PRRC2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)4.44987761
2DNA unwinding involved in DNA replication (GO:0006268)4.18911355
3COPI coating of Golgi vesicle (GO:0048205)4.02377552
4Golgi transport vesicle coating (GO:0048200)4.02377552
5peptidyl-lysine dimethylation (GO:0018027)4.00127562
6regulation of histone H3-K27 methylation (GO:0061085)3.92173495
7mitotic chromosome condensation (GO:0007076)3.85054942
8positive regulation of histone deacetylation (GO:0031065)3.81653405
9regulation of NFAT protein import into nucleus (GO:0051532)3.76662522
10glucocorticoid receptor signaling pathway (GO:0042921)3.75971383
11heterochromatin organization (GO:0070828)3.71078451
12regulation of mammary gland epithelial cell proliferation (GO:0033599)3.70401621
13cytoskeletal anchoring at plasma membrane (GO:0007016)3.70259584
14activation of Rac GTPase activity (GO:0032863)3.59638399
15cytoplasmic mRNA processing body assembly (GO:0033962)3.56442592
16NLS-bearing protein import into nucleus (GO:0006607)3.56382458
17negative regulation of cell size (GO:0045792)3.46735939
18intracellular estrogen receptor signaling pathway (GO:0030520)3.30200671
19regulation of early endosome to late endosome transport (GO:2000641)3.28325912
20retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.25548180
21maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.25508347
22protein retention in ER lumen (GO:0006621)3.24062699
23regulation of glucose import in response to insulin stimulus (GO:2001273)3.23876022
24RNA stabilization (GO:0043489)3.19892944
25mRNA stabilization (GO:0048255)3.19892944
26nuclear pore complex assembly (GO:0051292)3.18425838
273-UTR-mediated mRNA stabilization (GO:0070935)3.12675140
28regulation of translational fidelity (GO:0006450)3.11463511
29proline biosynthetic process (GO:0006561)3.11067926
30adherens junction assembly (GO:0034333)3.05303871
31regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.05283602
32insulin-like growth factor receptor signaling pathway (GO:0048009)3.03268265
33planar cell polarity pathway involved in neural tube closure (GO:0090179)3.02679755
34corticosteroid receptor signaling pathway (GO:0031958)3.02266072
35layer formation in cerebral cortex (GO:0021819)2.99587971
36regulation of translational termination (GO:0006449)2.99472805
37protein-DNA complex disassembly (GO:0032986)2.98825589
38nucleosome disassembly (GO:0006337)2.98825589
39positive regulation of RNA splicing (GO:0033120)2.97201395
40stress granule assembly (GO:0034063)2.94705871
41pore complex assembly (GO:0046931)2.92795201
42negative regulation of histone methylation (GO:0031061)2.92565546
43semaphorin-plexin signaling pathway (GO:0071526)2.91546002
44protein export from nucleus (GO:0006611)2.88302045
45gene silencing (GO:0016458)2.86749516
46establishment of apical/basal cell polarity (GO:0035089)2.84344725
47nuclear pore organization (GO:0006999)2.84240780
48hippo signaling (GO:0035329)2.83082159
49negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.82703106
50positive regulation of gene expression, epigenetic (GO:0045815)2.82640218
51regulation of RNA export from nucleus (GO:0046831)2.81977777
52embryonic process involved in female pregnancy (GO:0060136)2.80696826
53gene silencing by RNA (GO:0031047)2.79513419
54sodium ion export (GO:0071436)2.79138365
55regulation of hippo signaling (GO:0035330)2.78448163
56establishment of nucleus localization (GO:0040023)2.75663336
57embryonic foregut morphogenesis (GO:0048617)2.75480867
58polarized epithelial cell differentiation (GO:0030859)2.74121870
59mannose metabolic process (GO:0006013)2.73875028
60chromosome condensation (GO:0030261)2.73719863
61mitotic sister chromatid cohesion (GO:0007064)2.72122316
62basement membrane organization (GO:0071711)2.68694813
63cell-substrate adherens junction assembly (GO:0007045)2.67806774
64focal adhesion assembly (GO:0048041)2.67806774
65epithelial cell differentiation involved in prostate gland development (GO:0060742)2.66251411
66positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.66036251
67positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.65063876
68chromatin silencing (GO:0006342)2.64697146
69cell-cell junction maintenance (GO:0045217)2.63036057
70glial cell proliferation (GO:0014009)2.62239464
71positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.62051796
72convergent extension (GO:0060026)2.61151686
73regulation of chromatin binding (GO:0035561)2.60880101
74embryonic eye morphogenesis (GO:0048048)2.58094070
75stress fiber assembly (GO:0043149)2.56756839
76negative regulation of fatty acid transport (GO:2000192)2.56245999
77regulation of ARF GTPase activity (GO:0032312)2.55349869
78regulation of nucleobase-containing compound transport (GO:0032239)2.54744357
79plasma membrane repair (GO:0001778)2.52297021
80mitotic sister chromatid segregation (GO:0000070)2.52279605
81epithelial cell-cell adhesion (GO:0090136)2.52260093
82histone H3-K9 demethylation (GO:0033169)2.51829752
83cell-substrate junction assembly (GO:0007044)2.50082931
84neural tube development (GO:0021915)2.48167625
85spliceosomal tri-snRNP complex assembly (GO:0000244)2.46621380
86establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.46021336
87histone lysine demethylation (GO:0070076)2.45857338
88protein localization to microtubule (GO:0035372)2.45574223
89trophectodermal cell differentiation (GO:0001829)2.45410120
90apoptotic process involved in morphogenesis (GO:0060561)2.45379499
91positive regulation of protein deacetylation (GO:0090312)2.45313154
92embryonic camera-type eye morphogenesis (GO:0048596)2.44788647
93sister chromatid segregation (GO:0000819)2.44695572
94G1 DNA damage checkpoint (GO:0044783)2.43845976
95establishment or maintenance of monopolar cell polarity (GO:0061339)2.43734505
96establishment of monopolar cell polarity (GO:0061162)2.43734505
97negative regulation of mRNA metabolic process (GO:1903312)2.43691476
98positive regulation of DNA-dependent DNA replication (GO:2000105)2.42757778
99protein complex localization (GO:0031503)2.42309748
100receptor catabolic process (GO:0032801)2.41294472
101regulation of mitotic spindle organization (GO:0060236)2.41258943
102cellular protein complex localization (GO:0034629)2.41063818
103peptidyl-arginine omega-N-methylation (GO:0035247)2.40901320
104histone H4-K16 acetylation (GO:0043984)2.40329658
105protein localization to endosome (GO:0036010)2.40280295
106positive regulation of blood vessel endothelial cell migration (GO:0043536)2.39435023
107maternal placenta development (GO:0001893)2.39129228
108modulation by virus of host morphology or physiology (GO:0019048)2.38786978
109regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.36746586
110dosage compensation (GO:0007549)2.36402630
111DNA topological change (GO:0006265)2.36285938
112DNA duplex unwinding (GO:0032508)2.36094289
113regulation of mRNA stability (GO:0043488)2.35811789
114protein targeting to plasma membrane (GO:0072661)2.35432610
115negative regulation of myotube differentiation (GO:0010832)2.35371314
116positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.34136061
117synaptonemal complex assembly (GO:0007130)2.33895819
118gastrulation with mouth forming second (GO:0001702)2.33430283
119histone H4 deacetylation (GO:0070933)2.32796381
120snRNA metabolic process (GO:0016073)2.32638581
121activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.30998580
122negative regulation of gene expression, epigenetic (GO:0045814)2.29920717
123cortical actin cytoskeleton organization (GO:0030866)2.29837198
124heart morphogenesis (GO:0003007)2.28051671
125mitotic G1 DNA damage checkpoint (GO:0031571)2.27450067
126negative regulation of mRNA processing (GO:0050686)2.26730213
127positive regulation of SMAD protein import into nucleus (GO:0060391)2.25437136
128negative regulation of glial cell proliferation (GO:0060253)2.25272649
129regulation of clathrin-mediated endocytosis (GO:2000369)2.25091051
130negative regulation of catenin import into nucleus (GO:0035414)2.24982736
131positive regulation of nuclease activity (GO:0032075)2.24697673
132negative regulation of RNA splicing (GO:0033119)2.23726355
133chromatin assembly (GO:0031497)2.23596060
134negative regulation of organelle assembly (GO:1902116)2.23014028
135peptidyl-threonine phosphorylation (GO:0018107)2.22686946
136histone H3-K36 demethylation (GO:0070544)2.22242304
137paraxial mesoderm development (GO:0048339)2.21802421
138peptidyl-threonine modification (GO:0018210)2.21690636
139germ cell migration (GO:0008354)2.21353936
140anatomical structure regression (GO:0060033)2.20800575
141regulation of ARF protein signal transduction (GO:0032012)2.20728450
142negative regulation of nucleotide catabolic process (GO:0030812)2.20031774
143cellular response to epidermal growth factor stimulus (GO:0071364)2.19210907
144response to epidermal growth factor (GO:0070849)2.17578575
145activation of JUN kinase activity (GO:0007257)2.17069387
146regulation of RNA stability (GO:0043487)2.16989169
147protein heterotrimerization (GO:0070208)2.16975441
148negative regulation of erythrocyte differentiation (GO:0045647)2.16654112
149regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.16526331
150histone H3-K4 methylation (GO:0051568)2.16464165

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.73269948
2MYC_22102868_ChIP-Seq_BL_Human3.70801913
3STAT6_21828071_ChIP-Seq_BEAS2B_Human3.42304067
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.39171755
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.28503406
6EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.91142967
7KDM2B_26808549_Chip-Seq_DND41_Human2.88684884
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.71900353
9TCF7_22412390_ChIP-Seq_EML_Mouse2.69684195
10KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.53289248
11ZFP281_18757296_ChIP-ChIP_E14_Mouse2.52443939
12KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.50184202
13E2F7_22180533_ChIP-Seq_HELA_Human2.42935684
14ZFP281_27345836_Chip-Seq_ESCs_Mouse2.31230795
15VDR_21846776_ChIP-Seq_THP-1_Human2.29148122
16KDM2B_26808549_Chip-Seq_K562_Human2.14607100
17ELK3_25401928_ChIP-Seq_HUVEC_Human2.13658107
18KDM2B_26808549_Chip-Seq_JURKAT_Human2.09317530
19DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.08587222
20WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.06791132
21LXR_22292898_ChIP-Seq_THP-1_Human2.04507770
22ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.98348288
23ZNF263_19887448_ChIP-Seq_K562_Human1.89509489
24EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.85361212
25P300_27058665_Chip-Seq_ZR-75-30cells_Human1.82825364
26SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.80156492
27EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.80057712
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.78597967
29TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.75551952
30NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.74831077
31EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.73841001
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72132929
33KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.69071544
34RACK7_27058665_Chip-Seq_MCF-7_Human1.66643305
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.61801851
36UTX_26944678_Chip-Seq_JUKART_Human1.57798937
37CREB1_26743006_Chip-Seq_LNCaP_Human1.57105794
38RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.57098672
39CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.53366949
40CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.50453547
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.48265816
42MAF_26560356_Chip-Seq_TH1_Human1.46898827
43STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.46378809
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.44935323
45KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.40437074
46STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.37945663
47CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.36726284
48NCOR1_26117541_ChIP-Seq_K562_Human1.36654228
49CLOCK_20551151_ChIP-Seq_293T_Human1.35210567
50GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.35104711
51RUNX1_27514584_Chip-Seq_MCF-7_Human1.34489706
52SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.33445380
53TP53_22127205_ChIP-Seq_IMR90_Human1.32779942
54KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32176124
55ATF3_27146783_Chip-Seq_COLON_Human1.31603809
56NFIB_24661679_ChIP-Seq_LUNG_Mouse1.31405565
57RARB_27405468_Chip-Seq_BRAIN_Mouse1.31196657
58PKCTHETA_26484144_Chip-Seq_BREAST_Human1.28461007
59TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.28451588
60KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.28336497
61TET1_21451524_ChIP-Seq_MESCs_Mouse1.28315077
62UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28271973
63ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.27086454
64ERG_21242973_ChIP-ChIP_JURKAT_Human1.26558616
65TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.25694820
66FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.25081942
67E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.24276794
68P68_20966046_ChIP-Seq_HELA_Human1.22235988
69DROSHA_22980978_ChIP-Seq_HELA_Human1.21708374
70MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18702377
71VDR_24763502_ChIP-Seq_THP-1_Human1.17837233
72FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.15636177
73HIF1A_21447827_ChIP-Seq_MCF-7_Human1.14897680
74ISL1_27105846_Chip-Seq_CPCs_Mouse1.14812936
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14514546
76ZFX_18555785_ChIP-Seq_MESCs_Mouse1.13509284
77ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.13395950
78MYC_19079543_ChIP-ChIP_MESCs_Mouse1.12431120
79PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.10952294
80AR_21909140_ChIP-Seq_LNCAP_Human1.10637557
81SMC4_20622854_ChIP-Seq_HELA_Human1.08609348
82RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08345232
83FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.07945180
84XRN2_22483619_ChIP-Seq_HELA_Human1.06456747
85SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06258310
86TBX20_22080862_ChIP-Seq_HEART_Mouse1.06118349
87TBX20_22328084_ChIP-Seq_HEART_Mouse1.06118349
88MYC_18555785_ChIP-Seq_MESCs_Mouse1.05900974
89MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.05544930
90SPI1_23127762_ChIP-Seq_K562_Human1.05503532
91TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05339268
92ESR2_21235772_ChIP-Seq_MCF-7_Human1.04373875
93CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03264015
94ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.03100995
95DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02908864
96TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.02872678
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.02851589
98SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02267178
99ESR1_15608294_ChIP-ChIP_MCF-7_Human1.02094581
100ELF1_20517297_ChIP-Seq_JURKAT_Human1.02055910
101RUNX1_22412390_ChIP-Seq_EML_Mouse1.01824122
102STAT3_1855785_ChIP-Seq_MESCs_Mouse1.01249256
103THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.01031453
104CHD1_26751641_Chip-Seq_LNCaP_Human1.00259684
105CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99047802
106* CIITA_25753668_ChIP-Seq_RAJI_Human0.98929690
107GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98161155
108SA1_27219007_Chip-Seq_ERYTHROID_Human0.97995025
109BRD4_27068464_Chip-Seq_AML-cells_Mouse0.97889779
110POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.97325033
111WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95839541
112NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95300550
113MAF_26560356_Chip-Seq_TH2_Human0.93790160
114MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.93207686
115KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.92562383
116SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92454379
117VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91678944
118UBF1/2_26484160_Chip-Seq_HMECs_Human0.91191862
119GATA1_19941826_ChIP-Seq_K562_Human0.90994498
120SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90356011
121SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90183130
122NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.89960339
123TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89854043
124NANOG_21062744_ChIP-ChIP_HESCs_Human0.89659280
125FOXO3_23340844_ChIP-Seq_DLD1_Human0.89000182
126CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88717413
127TP53_23651856_ChIP-Seq_MEFs_Mouse0.87821995
128SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.87466183
129TP63_22573176_ChIP-Seq_HFKS_Human0.86527214

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.20827661
2MP0005076_abnormal_cell_differentiation3.63790889
3MP0010352_gastrointestinal_tract_polyps2.70570028
4MP0005451_abnormal_body_composition2.69049470
5MP0008961_abnormal_basal_metabolism2.57907627
6MP0009278_abnormal_bone_marrow2.55494921
7MP0005623_abnormal_meninges_morphology2.53141912
8MP0003300_gastrointestinal_ulcer2.52232873
9MP0005409_darkened_coat_color2.27508184
10MP0000537_abnormal_urethra_morphology2.20854219
11MP0003283_abnormal_digestive_organ2.13945644
12MP0001849_ear_inflammation2.09567822
13MP0010234_abnormal_vibrissa_follicle2.05830425
14MP0002249_abnormal_larynx_morphology2.04439245
15MP0002653_abnormal_ependyma_morphology2.03904309
16MP0000733_abnormal_muscle_development2.01518811
17MP0000569_abnormal_digit_pigmentation2.00903606
18MP0000678_abnormal_parathyroid_gland1.94257609
19MP0004233_abnormal_muscle_weight1.86189450
20MP0002009_preneoplasia1.85264884
21MP0003115_abnormal_respiratory_system1.80417536
22MP0004197_abnormal_fetal_growth/weight/1.78318848
23MP0009780_abnormal_chondrocyte_physiolo1.74778944
24MP0003566_abnormal_cell_adhesion1.73977407
25MP0003303_peritoneal_inflammation1.72753510
26MP0004858_abnormal_nervous_system1.59559068
27MP0004859_abnormal_synaptic_plasticity1.57367260
28MP0002084_abnormal_developmental_patter1.56370306
29MP0001730_embryonic_growth_arrest1.55803663
30MP0010030_abnormal_orbit_morphology1.55695552
31MP0010307_abnormal_tumor_latency1.51509028
32MP0000566_synostosis1.50512478
33MP0000428_abnormal_craniofacial_morphol1.49022169
34MP0004808_abnormal_hematopoietic_stem1.47914421
35MP0003123_paternal_imprinting1.46379307
36MP0003453_abnormal_keratinocyte_physiol1.45782789
37MP0004264_abnormal_extraembryonic_tissu1.44990989
38MP0009053_abnormal_anal_canal1.40116318
39MP0003091_abnormal_cell_migration1.36445856
40MP0000003_abnormal_adipose_tissue1.36212519
41MP0000534_abnormal_ureter_morphology1.35791980
42MP0005058_abnormal_lysosome_morphology1.33978692
43MP0005257_abnormal_intraocular_pressure1.33201466
44MP0003984_embryonic_growth_retardation1.33071354
45MP0002085_abnormal_embryonic_tissue1.32732271
46MP0002088_abnormal_embryonic_growth/wei1.31872677
47MP0002234_abnormal_pharynx_morphology1.31345855
48MP0004957_abnormal_blastocyst_morpholog1.30696720
49MP0004185_abnormal_adipocyte_glucose1.30170085
50MP0003119_abnormal_digestive_system1.30065554
51MP0002086_abnormal_extraembryonic_tissu1.29251629
52MP0003693_abnormal_embryo_hatching1.29103955
53MP0003045_fibrosis1.28968376
54MP0005380_embryogenesis_phenotype1.28894594
55MP0001672_abnormal_embryogenesis/_devel1.28894594
56MP0002877_abnormal_melanocyte_morpholog1.28141697
57MP0008260_abnormal_autophagy1.27418893
58MP0010630_abnormal_cardiac_muscle1.26768690
59MP0002925_abnormal_cardiovascular_devel1.25590809
60MP0009672_abnormal_birth_weight1.25261541
61MP0001346_abnormal_lacrimal_gland1.23565047
62MP0002796_impaired_skin_barrier1.23007558
63MP0000350_abnormal_cell_proliferation1.22458166
64MP0005621_abnormal_cell_physiology1.21955264
65MP0008877_abnormal_DNA_methylation1.18832853
66MP0005375_adipose_tissue_phenotype1.18608655
67MP0010094_abnormal_chromosome_stability1.18438871
68MP0002089_abnormal_postnatal_growth/wei1.18052087
69MP0001697_abnormal_embryo_size1.16588571
70MP0000751_myopathy1.16363348
71MP0003111_abnormal_nucleus_morphology1.15881852
72MP0004087_abnormal_muscle_fiber1.13958040
73MP0005187_abnormal_penis_morphology1.13718579
74MP0003935_abnormal_craniofacial_develop1.12791895
75MP0008438_abnormal_cutaneous_collagen1.12772078
76MP0001915_intracranial_hemorrhage1.11845321
77MP0009703_decreased_birth_body1.11141551
78MP0003942_abnormal_urinary_system1.10308338
79MP0003385_abnormal_body_wall1.09871791
80MP0003172_abnormal_lysosome_physiology1.08456118
81MP0002060_abnormal_skin_morphology1.08251485
82MP0003279_aneurysm1.07874650
83MP0003121_genomic_imprinting1.07609055
84MP0002166_altered_tumor_susceptibility1.06192054
85MP0006054_spinal_hemorrhage1.05870315
86MP0002080_prenatal_lethality1.04455414
87MP0003122_maternal_imprinting1.04438548
88MP0008057_abnormal_DNA_replication1.03285125
89MP0005023_abnormal_wound_healing1.02344150
90MP0000266_abnormal_heart_morphology1.01439900
91MP0003329_amyloid_beta_deposits1.01379913
92MP0005501_abnormal_skin_physiology1.01230927
93MP0005666_abnormal_adipose_tissue0.99614125
94MP0004947_skin_inflammation0.98949853
95MP0003861_abnormal_nervous_system0.98907927
96MP0004272_abnormal_basement_membrane0.98861780
97MP0008770_decreased_survivor_rate0.98712282
98MP0002396_abnormal_hematopoietic_system0.95607194
99MP0001348_abnormal_lacrimal_gland0.95429248
100MP0004084_abnormal_cardiac_muscle0.95409686
101MP0001545_abnormal_hematopoietic_system0.95208261
102MP0005397_hematopoietic_system_phenotyp0.95208261
103MP0005670_abnormal_white_adipose0.94579811
104MP0002092_abnormal_eye_morphology0.94381834
105MP0002697_abnormal_eye_size0.94013568
106MP0008932_abnormal_embryonic_tissue0.92607771
107MP0000747_muscle_weakness0.92442656
108MP0000579_abnormal_nail_morphology0.91901407
109MP0002909_abnormal_adrenal_gland0.91758828
110MP0001784_abnormal_fluid_regulation0.89969966
111MP0003787_abnormal_imprinting0.88852962
112MP0000858_altered_metastatic_potential0.85769988
113MP0003567_abnormal_fetal_cardiomyocyte0.85067161
114MP0000313_abnormal_cell_death0.81834502
115MP0001958_emphysema0.81526650
116MP0002896_abnormal_bone_mineralization0.80080616
117MP0009931_abnormal_skin_appearance0.79889903
118MP0002932_abnormal_joint_morphology0.79494427
119MP0005384_cellular_phenotype0.78412267
120MP0003763_abnormal_thymus_physiology0.77626996
121MP0000703_abnormal_thymus_morphology0.76726201
122MP0005377_hearing/vestibular/ear_phenot0.76358964
123MP0003878_abnormal_ear_physiology0.76358964
124MP0002116_abnormal_craniofacial_bone0.76095726
125MP0001299_abnormal_eye_distance/0.74929587
126MP0002114_abnormal_axial_skeleton0.74227529
127MP0001873_stomach_inflammation0.72493609
128MP0002269_muscular_atrophy0.71836902
129MP0005248_abnormal_Harderian_gland0.71653101
130MP0000432_abnormal_head_morphology0.71480745
131MP0003077_abnormal_cell_cycle0.70415991
132MP0002128_abnormal_blood_circulation0.70172267
133MP0004130_abnormal_muscle_cell0.69899133
134MP0000759_abnormal_skeletal_muscle0.69632653
135MP0000467_abnormal_esophagus_morphology0.69337446

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)4.11253832
2Cerebral aneurysm (HP:0004944)3.44436215
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.39899921
4Short 4th metacarpal (HP:0010044)3.39899921
5Broad face (HP:0000283)3.34250356
6Shallow orbits (HP:0000586)3.33030196
7Obstructive sleep apnea (HP:0002870)3.20039747
8Renal duplication (HP:0000075)3.03083588
9Elfin facies (HP:0004428)2.96875798
10Renovascular hypertension (HP:0100817)2.92705936
11Macroorchidism (HP:0000053)2.89324432
12Insomnia (HP:0100785)2.87619847
13Abnormality of the lower motor neuron (HP:0002366)2.78126638
14Abnormality of the 4th metacarpal (HP:0010012)2.76380920
15Protrusio acetabuli (HP:0003179)2.76333190
16Upper limb amyotrophy (HP:0009129)2.69443365
17Distal upper limb amyotrophy (HP:0007149)2.69443365
18Overriding aorta (HP:0002623)2.62200205
19Hand muscle atrophy (HP:0009130)2.56222061
20Pointed chin (HP:0000307)2.55496972
21Bladder diverticulum (HP:0000015)2.52989375
22Bowel diverticulosis (HP:0005222)2.51613493
23Flat acetabular roof (HP:0003180)2.51194608
24Increased nuchal translucency (HP:0010880)2.49506318
25Abnormality of the distal phalanx of the thumb (HP:0009617)2.49035471
26Ankle contracture (HP:0006466)2.47113629
27Heterotopia (HP:0002282)2.44518293
28Distal lower limb amyotrophy (HP:0008944)2.40947856
29Neoplasm of the heart (HP:0100544)2.37635351
30Abnormality of the fingertips (HP:0001211)2.30667358
31Astrocytoma (HP:0009592)2.28473905
32Abnormality of the astrocytes (HP:0100707)2.28473905
33Mitral valve prolapse (HP:0001634)2.26102499
34Asymmetry of the thorax (HP:0001555)2.25988161
35Trigonocephaly (HP:0000243)2.25371433
36Enlarged penis (HP:0000040)2.23372641
37Flat cornea (HP:0007720)2.20880158
38Dysmetric saccades (HP:0000641)2.18360298
39Ependymoma (HP:0002888)2.18148855
40Long eyelashes (HP:0000527)2.14923519
41Increased density of long bones (HP:0006392)2.14871537
42Pseudobulbar signs (HP:0002200)2.12768264
43Genu recurvatum (HP:0002816)2.12484418
44Hallux valgus (HP:0001822)2.12393031
45Deviation of the hallux (HP:0010051)2.12209785
46Ankyloglossia (HP:0010296)2.11885639
47Lymphangioma (HP:0100764)2.10824078
48Patellar dislocation (HP:0002999)2.10164790
49Urethral obstruction (HP:0000796)2.10146637
50Centrally nucleated skeletal muscle fibers (HP:0003687)2.08209665
51Aneurysm (HP:0002617)2.07686634
52Lower limb amyotrophy (HP:0007210)2.06745467
53Advanced eruption of teeth (HP:0006288)2.04711959
54Dilatation of the ascending aorta (HP:0005111)2.03104548
55Aortic aneurysm (HP:0004942)2.01976516
56Ulnar bowing (HP:0003031)1.99594564
57Bronchomalacia (HP:0002780)1.99342916
58Broad metatarsal (HP:0001783)1.98530847
59Obsessive-compulsive behavior (HP:0000722)1.98339440
60Dislocated radial head (HP:0003083)1.98189401
61Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.94796285
62Narrow palate (HP:0000189)1.94770967
63Abnormality of oral frenula (HP:0000190)1.93930718
64Sparse lateral eyebrow (HP:0005338)1.93324678
65Bowel incontinence (HP:0002607)1.92042475
66Rectal prolapse (HP:0002035)1.91412588
67Broad thumb (HP:0011304)1.90286609
68Thin ribs (HP:0000883)1.89087303
69Subacute progressive viral hepatitis (HP:0006572)1.87971956
70Broad palm (HP:0001169)1.87394598
71Deep palmar crease (HP:0006191)1.87177261
72Difficulty running (HP:0009046)1.83942126
73Abnormality of the radial head (HP:0003995)1.82436665
74Fibroma (HP:0010614)1.82048839
75Abnormality of the diencephalon (HP:0010662)1.81780354
76Persistence of primary teeth (HP:0006335)1.81596452
77Vertebral arch anomaly (HP:0008438)1.81593988
78Metaphyseal cupping (HP:0003021)1.81507174
79Biconcave vertebral bodies (HP:0004586)1.81234081
80Abnormality of the calcaneus (HP:0008364)1.81158700
81Cholecystitis (HP:0001082)1.80910356
82Abnormal gallbladder physiology (HP:0012438)1.80910356
83Abnormality of the phalanges of the hallux (HP:0010057)1.80773292
84Annular pancreas (HP:0001734)1.80436856
85Sacral dimple (HP:0000960)1.77952736
86Reticulocytosis (HP:0001923)1.77051116
87Fibrous tissue neoplasm (HP:0012316)1.77016753
88Disproportionate tall stature (HP:0001519)1.76125995
89Truncus arteriosus (HP:0001660)1.75431553
90Short phalanx of the thumb (HP:0009660)1.75337715
91Abnormality of the Achilles tendon (HP:0005109)1.75003780
92High pitched voice (HP:0001620)1.74945186
93Arnold-Chiari malformation (HP:0002308)1.74338607
94Abnormal large intestine physiology (HP:0012700)1.74272924
95Megalocornea (HP:0000485)1.73547621
96Increased connective tissue (HP:0009025)1.72781371
97Premature skin wrinkling (HP:0100678)1.72420941
98Abnormality of the thoracic spine (HP:0100711)1.72108143
99Cerebral inclusion bodies (HP:0100314)1.69546634
100Fragile skin (HP:0001030)1.69089605
101Skin tags (HP:0010609)1.68663529
102Mitral regurgitation (HP:0001653)1.67421220
103Difficulty climbing stairs (HP:0003551)1.66936367
104Turricephaly (HP:0000262)1.66645925
105Termporal pattern (HP:0011008)1.65668859
106Insidious onset (HP:0003587)1.65668859
107Spinal cord lesions (HP:0100561)1.65348659
108Syringomyelia (HP:0003396)1.65348659
109Cervical subluxation (HP:0003308)1.64174514
110Buphthalmos (HP:0000557)1.63170185
111Deviation of the thumb (HP:0009603)1.62890228
112Thin bony cortex (HP:0002753)1.62397373
113Relative macrocephaly (HP:0004482)1.61967813
114Increased variability in muscle fiber diameter (HP:0003557)1.61675772
115High anterior hairline (HP:0009890)1.60848111
116Abnormal ossification of hand bones (HP:0005921)1.60146650
117Broad distal phalanx of finger (HP:0009836)1.59383911
118Vertebral compression fractures (HP:0002953)1.59372182
119Selective tooth agenesis (HP:0001592)1.58831868
120Proximal placement of thumb (HP:0009623)1.57541719
121Natal tooth (HP:0000695)1.57230673
122Broad phalanges of the hand (HP:0009768)1.56990869
123Striae distensae (HP:0001065)1.56591733
124Supernumerary ribs (HP:0005815)1.56177708
125Blue sclerae (HP:0000592)1.56175328
126Midface retrusion (HP:0011800)1.55852626
127Spina bifida occulta (HP:0003298)1.55739887
128Premature rupture of membranes (HP:0001788)1.55432834
129Septate vagina (HP:0001153)1.54652669
130Mildly elevated creatine phosphokinase (HP:0008180)1.54587919
131Malignant gastrointestinal tract tumors (HP:0006749)1.54468207
132Gastrointestinal carcinoma (HP:0002672)1.54468207
133Glioma (HP:0009733)1.54440675
134Bicuspid aortic valve (HP:0001647)1.54229259
135Abnormality of the distal phalanges of the toes (HP:0010182)1.54085387
136Achilles tendon contracture (HP:0001771)1.53972345
137Resting tremor (HP:0002322)1.53866935
138Skull defect (HP:0001362)1.53590332
139Spinal rigidity (HP:0003306)1.53445582
140Abnormality of the salivary glands (HP:0010286)1.53415192
141Trismus (HP:0000211)1.52607079
142Long toe (HP:0010511)1.52110459
143Precocious puberty (HP:0000826)1.50835687
144Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.49974023
145Absent frontal sinuses (HP:0002688)1.49836952
146Long palpebral fissure (HP:0000637)1.48855743
147Milia (HP:0001056)1.48411016
148Hyporeflexia of lower limbs (HP:0002600)1.48197147
149Male infertility (HP:0003251)1.46626165
150Neoplasm of the oral cavity (HP:0100649)1.46173460
151Germ cell neoplasia (HP:0100728)1.46129528
152Genetic anticipation (HP:0003743)1.45857167
153Broad finger (HP:0001500)1.45801739

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.36937058
2SMG13.95417690
3CDK123.95245167
4EEF2K3.90021697
5MAP3K103.62555873
6PKN23.35291880
7PRPF4B3.00713350
8ICK2.85961450
9PRKD32.43566990
10RIPK12.22991428
11PTK61.88790398
12CAMK1G1.87850168
13IRAK31.86797178
14PDGFRA1.84848880
15TTN1.83863451
16ERN11.81048439
17SIK11.79030273
18SIK21.72697946
19TYRO31.68896224
20ALK1.64625091
21MTOR1.60753401
22BRD41.57946946
23TAOK11.51954202
24CAMK1D1.48730177
25NEK21.42993436
26BMX1.41658069
27LATS11.27878722
28EPHA21.20724909
29LATS21.16690035
30DMPK1.15806097
31SCYL21.15610201
32PAK41.11390165
33MAP3K91.08652412
34CDC71.07126197
35PAK21.05836284
36MAP3K131.03689771
37MAP3K71.02770247
38PAK61.02115367
39KSR20.96554647
40CDK60.95049984
41CDK40.94620416
42RET0.92045632
43DDR20.91917375
44CAMKK10.91413176
45LRRK20.89398237
46PDGFRB0.88670893
47PTK20.86410157
48FGFR10.85715193
49MAP4K10.85343655
50EPHB10.84149780
51MAP2K30.83986042
52TAOK20.83536567
53PRKCH0.82964225
54MARK20.81445421
55TESK10.80310059
56CDC42BPA0.78437296
57RIPK40.78244815
58MST1R0.77775280
59NEK10.76658287
60EPHB20.75652883
61KSR10.74429255
62STK380.73516197
63FGFR40.72244992
64FGFR30.70808700
65PNCK0.69881491
66MAPK110.69671159
67PDPK10.68021159
68STK100.66092422
69PASK0.65207650
70FGFR20.64719624
71LMTK20.63230965
72NTRK20.62741997
73RPS6KB20.62575080
74BRAF0.61460083
75STK30.60471760
76ARAF0.59937568
77CHEK10.59410710
78MAP3K10.59225064
79RPS6KA20.58166931
80RPS6KC10.57710644
81RPS6KL10.57710644
82NME20.57071193
83WNK10.56636173
84SIK30.56490006
85IRAK20.55806237
86MAP3K80.54510789
87DYRK1B0.52905572
88NTRK10.52728715
89PTK2B0.52222881
90PDK40.51827199
91PDK30.51827199
92STK110.51521325
93ERBB20.50881958
94DAPK20.50666251
95SGK30.50429847
96MAP2K20.50178837
97TNK20.49205746
98TESK20.48797380
99PRKD20.48467057
100CLK10.47974551
101CDK90.46864663
102* CDK20.46588756
103RPS6KA10.45182207
104UHMK10.43775234
105MAP3K60.42773077
106MAP3K20.42294037
107CSNK1D0.41774693
108TTK0.41555853
109RAF10.41500098
110PRKD10.41194837
111GRK60.41051350
112CDK10.40809613
113MET0.40615107
114MAPK80.39631224
115CHUK0.39029831
116CHEK20.38377703
117HCK0.37949164
118HIPK20.37356881
119PDK10.37049422
120GSK3B0.36241414
121RPS6KA60.36130063
122MAPK140.35526586
123BRSK10.35454379
124AKT20.35384965
125PRKDC0.35346808
126MAPK10.35314704
127CDK11A0.34812018
128CSNK1E0.34563567
129CDK70.34453723
130CAMK40.34124882
131ATR0.32233633
132SRC0.32156660
133MAPK100.32013384
134CDK150.32012889

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052201.89056716
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84741589
3Lysine degradation_Homo sapiens_hsa003101.73028881
4mTOR signaling pathway_Homo sapiens_hsa041501.72655021
5Dorso-ventral axis formation_Homo sapiens_hsa043201.64552167
6Notch signaling pathway_Homo sapiens_hsa043301.61166514
7Thyroid hormone signaling pathway_Homo sapiens_hsa049191.55000714
8Glioma_Homo sapiens_hsa052141.53654539
9Endometrial cancer_Homo sapiens_hsa052131.46833069
10Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.42256266
11Basal cell carcinoma_Homo sapiens_hsa052171.42208538
12Proteoglycans in cancer_Homo sapiens_hsa052051.41302132
13Non-small cell lung cancer_Homo sapiens_hsa052231.40717646
14Central carbon metabolism in cancer_Homo sapiens_hsa052301.40271441
15Neurotrophin signaling pathway_Homo sapiens_hsa047221.39980846
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37764641
17Adherens junction_Homo sapiens_hsa045201.36478528
18Estrogen signaling pathway_Homo sapiens_hsa049151.36260745
19Focal adhesion_Homo sapiens_hsa045101.32436961
20Type II diabetes mellitus_Homo sapiens_hsa049301.31757635
21Prion diseases_Homo sapiens_hsa050201.28964787
22MicroRNAs in cancer_Homo sapiens_hsa052061.28923402
23VEGF signaling pathway_Homo sapiens_hsa043701.27915972
24Colorectal cancer_Homo sapiens_hsa052101.26317410
25mRNA surveillance pathway_Homo sapiens_hsa030151.22529652
26Small cell lung cancer_Homo sapiens_hsa052221.22371424
27Hippo signaling pathway_Homo sapiens_hsa043901.22286242
28Other glycan degradation_Homo sapiens_hsa005111.17925624
29Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.17310699
30Renal cell carcinoma_Homo sapiens_hsa052111.16927988
31Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15297313
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.15282194
33Acute myeloid leukemia_Homo sapiens_hsa052211.13515969
34Insulin resistance_Homo sapiens_hsa049311.13377437
35Viral myocarditis_Homo sapiens_hsa054161.12683721
36AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.12570194
37Hedgehog signaling pathway_Homo sapiens_hsa043401.11562293
38Longevity regulating pathway - mammal_Homo sapiens_hsa042111.10849822
39Pancreatic cancer_Homo sapiens_hsa052121.10207593
40B cell receptor signaling pathway_Homo sapiens_hsa046621.09362572
41Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05595466
42Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.05143692
43Bladder cancer_Homo sapiens_hsa052191.05032765
44Biosynthesis of amino acids_Homo sapiens_hsa012301.04983515
45Pentose phosphate pathway_Homo sapiens_hsa000301.04697102
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.04084370
47Aldosterone synthesis and secretion_Homo sapiens_hsa049251.04010862
48Carbohydrate digestion and absorption_Homo sapiens_hsa049731.02910717
49ErbB signaling pathway_Homo sapiens_hsa040121.02186954
50Cell cycle_Homo sapiens_hsa041101.01660267
51Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.01518315
52Insulin signaling pathway_Homo sapiens_hsa049101.01474090
53Nitrogen metabolism_Homo sapiens_hsa009101.00682361
54HTLV-I infection_Homo sapiens_hsa051661.00494651
55Inositol phosphate metabolism_Homo sapiens_hsa005621.00004886
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99929418
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96865763
58DNA replication_Homo sapiens_hsa030300.96587877
59Long-term potentiation_Homo sapiens_hsa047200.96512449
60Glucagon signaling pathway_Homo sapiens_hsa049220.95480045
61Amoebiasis_Homo sapiens_hsa051460.94553901
62AMPK signaling pathway_Homo sapiens_hsa041520.93350831
63Dilated cardiomyopathy_Homo sapiens_hsa054140.92712857
64ECM-receptor interaction_Homo sapiens_hsa045120.92106320
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.90549257
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.89896366
67Prolactin signaling pathway_Homo sapiens_hsa049170.89568460
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88843621
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.87053507
70Melanogenesis_Homo sapiens_hsa049160.86508000
71Wnt signaling pathway_Homo sapiens_hsa043100.85982782
72cGMP-PKG signaling pathway_Homo sapiens_hsa040220.85583737
73Gastric acid secretion_Homo sapiens_hsa049710.85561036
74Oocyte meiosis_Homo sapiens_hsa041140.84913044
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.84661661
76Axon guidance_Homo sapiens_hsa043600.84553984
77Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.83720478
78Prostate cancer_Homo sapiens_hsa052150.82895437
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82712379
80Gap junction_Homo sapiens_hsa045400.82664159
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82639660
82Rap1 signaling pathway_Homo sapiens_hsa040150.80735572
83T cell receptor signaling pathway_Homo sapiens_hsa046600.80703712
84Fructose and mannose metabolism_Homo sapiens_hsa000510.80401164
85GnRH signaling pathway_Homo sapiens_hsa049120.80218679
86Toxoplasmosis_Homo sapiens_hsa051450.79834879
87Platelet activation_Homo sapiens_hsa046110.79786702
88Tight junction_Homo sapiens_hsa045300.79101451
89HIF-1 signaling pathway_Homo sapiens_hsa040660.78662703
90Oxytocin signaling pathway_Homo sapiens_hsa049210.78464602
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.77430214
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.77411707
93Pathways in cancer_Homo sapiens_hsa052000.77146648
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.77038926
95Thyroid cancer_Homo sapiens_hsa052160.76680609
96Endocytosis_Homo sapiens_hsa041440.76614526
97Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.75725448
98Apoptosis_Homo sapiens_hsa042100.75179622
99MAPK signaling pathway_Homo sapiens_hsa040100.74719098
100Hepatitis C_Homo sapiens_hsa051600.72197982
101Sphingolipid signaling pathway_Homo sapiens_hsa040710.68712419
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67700537
103Choline metabolism in cancer_Homo sapiens_hsa052310.66985238
104Viral carcinogenesis_Homo sapiens_hsa052030.66370024
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.66264819
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.65674419
107Osteoclast differentiation_Homo sapiens_hsa043800.65596698
108Hepatitis B_Homo sapiens_hsa051610.65327341
109FoxO signaling pathway_Homo sapiens_hsa040680.65121562
110Influenza A_Homo sapiens_hsa051640.63510304
111Renin secretion_Homo sapiens_hsa049240.63327650
112Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.62713143
113Insulin secretion_Homo sapiens_hsa049110.61553817
114Fatty acid biosynthesis_Homo sapiens_hsa000610.60612465
115cAMP signaling pathway_Homo sapiens_hsa040240.60094909
116Melanoma_Homo sapiens_hsa052180.59908845
117Dopaminergic synapse_Homo sapiens_hsa047280.59507004
118Spliceosome_Homo sapiens_hsa030400.59503933
119TGF-beta signaling pathway_Homo sapiens_hsa043500.59269298
120Cholinergic synapse_Homo sapiens_hsa047250.57136058
121Thyroid hormone synthesis_Homo sapiens_hsa049180.56832256
122Cocaine addiction_Homo sapiens_hsa050300.56407033
1232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.53719335
124Shigellosis_Homo sapiens_hsa051310.52128602
125Toll-like receptor signaling pathway_Homo sapiens_hsa046200.49134312

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »