PRRC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)8.01679218
2COPI coating of Golgi vesicle (GO:0048205)8.01679218
3maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.74459179
4nuclear pore complex assembly (GO:0051292)5.31184617
5protein retention in ER lumen (GO:0006621)5.29734182
6COPII vesicle coating (GO:0048208)5.27623779
7activation of signaling protein activity involved in unfolded protein response (GO:0006987)5.04646315
8positive regulation of nuclease activity (GO:0032075)4.87554257
9nuclear pore organization (GO:0006999)4.86031562
10regulation of nuclease activity (GO:0032069)4.44179088
11endoplasmic reticulum unfolded protein response (GO:0030968)4.33529643
12exocrine pancreas development (GO:0031017)4.33231213
13retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)4.20689115
14cellular response to unfolded protein (GO:0034620)4.17152222
15folic acid-containing compound biosynthetic process (GO:0009396)4.12545544
16cellular response to topologically incorrect protein (GO:0035967)4.02713761
17ER-nucleus signaling pathway (GO:0006984)3.94439310
18pore complex assembly (GO:0046931)3.81915151
194-hydroxyproline metabolic process (GO:0019471)3.79363069
20vesicle coating (GO:0006901)3.65246228
21proline biosynthetic process (GO:0006561)3.53232147
22response to endoplasmic reticulum stress (GO:0034976)3.40576167
23mitotic sister chromatid cohesion (GO:0007064)3.39583950
24protein maturation by protein folding (GO:0022417)3.35510716
25UDP-N-acetylglucosamine metabolic process (GO:0006047)3.28698957
26response to unfolded protein (GO:0006986)3.23043054
27ER overload response (GO:0006983)3.20658456
28peptidyl-proline hydroxylation (GO:0019511)3.19879022
29paraxial mesoderm development (GO:0048339)3.19020420
30response to topologically incorrect protein (GO:0035966)3.13567000
31ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.09463383
32intestinal cholesterol absorption (GO:0030299)3.06623680
33protein carboxylation (GO:0018214)3.06611436
34peptidyl-glutamic acid carboxylation (GO:0017187)3.06611436
35L-alpha-amino acid transmembrane transport (GO:1902475)3.05488147
36peptidyl-asparagine modification (GO:0018196)3.01878692
37protein N-linked glycosylation via asparagine (GO:0018279)3.00896962
38desmosome organization (GO:0002934)3.00399381
39hippo signaling (GO:0035329)2.99107603
40cell adhesion mediated by integrin (GO:0033627)2.97835803
41glandular epithelial cell development (GO:0002068)2.96260076
42maternal placenta development (GO:0001893)2.95772435
43protein hydroxylation (GO:0018126)2.94911768
44endocrine pancreas development (GO:0031018)2.93114236
45regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.90474255
46positive regulation of SMAD protein import into nucleus (GO:0060391)2.89525345
47sequestering of extracellular ligand from receptor (GO:0035581)2.87120305
48glucocorticoid receptor signaling pathway (GO:0042921)2.86671387
49pteridine-containing compound biosynthetic process (GO:0042559)2.83761838
50type B pancreatic cell development (GO:0003323)2.83354900
51intestinal epithelial cell development (GO:0060576)2.82310796
52protein localization to kinetochore (GO:0034501)2.78856812
53ribosome assembly (GO:0042255)2.78071254
54cellular response to vitamin D (GO:0071305)2.77390372
55protein heterotrimerization (GO:0070208)2.77085372
56tetrahydrofolate metabolic process (GO:0046653)2.75824017
57regulation of SMAD protein import into nucleus (GO:0060390)2.75186701
58skin morphogenesis (GO:0043589)2.75143175
59columnar/cuboidal epithelial cell development (GO:0002066)2.73738515
60signal peptide processing (GO:0006465)2.73491772
61regulation of transforming growth factor beta2 production (GO:0032909)2.73481032
62valine metabolic process (GO:0006573)2.71047851
63tRNA aminoacylation for protein translation (GO:0006418)2.70058550
64keratan sulfate catabolic process (GO:0042340)2.69922313
65protein N-linked glycosylation (GO:0006487)2.69555367
66mitotic nuclear envelope disassembly (GO:0007077)2.68030350
67intestinal absorption (GO:0050892)2.67588468
68collagen fibril organization (GO:0030199)2.66846201
69polarized epithelial cell differentiation (GO:0030859)2.64979866
70tRNA aminoacylation (GO:0043039)2.64439153
71amino acid activation (GO:0043038)2.64439153
72regulation of transforming growth factor beta production (GO:0071634)2.61984373
73nucleotide-sugar biosynthetic process (GO:0009226)2.61611978
74regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.61430778
75sequestering of metal ion (GO:0051238)2.61319691
76regulation of translational fidelity (GO:0006450)2.60968655
77positive regulation of hormone biosynthetic process (GO:0046886)2.60622262
78nuclear envelope disassembly (GO:0051081)2.60403531
79membrane disassembly (GO:0030397)2.60403531
80anterior/posterior axis specification, embryo (GO:0008595)2.60303245
81positive regulation of cell size (GO:0045793)2.58626205
82positive regulation of histone deacetylation (GO:0031065)2.58205399
83mitotic metaphase plate congression (GO:0007080)2.57367265
84mitotic chromosome condensation (GO:0007076)2.53906105
85regulation of centriole replication (GO:0046599)2.53431928
86glandular epithelial cell differentiation (GO:0002067)2.53097115
87chondrocyte development (GO:0002063)2.52816134
88epithelial cell-cell adhesion (GO:0090136)2.52081505
89negative regulation of keratinocyte proliferation (GO:0010839)2.52020148
90formation of translation preinitiation complex (GO:0001731)2.51547911
91macroautophagy (GO:0016236)2.51301361
92pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.48629584
93UMP metabolic process (GO:0046049)2.48629584
94pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.48629584
95UMP biosynthetic process (GO:0006222)2.48629584
96apoptotic cell clearance (GO:0043277)2.46637997
97chondrocyte proliferation (GO:0035988)2.46601848
98tooth mineralization (GO:0034505)2.46151772
99establishment of integrated proviral latency (GO:0075713)2.44711307
100cellular protein complex localization (GO:0034629)2.44111985
101tricarboxylic acid metabolic process (GO:0072350)2.43628123
102cellular response to nutrient (GO:0031670)2.43458650
103ER to Golgi vesicle-mediated transport (GO:0006888)2.42757704
104protein localization to chromosome, centromeric region (GO:0071459)2.42582654
105glycine metabolic process (GO:0006544)2.40856933
106regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.40578576
107hormone catabolic process (GO:0042447)2.40073494
108peptide catabolic process (GO:0043171)2.39727680
109regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.39169906
110cellular response to vitamin (GO:0071295)2.36464396
111regulation of cardioblast differentiation (GO:0051890)2.35316553
112metaphase plate congression (GO:0051310)2.32801078
113sister chromatid segregation (GO:0000819)2.32422942
114Golgi organization (GO:0007030)2.32041478
115protein autoprocessing (GO:0016540)2.31332347
116bundle of His cell to Purkinje myocyte communication (GO:0086069)2.30883727
117positive regulation of macrophage activation (GO:0043032)2.30464611
118peptide hormone processing (GO:0016486)2.30097356
119mitotic cytokinesis (GO:0000281)2.29929309
120negative regulation of DNA repair (GO:0045738)2.28411450
121dorsal/ventral axis specification (GO:0009950)2.28145065
122protein localization to microtubule (GO:0035372)2.28120807
123gap junction assembly (GO:0016264)2.26434563
124proline metabolic process (GO:0006560)2.25772638
125SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.25507250
126sulfur amino acid catabolic process (GO:0000098)2.24501169
127GDP-mannose metabolic process (GO:0019673)2.24252543
128positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.23758270
129positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.23758270
130positive regulation of mitotic sister chromatid separation (GO:1901970)2.23758270
131regulation of cholesterol homeostasis (GO:2000188)2.22987390
132IMP biosynthetic process (GO:0006188)2.22728398
133positive regulation of chromosome segregation (GO:0051984)2.22600648
134negative regulation of cell size (GO:0045792)2.22360082
135mitotic sister chromatid segregation (GO:0000070)2.22214432
136endodermal cell differentiation (GO:0035987)2.21746770
137double-strand break repair via nonhomologous end joining (GO:0006303)2.20469938
138non-recombinational repair (GO:0000726)2.20469938
139nucleoside salvage (GO:0043174)2.20331886
140pre-miRNA processing (GO:0031054)2.19808937
141nuclear envelope organization (GO:0006998)2.18164696
142protein targeting to ER (GO:0045047)2.17707374
143establishment of apical/basal cell polarity (GO:0035089)2.17595378
144protein export from nucleus (GO:0006611)2.17447711
145establishment of chromosome localization (GO:0051303)2.17068286
146regulation of RNA export from nucleus (GO:0046831)2.17015864
147hemidesmosome assembly (GO:0031581)2.16999108
148negative regulation of fibrinolysis (GO:0051918)2.14865018
149pyrimidine-containing compound salvage (GO:0008655)2.14631321
150pyrimidine nucleoside salvage (GO:0043097)2.14631321
151mesodermal cell differentiation (GO:0048333)2.13695550
152nucleotide salvage (GO:0043173)2.13037827
153DNA unwinding involved in DNA replication (GO:0006268)2.13005919
154folic acid-containing compound metabolic process (GO:0006760)2.12350635
155retina vasculature morphogenesis in camera-type eye (GO:0061299)2.11668362
156RNA-dependent DNA replication (GO:0006278)2.10916370
157regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.10645454
158cytoskeleton-dependent cytokinesis (GO:0061640)2.09989854
159telomere maintenance via telomerase (GO:0007004)2.09910881
160NLS-bearing protein import into nucleus (GO:0006607)2.09433957
161midgut development (GO:0007494)2.09382687
162positive regulation of transforming growth factor beta production (GO:0071636)2.06820796
163keratinocyte development (GO:0003334)2.05677232
164DNA duplex unwinding (GO:0032508)2.05516030
165spindle assembly involved in mitosis (GO:0090307)2.04793124
166regulation of sister chromatid cohesion (GO:0007063)2.04534853
167mitotic spindle organization (GO:0007052)2.03952153
168regulation of establishment of planar polarity (GO:0090175)2.03809378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.78445302
2SALL1_21062744_ChIP-ChIP_HESCs_Human3.30660821
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.09354453
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.08968565
5KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.06730233
6WT1_19549856_ChIP-ChIP_CCG9911_Human2.74602613
7E2F7_22180533_ChIP-Seq_HELA_Human2.68407688
8SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.64502988
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.62948188
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.57907737
11PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.52431488
12ELK1_19687146_ChIP-ChIP_HELA_Human2.35021539
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.33628177
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.33294790
15TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.30450401
16RXR_22158963_ChIP-Seq_LIVER_Mouse2.28762746
17PPARA_22158963_ChIP-Seq_LIVER_Mouse2.24020506
18PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.17238359
19CLOCK_20551151_ChIP-Seq_293T_Human2.14652763
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.06462005
21MYC_22102868_ChIP-Seq_BL_Human2.06230226
22PADI4_21655091_ChIP-ChIP_MCF-7_Human2.03272297
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.99727291
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.92169678
25POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.78708283
26FUS_26573619_Chip-Seq_HEK293_Human1.72754848
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.71983331
28MYC_19079543_ChIP-ChIP_MESCs_Mouse1.69159964
29BRD4_25478319_ChIP-Seq_HGPS_Human1.67741701
30LXR_22158963_ChIP-Seq_LIVER_Mouse1.66816689
31GATA1_22025678_ChIP-Seq_K562_Human1.66055135
32HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.65331344
33TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64569714
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.55694189
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55523335
36TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55149831
37CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.54680138
38SALL4_18804426_ChIP-ChIP_XEN_Mouse1.53752854
39TFEB_21752829_ChIP-Seq_HELA_Human1.52914705
40CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.49483583
41MYC_19030024_ChIP-ChIP_MESCs_Mouse1.48580485
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48207085
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46942520
44SOX17_20123909_ChIP-Seq_XEN_Mouse1.46203878
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44772969
46ELK3_25401928_ChIP-Seq_HUVEC_Human1.44718491
47KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.44471908
48KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.44471908
49KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.44471908
50STAT3_1855785_ChIP-Seq_MESCs_Mouse1.44100823
51TCF3_18692474_ChIP-Seq_MEFs_Mouse1.43484454
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.43417784
53E2F1_21310950_ChIP-Seq_MCF-7_Human1.43042838
54ATF3_27146783_Chip-Seq_COLON_Human1.42455212
55CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.42202077
56TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.41479393
57MYC_18358816_ChIP-ChIP_MESCs_Mouse1.40262758
58FOXM1_23109430_ChIP-Seq_U2OS_Human1.39524561
59RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.39359263
60DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.38897065
61NELFA_20434984_ChIP-Seq_ESCs_Mouse1.38698621
62TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.38664577
63KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38431777
64ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.37823532
65SOX2_27498859_Chip-Seq_STOMACH_Mouse1.36441254
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.34569907
67* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.34492487
68CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.34363358
69FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.34108822
70ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33116193
71HIF1A_21447827_ChIP-Seq_MCF-7_Human1.32819187
72PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32674467
73SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.32251087
74SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.32251087
75SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.30759670
76* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.30265842
77SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.29883899
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29126657
79XRN2_22483619_ChIP-Seq_HELA_Human1.28604788
80ESR1_21235772_ChIP-Seq_MCF-7_Human1.28131866
81* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.26144326
82RACK7_27058665_Chip-Seq_MCF-7_Human1.25650843
83RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.25441748
84VDR_21846776_ChIP-Seq_THP-1_Human1.25103238
85EWS_26573619_Chip-Seq_HEK293_Human1.25093146
86NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24739371
87FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.24713260
88GABP_19822575_ChIP-Seq_HepG2_Human1.24077203
89CIITA_25753668_ChIP-Seq_RAJI_Human1.23499357
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23119951
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23053762
92NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.21999911
93FOXM1_26456572_ChIP-Seq_MCF-7_Human1.18965682
94CHD1_26751641_Chip-Seq_LNCaP_Human1.18364309
95TCF7_22412390_ChIP-Seq_EML_Mouse1.17387869
96TP63_19390658_ChIP-ChIP_HaCaT_Human1.17262506
97PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.17100309
98CJUN_26792858_Chip-Seq_BT549_Human1.16848751
99NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.16771594
100CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.16671800
101NANOG_16153702_ChIP-ChIP_HESCs_Human1.16374665
102NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.15309292
103AR_21909140_ChIP-Seq_LNCAP_Human1.14960424
104CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.14565773
105HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.14005068
106NCOR1_26117541_ChIP-Seq_K562_Human1.13892758
107KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.13864545
108NANOG_21062744_ChIP-ChIP_HESCs_Human1.13850855
109MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13436350
110ETS1_20019798_ChIP-Seq_JURKAT_Human1.11415801
111NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.11316335
112TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10917251
113TCF4_18268006_ChIP-ChIP_LS174T_Human1.10500353
114TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09809255
115LXR_22292898_ChIP-Seq_THP-1_Human1.08929568
116ZNF263_19887448_ChIP-Seq_K562_Human1.07417805
117GATA6_25053715_ChIP-Seq_YYC3_Human1.07187123
118ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06937573
119CREB1_15753290_ChIP-ChIP_HEK293T_Human1.06596228
120GABP_17652178_ChIP-ChIP_JURKAT_Human1.06258518
121FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.05378690
122TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04543612
123SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04401438
124SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.04147638
125PIAS1_25552417_ChIP-Seq_VCAP_Human1.03626313
126P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03350699
127EST1_17652178_ChIP-ChIP_JURKAT_Human1.02750670
128FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.02191820
129DCP1A_22483619_ChIP-Seq_HELA_Human1.00837505
130KDM5A_27292631_Chip-Seq_BREAST_Human1.00575776
131TP53_18474530_ChIP-ChIP_U2OS_Human1.00219090
132AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00111635
133NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.99061672
134NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.98916998
135NRF2_20460467_ChIP-Seq_MEFs_Mouse0.98916998
136GATA4_21415370_ChIP-Seq_HL-1_Mouse0.98029747
137FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.97551282
138ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.97372066
139HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97062896
140EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96698920
141FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.96662559
142FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.96070289
143CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95182338
144HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.93795846
145STAT6_21828071_ChIP-Seq_BEAS2B_Human0.93444960
146KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93410244
147NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.93014232
148POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.92547793
149ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.92444284
150TBX3_20139965_ChIP-Seq_ESCs_Mouse0.92234891
151JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.91892569
152TBX3_20139965_ChIP-Seq_MESCs_Mouse0.90491282
153ELF5_23300383_ChIP-Seq_T47D_Human0.90048165
154ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89744634
155* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.88428720
156FOXO3_23340844_ChIP-Seq_DLD1_Human0.88004709
157PCGF2_27294783_Chip-Seq_ESCs_Mouse0.85044286

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.48925226
2MP0002139_abnormal_hepatobiliary_system3.31017492
3MP0003941_abnormal_skin_development3.15306887
4MP0002877_abnormal_melanocyte_morpholog3.11976869
5MP0003705_abnormal_hypodermis_morpholog3.05930491
6MP0003283_abnormal_digestive_organ2.73542755
7MP0005275_abnormal_skin_tensile2.40979725
8MP0009697_abnormal_copulation2.22000779
9MP0003890_abnormal_embryonic-extraembry2.13029067
10MP0010352_gastrointestinal_tract_polyps2.07634182
11MP0006054_spinal_hemorrhage2.07574042
12MP0005220_abnormal_exocrine_pancreas2.05477022
13MP0005503_abnormal_tendon_morphology1.99549826
14MP0003566_abnormal_cell_adhesion1.95739968
15MP0003300_gastrointestinal_ulcer1.82468614
16MP0008932_abnormal_embryonic_tissue1.80017927
17MP0003252_abnormal_bile_duct1.78320354
18MP0003806_abnormal_nucleotide_metabolis1.77901546
19MP0005365_abnormal_bile_salt1.77591349
20MP0008057_abnormal_DNA_replication1.76767072
21MP0004264_abnormal_extraembryonic_tissu1.76500796
22MP0003950_abnormal_plasma_membrane1.76294619
23MP0002138_abnormal_hepatobiliary_system1.75967139
24MP0003111_abnormal_nucleus_morphology1.61093041
25MP0005076_abnormal_cell_differentiation1.59545585
26MP0003718_maternal_effect1.59130133
27MP0003195_calcinosis1.58720502
28MP0001944_abnormal_pancreas_morphology1.56134004
29MP0003937_abnormal_limbs/digits/tail_de1.51625082
30MP0005085_abnormal_gallbladder_physiolo1.49108715
31MP0001666_abnormal_nutrient_absorption1.48959593
32MP0004272_abnormal_basement_membrane1.48699369
33MP0002796_impaired_skin_barrier1.46992009
34MP0003279_aneurysm1.46958635
35MP0009840_abnormal_foam_cell1.45906801
36MP0002896_abnormal_bone_mineralization1.40868245
37MP0003385_abnormal_body_wall1.39430987
38MP0004233_abnormal_muscle_weight1.37283061
39MP0003077_abnormal_cell_cycle1.35043103
40MP0005623_abnormal_meninges_morphology1.33227477
41MP0010678_abnormal_skin_adnexa1.32961156
42MP0005023_abnormal_wound_healing1.31292162
43MP0003693_abnormal_embryo_hatching1.30232067
44MP0010094_abnormal_chromosome_stability1.29979639
45MP0005257_abnormal_intraocular_pressure1.29472642
46MP0003122_maternal_imprinting1.27954769
47MP0002693_abnormal_pancreas_physiology1.25880116
48MP0002233_abnormal_nose_morphology1.25216307
49MP0010030_abnormal_orbit_morphology1.25141020
50MP0001299_abnormal_eye_distance/1.23118922
51MP0005508_abnormal_skeleton_morphology1.21561195
52MP0000537_abnormal_urethra_morphology1.20478209
53MP0000678_abnormal_parathyroid_gland1.20429773
54MP0003935_abnormal_craniofacial_develop1.19059831
55MP0003755_abnormal_palate_morphology1.19030930
56MP0000762_abnormal_tongue_morphology1.18574344
57MP0005408_hypopigmentation1.16071781
58MP0000013_abnormal_adipose_tissue1.13629552
59MP0005083_abnormal_biliary_tract1.12201141
60MP0000432_abnormal_head_morphology1.11478653
61MP0003868_abnormal_feces_composition1.11385369
62MP0000003_abnormal_adipose_tissue1.10995331
63MP0000647_abnormal_sebaceous_gland1.09680338
64MP0010307_abnormal_tumor_latency1.09420623
65MP0002060_abnormal_skin_morphology1.08701954
66MP0005501_abnormal_skin_physiology1.08354530
67MP0003123_paternal_imprinting1.07296591
68MP0010234_abnormal_vibrissa_follicle1.06986542
69MP0002697_abnormal_eye_size1.06792862
70MP0000350_abnormal_cell_proliferation1.06068579
71MP0008058_abnormal_DNA_repair1.05073697
72MP0000462_abnormal_digestive_system1.05053333
73MP0001286_abnormal_eye_development1.04921862
74MP0004782_abnormal_surfactant_physiolog1.03866297
75MP0009053_abnormal_anal_canal1.03707782
76MP0005187_abnormal_penis_morphology1.02411860
77MP0008007_abnormal_cellular_replicative1.01962733
78MP0001661_extended_life_span1.01209940
79MP0005171_absent_coat_pigmentation1.00411812
80MP0005197_abnormal_uvea_morphology1.00365037
81MP0000428_abnormal_craniofacial_morphol0.99757767
82MP0002009_preneoplasia0.99137690
83MP0003119_abnormal_digestive_system0.99077339
84MP0004185_abnormal_adipocyte_glucose0.98550860
85MP0005360_urolithiasis0.98227072
86MP0004957_abnormal_blastocyst_morpholog0.97323327
87MP0004197_abnormal_fetal_growth/weight/0.96104612
88MP0009643_abnormal_urine_homeostasis0.95854968
89MP0003942_abnormal_urinary_system0.95312379
90MP0002928_abnormal_bile_duct0.94981579
91MP0009250_abnormal_appendicular_skeleto0.94649311
92MP0009384_cardiac_valve_regurgitation0.94586344
93MP0005375_adipose_tissue_phenotype0.93561947
94MP0002006_tumorigenesis0.92149506
95MP0001243_abnormal_dermal_layer0.91527959
96MP0000534_abnormal_ureter_morphology0.91357505
97MP0000163_abnormal_cartilage_morphology0.90550604
98MP0003091_abnormal_cell_migration0.89288105
99MP0001216_abnormal_epidermal_layer0.88720115
100MP0000613_abnormal_salivary_gland0.88649511
101MP0009780_abnormal_chondrocyte_physiolo0.88233722
102MP0004134_abnormal_chest_morphology0.87055080
103MP0001293_anophthalmia0.87005269
104MP0000383_abnormal_hair_follicle0.86449074
105MP0002177_abnormal_outer_ear0.84971478
106MP0000566_synostosis0.84925416
107MP0010368_abnormal_lymphatic_system0.84910320
108MP0002088_abnormal_embryonic_growth/wei0.84503473
109MP0000427_abnormal_hair_cycle0.83755994
110MP0003984_embryonic_growth_retardation0.83653116
111MP0000627_abnormal_mammary_gland0.82442452
112MP0005058_abnormal_lysosome_morphology0.82334498
113MP0003567_abnormal_fetal_cardiomyocyte0.82192601
114MP0009672_abnormal_birth_weight0.81737382
115MP0003115_abnormal_respiratory_system0.81284117
116MP0005666_abnormal_adipose_tissue0.80634970
117MP0002098_abnormal_vibrissa_morphology0.80372421
118MP0002086_abnormal_extraembryonic_tissu0.78896517
119MP0000516_abnormal_urinary_system0.78771104
120MP0005367_renal/urinary_system_phenotyp0.78771104
121MP0002837_dystrophic_cardiac_calcinosis0.78164958
122MP0001849_ear_inflammation0.77930675
123MP0002108_abnormal_muscle_morphology0.77803843
124MP0000733_abnormal_muscle_development0.77709221
125MP0002078_abnormal_glucose_homeostasis0.77704286
126MP0008961_abnormal_basal_metabolism0.77609946
127MP0001672_abnormal_embryogenesis/_devel0.77232898
128MP0005380_embryogenesis_phenotype0.77232898
129MP0000598_abnormal_liver_morphology0.77200093
130MP0000750_abnormal_muscle_regeneration0.77138590
131MP0002111_abnormal_tail_morphology0.76572785
132MP0000609_abnormal_liver_physiology0.76306509
133MP0005319_abnormal_enzyme/_coenzyme0.74786748
134MP0001730_embryonic_growth_arrest0.74653810
135MP0002932_abnormal_joint_morphology0.74341881
136MP0002269_muscular_atrophy0.74225010
137MP0002084_abnormal_developmental_patter0.73416756
138MP0001270_distended_abdomen0.72917357
139MP0002115_abnormal_skeleton_extremities0.72806925
140MP0009703_decreased_birth_body0.72137672
141MP0010329_abnormal_lipoprotein_level0.72093357
142MP0001697_abnormal_embryo_size0.71514254
143MP0001958_emphysema0.71506488
144MP0005390_skeleton_phenotype0.71469720
145MP0003959_abnormal_lean_body0.71314938
146MP0002938_white_spotting0.70802348
147MP0003795_abnormal_bone_structure0.70011725
148MP0002080_prenatal_lethality0.68913860
149MP0001915_intracranial_hemorrhage0.68739746
150MP0002085_abnormal_embryonic_tissue0.67990310
151MP0002168_other_aberrant_phenotype0.67499950

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.11462460
2Premature rupture of membranes (HP:0001788)4.27220393
3Hypoglycemic coma (HP:0001325)4.17244845
4Hyperinsulinemic hypoglycemia (HP:0000825)4.08816662
5Hypoglycemic seizures (HP:0002173)3.54636383
6Hyperglycemia (HP:0003074)3.01830042
7Abnormality of monocarboxylic acid metabolism (HP:0010996)3.01416407
8Arterial tortuosity (HP:0005116)3.00782610
9Cervical subluxation (HP:0003308)2.97366121
10Cerebral aneurysm (HP:0004944)2.93112237
11Intrahepatic cholestasis (HP:0001406)2.92695160
12Vascular tortuosity (HP:0004948)2.85264996
13Abnormality of the intrinsic pathway (HP:0010989)2.83476266
14Abnormality of endocrine pancreas physiology (HP:0012093)2.82394705
15Abnormality of the pancreatic islet cells (HP:0006476)2.82394705
16Symptomatic seizures (HP:0011145)2.76239137
17Ketoacidosis (HP:0001993)2.73118908
18Papillary thyroid carcinoma (HP:0002895)2.67093606
19Pancreatic islet-cell hyperplasia (HP:0004510)2.62448329
20Ankle contracture (HP:0006466)2.59065651
21Late onset (HP:0003584)2.55524441
22Abnormality of dentin (HP:0010299)2.51680191
23Follicular hyperkeratosis (HP:0007502)2.50197090
24Ankyloglossia (HP:0010296)2.47121583
25Peritonitis (HP:0002586)2.45599565
26Insulin-resistant diabetes mellitus (HP:0000831)2.42642218
27Atrophic scars (HP:0001075)2.38334277
28Soft skin (HP:0000977)2.38094703
29Asymmetry of the thorax (HP:0001555)2.35638176
30Overlapping toe (HP:0001845)2.31588201
31Curly hair (HP:0002212)2.30490582
32Cortical dysplasia (HP:0002539)2.29802852
33Blue sclerae (HP:0000592)2.29610360
34Mildly elevated creatine phosphokinase (HP:0008180)2.26053540
35Aortic aneurysm (HP:0004942)2.25008367
36Thoracolumbar scoliosis (HP:0002944)2.23954301
37Genu recurvatum (HP:0002816)2.23950125
38Abnormal pancreas size (HP:0012094)2.23072422
39Mucopolysacchariduria (HP:0008155)2.22620776
40Urinary glycosaminoglycan excretion (HP:0003541)2.22620776
41Metaphyseal cupping (HP:0003021)2.21358280
42Aortic dissection (HP:0002647)2.21309007
43Short middle phalanx of the 5th finger (HP:0004220)2.19965820
44Shallow orbits (HP:0000586)2.19795733
45Insulin resistance (HP:0000855)2.19709871
46Abnormality of oral frenula (HP:0000190)2.19547452
47Ketosis (HP:0001946)2.16978900
48Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.16227210
49Thin bony cortex (HP:0002753)2.16015511
50Generalized amyotrophy (HP:0003700)2.15942844
51Hypoplastic ischia (HP:0003175)2.15924939
52Aneurysm (HP:0002617)2.13786211
53Abnormality of the common coagulation pathway (HP:0010990)2.12842640
54Bladder diverticulum (HP:0000015)2.11687565
55Selective tooth agenesis (HP:0001592)2.11560177
56Mitral valve prolapse (HP:0001634)2.11487868
57Beaking of vertebral bodies (HP:0004568)2.09319807
58Deep philtrum (HP:0002002)2.08343151
59Abnormality of aromatic amino acid family metabolism (HP:0004338)2.07377245
60Thyroid carcinoma (HP:0002890)2.05828257
61Hand muscle atrophy (HP:0009130)2.05590764
62Abnormality of the acetabulum (HP:0003170)2.05231392
63Exostoses (HP:0100777)2.03498069
64Vertebral compression fractures (HP:0002953)2.02888026
65Vertebral arch anomaly (HP:0008438)2.01862839
66Missing ribs (HP:0000921)2.01210131
67Abnormal cartilage morphology (HP:0002763)2.00553101
68Biconcave vertebral bodies (HP:0004586)1.99058826
69Wide cranial sutures (HP:0010537)1.98325841
70Abnormality of the distal phalanges of the toes (HP:0010182)1.97837546
71Septate vagina (HP:0001153)1.97614470
72Platyspondyly (HP:0000926)1.97035257
73Abnormality of polysaccharide metabolism (HP:0011012)1.96336877
74Abnormality of glycosaminoglycan metabolism (HP:0004371)1.96336877
75Abnormality of mucopolysaccharide metabolism (HP:0011020)1.96336877
76Large for gestational age (HP:0001520)1.94194854
77Abnormality of the ischium (HP:0003174)1.93860556
78Fragile skin (HP:0001030)1.93033588
79Bifid tongue (HP:0010297)1.92645860
80Type 1 muscle fiber predominance (HP:0003803)1.91551611
81Dilatation of the ascending aorta (HP:0005111)1.91321021
82Wormian bones (HP:0002645)1.90598486
83Increased connective tissue (HP:0009025)1.89352908
84Increased nuchal translucency (HP:0010880)1.88186117
85Tetraparesis (HP:0002273)1.86465977
86Absent eyebrow (HP:0002223)1.85515961
87Spinal rigidity (HP:0003306)1.85304461
88Absent eyelashes (HP:0000561)1.83398374
89Subacute progressive viral hepatitis (HP:0006572)1.81739391
90Multiple enchondromatosis (HP:0005701)1.80379213
91Back pain (HP:0003418)1.79296853
92Degeneration of anterior horn cells (HP:0002398)1.79295094
93Abnormality of the anterior horn cell (HP:0006802)1.79295094
94Xanthomatosis (HP:0000991)1.79119345
95Protuberant abdomen (HP:0001538)1.78967963
96Vertebral clefting (HP:0008428)1.78636970
97Microglossia (HP:0000171)1.78230357
98Abdominal distention (HP:0003270)1.75393403
99Orthostatic hypotension (HP:0001278)1.75344283
100Broad metatarsal (HP:0001783)1.73952033
101Hypoplastic labia majora (HP:0000059)1.73802137
102Abnormal delivery (HP:0001787)1.73069684
103Neonatal short-limb short stature (HP:0008921)1.72886011
104Capillary hemangiomas (HP:0005306)1.72642884
105Renal duplication (HP:0000075)1.72460539
106Dysostosis multiplex (HP:0000943)1.71392656
107Nonimmune hydrops fetalis (HP:0001790)1.70559229
108Skin nodule (HP:0200036)1.70266927
109Delayed closure of the anterior fontanelle (HP:0001476)1.70258422
110Deviation of the thumb (HP:0009603)1.70140228
111Severe short stature (HP:0003510)1.69618123
112Termporal pattern (HP:0011008)1.69588344
113Insidious onset (HP:0003587)1.69588344
114Hyperextensible skin (HP:0000974)1.69099513
115Trismus (HP:0000211)1.68992045
116Right ventricular cardiomyopathy (HP:0011663)1.68650283
117Decreased subcutaneous fat (HP:0001002)1.68432281
118Ulnar bowing (HP:0003031)1.68271356
119Chromsome breakage (HP:0040012)1.67713226
120Deep venous thrombosis (HP:0002625)1.67638332
121Embryonal renal neoplasm (HP:0011794)1.66970100
122Disproportionate tall stature (HP:0001519)1.66953395
123Abnormality of alkaline phosphatase activity (HP:0004379)1.66548911
124Abnormal enzyme/coenzyme activity (HP:0012379)1.65159359
125Proximal tubulopathy (HP:0000114)1.64881516
126Distal upper limb amyotrophy (HP:0007149)1.64386756
127Upper limb amyotrophy (HP:0009129)1.64386756
128Pterygium (HP:0001059)1.64299648
129Ectopia lentis (HP:0001083)1.64171725
130Joint laxity (HP:0001388)1.62218894
131Breech presentation (HP:0001623)1.62195923
132Generalized aminoaciduria (HP:0002909)1.61777973
133Abnormality of the labia minora (HP:0012880)1.61758319
134Wide nose (HP:0000445)1.60363377
135Joint stiffness (HP:0001387)1.60050255
136Cutaneous melanoma (HP:0012056)1.58907358
137Sparse lateral eyebrow (HP:0005338)1.58386918
138Bowel diverticulosis (HP:0005222)1.58235883
139Chromosomal breakage induced by crosslinking agents (HP:0003221)1.58189672
140Hepatoblastoma (HP:0002884)1.57886911
141Nephroblastoma (Wilms tumor) (HP:0002667)1.57629587
142Macroorchidism (HP:0000053)1.57369251
143Overgrowth (HP:0001548)1.56542069
144Turricephaly (HP:0000262)1.56453153
145Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.56324522
146Redundant skin (HP:0001582)1.54144663
147Aplasia/Hypoplasia of the scapulae (HP:0006713)1.54043642
148Hypoplastic scapulae (HP:0000882)1.54043642
149Cystic hygroma (HP:0000476)1.53676198
150Abnormality of the labia majora (HP:0012881)1.52794109
151Broad palm (HP:0001169)1.50527968
152Limb-girdle muscle weakness (HP:0003325)1.50219459
153Coronal craniosynostosis (HP:0004440)1.50012928
154Short middle phalanx of finger (HP:0005819)1.49414867
155Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.49105533
156Vertebral hypoplasia (HP:0008417)1.49105533
157Spinal cord lesions (HP:0100561)1.48878844
158Syringomyelia (HP:0003396)1.48878844
159Lip pit (HP:0100267)1.48421353
160Long palpebral fissure (HP:0000637)1.48420992
161Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.47870858
162Proximal placement of thumb (HP:0009623)1.47700376
163Abnormal foot bone ossification (HP:0010675)1.45899314
164Abnormality of the musculature of the pelvis (HP:0001469)1.44415163
165Abnormality of the hip-girdle musculature (HP:0001445)1.44415163
166Heterotopia (HP:0002282)1.44244112
167Flat acetabular roof (HP:0003180)1.43654279
168Anal stenosis (HP:0002025)1.43359324
169Osteolytic defects of the phalanges of the hand (HP:0009771)1.43296569
170Osteolytic defects of the hand bones (HP:0009699)1.43296569
171Entropion (HP:0000621)1.40656333
172Bladder carcinoma (HP:0002862)1.40560063
173Bladder neoplasm (HP:0009725)1.40560063
174Neoplasm of the oral cavity (HP:0100649)1.40502114
175Abnormal hair whorl (HP:0010721)1.40206532
176Pectus carinatum (HP:0000768)1.39184249
177Alopecia of scalp (HP:0002293)1.39135716
178Pes planus (HP:0001763)1.39068203

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.58971019
2TRIB33.54567956
3PKN23.13716916
4STK32.85171913
5PASK2.81019783
6SRPK12.64661258
7INSRR2.43035374
8FLT32.37996405
9BCR2.37286224
10EEF2K2.19842799
11TAOK32.18810484
12SIK12.11325980
13PTK62.10405135
14TSSK62.07764847
15PDGFRA2.05033130
16PBK2.01370645
17LATS11.97985490
18BCKDK1.88978871
19MAP3K101.85739210
20TRIM281.85582919
21STK241.84296510
22DDR21.81435595
23BRD41.76365112
24MAPKAPK31.69777196
25ERBB41.64760245
26EPHA21.56263170
27EPHA31.46285309
28RIPK11.41577956
29ERBB31.40941992
30PLK31.35983915
31CDK121.35558885
32CLK11.34318628
33TAF11.33451577
34LRRK21.31282306
35MET1.29945498
36SCYL21.27419927
37MTOR1.27181877
38RPS6KB21.25806910
39TTN1.23368050
40MKNK11.22436583
41STK101.18520173
42PTK21.17477876
43PIM21.15326292
44FGFR41.13729260
45YES11.13564042
46HIPK21.13103090
47PLK41.12351125
48LMTK21.12045475
49LATS21.11957951
50BRSK21.11684572
51FRK1.11539715
52TNIK1.10611986
53PNCK1.10136411
54MST41.08304388
55TTK1.06320517
56CAMK1G1.05449573
57MKNK21.02986216
58MAPK151.02519263
59MAP3K30.98618729
60STK390.97727175
61PAK40.96877345
62CDC70.96200977
63CDK60.96063007
64MATK0.95564599
65KSR10.95348034
66RPS6KA40.94566632
67EIF2AK30.92541980
68PIK3CG0.92474509
69PAK20.89771450
70PLK10.88716338
71DYRK1B0.86618543
72BRSK10.86535061
73PDK20.85068334
74MAP3K40.84545397
75MAP3K80.83363190
76TESK10.82693597
77MAP2K20.82523874
78TGFBR10.82217186
79NTRK10.80714747
80MYLK0.78131045
81MAP2K30.75892773
82CDK40.73635238
83NEK20.73602888
84TGFBR20.73029918
85ACVR1B0.72345996
86NLK0.71644848
87CDK70.71288673
88DYRK30.71176982
89ALK0.69217100
90CHEK10.68869652
91WNK30.68710953
92IRAK30.68006569
93EPHB10.67949780
94ATM0.67732796
95FER0.66867157
96EIF2AK20.66766764
97NEK90.65061328
98LIMK10.64066717
99MAP3K120.61107309
100ICK0.60148895
101NME20.58528383
102EPHB20.57825240
103KSR20.57662825
104FGFR10.56433951
105AKT30.55462753
106KDR0.54208525
107RAF10.53338952
108CHEK20.52783425
109CSNK1G10.52484428
110EIF2AK10.51988234
111PAK30.51711077
112TRPM70.51137031
113WNK10.50808317
114CDK80.50804280
115DMPK0.50647021
116MELK0.50186030
117MAP3K110.50023330
118CDC42BPA0.49763409
119ILK0.47378983
120STK38L0.46859782
121MAP3K10.45911871
122MAPK110.45589113
123JAK30.45467879
124SIK30.45217683
125PLK20.44950451
126CSNK1E0.44243910
127MST1R0.44084559
128PRKCE0.43514949
129NUAK10.42957524
130PRKCI0.42832483
131CAMK1D0.42731892
132CDK10.41435089
133MAP4K20.41406369
134TBK10.41381091
135ZAP700.41242747
136MAP3K20.39752665
137FGFR30.39723299
138CHUK0.39618830
139PRKG20.38924306
140BUB10.38117790
141WEE10.37967034
142BMX0.37440815
143PDGFRB0.36394591
144GSK3A0.36096953
145NEK10.33850412
146AURKB0.33389305
147MAPK10.32372442
148MAPKAPK20.32087673
149ATR0.31057198

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049505.04878701
2Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.20690636
3Protein export_Homo sapiens_hsa030603.13417666
4Selenocompound metabolism_Homo sapiens_hsa004502.68045741
5One carbon pool by folate_Homo sapiens_hsa006702.27802289
6Steroid biosynthesis_Homo sapiens_hsa001002.20167513
7Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.09660360
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.05384489
9Basal transcription factors_Homo sapiens_hsa030221.97252657
10Non-homologous end-joining_Homo sapiens_hsa034501.89839706
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.87922105
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80832905
13Folate biosynthesis_Homo sapiens_hsa007901.79401694
14N-Glycan biosynthesis_Homo sapiens_hsa005101.69030286
15Protein digestion and absorption_Homo sapiens_hsa049741.63470285
16Sulfur metabolism_Homo sapiens_hsa009201.61873807
17Fat digestion and absorption_Homo sapiens_hsa049751.60279690
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57973415
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.56731010
20Tryptophan metabolism_Homo sapiens_hsa003801.56193414
21Galactose metabolism_Homo sapiens_hsa000521.55553237
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.49403777
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.47006114
24mRNA surveillance pathway_Homo sapiens_hsa030151.44818917
25Fatty acid degradation_Homo sapiens_hsa000711.32537057
26Nucleotide excision repair_Homo sapiens_hsa034201.32328817
27Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.32200746
28Lysine degradation_Homo sapiens_hsa003101.29199304
29Starch and sucrose metabolism_Homo sapiens_hsa005001.27929367
30ECM-receptor interaction_Homo sapiens_hsa045121.27856260
31Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.23703953
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23630705
33Circadian rhythm_Homo sapiens_hsa047101.23459686
34Fatty acid elongation_Homo sapiens_hsa000621.18762111
35Other glycan degradation_Homo sapiens_hsa005111.17466538
36Glycosaminoglycan degradation_Homo sapiens_hsa005311.16247167
37Bladder cancer_Homo sapiens_hsa052191.13003770
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.11016428
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10114245
40Drug metabolism - other enzymes_Homo sapiens_hsa009831.09968228
41Insulin resistance_Homo sapiens_hsa049311.06954635
42Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.03757874
43Proteasome_Homo sapiens_hsa030501.02515322
44RNA degradation_Homo sapiens_hsa030181.02055865
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.98105374
46Focal adhesion_Homo sapiens_hsa045100.95239311
47Hippo signaling pathway_Homo sapiens_hsa043900.95183096
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.94936798
49Tight junction_Homo sapiens_hsa045300.94300299
50Vibrio cholerae infection_Homo sapiens_hsa051100.91632436
51Small cell lung cancer_Homo sapiens_hsa052220.90166147
52Pyruvate metabolism_Homo sapiens_hsa006200.90083808
53Lysosome_Homo sapiens_hsa041420.90008733
54RNA transport_Homo sapiens_hsa030130.89722883
55Complement and coagulation cascades_Homo sapiens_hsa046100.86659713
56Renin-angiotensin system_Homo sapiens_hsa046140.86159990
57Biosynthesis of amino acids_Homo sapiens_hsa012300.85980654
58Vitamin digestion and absorption_Homo sapiens_hsa049770.85948573
59Fructose and mannose metabolism_Homo sapiens_hsa000510.84363295
60Adherens junction_Homo sapiens_hsa045200.84027939
61Thyroid cancer_Homo sapiens_hsa052160.83992284
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.83694545
63Basal cell carcinoma_Homo sapiens_hsa052170.81000344
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.80725122
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80678913
66Chronic myeloid leukemia_Homo sapiens_hsa052200.79045772
67ABC transporters_Homo sapiens_hsa020100.78147615
68Fanconi anemia pathway_Homo sapiens_hsa034600.77414162
69Proteoglycans in cancer_Homo sapiens_hsa052050.76390859
70Legionellosis_Homo sapiens_hsa051340.76267452
71Sphingolipid metabolism_Homo sapiens_hsa006000.76003510
72p53 signaling pathway_Homo sapiens_hsa041150.74591476
73Carbon metabolism_Homo sapiens_hsa012000.74334106
74Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72584160
75Endometrial cancer_Homo sapiens_hsa052130.71234323
76Ribosome_Homo sapiens_hsa030100.70936900
77Arginine and proline metabolism_Homo sapiens_hsa003300.70927815
78Cell cycle_Homo sapiens_hsa041100.70718760
79Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70337959
80Arginine biosynthesis_Homo sapiens_hsa002200.69710738
81Fatty acid metabolism_Homo sapiens_hsa012120.69093454
82Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65854818
83Amoebiasis_Homo sapiens_hsa051460.64939343
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.63846446
85Nitrogen metabolism_Homo sapiens_hsa009100.63739930
86TGF-beta signaling pathway_Homo sapiens_hsa043500.62731866
87Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62168917
88Sulfur relay system_Homo sapiens_hsa041220.61514209
89DNA replication_Homo sapiens_hsa030300.61363404
90Renal cell carcinoma_Homo sapiens_hsa052110.61254652
91Mismatch repair_Homo sapiens_hsa034300.61006453
92PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60505814
93Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60197813
94AMPK signaling pathway_Homo sapiens_hsa041520.57829190
95Melanoma_Homo sapiens_hsa052180.57444249
96Oocyte meiosis_Homo sapiens_hsa041140.56677987
97Wnt signaling pathway_Homo sapiens_hsa043100.56084769
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55535529
99Acute myeloid leukemia_Homo sapiens_hsa052210.55530857
100MicroRNAs in cancer_Homo sapiens_hsa052060.55223596
101Pancreatic cancer_Homo sapiens_hsa052120.54724003
102Colorectal cancer_Homo sapiens_hsa052100.54666638
103mTOR signaling pathway_Homo sapiens_hsa041500.54327184
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54259163
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53971654
106Phenylalanine metabolism_Homo sapiens_hsa003600.53796827
107Thyroid hormone synthesis_Homo sapiens_hsa049180.53766218
108PPAR signaling pathway_Homo sapiens_hsa033200.52865390
109Insulin signaling pathway_Homo sapiens_hsa049100.52713512
110Hedgehog signaling pathway_Homo sapiens_hsa043400.52127987
111Prostate cancer_Homo sapiens_hsa052150.51738059
112Antigen processing and presentation_Homo sapiens_hsa046120.51536551
113Peroxisome_Homo sapiens_hsa041460.50046983
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49579725
115Histidine metabolism_Homo sapiens_hsa003400.49558644
116Glutathione metabolism_Homo sapiens_hsa004800.49436035
117Pathways in cancer_Homo sapiens_hsa052000.49381369
118Propanoate metabolism_Homo sapiens_hsa006400.48829832
119Viral carcinogenesis_Homo sapiens_hsa052030.48812372
120Glucagon signaling pathway_Homo sapiens_hsa049220.48730252
121Shigellosis_Homo sapiens_hsa051310.46815652
122Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46461644
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.45882891
124Caffeine metabolism_Homo sapiens_hsa002320.45564532
125Cyanoamino acid metabolism_Homo sapiens_hsa004600.45199960
126Pentose phosphate pathway_Homo sapiens_hsa000300.45070238
127RNA polymerase_Homo sapiens_hsa030200.43697134
128Pyrimidine metabolism_Homo sapiens_hsa002400.43159937
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42510158
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42354684
131AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.42302771
132Spliceosome_Homo sapiens_hsa030400.41974049
133Base excision repair_Homo sapiens_hsa034100.41389292
134Notch signaling pathway_Homo sapiens_hsa043300.41240088
135Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38903556
136Type II diabetes mellitus_Homo sapiens_hsa049300.37749941

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