PRR3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.20358562
2behavioral response to nicotine (GO:0035095)5.08244443
3protein localization to synapse (GO:0035418)4.16399820
4establishment of mitochondrion localization (GO:0051654)3.95863459
5neural tube formation (GO:0001841)3.88797392
6negative regulation of microtubule polymerization (GO:0031115)3.87872908
7dendritic spine morphogenesis (GO:0060997)3.86784735
8pyrimidine nucleobase catabolic process (GO:0006208)3.84955270
9peptidyl-arginine omega-N-methylation (GO:0035247)3.81059875
10neuron recognition (GO:0008038)3.80295834
11L-fucose catabolic process (GO:0042355)3.77195627
12fucose catabolic process (GO:0019317)3.77195627
13L-fucose metabolic process (GO:0042354)3.77195627
14presynaptic membrane assembly (GO:0097105)3.69118257
15regulation of respiratory system process (GO:0044065)3.64089827
16mitochondrion transport along microtubule (GO:0047497)3.59608609
17establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.59608609
18cell migration in hindbrain (GO:0021535)3.59157689
19histone H2A acetylation (GO:0043968)3.55069377
20regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.43938109
21central nervous system projection neuron axonogenesis (GO:0021952)3.42511522
22mitochondrial respiratory chain complex I assembly (GO:0032981)3.41506658
23NADH dehydrogenase complex assembly (GO:0010257)3.41506658
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.41506658
25protein complex biogenesis (GO:0070271)3.39546910
26regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.38957708
27histone arginine methylation (GO:0034969)3.37844184
28positive regulation of synapse assembly (GO:0051965)3.37112041
29vocalization behavior (GO:0071625)3.34875621
30peptidyl-arginine methylation (GO:0018216)3.34691281
31peptidyl-arginine N-methylation (GO:0035246)3.34691281
32axonal fasciculation (GO:0007413)3.33697422
33response to pheromone (GO:0019236)3.31184424
34mitochondrial respiratory chain complex assembly (GO:0033108)3.26539426
35chaperone-mediated protein transport (GO:0072321)3.26532203
36presynaptic membrane organization (GO:0097090)3.25075529
37cornea development in camera-type eye (GO:0061303)3.24309296
38limb bud formation (GO:0060174)3.22838776
39transmission of nerve impulse (GO:0019226)3.21447397
40negative regulation of transcription regulatory region DNA binding (GO:2000678)3.19943331
41positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.19834936
42synaptic vesicle exocytosis (GO:0016079)3.19617189
43layer formation in cerebral cortex (GO:0021819)3.19113684
44mannosylation (GO:0097502)3.18159468
45somite development (GO:0061053)3.17279778
46kynurenine metabolic process (GO:0070189)3.15639964
47startle response (GO:0001964)3.14667324
48positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.13529875
49postsynaptic membrane organization (GO:0001941)3.11405870
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.11086513
51negative regulation of telomere maintenance (GO:0032205)3.09356835
52preassembly of GPI anchor in ER membrane (GO:0016254)3.09203505
53regulation of respiratory gaseous exchange (GO:0043576)3.07679562
54mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.06370972
55energy coupled proton transport, down electrochemical gradient (GO:0015985)3.03149617
56ATP synthesis coupled proton transport (GO:0015986)3.03149617
57regulation of short-term neuronal synaptic plasticity (GO:0048172)3.01276971
58behavioral response to ethanol (GO:0048149)3.00650011
59epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.00071495
60protein-cofactor linkage (GO:0018065)2.97055212
61detection of light stimulus involved in visual perception (GO:0050908)2.96228166
62detection of light stimulus involved in sensory perception (GO:0050962)2.96228166
63cell-cell junction maintenance (GO:0045217)2.95585421
64indole-containing compound catabolic process (GO:0042436)2.93583073
65indolalkylamine catabolic process (GO:0046218)2.93583073
66tryptophan catabolic process (GO:0006569)2.93583073
67central nervous system myelination (GO:0022010)2.93571568
68axon ensheathment in central nervous system (GO:0032291)2.93571568
69DNA double-strand break processing (GO:0000729)2.92701967
70meiotic chromosome segregation (GO:0045132)2.91544021
71detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.90198079
72recombinational repair (GO:0000725)2.88933533
73regulation of cilium movement (GO:0003352)2.88553219
74DNA replication checkpoint (GO:0000076)2.88387386
75RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.88113772
76tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.88113772
77indolalkylamine metabolic process (GO:0006586)2.87479202
78exploration behavior (GO:0035640)2.87271412
79regulation of protein kinase A signaling (GO:0010738)2.87083939
80DNA deamination (GO:0045006)2.86425044
81nonmotile primary cilium assembly (GO:0035058)2.86335654
82positive regulation of growth hormone secretion (GO:0060124)2.85220244
83double-strand break repair via homologous recombination (GO:0000724)2.84056532
84gamma-aminobutyric acid transport (GO:0015812)2.83754263
85neuronal action potential propagation (GO:0019227)2.82288592
86regulation of glutamate receptor signaling pathway (GO:1900449)2.81514713
87pseudouridine synthesis (GO:0001522)2.80589803
88alternative mRNA splicing, via spliceosome (GO:0000380)2.78941821
89locomotory exploration behavior (GO:0035641)2.78752932
90protein K6-linked ubiquitination (GO:0085020)2.78213870
91tRNA modification (GO:0006400)2.77709413
92synaptic transmission, glutamatergic (GO:0035249)2.75834438
93ubiquinone biosynthetic process (GO:0006744)2.75145250
94opioid receptor signaling pathway (GO:0038003)2.75033325
95sympathetic nervous system development (GO:0048485)2.73127717
96dendrite development (GO:0016358)2.72393080
97negative regulation of translation, ncRNA-mediated (GO:0040033)2.72060368
98regulation of translation, ncRNA-mediated (GO:0045974)2.72060368
99negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.72060368
100ubiquinone metabolic process (GO:0006743)2.71950699
101replication fork processing (GO:0031297)2.70642515
102central nervous system neuron axonogenesis (GO:0021955)2.67619832
103regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.67118110
104regulation of nuclear cell cycle DNA replication (GO:0033262)2.67016281
105synapse assembly (GO:0007416)2.66350959
106reciprocal DNA recombination (GO:0035825)2.66223091
107reciprocal meiotic recombination (GO:0007131)2.66223091
108nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.65850290
109respiratory chain complex IV assembly (GO:0008535)2.64169985
110neuron-neuron synaptic transmission (GO:0007270)2.63141300
111DNA topological change (GO:0006265)2.62556190
112base-excision repair, AP site formation (GO:0006285)2.62430158
113mRNA splice site selection (GO:0006376)2.60708431
114tRNA processing (GO:0008033)2.59597612
115dendrite morphogenesis (GO:0048813)2.59459609
116photoreceptor cell development (GO:0042461)2.59192223
117cerebellum development (GO:0021549)2.58903807
118histone H3-K9 methylation (GO:0051567)2.58877916
119exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.58670162
120nucleobase catabolic process (GO:0046113)2.58410379
121L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.58262698
122somatic diversification of immune receptors via somatic mutation (GO:0002566)2.57531673
123somatic hypermutation of immunoglobulin genes (GO:0016446)2.57531673
124epithelial cilium movement (GO:0003351)2.57219890
125intraciliary transport (GO:0042073)2.56681298
126spinal cord motor neuron differentiation (GO:0021522)2.56125271
127cerebral cortex radially oriented cell migration (GO:0021799)2.55958352
128water-soluble vitamin biosynthetic process (GO:0042364)2.55668281
129regulation of telomere maintenance (GO:0032204)2.55367731
130positive regulation of synaptic transmission, GABAergic (GO:0032230)2.54510832
131glutamate receptor signaling pathway (GO:0007215)2.53983183
132cilium morphogenesis (GO:0060271)2.53519442
133platelet dense granule organization (GO:0060155)2.53093686
134peptidyl-histidine modification (GO:0018202)2.52829868
135anterograde synaptic vesicle transport (GO:0048490)2.52283570
136ionotropic glutamate receptor signaling pathway (GO:0035235)2.50853461
137gamma-aminobutyric acid signaling pathway (GO:0007214)2.50724827
138establishment of protein localization to mitochondrial membrane (GO:0090151)2.50629140
139substrate-independent telencephalic tangential migration (GO:0021826)2.50135309
140substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.50135309
141tryptophan metabolic process (GO:0006568)2.49839813
142pyrimidine dimer repair (GO:0006290)2.49700034
143regulation of hippo signaling (GO:0035330)2.49615792
144positive regulation of oligodendrocyte differentiation (GO:0048714)2.49609255
145negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.49402433
146cytochrome complex assembly (GO:0017004)2.49343097
147positive regulation of membrane potential (GO:0045838)2.48665974
148GPI anchor metabolic process (GO:0006505)2.47679275
149centriole replication (GO:0007099)2.47456071
150synaptic transmission, cholinergic (GO:0007271)2.46950645
151regulation of dendritic spine morphogenesis (GO:0061001)2.46848882
152negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.46382580
153regulation of neuronal synaptic plasticity (GO:0048168)2.45909588
154regulation of long-term neuronal synaptic plasticity (GO:0048169)2.45275173
155protein K11-linked deubiquitination (GO:0035871)2.44196525
156regulation of glucokinase activity (GO:0033131)2.44190930
157regulation of hexokinase activity (GO:1903299)2.44190930
158protein localization to cilium (GO:0061512)2.41884575
159kidney morphogenesis (GO:0060993)2.40558604
160regulation of NFAT protein import into nucleus (GO:0051532)2.40558215
161cellular ketone body metabolic process (GO:0046950)2.40463207
162cell proliferation in forebrain (GO:0021846)2.40311212
163cilium organization (GO:0044782)2.40267962
164regulation of action potential (GO:0098900)2.39549302
165DNA damage response, detection of DNA damage (GO:0042769)2.39467914
166RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.39359316
167embryonic epithelial tube formation (GO:0001838)2.39071994
168regulation of synapse assembly (GO:0051963)2.38742474
169translesion synthesis (GO:0019985)2.38216726
170regulation of glutamate secretion (GO:0014048)2.37935900
171G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.37636620
172termination of RNA polymerase III transcription (GO:0006386)2.36291805
173transcription elongation from RNA polymerase III promoter (GO:0006385)2.36291805
174regulation of mitotic spindle checkpoint (GO:1903504)2.35401979
175regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.35401979
176neurotransmitter secretion (GO:0007269)2.35393086
177negative regulation of synaptic transmission, GABAergic (GO:0032229)2.35036174
178regulation of synaptic transmission, GABAergic (GO:0032228)2.34945904
179cullin deneddylation (GO:0010388)2.34827234
180cilium assembly (GO:0042384)2.34002347
181photoreceptor cell maintenance (GO:0045494)2.33671544
182negative regulation of neurotransmitter transport (GO:0051589)2.32227860
183head development (GO:0060322)2.30710710
184negative regulation of dendrite development (GO:2000171)2.30081895
185positive regulation of protein complex disassembly (GO:0043243)2.30057486
186hippocampus development (GO:0021766)2.29304037
187retinal ganglion cell axon guidance (GO:0031290)2.27734265
188regulation of synaptic vesicle exocytosis (GO:2000300)2.27400651
189inner mitochondrial membrane organization (GO:0007007)2.27246856
190generation of neurons (GO:0048699)2.26922029
191forebrain neuron differentiation (GO:0021879)2.25683994
192membrane hyperpolarization (GO:0060081)2.25552768
193negative regulation of RNA splicing (GO:0033119)2.24983426
194positive regulation of synapse maturation (GO:0090129)2.23777568

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.09225489
2CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.83264619
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.68654476
4IGF1R_20145208_ChIP-Seq_DFB_Human2.66824436
5GBX2_23144817_ChIP-Seq_PC3_Human2.65913168
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.57621750
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.34648093
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.29412876
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.21042522
10IRF1_19129219_ChIP-ChIP_H3396_Human2.18286139
11REST_21632747_ChIP-Seq_MESCs_Mouse2.15718998
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.09100302
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03447158
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.02078375
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.00622891
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.00383833
17VDR_23849224_ChIP-Seq_CD4+_Human1.95948664
18POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93701191
19MYC_18940864_ChIP-ChIP_HL60_Human1.93670793
20REST_18959480_ChIP-ChIP_MESCs_Mouse1.85550160
21JARID2_20075857_ChIP-Seq_MESCs_Mouse1.85457257
22SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.80787569
23BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79420673
24RNF2_27304074_Chip-Seq_NSC_Mouse1.76520909
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.74088624
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.72751272
27TAF15_26573619_Chip-Seq_HEK293_Human1.70519664
28FUS_26573619_Chip-Seq_HEK293_Human1.70420586
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.68648193
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.68408416
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.67810572
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.65507137
33* EST1_17652178_ChIP-ChIP_JURKAT_Human1.65484190
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.65446446
35EZH2_18974828_ChIP-Seq_MESCs_Mouse1.63013111
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.63013111
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62555973
38* ELK1_19687146_ChIP-ChIP_HELA_Human1.61537667
39EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.61330033
40SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.60519372
41POU5F1_16153702_ChIP-ChIP_HESCs_Human1.60022693
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.58836647
43DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.58752605
44SUZ12_27294783_Chip-Seq_ESCs_Mouse1.58426484
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55894213
46MYC_18555785_ChIP-Seq_MESCs_Mouse1.54417936
47SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54297454
48RARB_27405468_Chip-Seq_BRAIN_Mouse1.53627004
49ZFP57_27257070_Chip-Seq_ESCs_Mouse1.51966432
50TP53_22573176_ChIP-Seq_HFKS_Human1.51637591
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50993782
52FOXP3_21729870_ChIP-Seq_TREG_Human1.50003949
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.49892645
54ER_23166858_ChIP-Seq_MCF-7_Human1.49237540
55RNF2_27304074_Chip-Seq_ESCs_Mouse1.47104058
56MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.46599805
57MTF2_20144788_ChIP-Seq_MESCs_Mouse1.43813185
58ZNF274_21170338_ChIP-Seq_K562_Hela1.40746193
59TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37505200
60KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.37491725
61* E2F4_17652178_ChIP-ChIP_JURKAT_Human1.36945614
62SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.36589880
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.36116142
64EWS_26573619_Chip-Seq_HEK293_Human1.35934295
65ETS1_20019798_ChIP-Seq_JURKAT_Human1.33526310
66MYC_19079543_ChIP-ChIP_MESCs_Mouse1.32947518
67CBP_20019798_ChIP-Seq_JUKART_Human1.32550741
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32550741
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30742939
70JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.30739766
71SRF_21415370_ChIP-Seq_HL-1_Mouse1.29961447
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29289173
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29289173
74CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.24861226
75* GABP_17652178_ChIP-ChIP_JURKAT_Human1.24652386
76GABP_19822575_ChIP-Seq_HepG2_Human1.24105273
77YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22608285
78ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.22202224
79KDM5A_27292631_Chip-Seq_BREAST_Human1.21484225
80XRN2_22483619_ChIP-Seq_HELA_Human1.21076051
81PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19557219
82RING1B_27294783_Chip-Seq_ESCs_Mouse1.18925798
83UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17323797
84E2F7_22180533_ChIP-Seq_HELA_Human1.14951632
85CREB1_15753290_ChIP-ChIP_HEK293T_Human1.14734174
86FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14719781
87* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.14116410
88CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.13833132
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.13414597
90ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12108468
91CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.12070713
92POU3F1_26484290_ChIP-Seq_ESCss_Mouse1.11247351
93* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11088043
94RING1B_27294783_Chip-Seq_NPCs_Mouse1.10816889
95P300_19829295_ChIP-Seq_ESCs_Human1.09051503
96SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.08606572
97KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06734428
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06549459
99HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05887468
100STAT3_23295773_ChIP-Seq_U87_Human1.05450923
101GATA1_26923725_Chip-Seq_HPCs_Mouse1.05102317
102CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03412295
103TTF2_22483619_ChIP-Seq_HELA_Human1.02576254
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02532138
105SOX2_16153702_ChIP-ChIP_HESCs_Human1.02165443
106* ETV2_25802403_ChIP-Seq_MESCs_Mouse1.01753255
107ERA_21632823_ChIP-Seq_H3396_Human1.01573211
108DCP1A_22483619_ChIP-Seq_HELA_Human1.00713881
109PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00651660
110GATA3_21878914_ChIP-Seq_MCF-7_Human1.00457939
111SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00233015
112E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.00120933
113NCOR_22424771_ChIP-Seq_293T_Human0.99676403
114TP63_19390658_ChIP-ChIP_HaCaT_Human0.99136617
115TCF4_23295773_ChIP-Seq_U87_Human0.99041211
116VDR_22108803_ChIP-Seq_LS180_Human0.98139172
117SOX9_26525672_Chip-Seq_HEART_Mouse0.97963231
118AR_25329375_ChIP-Seq_VCAP_Human0.97798590
119YY1_21170310_ChIP-Seq_MESCs_Mouse0.97081236
120* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.97078576
121BCAT_22108803_ChIP-Seq_LS180_Human0.96999234
122BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96747180
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96722219
124FOXA1_25329375_ChIP-Seq_VCAP_Human0.96320490
125FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96320490
126RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96199353
127DROSHA_22980978_ChIP-Seq_HELA_Human0.95636933
128CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94714023
129GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.93616510
130OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93338468
131PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93194219
132SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92028713
133POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.91927316
134CIITA_25753668_ChIP-Seq_RAJI_Human0.91323812
135OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.91162386
136SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.90730596
137AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90647641
138SOX2_19829295_ChIP-Seq_ESCs_Human0.90392364
139NANOG_19829295_ChIP-Seq_ESCs_Human0.90392364
140SALL1_21062744_ChIP-ChIP_HESCs_Human0.90361048
141MYC_19030024_ChIP-ChIP_MESCs_Mouse0.90177828
142AR_20517297_ChIP-Seq_VCAP_Human0.89775454
143* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.89187601
144AR_21572438_ChIP-Seq_LNCaP_Human0.88154297
145HOXB7_26014856_ChIP-Seq_BT474_Human0.88052281
146P53_22127205_ChIP-Seq_FIBROBLAST_Human0.87624594
147* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.86989789
148PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86423008
149E2F1_17053090_ChIP-ChIP_MCF-7_Human0.86325399
150EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.86153178
151SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.85160602
152WDR5_24793694_ChIP-Seq_LNCAP_Human0.84160035
153MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.83101213

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.18982094
2MP0004859_abnormal_synaptic_plasticity3.33773999
3MP0005423_abnormal_somatic_nervous3.18992168
4MP0006292_abnormal_olfactory_placode2.95490346
5MP0001529_abnormal_vocalization2.94120020
6MP0003635_abnormal_synaptic_transmissio2.75284305
7MP0003122_maternal_imprinting2.44811328
8MP0000778_abnormal_nervous_system2.43872406
9MP0004270_analgesia2.43621617
10MP0006276_abnormal_autonomic_nervous2.32744434
11MP0001968_abnormal_touch/_nociception2.29419401
12MP0002063_abnormal_learning/memory/cond2.24182881
13MP0002064_seizures2.21449895
14MP0005645_abnormal_hypothalamus_physiol2.16478395
15MP0009745_abnormal_behavioral_response2.14924005
16MP0002572_abnormal_emotion/affect_behav2.13901204
17MP0000372_irregular_coat_pigmentation2.04474460
18MP0002734_abnormal_mechanical_nocicepti2.03766639
19MP0002736_abnormal_nociception_after1.97354007
20MP0002184_abnormal_innervation1.96586507
21MP0001905_abnormal_dopamine_level1.95637357
22MP0001486_abnormal_startle_reflex1.92679986
23MP0004142_abnormal_muscle_tone1.91555780
24MP0002272_abnormal_nervous_system1.83176362
25MP0009046_muscle_twitch1.72741003
26MP0001986_abnormal_taste_sensitivity1.70465143
27MP0002557_abnormal_social/conspecific_i1.70448866
28MP0003121_genomic_imprinting1.69023309
29MP0001984_abnormal_olfaction1.67914265
30MP0004133_heterotaxia1.66964206
31MP0002067_abnormal_sensory_capabilities1.65364316
32MP0002102_abnormal_ear_morphology1.61994595
33MP0000631_abnormal_neuroendocrine_gland1.61914088
34MP0004043_abnormal_pH_regulation1.58630008
35MP0008995_early_reproductive_senescence1.57096190
36MP0000955_abnormal_spinal_cord1.54744477
37MP0001440_abnormal_grooming_behavior1.51568363
38MP0002751_abnormal_autonomic_nervous1.49160344
39MP0006072_abnormal_retinal_apoptosis1.49137906
40MP0003136_yellow_coat_color1.48496263
41MP0002882_abnormal_neuron_morphology1.48118574
42MP0002733_abnormal_thermal_nociception1.47983758
43MP0010094_abnormal_chromosome_stability1.46642769
44MP0003283_abnormal_digestive_organ1.46601944
45MP0003861_abnormal_nervous_system1.46512757
46MP0004811_abnormal_neuron_physiology1.45886633
47MP0002638_abnormal_pupillary_reflex1.45422711
48MP0002152_abnormal_brain_morphology1.44855126
49MP0002735_abnormal_chemical_nociception1.44519607
50MP0003195_calcinosis1.42774992
51MP0008872_abnormal_physiological_respon1.41357432
52MP0004147_increased_porphyrin_level1.38735374
53MP0008057_abnormal_DNA_replication1.37845032
54MP0001970_abnormal_pain_threshold1.35264750
55MP0002160_abnormal_reproductive_system1.33445697
56MP0008877_abnormal_DNA_methylation1.32969019
57MP0004858_abnormal_nervous_system1.30920717
58MP0001188_hyperpigmentation1.30838300
59MP0003123_paternal_imprinting1.29930755
60MP0001502_abnormal_circadian_rhythm1.26854447
61MP0004924_abnormal_behavior1.26771915
62MP0005386_behavior/neurological_phenoty1.26771915
63MP0002822_catalepsy1.25591442
64MP0003938_abnormal_ear_development1.24724020
65MP0002752_abnormal_somatic_nervous1.23949728
66MP0005367_renal/urinary_system_phenotyp1.22468233
67MP0000516_abnormal_urinary_system1.22468233
68MP0005394_taste/olfaction_phenotype1.22394555
69MP0005499_abnormal_olfactory_system1.22394555
70MP0003890_abnormal_embryonic-extraembry1.21227030
71MP0002066_abnormal_motor_capabilities/c1.18533300
72MP0004885_abnormal_endolymph1.17547946
73MP0008569_lethality_at_weaning1.16255945
74MP0008932_abnormal_embryonic_tissue1.15671950
75MP0008789_abnormal_olfactory_epithelium1.15352348
76MP0002928_abnormal_bile_duct1.13280827
77MP0005551_abnormal_eye_electrophysiolog1.13208863
78MP0001485_abnormal_pinna_reflex1.12488331
79MP0002938_white_spotting1.11995711
80MP0000569_abnormal_digit_pigmentation1.11623923
81MP0004742_abnormal_vestibular_system1.09341167
82MP0005253_abnormal_eye_physiology1.07737918
83MP0002095_abnormal_skin_pigmentation1.06544112
84MP0003937_abnormal_limbs/digits/tail_de1.05900611
85MP0001501_abnormal_sleep_pattern1.05058536
86MP0000537_abnormal_urethra_morphology1.04779195
87MP0005084_abnormal_gallbladder_morpholo1.04119805
88MP0005646_abnormal_pituitary_gland1.00595135
89MP0002653_abnormal_ependyma_morphology1.00546488
90MP0008058_abnormal_DNA_repair1.00274154
91MP0003718_maternal_effect0.99515695
92MP0001324_abnormal_eye_pigmentation0.99399210
93MP0003119_abnormal_digestive_system0.97286519
94MP0000015_abnormal_ear_pigmentation0.95193904
95MP0000049_abnormal_middle_ear0.95083933
96MP0009379_abnormal_foot_pigmentation0.94252587
97MP0005389_reproductive_system_phenotype0.94101215
98MP0002876_abnormal_thyroid_physiology0.92636115
99MP0002210_abnormal_sex_determination0.92616542
100MP0001963_abnormal_hearing_physiology0.92112975
101MP0000026_abnormal_inner_ear0.90814631
102MP0003634_abnormal_glial_cell0.90554567
103MP0002229_neurodegeneration0.90219533
104MP0002163_abnormal_gland_morphology0.88976561
105MP0001929_abnormal_gametogenesis0.88530324
106MP0006035_abnormal_mitochondrial_morpho0.87644399
107MP0005409_darkened_coat_color0.87636606
108MP0005195_abnormal_posterior_eye0.86048606
109MP0003786_premature_aging0.84662244
110MP0005187_abnormal_penis_morphology0.83946669
111MP0003693_abnormal_embryo_hatching0.83617536
112MP0003787_abnormal_imprinting0.76868463
113MP0003942_abnormal_urinary_system0.76375867
114MP0005174_abnormal_tail_pigmentation0.75669536
115MP0005075_abnormal_melanosome_morpholog0.75370474
116MP0003698_abnormal_male_reproductive0.74156443
117MP0002081_perinatal_lethality0.74050966
118MP0005391_vision/eye_phenotype0.71617676
119MP0010770_preweaning_lethality0.70946435
120MP0002082_postnatal_lethality0.70946435
121MP0002234_abnormal_pharynx_morphology0.70072180
122MP0002084_abnormal_developmental_patter0.69800927
123MP0002069_abnormal_eating/drinking_beha0.69535203
124MP0005171_absent_coat_pigmentation0.67993711
125MP0010769_abnormal_survival0.67925733
126MP0002116_abnormal_craniofacial_bone0.67625270
127MP0001293_anophthalmia0.67375195

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)3.63307810
2Congenital stationary night blindness (HP:0007642)3.31238435
3Lissencephaly (HP:0001339)3.02980330
4Myokymia (HP:0002411)3.00074694
5Focal seizures (HP:0007359)2.96048609
6Patellar aplasia (HP:0006443)2.94128067
7Aplasia/Hypoplasia of the patella (HP:0006498)2.89039849
8Severe visual impairment (HP:0001141)2.86974499
9Gait imbalance (HP:0002141)2.77128360
10Chronic hepatic failure (HP:0100626)2.75512295
11Abnormality of the labia minora (HP:0012880)2.68477431
12Attenuation of retinal blood vessels (HP:0007843)2.68313288
13Abnormality of the renal medulla (HP:0100957)2.66070048
14Epileptic encephalopathy (HP:0200134)2.60044798
15Cystic liver disease (HP:0006706)2.56829384
16Abnormality of alanine metabolism (HP:0010916)2.56031638
17Hyperalaninemia (HP:0003348)2.56031638
18Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.56031638
19Hyperventilation (HP:0002883)2.52313995
20Protruding tongue (HP:0010808)2.51032644
21Limb dystonia (HP:0002451)2.45941277
22Bile duct proliferation (HP:0001408)2.43316869
23Abnormal biliary tract physiology (HP:0012439)2.43316869
24Rib fusion (HP:0000902)2.43085208
25Inability to walk (HP:0002540)2.41644422
26Retinal dysplasia (HP:0007973)2.38291696
27Atonic seizures (HP:0010819)2.37922929
28Abnormal hair whorl (HP:0010721)2.35520922
29Visual hallucinations (HP:0002367)2.34972268
30Congenital primary aphakia (HP:0007707)2.33837378
31Abnormality of the renal cortex (HP:0011035)2.31352329
32Aplasia/Hypoplasia of the uvula (HP:0010293)2.28659355
33Aplasia/Hypoplasia of the tibia (HP:0005772)2.26167906
34Abnormal drinking behavior (HP:0030082)2.25827130
35Polydipsia (HP:0001959)2.25827130
36Amyotrophic lateral sclerosis (HP:0007354)2.24591608
37Abnormal rod and cone electroretinograms (HP:0008323)2.24406637
38Supranuclear gaze palsy (HP:0000605)2.22971007
39Aplasia/Hypoplasia of the tongue (HP:0010295)2.19366224
40Progressive cerebellar ataxia (HP:0002073)2.17599121
41Polyphagia (HP:0002591)2.17149170
42Cerebellar dysplasia (HP:0007033)2.16944979
43Abnormality of the corticospinal tract (HP:0002492)2.16603893
44Spastic gait (HP:0002064)2.16504147
45Molar tooth sign on MRI (HP:0002419)2.16028864
46Abnormality of midbrain morphology (HP:0002418)2.16028864
47Absence seizures (HP:0002121)2.15938319
48Esotropia (HP:0000565)2.15297364
49Septo-optic dysplasia (HP:0100842)2.15083677
50Tubular atrophy (HP:0000092)2.13238499
51Abnormality of glycolysis (HP:0004366)2.12321434
52Increased serum pyruvate (HP:0003542)2.12321434
53Medial flaring of the eyebrow (HP:0010747)2.10821220
54Broad-based gait (HP:0002136)2.10000922
55Hypoplastic pelvis (HP:0008839)2.09639752
56Nephrogenic diabetes insipidus (HP:0009806)2.09584181
57Hemiparesis (HP:0001269)2.08887421
58Postaxial foot polydactyly (HP:0001830)2.08830536
59Specific learning disability (HP:0001328)2.08251766
60Pancreatic fibrosis (HP:0100732)2.08169523
61Dialeptic seizures (HP:0011146)2.06519342
62Poor suck (HP:0002033)2.06218978
63Occipital encephalocele (HP:0002085)2.04808540
64Increased CSF lactate (HP:0002490)2.04370282
65Genetic anticipation (HP:0003743)2.03231397
66Pendular nystagmus (HP:0012043)2.02447554
67Genital tract atresia (HP:0001827)2.02301199
68Abnormal respiratory epithelium morphology (HP:0012253)2.01030543
69Abnormal respiratory motile cilium morphology (HP:0005938)2.01030543
70Vaginal atresia (HP:0000148)2.00770980
71Mutism (HP:0002300)1.99795521
72Optic nerve hypoplasia (HP:0000609)1.98367953
73Excessive salivation (HP:0003781)1.97065627
74Drooling (HP:0002307)1.97065627
75Small hand (HP:0200055)1.95772466
76Febrile seizures (HP:0002373)1.94881862
77Abnormality of the ileum (HP:0001549)1.94113093
78Pachygyria (HP:0001302)1.93595534
79Large for gestational age (HP:0001520)1.93479205
80Meckel diverticulum (HP:0002245)1.93476039
81Abnormal number of erythroid precursors (HP:0012131)1.92432756
82Type II lissencephaly (HP:0007260)1.92336962
83Absent septum pellucidum (HP:0001331)1.91977021
84Atrophy/Degeneration involving motor neurons (HP:0007373)1.91170517
85Atelectasis (HP:0100750)1.91146654
86Progressive inability to walk (HP:0002505)1.91025003
87Abnormality of the septum pellucidum (HP:0007375)1.90954834
88Progressive microcephaly (HP:0000253)1.90473136
89Mitochondrial inheritance (HP:0001427)1.90359723
90Absent speech (HP:0001344)1.90227173
91Generalized tonic-clonic seizures (HP:0002069)1.89898559
92Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89834238
93Hypoplasia of the brainstem (HP:0002365)1.88976008
94Aplasia/Hypoplasia of the brainstem (HP:0007362)1.88976008
95Sclerocornea (HP:0000647)1.88882713
96Nephronophthisis (HP:0000090)1.87443875
97Supernumerary spleens (HP:0009799)1.86754328
98Postaxial hand polydactyly (HP:0001162)1.86739641
99Acute necrotizing encephalopathy (HP:0006965)1.86380778
100Sleep apnea (HP:0010535)1.86195671
101Cerebral hypomyelination (HP:0006808)1.84218338
102Hepatocellular necrosis (HP:0001404)1.83055376
103Colon cancer (HP:0003003)1.82789399
104Truncal ataxia (HP:0002078)1.81955221
105Abnormal ciliary motility (HP:0012262)1.81696356
106Concave nail (HP:0001598)1.81692662
107Dandy-Walker malformation (HP:0001305)1.81427822
108Abnormality of the lower motor neuron (HP:0002366)1.81051828
109Hypoplasia of the pons (HP:0012110)1.80149227
110Short tibia (HP:0005736)1.80146153
111Asplenia (HP:0001746)1.80051602
112Bony spicule pigmentary retinopathy (HP:0007737)1.79939702
113Tented upper lip vermilion (HP:0010804)1.79364021
114Bilateral microphthalmos (HP:0007633)1.78962410
115True hermaphroditism (HP:0010459)1.78915960
116Thyroid-stimulating hormone excess (HP:0002925)1.78623664
117Pancreatic cysts (HP:0001737)1.77924931
118Oligodactyly (hands) (HP:0001180)1.77713178
119Hyperthyroidism (HP:0000836)1.76647257
120Sloping forehead (HP:0000340)1.76265989
121Ectopic kidney (HP:0000086)1.75965952
122Abnormal number of incisors (HP:0011064)1.75516915
123Aganglionic megacolon (HP:0002251)1.75394147
124Chorioretinal atrophy (HP:0000533)1.75232702
125Abolished electroretinogram (ERG) (HP:0000550)1.74582711
126Abnormality of the pons (HP:0007361)1.74430385
127Partial agenesis of the corpus callosum (HP:0001338)1.74094748
128Ankle clonus (HP:0011448)1.73631509
129Morphological abnormality of the inner ear (HP:0011390)1.73404570
130Acute encephalopathy (HP:0006846)1.72709372
131Absent thumb (HP:0009777)1.72023880
132Congenital hepatic fibrosis (HP:0002612)1.71526744
133Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.71404985
134Degeneration of the lateral corticospinal tracts (HP:0002314)1.71404985
135Abnormal mitochondria in muscle tissue (HP:0008316)1.70770912
136High anterior hairline (HP:0009890)1.70690517
137Severe muscular hypotonia (HP:0006829)1.70649536
138Increased serum lactate (HP:0002151)1.70582615
139Aplasia/Hypoplasia of the spleen (HP:0010451)1.70540668
140Absent/shortened dynein arms (HP:0200106)1.70078368
141Dynein arm defect of respiratory motile cilia (HP:0012255)1.70078368
142Decreased central vision (HP:0007663)1.70063295
143Male pseudohermaphroditism (HP:0000037)1.69879560
144Aplasia/Hypoplasia of the lens (HP:0008063)1.69538625
145Progressive macrocephaly (HP:0004481)1.69424992
146Bifid tongue (HP:0010297)1.68872481
147Optic disc pallor (HP:0000543)1.68285804
148Morphological abnormality of the middle ear (HP:0008609)1.67454928
149Polyuria (HP:0000103)1.67071492
150Central scotoma (HP:0000603)1.67007853
151Hypothermia (HP:0002045)1.66452070
152Insidious onset (HP:0003587)1.65960862
153Termporal pattern (HP:0011008)1.65960862
154Gaze-evoked nystagmus (HP:0000640)1.65853905
155Optic nerve coloboma (HP:0000588)1.65775736
156Keratoconus (HP:0000563)1.65524741
157Increased corneal curvature (HP:0100692)1.65524741
158Anophthalmia (HP:0000528)1.65020718
159Fetal akinesia sequence (HP:0001989)1.64515551
160Dyschromatopsia (HP:0007641)1.64309838
161Delusions (HP:0000746)1.62780488
162Amblyopia (HP:0000646)1.61977465
163Gastroesophageal reflux (HP:0002020)1.61552363
164Preaxial hand polydactyly (HP:0001177)1.61460632
165Clumsiness (HP:0002312)1.60059380
166Anencephaly (HP:0002323)1.59982473
167Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.59891467
168Choroideremia (HP:0001139)1.59353040
169Dysdiadochokinesis (HP:0002075)1.59221950
170Birth length less than 3rd percentile (HP:0003561)1.58714276

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.68724934
2FRK4.60896181
3TNIK4.38311751
4TLK13.57112752
5NTRK33.37534744
6MAPK133.11912051
7UHMK13.02800218
8PNCK2.98804726
9STK162.71523686
10ADRBK22.65931494
11MAP4K22.52377638
12ZAK2.51089141
13DYRK22.47024607
14ACVR1B2.36310456
15BUB12.21897039
16NUAK12.18845535
17NTRK22.17065194
18EPHA42.08664912
19MAP2K71.98824975
20WNK41.98482455
21MAP3K91.93550216
22MINK11.88948520
23MAP3K121.88721976
24MAP3K41.84736913
25GRK11.65963138
26TRIM281.64238480
27VRK21.63683695
28SIK21.63549123
29CDK191.53233285
30PINK11.50172979
31CSNK1A1L1.48453906
32CSNK1G31.47222049
33SIK31.44949760
34TSSK61.44793423
35INSRR1.38106314
36CSNK1G21.36886425
37IRAK21.31766221
38BCR1.28701554
39TAOK31.25202077
40DAPK21.24226089
41YES11.19926528
42VRK11.19340048
43LIMK11.17886601
44CAMKK11.17628985
45KSR11.15499919
46PASK1.13642694
47PLK41.12260752
48ERBB31.11065988
49PLK31.09691649
50STK391.08537271
51WNK31.08198415
52SRPK11.03870330
53BCKDK0.99985244
54CSNK1G10.98551485
55CASK0.97608668
56BMPR1B0.96419494
57MARK20.95001362
58NEK20.93859264
59TGFBR10.91252201
60DAPK10.90329716
61ATR0.89095102
62CDK50.89081623
63PAK60.87848143
64MKNK10.87751445
65MAPK150.86739438
66CAMKK20.86167501
67BRSK20.86121196
68IRAK10.84837529
69FES0.82059908
70MAP2K40.81618804
71HIPK20.81384971
72PAK30.79644450
73CAMK2B0.77638765
74CCNB10.77198012
75AKT30.75233777
76TYRO30.75039972
77ADRBK10.73947275
78NME10.69723670
79CDK180.68588712
80FGFR20.67373518
81RPS6KA50.67045636
82PLK20.66910189
83EIF2AK30.66292320
84PRKCG0.65960892
85OXSR10.65511678
86CSNK1D0.65414077
87CDK11A0.65299839
88CDK140.64969912
89PKN10.64599851
90DYRK1A0.64365001
91CDK150.63946560
92AURKA0.61749355
93PLK10.61022714
94CAMK2A0.59766672
95LATS20.58486125
96PHKG10.58214081
97PHKG20.58214081
98GRK50.56954156
99TESK20.56712418
100ROCK20.55353017
101CDC70.54901755
102MAP3K60.53753542
103TAF10.52756942
104MUSK0.52655004
105DYRK30.52160784
106CSNK1E0.51768323
107CLK10.50801842
108CHEK10.50163853
109MKNK20.49168129
110SCYL20.49090001
111MAP2K60.47243221
112ATM0.46180961
113PRPF4B0.45817283
114ARAF0.45287655
115BRD40.44874817
116CAMK1D0.43724421
117PRKAA10.43211704
118CDK30.42884494
119ICK0.42880788
120PRKCI0.42598122
121FLT30.41766609
122CAMK10.41750505
123CSNK1A10.41737996
124EPHA30.41382142
125MAPK90.41333297
126WEE10.41211887
127GRK70.40451489
128CHEK20.38993735
129CDK20.38331318
130CSNK2A20.38219216
131PRKD30.37227044
132EEF2K0.37034946
133GSK3B0.37009941
134MAPKAPK50.36269550
135CDK10.35954148
136GRK60.35719951
137FGR0.35617090
138PRKCE0.35328250
139EIF2AK20.33975160
140CDK80.33870614
141PRKACA0.33861954
142TXK0.32240571
143CAMK40.32140168
144DYRK1B0.29384488
145PRKCZ0.29102126
146MAPK110.28490510

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.05853914
2Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.50692814
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.47423097
4Synaptic vesicle cycle_Homo sapiens_hsa047212.28436356
5Ribosome_Homo sapiens_hsa030102.21980659
6DNA replication_Homo sapiens_hsa030302.09958831
7Proteasome_Homo sapiens_hsa030502.09744211
8Homologous recombination_Homo sapiens_hsa034402.08161791
9Spliceosome_Homo sapiens_hsa030402.06739048
10GABAergic synapse_Homo sapiens_hsa047272.04505603
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.01872448
12RNA polymerase_Homo sapiens_hsa030202.01306310
13Selenocompound metabolism_Homo sapiens_hsa004502.00531448
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.99414821
15Oxidative phosphorylation_Homo sapiens_hsa001901.97044259
16Glutamatergic synapse_Homo sapiens_hsa047241.93626224
17Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.92743831
18Axon guidance_Homo sapiens_hsa043601.92436836
19One carbon pool by folate_Homo sapiens_hsa006701.90137626
20Nitrogen metabolism_Homo sapiens_hsa009101.90067462
21Butanoate metabolism_Homo sapiens_hsa006501.85370789
22Dopaminergic synapse_Homo sapiens_hsa047281.77446275
23Serotonergic synapse_Homo sapiens_hsa047261.76857999
24Morphine addiction_Homo sapiens_hsa050321.76167920
25Parkinsons disease_Homo sapiens_hsa050121.74608431
26Linoleic acid metabolism_Homo sapiens_hsa005911.67755927
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.65738959
28Mismatch repair_Homo sapiens_hsa034301.63082219
29Huntingtons disease_Homo sapiens_hsa050161.57329070
30Circadian entrainment_Homo sapiens_hsa047131.54358463
31Nucleotide excision repair_Homo sapiens_hsa034201.54262230
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.53112758
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.50578918
34Taste transduction_Homo sapiens_hsa047421.50149094
35mRNA surveillance pathway_Homo sapiens_hsa030151.48900208
36Amphetamine addiction_Homo sapiens_hsa050311.46113743
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.43096239
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.41938796
39Cocaine addiction_Homo sapiens_hsa050301.39612643
40Phototransduction_Homo sapiens_hsa047441.39442980
41Long-term potentiation_Homo sapiens_hsa047201.39368776
42Sulfur relay system_Homo sapiens_hsa041221.37784689
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.37354102
44Alzheimers disease_Homo sapiens_hsa050101.34714021
45RNA transport_Homo sapiens_hsa030131.34377626
46Cholinergic synapse_Homo sapiens_hsa047251.30188373
47Long-term depression_Homo sapiens_hsa047301.29724329
48Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.29248122
49Base excision repair_Homo sapiens_hsa034101.27365052
50Collecting duct acid secretion_Homo sapiens_hsa049661.26046117
51Fanconi anemia pathway_Homo sapiens_hsa034601.21926869
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20263740
53Basal transcription factors_Homo sapiens_hsa030221.16900050
54Steroid biosynthesis_Homo sapiens_hsa001001.14694577
55Oocyte meiosis_Homo sapiens_hsa041141.14243983
56Tryptophan metabolism_Homo sapiens_hsa003801.09069570
57Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08465346
58Propanoate metabolism_Homo sapiens_hsa006401.05202034
59Olfactory transduction_Homo sapiens_hsa047401.05040584
60Hedgehog signaling pathway_Homo sapiens_hsa043401.03257824
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.01862599
62Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01257597
63Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.95489333
64Cardiac muscle contraction_Homo sapiens_hsa042600.95165074
65Vibrio cholerae infection_Homo sapiens_hsa051100.93416648
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.93178882
67RNA degradation_Homo sapiens_hsa030180.92180375
68Alcoholism_Homo sapiens_hsa050340.91278401
69Colorectal cancer_Homo sapiens_hsa052100.90638165
70ErbB signaling pathway_Homo sapiens_hsa040120.90139678
71Lysine degradation_Homo sapiens_hsa003100.88476826
72Wnt signaling pathway_Homo sapiens_hsa043100.87735909
73Peroxisome_Homo sapiens_hsa041460.87493684
74Pyrimidine metabolism_Homo sapiens_hsa002400.87376646
75Insulin secretion_Homo sapiens_hsa049110.86100924
76Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.85575251
77Gap junction_Homo sapiens_hsa045400.82738664
78Type I diabetes mellitus_Homo sapiens_hsa049400.82618851
79Cell cycle_Homo sapiens_hsa041100.81757172
80Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81277932
81Oxytocin signaling pathway_Homo sapiens_hsa049210.80190621
82Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.78288081
83Aldosterone synthesis and secretion_Homo sapiens_hsa049250.77930368
84ABC transporters_Homo sapiens_hsa020100.77549794
85Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.73595578
86Caffeine metabolism_Homo sapiens_hsa002320.71563182
87Estrogen signaling pathway_Homo sapiens_hsa049150.71214627
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.70522345
89Basal cell carcinoma_Homo sapiens_hsa052170.69220771
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68707522
91Regulation of autophagy_Homo sapiens_hsa041400.68005954
92Melanogenesis_Homo sapiens_hsa049160.67633820
93Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66524676
94Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65959561
95Intestinal immune network for IgA production_Homo sapiens_hsa046720.65328337
96Purine metabolism_Homo sapiens_hsa002300.64996930
97Primary immunodeficiency_Homo sapiens_hsa053400.64232957
98GnRH signaling pathway_Homo sapiens_hsa049120.64198946
99Hippo signaling pathway_Homo sapiens_hsa043900.63135389
100Metabolic pathways_Homo sapiens_hsa011000.62954653
101Renin secretion_Homo sapiens_hsa049240.62784670
102N-Glycan biosynthesis_Homo sapiens_hsa005100.62770381
103Calcium signaling pathway_Homo sapiens_hsa040200.62545070
104Dorso-ventral axis formation_Homo sapiens_hsa043200.59700582
105MAPK signaling pathway_Homo sapiens_hsa040100.59388535
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58829747
107Salivary secretion_Homo sapiens_hsa049700.58712150
108Renal cell carcinoma_Homo sapiens_hsa052110.58518229
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57092547
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53670173
111Sphingolipid signaling pathway_Homo sapiens_hsa040710.53430938
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52622466
113Non-homologous end-joining_Homo sapiens_hsa034500.51748220
114Cysteine and methionine metabolism_Homo sapiens_hsa002700.51647875
115Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51191459
116Epstein-Barr virus infection_Homo sapiens_hsa051690.51014232
117Ras signaling pathway_Homo sapiens_hsa040140.47819739
118Steroid hormone biosynthesis_Homo sapiens_hsa001400.47261385
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46124973
120Glioma_Homo sapiens_hsa052140.45750965
121Gastric acid secretion_Homo sapiens_hsa049710.45105889
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.44372705
123Ether lipid metabolism_Homo sapiens_hsa005650.42787915
124Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.42319019
125Endometrial cancer_Homo sapiens_hsa052130.40343085
126Circadian rhythm_Homo sapiens_hsa047100.39306564
127Primary bile acid biosynthesis_Homo sapiens_hsa001200.37886005
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36943894
129Cyanoamino acid metabolism_Homo sapiens_hsa004600.36036019
130Protein export_Homo sapiens_hsa030600.35858111
131VEGF signaling pathway_Homo sapiens_hsa043700.35744955
132Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35221109
133cAMP signaling pathway_Homo sapiens_hsa040240.35220505
134Ovarian steroidogenesis_Homo sapiens_hsa049130.34751974
135Sphingolipid metabolism_Homo sapiens_hsa006000.34654761
136beta-Alanine metabolism_Homo sapiens_hsa004100.33969738
137T cell receptor signaling pathway_Homo sapiens_hsa046600.33191724
138Phospholipase D signaling pathway_Homo sapiens_hsa040720.33122135
139Choline metabolism in cancer_Homo sapiens_hsa052310.32354644
140Arachidonic acid metabolism_Homo sapiens_hsa005900.29892109
141Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28064565
142Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.26824261

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