PRRT3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.32606285
2synaptic vesicle maturation (GO:0016188)5.84792239
3vocalization behavior (GO:0071625)5.75444427
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.68974411
5behavioral response to nicotine (GO:0035095)5.56402324
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.48620976
7locomotory exploration behavior (GO:0035641)5.47573223
8synaptic vesicle exocytosis (GO:0016079)5.45023072
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.37752972
10neuronal action potential propagation (GO:0019227)5.21211189
11glutamate secretion (GO:0014047)5.13924889
12protein localization to synapse (GO:0035418)5.02876520
13ionotropic glutamate receptor signaling pathway (GO:0035235)5.02850014
14regulation of synaptic vesicle exocytosis (GO:2000300)4.96748586
15regulation of glutamate receptor signaling pathway (GO:1900449)4.92231965
16neuron cell-cell adhesion (GO:0007158)4.71794776
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.67108093
18glutamate receptor signaling pathway (GO:0007215)4.59070427
19axonemal dynein complex assembly (GO:0070286)4.58891028
20neurotransmitter secretion (GO:0007269)4.50220244
21regulation of neuronal synaptic plasticity (GO:0048168)4.50156356
22regulation of long-term neuronal synaptic plasticity (GO:0048169)4.48890181
23synaptic transmission, glutamatergic (GO:0035249)4.46393924
24regulation of synaptic vesicle transport (GO:1902803)4.39003447
25exploration behavior (GO:0035640)4.38051155
26neuron-neuron synaptic transmission (GO:0007270)4.22222600
27layer formation in cerebral cortex (GO:0021819)4.20448941
28gamma-aminobutyric acid transport (GO:0015812)4.12185597
29regulation of female receptivity (GO:0045924)4.05675695
30transmission of nerve impulse (GO:0019226)4.04411249
31proline transport (GO:0015824)4.04262646
32cellular potassium ion homeostasis (GO:0030007)4.02944516
33regulation of synapse structural plasticity (GO:0051823)4.01804223
34regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.01449995
35regulation of excitatory postsynaptic membrane potential (GO:0060079)3.97680657
36dendritic spine morphogenesis (GO:0060997)3.97175349
37long-term memory (GO:0007616)3.96950366
38gamma-aminobutyric acid signaling pathway (GO:0007214)3.96915903
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.96225141
40cellular response to ATP (GO:0071318)3.89121060
41axoneme assembly (GO:0035082)3.86175799
42neurotransmitter-gated ion channel clustering (GO:0072578)3.85612670
43positive regulation of membrane potential (GO:0045838)3.85344198
44regulation of postsynaptic membrane potential (GO:0060078)3.80348710
45cilium movement (GO:0003341)3.76783275
46neuron recognition (GO:0008038)3.76013812
47epithelial cilium movement (GO:0003351)3.75081172
48positive regulation of synapse maturation (GO:0090129)3.72297535
49epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.69956791
50neurotransmitter transport (GO:0006836)3.67289891
51regulation of synaptic plasticity (GO:0048167)3.66368658
52protein polyglutamylation (GO:0018095)3.65444719
53sodium ion export (GO:0071436)3.64622489
54regulation of dendritic spine morphogenesis (GO:0061001)3.63867104
55G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.63085266
56cerebellar Purkinje cell differentiation (GO:0021702)3.59739811
57neuromuscular process controlling balance (GO:0050885)3.58276173
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.58113132
59female mating behavior (GO:0060180)3.54866465
60synaptic vesicle endocytosis (GO:0048488)3.54654057
61neuromuscular process controlling posture (GO:0050884)3.53909173
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.53708655
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.43823674
64regulation of neurotransmitter secretion (GO:0046928)3.41996389
65activation of protein kinase A activity (GO:0034199)3.40086827
66regulation of neurotransmitter levels (GO:0001505)3.38973652
67long-term synaptic potentiation (GO:0060291)3.38734119
68axonal fasciculation (GO:0007413)3.38454394
69regulation of vesicle fusion (GO:0031338)3.37672570
70cilium or flagellum-dependent cell motility (GO:0001539)3.36868513
71positive regulation of synaptic transmission, GABAergic (GO:0032230)3.36863831
72membrane depolarization during action potential (GO:0086010)3.35411140
73postsynaptic membrane organization (GO:0001941)3.33045269
74cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.32626736
75membrane depolarization (GO:0051899)3.32532534
76positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.29464447
77cellular anion homeostasis (GO:0030002)3.24548855
78positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.24327927
79behavioral fear response (GO:0001662)3.23003437
80behavioral defense response (GO:0002209)3.23003437
81neuronal ion channel clustering (GO:0045161)3.22321858
82cell communication by electrical coupling (GO:0010644)3.21697475
83innervation (GO:0060384)3.21337962
84G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.20856559
85DNA deamination (GO:0045006)3.20758541
86positive regulation of neurotransmitter secretion (GO:0001956)3.18726076
87auditory behavior (GO:0031223)3.15275520
88positive regulation of dendritic spine development (GO:0060999)3.13349569
89response to histamine (GO:0034776)3.13258890
90regulation of neurotransmitter transport (GO:0051588)3.13105616
91learning (GO:0007612)3.13089870
92presynaptic membrane assembly (GO:0097105)3.13040268
93synapse assembly (GO:0007416)3.12685201
94regulation of dendritic spine development (GO:0060998)3.12225407
95ubiquinone biosynthetic process (GO:0006744)3.11845290
96synaptic transmission (GO:0007268)3.11787193
97water-soluble vitamin biosynthetic process (GO:0042364)3.11332588
98positive regulation of neurotransmitter transport (GO:0051590)3.10583690
99membrane hyperpolarization (GO:0060081)3.09897835
100protein localization to cilium (GO:0061512)3.09310907
101dendritic spine organization (GO:0097061)3.08566333
102chemosensory behavior (GO:0007635)3.07014245
103fear response (GO:0042596)3.05897176
104neuromuscular process (GO:0050905)3.05885978
105glycine transport (GO:0015816)3.05601774
106regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.05367396
107positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.05183608
108cell migration in hindbrain (GO:0021535)3.04903932
109regulation of synaptic transmission (GO:0050804)3.04562032
110vesicle transport along microtubule (GO:0047496)3.04466245
111motile cilium assembly (GO:0044458)3.03887529
112protein complex biogenesis (GO:0070271)3.03477276
113negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.03159819
114response to auditory stimulus (GO:0010996)3.02784174
115prepulse inhibition (GO:0060134)2.99597684
116social behavior (GO:0035176)2.99441548
117intraspecies interaction between organisms (GO:0051703)2.99441548
118regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.99431241
119neuronal action potential (GO:0019228)2.98647434
120long term synaptic depression (GO:0060292)2.97421188
121aggressive behavior (GO:0002118)2.95946885
122protein import into peroxisome matrix (GO:0016558)2.95278758
123adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.90453446
124cellular ketone body metabolic process (GO:0046950)2.88225609
125negative regulation of response to food (GO:0032096)2.84772508
126negative regulation of appetite (GO:0032099)2.84772508
127serotonin metabolic process (GO:0042428)2.78589016
128regulation of neurotransmitter uptake (GO:0051580)2.78113463
129ubiquinone metabolic process (GO:0006743)2.75115210
130opioid receptor signaling pathway (GO:0038003)2.70254427
131mitochondrial respiratory chain complex assembly (GO:0033108)2.69003965
132mitochondrial respiratory chain complex I assembly (GO:0032981)2.68914972
133NADH dehydrogenase complex assembly (GO:0010257)2.68914972
134mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.68914972
135primary amino compound metabolic process (GO:1901160)2.66627728
136response to amphetamine (GO:0001975)2.64288123
137preassembly of GPI anchor in ER membrane (GO:0016254)2.64079005
138chaperone-mediated protein transport (GO:0072321)2.63601836
139regulation of calcium ion-dependent exocytosis (GO:0017158)2.60689327
140regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.58466028
141regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.58466028
142glycosphingolipid biosynthetic process (GO:0006688)2.58268190
143protein-cofactor linkage (GO:0018065)2.57781225
144neuromuscular synaptic transmission (GO:0007274)2.56450161
145glycerophospholipid catabolic process (GO:0046475)2.56319845
146synaptic transmission, cholinergic (GO:0007271)2.55916437
147response to misfolded protein (GO:0051788)2.55608401
148ketone body metabolic process (GO:1902224)2.51482348
149metallo-sulfur cluster assembly (GO:0031163)2.50380204
150iron-sulfur cluster assembly (GO:0016226)2.50380204
151positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.49992221
152calcium ion-dependent exocytosis (GO:0017156)2.45024477
153cornea development in camera-type eye (GO:0061303)2.43368051
154grooming behavior (GO:0007625)2.42516423
155cell proliferation in forebrain (GO:0021846)2.42035306
156ATP synthesis coupled proton transport (GO:0015986)2.41930637
157energy coupled proton transport, down electrochemical gradient (GO:0015985)2.41930637
158base-excision repair, AP site formation (GO:0006285)2.40380004
159pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.40111971
160urinary tract smooth muscle contraction (GO:0014848)2.39617183
161regulation of synapse maturation (GO:0090128)2.38944722
162startle response (GO:0001964)2.38898816
163RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.38038593
164tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.38038593
165multicellular organismal signaling (GO:0035637)2.37212321
166protein insertion into membrane (GO:0051205)2.36910018
167positive regulation of amino acid transport (GO:0051957)2.36852315
168negative regulation of telomere maintenance (GO:0032205)2.36373744
169adult walking behavior (GO:0007628)2.36327622
170regulation of collateral sprouting (GO:0048670)2.34814280

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.79916318
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.66004270
3GBX2_23144817_ChIP-Seq_PC3_Human3.43698958
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.24428324
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.21522937
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.13931365
7REST_21632747_ChIP-Seq_MESCs_Mouse2.88247175
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82963274
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82963274
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.77976224
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.72378496
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.67222830
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.59832376
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58156193
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.57534605
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52830192
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.52002078
18DROSHA_22980978_ChIP-Seq_HELA_Human2.51394365
19IKZF1_21737484_ChIP-ChIP_HCT116_Human2.40145796
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.35176797
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.33348280
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.30098977
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.28325584
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.25815505
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.14207107
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.10178223
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.01989725
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.93497114
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90134599
30* P68_20966046_ChIP-Seq_HELA_Human1.83704996
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.80582201
32TAF15_26573619_Chip-Seq_HEK293_Human1.80000731
33AR_21572438_ChIP-Seq_LNCaP_Human1.77143689
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.74411650
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.70054278
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69357317
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.66199013
38SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.59940916
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59343349
40SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.58353799
41SMAD4_21799915_ChIP-Seq_A2780_Human1.58068425
42ELF1_20517297_ChIP-Seq_JURKAT_Human1.55935643
43EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.54353529
44ERA_21632823_ChIP-Seq_H3396_Human1.53480193
45CTCF_20526341_ChIP-Seq_ESCs_Human1.48946916
46BCL6_27268052_Chip-Seq_Bcells_Human1.46089002
47ZNF274_21170338_ChIP-Seq_K562_Hela1.43589222
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.42742130
49E2F1_20622854_ChIP-Seq_HELA_Human1.40313078
50* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.40138842
51SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.37632867
52* PHF8_20622854_ChIP-Seq_HELA_Human1.36600721
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.36578921
54PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36303951
55RING1B_27294783_Chip-Seq_ESCs_Mouse1.34509739
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.34159709
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.33536362
58TDRD3_21172665_ChIP-Seq_MCF-7_Human1.33310248
59YY1_22570637_ChIP-Seq_MALME-3M_Human1.32817561
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30699352
61IRF1_19129219_ChIP-ChIP_H3396_Human1.29078018
62TP53_20018659_ChIP-ChIP_R1E_Mouse1.27958187
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27913104
64SOX2_21211035_ChIP-Seq_LN229_Gbm1.27671686
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26957191
66P300_19829295_ChIP-Seq_ESCs_Human1.26911838
67TAF2_19829295_ChIP-Seq_ESCs_Human1.26796835
68SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25925680
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25277430
70RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.25136372
71RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.24935495
72SMC4_20622854_ChIP-Seq_HELA_Human1.23594939
73TET1_21451524_ChIP-Seq_MESCs_Mouse1.23142904
74AR_19668381_ChIP-Seq_PC3_Human1.22353067
75IGF1R_20145208_ChIP-Seq_DFB_Human1.21512968
76JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.20972140
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.20938946
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20530919
79LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19696113
80AR_25329375_ChIP-Seq_VCAP_Human1.18858086
81OCT4_19829295_ChIP-Seq_ESCs_Human1.18531869
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.18523185
83ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.17645066
84BCOR_27268052_Chip-Seq_Bcells_Human1.17594960
85STAT3_23295773_ChIP-Seq_U87_Human1.17155956
86TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16756280
87SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16144538
88RING1B_27294783_Chip-Seq_NPCs_Mouse1.15029984
89ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.14343969
90CBX2_27304074_Chip-Seq_ESCs_Mouse1.14285025
91* LXR_22292898_ChIP-Seq_THP-1_Human1.14164231
92CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.13827996
93RNF2_27304074_Chip-Seq_NSC_Mouse1.11750832
94WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10909477
95GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10518342
96KDM2B_26808549_Chip-Seq_K562_Human1.09964779
97* TP53_22573176_ChIP-Seq_HFKS_Human1.09396425
98OCT4_20526341_ChIP-Seq_ESCs_Human1.09046762
99* FOXP1_21924763_ChIP-Seq_HESCs_Human1.08869917
100SA1_27219007_Chip-Seq_Bcells_Human1.07856312
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.07684126
102ZFP281_18757296_ChIP-ChIP_E14_Mouse1.07430958
103P300_27268052_Chip-Seq_Bcells_Human1.07364024
104P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06561237
105SMAD_19615063_ChIP-ChIP_OVARY_Human1.06253873
106PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.06098777
107OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06094057
108TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05828801
109MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.04875131
110PIAS1_25552417_ChIP-Seq_VCAP_Human1.03955144
111WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03811841
112RARB_24833708_ChIP-Seq_LIVER_Mouse1.03693445
113TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03271190
114E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03143136
115* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02849203
116TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02628874
117TCF4_23295773_ChIP-Seq_U87_Human1.02331824
118PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01798837
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01303994
120RAD21_21589869_ChIP-Seq_MESCs_Mouse1.01270747
121CTCF_18555785_ChIP-Seq_MESCs_Mouse1.01004962
122MYC_19829295_ChIP-Seq_ESCs_Human1.00777989
123EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00604466
124PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.99653162
125EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.99550824
126RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99500876
127YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99096914
128MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98519389
129SA1_27219007_Chip-Seq_ERYTHROID_Human0.98196191
130ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97082971
131ZNF217_24962896_ChIP-Seq_MCF-7_Human0.96692268
132ARNT_22903824_ChIP-Seq_MCF-7_Human0.95924136
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.95155862
134NANOG_20526341_ChIP-Seq_ESCs_Human0.93345757
135P53_21459846_ChIP-Seq_SAOS-2_Human0.92794439
136FUS_26573619_Chip-Seq_HEK293_Human0.92425338
137TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91854594
138SMAD3_21741376_ChIP-Seq_HESCs_Human0.91825543
139RUNX2_22187159_ChIP-Seq_PCA_Human0.91315898
140* GATA3_21878914_ChIP-Seq_MCF-7_Human0.91155724
141UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90724613
142AHR_22903824_ChIP-Seq_MCF-7_Human0.90440062
143CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89550774
144SMAD4_21741376_ChIP-Seq_HESCs_Human0.88972735
145CTCF_27219007_Chip-Seq_Bcells_Human0.88242547
146GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87461279
147TET1_21490601_ChIP-Seq_MESCs_Mouse0.86663149
148AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.86591795
149PRDM14_20953172_ChIP-Seq_ESCs_Human0.84436310
150CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84394296
151POU3F2_20337985_ChIP-ChIP_501MEL_Human0.84152552
152SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83786847
153TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.82586976
154* JUN_21703547_ChIP-Seq_K562_Human0.82310185
155NR3C1_21868756_ChIP-Seq_MCF10A_Human0.81672281

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.58632802
2MP0003880_abnormal_central_pattern4.95816349
3MP0003635_abnormal_synaptic_transmissio4.23093310
4MP0004270_analgesia3.88455383
5MP0009745_abnormal_behavioral_response3.54892872
6MP0002063_abnormal_learning/memory/cond3.40002227
7MP0002064_seizures3.25472188
8MP0009046_muscle_twitch3.23540317
9MP0002653_abnormal_ependyma_morphology3.18863448
10MP0001968_abnormal_touch/_nociception3.11123645
11MP0002822_catalepsy2.89103298
12MP0002572_abnormal_emotion/affect_behav2.85907123
13MP0002272_abnormal_nervous_system2.80796563
14MP0002734_abnormal_mechanical_nocicepti2.71697210
15MP0001486_abnormal_startle_reflex2.59450109
16MP0001501_abnormal_sleep_pattern2.52097182
17MP0002735_abnormal_chemical_nociception2.48530420
18MP0002736_abnormal_nociception_after2.46591437
19MP0005423_abnormal_somatic_nervous2.45573019
20MP0001440_abnormal_grooming_behavior2.33346272
21MP0002733_abnormal_thermal_nociception2.17068618
22MP0006292_abnormal_olfactory_placode2.08453216
23MP0001970_abnormal_pain_threshold2.08214194
24MP0002067_abnormal_sensory_capabilities2.05460151
25MP0003329_amyloid_beta_deposits1.90880109
26MP0008569_lethality_at_weaning1.90846624
27MP0002184_abnormal_innervation1.90189630
28MP0004858_abnormal_nervous_system1.86403650
29MP0006276_abnormal_autonomic_nervous1.86166826
30MP0008875_abnormal_xenobiotic_pharmacok1.85543199
31MP0004811_abnormal_neuron_physiology1.73650046
32MP0002557_abnormal_social/conspecific_i1.73627309
33MP0009780_abnormal_chondrocyte_physiolo1.73584414
34MP0002909_abnormal_adrenal_gland1.72424440
35MP0003879_abnormal_hair_cell1.71251169
36MP0005386_behavior/neurological_phenoty1.67516970
37MP0004924_abnormal_behavior1.67516970
38MP0001984_abnormal_olfaction1.67165349
39MP0000778_abnormal_nervous_system1.67046379
40MP0000955_abnormal_spinal_cord1.63809112
41MP0004133_heterotaxia1.57509368
42MP0002160_abnormal_reproductive_system1.45855835
43MP0002066_abnormal_motor_capabilities/c1.45148220
44MP0002882_abnormal_neuron_morphology1.43319307
45MP0005646_abnormal_pituitary_gland1.39317418
46MP0004142_abnormal_muscle_tone1.37643798
47MP0004885_abnormal_endolymph1.37511953
48MP0001986_abnormal_taste_sensitivity1.34581554
49MP0001529_abnormal_vocalization1.34198869
50MP0002163_abnormal_gland_morphology1.33311098
51MP0004145_abnormal_muscle_electrophysio1.31173516
52MP0003633_abnormal_nervous_system1.31062394
53MP0003787_abnormal_imprinting1.26720514
54MP0005645_abnormal_hypothalamus_physiol1.26676595
55MP0004147_increased_porphyrin_level1.25887260
56MP0001502_abnormal_circadian_rhythm1.23470064
57MP0003646_muscle_fatigue1.20409823
58MP0008877_abnormal_DNA_methylation1.19713997
59MP0010386_abnormal_urinary_bladder1.15890002
60MP0005377_hearing/vestibular/ear_phenot1.10611228
61MP0003878_abnormal_ear_physiology1.10611228
62MP0002928_abnormal_bile_duct1.10042689
63MP0003631_nervous_system_phenotype1.09558657
64MP0002152_abnormal_brain_morphology1.08680929
65MP0001905_abnormal_dopamine_level1.07827855
66MP0001188_hyperpigmentation1.05844383
67MP0002229_neurodegeneration1.05022707
68MP0000678_abnormal_parathyroid_gland1.04412861
69MP0008872_abnormal_physiological_respon1.01855396
70MP0003122_maternal_imprinting1.00901295
71MP0006072_abnormal_retinal_apoptosis0.99908322
72MP0004742_abnormal_vestibular_system0.97973394
73MP0009379_abnormal_foot_pigmentation0.97433723
74MP0003011_delayed_dark_adaptation0.97362728
75MP0008874_decreased_physiological_sensi0.97020131
76MP0003283_abnormal_digestive_organ0.96792992
77MP0005174_abnormal_tail_pigmentation0.96327625
78MP0005253_abnormal_eye_physiology0.91808235
79MP0004043_abnormal_pH_regulation0.90156461
80MP0002069_abnormal_eating/drinking_beha0.90010642
81MP0001963_abnormal_hearing_physiology0.89963004
82MP0005551_abnormal_eye_electrophysiolog0.89620112
83MP0000751_myopathy0.89464829
84MP0005389_reproductive_system_phenotype0.87808785
85MP0005084_abnormal_gallbladder_morpholo0.87503272
86MP0005394_taste/olfaction_phenotype0.87298246
87MP0005499_abnormal_olfactory_system0.87298246
88MP0001944_abnormal_pancreas_morphology0.86163358
89MP0003634_abnormal_glial_cell0.85664220
90MP0002693_abnormal_pancreas_physiology0.85569560
91MP0002234_abnormal_pharynx_morphology0.85225962
92MP0008995_early_reproductive_senescence0.84967152
93MP0002249_abnormal_larynx_morphology0.84626777
94MP0002837_dystrophic_cardiac_calcinosis0.84393802
95MP0005220_abnormal_exocrine_pancreas0.82566232
96MP0005379_endocrine/exocrine_gland_phen0.81840916
97MP0000013_abnormal_adipose_tissue0.81571997
98MP0004085_abnormal_heartbeat0.81422260
99MP0000604_amyloidosis0.81007834
100MP0000920_abnormal_myelination0.80732233
101MP0002752_abnormal_somatic_nervous0.80721760
102MP0001485_abnormal_pinna_reflex0.79967611
103MP0005535_abnormal_body_temperature0.78714542
104MP0001177_atelectasis0.77938361
105MP0003632_abnormal_nervous_system0.77458247
106MP0003938_abnormal_ear_development0.76904670
107MP0003123_paternal_imprinting0.75885801
108MP0003075_altered_response_to0.74419284
109MP0008961_abnormal_basal_metabolism0.74376276
110MP0002277_abnormal_respiratory_mucosa0.74019372
111MP0000049_abnormal_middle_ear0.73268588
112MP0001348_abnormal_lacrimal_gland0.71998111
113MP0003690_abnormal_glial_cell0.70720835
114MP0000631_abnormal_neuroendocrine_gland0.69904827
115MP0004510_myositis0.69219769
116MP0004215_abnormal_myocardial_fiber0.67263243
117MP0005409_darkened_coat_color0.65771899
118MP0004484_altered_response_of0.65204134
119MP0004233_abnormal_muscle_weight0.64732372
120MP0002090_abnormal_vision0.63531397
121MP0003137_abnormal_impulse_conducting0.61456909
122MP0005623_abnormal_meninges_morphology0.59235994
123MP0001664_abnormal_digestion0.58835558
124MP0005167_abnormal_blood-brain_barrier0.58386898
125MP0003861_abnormal_nervous_system0.54955052
126MP0001943_abnormal_respiration0.54546459
127MP0002876_abnormal_thyroid_physiology0.54297271
128MP0010769_abnormal_survival0.53886306
129MP0002638_abnormal_pupillary_reflex0.53803709
130MP0000026_abnormal_inner_ear0.52826751
131MP0000569_abnormal_digit_pigmentation0.52535891
132MP0003956_abnormal_body_size0.52073635
133MP0002082_postnatal_lethality0.51661958
134MP0010770_preweaning_lethality0.51661958

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.27275531
2Myokymia (HP:0002411)7.24606578
3Focal seizures (HP:0007359)6.15617027
4Visual hallucinations (HP:0002367)5.63303618
5Atonic seizures (HP:0010819)5.58055033
6Febrile seizures (HP:0002373)5.05194488
7Epileptic encephalopathy (HP:0200134)5.02546633
8Absence seizures (HP:0002121)4.77596758
9Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.76772551
10Dialeptic seizures (HP:0011146)4.34528378
11Progressive cerebellar ataxia (HP:0002073)4.32933838
12Abnormal respiratory motile cilium morphology (HP:0005938)4.27080742
13Abnormal respiratory epithelium morphology (HP:0012253)4.27080742
14Generalized tonic-clonic seizures (HP:0002069)4.24596285
15Action tremor (HP:0002345)4.09404747
16Abnormal respiratory motile cilium physiology (HP:0012261)4.09059074
17Dynein arm defect of respiratory motile cilia (HP:0012255)3.98430003
18Absent/shortened dynein arms (HP:0200106)3.98430003
19Abnormal ciliary motility (HP:0012262)3.63982411
20Supranuclear gaze palsy (HP:0000605)3.53942522
21Gaze-evoked nystagmus (HP:0000640)3.46888400
22Broad-based gait (HP:0002136)3.45349879
23Poor eye contact (HP:0000817)3.42925178
24Rhinitis (HP:0012384)3.38583590
25Pancreatic fibrosis (HP:0100732)3.36164006
26Dysdiadochokinesis (HP:0002075)3.35383067
27True hermaphroditism (HP:0010459)3.35234882
28Pancreatic cysts (HP:0001737)3.32887238
29Dysmetria (HP:0001310)3.25898307
30Impaired vibration sensation in the lower limbs (HP:0002166)3.23372386
31Nephronophthisis (HP:0000090)3.20687950
32Impaired social interactions (HP:0000735)3.19259799
33Abnormal social behavior (HP:0012433)3.19259799
34Hyperventilation (HP:0002883)3.17579210
35Depression (HP:0000716)3.15732365
36Truncal ataxia (HP:0002078)3.09796555
37Abnormality of midbrain morphology (HP:0002418)3.08245830
38Molar tooth sign on MRI (HP:0002419)3.08245830
39Amblyopia (HP:0000646)3.06392060
40Abnormality of the lower motor neuron (HP:0002366)3.04774286
41Ankle clonus (HP:0011448)3.02423612
42Anxiety (HP:0000739)2.96848108
43Chronic bronchitis (HP:0004469)2.96027087
44Hemiparesis (HP:0001269)2.93080332
45Urinary bladder sphincter dysfunction (HP:0002839)2.92718822
46Impaired smooth pursuit (HP:0007772)2.86312378
47Scanning speech (HP:0002168)2.83588133
48Mutism (HP:0002300)2.83310799
49Congenital stationary night blindness (HP:0007642)2.80431034
50Chronic hepatic failure (HP:0100626)2.79261364
51Postural instability (HP:0002172)2.78140876
52Asplenia (HP:0001746)2.74334093
53Cerebral inclusion bodies (HP:0100314)2.72335785
54Aplasia/Hypoplasia of the spleen (HP:0010451)2.69031543
55Status epilepticus (HP:0002133)2.68888499
56Abnormal eating behavior (HP:0100738)2.68176746
57Neurofibrillary tangles (HP:0002185)2.68132548
58Genetic anticipation (HP:0003743)2.65393813
59Excessive salivation (HP:0003781)2.64314060
60Drooling (HP:0002307)2.64314060
61Bronchiectasis (HP:0002110)2.64155015
62Insidious onset (HP:0003587)2.60308441
63Termporal pattern (HP:0011008)2.60308441
64Spastic gait (HP:0002064)2.60166620
65Abnormality of binocular vision (HP:0011514)2.57952538
66Diplopia (HP:0000651)2.57952538
67Epileptiform EEG discharges (HP:0011182)2.53422744
68Urinary urgency (HP:0000012)2.51101900
69Cystic liver disease (HP:0006706)2.50979484
70Abnormal drinking behavior (HP:0030082)2.50100134
71Polydipsia (HP:0001959)2.50100134
72Abnormal mitochondria in muscle tissue (HP:0008316)2.47378198
73Abnormality of ocular smooth pursuit (HP:0000617)2.44776870
74Acute necrotizing encephalopathy (HP:0006965)2.44373149
75Intention tremor (HP:0002080)2.44234912
76Bradykinesia (HP:0002067)2.44086570
77Hyperthyroidism (HP:0000836)2.41737129
78EEG with generalized epileptiform discharges (HP:0011198)2.41522957
793-Methylglutaconic aciduria (HP:0003535)2.40571521
80Annular pancreas (HP:0001734)2.40325674
81Hemiplegia (HP:0002301)2.39231955
82Abnormality of the renal medulla (HP:0100957)2.38327046
83Absent speech (HP:0001344)2.38283743
84Decreased central vision (HP:0007663)2.37239233
85Abnormality of the corticospinal tract (HP:0002492)2.37220266
86Papilledema (HP:0001085)2.36064880
87Torticollis (HP:0000473)2.35930471
88Mitochondrial inheritance (HP:0001427)2.35875054
89Methylmalonic acidemia (HP:0002912)2.35213517
90Stereotypic behavior (HP:0000733)2.35151573
91Ventricular fibrillation (HP:0001663)2.30145338
92Progressive inability to walk (HP:0002505)2.30006021
93Dysmetric saccades (HP:0000641)2.29049078
94Hypsarrhythmia (HP:0002521)2.25103614
95Fetal akinesia sequence (HP:0001989)2.25089652
96Focal dystonia (HP:0004373)2.23816089
97Generalized myoclonic seizures (HP:0002123)2.23581291
98Attenuation of retinal blood vessels (HP:0007843)2.21258858
99Progressive macrocephaly (HP:0004481)2.19728001
100Recurrent sinusitis (HP:0011108)2.19034198
101Impaired vibratory sensation (HP:0002495)2.18633819
102Methylmalonic aciduria (HP:0012120)2.14962923
103Delusions (HP:0000746)2.13858403
104Abnormal rod and cone electroretinograms (HP:0008323)2.13619925
105Resting tremor (HP:0002322)2.08445802
106Bony spicule pigmentary retinopathy (HP:0007737)2.07732737
107Medial flaring of the eyebrow (HP:0010747)2.06394190
108Pheochromocytoma (HP:0002666)2.05887668
109Increased intramyocellular lipid droplets (HP:0012240)2.04906209
110Inability to walk (HP:0002540)2.04726455
111Male pseudohermaphroditism (HP:0000037)2.04258029
112Testicular atrophy (HP:0000029)2.02353623
113Ketoacidosis (HP:0001993)2.02342397
114Lower limb muscle weakness (HP:0007340)2.01423855
115Acute encephalopathy (HP:0006846)2.00630178
116Renal Fanconi syndrome (HP:0001994)1.99146957
117Incomplete penetrance (HP:0003829)1.99119667
118Increased CSF lactate (HP:0002490)1.98684550
119Absent rod-and cone-mediated responses on ERG (HP:0007688)1.98491478
120Concave nail (HP:0001598)1.97437356
121Megalencephaly (HP:0001355)1.97157845
122Craniofacial dystonia (HP:0012179)1.96461632
123Amyotrophic lateral sclerosis (HP:0007354)1.96287872
124Decreased activity of mitochondrial respiratory chain (HP:0008972)1.95384279
125Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.95384279
126Neuronal loss in central nervous system (HP:0002529)1.94020791
127Hepatocellular necrosis (HP:0001404)1.93461598
128Gait imbalance (HP:0002141)1.92973565
129Gait ataxia (HP:0002066)1.92892090
130Psychosis (HP:0000709)1.92675493
131Pendular nystagmus (HP:0012043)1.92555161
132Ketosis (HP:0001946)1.92450100
133Congenital hepatic fibrosis (HP:0002612)1.91102803
134Pointed chin (HP:0000307)1.88934834
135Sclerocornea (HP:0000647)1.88871556
136Decreased electroretinogram (ERG) amplitude (HP:0000654)1.87190463
137Abolished electroretinogram (ERG) (HP:0000550)1.86297855
138Neuroendocrine neoplasm (HP:0100634)1.86169321
139Rapidly progressive (HP:0003678)1.86079761
140Increased muscle lipid content (HP:0009058)1.83689924
141Retinal dysplasia (HP:0007973)1.82813163
142Agitation (HP:0000713)1.82467119
143Cerebellar dysplasia (HP:0007033)1.82092490
144Amelogenesis imperfecta (HP:0000705)1.81706156
145Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.80577414
146Occipital encephalocele (HP:0002085)1.80483239
147Polyuria (HP:0000103)1.80213946
148Abnormality of salivation (HP:0100755)1.78004797
149Hepatic necrosis (HP:0002605)1.77977743
150Anencephaly (HP:0002323)1.76916797
151Tubular atrophy (HP:0000092)1.75459682
152Abnormality of saccadic eye movements (HP:0000570)1.74783835
153Polyphagia (HP:0002591)1.74554047
154Obstructive sleep apnea (HP:0002870)1.74484002
155Akinesia (HP:0002304)1.74401884
156Cerebral hypomyelination (HP:0006808)1.74392679
157Infertility (HP:0000789)1.74163398
158Mesangial abnormality (HP:0001966)1.73681298
159Insomnia (HP:0100785)1.72871582
160Dicarboxylic aciduria (HP:0003215)1.72411234
161Abnormality of dicarboxylic acid metabolism (HP:0010995)1.72411234
162Lipid accumulation in hepatocytes (HP:0006561)1.71740759
163Optic disc pallor (HP:0000543)1.71394580
164Nasal polyposis (HP:0100582)1.71219544
165Limb dystonia (HP:0002451)1.70806788
166Progressive microcephaly (HP:0000253)1.70177935
167Type II lissencephaly (HP:0007260)1.68810475
168Clumsiness (HP:0002312)1.68396499
169Lower limb asymmetry (HP:0100559)1.68296671
170Abnormal EKG (HP:0003115)1.67353006
171Clonus (HP:0002169)1.67259335
172Furrowed tongue (HP:0000221)1.66982983
173Failure to thrive in infancy (HP:0001531)1.66392728
174Deep palmar crease (HP:0006191)1.66254243
175Rigidity (HP:0002063)1.66080749
176Lower limb amyotrophy (HP:0007210)1.64907281
177Specific learning disability (HP:0001328)1.64646142

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.82311317
2NTRK34.64983229
3MAP3K93.97018714
4MAP3K42.92012837
5MINK12.79808472
6FRK2.68565705
7TLK12.62490500
8MAPK152.46000796
9RIPK42.44801151
10DAPK22.41893413
11BCKDK2.38315852
12NTRK12.37673579
13PAK62.36239787
14MAP2K72.34108194
15MARK12.23237873
16KSR22.18000872
17MAP4K21.94757508
18GRK11.92317443
19MAP2K41.91527903
20ADRBK21.90875769
21MAP3K121.90526446
22CASK1.85492007
23NTRK21.82694690
24CAMKK11.81232631
25PRKD31.78953071
26PRKD21.66909251
27DAPK11.61472164
28KSR11.59508815
29SIK21.59312704
30GRK51.59304552
31ARAF1.57202659
32CDK51.55911490
33PNCK1.53662373
34PRPF4B1.52364755
35WNK41.49352029
36PRKCI1.49138378
37INSRR1.48652459
38TNIK1.46283701
39CDK191.43481400
40ZAK1.37605550
41PLK21.36080941
42STK381.35519171
43DYRK21.34923019
44TAOK31.32072564
45PRKCG1.30887277
46PIM21.30823322
47MAP3K131.30807138
48FES1.25618264
49MAPKAPK31.23173175
50GRK61.23080547
51CAMKK21.21571121
52UHMK11.20368240
53MUSK1.18895839
54MAP3K111.17074927
55PKN11.15371343
56MAP3K21.14570028
57RPS6KA21.13383710
58TYRO31.07959066
59CAMK2A1.06014972
60ADRBK11.05966633
61RPS6KA51.03516173
62MAPK131.02195995
63LATS21.01041372
64BMPR20.95297689
65CAMK10.93097279
66CAMK2B0.92877776
67MAP4K10.92836642
68MAP2K20.89982880
69VRK20.89879276
70TNK20.89039464
71MAPKAPK50.88964028
72RAF10.88140611
73CDK180.85796127
74PRKCQ0.84259611
75CDK150.84038778
76AURKA0.83851616
77PHKG20.82808242
78PHKG10.82808242
79CDK140.82793171
80STK110.82658403
81FGFR20.81855431
82TAOK10.81227795
83OXSR10.80536213
84TESK20.80223252
85KDR0.79935939
86RPS6KA60.77307791
87FLT30.76984868
88PTK2B0.76960831
89PRKCH0.76810610
90PINK10.74004127
91KIT0.73942402
92WNK10.73258468
93PRKCD0.73177996
94PAK30.72798294
95CDK11A0.72643937
96NME10.72039903
97IKBKB0.71699523
98RET0.71093536
99IKBKE0.70870254
100SGK4940.69519343
101SGK2230.69519343
102MARK20.68552058
103ALK0.68241274
104CSNK1A10.68102840
105SGK10.66645992
106NUAK10.66617838
107STK160.66424199
108LIMK10.65717322
109BMPR1B0.65178936
110DYRK1A0.64868506
111PDK10.61954766
112LMTK20.61397286
113MAP3K10.61373730
114FGR0.60802190
115CAMK2D0.60158662
116FER0.59704388
117PDPK10.59626833
118HIPK20.59511537
119PRKCA0.59463180
120RPS6KC10.58259105
121RPS6KL10.58259105
122PRKACA0.58110103
123CAMK2G0.57530204
124VRK10.55698506
125AKT30.53322373
126NEK60.52363486
127MAPK100.51689074
128SGK20.49934570
129RPS6KA30.48377483
130PRKCE0.47887663
131CHUK0.47759002
132TIE10.46922937
133PRKCZ0.46372036
134CDC42BPA0.45818696
135CSNK1G30.45731776
136RPS6KB20.45580181
137BRAF0.45567219
138CSNK1G20.44581381
139SGK30.43425102
140MAP3K70.43363314
141MAP3K60.43344100
142MAP2K10.43251521
143FYN0.41695941
144CAMK40.40950074
145CAMK1G0.40364883
146ROCK20.38556960
147SCYL20.36727000
148SIK30.36271318
149DAPK30.35787438
150CSNK1E0.33589017
151RIPK10.31713409
152BCR0.30987136
153ICK0.30368502

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.02910671
2Synaptic vesicle cycle_Homo sapiens_hsa047213.29813034
3Long-term potentiation_Homo sapiens_hsa047202.81907846
4Olfactory transduction_Homo sapiens_hsa047402.79377911
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76683305
6GABAergic synapse_Homo sapiens_hsa047272.74360038
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.69025095
8Glutamatergic synapse_Homo sapiens_hsa047242.65967419
9Circadian entrainment_Homo sapiens_hsa047132.65851372
10Morphine addiction_Homo sapiens_hsa050322.56549147
11Amphetamine addiction_Homo sapiens_hsa050312.51381503
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.32101895
13Salivary secretion_Homo sapiens_hsa049702.25850915
14Dopaminergic synapse_Homo sapiens_hsa047282.16606717
15Insulin secretion_Homo sapiens_hsa049112.07408481
16Parkinsons disease_Homo sapiens_hsa050122.02275643
17Taste transduction_Homo sapiens_hsa047421.99076012
18RNA polymerase_Homo sapiens_hsa030201.98290540
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.94946938
20Gastric acid secretion_Homo sapiens_hsa049711.90703188
21Cholinergic synapse_Homo sapiens_hsa047251.89174490
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.85282641
23Long-term depression_Homo sapiens_hsa047301.84108753
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.78778285
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71132945
26Serotonergic synapse_Homo sapiens_hsa047261.70955923
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.69790704
28Oxytocin signaling pathway_Homo sapiens_hsa049211.68620529
29Renin secretion_Homo sapiens_hsa049241.68344556
30Butanoate metabolism_Homo sapiens_hsa006501.67257822
31Calcium signaling pathway_Homo sapiens_hsa040201.67153754
32Cocaine addiction_Homo sapiens_hsa050301.59933343
33alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.53334650
34Sulfur relay system_Homo sapiens_hsa041221.52070314
35Linoleic acid metabolism_Homo sapiens_hsa005911.51379321
36Collecting duct acid secretion_Homo sapiens_hsa049661.49003690
37GnRH signaling pathway_Homo sapiens_hsa049121.48610840
38Ribosome_Homo sapiens_hsa030101.43589288
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.41950416
40Huntingtons disease_Homo sapiens_hsa050161.41366530
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.41286158
42Gap junction_Homo sapiens_hsa045401.35204072
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.34892699
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33288953
45cAMP signaling pathway_Homo sapiens_hsa040241.33201063
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.27823180
47Primary immunodeficiency_Homo sapiens_hsa053401.22036181
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.18841829
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.18712548
50Estrogen signaling pathway_Homo sapiens_hsa049151.17879943
51Chemical carcinogenesis_Homo sapiens_hsa052041.17720833
52Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16878780
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.14048176
54Cardiac muscle contraction_Homo sapiens_hsa042601.12106889
55Type II diabetes mellitus_Homo sapiens_hsa049301.11220184
56Axon guidance_Homo sapiens_hsa043601.06384719
57Glioma_Homo sapiens_hsa052141.05597787
58cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04302568
59Melanogenesis_Homo sapiens_hsa049161.01793192
60ErbB signaling pathway_Homo sapiens_hsa040121.01167677
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.98830977
62Peroxisome_Homo sapiens_hsa041460.98353692
63Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97965076
64Vascular smooth muscle contraction_Homo sapiens_hsa042700.93287258
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92950458
66Oocyte meiosis_Homo sapiens_hsa041140.92825336
67Vibrio cholerae infection_Homo sapiens_hsa051100.92663210
68Pancreatic secretion_Homo sapiens_hsa049720.90389438
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.90226585
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87313549
71Regulation of autophagy_Homo sapiens_hsa041400.87040114
72beta-Alanine metabolism_Homo sapiens_hsa004100.86013227
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.85262175
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84721162
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.84213138
76Systemic lupus erythematosus_Homo sapiens_hsa053220.81864938
77Thyroid hormone synthesis_Homo sapiens_hsa049180.81287096
78Dorso-ventral axis formation_Homo sapiens_hsa043200.79662801
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79142666
80Phototransduction_Homo sapiens_hsa047440.78300405
81Choline metabolism in cancer_Homo sapiens_hsa052310.75971449
82Autoimmune thyroid disease_Homo sapiens_hsa053200.75846321
83Allograft rejection_Homo sapiens_hsa053300.71385132
84ABC transporters_Homo sapiens_hsa020100.70486192
85MAPK signaling pathway_Homo sapiens_hsa040100.70441191
86Dilated cardiomyopathy_Homo sapiens_hsa054140.69548282
87Ether lipid metabolism_Homo sapiens_hsa005650.69537662
88Asthma_Homo sapiens_hsa053100.69225825
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67518278
90Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67400319
91Tyrosine metabolism_Homo sapiens_hsa003500.66202266
92Graft-versus-host disease_Homo sapiens_hsa053320.65642251
93VEGF signaling pathway_Homo sapiens_hsa043700.65640829
94Purine metabolism_Homo sapiens_hsa002300.65281658
95Tryptophan metabolism_Homo sapiens_hsa003800.63621703
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61932529
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61861517
98Nitrogen metabolism_Homo sapiens_hsa009100.60879175
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.59994316
100Glucagon signaling pathway_Homo sapiens_hsa049220.59821547
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58153747
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.57880087
103Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57482248
104Steroid hormone biosynthesis_Homo sapiens_hsa001400.56593108
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55886861
106Homologous recombination_Homo sapiens_hsa034400.54631903
107Ras signaling pathway_Homo sapiens_hsa040140.54524709
108mTOR signaling pathway_Homo sapiens_hsa041500.53347130
109Arachidonic acid metabolism_Homo sapiens_hsa005900.53199119
110Type I diabetes mellitus_Homo sapiens_hsa049400.52675380
111Inositol phosphate metabolism_Homo sapiens_hsa005620.52544672
112Alcoholism_Homo sapiens_hsa050340.52502454
113Rap1 signaling pathway_Homo sapiens_hsa040150.52060165
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.51565070
115Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50041187
116Alzheimers disease_Homo sapiens_hsa050100.49446424
117Metabolic pathways_Homo sapiens_hsa011000.47642078
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47376220
119Bile secretion_Homo sapiens_hsa049760.46865523
120Circadian rhythm_Homo sapiens_hsa047100.45773302
121Endocytosis_Homo sapiens_hsa041440.42869461
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41546311
123Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41410411
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41339344
125Wnt signaling pathway_Homo sapiens_hsa043100.40839192
126Prion diseases_Homo sapiens_hsa050200.39476952
127Hedgehog signaling pathway_Homo sapiens_hsa043400.39224200
128Non-small cell lung cancer_Homo sapiens_hsa052230.37937867
129Fanconi anemia pathway_Homo sapiens_hsa034600.37021824
130Glutathione metabolism_Homo sapiens_hsa004800.36290497
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36263497
132Pyrimidine metabolism_Homo sapiens_hsa002400.35871236
133Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35205641
134African trypanosomiasis_Homo sapiens_hsa051430.35077649
135Insulin signaling pathway_Homo sapiens_hsa049100.34896829
136Selenocompound metabolism_Homo sapiens_hsa004500.34411260
137Protein export_Homo sapiens_hsa030600.34130448
138Ovarian steroidogenesis_Homo sapiens_hsa049130.33778748
139Glycerolipid metabolism_Homo sapiens_hsa005610.33160472
140Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32858480
141Renal cell carcinoma_Homo sapiens_hsa052110.32427642
142Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31050793
143Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28334930
144Glycerophospholipid metabolism_Homo sapiens_hsa005640.28211135
145Endometrial cancer_Homo sapiens_hsa052130.27111944
146Oxidative phosphorylation_Homo sapiens_hsa001900.25556822
147Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24971555
148Chemokine signaling pathway_Homo sapiens_hsa040620.23689387

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