PRR7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.60938171
2locomotory exploration behavior (GO:0035641)6.06623154
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.98716078
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.43979331
5peptidyl-arginine omega-N-methylation (GO:0035247)5.39658150
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.39112730
7layer formation in cerebral cortex (GO:0021819)5.11324154
8negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)5.11084245
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.09279813
10regulation of interferon-beta biosynthetic process (GO:0045357)5.07268030
11vocalization behavior (GO:0071625)4.89266015
12regulation of mammary gland epithelial cell proliferation (GO:0033599)4.82724305
13regulation of glutamate receptor signaling pathway (GO:1900449)4.78031911
14regulation of synapse structural plasticity (GO:0051823)4.76982019
15GDP-mannose metabolic process (GO:0019673)4.76960549
16glutamate secretion (GO:0014047)4.73883660
17NIK/NF-kappaB signaling (GO:0038061)4.72262185
18regulation of neuronal synaptic plasticity (GO:0048168)4.66035781
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.65445459
20regulation of long-term neuronal synaptic plasticity (GO:0048169)4.61861996
21exploration behavior (GO:0035640)4.60567785
22amyloid precursor protein catabolic process (GO:0042987)4.51346698
23protein localization to synapse (GO:0035418)4.47441164
24dendritic spine morphogenesis (GO:0060997)4.46416325
25regulation of synaptic vesicle exocytosis (GO:2000300)4.45192963
26synaptic vesicle exocytosis (GO:0016079)4.43784599
27negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.43336362
28negative regulation of DNA-templated transcription, elongation (GO:0032785)4.42211192
29peptidyl-arginine methylation (GO:0018216)4.41549331
30peptidyl-arginine N-methylation (GO:0035246)4.41549331
31deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.24434117
32protein insertion into membrane (GO:0051205)4.21113083
33histone arginine methylation (GO:0034969)4.18664171
34G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)4.02870433
35negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.97947377
36positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.95284092
37pentose metabolic process (GO:0019321)3.88365348
38regulation of synaptic vesicle transport (GO:1902803)3.88348936
39ribosomal small subunit biogenesis (GO:0042274)3.83463190
40positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.82624849
41proline transport (GO:0015824)3.81634934
42regulation of chromatin binding (GO:0035561)3.78265175
43activation of protein kinase A activity (GO:0034199)3.78185029
44positive regulation of synaptic transmission, GABAergic (GO:0032230)3.77589069
45positive regulation of histone deacetylation (GO:0031065)3.76734356
46neuromuscular process controlling balance (GO:0050885)3.76183251
47neurotransmitter secretion (GO:0007269)3.75869348
48ionotropic glutamate receptor signaling pathway (GO:0035235)3.74565234
49neurotransmitter-gated ion channel clustering (GO:0072578)3.73458721
50long-term memory (GO:0007616)3.71034265
51positive regulation of synapse maturation (GO:0090129)3.71029604
52regulation of dendritic spine morphogenesis (GO:0061001)3.69764910
53pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.69655995
54positive regulation of T cell apoptotic process (GO:0070234)3.68974410
55sodium ion export (GO:0071436)3.67678210
56regulation of ARF protein signal transduction (GO:0032012)3.62935420
57apoptotic process involved in morphogenesis (GO:0060561)3.59495462
58auditory behavior (GO:0031223)3.53434577
59positive regulation by symbiont of host defense response (GO:0052509)3.53062283
60modulation by symbiont of host defense response (GO:0052031)3.53062283
61modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.53062283
62modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.53062283
63positive regulation by organism of defense response of other organism involved in symbiotic interact3.53062283
64modulation by symbiont of host immune response (GO:0052553)3.53062283
65regulation of synaptic plasticity (GO:0048167)3.52609512
66clathrin coat assembly (GO:0048268)3.50685627
67positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.50258591
68motile cilium assembly (GO:0044458)3.49021056
69membrane protein intracellular domain proteolysis (GO:0031293)3.48829060
70regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 3.47038768
71protein retention in ER lumen (GO:0006621)3.45023688
72negative regulation of cell size (GO:0045792)3.43903026
73positive regulation of membrane potential (GO:0045838)3.42308188
74prepulse inhibition (GO:0060134)3.42162920
75amyloid precursor protein metabolic process (GO:0042982)3.38662209
76activation of Rac GTPase activity (GO:0032863)3.36823529
77synaptic transmission, glutamatergic (GO:0035249)3.36303554
78positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.35556684
79modulation by virus of host process (GO:0019054)3.34047552
80positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.32830380
81dendrite morphogenesis (GO:0048813)3.31399127
82tooth mineralization (GO:0034505)3.30938856
83intracellular estrogen receptor signaling pathway (GO:0030520)3.30347748
84neuron cell-cell adhesion (GO:0007158)3.28777472
85viral transcription (GO:0019083)3.26331201
86UTP biosynthetic process (GO:0006228)3.26213829
87cell migration in hindbrain (GO:0021535)3.26139581
88regulation of ARF GTPase activity (GO:0032312)3.25875380
89dopamine receptor signaling pathway (GO:0007212)3.25666713
90cellular potassium ion homeostasis (GO:0030007)3.24938124
91regulation of excitatory postsynaptic membrane potential (GO:0060079)3.24913017
92pyrimidine nucleotide catabolic process (GO:0006244)3.24900351
93guanosine-containing compound biosynthetic process (GO:1901070)3.22964220
94dendritic spine organization (GO:0097061)3.22690524
95proline biosynthetic process (GO:0006561)3.21229735
96iron-sulfur cluster assembly (GO:0016226)3.17938939
97metallo-sulfur cluster assembly (GO:0031163)3.17938939
98positive regulation of fibroblast migration (GO:0010763)3.17561058
99positive regulation of dendritic spine morphogenesis (GO:0061003)3.13366692
100regulation of fatty acid beta-oxidation (GO:0031998)3.12464453
101cell-cell junction maintenance (GO:0045217)3.12222159
102polyamine biosynthetic process (GO:0006596)3.09134377
103cerebellar Purkinje cell layer development (GO:0021680)3.08887745
104regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.08285986
105negative regulation of cell killing (GO:0031342)3.07899552
106negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.07899552
107positive regulation of lymphocyte apoptotic process (GO:0070230)3.07490346
108gamma-aminobutyric acid transport (GO:0015812)3.06966702
109response to auditory stimulus (GO:0010996)3.06604021
110GTP biosynthetic process (GO:0006183)3.06291933
111glutamate receptor signaling pathway (GO:0007215)3.02508198
112regulation of postsynaptic membrane potential (GO:0060078)3.01204959
113left/right pattern formation (GO:0060972)3.00409342
114cranial nerve morphogenesis (GO:0021602)2.97461577
115response to misfolded protein (GO:0051788)2.97158141
116axonemal dynein complex assembly (GO:0070286)2.96932837
117positive regulation of dendritic spine development (GO:0060999)2.96839905
118nucleosome disassembly (GO:0006337)2.95398588
119protein-DNA complex disassembly (GO:0032986)2.95398588
120neuron-neuron synaptic transmission (GO:0007270)2.95377693
121cytoskeletal anchoring at plasma membrane (GO:0007016)2.95270680
122UV protection (GO:0009650)2.94197673
123long-term synaptic potentiation (GO:0060291)2.93064535
124outflow tract septum morphogenesis (GO:0003148)2.92943506
125signal complex assembly (GO:0007172)2.92903746
126regulation of dendritic spine development (GO:0060998)2.92557377
127vesicle transport along microtubule (GO:0047496)2.91107148
128translational elongation (GO:0006414)2.90837288
129adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.88652706
130muscle cell fate commitment (GO:0042693)2.88463720
131membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.87629176
132translational termination (GO:0006415)2.87276414
133maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.86980311
134cellular response to virus (GO:0098586)2.86945152
135response to morphine (GO:0043278)2.86896045
136behavioral fear response (GO:0001662)2.86541180
137behavioral defense response (GO:0002209)2.86541180
138cell communication by electrical coupling (GO:0010644)2.86344716
139establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.85840288
140mitochondrion transport along microtubule (GO:0047497)2.85840288
141neuronal action potential propagation (GO:0019227)2.85527555
142dorsal/ventral neural tube patterning (GO:0021904)2.85453413
143neuron recognition (GO:0008038)2.84386116
144regulation of Rap GTPase activity (GO:0032317)2.84000198
145peptidyl-arginine modification (GO:0018195)2.83844187
146modulation by symbiont of host cellular process (GO:0044068)2.83456343
147regulation of neurotransmitter secretion (GO:0046928)2.83417921
148muscle organ morphogenesis (GO:0048644)2.83293263
149regulation of female receptivity (GO:0045924)2.82593836
150pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.82578928
151negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.81990636
152embryonic skeletal joint morphogenesis (GO:0060272)2.81865399
153UTP metabolic process (GO:0046051)2.80881248
154positive thymic T cell selection (GO:0045059)2.80488412
155positive regulation of Rap GTPase activity (GO:0032854)2.80478345
156regulation of apoptotic process involved in morphogenesis (GO:1902337)2.80272108
157neuronal ion channel clustering (GO:0045161)2.78917330
158retinoic acid receptor signaling pathway (GO:0048384)2.78300582
159response to isoquinoline alkaloid (GO:0014072)2.77887014
160negative regulation of cAMP-mediated signaling (GO:0043951)2.77784774
161cerebellar Purkinje cell differentiation (GO:0021702)2.77234887
162virion assembly (GO:0019068)2.77150240
163positive regulation of neurotransmitter secretion (GO:0001956)2.76336256
164nerve growth factor signaling pathway (GO:0038180)2.76256922
165glycine transport (GO:0015816)2.75949795
166learning (GO:0007612)2.73400155
167mitotic G1/S transition checkpoint (GO:0044819)2.73233265
168positive regulation of neurotransmitter transport (GO:0051590)2.73086981
169central nervous system projection neuron axonogenesis (GO:0021952)2.72887655
170regulation of synaptic transmission, glutamatergic (GO:0051966)2.72850057
171neuromuscular process (GO:0050905)2.72535446
172social behavior (GO:0035176)2.71767621
173intraspecies interaction between organisms (GO:0051703)2.71767621
174axonal fasciculation (GO:0007413)2.71280844
175establishment of nucleus localization (GO:0040023)2.70280419
176ncRNA 3-end processing (GO:0043628)2.69667383
177positive regulation of synaptic transmission (GO:0050806)2.68788340
178cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.68733855
179regulation of hydrogen peroxide metabolic process (GO:0010310)2.67121439
180neurotransmitter transport (GO:0006836)2.67009349
181regulation of interferon-gamma biosynthetic process (GO:0045072)2.66743841
182mitotic G1 DNA damage checkpoint (GO:0031571)2.66677347
183adenosine receptor signaling pathway (GO:0001973)2.66563926
184negative regulation of viral release from host cell (GO:1902187)2.66402092
185regulation of vesicle fusion (GO:0031338)2.65968790
186CTP biosynthetic process (GO:0006241)2.65949654
187CTP metabolic process (GO:0046036)2.65949654
188positive regulation of release of cytochrome c from mitochondria (GO:0090200)2.64720722
189rRNA transcription (GO:0009303)2.64396528
190positive regulation of protein deacetylation (GO:0090312)2.64296610
191regulation of synaptic transmission (GO:0050804)2.64264167
192establishment of mitochondrion localization (GO:0051654)2.63274368
193regulation of protein homodimerization activity (GO:0043496)2.62971638
194mitotic nuclear envelope reassembly (GO:0007084)2.61107857
195nuclear envelope reassembly (GO:0031468)2.61107857
196negative regulation of B cell apoptotic process (GO:0002903)2.60731290
197regulation of histone deacetylation (GO:0031063)2.60472421
198cell-substrate adherens junction assembly (GO:0007045)2.60233041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.85827112
2EZH2_22144423_ChIP-Seq_EOC_Human4.79346642
3* RARB_27405468_Chip-Seq_BRAIN_Mouse3.43522005
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.31776243
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.90001122
6TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.77469808
7REST_21632747_ChIP-Seq_MESCs_Mouse2.54100590
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.51250188
9* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.46818481
10DROSHA_22980978_ChIP-Seq_HELA_Human2.42869482
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.39534799
12* KDM2B_26808549_Chip-Seq_K562_Human2.34592578
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.34120456
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.33745496
15ZFP281_18757296_ChIP-ChIP_E14_Mouse2.31084113
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28874951
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28640462
18EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28640462
19TET1_21451524_ChIP-Seq_MESCs_Mouse2.22734959
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.19363602
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.18952372
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.18737962
23* KDM2B_26808549_Chip-Seq_DND41_Human2.17351901
24* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.15466268
25* EZH2_27294783_Chip-Seq_ESCs_Mouse2.13104308
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.08690395
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.08323777
28ZFP281_27345836_Chip-Seq_ESCs_Mouse1.99792197
29DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.99553557
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.99359233
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.98552118
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.97387429
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.91552137
34DNAJC2_21179169_ChIP-ChIP_NT2_Human1.89041222
35* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.87923380
36SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.86924882
37TP63_17297297_ChIP-ChIP_HaCaT_Human1.84772419
38NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.84197477
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.84123539
40STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82766520
41* KDM2B_26808549_Chip-Seq_JURKAT_Human1.81328259
42* MYC_22102868_ChIP-Seq_BL_Human1.80712417
43SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79828008
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.77369086
45SRY_22984422_ChIP-ChIP_TESTIS_Rat1.76434447
46EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.76368068
47CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.74512354
48* LXR_22292898_ChIP-Seq_THP-1_Human1.74231622
49ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.71933874
50* TCF7_22412390_ChIP-Seq_EML_Mouse1.70840630
51* ELF1_20517297_ChIP-Seq_JURKAT_Human1.70731070
52* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.69735658
53* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.67827884
54NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67608650
55* BCL6_27268052_Chip-Seq_Bcells_Human1.67222949
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.64064947
57MAF_26560356_Chip-Seq_TH2_Human1.63254619
58* XRN2_22483619_ChIP-Seq_HELA_Human1.62072211
59RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.59910323
60ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.57640623
61TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.56269146
62GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.56093204
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.54996910
64* BCOR_27268052_Chip-Seq_Bcells_Human1.53090377
65STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.53023319
66TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.49275628
67* MAF_26560356_Chip-Seq_TH1_Human1.47894002
68DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.46534764
69* RING1B_27294783_Chip-Seq_NPCs_Mouse1.44475575
70VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43553427
71SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.43378470
72SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.40896286
73ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40262390
74* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.39336816
75* FOXP1_21924763_ChIP-Seq_HESCs_Human1.38551258
76CTCF_21964334_Chip-Seq_Bcells_Human1.38247071
77EGR1_19374776_ChIP-ChIP_THP-1_Human1.37016998
78DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.35666964
79SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.35324596
80MYC_18358816_ChIP-ChIP_MESCs_Mouse1.34446748
81CTCF_18555785_ChIP-Seq_MESCs_Mouse1.31283401
82TP53_22127205_ChIP-Seq_IMR90_Human1.31112728
83UTX_26944678_Chip-Seq_JUKART_Human1.30949371
84ZNF263_19887448_ChIP-Seq_K562_Human1.29616455
85CTCF_26484167_Chip-Seq_Bcells_Mouse1.29553409
86EED_16625203_ChIP-ChIP_MESCs_Mouse1.29435908
87RARA_24833708_ChIP-Seq_LIVER_Mouse1.28797496
88WT1_25993318_ChIP-Seq_PODOCYTE_Human1.28517545
89SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.28448229
90* PHF8_20622854_ChIP-Seq_HELA_Human1.27632749
91AR_21572438_ChIP-Seq_LNCaP_Human1.27425015
92* E2F1_20622854_ChIP-Seq_HELA_Human1.26315191
93MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.25998895
94THAP11_20581084_ChIP-Seq_MESCs_Mouse1.24314378
95VDR_24763502_ChIP-Seq_THP-1_Human1.23710777
96CTCF_21964334_ChIP-Seq_BJAB-B_Human1.23629263
97CREB1_26743006_Chip-Seq_LNCaP_Human1.23517290
98RARB_24833708_ChIP-Seq_LIVER_Mouse1.23369978
99CTCF_27219007_Chip-Seq_Bcells_Human1.22753292
100NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22345905
101RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20532191
102JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.19730907
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19092136
104SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.18818955
105CIITA_25753668_ChIP-Seq_RAJI_Human1.17432223
106CTCF_20526341_ChIP-Seq_ESCs_Human1.15764207
107* NCOR1_26117541_ChIP-Seq_K562_Human1.15549246
108THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.15493534
109* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.15012903
110TET1_21490601_ChIP-Seq_MESCs_Mouse1.14396051
111ESR2_21235772_ChIP-Seq_MCF-7_Human1.14395954
112* SMC4_20622854_ChIP-Seq_HELA_Human1.13488750
113CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.13316076
114ATF3_27146783_Chip-Seq_COLON_Human1.12734032
115PU.1_20513432_ChIP-Seq_Bcells_Mouse1.12475743
116ETS1_21867929_ChIP-Seq_TH2_Mouse1.11299320
117* YY1_22570637_ChIP-Seq_MALME-3M_Human1.10606767
118KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10467600
119* ELK3_25401928_ChIP-Seq_HUVEC_Human1.09977663
120TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.09963045
121* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.09936540
122PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.08772900
123YY1_21170310_ChIP-Seq_MESCs_Mouse1.07778073
124SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07200108
125* TP63_22573176_ChIP-Seq_HFKS_Human1.07196392
126PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05297733
127MYC_18555785_ChIP-Seq_MESCs_Mouse1.04823033
128* GABP_19822575_ChIP-Seq_HepG2_Human1.04445116
129SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04206476
130OCT4_19829295_ChIP-Seq_ESCs_Human1.03602044
131EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.02830254
132SA1_27219007_Chip-Seq_Bcells_Human1.01996527
133GATA1_26923725_Chip-Seq_HPCs_Mouse1.00931077
134EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00883174
135FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00683797
136AR_19668381_ChIP-Seq_PC3_Human1.00289887
137P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00131606
138KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98526260
139RACK7_27058665_Chip-Seq_MCF-7_Human0.98370838
140KLF4_19829295_ChIP-Seq_ESCs_Human0.95919524
141* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95163898
142DPY_21335234_ChIP-Seq_ESCs_Mouse0.94132282
143* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.92785880
144OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.92701942
145GBX2_23144817_ChIP-Seq_PC3_Human0.90610170
146* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89716262
147CTCF_27219007_Chip-Seq_ERYTHROID_Human0.88281107
148* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.88087885
149TP53_20018659_ChIP-ChIP_R1E_Mouse0.85338845
150* SA1_27219007_Chip-Seq_ERYTHROID_Human0.85180722
151GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.84331497
152RUNX1_27514584_Chip-Seq_MCF-7_Human0.84205639
153MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.83896512
154* P68_20966046_ChIP-Seq_HELA_Human0.83641467
155* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.83488909
156SMAD3_21741376_ChIP-Seq_ESCs_Human0.82872090
157VDR_21846776_ChIP-Seq_THP-1_Human0.80745356
158SOX2_21211035_ChIP-Seq_LN229_Gbm0.80618013
159SMAD3_21741376_ChIP-Seq_HESCs_Human0.80002427
160WDR5_24793694_ChIP-Seq_LNCAP_Human0.80000029
161P53_22127205_ChIP-Seq_FIBROBLAST_Human0.79651499
162SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.78525306
163ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.77141631

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.78553075
2MP0003635_abnormal_synaptic_transmissio4.17613929
3MP0002822_catalepsy4.14953799
4MP0004270_analgesia3.60634638
5MP0002063_abnormal_learning/memory/cond3.53594975
6MP0002249_abnormal_larynx_morphology3.47912667
7MP0000678_abnormal_parathyroid_gland3.39496878
8MP0009745_abnormal_behavioral_response3.25065524
9MP0003880_abnormal_central_pattern3.08103496
10MP0005423_abnormal_somatic_nervous2.98271512
11MP0002064_seizures2.78800686
12MP0010030_abnormal_orbit_morphology2.63344985
13MP0004858_abnormal_nervous_system2.60334001
14MP0008961_abnormal_basal_metabolism2.58887003
15MP0002572_abnormal_emotion/affect_behav2.56976737
16MP0004185_abnormal_adipocyte_glucose2.45722308
17MP0001968_abnormal_touch/_nociception2.42927139
18MP0004811_abnormal_neuron_physiology2.14495717
19MP0002734_abnormal_mechanical_nocicepti2.13560683
20MP0001486_abnormal_startle_reflex2.09633377
21MP0008260_abnormal_autophagy2.09360228
22MP0003303_peritoneal_inflammation2.08348940
23MP0003329_amyloid_beta_deposits2.04184901
24MP0005451_abnormal_body_composition2.01239038
25MP0002138_abnormal_hepatobiliary_system1.99528208
26MP0001873_stomach_inflammation1.98063318
27MP0001501_abnormal_sleep_pattern1.95647086
28MP0009780_abnormal_chondrocyte_physiolo1.90833619
29MP0002733_abnormal_thermal_nociception1.90603549
30MP0000537_abnormal_urethra_morphology1.89691932
31MP0002909_abnormal_adrenal_gland1.89395786
32MP0009046_muscle_twitch1.86051014
33MP0002272_abnormal_nervous_system1.85290865
34MP0004510_myositis1.81077128
35MP0001970_abnormal_pain_threshold1.79150566
36MP0000049_abnormal_middle_ear1.77867661
37MP0005501_abnormal_skin_physiology1.76869656
38MP0008569_lethality_at_weaning1.74864684
39MP0002735_abnormal_chemical_nociception1.67158738
40MP0002557_abnormal_social/conspecific_i1.67053018
41MP0001440_abnormal_grooming_behavior1.66767197
42MP0000778_abnormal_nervous_system1.65643999
43MP0003075_altered_response_to1.61901149
44MP0000955_abnormal_spinal_cord1.59191535
45MP0009053_abnormal_anal_canal1.58363601
46MP0002184_abnormal_innervation1.53381452
47MP0009333_abnormal_splenocyte_physiolog1.48042639
48MP0003787_abnormal_imprinting1.46932135
49MP0004885_abnormal_endolymph1.46397637
50MP0003879_abnormal_hair_cell1.46060895
51MP0005083_abnormal_biliary_tract1.45017818
52MP0002736_abnormal_nociception_after1.43524260
53MP0010234_abnormal_vibrissa_follicle1.40241534
54MP0004924_abnormal_behavior1.39485775
55MP0005386_behavior/neurological_phenoty1.39485775
56MP0001348_abnormal_lacrimal_gland1.39266367
57MP0000750_abnormal_muscle_regeneration1.34125383
58MP0005623_abnormal_meninges_morphology1.31610082
59MP0000733_abnormal_muscle_development1.30689227
60MP0001502_abnormal_circadian_rhythm1.28526801
61MP0002882_abnormal_neuron_morphology1.27540821
62MP0001984_abnormal_olfaction1.27039236
63MP0002066_abnormal_motor_capabilities/c1.23304651
64MP0005076_abnormal_cell_differentiation1.22947701
65MP0000681_abnormal_thyroid_gland1.22218916
66MP0002067_abnormal_sensory_capabilities1.20110774
67MP0002152_abnormal_brain_morphology1.19570915
68MP0003453_abnormal_keratinocyte_physiol1.19541393
69MP0003633_abnormal_nervous_system1.19343324
70MP0003283_abnormal_digestive_organ1.18939021
71MP0005666_abnormal_adipose_tissue1.18173555
72MP0005058_abnormal_lysosome_morphology1.18004035
73MP0002932_abnormal_joint_morphology1.16337771
74MP0005310_abnormal_salivary_gland1.15721597
75MP0003942_abnormal_urinary_system1.14377367
76MP0002877_abnormal_melanocyte_morpholog1.12509706
77MP0002796_impaired_skin_barrier1.11038093
78MP0004381_abnormal_hair_follicle1.09321305
79MP0001661_extended_life_span1.08501683
80MP0002653_abnormal_ependyma_morphology1.05133624
81MP0003436_decreased_susceptibility_to1.03441741
82MP0003763_abnormal_thymus_physiology1.02452910
83MP0005375_adipose_tissue_phenotype0.98521822
84MP0008874_decreased_physiological_sensi0.98453762
85MP0000604_amyloidosis0.97831565
86MP0004133_heterotaxia0.96932762
87MP0004947_skin_inflammation0.96246843
88MP0009278_abnormal_bone_marrow0.95994654
89MP0000703_abnormal_thymus_morphology0.95040310
90MP0000569_abnormal_digit_pigmentation0.92103826
91MP0002398_abnormal_bone_marrow0.90990700
92MP0003631_nervous_system_phenotype0.90052344
93MP0001800_abnormal_humoral_immune0.89790707
94MP0001919_abnormal_reproductive_system0.89753712
95MP0005499_abnormal_olfactory_system0.89680244
96MP0005394_taste/olfaction_phenotype0.89680244
97MP0008932_abnormal_embryonic_tissue0.89290210
98MP0005464_abnormal_platelet_physiology0.88572767
99MP0001346_abnormal_lacrimal_gland0.87465934
100MP0002928_abnormal_bile_duct0.86890322
101MP0002069_abnormal_eating/drinking_beha0.85499695
102MP0002089_abnormal_postnatal_growth/wei0.85432157
103MP0001727_abnormal_embryo_implantation0.85282320
104MP0003861_abnormal_nervous_system0.84711512
105MP0003122_maternal_imprinting0.84201415
106MP0000013_abnormal_adipose_tissue0.84029625
107MP0000313_abnormal_cell_death0.83764233
108MP0001188_hyperpigmentation0.82487294
109MP0002132_abnormal_respiratory_system0.81918025
110MP0001905_abnormal_dopamine_level0.81716585
111MP0005167_abnormal_blood-brain_barrier0.81082386
112MP0002723_abnormal_immune_serum0.78655576
113MP0003705_abnormal_hypodermis_morpholog0.77464687
114MP0003634_abnormal_glial_cell0.76777789
115MP0009384_cardiac_valve_regurgitation0.75938673
116MP0000613_abnormal_salivary_gland0.74733861
117MP0002429_abnormal_blood_cell0.74410726
118MP0003191_abnormal_cellular_cholesterol0.74282197
119MP0003077_abnormal_cell_cycle0.73789873
120MP0000858_altered_metastatic_potential0.73516888
121MP0003300_gastrointestinal_ulcer0.73454121
122MP0003698_abnormal_male_reproductive0.73445793
123MP0008770_decreased_survivor_rate0.72368137
124MP0003693_abnormal_embryo_hatching0.71652998
125MP0000026_abnormal_inner_ear0.71546033
126MP0001819_abnormal_immune_cell0.70678402
127MP0002420_abnormal_adaptive_immunity0.70458923
128MP0008872_abnormal_physiological_respon0.70004754
129MP0000015_abnormal_ear_pigmentation0.69529979
130MP0003172_abnormal_lysosome_physiology0.69426395
131MP0009931_abnormal_skin_appearance0.69242717
132MP0001340_abnormal_eyelid_morphology0.68287643
133MP0003091_abnormal_cell_migration0.67679936
134MP0003123_paternal_imprinting0.67668135
135MP0000716_abnormal_immune_system0.67567814
136MP0003119_abnormal_digestive_system0.67395307
137MP0005409_darkened_coat_color0.67328800
138MP0005387_immune_system_phenotype0.67187247
139MP0001790_abnormal_immune_system0.67187247
140MP0002116_abnormal_craniofacial_bone0.66638507
141MP0005410_abnormal_fertilization0.66397003
142MP0002722_abnormal_immune_system0.66250975
143MP0000538_abnormal_urinary_bladder0.65785779
144MP0005621_abnormal_cell_physiology0.65249971
145MP0005166_decreased_susceptibility_to0.64018008
146MP0000470_abnormal_stomach_morphology0.63625423
147MP0000689_abnormal_spleen_morphology0.63097781
148MP0001177_atelectasis0.63056313
149MP0002234_abnormal_pharynx_morphology0.62622775
150MP0001849_ear_inflammation0.62597172
151MP0005645_abnormal_hypothalamus_physiol0.62522788
152MP0005646_abnormal_pituitary_gland0.61628421
153MP0000751_myopathy0.57522967
154MP0010769_abnormal_survival0.56705704
155MP0001529_abnormal_vocalization0.55908499
156MP0004233_abnormal_muscle_weight0.54868891
157MP0004085_abnormal_heartbeat0.54666283
158MP0004142_abnormal_muscle_tone0.53206494
159MP0010768_mortality/aging0.53093137
160MP0003956_abnormal_body_size0.50698363
161MP0002081_perinatal_lethality0.50626598
162MP0010352_gastrointestinal_tract_polyps0.50453618
163MP0000631_abnormal_neuroendocrine_gland0.49926047
164MP0001943_abnormal_respiration0.49176266
165MP0002082_postnatal_lethality0.49007342
166MP0010770_preweaning_lethality0.49007342
167MP0005535_abnormal_body_temperature0.48454081
168MP0000534_abnormal_ureter_morphology0.47808922
169MP0003632_abnormal_nervous_system0.47198393
170MP0000003_abnormal_adipose_tissue0.47102813

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.50146036
2Focal motor seizures (HP:0011153)4.53625874
3Visual hallucinations (HP:0002367)4.16568186
4Focal seizures (HP:0007359)4.06829484
5Abnormality of the lower motor neuron (HP:0002366)4.04963464
6Double outlet right ventricle (HP:0001719)3.83443604
7Congenital malformation of the right heart (HP:0011723)3.83443604
8Hyperthyroidism (HP:0000836)3.78777843
9Papilledema (HP:0001085)3.62711974
10Broad distal phalanx of finger (HP:0009836)3.62314332
11Abnormality of the aortic arch (HP:0012303)3.57697156
12Annular pancreas (HP:0001734)3.46434554
13Mutism (HP:0002300)3.45171707
14Agammaglobulinemia (HP:0004432)3.32760125
15Supranuclear gaze palsy (HP:0000605)3.28001158
16Nasal polyposis (HP:0100582)3.24475129
17Amyotrophic lateral sclerosis (HP:0007354)3.21446583
18Testicular atrophy (HP:0000029)3.18826198
19Stridor (HP:0010307)3.17900738
20Ankle clonus (HP:0011448)3.13333476
21Pointed chin (HP:0000307)3.03485663
22Impaired vibration sensation in the lower limbs (HP:0002166)3.01505632
23Depression (HP:0000716)2.99314770
24Obstructive sleep apnea (HP:0002870)2.92772966
25Action tremor (HP:0002345)2.92136816
26Atelectasis (HP:0100750)2.89225343
27Megalencephaly (HP:0001355)2.89130152
28Epileptic encephalopathy (HP:0200134)2.88489556
29Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.84863201
30Insomnia (HP:0100785)2.82785315
31Cellulitis (HP:0100658)2.80303174
32Urinary urgency (HP:0000012)2.78086444
33Poor eye contact (HP:0000817)2.77629113
34Atonic seizures (HP:0010819)2.76262100
35Long palpebral fissure (HP:0000637)2.70379808
36Hypertensive crisis (HP:0100735)2.70308302
37Ulnar bowing (HP:0003031)2.67547393
38Torticollis (HP:0000473)2.67424934
39Aplasia/Hypoplasia of the sacrum (HP:0008517)2.66544654
40Urinary bladder sphincter dysfunction (HP:0002839)2.65601226
41Thin bony cortex (HP:0002753)2.64086197
42Hyperacusis (HP:0010780)2.63550905
43Ankyloglossia (HP:0010296)2.61573116
44Impaired social interactions (HP:0000735)2.60025696
45Abnormal social behavior (HP:0012433)2.60025696
46Apathy (HP:0000741)2.58963687
47Amblyopia (HP:0000646)2.58422050
48Febrile seizures (HP:0002373)2.57591958
49Genetic anticipation (HP:0003743)2.57355783
50Stereotypic behavior (HP:0000733)2.55173771
51Hemiplegia (HP:0002301)2.54051811
52Achilles tendon contracture (HP:0001771)2.50446404
53Absence seizures (HP:0002121)2.50290231
54Progressive cerebellar ataxia (HP:0002073)2.49952867
55Abnormal eating behavior (HP:0100738)2.49729438
56Unilateral renal agenesis (HP:0000122)2.49681325
57Gastrointestinal stroma tumor (HP:0100723)2.47874609
58Recurrent otitis media (HP:0000403)2.45042979
59Increased density of long bones (HP:0006392)2.42109610
60Seborrheic dermatitis (HP:0001051)2.35131772
61Bulbar palsy (HP:0001283)2.34617394
62Diminished motivation (HP:0000745)2.34531250
63Postural instability (HP:0002172)2.33901571
64Cerebral inclusion bodies (HP:0100314)2.33691174
65Peripheral hypomyelination (HP:0007182)2.33381291
66Focal dystonia (HP:0004373)2.33065093
67Male infertility (HP:0003251)2.32819360
68Abnormality of oral frenula (HP:0000190)2.30735030
69Abnormality of the nasal mucosa (HP:0000433)2.29749080
70Down-sloping shoulders (HP:0200021)2.29694243
71Generalized tonic-clonic seizures (HP:0002069)2.29441411
72Dialeptic seizures (HP:0011146)2.29430076
73Dynein arm defect of respiratory motile cilia (HP:0012255)2.27543655
74Absent/shortened dynein arms (HP:0200106)2.27543655
75Diplopia (HP:0000651)2.26953753
76Abnormality of binocular vision (HP:0011514)2.26953753
77Prolonged neonatal jaundice (HP:0006579)2.26412476
78Hypoparathyroidism (HP:0000829)2.25305380
79Akinesia (HP:0002304)2.25304006
80Dysmetria (HP:0001310)2.25136594
81Micronodular cirrhosis (HP:0001413)2.24710339
82Abnormality of the distal phalanges of the toes (HP:0010182)2.24121642
83Spastic gait (HP:0002064)2.23933497
84Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.22084056
85Increased intramyocellular lipid droplets (HP:0012240)2.22004309
86Severe visual impairment (HP:0001141)2.20734474
87Upper limb amyotrophy (HP:0009129)2.20355681
88Distal upper limb amyotrophy (HP:0007149)2.20355681
89Lower limb amyotrophy (HP:0007210)2.20298865
90Increased muscle lipid content (HP:0009058)2.18793106
91Impaired smooth pursuit (HP:0007772)2.18469149
92Turricephaly (HP:0000262)2.18023260
93Broad face (HP:0000283)2.17589801
94Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.17066733
95Distal lower limb muscle weakness (HP:0009053)2.16772542
96Recurrent bacterial skin infections (HP:0005406)2.16075011
97Microretrognathia (HP:0000308)2.15246865
98Abnormality of the Achilles tendon (HP:0005109)2.14782589
99Abnormal respiratory motile cilium physiology (HP:0012261)2.14501106
100Insidious onset (HP:0003587)2.13653109
101Termporal pattern (HP:0011008)2.13653109
102Dysdiadochokinesis (HP:0002075)2.12394874
103Broad-based gait (HP:0002136)2.11371910
104Truncal ataxia (HP:0002078)2.10419212
105Craniofacial dystonia (HP:0012179)2.08119050
106Anxiety (HP:0000739)2.07901444
107Bundle branch block (HP:0011710)2.07182609
108Neurofibrillary tangles (HP:0002185)2.04901313
109Abnormality of ocular smooth pursuit (HP:0000617)2.01341157
110Ventricular fibrillation (HP:0001663)2.01243153
111Abnormal ventriculo-arterial connection (HP:0011563)2.01090229
112Transposition of the great arteries (HP:0001669)2.01090229
113Abnormal connection of the cardiac segments (HP:0011545)2.01090229
114Bradykinesia (HP:0002067)2.00867301
115Patellar dislocation (HP:0002999)2.00807109
116High anterior hairline (HP:0009890)1.99490804
117Generalized hypotonia (HP:0001290)1.99249689
118Abnormal respiratory motile cilium morphology (HP:0005938)1.98941789
119Abnormal respiratory epithelium morphology (HP:0012253)1.98941789
120Self-mutilation (HP:0000742)1.98806393
121Hypercortisolism (HP:0001578)1.98636691
122Distal lower limb amyotrophy (HP:0008944)1.98395139
123Resting tremor (HP:0002322)1.98281206
124Deep palmar crease (HP:0006191)1.97231334
125Hypergonadotropic hypogonadism (HP:0000815)1.96832193
126Inappropriate behavior (HP:0000719)1.95764094
127Dysmetric saccades (HP:0000641)1.93848864
128Ragged-red muscle fibers (HP:0003200)1.93838792
129Easy fatigability (HP:0003388)1.93029794
130Hemiparesis (HP:0001269)1.91968160
131Genu recurvatum (HP:0002816)1.91471528
132Intention tremor (HP:0002080)1.90994415
133Intellectual disability, profound (HP:0002187)1.89776582
134Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.89585384
135Hemorrhage of the eye (HP:0011885)1.89221121
136Obstructive lung disease (HP:0006536)1.88690657
137Chronic obstructive pulmonary disease (HP:0006510)1.88690657
138Abnormality of the radial head (HP:0003995)1.86783809
139Periauricular skin pits (HP:0100277)1.86099605
140Preauricular pit (HP:0004467)1.86099605
141Neuronal loss in central nervous system (HP:0002529)1.86064399
142Cerebral aneurysm (HP:0004944)1.86005955
143Colitis (HP:0002583)1.85622400
144Bowing of the arm (HP:0006488)1.85238727
145Bowed forearm bones (HP:0003956)1.85238727
146Abnormality of the corticospinal tract (HP:0002492)1.84812688
147Macroorchidism (HP:0000053)1.84648056
148Neoplasm of the heart (HP:0100544)1.84078008
149Rapidly progressive (HP:0003678)1.84058472
150Dislocated radial head (HP:0003083)1.83422296
151Lower limb muscle weakness (HP:0007340)1.82981761
152Abnormal ciliary motility (HP:0012262)1.82950621
153Lower limb asymmetry (HP:0100559)1.82646043
154Gaze-evoked nystagmus (HP:0000640)1.82279812
155Papilloma (HP:0012740)1.81804298
156Verrucae (HP:0200043)1.81804298
157Breast hypoplasia (HP:0003187)1.81745604
158Drooling (HP:0002307)1.81325165
159Excessive salivation (HP:0003781)1.81325165
160Shallow orbits (HP:0000586)1.80978519
161Hand muscle atrophy (HP:0009130)1.80810254
162Reticulocytosis (HP:0001923)1.80683049
163Bowel incontinence (HP:0002607)1.80662053
164Elfin facies (HP:0004428)1.80102999
165Limb dystonia (HP:0002451)1.79834976
166Disproportionate tall stature (HP:0001519)1.79361018
167Growth hormone excess (HP:0000845)1.79068826
168Short femoral neck (HP:0100864)1.78794650
169Flattened epiphyses (HP:0003071)1.77809072
170Spinal canal stenosis (HP:0003416)1.77009165
171Overriding aorta (HP:0002623)1.76882974
172Renal duplication (HP:0000075)1.75437737
173Failure to thrive in infancy (HP:0001531)1.74658121
174Bronchomalacia (HP:0002780)1.71731843
175Impaired vibratory sensation (HP:0002495)1.71517258
176Cholelithiasis (HP:0001081)1.70892301
177Aqueductal stenosis (HP:0002410)1.70594361
178Recurrent sinusitis (HP:0011108)1.70416380
179Abnormal large intestine physiology (HP:0012700)1.70265153
180Viral hepatitis (HP:0006562)1.67983062
181Infertility (HP:0000789)1.67977562
182Truncus arteriosus (HP:0001660)1.67815208

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.75922519
2SMG14.12655263
3EPHA44.00309043
4IRAK33.59810408
5MARK13.49981240
6NTRK33.23974854
7PRKD33.21258534
8SIK13.19166233
9NME22.97983040
10KSR22.72871397
11DAPK22.45676443
12MAP3K112.44203553
13PAK62.39551652
14MINK12.27842850
15EPHA22.16079266
16TAOK12.15133770
17VRK22.12809341
18ERN12.09058501
19TYRO32.09042599
20CAMKK12.05706403
21SIK22.01610379
22TRIB31.99821299
23NTRK21.99346141
24IRAK41.95199233
25TESK21.85325124
26IRAK21.84228344
27MAP3K41.83048743
28ALK1.81508040
29KSR11.78428803
30PIM21.66059144
31NTRK11.58542411
32LATS21.56684217
33MAP3K131.50816512
34CDK51.50282726
35EEF2K1.47349972
36MAP3K21.43215107
37MARK21.40258247
38DAPK11.35308750
39MAPK151.32690400
40ARAF1.30897206
41ICK1.30430194
42BRAF1.26697275
43RIPK11.25270992
44STK111.24555379
45STK381.24319650
46FES1.23912126
47STK161.21662659
48UHMK11.17986441
49PRKCH1.17637673
50PKN21.13775554
51TAOK21.12712904
52MUSK1.09600244
53RET1.07706589
54RPS6KB21.05164565
55PRKCI1.04704562
56RAF11.02991744
57SIK31.02978406
58MAP3K101.02272828
59PRPF4B1.00508859
60MAP2K21.00316774
61DYRK1B0.97050821
62AURKA0.96888438
63GRK50.96082255
64CDK150.95831214
65TAF10.95406888
66MAPK110.94964430
67BMX0.94258185
68SCYL20.93953969
69ILK0.93508692
70TBK10.92594963
71CDK180.92397890
72BCKDK0.91307365
73DMPK0.90457253
74CDK140.90033996
75MAP2K40.88270288
76CDK11A0.87378102
77MAP2K70.87163774
78GRK60.83741441
79PHKG20.82076756
80PHKG10.82076756
81DYRK30.81674831
82CDK70.80860739
83RIPK40.80373453
84PDK10.79048775
85BLK0.78897529
86MAP3K80.77023586
87PRKCG0.76438160
88MTOR0.76129925
89MAP2K30.75339210
90EPHB20.73651595
91MAP3K70.72103703
92MAP3K10.70019354
93TESK10.68946630
94IKBKE0.66194132
95PTK2B0.65429730
96RPS6KC10.65144155
97RPS6KL10.65144155
98RPS6KA20.64227268
99IRAK10.63284754
100LRRK20.61457231
101NEK10.61348080
102CAMK10.61126695
103PDPK10.60509593
104MAPK130.59179702
105MAPK120.58900998
106KDR0.58801716
107TNK20.58792163
108MAP2K10.58009091
109LMTK20.56749243
110CDK120.56338980
111BRSK10.56228441
112PAK30.56032573
113TLK10.54472632
114PRKCZ0.54356117
115CAMK1D0.52915545
116MST1R0.52192267
117CHUK0.51733390
118RPS6KA60.50855168
119HCK0.50818887
120DYRK1A0.50549473
121MAP4K10.50321784
122PRKD20.50032132
123DAPK30.49568825
124IKBKB0.49556573
125PDGFRA0.49528995
126MAP3K30.49496206
127DDR20.49448222
128CSNK1G20.49357877
129PLK20.48448807
130SGK30.48401795
131CAMK40.47365718
132FYN0.46102948
133ABL20.45862584
134RPS6KA10.45010671
135CDK80.44147205
136MAPKAPK30.43589824
137CAMK2A0.42455382
138RPS6KA30.42154406
139SGK10.42030340
140MOS0.40549442
141PAK10.39559715
142PAK40.38347356
143CDK90.38075420
144MAPK80.37801129
145ZAP700.37221465
146MAPKAPK20.37007780
147CSNK1G30.36890494
148MAPK100.36227633
149BUB10.35607756
150CDC42BPA0.33766157
151CHEK20.33718142
152MAP2K60.33073322
153PDGFRB0.32364367
154PTK20.31834794
155LIMK10.31757197
156CDK190.31473693
157AKT20.30889949
158BTK0.30485222
159TNIK0.29286553
160FGFR30.28096928
161MAPK90.27481509
162JAK10.26838552
163MAP3K60.25766711
164PTK60.25019120
165HIPK20.24806949

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041225.44013952
2Olfactory transduction_Homo sapiens_hsa047402.69452476
3Notch signaling pathway_Homo sapiens_hsa043302.69353336
4Ribosome_Homo sapiens_hsa030102.46767357
5Synaptic vesicle cycle_Homo sapiens_hsa047212.39430519
6Long-term potentiation_Homo sapiens_hsa047202.33731816
7Circadian entrainment_Homo sapiens_hsa047132.11227922
8Amphetamine addiction_Homo sapiens_hsa050312.05392890
9Nicotine addiction_Homo sapiens_hsa050332.05058268
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.03102995
11Morphine addiction_Homo sapiens_hsa050321.90895573
12Glutamatergic synapse_Homo sapiens_hsa047241.90851210
13GABAergic synapse_Homo sapiens_hsa047271.88004274
14Dopaminergic synapse_Homo sapiens_hsa047281.85240526
15Cholinergic synapse_Homo sapiens_hsa047251.77383775
16Cocaine addiction_Homo sapiens_hsa050301.72085891
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71258790
18Fructose and mannose metabolism_Homo sapiens_hsa000511.69637540
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66460882
20Salivary secretion_Homo sapiens_hsa049701.62511038
21Base excision repair_Homo sapiens_hsa034101.59737145
22Gastric acid secretion_Homo sapiens_hsa049711.59000788
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58604447
24Oxytocin signaling pathway_Homo sapiens_hsa049211.53354737
25Insulin secretion_Homo sapiens_hsa049111.51059056
26Glioma_Homo sapiens_hsa052141.51048894
27GnRH signaling pathway_Homo sapiens_hsa049121.45908155
28Estrogen signaling pathway_Homo sapiens_hsa049151.43952488
29Renin secretion_Homo sapiens_hsa049241.35258205
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.34896934
31Gap junction_Homo sapiens_hsa045401.33910807
32Primary immunodeficiency_Homo sapiens_hsa053401.30581268
33Neurotrophin signaling pathway_Homo sapiens_hsa047221.30384939
34Type II diabetes mellitus_Homo sapiens_hsa049301.26842478
35Pyrimidine metabolism_Homo sapiens_hsa002401.26152343
36VEGF signaling pathway_Homo sapiens_hsa043701.25972460
37Basal cell carcinoma_Homo sapiens_hsa052171.25130700
38Long-term depression_Homo sapiens_hsa047301.24604789
39Galactose metabolism_Homo sapiens_hsa000521.24204829
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24012535
41ErbB signaling pathway_Homo sapiens_hsa040121.22881473
42Biosynthesis of amino acids_Homo sapiens_hsa012301.22379447
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.19380828
44Axon guidance_Homo sapiens_hsa043601.18378499
45mTOR signaling pathway_Homo sapiens_hsa041501.16580310
46cAMP signaling pathway_Homo sapiens_hsa040241.16568997
47Dorso-ventral axis formation_Homo sapiens_hsa043201.14319186
48Pentose phosphate pathway_Homo sapiens_hsa000301.14209834
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13104584
50Calcium signaling pathway_Homo sapiens_hsa040201.12108300
51Melanogenesis_Homo sapiens_hsa049161.12103644
52Toll-like receptor signaling pathway_Homo sapiens_hsa046201.11477474
53Other glycan degradation_Homo sapiens_hsa005111.09889185
54Non-small cell lung cancer_Homo sapiens_hsa052231.07536056
55Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06925959
56Endometrial cancer_Homo sapiens_hsa052131.06051125
57Phospholipase D signaling pathway_Homo sapiens_hsa040721.03716258
58MAPK signaling pathway_Homo sapiens_hsa040101.03458188
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.02545523
60Oocyte meiosis_Homo sapiens_hsa041141.00892996
61Apoptosis_Homo sapiens_hsa042101.00557798
62cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00491915
63N-Glycan biosynthesis_Homo sapiens_hsa005101.00314880
64HTLV-I infection_Homo sapiens_hsa051660.99947151
65Serotonergic synapse_Homo sapiens_hsa047260.98504847
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.95438859
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95429186
68T cell receptor signaling pathway_Homo sapiens_hsa046600.95346461
69Hepatitis C_Homo sapiens_hsa051600.95183914
70AMPK signaling pathway_Homo sapiens_hsa041520.93691213
71Colorectal cancer_Homo sapiens_hsa052100.92301684
72Renal cell carcinoma_Homo sapiens_hsa052110.91811934
73Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.90888769
74Hepatitis B_Homo sapiens_hsa051610.90798653
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.90405944
76Viral carcinogenesis_Homo sapiens_hsa052030.89850748
77Endocytosis_Homo sapiens_hsa041440.89426438
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.87881972
79Chronic myeloid leukemia_Homo sapiens_hsa052200.87128761
80Taste transduction_Homo sapiens_hsa047420.86973431
81Choline metabolism in cancer_Homo sapiens_hsa052310.84967252
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.84641174
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.84221867
84Prolactin signaling pathway_Homo sapiens_hsa049170.83782189
85Rap1 signaling pathway_Homo sapiens_hsa040150.83552422
86Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.83283999
87Chemokine signaling pathway_Homo sapiens_hsa040620.82345539
88Hedgehog signaling pathway_Homo sapiens_hsa043400.82125064
89Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80729040
90B cell receptor signaling pathway_Homo sapiens_hsa046620.80661784
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.80516310
92Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79820762
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79790904
94Inositol phosphate metabolism_Homo sapiens_hsa005620.78137161
95Melanoma_Homo sapiens_hsa052180.77743496
96Vascular smooth muscle contraction_Homo sapiens_hsa042700.77247771
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75921880
98Epstein-Barr virus infection_Homo sapiens_hsa051690.75836671
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.75253075
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.72492487
101Osteoclast differentiation_Homo sapiens_hsa043800.71944951
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.70835814
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70317897
104Insulin signaling pathway_Homo sapiens_hsa049100.69064123
105Systemic lupus erythematosus_Homo sapiens_hsa053220.68472819
106Shigellosis_Homo sapiens_hsa051310.67483834
107Ras signaling pathway_Homo sapiens_hsa040140.67386410
108Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.66164504
109Glucagon signaling pathway_Homo sapiens_hsa049220.65783708
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.64759558
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.64732713
112Acute myeloid leukemia_Homo sapiens_hsa052210.64723434
113Central carbon metabolism in cancer_Homo sapiens_hsa052300.64592214
114Alcoholism_Homo sapiens_hsa050340.63121225
115Herpes simplex infection_Homo sapiens_hsa051680.62057826
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61402692
117Wnt signaling pathway_Homo sapiens_hsa043100.61131068
118Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.60852028
119Vibrio cholerae infection_Homo sapiens_hsa051100.60844052
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60822412
121Pancreatic cancer_Homo sapiens_hsa052120.59939644
122Dilated cardiomyopathy_Homo sapiens_hsa054140.59535859
123Thyroid hormone synthesis_Homo sapiens_hsa049180.58589092
124Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.58325576
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56968718
126Platelet activation_Homo sapiens_hsa046110.56731024
127Prion diseases_Homo sapiens_hsa050200.56314616
128Circadian rhythm_Homo sapiens_hsa047100.55985584
129Insulin resistance_Homo sapiens_hsa049310.54854991
130Thyroid cancer_Homo sapiens_hsa052160.54760817
131Phenylalanine metabolism_Homo sapiens_hsa003600.53483974
132TNF signaling pathway_Homo sapiens_hsa046680.53259510
133Glycerophospholipid metabolism_Homo sapiens_hsa005640.51830254
134Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51235299
135Bladder cancer_Homo sapiens_hsa052190.50646674
136Small cell lung cancer_Homo sapiens_hsa052220.50188676
137Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49733172
138Hippo signaling pathway_Homo sapiens_hsa043900.49450866
139Salmonella infection_Homo sapiens_hsa051320.49135560
140FoxO signaling pathway_Homo sapiens_hsa040680.48165556
141Nitrogen metabolism_Homo sapiens_hsa009100.48014025
142Proteoglycans in cancer_Homo sapiens_hsa052050.47905268
143Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.47203158
144DNA replication_Homo sapiens_hsa030300.47168306
145Prostate cancer_Homo sapiens_hsa052150.46266504
146Fatty acid biosynthesis_Homo sapiens_hsa000610.45389426
147Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42973318
148Influenza A_Homo sapiens_hsa051640.42672250
149Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40862354

Most similar genes based on co-expression Upload to Enrichr

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