PRR18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)7.06270649
2cellular potassium ion homeostasis (GO:0030007)6.15278638
3axon ensheathment (GO:0008366)6.07274115
4ensheathment of neurons (GO:0007272)6.07274115
5myelination (GO:0042552)6.05808638
6fatty acid elongation (GO:0030497)5.96191140
7sodium ion export (GO:0071436)5.65837927
8long-chain fatty acid biosynthetic process (GO:0042759)5.11746062
9neurotransmitter secretion (GO:0007269)5.08979272
10regulation of synaptic vesicle transport (GO:1902803)5.04698551
11potassium ion homeostasis (GO:0055075)4.80968353
12myelin maintenance (GO:0043217)4.62610505
13potassium ion import (GO:0010107)4.52142120
14negative regulation of neurotransmitter transport (GO:0051589)4.42508699
15locomotory exploration behavior (GO:0035641)4.42249192
16negative regulation of neurotransmitter secretion (GO:0046929)4.33510162
17L-amino acid import (GO:0043092)4.28539452
18oligodendrocyte differentiation (GO:0048709)4.25671740
19cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.22608335
20establishment of mitochondrion localization (GO:0051654)4.15916017
21neurotransmitter transport (GO:0006836)4.13370130
22regulation of long-term neuronal synaptic plasticity (GO:0048169)4.12321671
23negative regulation of protein localization to cell surface (GO:2000009)4.08495700
24presynaptic membrane organization (GO:0097090)4.07410068
25positive regulation of synapse maturation (GO:0090129)3.95706186
26regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.93971417
27regulation of neurotransmitter levels (GO:0001505)3.88585304
28apical protein localization (GO:0045176)3.87600407
29regulation of collateral sprouting (GO:0048670)3.81458607
30regulation of ARF protein signal transduction (GO:0032012)3.79935538
31postsynaptic membrane organization (GO:0001941)3.79596357
32regulation of synaptic plasticity (GO:0048167)3.76723945
33presynaptic membrane assembly (GO:0097105)3.74707895
34glycerophospholipid catabolic process (GO:0046475)3.74637659
35asymmetric protein localization (GO:0008105)3.70752549
36cellular sodium ion homeostasis (GO:0006883)3.70322194
37exploration behavior (GO:0035640)3.70258429
38neuronal action potential propagation (GO:0019227)3.68949274
39adult walking behavior (GO:0007628)3.67626938
40neuron cell-cell adhesion (GO:0007158)3.66550043
41response to methylmercury (GO:0051597)3.63414129
42regulation of glutamate receptor signaling pathway (GO:1900449)3.62998206
43synaptic transmission, glutamatergic (GO:0035249)3.62840502
44negative regulation of inclusion body assembly (GO:0090084)3.62100035
45creatine metabolic process (GO:0006600)3.60665164
46regulation of neurotransmitter secretion (GO:0046928)3.60385529
47acidic amino acid transport (GO:0015800)3.59552456
48eye photoreceptor cell differentiation (GO:0001754)3.58283398
49photoreceptor cell differentiation (GO:0046530)3.58283398
50astrocyte development (GO:0014002)3.57325880
51regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.56991318
52positive regulation of oligodendrocyte differentiation (GO:0048714)3.55291675
53cell communication by electrical coupling (GO:0010644)3.53570617
54positive regulation of membrane potential (GO:0045838)3.53265007
55neuromuscular process controlling balance (GO:0050885)3.52764980
56transmission of nerve impulse (GO:0019226)3.50183745
57long-term synaptic potentiation (GO:0060291)3.46337770
58regulation of neurotransmitter transport (GO:0051588)3.46051581
59negative regulation of dendrite morphogenesis (GO:0050774)3.45737604
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.42415326
61substantia nigra development (GO:0021762)3.41402483
62positive regulation of dendritic spine development (GO:0060999)3.38568013
63neurotransmitter-gated ion channel clustering (GO:0072578)3.34460350
64cholesterol biosynthetic process (GO:0006695)3.34172076
65regulation of synapse structural plasticity (GO:0051823)3.32240643
66import into cell (GO:0098657)3.29254080
67positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.28886233
68peptidyl-tyrosine autophosphorylation (GO:0038083)3.27462002
69glycine transport (GO:0015816)3.24608747
70L-glutamate transport (GO:0015813)3.21138731
71membrane tubulation (GO:0097320)3.21043086
72synaptic vesicle endocytosis (GO:0048488)3.20828841
73dendritic spine morphogenesis (GO:0060997)3.20218895
74amino acid import (GO:0043090)3.19865629
75regulation of postsynaptic membrane potential (GO:0060078)3.17412993
76negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.16886659
77regulation of dendritic spine development (GO:0060998)3.16633124
78cerebellar Purkinje cell differentiation (GO:0021702)3.13812951
79regulation of vesicle fusion (GO:0031338)3.12687950
80neurotransmitter uptake (GO:0001504)3.12277970
81synaptic vesicle maturation (GO:0016188)3.09561478
82long-term memory (GO:0007616)3.09506738
83regulation of synaptic transmission (GO:0050804)3.07460883
84detection of calcium ion (GO:0005513)3.07132146
85neuronal ion channel clustering (GO:0045161)3.06281218
86regulation of synapse maturation (GO:0090128)3.04072398
87negative regulation of axonogenesis (GO:0050771)3.02948386
88myelination in peripheral nervous system (GO:0022011)3.02619443
89peripheral nervous system axon ensheathment (GO:0032292)3.02619443
90neuron recognition (GO:0008038)3.01697688
91long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.01611895
92neuron remodeling (GO:0016322)3.00883653
93positive regulation of neurotransmitter secretion (GO:0001956)3.00519783
94positive regulation of neurotransmitter transport (GO:0051590)3.00496461
95protein palmitoylation (GO:0018345)2.99481200
96regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.97204761
97positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.96878129
98cerebral cortex radially oriented cell migration (GO:0021799)2.96215967
99magnesium ion transport (GO:0015693)2.94205623
100limb bud formation (GO:0060174)2.93736485
101sterol biosynthetic process (GO:0016126)2.90190681
102neuromuscular process controlling posture (GO:0050884)2.89492867
103gamma-aminobutyric acid transport (GO:0015812)2.87647909
104nerve growth factor signaling pathway (GO:0038180)2.87391408
105positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.87190941
106positive regulation of Rap GTPase activity (GO:0032854)2.86705436
107ionotropic glutamate receptor signaling pathway (GO:0035235)2.86404353
108axon development (GO:0061564)2.84803388
109regulation of synaptic transmission, glutamatergic (GO:0051966)2.84033945
110negative regulation of synaptic transmission, GABAergic (GO:0032229)2.83689293
111cerebellar granule cell differentiation (GO:0021707)2.82063218
112layer formation in cerebral cortex (GO:0021819)2.81238269
113long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.81018639
114synaptic transmission (GO:0007268)2.80604648
115membrane depolarization (GO:0051899)2.79869864
116cytoskeletal anchoring at plasma membrane (GO:0007016)2.79591829
117positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.75282556
118positive regulation of action potential (GO:0045760)2.72403286
119amyloid precursor protein metabolic process (GO:0042982)2.71064321
120synaptic vesicle exocytosis (GO:0016079)2.70639322
121auditory behavior (GO:0031223)2.69143454
122regulation of synaptic vesicle exocytosis (GO:2000300)2.68656656
123regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.66778778
124response to lipoprotein particle (GO:0055094)2.66595672
125isoprenoid biosynthetic process (GO:0008299)2.65694138
126dendrite morphogenesis (GO:0048813)2.63610847
127response to redox state (GO:0051775)2.63500371
128mechanosensory behavior (GO:0007638)2.62402564
129regulation of dopamine metabolic process (GO:0042053)2.62165046
130regulation of catecholamine metabolic process (GO:0042069)2.62165046
131adult locomotory behavior (GO:0008344)2.62014711
132regulation of lipoprotein metabolic process (GO:0050746)2.60415260
133membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.60370623
134gamma-aminobutyric acid signaling pathway (GO:0007214)2.59678738
135protein localization to synapse (GO:0035418)2.59636353
136mating behavior (GO:0007617)2.58269077
137glutamate receptor signaling pathway (GO:0007215)2.58235156
138regulation of short-term neuronal synaptic plasticity (GO:0048172)2.57855512
139fatty-acyl-CoA biosynthetic process (GO:0046949)2.55365748
140axonal fasciculation (GO:0007413)2.54387225
141cellular response to monoamine stimulus (GO:0071868)2.52892447
142cellular response to catecholamine stimulus (GO:0071870)2.52892447
143negative regulation of axon extension (GO:0030517)2.52829911
144peptidyl-cysteine modification (GO:0018198)2.52746548
145regulation of dendritic spine morphogenesis (GO:0061001)2.52332244
146regulation of neuronal synaptic plasticity (GO:0048168)2.52213849
147vocalization behavior (GO:0071625)2.51066991
148glutamate secretion (GO:0014047)2.48630326
149neuron-neuron synaptic transmission (GO:0007270)2.47895320
150regulation of voltage-gated calcium channel activity (GO:1901385)2.47113241
151peripheral nervous system development (GO:0007422)2.46628053
152detection of temperature stimulus involved in sensory perception (GO:0050961)2.45145610
153detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.45145610
154glycosylceramide metabolic process (GO:0006677)2.44772860
155positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.44265174
156central nervous system myelination (GO:0022010)10.6456127
157axon ensheathment in central nervous system (GO:0032291)10.6456127

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.95629768
2GBX2_23144817_ChIP-Seq_PC3_Human3.31464296
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.78473832
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.77097215
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.72294072
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.71349475
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.48432177
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.48432177
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.47559832
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.41372834
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36738220
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32848369
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.30420803
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.29266937
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.27343432
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.24121881
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.19857227
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.19660506
19* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.18575366
20SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.17805033
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.13218063
22TAF15_26573619_Chip-Seq_HEK293_Human2.11806701
23AR_21572438_ChIP-Seq_LNCaP_Human2.03895628
24DROSHA_22980978_ChIP-Seq_HELA_Human2.03022791
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.98362600
26RARB_27405468_Chip-Seq_BRAIN_Mouse1.78572278
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75314657
28REST_21632747_ChIP-Seq_MESCs_Mouse1.73666753
29OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.73431067
30RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.70012754
31RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.68818367
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.62657059
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.62313319
34TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.61009454
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.60964835
36TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56846989
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.55913697
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55289111
39ESR2_21235772_ChIP-Seq_MCF-7_Human1.53575930
40* KDM2B_26808549_Chip-Seq_K562_Human1.53411245
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51628899
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51326038
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50142276
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.45181288
45SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45083835
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.42149912
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42074450
48ER_23166858_ChIP-Seq_MCF-7_Human1.41866065
49EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.41552570
50PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40622910
51CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.38506865
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36156609
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.35595326
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30721314
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30172821
56* P300_19829295_ChIP-Seq_ESCs_Human1.29293628
57TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29078203
58STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27817842
59TET1_21490601_ChIP-Seq_MESCs_Mouse1.27189623
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.26092057
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26013416
62GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25770192
63CTCF_27219007_Chip-Seq_Bcells_Human1.24260520
64POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22963240
65P53_22127205_ChIP-Seq_FIBROBLAST_Human1.22559867
66VDR_22108803_ChIP-Seq_LS180_Human1.22272433
67ZFP281_27345836_Chip-Seq_ESCs_Mouse1.21179948
68ERG_21242973_ChIP-ChIP_JURKAT_Human1.19635933
69SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16073426
70SMAD4_21799915_ChIP-Seq_A2780_Human1.15198579
71* RING1B_27294783_Chip-Seq_ESCs_Mouse1.14456590
72CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13833844
73SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.13735533
74STAT3_23295773_ChIP-Seq_U87_Human1.13680603
75PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.13211407
76RNF2_27304074_Chip-Seq_NSC_Mouse1.13183065
77* LXR_22292898_ChIP-Seq_THP-1_Human1.12307350
78KDM2B_26808549_Chip-Seq_SUP-B15_Human1.12130012
79AR_19668381_ChIP-Seq_PC3_Human1.11563812
80RING1B_27294783_Chip-Seq_NPCs_Mouse1.10376875
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09969467
82MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.08836588
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.05556263
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05329868
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03867356
86FUS_26573619_Chip-Seq_HEK293_Human1.03769153
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02446422
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02209756
89SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02100524
90SMC4_20622854_ChIP-Seq_HELA_Human1.02061741
91ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.01759228
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00484202
93OCT4_19829295_ChIP-Seq_ESCs_Human1.00207494
94NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99370212
95ARNT_22903824_ChIP-Seq_MCF-7_Human0.99002754
96PRDM14_20953172_ChIP-Seq_ESCs_Human0.98463205
97IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98413206
98LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97859275
99GATA1_26923725_Chip-Seq_HPCs_Mouse0.97321734
100NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96907109
101LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96649520
102SOX2_21211035_ChIP-Seq_LN229_Gbm0.96483413
103GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95638861
104TCF4_23295773_ChIP-Seq_U87_Human0.95408968
105TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94875342
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.94835082
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.94835082
108NANOG_18555785_Chip-Seq_ESCs_Mouse0.94184108
109AHR_22903824_ChIP-Seq_MCF-7_Human0.94147986
110CMYC_18555785_Chip-Seq_ESCs_Mouse0.93269182
111TAL1_26923725_Chip-Seq_HPCs_Mouse0.91684680
112SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.91500326
113PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.91172842
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.90584722
115EP300_21415370_ChIP-Seq_HL-1_Mouse0.89701330
116TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89343822
117YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89275797
118EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88625109
119CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.88559991
120SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88269715
121ZNF217_24962896_ChIP-Seq_MCF-7_Human0.88252737
122DPY_21335234_ChIP-Seq_ESCs_Mouse0.88215480
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87634849
124TRIM28_21343339_ChIP-Seq_HEK293_Human0.85494913
125ZNF274_21170338_ChIP-Seq_K562_Hela0.85250935
126SRY_22984422_ChIP-ChIP_TESTIS_Rat0.85221772
127OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.85206219
128* RUNX2_22187159_ChIP-Seq_PCA_Human0.84991897
129SUZ12_18555785_Chip-Seq_ESCs_Mouse0.83743150
130PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83546229
131DNAJC2_21179169_ChIP-ChIP_NT2_Human0.83512928
132MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.83112274
133BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82494102
134ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.82124645
135SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.81665585
136SMAD4_21741376_ChIP-Seq_HESCs_Human0.79262204
137KLF4_19829295_ChIP-Seq_ESCs_Human0.76402126
138SMAD3_21741376_ChIP-Seq_ESCs_Human0.75451646
139SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.75310573
140MYC_19915707_ChIP-ChIP_AK7_Human0.75136595
141EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.74982313
142EGR1_19032775_ChIP-ChIP_M12_Human0.74130567
143CREB1_26743006_Chip-Seq_LNCaP_Human0.73764147
144* SMAD4_21741376_ChIP-Seq_ESCs_Human0.73325759
145TP53_23651856_ChIP-Seq_MEFs_Mouse0.71159629
146TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.70791454

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.77163718
2MP0000920_abnormal_myelination4.55026280
3MP0004270_analgesia3.73083232
4MP0004859_abnormal_synaptic_plasticity3.72679581
5MP0001486_abnormal_startle_reflex2.88526929
6MP0002272_abnormal_nervous_system2.80684453
7MP0003635_abnormal_synaptic_transmissio2.78870663
8MP0002064_seizures2.78349929
9MP0003690_abnormal_glial_cell2.77218300
10MP0005423_abnormal_somatic_nervous2.64878349
11MP0003329_amyloid_beta_deposits2.64695955
12MP0003950_abnormal_plasma_membrane2.64351670
13MP0004885_abnormal_endolymph2.62915204
14MP0009745_abnormal_behavioral_response2.52554781
15MP0001529_abnormal_vocalization2.47221284
16MP0004742_abnormal_vestibular_system2.46911306
17MP0009046_muscle_twitch2.45259521
18MP0001905_abnormal_dopamine_level2.28768380
19MP0000778_abnormal_nervous_system2.24578046
20MP0004142_abnormal_muscle_tone2.23909041
21MP0002734_abnormal_mechanical_nocicepti2.17720132
22MP0003136_yellow_coat_color2.15678408
23MP0003634_abnormal_glial_cell2.15630148
24MP0002063_abnormal_learning/memory/cond2.14609993
25MP0002572_abnormal_emotion/affect_behav2.01414695
26MP0001984_abnormal_olfaction1.98420003
27MP0003879_abnormal_hair_cell1.95304941
28MP0005171_absent_coat_pigmentation1.89134893
29MP0001485_abnormal_pinna_reflex1.88237142
30MP0005409_darkened_coat_color1.79761796
31MP0001440_abnormal_grooming_behavior1.76880742
32MP0002229_neurodegeneration1.72414242
33MP0008569_lethality_at_weaning1.69601044
34MP0003787_abnormal_imprinting1.68602848
35MP0001968_abnormal_touch/_nociception1.67436540
36MP0001970_abnormal_pain_threshold1.67025042
37MP0000955_abnormal_spinal_cord1.65225327
38MP0003632_abnormal_nervous_system1.62746747
39MP0002067_abnormal_sensory_capabilities1.59428585
40MP0002822_catalepsy1.55562584
41MP0005167_abnormal_blood-brain_barrier1.55049155
42MP0002733_abnormal_thermal_nociception1.52006193
43MP0002882_abnormal_neuron_morphology1.51278887
44MP0003631_nervous_system_phenotype1.48478168
45MP0004924_abnormal_behavior1.44768629
46MP0005386_behavior/neurological_phenoty1.44768629
47MP0003633_abnormal_nervous_system1.44763337
48MP0002066_abnormal_motor_capabilities/c1.44762204
49MP0005410_abnormal_fertilization1.43905401
50MP0002638_abnormal_pupillary_reflex1.38845021
51MP0004043_abnormal_pH_regulation1.37257518
52MP0001501_abnormal_sleep_pattern1.34209256
53MP0002736_abnormal_nociception_after1.29969674
54MP0000604_amyloidosis1.29027037
55MP0005551_abnormal_eye_electrophysiolog1.28532847
56MP0001963_abnormal_hearing_physiology1.25329542
57MP0008260_abnormal_autophagy1.22459362
58MP0000462_abnormal_digestive_system1.21628927
59MP0002735_abnormal_chemical_nociception1.20978023
60MP0002184_abnormal_innervation1.19580077
61MP0002557_abnormal_social/conspecific_i1.14951307
62MP0010678_abnormal_skin_adnexa1.13217240
63MP0004145_abnormal_muscle_electrophysio1.12716450
64MP0002752_abnormal_somatic_nervous1.12613970
65MP0004381_abnormal_hair_follicle1.06602496
66MP0005451_abnormal_body_composition1.05791573
67MP0001299_abnormal_eye_distance/1.05285629
68MP0002152_abnormal_brain_morphology1.02494639
69MP0003123_paternal_imprinting1.02407949
70MP0004811_abnormal_neuron_physiology1.02255510
71MP0000747_muscle_weakness0.99929207
72MP0001502_abnormal_circadian_rhythm0.99835873
73MP0005623_abnormal_meninges_morphology0.97316759
74MP0003122_maternal_imprinting0.96910479
75MP0001177_atelectasis0.96489492
76MP0005646_abnormal_pituitary_gland0.96313979
77MP0002909_abnormal_adrenal_gland0.95626915
78MP0006276_abnormal_autonomic_nervous0.95246279
79MP0005645_abnormal_hypothalamus_physiol0.89978447
80MP0000383_abnormal_hair_follicle0.85217602
81MP0004134_abnormal_chest_morphology0.84340101
82MP0003938_abnormal_ear_development0.82603746
83MP0004147_increased_porphyrin_level0.80560398
84MP0000026_abnormal_inner_ear0.80492341
85MP0001346_abnormal_lacrimal_gland0.79862737
86MP0003137_abnormal_impulse_conducting0.78728107
87MP0005195_abnormal_posterior_eye0.77294871
88MP0005535_abnormal_body_temperature0.74116573
89MP0000631_abnormal_neuroendocrine_gland0.73368484
90MP0001348_abnormal_lacrimal_gland0.72174313
91MP0003283_abnormal_digestive_organ0.72131721
92MP0006072_abnormal_retinal_apoptosis0.70036356
93MP0008877_abnormal_DNA_methylation0.69027804
94MP0002090_abnormal_vision0.68075614
95MP0005253_abnormal_eye_physiology0.68025223
96MP0002653_abnormal_ependyma_morphology0.66749506
97MP0001851_eye_inflammation0.65830169
98MP0008872_abnormal_physiological_respon0.65106946
99MP0004133_heterotaxia0.64444815
100MP0000566_synostosis0.64055687
101MP0001986_abnormal_taste_sensitivity0.63286192
102MP0005166_decreased_susceptibility_to0.61074171
103MP0002069_abnormal_eating/drinking_beha0.60436056
104MP0003075_altered_response_to0.59843098
105MP0000762_abnormal_tongue_morphology0.59754536
106MP0008874_decreased_physiological_sensi0.59691373
107MP0004085_abnormal_heartbeat0.59292968
108MP0001943_abnormal_respiration0.58423912
109MP0010386_abnormal_urinary_bladder0.58198890
110MP0003937_abnormal_limbs/digits/tail_de0.58078675
111MP0000579_abnormal_nail_morphology0.57671545
112MP0009780_abnormal_chondrocyte_physiolo0.57452445
113MP0000647_abnormal_sebaceous_gland0.57313963
114MP0003861_abnormal_nervous_system0.57222675
115MP0003172_abnormal_lysosome_physiology0.56046172
116MP0000751_myopathy0.55428567
117MP0000639_abnormal_adrenal_gland0.53904667
118MP0001765_abnormal_ion_homeostasis0.53228448
119MP0010769_abnormal_survival0.52361183
120MP0005058_abnormal_lysosome_morphology0.51339815
121MP0004858_abnormal_nervous_system0.51284134
122MP0010770_preweaning_lethality0.49152995
123MP0002082_postnatal_lethality0.49152995
124MP0010768_mortality/aging0.48691743
125MP0003956_abnormal_body_size0.48671459
126MP0003045_fibrosis0.48022974
127MP0001731_abnormal_postnatal_growth0.44337285
128MP0002089_abnormal_postnatal_growth/wei0.43437615
129MP0002873_normal_phenotype0.43315678

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)6.22500367
2Degeneration of the lateral corticospinal tracts (HP:0002314)6.02258826
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.02258826
4Myokymia (HP:0002411)4.83434667
5Abnormality of the corticospinal tract (HP:0002492)4.72319471
6Diplopia (HP:0000651)4.66762560
7Abnormality of binocular vision (HP:0011514)4.66762560
8Cerebral inclusion bodies (HP:0100314)4.60166616
9Febrile seizures (HP:0002373)4.56499194
10Peripheral hypomyelination (HP:0007182)4.53408523
11Supranuclear gaze palsy (HP:0000605)4.33239185
12Sensory axonal neuropathy (HP:0003390)4.05408127
13Spastic gait (HP:0002064)3.93148734
14Parakeratosis (HP:0001036)3.86101325
15Onion bulb formation (HP:0003383)3.80344357
16Ankle clonus (HP:0011448)3.66170297
17Dysmetria (HP:0001310)3.64859705
18Focal motor seizures (HP:0011153)3.56592430
19Insidious onset (HP:0003587)3.49988670
20Termporal pattern (HP:0011008)3.49988670
21Cerebral hypomyelination (HP:0006808)3.46545941
22Abnormal eating behavior (HP:0100738)3.46259513
23Generalized tonic-clonic seizures (HP:0002069)3.44787440
24Intention tremor (HP:0002080)3.42104196
25Visual hallucinations (HP:0002367)3.34842892
26Torticollis (HP:0000473)3.28046019
27Obstructive sleep apnea (HP:0002870)3.27350610
28Postural instability (HP:0002172)3.18348763
29Abnormal auditory evoked potentials (HP:0006958)3.17386657
30Papilledema (HP:0001085)3.15708183
31Alacrima (HP:0000522)3.14853687
32Absence seizures (HP:0002121)3.10800090
33Scanning speech (HP:0002168)3.09037967
34Abnormal respiratory motile cilium morphology (HP:0005938)3.05103127
35Abnormal respiratory epithelium morphology (HP:0012253)3.05103127
36Hemiplegia (HP:0002301)3.04601266
37Abnormal respiratory motile cilium physiology (HP:0012261)3.02297188
38Tetraplegia (HP:0002445)2.86724437
39Rhinitis (HP:0012384)2.85239161
40Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.80140997
41Status epilepticus (HP:0002133)2.76626985
42Depression (HP:0000716)2.76570534
43Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.75129063
44Focal dystonia (HP:0004373)2.73866818
45Urinary urgency (HP:0000012)2.73746589
46Mutism (HP:0002300)2.70033083
47Slow saccadic eye movements (HP:0000514)2.68970458
48Action tremor (HP:0002345)2.68126037
49Annular pancreas (HP:0001734)2.62647912
50Focal seizures (HP:0007359)2.60723846
51Sleep apnea (HP:0010535)2.60049507
52Craniofacial dystonia (HP:0012179)2.59340161
53Delusions (HP:0000746)2.58830026
54Clumsiness (HP:0002312)2.54280246
55Megalencephaly (HP:0001355)2.53954771
56Lower limb muscle weakness (HP:0007340)2.53472303
57Rigidity (HP:0002063)2.53013041
58Leukodystrophy (HP:0002415)2.52668904
59Impaired vibration sensation in the lower limbs (HP:0002166)2.51956955
60Retinal dysplasia (HP:0007973)2.50373154
61Broad-based gait (HP:0002136)2.49135240
62Aplasia involving bones of the extremities (HP:0009825)2.46985754
63Aplasia involving bones of the upper limbs (HP:0009823)2.46985754
64Aplasia of the phalanges of the hand (HP:0009802)2.46985754
65Bradykinesia (HP:0002067)2.46441098
66Abnormality of the periventricular white matter (HP:0002518)2.45988824
67Thickened helices (HP:0000391)2.44786762
68Akinesia (HP:0002304)2.44326827
69Segmental peripheral demyelination/remyelination (HP:0003481)2.42820756
70Insomnia (HP:0100785)2.41771285
71Decreased lacrimation (HP:0000633)2.40882221
72Absent septum pellucidum (HP:0001331)2.40766415
73Morphological abnormality of the inner ear (HP:0011390)2.39719076
74Increased circulating renin level (HP:0000848)2.35462501
75Anteriorly placed anus (HP:0001545)2.34533495
76Hypoplastic pelvis (HP:0008839)2.29715065
77Spastic tetraparesis (HP:0001285)2.29307352
78CNS hypomyelination (HP:0003429)2.28074748
79Atonic seizures (HP:0010819)2.26956422
80Epileptiform EEG discharges (HP:0011182)2.26702460
81Clonus (HP:0002169)2.22758621
82Apathy (HP:0000741)2.22460626
83Rapidly progressive (HP:0003678)2.22455244
84Metabolic alkalosis (HP:0200114)2.21963361
85Epileptic encephalopathy (HP:0200134)2.20874785
86Pheochromocytoma (HP:0002666)2.19334718
87Progressive cerebellar ataxia (HP:0002073)2.14175544
88Split foot (HP:0001839)2.13595891
89Spastic paraparesis (HP:0002313)2.13563208
90Cerebral hemorrhage (HP:0001342)2.13431271
91Dysdiadochokinesis (HP:0002075)2.13355064
92Humeroradial synostosis (HP:0003041)2.11198659
93Synostosis involving the elbow (HP:0003938)2.11198659
94Poor eye contact (HP:0000817)2.09990398
95Foot dorsiflexor weakness (HP:0009027)2.09467995
96Poor speech (HP:0002465)2.09328137
97Bowel incontinence (HP:0002607)2.07416566
98Urinary bladder sphincter dysfunction (HP:0002839)2.07109513
99Neuronal loss in central nervous system (HP:0002529)2.06300680
100Stridor (HP:0010307)2.06000584
101Abnormality of the septum pellucidum (HP:0007375)2.05719511
102Morphological abnormality of the pyramidal tract (HP:0002062)2.04568558
103Limb dystonia (HP:0002451)2.03636139
104Impaired vibratory sensation (HP:0002495)2.02068092
105Axonal loss (HP:0003447)2.01187423
106Memory impairment (HP:0002354)2.01058488
107Impaired smooth pursuit (HP:0007772)2.00643609
108Coronal craniosynostosis (HP:0004440)1.99525369
109Diminished motivation (HP:0000745)1.98216981
110Hypomagnesemia (HP:0002917)1.98186838
111Autoamputation (HP:0001218)1.97012725
112Urinary incontinence (HP:0000020)1.95869150
113Amblyopia (HP:0000646)1.95660711
114EEG with generalized epileptiform discharges (HP:0011198)1.95494302
115Bronchomalacia (HP:0002780)1.94924035
116Ventricular fibrillation (HP:0001663)1.93798254
117Absent/shortened dynein arms (HP:0200106)1.93411952
118Dynein arm defect of respiratory motile cilia (HP:0012255)1.93411952
119Anxiety (HP:0000739)1.93174326
120Progressive inability to walk (HP:0002505)1.93148775
121Abnormality of the foot musculature (HP:0001436)1.92125896
122Decreased motor nerve conduction velocity (HP:0003431)1.91809813
123Hypokalemic alkalosis (HP:0001949)1.90540614
124Bronchiectasis (HP:0002110)1.90141320
125Abnormal large intestine physiology (HP:0012700)1.90140237
126Infantile muscular hypotonia (HP:0008947)1.90100906
127Bundle branch block (HP:0011710)1.89155667
128Gaze-evoked nystagmus (HP:0000640)1.88805557
129Dialeptic seizures (HP:0011146)1.88608119
130Fetal akinesia sequence (HP:0001989)1.88065999
131Abnormality of the phalanges of the 2nd finger (HP:0009541)1.87807253
132Abnormality of glycolysis (HP:0004366)1.87170826
133Increased serum pyruvate (HP:0003542)1.87170826
134Lower limb asymmetry (HP:0100559)1.87091448
135Generalized myoclonic seizures (HP:0002123)1.86287213
136Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.85976210
137Hammertoe (HP:0001765)1.85175336
138Hemiparesis (HP:0001269)1.84106133
139Abnormality of the middle phalanges of the toes (HP:0010183)1.81059961
140Septo-optic dysplasia (HP:0100842)1.79704705
141Truncal ataxia (HP:0002078)1.79682189
142Abnormal ciliary motility (HP:0012262)1.79631578
143Neuroendocrine neoplasm (HP:0100634)1.79623315
144Distal sensory impairment (HP:0002936)1.79434373
145Abnormality of saccadic eye movements (HP:0000570)1.78054591
146Choreoathetosis (HP:0001266)1.77978708

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.13265028
2OXSR13.98771024
3UHMK12.66611913
4CDK192.56973413
5BCR2.52218598
6CAMKK12.50160071
7EPHA42.48326668
8PKN12.47879638
9EPHB12.47333619
10MAPKAPK52.23315051
11RIPK42.10318059
12MARK12.07761676
13WNK42.03537241
14WNK12.02712223
15PNCK2.02684789
16PRPF4B1.99000080
17LIMK11.94639312
18TNIK1.89678044
19FGFR21.85094244
20NTRK11.81558700
21PAK61.75255968
22CAMK2B1.65921493
23MET1.63623632
24CSNK1G31.61140532
25CSNK1A1L1.58764145
26PBK1.54562331
27NEK61.42525150
28ROCK21.42419406
29CASK1.38960667
30NTRK21.37551469
31NTRK31.36748021
32MAP3K91.35715087
33CSNK1G21.35182937
34FGR1.33807733
35ICK1.29917151
36CAMK11.29300978
37SIK21.27759777
38CSNK1G11.26237534
39SGK4941.24678653
40SGK2231.24678653
41RIPK11.24602717
42CAMK2D1.23147329
43CLK11.22079253
44CDK51.19427662
45ALK1.18182632
46LATS21.15538297
47TYRO31.12897795
48DAPK11.09610021
49SGK21.08019569
50MARK21.07630916
51CAMK2G1.05053205
52CDK141.01875383
53PHKG11.01724004
54PHKG21.01724004
55PAK31.00911418
56CAMK2A0.99334537
57TESK20.98586291
58MINK10.97384527
59MUSK0.96696850
60CDK150.96498062
61CDK180.93436480
62DYRK20.92481103
63PRKD30.91992797
64ARAF0.91916084
65MAPK120.91704843
66SGK30.90065668
67STK380.87667810
68CDK11A0.86649792
69CAMKK20.85290005
70MAPK130.82477552
71MAPK150.81740258
72MAP3K40.77292795
73KSR20.76896374
74PRKD10.75409195
75PINK10.74089114
76TNK20.71212784
77PRKCQ0.68316244
78PDPK10.66578187
79PRKCE0.65342166
80STK110.64881879
81PRKCH0.64811817
82RPS6KA30.64413223
83PRKCZ0.63371348
84FYN0.62469757
85FES0.60230131
86MST40.59796432
87MAP3K20.59766290
88IRAK20.59152235
89MAP3K130.57589150
90ROCK10.51283034
91DAPK20.50555055
92RAF10.50490851
93PRKG10.49264444
94BRSK10.48760175
95MAP2K70.48382776
96DYRK1A0.48234939
97CSNK1D0.46777250
98MAP3K10.46638465
99CAMK40.45624178
100GRK50.45125975
101MAP3K110.44776111
102TRPM70.44065900
103TESK10.43644316
104CSNK1A10.43198880
105ERBB40.42223960
106BRAF0.41587308
107FGFR30.40725665
108BMPR1B0.40690701
109PDK10.40251986
110DMPK0.40240270
111PRKCG0.39589741
112PRKCA0.38969605
113MAPK100.38761651
114GSK3A0.38746129
115PRKACB0.38167309
116ERBB20.38077368
117CAMK1G0.37052461
118DAPK30.36833148
119RET0.36794481
120BMPR20.36325743
121PTK2B0.35901874
122LMTK20.35670981
123GRK70.35248214
124RPS6KA50.34395068
125PLK20.33968564
126MAP2K40.33834061
127JAK10.33685909
128CCNB10.32994158
129SGK10.32944424
130DDR20.31890439
131PRKACA0.31850544
132ADRBK20.30847178
133PDGFRB0.29525961
134MAP2K20.29194409
135PRKCB0.28000166

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.90819695
2Steroid biosynthesis_Homo sapiens_hsa001003.13044845
3Fatty acid elongation_Homo sapiens_hsa000623.10450757
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.75071975
5Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.67232090
6Nitrogen metabolism_Homo sapiens_hsa009102.65337099
7Ether lipid metabolism_Homo sapiens_hsa005652.50977578
8GABAergic synapse_Homo sapiens_hsa047272.28946205
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.28317482
10Glutamatergic synapse_Homo sapiens_hsa047242.11659909
11Nicotine addiction_Homo sapiens_hsa050332.02819558
12Morphine addiction_Homo sapiens_hsa050321.87709978
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.84725016
14Axon guidance_Homo sapiens_hsa043601.82077413
15Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.76941499
16Serotonergic synapse_Homo sapiens_hsa047261.66769540
17Circadian entrainment_Homo sapiens_hsa047131.62713570
18Vitamin B6 metabolism_Homo sapiens_hsa007501.59958085
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.59705984
20beta-Alanine metabolism_Homo sapiens_hsa004101.59029677
21Synaptic vesicle cycle_Homo sapiens_hsa047211.57702443
22Oxidative phosphorylation_Homo sapiens_hsa001901.49588466
23Long-term depression_Homo sapiens_hsa047301.47321195
24Cocaine addiction_Homo sapiens_hsa050301.43902893
25Salivary secretion_Homo sapiens_hsa049701.39283876
26Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.35254890
27Gastric acid secretion_Homo sapiens_hsa049711.31776927
28Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.31695715
29Dopaminergic synapse_Homo sapiens_hsa047281.29950790
30Sphingolipid metabolism_Homo sapiens_hsa006001.28383458
31Olfactory transduction_Homo sapiens_hsa047401.26263348
32Butanoate metabolism_Homo sapiens_hsa006501.20986385
33Bile secretion_Homo sapiens_hsa049761.18318531
34Linoleic acid metabolism_Homo sapiens_hsa005911.17531716
35Parkinsons disease_Homo sapiens_hsa050121.16706566
36Amphetamine addiction_Homo sapiens_hsa050311.16102716
37Cholinergic synapse_Homo sapiens_hsa047251.15325922
38Alzheimers disease_Homo sapiens_hsa050101.15324142
39Cardiac muscle contraction_Homo sapiens_hsa042601.14146705
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.13867374
41Sulfur metabolism_Homo sapiens_hsa009201.13594436
42Collecting duct acid secretion_Homo sapiens_hsa049661.09600916
43Histidine metabolism_Homo sapiens_hsa003401.06641391
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.05322689
45Renin secretion_Homo sapiens_hsa049241.04889822
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04624849
47Taste transduction_Homo sapiens_hsa047421.04119824
48Long-term potentiation_Homo sapiens_hsa047201.03062093
49Renal cell carcinoma_Homo sapiens_hsa052111.01021379
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.98923640
51Glioma_Homo sapiens_hsa052140.95763299
52Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94145480
53Sphingolipid signaling pathway_Homo sapiens_hsa040710.93530607
54Carbohydrate digestion and absorption_Homo sapiens_hsa049730.93045675
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.92039486
56Gap junction_Homo sapiens_hsa045400.91052452
57Vibrio cholerae infection_Homo sapiens_hsa051100.89922377
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.89313753
59Phototransduction_Homo sapiens_hsa047440.88583994
60Thyroid hormone synthesis_Homo sapiens_hsa049180.88028937
61Insulin secretion_Homo sapiens_hsa049110.87855005
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.87358186
63Tight junction_Homo sapiens_hsa045300.85711206
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84969936
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.84867044
66Dorso-ventral axis formation_Homo sapiens_hsa043200.83278584
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.82809075
68ErbB signaling pathway_Homo sapiens_hsa040120.81641254
69Arginine and proline metabolism_Homo sapiens_hsa003300.81157985
70cAMP signaling pathway_Homo sapiens_hsa040240.80407869
71Oxytocin signaling pathway_Homo sapiens_hsa049210.79722330
72Ras signaling pathway_Homo sapiens_hsa040140.79005281
73Calcium signaling pathway_Homo sapiens_hsa040200.77869578
74Endocytosis_Homo sapiens_hsa041440.77314339
75Pancreatic secretion_Homo sapiens_hsa049720.77153659
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75829536
77Inositol phosphate metabolism_Homo sapiens_hsa005620.75756726
78Ovarian steroidogenesis_Homo sapiens_hsa049130.74919645
79Oocyte meiosis_Homo sapiens_hsa041140.74196927
80Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73326728
81Protein export_Homo sapiens_hsa030600.72643891
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.69911989
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69692402
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.67769066
85Phenylalanine metabolism_Homo sapiens_hsa003600.67076594
86Type II diabetes mellitus_Homo sapiens_hsa049300.66810147
87Rap1 signaling pathway_Homo sapiens_hsa040150.65670636
88Circadian rhythm_Homo sapiens_hsa047100.64500467
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62895173
90GnRH signaling pathway_Homo sapiens_hsa049120.60274160
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60148110
92Melanogenesis_Homo sapiens_hsa049160.58595787
93Mineral absorption_Homo sapiens_hsa049780.55123634
94Arginine biosynthesis_Homo sapiens_hsa002200.54309912
95Hedgehog signaling pathway_Homo sapiens_hsa043400.52611524
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51943405
97Fatty acid biosynthesis_Homo sapiens_hsa000610.51881438
98Rheumatoid arthritis_Homo sapiens_hsa053230.51505506
99ABC transporters_Homo sapiens_hsa020100.49016910
100Huntingtons disease_Homo sapiens_hsa050160.48431572
101VEGF signaling pathway_Homo sapiens_hsa043700.48425798
102Prion diseases_Homo sapiens_hsa050200.48015912
103MAPK signaling pathway_Homo sapiens_hsa040100.47178951
104Choline metabolism in cancer_Homo sapiens_hsa052310.46916977
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46767731
106Glucagon signaling pathway_Homo sapiens_hsa049220.45435264
107Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44969364
108Arachidonic acid metabolism_Homo sapiens_hsa005900.44844579
109Folate biosynthesis_Homo sapiens_hsa007900.44361575
110cGMP-PKG signaling pathway_Homo sapiens_hsa040220.41947748
111Alcoholism_Homo sapiens_hsa050340.40787441
112Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40455997
113Autoimmune thyroid disease_Homo sapiens_hsa053200.39983908
114Phagosome_Homo sapiens_hsa041450.39819399
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39411396
116Dilated cardiomyopathy_Homo sapiens_hsa054140.39338770
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38212479
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.37294308
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36055604
120Lysosome_Homo sapiens_hsa041420.35575891
121Fatty acid metabolism_Homo sapiens_hsa012120.35183061
122Estrogen signaling pathway_Homo sapiens_hsa049150.35075790
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34212927
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32498196
125mTOR signaling pathway_Homo sapiens_hsa041500.32359658
126Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26294395
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.21404899
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19086324

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