PRR9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1citrulline biosynthetic process (GO:0019240)8.85652927
2adhesion of symbiont to host (GO:0044406)8.62662278
3peptide cross-linking (GO:0018149)8.55046606
4hair follicle morphogenesis (GO:0031069)8.06331638
5intermediate filament cytoskeleton organization (GO:0045104)6.80499232
6intermediate filament-based process (GO:0045103)6.58626714
7cell wall macromolecule metabolic process (GO:0044036)6.41216311
8cell wall macromolecule catabolic process (GO:0016998)6.41216311
9linoleic acid metabolic process (GO:0043651)6.25245628
10epidermis development (GO:0008544)6.20676375
11establishment of skin barrier (GO:0061436)6.11271768
12keratinocyte differentiation (GO:0030216)6.05947123
13citrulline metabolic process (GO:0000052)5.85019220
14bundle of His cell to Purkinje myocyte communication (GO:0086069)5.52152913
15regulation of water loss via skin (GO:0033561)5.43145010
16hair cycle process (GO:0022405)5.32857256
17molting cycle process (GO:0022404)5.32857256
18hemidesmosome assembly (GO:0031581)5.24545765
19skin morphogenesis (GO:0043589)5.15536954
20peptidyl-arginine modification (GO:0018195)4.88758635
21epidermal cell differentiation (GO:0009913)4.73729966
22regulation of transforming growth factor beta1 production (GO:0032908)4.65303344
23long-chain fatty acid biosynthetic process (GO:0042759)4.63590049
24regulation of cell proliferation involved in kidney development (GO:1901722)4.30405422
25lipoxygenase pathway (GO:0019372)4.06611498
26hair cycle (GO:0042633)33.7116222
27molting cycle (GO:0042303)33.7116222
28regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.92350971
29keratinocyte development (GO:0003334)3.91832540
30tooth mineralization (GO:0034505)3.91094189
31long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.79253151
32defense response to fungus (GO:0050832)3.75829093
33multicellular organismal water homeostasis (GO:0050891)3.67582802
34fatty-acyl-CoA biosynthetic process (GO:0046949)3.58568498
35positive regulation of cellular amide metabolic process (GO:0034250)3.56594036
36polarized epithelial cell differentiation (GO:0030859)3.54028427
37negative regulation of keratinocyte proliferation (GO:0010839)3.45355853
38detection of bacterium (GO:0016045)3.42163656
39endocardial cushion development (GO:0003197)3.40598226
40regulation of glomerulus development (GO:0090192)3.40374230
41retinol metabolic process (GO:0042572)3.31070459
42negative regulation of establishment of protein localization to plasma membrane (GO:0090005)3.30018184
43hair follicle development (GO:0001942)3.29611161
44positive regulation of keratinocyte differentiation (GO:0045618)3.27292931
45negative regulation of stem cell proliferation (GO:2000647)3.23635999
46regulation of keratinocyte differentiation (GO:0045616)3.20513997
47positive regulation of hair cycle (GO:0042635)3.17545147
48positive regulation of hair follicle development (GO:0051798)3.17545147
49phosphatidylinositol acyl-chain remodeling (GO:0036149)3.17222901
50positive regulation of p38MAPK cascade (GO:1900745)3.12350454
51ectoderm development (GO:0007398)3.09601082
52acyl-CoA biosynthetic process (GO:0071616)3.03897784
53thioester biosynthetic process (GO:0035384)3.03897784
54bone trabecula formation (GO:0060346)3.02632359
55trophectodermal cell differentiation (GO:0001829)3.02329507
56regulation of hair follicle development (GO:0051797)3.01810373
57gap junction assembly (GO:0016264)3.01476662
58detection of other organism (GO:0098543)3.01029534
59water homeostasis (GO:0030104)3.00652748
60epithelium development (GO:0060429)2.96014657
61positive regulation of interleukin-8 secretion (GO:2000484)2.90279966
62fatty-acyl-CoA metabolic process (GO:0035337)2.89013954
63phosphatidylserine acyl-chain remodeling (GO:0036150)2.87620265
64fatty acid elongation (GO:0030497)2.87294551
65regulation of hair cycle (GO:0042634)2.79484683
66atrioventricular valve morphogenesis (GO:0003181)2.76071996
67positive regulation of meiotic cell cycle (GO:0051446)2.74630356
68negative regulation of protein localization to plasma membrane (GO:1903077)2.74186505
69positive regulation of epidermis development (GO:0045684)2.72610935
70trophoblast giant cell differentiation (GO:0060707)2.65599293
71urogenital system development (GO:0001655)2.63395824
72phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.63197693
73respiratory tube development (GO:0030323)2.61289523
74cardiac epithelial to mesenchymal transition (GO:0060317)2.60320718
75epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.52855061
76positive regulation of glomerulus development (GO:0090193)2.51583607
77regulation of epidermal cell differentiation (GO:0045604)2.50035066
78ventricular cardiac muscle cell action potential (GO:0086005)2.49864220
79negative regulation of cell fate specification (GO:0009996)2.43840723
80regulation of epidermis development (GO:0045682)2.43653020
81regulation of p38MAPK cascade (GO:1900744)2.40956654
82defense response to Gram-negative bacterium (GO:0050829)2.39706847
83lateral sprouting from an epithelium (GO:0060601)2.35513526
84cell surface receptor signaling pathway involved in heart development (GO:0061311)2.35228681
85cellular response to fluid shear stress (GO:0071498)2.34452837
86response to fungus (GO:0009620)2.34040096
87skin development (GO:0043588)2.31471681
88wound healing, spreading of epidermal cells (GO:0035313)2.31402901
89negative regulation of stress fiber assembly (GO:0051497)2.29425345
90positive regulation of transforming growth factor beta production (GO:0071636)2.27630712
91positive regulation of epidermal cell differentiation (GO:0045606)2.26986035
92pattern specification involved in kidney development (GO:0061004)2.24453914
93regulation of mesenchymal cell apoptotic process (GO:2001053)2.24362572
94regulation of natural killer cell differentiation (GO:0032823)2.23850457
95cranial suture morphogenesis (GO:0060363)2.22860665
96positive regulation of SMAD protein import into nucleus (GO:0060391)2.22692684
97lymph vessel development (GO:0001945)2.22528035
98positive regulation of monocyte chemotaxis (GO:0090026)2.21509364
99alpha-linolenic acid metabolic process (GO:0036109)2.20729144
100mesenchymal cell differentiation involved in kidney development (GO:0072161)2.20546981
101mesenchymal cell differentiation involved in renal system development (GO:2001012)2.20546981
102phosphatidylserine metabolic process (GO:0006658)2.19575119
103hippo signaling (GO:0035329)2.18834980
104positive regulation of humoral immune response (GO:0002922)2.18256956
105primary alcohol metabolic process (GO:0034308)2.14439469
106phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.13786593
107regulation of mesoderm development (GO:2000380)2.13490892
108epithelial cell-cell adhesion (GO:0090136)2.12809242
109regulation of cardioblast differentiation (GO:0051890)2.11912865
110planar cell polarity pathway involved in neural tube closure (GO:0090179)2.11738377
111regulation of heart rate by cardiac conduction (GO:0086091)2.08910675
112cytoskeletal anchoring at plasma membrane (GO:0007016)2.07377571
113regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.03656248
114regulation of ruffle assembly (GO:1900027)2.02813086
115negative regulation of epidermis development (GO:0045683)2.00829306
116intermediate filament organization (GO:0045109)12.1521050
117keratinization (GO:0031424)11.8602499
118desmosome organization (GO:0002934)10.7026078
119virion attachment to host cell (GO:0019062)10.2412049
120adhesion of symbiont to host cell (GO:0044650)10.2412049
121aging (GO:0007568)1.98205600
122outflow tract septum morphogenesis (GO:0003148)1.98122355
123myotube differentiation (GO:0014902)1.97614615
124regulation of keratinocyte proliferation (GO:0010837)1.97355805
125cell communication involved in cardiac conduction (GO:0086065)1.97301950
126regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)1.95552307
127cell-substrate junction assembly (GO:0007044)1.93252498
128non-canonical Wnt signaling pathway (GO:0035567)1.90175537
129phosphatidylcholine acyl-chain remodeling (GO:0036151)1.87741922
130ephrin receptor signaling pathway (GO:0048013)1.86703687
131keratinocyte proliferation (GO:0043616)1.80998603
132establishment of planar polarity (GO:0001736)1.72935288
133establishment of tissue polarity (GO:0007164)1.72935288
134coronary vasculature morphogenesis (GO:0060977)1.72740150
135very long-chain fatty acid metabolic process (GO:0000038)1.71513560
136regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901211.69459982
137G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071991.67156531
138negative regulation of cell fate commitment (GO:0010454)1.66622438
139long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)1.66100683
140regulation of cardioblast proliferation (GO:0003264)1.65896924
141regulation of secondary heart field cardioblast proliferation (GO:0003266)1.65896924
142cardiac right ventricle morphogenesis (GO:0003215)1.64581649
143cardiac conduction (GO:0061337)1.63807181
144craniofacial suture morphogenesis (GO:0097094)1.62312503
145wound healing, spreading of cells (GO:0044319)1.61503158
146regulation of transforming growth factor beta2 production (GO:0032909)1.60422666

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.00413296
2CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.81164916
3P63_26484246_Chip-Seq_KERATINOCYTES_Human3.55693023
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.93748453
5CTCF_20526341_ChIP-Seq_ESCs_Human2.20324665
6NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse2.01828392
7BMI1_19503595_ChIP-Seq_MEFsC_Mouse2.01124589
8TP63_17297297_ChIP-ChIP_HaCaT_Human12.9643769
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.88646152
10KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.87736642
11KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.87736642
12KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.87736642
13SOX9_24532713_ChIP-Seq_HFSC_Mouse1.79730899
14E2F1_20622854_ChIP-Seq_HELA_Human1.74743927
15EGR1_19032775_ChIP-ChIP_M12_Human1.73490546
16AR_21909140_ChIP-Seq_LNCAP_Human1.72963527
17TAF2_19829295_ChIP-Seq_ESCs_Human1.72325392
18P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.68182705
19VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.67923912
20CSB_26484114_Chip-Seq_FIBROBLAST_Human1.65491068
21NANOG_20526341_ChIP-Seq_ESCs_Human1.60529947
22FOXO3_23340844_ChIP-Seq_DLD1_Human1.60308628
23ERG_20517297_ChIP-Seq_VCAP_Human1.58249238
24SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.57673669
25SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.57673669
26CTCF_27219007_Chip-Seq_Bcells_Human1.53442414
27RACK7_27058665_Chip-Seq_MCF-7_Human1.51678457
28P53_21459846_ChIP-Seq_SAOS-2_Human1.49581232
29TP53_20018659_ChIP-ChIP_R1E_Mouse1.49486532
30ESR1_21235772_ChIP-Seq_MCF-7_Human1.49058192
31TP63_22573176_ChIP-Seq_HFKS_Human1.47137947
32MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse1.44053829
33LXR_22292898_ChIP-Seq_THP-1_Human1.43156239
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42817434
35SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.42096886
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.40210097
37BCL6_27268052_Chip-Seq_Bcells_Human1.38821877
38ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.37633080
39ATF3_27146783_Chip-Seq_COLON_Human1.37206583
40UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.35949126
41RARG_19884340_ChIP-ChIP_MEFs_Mouse1.35821699
42YY1_22570637_ChIP-Seq_MALME-3M_Human1.35476783
43ESR1_20079471_ChIP-ChIP_T-47D_Human1.35473549
44BCOR_27268052_Chip-Seq_Bcells_Human1.31823751
45ESR2_21235772_ChIP-Seq_MCF-7_Human1.30299781
46TRIM28_21343339_ChIP-Seq_HEK293_Human1.27757817
47KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.24959168
48ARNT_22903824_ChIP-Seq_MCF-7_Human1.23404265
49AHR_22903824_ChIP-Seq_MCF-7_Human1.20933123
50PHF8_20622854_ChIP-Seq_HELA_Human1.18418622
51SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.17316015
52CEBPB_22108803_ChIP-Seq_LS180_Human1.16395279
53KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16274812
54SUZ12_27294783_Chip-Seq_ESCs_Mouse1.14963668
55GATA3_24758297_ChIP-Seq_MCF-7_Human1.14354334
56TP63_23658742_ChIP-Seq_EP156T_Human1.14162501
57P68_20966046_ChIP-Seq_HELA_Human1.13501670
58ELF1_20517297_ChIP-Seq_JURKAT_Human1.12511969
59UBF1/2_26484160_Chip-Seq_HMECs_Human1.12309770
60SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.11500552
61GATA4_25053715_ChIP-Seq_YYC3_Human1.08087963
62JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07570646
63TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06371049
64PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06339933
65RAC3_21632823_ChIP-Seq_H3396_Human1.05629439
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.05335924
67E2F1_17053090_ChIP-ChIP_MCF-7_Human1.04694850
68SMC4_20622854_ChIP-Seq_HELA_Human1.04443950
69JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04120201
70EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.04040959
71JARID2_20075857_ChIP-Seq_MESCs_Mouse1.03804924
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02225525
73KLF5_25053715_ChIP-Seq_YYC3_Human1.02080842
74CLOCK_20551151_ChIP-Seq_293T_Human1.01841381
75TP53_18474530_ChIP-ChIP_U2OS_Human1.00710703
76SA1_27219007_Chip-Seq_ERYTHROID_Human0.99910077
77ELK4_26923725_Chip-Seq_MESODERM_Mouse0.98995850
78GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98483648
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.94545439
80NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.93745603
81HTT_18923047_ChIP-ChIP_STHdh_Human0.93152633
82FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.93016666
83SOX2_21211035_ChIP-Seq_LN229_Human0.92802776
84SPI1_20517297_ChIP-Seq_HL60_Human0.92518791
85RUNX1_27514584_Chip-Seq_MCF-7_Human0.91741375
86CDX2_20551321_ChIP-Seq_CACO-2_Human0.90814048
87EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90289203
88GATA6_21074721_ChIP-Seq_CACO-2_Human0.89804512
89SOX2_20726797_ChIP-Seq_SW620_Human0.89686274
90TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89547467
91RXRA_24833708_ChIP-Seq_LIVER_Mouse0.89188586
92HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.88929961
93ZNF263_19887448_ChIP-Seq_K562_Human0.88834621
94RXR_22108803_ChIP-Seq_LS180_Human0.88069516
95ERG_21242973_ChIP-ChIP_JURKAT_Human0.87723293
96CDX2_19796622_ChIP-Seq_MESCs_Mouse0.87583820
97BMI1_23680149_ChIP-Seq_NPCS_Mouse0.87475729
98SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87446512
99RING1B_27294783_Chip-Seq_ESCs_Mouse0.86925426
100FOXH1_21741376_ChIP-Seq_ESCs_Human0.86894698
101GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86153148
102SMAD3_21741376_ChIP-Seq_HESCs_Human0.85932672
103AR_21572438_ChIP-Seq_LNCaP_Human0.84897128
104CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.83440717
105ZNF217_24962896_ChIP-Seq_MCF-7_Human0.81831355
106RNF2_27304074_Chip-Seq_ESCs_Mouse0.80539196
107TCF4_18268006_ChIP-ChIP_LS174T_Human0.80047339
108FOXA1_27270436_Chip-Seq_PROSTATE_Human0.78961219
109FOXA1_25329375_ChIP-Seq_VCAP_Human0.78961219
110HIF1A_21447827_ChIP-Seq_MCF-7_Human0.76780078
111ZFP281_18757296_ChIP-ChIP_E14_Mouse0.76013309
112FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.75552828
113EZH2_27294783_Chip-Seq_ESCs_Mouse0.75514058
114* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.74801811
115ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.74505919
116ELK3_25401928_ChIP-Seq_HUVEC_Human0.74303821
117AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.73604516
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.72980493
119TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.72972660
120KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.72707604
121PPARA_22158963_ChIP-Seq_LIVER_Mouse0.72670712
122SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.71928766
123ELF5_23300383_ChIP-Seq_T47D_Human0.71252893
124GATA6_25053715_ChIP-Seq_YYC3_Human0.70564463
125STAT6_21828071_ChIP-Seq_BEAS2B_Human0.69786587
126CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.66267501
127TCF3_18692474_ChIP-Seq_MEFs_Mouse0.65010051
128SMAD3_21741376_ChIP-Seq_EPCs_Human0.64105768
129NANOG_18692474_ChIP-Seq_MEFs_Mouse0.63000010
130AUTS2_25519132_ChIP-Seq_293T-REX_Human0.61812463
131SMAD4_21741376_ChIP-Seq_EPCs_Human0.61292478
132FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.61037514
133PPAR_26484153_Chip-Seq_NCI-H1993_Human0.60739600
134GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.60173017
135HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.59177812
136CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.59011646
137SMAD4_21741376_ChIP-Seq_ESCs_Human0.58656222
138TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.58127434

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000579_abnormal_nail_morphology7.76304664
2MP0002098_abnormal_vibrissa_morphology6.83968986
3MP0000647_abnormal_sebaceous_gland6.19521356
4MP0002796_impaired_skin_barrier6.01996019
5MP0005275_abnormal_skin_tensile5.29910879
6MP0010234_abnormal_vibrissa_follicle5.01891600
7MP0000383_abnormal_hair_follicle4.67405603
8MP0010678_abnormal_skin_adnexa4.15067382
9MP0000377_abnormal_hair_follicle3.99228512
10MP0003878_abnormal_ear_physiology3.80822132
11MP0005377_hearing/vestibular/ear_phenot3.80822132
12MP0005501_abnormal_skin_physiology3.76377246
13MP0003705_abnormal_hypodermis_morpholog3.68522323
14MP0000427_abnormal_hair_cycle3.50275371
15MP0002254_reproductive_system_inflammat3.11110875
16MP0001216_abnormal_epidermal_layer2.72315395
17MP0004381_abnormal_hair_follicle2.51406395
18MP0010771_integument_phenotype2.35656512
19MP0004947_skin_inflammation2.32407709
20MP0000367_abnormal_coat/_hair2.28956001
21MP0002060_abnormal_skin_morphology2.25715743
22MP0003453_abnormal_keratinocyte_physiol2.20981545
23MP0001243_abnormal_dermal_layer2.16552133
24MP0002234_abnormal_pharynx_morphology1.89423754
25MP0000467_abnormal_esophagus_morphology1.84213449
26MP0000762_abnormal_tongue_morphology1.52793753
27MP0009931_abnormal_skin_appearance1.51419617
28MP0003566_abnormal_cell_adhesion1.47121360
29MP0001188_hyperpigmentation1.46408638
30MP0009053_abnormal_anal_canal1.46244671
31MP0003941_abnormal_skin_development1.33476334
32MP0005409_darkened_coat_color1.31996644
33MP0004782_abnormal_surfactant_physiolog1.11881900
34MP0001485_abnormal_pinna_reflex1.05876594
35MP0005257_abnormal_intraocular_pressure1.05313944
36MP0001191_abnormal_skin_condition1.02794772
37MP0003890_abnormal_embryonic-extraembry0.95609889
38MP0004885_abnormal_endolymph0.95511129
39MP0004185_abnormal_adipocyte_glucose0.94519530
40MP0004264_abnormal_extraembryonic_tissu0.94417192
41MP0008438_abnormal_cutaneous_collagen0.84653217
42MP0002095_abnormal_skin_pigmentation0.84387539
43MP0001851_eye_inflammation0.80747848
44MP0001346_abnormal_lacrimal_gland0.71074667
45MP0001661_extended_life_span0.70861959
46MP0003567_abnormal_fetal_cardiomyocyte0.70003458
47MP0001849_ear_inflammation0.68588274
48MP0002877_abnormal_melanocyte_morpholog0.67397103
49MP0000566_synostosis0.67026734
50MP0001340_abnormal_eyelid_morphology0.66331479
51MP0003315_abnormal_perineum_morphology0.63522795
52MP0010030_abnormal_orbit_morphology0.59606618
53MP0000627_abnormal_mammary_gland0.57917699
54MP0005647_abnormal_sex_gland0.56693243
55MP0002282_abnormal_trachea_morphology0.54528563
56MP0003191_abnormal_cellular_cholesterol0.52838169
57MP0005023_abnormal_wound_healing0.52454952
58MP0005451_abnormal_body_composition0.52398119
59MP0003755_abnormal_palate_morphology0.50953177
60MP0009672_abnormal_birth_weight0.47656475
61MP0001784_abnormal_fluid_regulation0.47572867
62MP0006035_abnormal_mitochondrial_morpho0.44512682
63MP0004957_abnormal_blastocyst_morpholog0.44348845
64MP0002970_abnormal_white_adipose0.44012450
65MP0003119_abnormal_digestive_system0.43912408
66MP0002127_abnormal_cardiovascular_syste0.41568628
67MP0002111_abnormal_tail_morphology0.39665219
68MP0001293_anophthalmia0.37422694
69MP0002249_abnormal_larynx_morphology0.37345872
70MP0004272_abnormal_basement_membrane0.37014665
71MP0010352_gastrointestinal_tract_polyps0.36918323
72MP0008004_abnormal_stomach_pH0.36370889
73MP0005197_abnormal_uvea_morphology0.35625414
74MP0001177_atelectasis0.34563740
75MP0009379_abnormal_foot_pigmentation0.34033752
76MP0003385_abnormal_body_wall0.32997546
77MP0009333_abnormal_splenocyte_physiolog0.32597297
78MP0000537_abnormal_urethra_morphology0.31767109
79MP0002177_abnormal_outer_ear0.31766360
80MP0009703_decreased_birth_body0.31306485
81MP0003942_abnormal_urinary_system0.31276902
82MP0006054_spinal_hemorrhage0.30608480
83MP0005075_abnormal_melanosome_morpholog0.30598739
84MP0002084_abnormal_developmental_patter0.29189673
85MP0000534_abnormal_ureter_morphology0.28767184
86MP0000678_abnormal_parathyroid_gland0.28251796
87MP0002086_abnormal_extraembryonic_tissu0.27885713
88MP0002697_abnormal_eye_size0.27390972
89MP0005380_embryogenesis_phenotype0.25960731
90MP0001672_abnormal_embryogenesis/_devel0.25960731
91MP0003937_abnormal_limbs/digits/tail_de0.25656460
92MP0003300_gastrointestinal_ulcer0.25566038
93MP0005248_abnormal_Harderian_gland0.25223107
94MP0003950_abnormal_plasma_membrane0.24930202
95MP0004197_abnormal_fetal_growth/weight/0.24385101
96MP0000465_gastrointestinal_hemorrhage0.23607685
97MP0003763_abnormal_thymus_physiology0.23581120
98MP0010094_abnormal_chromosome_stability0.22475792
99MP0000432_abnormal_head_morphology0.21701924
100MP0009840_abnormal_foam_cell0.20812635
101MP0001730_embryonic_growth_arrest0.20220088
102MP0005388_respiratory_system_phenotype0.19714565
103MP0002133_abnormal_respiratory_system0.19714565
104MP0002092_abnormal_eye_morphology0.19086859
105MP0000015_abnormal_ear_pigmentation0.18200590
106MP0005666_abnormal_adipose_tissue0.17913014
107MP0010307_abnormal_tumor_latency0.17692420
108MP0005367_renal/urinary_system_phenotyp0.17604105
109MP0000516_abnormal_urinary_system0.17604105
110MP0003935_abnormal_craniofacial_develop0.17095228
111MP0005076_abnormal_cell_differentiation0.17007860
112MP0003329_amyloid_beta_deposits0.16844600
113MP0002166_altered_tumor_susceptibility0.16559072
114MP0009384_cardiac_valve_regurgitation0.15993170
115MP0005375_adipose_tissue_phenotype0.15905267
116MP0004019_abnormal_vitamin_homeostasis0.15839586
117MP0002006_tumorigenesis0.15736388
118MP0003448_altered_tumor_morphology0.15065070
119MP0004742_abnormal_vestibular_system0.14548598
120MP0001879_abnormal_lymphatic_vessel0.14177139
121MP0005193_abnormal_anterior_eye0.11824243
122MP0003638_abnormal_response/metabolism_0.11294145
123MP0004858_abnormal_nervous_system0.10787235
124MP0002233_abnormal_nose_morphology0.10751193
125MP0001958_emphysema0.10290650
126MP0003045_fibrosis0.10178634
127MP0000733_abnormal_muscle_development0.09570290
128MP0005508_abnormal_skeleton_morphology0.09143983
129MP0002009_preneoplasia0.09017526
130MP0003011_delayed_dark_adaptation0.08560393
131MP0000462_abnormal_digestive_system0.07888445
132MP0000751_myopathy0.07812959
133MP0000604_amyloidosis0.07666330
134MP0002896_abnormal_bone_mineralization0.06926786
135MP0000428_abnormal_craniofacial_morphol0.06726902

Predicted human phenotypes

RankGene SetZ-score
1Brittle hair (HP:0002299)9.41869135
2Pili torti (HP:0003777)9.30026578
3Nail dystrophy (HP:0008404)6.99584463
4Abnormality of nail color (HP:0100643)6.89626607
5Abnormal hair laboratory examination (HP:0003328)5.87012566
6Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.75876934
7Fragile nails (HP:0001808)5.73891214
8Alopecia of scalp (HP:0002293)5.24844166
9Palmoplantar hyperkeratosis (HP:0000972)5.05463293
10Onycholysis (HP:0001806)5.00636876
11Fine hair (HP:0002213)4.96402698
12Follicular hyperkeratosis (HP:0007502)4.84071994
13Increased IgE level (HP:0003212)4.78182473
14Thick nail (HP:0001805)4.77510623
15Palmar hyperkeratosis (HP:0010765)4.75996085
16Absent eyebrow (HP:0002223)4.69777457
17Plantar hyperkeratosis (HP:0007556)4.63633009
18Absent hair (HP:0002298)4.50152611
19Right ventricular cardiomyopathy (HP:0011663)4.45357058
20Abnormality of secondary sexual hair (HP:0009888)4.27748429
21Abnormality of the axillary hair (HP:0100134)4.27748429
22Sparse eyelashes (HP:0000653)3.74912768
23Oral leukoplakia (HP:0002745)3.72632414
24Erythema (HP:0010783)3.65301410
25Milia (HP:0001056)3.37178713
26Abnormality of the frontal sinuses (HP:0002687)3.17555506
27Parakeratosis (HP:0001036)3.14907094
28Amelogenesis imperfecta (HP:0000705)3.12748367
29Erythroderma (HP:0001019)3.01359551
30Congenital, generalized hypertrichosis (HP:0004540)2.89645495
31Curly hair (HP:0002212)2.82863608
32Ridged nail (HP:0001807)2.71859155
33Congenital ichthyosiform erythroderma (HP:0007431)2.64362138
34Intention tremor (HP:0002080)2.59527963
35Abnormal blistering of the skin (HP:0008066)2.57810181
36Aplasia cutis congenita (HP:0001057)2.56212699
37Neck muscle weakness (HP:0000467)2.45475074
38Natal tooth (HP:0000695)2.44942955
39Advanced eruption of teeth (HP:0006288)2.38946853
40Dry hair (HP:0011359)2.35937537
41Torticollis (HP:0000473)2.26335747
42Hypohidrosis (HP:0000966)2.19018087
43Corneal erosion (HP:0200020)2.16223420
44Palmoplantar keratoderma (HP:0000982)2.13781357
45Ventricular tachycardia (HP:0004756)2.10565334
46Pruritus (HP:0000989)2.00943874
47Hypotrichosis (HP:0001006)14.0079976
48Woolly hair (HP:0002224)11.3002605
49Abnormality of hair growth rate (HP:0011363)10.3655256
50Slow-growing hair (HP:0002217)10.3655256
51Hamartoma of the eye (HP:0010568)1.96700809
52Abnormal umbilical cord blood vessels (HP:0011403)1.94482625
53Single umbilical artery (HP:0001195)1.94482625
54Abnormality of the fetal cardiovascular system (HP:0010948)1.94482625
55Abnormal pancreas size (HP:0012094)1.94027956
56Craniofacial dystonia (HP:0012179)1.89465118
57Ventricular fibrillation (HP:0001663)1.85253340
58Difficulty walking (HP:0002355)1.85182762
59Concave nail (HP:0001598)1.84879634
60Abnormality of the salivary glands (HP:0010286)1.84347514
61Abnormality of permanent molar morphology (HP:0011071)1.80816174
62Abnormality of the dental root (HP:0006486)1.80816174
63Taurodontia (HP:0000679)1.80816174
64Abnormality of the pupil (HP:0000615)1.80772573
65Abnormality of the parietal bone (HP:0002696)1.79413236
66Abnormality of molar morphology (HP:0011070)1.79076071
67Abnormality of molar (HP:0011077)1.79076071
68Absent eyelashes (HP:0000561)1.77072685
69Abnormality of dental color (HP:0011073)1.74473041
70Furrowed tongue (HP:0000221)1.73485058
71Hypoplastic labia majora (HP:0000059)1.72975140
72Focal dystonia (HP:0004373)1.72526339
73Recurrent corneal erosions (HP:0000495)1.71919173
74Widely patent fontanelles and sutures (HP:0004492)1.67720940
75Fatigable weakness (HP:0003473)1.67144510
76Abnormality of the neuromuscular junction (HP:0003398)1.67144510
77Conjunctival hamartoma (HP:0100780)1.66535828
78Hyporeflexia of lower limbs (HP:0002600)1.66295675
79Blepharitis (HP:0000498)1.65013306
80Abnormality of placental membranes (HP:0011409)1.61416936
81Amniotic constriction ring (HP:0009775)1.61416936
82Abnormality of the dental pulp (HP:0006479)1.58864679
83Bilateral sensorineural hearing impairment (HP:0008619)1.56720613
84Abnormality of the labia majora (HP:0012881)1.55619446
85Lip pit (HP:0100267)1.55169590
86Carious teeth (HP:0000670)1.51921823
87Acanthosis nigricans (HP:0000956)1.50933538
88Split foot (HP:0001839)1.50555860
89Anonychia (HP:0001798)1.49302290
90Septate vagina (HP:0001153)1.48738993
91Microglossia (HP:0000171)1.47854383
92Unilateral renal agenesis (HP:0000122)1.46964215
93Sudden death (HP:0001699)1.46821081
94Keratoconjunctivitis sicca (HP:0001097)1.46139005
95Proximal placement of thumb (HP:0009623)1.45630426
96Dehydration (HP:0001944)1.44485983
97Ectropion (HP:0000656)1.44376573
98Atrophic scars (HP:0001075)1.42383117
99Gangrene (HP:0100758)1.41350564
100Pustule (HP:0200039)1.41219345
101Myelomeningocele (HP:0002475)1.40908299
102Laryngomalacia (HP:0001601)1.38395638
103Abnormality of the aortic arch (HP:0012303)1.38177497
104Hypergammaglobulinemia (HP:0010702)1.38169509
105Craniofacial hyperostosis (HP:0004493)1.38086534
106Autoamputation (HP:0001218)1.38063839
107Urticaria (HP:0001025)1.37703478
108Abnormality of small intestinal villus morphology (HP:0011472)1.37077402
109Villous atrophy (HP:0011473)1.37077402
110Abnormality of the fingernails (HP:0001231)1.35946452
111Coarse hair (HP:0002208)1.34847382
112Distal lower limb muscle weakness (HP:0009053)1.34170891
113Deviation of the thumb (HP:0009603)1.33905688
114Round ear (HP:0100830)1.33862108
115Achilles tendon contracture (HP:0001771)1.33499289
116Abnormalities of placenta or umbilical cord (HP:0001194)1.33419369
117Heterogeneous (HP:0001425)1.32081811
118Paralysis (HP:0003470)1.30837983
119Neonatal death (HP:0003811)1.30278022
120Keratoconjunctivitis (HP:0001096)1.30037115
121Abnormality of the umbilical cord (HP:0010881)1.29141875
122Type 1 muscle fiber predominance (HP:0003803)1.28429281
123Delayed CNS myelination (HP:0002188)1.24986905
124Abnormality of the Achilles tendon (HP:0005109)1.24760893
125Increased connective tissue (HP:0009025)1.24508954
126Sparse scalp hair (HP:0002209)1.23958690
127Corneal dystrophy (HP:0001131)1.21105878
128Lack of skin elasticity (HP:0100679)1.20088427
129Neonatal onset (HP:0003623)1.19849363
130Hyperhidrosis (HP:0000975)1.19800090
131Selective tooth agenesis (HP:0001592)1.19372241
132Abnormality of the gastric mucosa (HP:0004295)1.19316021
133Short middle phalanx of the 5th finger (HP:0004220)1.16416257
134Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.13331313
135Breast hypoplasia (HP:0003187)1.12023263

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK46.31679128
2FER4.26571293
3EPHA24.25798701
4MAPKAPK33.90962788
5ERN13.82589457
6MAP3K63.44941309
7EPHB23.13113989
8TAOK12.97637573
9LATS12.81809105
10AKT32.76627060
11MAP3K32.70718269
12TRIB32.64494564
13MAP3K22.43205644
14EIF2AK32.40404897
15STK392.29490703
16TTN2.02800826
17MAP3K111.98816933
18PIK3CG1.96082567
19RPS6KB21.91682030
20STK241.89042079
21EEF2K1.76762070
22TESK21.72216451
23EPHB11.70075138
24LATS21.65676176
25MAP2K61.61950077
26FGFR21.55373619
27WNK41.54779083
28BCR1.53084265
29OXSR11.47143681
30TSSK61.46844769
31STK101.40913407
32WEE11.40493722
33RIPK11.36985985
34MST1R1.34971906
35FGFR41.34023257
36FGFR11.31070000
37TTK1.28758227
38FGFR31.28284646
39SIK11.27518032
40MAP3K11.25633100
41NME11.25296063
42CDK61.23721835
43MAP3K121.22463150
44PDGFRA1.19528543
45BMX1.16168837
46KSR21.13878482
47MAP2K31.10257397
48PKN21.07849348
49BRSK21.07793447
50PTK61.06550428
51MAPKAPK21.04508113
52BLK1.04182262
53ABL21.03581282
54LRRK21.02138220
55MAP3K71.01612612
56PBK0.96311707
57MKNK20.88763288
58RPS6KA40.88598205
59PRKAA20.86186308
60PTK20.85004845
61NME20.83056606
62STK38L0.81369332
63DYRK1B0.80308369
64OBSCN0.79993880
65BRAF0.79676778
66STK380.79507175
67MAP3K90.79419472
68EIF2AK20.77840390
69MET0.75583536
70MAP2K40.74589080
71MAP2K10.73372944
72TESK10.72292023
73DDR20.72289690
74PDK20.69116316
75PRKD10.67703572
76PIM20.67303405
77PAK40.66825793
78TRPM70.64945109
79SRPK10.64818057
80PAK30.64721072
81MAP3K100.64623422
82ERBB40.60932437
83EPHA30.60377809
84TAF10.58132301
85ARAF0.57774522
86PRKCI0.56446638
87EIF2AK10.54517054
88NTRK20.54139784
89ERBB20.52905660
90MST40.52819408
91RET0.52807521
92MAP3K50.52367936
93JAK10.52322465
94TYRO30.51499632
95NEK20.50482161
96MKNK10.50418056
97TGFBR10.50173413
98CDK190.49877071
99PAK20.48832578
100TYK20.47877013
101PKN10.47594221
102PRKCH0.45963920
103MATK0.45646309
104RPS6KA10.45505785
105ERBB30.43208265
106NEK10.42903167
107ALK0.42142820
108IRAK20.41103506
109GSK3A0.39523938
110PAK60.39084360
111MAPK120.38285010
112CSNK1E0.38002834
113AURKB0.37830993
114DAPK20.36825439
115TGFBR20.33662071
116JAK20.33640839
117LIMK10.33329309
118KDR0.33116053
119MAP3K80.31449484
120MAP2K20.30824868
121CDK70.30460816
122STK30.29378005
123FYN0.28956900
124MYLK0.27778333
125ACVR1B0.27646727
126ADRBK10.27556121
127PHKG20.27161665
128PHKG10.27161665
129SRC0.25711480
130ILK0.25541944
131PLK10.24708309
132CLK10.23367538
133MTOR0.22822341
134CSNK1A10.22740837
135DAPK30.22189664
136CSNK1D0.21921553
137MARK30.21550510
138STK110.21229593
139PDGFRB0.21146317
140RPS6KB10.20821210
141ABL10.19255495
142IKBKB0.18230113
143IKBKE0.18205475
144DMPK0.17180051
145CDC70.15649177
146IRAK10.15379670
147BRD40.14778706
148RPS6KC10.13792337
149RPS6KL10.13792337

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005924.57367731
2Linoleic acid metabolism_Homo sapiens_hsa005914.52360887
3Vitamin digestion and absorption_Homo sapiens_hsa049773.30845306
4Fat digestion and absorption_Homo sapiens_hsa049752.88615264
5Fatty acid elongation_Homo sapiens_hsa000622.88187983
6Fatty acid biosynthesis_Homo sapiens_hsa000612.40066864
7Ether lipid metabolism_Homo sapiens_hsa005652.38004934
8Basal cell carcinoma_Homo sapiens_hsa052172.34118838
9Collecting duct acid secretion_Homo sapiens_hsa049662.10964455
10Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.00552370
11Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.77704975
12Arachidonic acid metabolism_Homo sapiens_hsa005901.74374213
13Phenylalanine metabolism_Homo sapiens_hsa003601.73918092
14VEGF signaling pathway_Homo sapiens_hsa043701.72360917
15Melanogenesis_Homo sapiens_hsa049161.60174523
16Axon guidance_Homo sapiens_hsa043601.55716728
17Retinol metabolism_Homo sapiens_hsa008301.47805838
182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.47604543
19Caffeine metabolism_Homo sapiens_hsa002321.45235745
20Hedgehog signaling pathway_Homo sapiens_hsa043401.44872093
21Bladder cancer_Homo sapiens_hsa052191.44713756
22Proteoglycans in cancer_Homo sapiens_hsa052051.39327028
23Hippo signaling pathway_Homo sapiens_hsa043901.37988673
24Glioma_Homo sapiens_hsa052141.37653249
25Histidine metabolism_Homo sapiens_hsa003401.37585034
26Thyroid cancer_Homo sapiens_hsa052161.36714291
27Ovarian steroidogenesis_Homo sapiens_hsa049131.35990579
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.26838626
29Tight junction_Homo sapiens_hsa045301.25508191
30Acute myeloid leukemia_Homo sapiens_hsa052211.24216144
31Vascular smooth muscle contraction_Homo sapiens_hsa042701.24043953
32GnRH signaling pathway_Homo sapiens_hsa049121.23244097
33Dorso-ventral axis formation_Homo sapiens_hsa043201.22160934
34Adherens junction_Homo sapiens_hsa045201.20273988
35ECM-receptor interaction_Homo sapiens_hsa045121.17927559
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15694982
37Mineral absorption_Homo sapiens_hsa049781.13057515
38Vibrio cholerae infection_Homo sapiens_hsa051101.07120089
39Steroid biosynthesis_Homo sapiens_hsa001001.05411373
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.04480616
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.02656044
42Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02621264
43NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02503888
44Pancreatic secretion_Homo sapiens_hsa049721.02295401
45PPAR signaling pathway_Homo sapiens_hsa033201.02176602
46Long-term potentiation_Homo sapiens_hsa047200.96814395
47Endometrial cancer_Homo sapiens_hsa052130.96399118
48Non-small cell lung cancer_Homo sapiens_hsa052230.93029457
49Leukocyte transendothelial migration_Homo sapiens_hsa046700.92694939
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90983381
51Proteasome_Homo sapiens_hsa030500.90168346
52Amoebiasis_Homo sapiens_hsa051460.89632680
53Pertussis_Homo sapiens_hsa051330.86806376
54Nitrogen metabolism_Homo sapiens_hsa009100.85779769
55Wnt signaling pathway_Homo sapiens_hsa043100.85245133
56RNA transport_Homo sapiens_hsa030130.84310183
57Glycerophospholipid metabolism_Homo sapiens_hsa005640.83819511
58Tyrosine metabolism_Homo sapiens_hsa003500.83485282
59Long-term depression_Homo sapiens_hsa047300.82465420
60Ras signaling pathway_Homo sapiens_hsa040140.82009782
61Estrogen signaling pathway_Homo sapiens_hsa049150.81070986
62Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.78714045
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76295817
64Glycerolipid metabolism_Homo sapiens_hsa005610.75666115
65Cyanoamino acid metabolism_Homo sapiens_hsa004600.75472425
66Serotonergic synapse_Homo sapiens_hsa047260.74521477
67MicroRNAs in cancer_Homo sapiens_hsa052060.74083387
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70081766
69Oocyte meiosis_Homo sapiens_hsa041140.68912269
70Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67713171
71Non-homologous end-joining_Homo sapiens_hsa034500.66952904
72beta-Alanine metabolism_Homo sapiens_hsa004100.66600281
73Gastric acid secretion_Homo sapiens_hsa049710.66493029
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.66350159
75Sulfur metabolism_Homo sapiens_hsa009200.66071508
76Insulin resistance_Homo sapiens_hsa049310.65873983
77Focal adhesion_Homo sapiens_hsa045100.65753864
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65360060
79Hepatitis C_Homo sapiens_hsa051600.63840467
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63667767
81Staphylococcus aureus infection_Homo sapiens_hsa051500.63308529
82Renin secretion_Homo sapiens_hsa049240.62786680
83Protein digestion and absorption_Homo sapiens_hsa049740.61942623
84Cell cycle_Homo sapiens_hsa041100.61243498
85TGF-beta signaling pathway_Homo sapiens_hsa043500.60206098
86Choline metabolism in cancer_Homo sapiens_hsa052310.60089224
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.59900498
88Pyruvate metabolism_Homo sapiens_hsa006200.58887003
89Rap1 signaling pathway_Homo sapiens_hsa040150.58779731
90Phototransduction_Homo sapiens_hsa047440.57648160
91Fatty acid metabolism_Homo sapiens_hsa012120.57513026
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.56476013
93Propanoate metabolism_Homo sapiens_hsa006400.56020128
94Platelet activation_Homo sapiens_hsa046110.55384218
95Salmonella infection_Homo sapiens_hsa051320.54540104
96Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.54500758
97Endocytosis_Homo sapiens_hsa041440.54409786
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54212804
99Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53997124
100Renal cell carcinoma_Homo sapiens_hsa052110.53636028
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.53501001
102Gap junction_Homo sapiens_hsa045400.53293446
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.49814243
104ErbB signaling pathway_Homo sapiens_hsa040120.49375391
105Toxoplasmosis_Homo sapiens_hsa051450.48333438
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47986679
107Oxytocin signaling pathway_Homo sapiens_hsa049210.47174968
108Chronic myeloid leukemia_Homo sapiens_hsa052200.46747376
109p53 signaling pathway_Homo sapiens_hsa041150.44912417
110Salivary secretion_Homo sapiens_hsa049700.44875785
111Notch signaling pathway_Homo sapiens_hsa043300.44811593
112Base excision repair_Homo sapiens_hsa034100.43611611
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42963675
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.42247524
115Steroid hormone biosynthesis_Homo sapiens_hsa001400.41841911
116Tuberculosis_Homo sapiens_hsa051520.41082391
117Melanoma_Homo sapiens_hsa052180.40696153
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40114052
119Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.39699779
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39532558
121Prolactin signaling pathway_Homo sapiens_hsa049170.38909989
122Fatty acid degradation_Homo sapiens_hsa000710.38690445
123Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37830495
124Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.37609558
125Insulin signaling pathway_Homo sapiens_hsa049100.37543190
126Pathways in cancer_Homo sapiens_hsa052000.37094404
127Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.37071758
128Chemical carcinogenesis_Homo sapiens_hsa052040.35590953
129Peroxisome_Homo sapiens_hsa041460.35148922
130Sphingolipid metabolism_Homo sapiens_hsa006000.34248182
131Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34194995
132Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34185681
133Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33723900
134Prion diseases_Homo sapiens_hsa050200.33463159
135Legionellosis_Homo sapiens_hsa051340.33095211
136Circadian rhythm_Homo sapiens_hsa047100.29994862
137mRNA surveillance pathway_Homo sapiens_hsa030150.27011174
138Renin-angiotensin system_Homo sapiens_hsa046140.26088657
139Mismatch repair_Homo sapiens_hsa034300.22241738
140Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.20909453

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