5.72847466
10pyrimidine ribonucleoside catabolic process (GO:0046133)5.67725438
11sulfate transmembrane transport (GO:1902358)5.51446067
12epoxygenase P450 pathway (GO:0019373)5.50593767
13aminoglycoside antibiotic metabolic process (GO:0030647)5.41762924
14calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)5.23541565
15intestinal absorption (GO:0050892)5.19580455
16sulfate transport (GO:0008272)5.07116996
17lipoprotein transport (GO:0042953)4.97316727
18surfactant homeostasis (GO:0043129)4.88365555
19positive regulation of guanylate cyclase activity (GO:0031284)4.85052614
20endocrine process (GO:0050886)4.76836857
21regulation of systemic arterial blood pressure by hormone (GO:0001990)4.76836857
22regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.76836857
233-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.76644143
24purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.76644143
25fat-soluble vitamin biosynthetic process (GO:0042362)4.75879062
26regulation of bile acid biosynthetic process (GO:0070857)4.73544753
27positive regulation of digestive system process (GO:0060456)4.70059966
28fructose metabolic process (GO:0006000)4.65883546
29intestinal cholesterol absorption (GO:0030299)4.65624711
30regulation of autophagic vacuole assembly (GO:2000785)4.63007357
31negative regulation of epidermal cell differentiation (GO:0045605)4.62638023
32regulation of cellular extravasation (GO:0002691)4.60347219
33sulfur compound transport (GO:0072348)4.46643588
34cellular glucuronidation (GO:0052695)4.43853600
35daunorubicin metabolic process (GO:0044597)4.39854715
36polyketide metabolic process (GO:0030638)4.39854715
37doxorubicin metabolic process (GO:0044598)4.39854715
38digestion (GO:0007586)4.39207793
39regulation of vitamin metabolic process (GO:0030656)4.38892389
40uronic acid metabolic process (GO:0006063)4.36491290
41glucuronate metabolic process (GO:0019585)4.36491290
42transepithelial transport (GO:0070633)4.33683740
43UDP-N-acetylglucosamine metabolic process (GO:0006047)4.33571575
44drug transmembrane transport (GO:0006855)4.29583070
45regulation of systemic arterial blood pressure (GO:0003073)4.28148294
46sulfur amino acid catabolic process (GO:0000098)4.27835683
47renal system process involved in regulation of blood volume (GO:0001977)4.24690786
48receptor guanylyl cyclase signaling pathway (GO:0007168)4.21169067
49bundle of His cell to Purkinje myocyte communication (GO:0086069)4.15389528
50urea cycle (GO:0000050)4.14961718
51regulation of apoptotic process involved in morphogenesis (GO:1902337)4.11557067
52negative regulation of epidermis development (GO:0045683)4.10806526
53regulation of vacuole organization (GO:0044088)4.09543101
54chemical homeostasis within a tissue (GO:0048875)4.07969355
55positive regulation of respiratory burst (GO:0060267)4.06326128
56regulation of cGMP biosynthetic process (GO:0030826)4.04624404
57positive regulation of pseudopodium assembly (GO:0031274)4.03470516
58diol metabolic process (GO:0034311)3.93482549
59positive regulation of epidermal cell differentiation (GO:0045606)3.91297236
60urea metabolic process (GO:0019627)3.90862945
61negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)3.87814566
62flavonoid metabolic process (GO:0009812)3.86660270
63regulation of keratinocyte proliferation (GO:0010837)3.83572141
64very-low-density lipoprotein particle assembly (GO:0034379)3.79773236
65cardiovascular system development (GO:0072358)3.78015786
66diacylglycerol metabolic process (GO:0046339)3.74836044
67keratinocyte development (GO:0003334)3.73884829
68hormone catabolic process (GO:0042447)3.71009503
69transcytosis (GO:0045056)3.69196611
70regulation of chemokine secretion (GO:0090196)3.69017750
71adhesion of symbiont to host cell (GO:0044650)3.63921770
72virion attachment to host cell (GO:0019062)3.63921770
73phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.63905252
74thyroid hormone metabolic process (GO:0042403)3.62741972
75drug transport (GO:0015893)3.62542626
76fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.62343044
77GDP-mannose metabolic process (GO:0019673)3.59448108
78regulation of pseudopodium assembly (GO:0031272)3.58437069
79nitrogen cycle metabolic process (GO:0071941)3.57566211
80membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.57512057
81renal absorption (GO:0070293)3.54715703
82regulation of cholesterol homeostasis (GO:2000188)3.52560838
83ethanol oxidation (GO:0006069)3.52094577
84glycolipid catabolic process (GO:0019377)3.49861645
85glomerular filtration (GO:0003094)3.49683779
86bile acid and bile salt transport (GO:0015721)3.48401377
87peptide hormone processing (GO:0016486)3.44282486
88glycosphingolipid catabolic process (GO:0046479)3.42849415
89oligosaccharide biosynthetic process (GO:0009312)3.42553725
90peptide catabolic process (GO:0043171)3.40106196
91auditory receptor cell differentiation (GO:0042491)3.40050181
92membrane repolarization during action potential (GO:0086011)3.38594746
93O-glycan processing (GO:0016266)3.38269027
94thyroid hormone generation (GO:0006590)3.37767076
95negative regulation of protein tyrosine kinase activity (GO:0061099)3.36553941
96nucleoside diphosphate biosynthetic process (GO:0009133)3.36168156
97positive regulation of Cdc42 GTPase activity (GO:0043089)3.35841865
98drug catabolic process (GO:0042737)3.35562859
99positive regulation of glycoprotein biosynthetic process (GO:0010560)3.33623033
100sphingomyelin metabolic process (GO:0006684)3.32015689
101positive regulation of glycoprotein metabolic process (GO:1903020)3.31222977
102glutamine family amino acid biosynthetic process (GO:0009084)3.27870875
103epithelial structure maintenance (GO:0010669)3.26525408
104regulation of cGMP metabolic process (GO:0030823)3.26460620
105homocysteine metabolic process (GO:0050667)3.24642085
106regulation of viral release from host cell (GO:1902186)3.23590762
107plasma lipoprotein particle assembly (GO:0034377)3.22846600
108pyrimidine-containing compound transmembrane transport (GO:0072531)3.22225853
109sphingoid metabolic process (GO:0046519)3.21701913
110renal filtration (GO:0097205)3.21028388
111multicellular organismal water homeostasis (GO:0050891)3.20979725
112regulation of water loss via skin (GO:0033561)3.19983941
113excretion (GO:0007588)3.19056724
114ethanol metabolic process (GO:0006067)3.19030953
115regulation of triglyceride catabolic process (GO:0010896)3.18932868
116regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.16653740
117bicarbonate transport (GO:0015701)3.15286472
118maintenance of gastrointestinal epithelium (GO:0030277)3.15276677
119antibacterial humoral response (GO:0019731)3.14144032
120organic cation transport (GO:0015695)3.13290360
121digestive system process (GO:0022600)3.12355454
122glandular epithelial cell differentiation (GO:0002067)3.11353720
123adhesion of symbiont to host (GO:0044406)3.11150438
124vitamin transport (GO:0051180)3.11115584
125negative regulation of T cell differentiation in thymus (GO:0033085)3.10792797
126antimicrobial humoral response (GO:0019730)3.06770160
127actin filament depolymerization (GO:0030042)3.06324087
128renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.04541393
129positive regulation of lipid catabolic process (GO:0050996)3.04153837
130nucleotide-sugar biosynthetic process (GO:0009226)3.03880373
131regulation of respiratory burst (GO:0060263)3.02056390
132sodium ion homeostasis (GO:0055078)3.01614181
133positive regulation of fatty acid beta-oxidation (GO:0032000)3.00665284
134regulation of epidermal cell differentiation (GO:0045604)2.99334906
135cellular modified amino acid catabolic process (GO:0042219)2.98300579
136regulation of hydrogen peroxide metabolic process (GO:0010310)2.96375972
137cellular response to nitric oxide (GO:0071732)2.96170500
138branching involved in labyrinthine layer morphogenesis (GO:0060670)2.96111456
139establishment of skin barrier (GO:0061436)2.95049145
140protein-lipid complex assembly (GO:0065005)2.94985195
141exogenous drug catabolic process (GO:0042738)2.94610918
142positive regulation of epidermis development (GO:0045684)2.94360192
143arginine metabolic process (GO:0006525)2.93255608
144glycosylceramide metabolic process (GO:0006677)2.92704525
145vitamin transmembrane transport (GO:0035461)2.92557021
146protein retention in ER lumen (GO:0006621)2.90681828
147endocrine pancreas development (GO:0031018)2.90660423
148phosphate ion transport (GO:0006817)2.89096772
149signal transduction involved in regulation of gene expression (GO:0023019)2.88542224
150primary alcohol catabolic process (GO:0034310)2.88318109
151cGMP-mediated signaling (GO:0019934)2.87998479
152lipoprotein metabolic process (GO:0042157)2.87277803
153desmosome organization (GO:0002934)2.87016674
154somite rostral/caudal axis specification (GO:0032525)2.86637537
155bile acid metabolic process (GO:0008206)2.86407421
156alkaloid metabolic process (GO:0009820)2.85098014
157receptor recycling (GO:0001881)2.84928540
158fucose metabolic process (GO:0006004)2.84684343
159cGMP biosynthetic process (GO:0006182)2.84014144
160arachidonic acid secretion (GO:0050482)2.83813590
161icosanoid secretion (GO:0032309)2.83813590
162icosanoid transport (GO:0071715)2.82640511
163fatty acid derivative transport (GO:1901571)2.82640511
164positive regulation of cGMP biosynthetic process (GO:0030828)2.81671132
165maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.81591070
166phosphate ion transmembrane transport (GO:0035435)2.79647136
167vitamin A metabolic process (GO:0006776)2.79485712
168modified amino acid transport (GO:0072337)2.79191764
169drug metabolic process (GO:0017144)2.78674203
170glycoside metabolic process (GO:0016137)2.77639090
171cellular response to vitamin D (GO:0071305)2.76515685

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.35508697
2CDX2_20551321_ChIP-Seq_CACO-2_Human4.94442496
3SOX2_27498859_Chip-Seq_STOMACH_Mouse3.80062046
4KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.41317117
5KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.41317117
6KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.41317117
7GATA4_25053715_ChIP-Seq_YYC3_Human3.13885172
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.08972463
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.00326288
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.88793053
11SOX2_20726797_ChIP-Seq_SW620_Human2.81534636
12STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.77273673
13GATA6_25053715_ChIP-Seq_YYC3_Human2.71400699
14ESR1_21235772_ChIP-Seq_MCF-7_Human2.64249250
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.43302639
16ESR2_21235772_ChIP-Seq_MCF-7_Human2.18564982
17PPARA_22158963_ChIP-Seq_LIVER_Mouse2.08990593
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.07045003
19VDR_22108803_ChIP-Seq_LS180_Human1.99482382
20CDX2_19796622_ChIP-Seq_MESCs_Mouse1.97469836
21TRIM28_21343339_ChIP-Seq_HEK293_Human1.95871357
22FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.93162268
23NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.90982705
24CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.89884686
25FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.83887103
26FOXO3_23340844_ChIP-Seq_DLD1_Human1.83655405
27SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.83566045
28BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.80458330
29LXR_22292898_ChIP-Seq_THP-1_Human1.79321441
30IRF8_22096565_ChIP-ChIP_GC-B_Human1.76197171
31CLOCK_20551151_ChIP-Seq_293T_Human1.75335336
32ZNF263_19887448_ChIP-Seq_K562_Human1.71171932
33KLF5_25053715_ChIP-Seq_YYC3_Human1.69588293
34RXR_22158963_ChIP-Seq_LIVER_Mouse1.65453560
35THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.64652835
36ESR1_20079471_ChIP-ChIP_T-47D_Human1.64543487
37LXR_22158963_ChIP-Seq_LIVER_Mouse1.62668732
38RACK7_27058665_Chip-Seq_MCF-7_Human1.60812590
39RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57247896
40RUNX1_27514584_Chip-Seq_MCF-7_Human1.55358232
41PPAR_26484153_Chip-Seq_NCI-H1993_Human1.52908367
42TCF3_18692474_ChIP-Seq_MEFs_Mouse1.49614066
43PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.45818000
44* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.43521950
45ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.43108565
46ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.39849300
47KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.38021272
48MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.37195244
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.36989899
50* GATA3_24758297_ChIP-Seq_MCF-7_Human1.36013640
51NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.34484997
52ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.33750257
53SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.33301147
54BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.31967574
55P63_26484246_Chip-Seq_KERATINOCYTES_Human1.29936899
56NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.29640746
57TCF4_18268006_ChIP-ChIP_LS174T_Human1.28188879
58TCF3_18692474_ChIP-Seq_MESCs_Mouse1.26876560
59ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.26636952
60NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.25386929
61KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24011061
62GATA1_22025678_ChIP-Seq_K562_Human1.23017096
63SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19182975
64* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.18876711
65SRY_22984422_ChIP-ChIP_TESTIS_Rat1.18874662
66NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.17821763
67FOXA2_19822575_ChIP-Seq_HepG2_Human1.17410825
68GATA2_21666600_ChIP-Seq_HMVEC_Human1.15743178
69* FOXA1_25552417_ChIP-Seq_VCAP_Human1.15035510
70TET1_21451524_ChIP-Seq_MESCs_Mouse1.14949983
71AR_21909140_ChIP-Seq_LNCAP_Human1.14351788
72CREB1_26743006_Chip-Seq_LNCaP_Human1.12675498
73KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10912752
74SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.10831404
75AHR_22903824_ChIP-Seq_MCF-7_Human1.09810682
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09092936
77NANOG_18692474_ChIP-Seq_MEFs_Mouse1.08809019
78ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07246934
79RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06106890
80JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.04711431
81* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.04155894
82PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.04024763
83FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.03628994
84RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.03463954
85HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02539525
86ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02183469
87SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01203519
88BCOR_27268052_Chip-Seq_Bcells_Human1.00492652
89IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99728460
90GATA2_19941826_ChIP-Seq_K562_Human0.99698865
91TP63_22573176_ChIP-Seq_HFKS_Human0.98991135
92CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98918822
93* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98481891
94HNF4A_19822575_ChIP-Seq_HepG2_Human0.97019251
95ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96756792
96SA1_27219007_Chip-Seq_Bcells_Human0.95385052
97PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.94642707
98CDX2_22108803_ChIP-Seq_LS180_Human0.94146098
99NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.93545140
100CSB_26484114_Chip-Seq_FIBROBLAST_Human0.93459800
101NANOG_18692474_ChIP-Seq_MESCs_Mouse0.92485691
102DROSHA_22980978_ChIP-Seq_HELA_Human0.92399632
103GATA1_19941826_ChIP-Seq_K562_Human0.91579426
104OCT4_18692474_ChIP-Seq_MEFs_Mouse0.90914473
105PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.90361299
106CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.90148912
107BCL6_27268052_Chip-Seq_Bcells_Human0.89671242
108CTCF_27219007_Chip-Seq_Bcells_Human0.89448082
109TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89190147
110SALL4_18804426_ChIP-ChIP_XEN_Mouse0.87593633
111STAT3_1855785_ChIP-Seq_MESCs_Mouse0.87559360
112NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.87357738
113NANOG_20526341_ChIP-Seq_ESCs_Human0.87283732
114FOXM1_26456572_ChIP-Seq_MCF-7_Human0.87220796
115IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.87140617
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.87074387
117CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.86477308
118STAT1_20625510_ChIP-Seq_HELA_Human0.86389362
119IRF1_19129219_ChIP-ChIP_H3396_Human0.85977911
120ERG_21242973_ChIP-ChIP_JURKAT_Human0.85561784
121SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.85018037
122SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.85018037
123RAD21_21589869_ChIP-Seq_MESCs_Mouse0.85010834
124SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.84903952
125GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84705434
126ESET_19884257_ChIP-Seq_ESCs_Mouse0.84255852
127EGR1_23403033_ChIP-Seq_LIVER_Mouse0.83893920
128* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83723124
129TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.83439031
130CEBPB_22108803_ChIP-Seq_LS180_Human0.82945990
131PCGF2_27294783_Chip-Seq_NPCs_Mouse0.82429710
132DNAJC2_21179169_ChIP-ChIP_NT2_Human0.81671690
133PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81284419
134ATF3_27146783_Chip-Seq_COLON_Human0.80637118
135CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.80614330
136SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.79731565
137GATA1_22383799_ChIP-Seq_G1ME_Mouse0.79255346
138* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78824128
139EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.77965736

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle5.62255467
2MP0003283_abnormal_digestive_organ4.18834218
3MP0001666_abnormal_nutrient_absorption4.11499791
4MP0004043_abnormal_pH_regulation3.98360402
5MP0004264_abnormal_extraembryonic_tissu3.96943548
6MP0008004_abnormal_stomach_pH3.79874475
7MP0005360_urolithiasis3.31266163
8MP0000462_abnormal_digestive_system2.93761871
9MP0009840_abnormal_foam_cell2.89713452
10MP0002138_abnormal_hepatobiliary_system2.81516586
11MP0004147_increased_porphyrin_level2.75383698
12MP0004782_abnormal_surfactant_physiolog2.59867712
13MP0005085_abnormal_gallbladder_physiolo2.53551253
14MP0002277_abnormal_respiratory_mucosa2.44079280
15MP0004019_abnormal_vitamin_homeostasis2.40135927
16MP0003315_abnormal_perineum_morphology2.29798219
17MP0001664_abnormal_digestion2.22492475
18MP0009643_abnormal_urine_homeostasis2.19088638
19MP0001765_abnormal_ion_homeostasis2.17750869
20MP0005083_abnormal_biliary_tract2.13810196
21MP0008875_abnormal_xenobiotic_pharmacok2.11894078
22MP0005409_darkened_coat_color2.08858978
23MP0000678_abnormal_parathyroid_gland2.08705407
24MP0000490_abnormal_crypts_of2.04295421
25MP0001873_stomach_inflammation2.03669322
26MP0002139_abnormal_hepatobiliary_system2.03149231
27MP0005365_abnormal_bile_salt2.03061408
28MP0003300_gastrointestinal_ulcer1.98075985
29MP0003252_abnormal_bile_duct1.92938237
30MP0002098_abnormal_vibrissa_morphology1.84905367
31MP0003878_abnormal_ear_physiology1.83757224
32MP0005377_hearing/vestibular/ear_phenot1.83757224
33MP0003866_abnormal_defecation1.83698597
34MP0005381_digestive/alimentary_phenotyp1.82909308
35MP0010155_abnormal_intestine_physiology1.76425646
36MP0002132_abnormal_respiratory_system1.75524785
37MP0001663_abnormal_digestive_system1.72581558
38MP0005636_abnormal_mineral_homeostasis1.69720299
39MP0010329_abnormal_lipoprotein_level1.66750971
40MP0009379_abnormal_foot_pigmentation1.63017605
41MP0001756_abnormal_urination1.62698343
42MP0005220_abnormal_exocrine_pancreas1.59060420
43MP0005084_abnormal_gallbladder_morpholo1.55700478
44MP0003868_abnormal_feces_composition1.48777456
45MP0000613_abnormal_salivary_gland1.46902180
46MP0000477_abnormal_intestine_morphology1.44687318
47MP0010678_abnormal_skin_adnexa1.44478570
48MP0005166_decreased_susceptibility_to1.39980272
49MP0000537_abnormal_urethra_morphology1.35701846
50MP0005332_abnormal_amino_acid1.33498290
51MP0000762_abnormal_tongue_morphology1.27777122
52MP0002136_abnormal_kidney_physiology1.26530224
53MP0005310_abnormal_salivary_gland1.25972262
54MP0003183_abnormal_peptide_metabolism1.23801580
55MP0002796_impaired_skin_barrier1.23537993
56MP0000470_abnormal_stomach_morphology1.23439933
57MP0001849_ear_inflammation1.22095720
58MP0003879_abnormal_hair_cell1.18769223
59MP0005058_abnormal_lysosome_morphology1.18111327
60MP0010386_abnormal_urinary_bladder1.17981129
61MP0000538_abnormal_urinary_bladder1.16126336
62MP0005257_abnormal_intraocular_pressure1.15277477
63MP0003011_delayed_dark_adaptation1.15044680
64MP0002234_abnormal_pharynx_morphology1.14310325
65MP0005670_abnormal_white_adipose1.11865339
66MP0005167_abnormal_blood-brain_barrier1.09919666
67MP0002166_altered_tumor_susceptibility1.08561280
68MP0001764_abnormal_homeostasis1.07485408
69MP0010352_gastrointestinal_tract_polyps1.01535442
70MP0001188_hyperpigmentation1.01415728
71MP0002254_reproductive_system_inflammat0.99776750
72MP0000566_synostosis0.96014113
73MP0000609_abnormal_liver_physiology0.93227174
74MP0001485_abnormal_pinna_reflex0.92989808
75MP0002928_abnormal_bile_duct0.89782703
76MP0000465_gastrointestinal_hemorrhage0.88603728
77MP0008961_abnormal_basal_metabolism0.86747273
78MP0003705_abnormal_hypodermis_morpholog0.85808655
79MP0005448_abnormal_energy_balance0.82162076
80MP0003045_fibrosis0.81543155
81MP0002876_abnormal_thyroid_physiology0.80462446
82MP0001958_emphysema0.80417123
83MP0003453_abnormal_keratinocyte_physiol0.79096244
84MP0001845_abnormal_inflammatory_respons0.77585250
85MP0005584_abnormal_enzyme/coenzyme_acti0.77489825
86MP0003191_abnormal_cellular_cholesterol0.77172281
87MP0002971_abnormal_brown_adipose0.76263815
88MP0001944_abnormal_pancreas_morphology0.74826362
89MP0002009_preneoplasia0.74548646
90MP0005666_abnormal_adipose_tissue0.74317717
91MP0000230_abnormal_systemic_arterial0.73521522
92MP0004270_analgesia0.73208510
93MP0001881_abnormal_mammary_gland0.71596008
94MP0000681_abnormal_thyroid_gland0.71285076
95MP0009780_abnormal_chondrocyte_physiolo0.70800234
96MP0005499_abnormal_olfactory_system0.70417483
97MP0005394_taste/olfaction_phenotype0.70417483
98MP0004947_skin_inflammation0.68828011
99MP0000377_abnormal_hair_follicle0.68519570
100MP0002693_abnormal_pancreas_physiology0.68250245
101MP0003806_abnormal_nucleotide_metabolis0.67779826
102MP0000383_abnormal_hair_follicle0.66511166
103MP0002006_tumorigenesis0.66188641
104MP0008872_abnormal_physiological_respon0.66090605
105MP0003718_maternal_effect0.66025321
106MP0003724_increased_susceptibility_to0.65838024
107MP0009115_abnormal_fat_cell0.65554141
108MP0005319_abnormal_enzyme/_coenzyme0.65515446
109MP0001216_abnormal_epidermal_layer0.65408825
110MP0004272_abnormal_basement_membrane0.64159900
111MP0009053_abnormal_anal_canal0.63268514
112MP0009642_abnormal_blood_homeostasis0.62549794
113MP0002233_abnormal_nose_morphology0.62160265
114MP0002822_catalepsy0.62076660
115MP0009785_altered_susceptibility_to0.61505136
116MP0005501_abnormal_skin_physiology0.61234882
117MP0001501_abnormal_sleep_pattern0.60555868
118MP0002896_abnormal_bone_mineralization0.59984248
119MP0003186_abnormal_redox_activity0.59297979
120MP0003890_abnormal_embryonic-extraembry0.58966966
121MP0000163_abnormal_cartilage_morphology0.58489097
122MP0000627_abnormal_mammary_gland0.58387280
123MP0000467_abnormal_esophagus_morphology0.58175857
124MP0005535_abnormal_body_temperature0.58152877
125MP0005451_abnormal_body_composition0.55696440
126MP0003938_abnormal_ear_development0.55509569
127MP0002118_abnormal_lipid_homeostasis0.55387349
128MP0003953_abnormal_hormone_level0.54692080
129MP0005165_increased_susceptibility_to0.54689611
130MP0003329_amyloid_beta_deposits0.54674333
131MP0008469_abnormal_protein_level0.54220502
132MP0005408_hypopigmentation0.53436290
133MP0002932_abnormal_joint_morphology0.52875731
134MP0004858_abnormal_nervous_system0.51337207
135MP0003941_abnormal_skin_development0.50781105
136MP0000049_abnormal_middle_ear0.48162750
137MP0003566_abnormal_cell_adhesion0.44663137

Predicted human phenotypes

RankGene SetZ-score
1Hyperactive renin-angiotensin system (HP:0000841)6.98103233
2Abnormality of chloride homeostasis (HP:0011422)5.67104208
3Abnormality of proline metabolism (HP:0010907)5.66465390
4Hydroxyprolinuria (HP:0003080)5.66465390
5Metabolic alkalosis (HP:0200114)4.96777504
6Gout (HP:0001997)4.42516993
7Chronic diarrhea (HP:0002028)4.37784583
8Fat malabsorption (HP:0002630)4.26159249
9Hyperaldosteronism (HP:0000859)4.13753053
10Abnormality of renin-angiotensin system (HP:0000847)4.03788017
11Flat acetabular roof (HP:0003180)4.02794834
12Abnormality of the vitamin B12 metabolism (HP:0004341)4.02553868
13Renal salt wasting (HP:0000127)4.02284709
14Congenital sensorineural hearing impairment (HP:0008527)4.01937606
15Ileus (HP:0002595)4.00509712
16Hypobetalipoproteinemia (HP:0003563)3.77609635
17Abnormality of vitamin B metabolism (HP:0004340)3.74064965
18Abnormality of monocarboxylic acid metabolism (HP:0010996)3.73188937
19Systemic lupus erythematosus (HP:0002725)3.52179792
20Hypokalemic alkalosis (HP:0001949)3.51468636
21Abnormality of the distal phalanx of the thumb (HP:0009617)3.48340282
22Abdominal distention (HP:0003270)3.41649482
23Symphalangism affecting the phalanges of the hand (HP:0009773)3.40553628
24Posterior subcapsular cataract (HP:0007787)3.26658196
25Abnormality of vitamin metabolism (HP:0100508)3.24124592
26Right ventricular cardiomyopathy (HP:0011663)3.12390574
27Acanthocytosis (HP:0001927)3.12100500
28Ventricular fibrillation (HP:0001663)3.10998510
29Malnutrition (HP:0004395)3.10974656
30Confusion (HP:0001289)3.10355763
31Hyperparathyroidism (HP:0000843)3.09560743
32Neonatal short-limb short stature (HP:0008921)3.08248223
33Alkalosis (HP:0001948)3.08006722
34Abnormality of small intestinal villus morphology (HP:0011472)3.03250485
35Villous atrophy (HP:0011473)3.03250485
36Abnormal hemoglobin (HP:0011902)2.99866793
37Dehydration (HP:0001944)2.99111029
38Flat capital femoral epiphysis (HP:0003370)2.97241480
39Pigmentary retinal degeneration (HP:0001146)2.95279970
40Abnormal cartilage morphology (HP:0002763)2.94228429
41Increased purine levels (HP:0004368)2.92537014
42Hyperuricemia (HP:0002149)2.92537014
43Glycosuria (HP:0003076)2.86933485
44Abnormality of urine glucose concentration (HP:0011016)2.86933485
45Decreased circulating renin level (HP:0003351)2.84878246
46Hypomagnesemia (HP:0002917)2.81991049
47Abnormality of renal excretion (HP:0011036)2.80243647
48Wide cranial sutures (HP:0010537)2.78618886
49Hemorrhage of the eye (HP:0011885)2.78574646
50Abnormality of carpal bone ossification (HP:0006257)2.77671759
51Hyperammonemia (HP:0001987)2.76585347
52Abnormality of magnesium homeostasis (HP:0004921)2.72741532
53Increased circulating renin level (HP:0000848)2.72396958
54Abnormal tarsal ossification (HP:0008369)2.71713231
55Shawl scrotum (HP:0000049)2.69363926
56Steatorrhea (HP:0002570)2.68339591
57Hyponatremia (HP:0002902)2.68126875
58Hypokalemia (HP:0002900)2.67223657
59Cheilitis (HP:0100825)2.64138034
60Abnormality of purine metabolism (HP:0004352)2.58233710
61Nausea (HP:0002018)2.56988356
62Hyperglycinuria (HP:0003108)2.56320745
63Hyperphosphatemia (HP:0002905)2.53777037
64Abnormality of the 1st metacarpal (HP:0010009)2.52729652
65Abnormality of glutamine family amino acid metabolism (HP:0010902)2.51819115
66Nephrolithiasis (HP:0000787)2.51081355
67Hyperphosphaturia (HP:0003109)2.50613539
68Tetany (HP:0001281)2.48850098
69Abnormality of serine family amino acid metabolism (HP:0010894)2.47331937
70Abnormality of glycine metabolism (HP:0010895)2.47331937
71Widely patent fontanelles and sutures (HP:0004492)2.46634594
72Abnormality of potassium homeostasis (HP:0011042)2.43765996
73Vacuolated lymphocytes (HP:0001922)2.43321315
74Cupped ribs (HP:0000887)2.43156955
75Short middle phalanx of finger (HP:0005819)2.42988255
76Xanthomatosis (HP:0000991)2.41828409
77Proximal tubulopathy (HP:0000114)2.41513431
78Micronodular cirrhosis (HP:0001413)2.40958544
79Intrahepatic cholestasis (HP:0001406)2.40349324
80Visceral angiomatosis (HP:0100761)2.40328584
81Flattened epiphyses (HP:0003071)2.38772378
82Abnormal urine phosphate concentration (HP:0012599)2.37714063
83Renal tubular acidosis (HP:0001947)2.36791610
84Tubulointerstitial fibrosis (HP:0005576)2.35186550
85Partial duplication of thumb phalanx (HP:0009944)2.33595416
86Abnormality of the phalanges of the hallux (HP:0010057)2.32794761
87Pustule (HP:0200039)2.32299610
88Focal segmental glomerulosclerosis (HP:0000097)2.32197256
89Pili torti (HP:0003777)2.31953498
90Growth hormone excess (HP:0000845)2.27044782
91Subcapsular cataract (HP:0000523)2.26177834
92Eczematoid dermatitis (HP:0000976)2.25792113
93Abnormal urine output (HP:0012590)2.24756156
94Glomerulonephritis (HP:0000099)2.23306748
95Chronic bronchitis (HP:0004469)2.22958097
96Abnormality of sodium homeostasis (HP:0010931)2.22905481
97Spinal cord compression (HP:0002176)2.22294697
98Abnormal hair laboratory examination (HP:0003328)2.20968232
99Conjugated hyperbilirubinemia (HP:0002908)2.20314708
100Megaloblastic anemia (HP:0001889)2.20251626
101Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.19736911
102Bilateral microphthalmos (HP:0007633)2.18395721
103Hyperkalemia (HP:0002153)2.17843425
104Interstitial pulmonary disease (HP:0006530)2.16063105
105Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.13994862
106Fragile nails (HP:0001808)2.13960428
107Hemangiomatosis (HP:0007461)2.13700460
108Polyuria (HP:0000103)2.13490935
109Enlarged epiphyses (HP:0010580)2.11589489
110Hypotension (HP:0002615)2.07333562
111Metabolic acidosis (HP:0001942)2.06227153
112Large earlobe (HP:0009748)2.04192978
113Aplasia/Hypoplasia of the sacrum (HP:0008517)2.03321510
114Protuberant abdomen (HP:0001538)2.03062144
115Abnormal hand bone ossification (HP:0010660)2.02133093
116Abnormality of dicarboxylic acid metabolism (HP:0010995)2.01529944
117Dicarboxylic aciduria (HP:0003215)2.01529944
118Delayed epiphyseal ossification (HP:0002663)2.00607081
119Tracheal stenosis (HP:0002777)2.00152467
120Tachypnea (HP:0002789)1.99938121
121Curly hair (HP:0002212)1.99867909
122Premature loss of primary teeth (HP:0006323)1.99320106
123Adrenal overactivity (HP:0002717)1.97757328
124Potter facies (HP:0002009)1.97714706
125Facial shape deformation (HP:0011334)1.97714706
126Abnormality of nucleobase metabolism (HP:0010932)1.97540713
127Hypophosphatemia (HP:0002148)1.96678877
128Glomerulosclerosis (HP:0000096)1.95824467
129Cerebral palsy (HP:0100021)1.94888305
130Nephritis (HP:0000123)1.92850635
131Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.92229651
132Hypoplasia of the uterus (HP:0000013)1.91700801
133Abnormality of renal resorption (HP:0011038)1.90623836
134Abnormal biliary tract morphology (HP:0012440)1.90553205
135Thin bony cortex (HP:0002753)1.89823149
136Abnormal glucose tolerance (HP:0001952)1.89260260
137Abnormal pancreas size (HP:0012094)1.88974130
138Hypolipoproteinemia (HP:0010981)1.88831258
139Hyperinsulinemic hypoglycemia (HP:0000825)1.88609609
140Reduced antithrombin III activity (HP:0001976)1.88413772
141Symptomatic seizures (HP:0011145)1.87684808
142Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.87226973
143Abnormality of the costochondral junction (HP:0000919)1.86666610
144Biliary tract neoplasm (HP:0100574)1.85848603
145Bone pain (HP:0002653)1.85683655
146Abnormality of the middle phalanges of the toes (HP:0010183)1.85672222
147Pancreatitis (HP:0001733)1.85222993
148Abnormal ossification of hand bones (HP:0005921)1.84840329
149Abnormality of complement system (HP:0005339)1.84321875
150Multiple lipomas (HP:0001012)1.84050399

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK37.90686884
2ACVR1B5.53379780
3FRK3.61552130
4EPHB23.29346542
5MST1R3.21673459
6LMTK23.21595425
7WNK42.91839478
8MST42.75563691
9GRK62.62331982
10MAP2K22.59015727
11GRK12.49272952
12ERN12.47246996
13TRIB32.40206063
14CDK122.34211869
15OXSR12.17873419
16PRKG22.17871920
17MAP3K102.13833044
18PIK3CA2.10578983
19STK392.06398391
20EPHA21.92434565
21FGFR41.92383732
22RIPK11.91597603
23MAP3K121.87207405
24PBK1.73220342
25GRK51.72308555
26TESK21.62328260
27MAP3K21.61288321
28NME11.53266217
29TTK1.50671894
30TGFBR21.49190087
31EPHA31.40532084
32WNK31.37210611
33STK241.36885998
34BLK1.32055775
35BCKDK1.29524768
36WNK11.25969948
37MAP2K61.21751313
38MAPK151.21086906
39STK38L1.20155958
40MATK1.19293605
41PKN21.19116910
42NUAK11.15737973
43MET1.15519658
44SIK11.10899406
45PTK21.10611086
46MYLK1.09744599
47ADRBK21.09156324
48SMG11.08987321
49MAPKAPK31.05630353
50PRKCI1.00803109
51STK101.00197372
52TYK20.96721876
53ERBB20.94861246
54FGFR30.94776495
55PAK40.94015406
56INSRR0.91028116
57AKT30.89081066
58GRK70.85927972
59IRAK30.84119814
60NEK60.80214152
61PTK60.78526970
62EEF2K0.71170286
63PRPF4B0.71111752
64MAP3K140.69881362
65MAP3K30.68083900
66FER0.67543588
67SCYL20.66079622
68PIK3CG0.63460227
69RET0.61643686
70PDK10.58070224
71LRRK20.57980969
72TAOK10.57468937
73CSK0.56239458
74PDK20.55833292
75MAP2K10.55765985
76MAPK110.55752233
77RPS6KB20.54145471
78DDR20.52859637
79DYRK1B0.52423293
80EPHB10.52341799
81AURKB0.51784813
82LATS10.51060119
83TLK10.48792074
84RIPK40.47247160
85YES10.46939947
86KSR20.46846195
87HIPK20.46678008
88BMPR20.46230491
89MAP3K70.44860703
90NLK0.43638667
91RPS6KA20.43315495
92MOS0.42088187
93PRKAA20.41621581
94MAP4K10.41452665
95ADRBK10.41450089
96PRKCZ0.41417301
97MAP3K10.41233533
98NTRK10.40052283
99PRKD20.39201557
100IRAK10.38194764
101ICK0.38173468
102PRKACG0.37327075
103CAMK2G0.34907903
104CDC42BPA0.32540099
105MAPK70.32516100
106DMPK0.32504029
107PDGFRA0.32314960
108ABL20.31370608
109MAPKAPK20.31031963
110ILK0.30842784
111BCR0.29593092
112CSF1R0.28797347
113JAK10.27947156
114PRKCD0.27712184
115EIF2AK20.27212215
116CDK60.26248057
117MARK20.25531664
118CDK70.24559359
119GSK3A0.24109130
120PRKCQ0.23527189
121DAPK20.23225234
122MUSK0.22902370
123CAMK2D0.22817656
124PRKCA0.22245840
125AKT20.22140148
126JAK20.20550121
127FYN0.20407168
128BMX0.20387517
129EPHA40.19732545
130IKBKE0.19159312
131MAP3K110.18963683
132PDGFRB0.18918078
133TIE10.18796151
134CHUK0.17936986
135PDPK10.17757692
136PRKAA10.17105443
137SRC0.16819040
138PAK30.16415871
139CAMK40.15867268
140IGF1R0.15645429
141TESK10.14996684
142TBK10.14868504
143ZAP700.13531937
144MELK0.13441471
145PASK0.12823681
146PLK10.12756437

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.96675768
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.82840686
3Mineral absorption_Homo sapiens_hsa049783.44786394
4Fat digestion and absorption_Homo sapiens_hsa049752.70941121
5Pentose and glucuronate interconversions_Homo sapiens_hsa000402.65011374
6Protein digestion and absorption_Homo sapiens_hsa049742.55866718
7Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.32569602
8Pancreatic secretion_Homo sapiens_hsa049722.30808292
9Arginine biosynthesis_Homo sapiens_hsa002202.28246071
10Fructose and mannose metabolism_Homo sapiens_hsa000512.22400676
11Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.16383493
12Other glycan degradation_Homo sapiens_hsa005112.11307480
13Folate biosynthesis_Homo sapiens_hsa007901.99181051
14Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.88240098
15Renin-angiotensin system_Homo sapiens_hsa046141.86495439
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.86380583
17Vitamin digestion and absorption_Homo sapiens_hsa049771.83293615
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.79540403
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.77637949
20Galactose metabolism_Homo sapiens_hsa000521.76216828
21Arachidonic acid metabolism_Homo sapiens_hsa005901.73265164
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.71975091
23Bile secretion_Homo sapiens_hsa049761.71597158
24Tryptophan metabolism_Homo sapiens_hsa003801.68354943
25Oxidative phosphorylation_Homo sapiens_hsa001901.64161531
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.62463053
27Histidine metabolism_Homo sapiens_hsa003401.62308256
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.59901884
29Glutathione metabolism_Homo sapiens_hsa004801.51082041
30Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.49412775
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.48450895
32Linoleic acid metabolism_Homo sapiens_hsa005911.44492392
33Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.41104809
34Starch and sucrose metabolism_Homo sapiens_hsa005001.32368903
35Butanoate metabolism_Homo sapiens_hsa006501.27187512
36Glycerolipid metabolism_Homo sapiens_hsa005611.25927030
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.25874650
38Chemical carcinogenesis_Homo sapiens_hsa052041.23588677
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.22268735
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.19088855
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17977929
42Tight junction_Homo sapiens_hsa045301.15214652
43Phenylalanine metabolism_Homo sapiens_hsa003601.14599972
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.09791794
45Protein export_Homo sapiens_hsa030601.03792095
46Cyanoamino acid metabolism_Homo sapiens_hsa004601.03419561
47Parkinsons disease_Homo sapiens_hsa050121.02053055
48Fatty acid degradation_Homo sapiens_hsa000710.93660516
49Leukocyte transendothelial migration_Homo sapiens_hsa046700.93499152
50Alzheimers disease_Homo sapiens_hsa050100.92683836
51Sphingolipid metabolism_Homo sapiens_hsa006000.90885019
52Propanoate metabolism_Homo sapiens_hsa006400.90254205
53Thyroid hormone synthesis_Homo sapiens_hsa049180.89754497
54Arginine and proline metabolism_Homo sapiens_hsa003300.89301956
55Nitrogen metabolism_Homo sapiens_hsa009100.83014485
56Asthma_Homo sapiens_hsa053100.79829519
57Pentose phosphate pathway_Homo sapiens_hsa000300.77525244
58Vibrio cholerae infection_Homo sapiens_hsa051100.76223925
59Hepatitis C_Homo sapiens_hsa051600.75737868
60Selenocompound metabolism_Homo sapiens_hsa004500.73577852
61beta-Alanine metabolism_Homo sapiens_hsa004100.73068142
62Tyrosine metabolism_Homo sapiens_hsa003500.69350293
63Fatty acid metabolism_Homo sapiens_hsa012120.69298325
64Ether lipid metabolism_Homo sapiens_hsa005650.68977491
65Retinol metabolism_Homo sapiens_hsa008300.66762632
66Peroxisome_Homo sapiens_hsa041460.63601381
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62950375
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.62562306
69Caffeine metabolism_Homo sapiens_hsa002320.61609538
70Sulfur relay system_Homo sapiens_hsa041220.60394322
71Huntingtons disease_Homo sapiens_hsa050160.60153499
72Metabolic pathways_Homo sapiens_hsa011000.58799552
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.58631894
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57073170
75Bladder cancer_Homo sapiens_hsa052190.56598476
76Gastric acid secretion_Homo sapiens_hsa049710.56034364
77Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54613896
78Autoimmune thyroid disease_Homo sapiens_hsa053200.52134947
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.51260720
80Pyruvate metabolism_Homo sapiens_hsa006200.51094633
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50641921
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.47570154
83Allograft rejection_Homo sapiens_hsa053300.47242337
84Insulin resistance_Homo sapiens_hsa049310.47184226
85Steroid biosynthesis_Homo sapiens_hsa001000.45917175
86ABC transporters_Homo sapiens_hsa020100.45001769
87Fatty acid biosynthesis_Homo sapiens_hsa000610.44315846
88Cardiac muscle contraction_Homo sapiens_hsa042600.44309977
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.43745941
90Lysosome_Homo sapiens_hsa041420.43034401
91Staphylococcus aureus infection_Homo sapiens_hsa051500.40088944
92Choline metabolism in cancer_Homo sapiens_hsa052310.38739323
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38625806
94Collecting duct acid secretion_Homo sapiens_hsa049660.38520801
95Vitamin B6 metabolism_Homo sapiens_hsa007500.38360104
96PPAR signaling pathway_Homo sapiens_hsa033200.37988761
97Graft-versus-host disease_Homo sapiens_hsa053320.37695684
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37481175
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37097933
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.35395925
101Renin secretion_Homo sapiens_hsa049240.35092084
102Type I diabetes mellitus_Homo sapiens_hsa049400.34097210
103Inositol phosphate metabolism_Homo sapiens_hsa005620.31863369
104Influenza A_Homo sapiens_hsa051640.31861156
105Salivary secretion_Homo sapiens_hsa049700.29897860
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.28737897
107RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.28684400
108Adherens junction_Homo sapiens_hsa045200.27695331
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.26174425
110Thyroid cancer_Homo sapiens_hsa052160.25408349
111Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.23983550
112Intestinal immune network for IgA production_Homo sapiens_hsa046720.20568525
113Primary bile acid biosynthesis_Homo sapiens_hsa001200.19011525
114Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.18923299
115Ribosome_Homo sapiens_hsa030100.18825922
116Carbon metabolism_Homo sapiens_hsa012000.18715856
117Biosynthesis of amino acids_Homo sapiens_hsa012300.17786062
118Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.17549061
119Taste transduction_Homo sapiens_hsa047420.16447075
120Pertussis_Homo sapiens_hsa051330.15336603
121Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.14706680
122Antigen processing and presentation_Homo sapiens_hsa046120.14478599
123AMPK signaling pathway_Homo sapiens_hsa041520.14133161
124Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.12930015
125Glucagon signaling pathway_Homo sapiens_hsa049220.11022759
126Fatty acid elongation_Homo sapiens_hsa000620.09299070
127Leishmaniasis_Homo sapiens_hsa051400.08279698
128Cocaine addiction_Homo sapiens_hsa050300.06502790
129Insulin secretion_Homo sapiens_hsa049110.06245630
130N-Glycan biosynthesis_Homo sapiens_hsa005100.05478193
131GnRH signaling pathway_Homo sapiens_hsa049120.03070943

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