

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cell killing (GO:0031342) | 7.00012766 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 7.00012766 |
| 3 | tolerance induction (GO:0002507) | 6.73328013 |
| 4 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.62625071 |
| 5 | signal complex assembly (GO:0007172) | 5.58996719 |
| 6 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.35223188 |
| 7 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.24611023 |
| 8 | cellular response to interleukin-15 (GO:0071350) | 5.22696001 |
| 9 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.90518841 |
| 10 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.82319591 |
| 11 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.76404043 |
| 12 | negative thymic T cell selection (GO:0045060) | 4.50879527 |
| 13 | wound healing, spreading of epidermal cells (GO:0035313) | 4.50777756 |
| 14 | leukocyte aggregation (GO:0070486) | 4.48421311 |
| 15 | response to interleukin-15 (GO:0070672) | 4.47104081 |
| 16 | positive regulation of T cell cytokine production (GO:0002726) | 4.37226317 |
| 17 | synapsis (GO:0007129) | 4.30196657 |
| 18 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.28742509 |
| 19 | negative T cell selection (GO:0043383) | 4.27772880 |
| 20 | positive thymic T cell selection (GO:0045059) | 4.22854474 |
| 21 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.18892692 |
| 22 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 4.15762813 |
| 23 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.14822848 |
| 24 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.14822848 |
| 25 | piRNA metabolic process (GO:0034587) | 4.14065282 |
| 26 | neutrophil activation (GO:0042119) | 4.10118044 |
| 27 | activated T cell proliferation (GO:0050798) | 4.09608106 |
| 28 | actin nucleation (GO:0045010) | 4.06457564 |
| 29 | negative regulation of innate immune response (GO:0045824) | 4.04084292 |
| 30 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.91582756 |
| 31 | neutrophil activation involved in immune response (GO:0002283) | 3.89863230 |
| 32 | tumor necrosis factor-mediated signaling pathway (GO:0033209) | 3.77039554 |
| 33 | regulation of gamma-delta T cell activation (GO:0046643) | 3.73108997 |
| 34 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.72454973 |
| 35 | granulocyte activation (GO:0036230) | 3.67094156 |
| 36 | DNA synthesis involved in DNA repair (GO:0000731) | 3.65304523 |
| 37 | mitotic cell cycle arrest (GO:0071850) | 3.63825511 |
| 38 | leukocyte degranulation (GO:0043299) | 3.61287683 |
| 39 | response to muramyl dipeptide (GO:0032495) | 3.60364957 |
| 40 | thymic T cell selection (GO:0045061) | 3.59233114 |
| 41 | peptidyl-threonine dephosphorylation (GO:0035970) | 3.55808435 |
| 42 | wound healing, spreading of cells (GO:0044319) | 3.54841384 |
| 43 | regulation of T cell cytokine production (GO:0002724) | 3.51919519 |
| 44 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.49390878 |
| 45 | male meiosis (GO:0007140) | 3.48644417 |
| 46 | pyrimidine dimer repair (GO:0006290) | 3.48016525 |
| 47 | regulation of DNA damage checkpoint (GO:2000001) | 3.45079372 |
| 48 | mannosylation (GO:0097502) | 3.43536124 |
| 49 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.41289017 |
| 50 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.40194687 |
| 51 | DNA methylation involved in gamete generation (GO:0043046) | 3.36397359 |
| 52 | phospholipid scrambling (GO:0017121) | 3.29653035 |
| 53 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.28387762 |
| 54 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.28045334 |
| 55 | negative regulation of T cell mediated immunity (GO:0002710) | 3.26476951 |
| 56 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.21973849 |
| 57 | T cell receptor signaling pathway (GO:0050852) | 3.18463943 |
| 58 | positive T cell selection (GO:0043368) | 3.17871036 |
| 59 | chromosome organization involved in meiosis (GO:0070192) | 3.12050943 |
| 60 | negative regulation of bone resorption (GO:0045779) | 3.08729384 |
| 61 | positive regulation of T cell mediated immunity (GO:0002711) | 3.06145712 |
| 62 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.05674366 |
| 63 | lymph node development (GO:0048535) | 3.03381672 |
| 64 | regulation of T cell mediated immunity (GO:0002709) | 3.01057524 |
| 65 | regulation of cell killing (GO:0031341) | 3.00863113 |
| 66 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.99918196 |
| 67 | natural killer cell activation (GO:0030101) | 2.98860493 |
| 68 | cellular response to ATP (GO:0071318) | 2.96481401 |
| 69 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.93987193 |
| 70 | cellular defense response (GO:0006968) | 2.92914143 |
| 71 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.91678708 |
| 72 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.90502663 |
| 73 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.88487258 |
| 74 | T cell selection (GO:0045058) | 2.87227036 |
| 75 | meiotic nuclear division (GO:0007126) | 2.86803486 |
| 76 | interferon-gamma secretion (GO:0072643) | 2.85600466 |
| 77 | mast cell activation (GO:0045576) | 2.84499749 |
| 78 | male meiosis I (GO:0007141) | 2.84300797 |
| 79 | adaptation of signaling pathway (GO:0023058) | 2.83631391 |
| 80 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.81412856 |
| 81 | iron-sulfur cluster assembly (GO:0016226) | 2.79426609 |
| 82 | metallo-sulfur cluster assembly (GO:0031163) | 2.79426609 |
| 83 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.78507784 |
| 84 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.78507784 |
| 85 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.78471371 |
| 86 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.75588436 |
| 87 | regulation of mast cell degranulation (GO:0043304) | 2.74744872 |
| 88 | cardiolipin metabolic process (GO:0032048) | 2.74048287 |
| 89 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.73385494 |
| 90 | regulation of necroptotic process (GO:0060544) | 2.72784178 |
| 91 | myeloid cell activation involved in immune response (GO:0002275) | 2.72546948 |
| 92 | T cell migration (GO:0072678) | 2.70265887 |
| 93 | mast cell activation involved in immune response (GO:0002279) | 2.68093868 |
| 94 | mast cell degranulation (GO:0043303) | 2.68093868 |
| 95 | synaptonemal complex assembly (GO:0007130) | 2.65029736 |
| 96 | GPI anchor biosynthetic process (GO:0006506) | 2.64373440 |
| 97 | T cell costimulation (GO:0031295) | 2.62919780 |
| 98 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.62299295 |
| 99 | regulation of lymphocyte mediated immunity (GO:0002706) | 2.60362511 |
| 100 | positive regulation of interleukin-2 production (GO:0032743) | 2.59770693 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.22731119 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.98365553 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.91923839 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.24161860 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.86113903 |
| 6 | MAF_26560356_Chip-Seq_TH1_Human | 2.83288023 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.71650125 |
| 8 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.59349344 |
| 9 | MAF_26560356_Chip-Seq_TH2_Human | 2.59012028 |
| 10 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.58412993 |
| 11 | UTX_26944678_Chip-Seq_JUKART_Human | 2.56005658 |
| 12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.55542648 |
| 13 | MYB_26560356_Chip-Seq_TH2_Human | 2.34995644 |
| 14 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.30636527 |
| 15 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.29007423 |
| 16 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.27068754 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.21912244 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.16435782 |
| 19 | MYC_22102868_ChIP-Seq_BL_Human | 2.12323199 |
| 20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.11063731 |
| 21 | * P68_20966046_ChIP-Seq_HELA_Human | 2.04510144 |
| 22 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.98351040 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.97764968 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.97751551 |
| 25 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.96983108 |
| 26 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.96109674 |
| 27 | MYB_26560356_Chip-Seq_TH1_Human | 1.92765558 |
| 28 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.91253052 |
| 29 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.89958312 |
| 30 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.89111668 |
| 31 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.88243627 |
| 32 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.88144800 |
| 33 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.84728985 |
| 34 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.84424250 |
| 35 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.84371185 |
| 36 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.79219098 |
| 37 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.78293206 |
| 38 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.73235971 |
| 39 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.71495454 |
| 40 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.70997072 |
| 41 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.70033602 |
| 42 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.67941027 |
| 43 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.64944439 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63295094 |
| 45 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.60637567 |
| 46 | * PHF8_20622854_ChIP-Seq_HELA_Human | 1.57227706 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55252117 |
| 48 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.54206770 |
| 49 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.53132654 |
| 50 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.52342102 |
| 51 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.51099796 |
| 52 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.50929476 |
| 53 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.46801163 |
| 54 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.46302600 |
| 55 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.44171805 |
| 56 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.43843799 |
| 57 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.43509950 |
| 58 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.42612971 |
| 59 | GATA3_26560356_Chip-Seq_TH2_Human | 1.41128445 |
| 60 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38998961 |
| 61 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.38954579 |
| 62 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.38431541 |
| 63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37308372 |
| 64 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36959820 |
| 65 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.36843486 |
| 66 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36045264 |
| 67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.35985215 |
| 68 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27901370 |
| 69 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27361957 |
| 70 | P300_27268052_Chip-Seq_Bcells_Human | 1.26687386 |
| 71 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.25512651 |
| 72 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.25203664 |
| 73 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.23438548 |
| 74 | * RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.19787924 |
| 75 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.19449285 |
| 76 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.18156895 |
| 77 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.17835704 |
| 78 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.17554530 |
| 79 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17266862 |
| 80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16262240 |
| 81 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.16093188 |
| 82 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.15814722 |
| 83 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.13317857 |
| 84 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.12925112 |
| 85 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.11841419 |
| 86 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.11140396 |
| 87 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.10114060 |
| 88 | SPI1_23127762_ChIP-Seq_K562_Human | 1.09605320 |
| 89 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.08385429 |
| 90 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.08042531 |
| 91 | * SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.06077098 |
| 92 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.05129549 |
| 93 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.04815794 |
| 94 | GATA1_22025678_ChIP-Seq_K562_Human | 1.03341348 |
| 95 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.00332357 |
| 96 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00256497 |
| 97 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95864189 |
| 98 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94300285 |
| 99 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.94023982 |
| 100 | * ERA_21632823_ChIP-Seq_H3396_Human | 0.92595602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 6.08716846 |
| 2 | MP0005671_abnormal_response_to | 3.99870288 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.97157917 |
| 4 | MP0003436_decreased_susceptibility_to | 3.80408998 |
| 5 | MP0003763_abnormal_thymus_physiology | 3.71338791 |
| 6 | MP0000685_abnormal_immune_system | 2.93050315 |
| 7 | MP0001800_abnormal_humoral_immune | 2.86461571 |
| 8 | MP0005000_abnormal_immune_tolerance | 2.82475656 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.78480947 |
| 10 | MP0002723_abnormal_immune_serum | 2.63336063 |
| 11 | MP0001819_abnormal_immune_cell | 2.43872391 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.38039961 |
| 13 | MP0002452_abnormal_antigen_presenting | 2.34478940 |
| 14 | MP0001986_abnormal_taste_sensitivity | 2.21435562 |
| 15 | MP0002398_abnormal_bone_marrow | 2.15437049 |
| 16 | MP0001790_abnormal_immune_system | 2.10924176 |
| 17 | MP0005387_immune_system_phenotype | 2.10924176 |
| 18 | MP0009333_abnormal_splenocyte_physiolog | 2.05956813 |
| 19 | MP0002419_abnormal_innate_immunity | 2.04796170 |
| 20 | MP0005025_abnormal_response_to | 2.04470306 |
| 21 | MP0003828_pulmonary_edema | 2.04087819 |
| 22 | MP0000465_gastrointestinal_hemorrhage | 2.02766653 |
| 23 | MP0001919_abnormal_reproductive_system | 1.96941884 |
| 24 | MP0000703_abnormal_thymus_morphology | 1.90797775 |
| 25 | MP0000716_abnormal_immune_system | 1.90244873 |
| 26 | MP0002877_abnormal_melanocyte_morpholog | 1.90127796 |
| 27 | MP0002405_respiratory_system_inflammati | 1.86851807 |
| 28 | MP0001533_abnormal_skeleton_physiology | 1.85848967 |
| 29 | MP0002722_abnormal_immune_system | 1.83234536 |
| 30 | MP0001661_extended_life_span | 1.83195279 |
| 31 | MP0000689_abnormal_spleen_morphology | 1.79433638 |
| 32 | MP0005075_abnormal_melanosome_morpholog | 1.72814244 |
| 33 | MP0002148_abnormal_hypersensitivity_rea | 1.72087201 |
| 34 | MP0000015_abnormal_ear_pigmentation | 1.67617566 |
| 35 | MP0002396_abnormal_hematopoietic_system | 1.63095997 |
| 36 | MP0003300_gastrointestinal_ulcer | 1.58506390 |
| 37 | MP0002429_abnormal_blood_cell | 1.58247975 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.57667571 |
| 39 | MP0006082_CNS_inflammation | 1.50938379 |
| 40 | MP0009785_altered_susceptibility_to | 1.49446837 |
| 41 | MP0002166_altered_tumor_susceptibility | 1.48557948 |
| 42 | MP0004947_skin_inflammation | 1.48233797 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.45014169 |
| 44 | MP0005389_reproductive_system_phenotype | 1.42267586 |
| 45 | MP0002009_preneoplasia | 1.42018340 |
| 46 | MP0004185_abnormal_adipocyte_glucose | 1.40163107 |
| 47 | MP0004381_abnormal_hair_follicle | 1.39246381 |
| 48 | MP0004130_abnormal_muscle_cell | 1.38773232 |
| 49 | MP0004043_abnormal_pH_regulation | 1.25614695 |
| 50 | MP0002102_abnormal_ear_morphology | 1.21840160 |
| 51 | MP0002933_joint_inflammation | 1.20456192 |
| 52 | MP0003866_abnormal_defecation | 1.20359421 |
| 53 | MP0005058_abnormal_lysosome_morphology | 1.20250464 |
| 54 | MP0010155_abnormal_intestine_physiology | 1.20081174 |
| 55 | MP0005257_abnormal_intraocular_pressure | 1.15462452 |
| 56 | MP0005174_abnormal_tail_pigmentation | 1.14560096 |
| 57 | MP0005171_absent_coat_pigmentation | 1.14047051 |
| 58 | MP0005310_abnormal_salivary_gland | 1.12892405 |
| 59 | MP0008057_abnormal_DNA_replication | 1.08986444 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.08265273 |
| 61 | MP0003878_abnormal_ear_physiology | 1.08265273 |
| 62 | MP0005076_abnormal_cell_differentiation | 1.04508605 |
| 63 | MP0008469_abnormal_protein_level | 1.01813553 |
| 64 | MP0003656_abnormal_erythrocyte_physiolo | 1.00265230 |
| 65 | MP0000858_altered_metastatic_potential | 0.99426974 |
| 66 | MP0000003_abnormal_adipose_tissue | 0.95234784 |
| 67 | MP0003943_abnormal_hepatobiliary_system | 0.95072490 |
| 68 | MP0000013_abnormal_adipose_tissue | 0.92312818 |
| 69 | MP0002006_tumorigenesis | 0.90065781 |
| 70 | MP0004264_abnormal_extraembryonic_tissu | 0.86848249 |
| 71 | MP0002928_abnormal_bile_duct | 0.86606849 |
| 72 | MP0005670_abnormal_white_adipose | 0.80774084 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.80711731 |
| 74 | MP0004147_increased_porphyrin_level | 0.80417930 |
| 75 | MP0001851_eye_inflammation | 0.79355130 |
| 76 | MP0001968_abnormal_touch/_nociception | 0.79318121 |
| 77 | MP0002019_abnormal_tumor_incidence | 0.78632735 |
| 78 | MP0009278_abnormal_bone_marrow | 0.78273864 |
| 79 | MP0003880_abnormal_central_pattern | 0.75174418 |
| 80 | MP0002998_abnormal_bone_remodeling | 0.73069683 |
| 81 | MP0003786_premature_aging | 0.70698407 |
| 82 | MP0003795_abnormal_bone_structure | 0.69568292 |
| 83 | MP0001765_abnormal_ion_homeostasis | 0.69550499 |
| 84 | MP0001873_stomach_inflammation | 0.69503490 |
| 85 | MP0002160_abnormal_reproductive_system | 0.68756266 |
| 86 | MP0005397_hematopoietic_system_phenotyp | 0.66963824 |
| 87 | MP0001545_abnormal_hematopoietic_system | 0.66963824 |
| 88 | MP0005390_skeleton_phenotype | 0.65411348 |
| 89 | MP0001929_abnormal_gametogenesis | 0.64973223 |
| 90 | MP0003787_abnormal_imprinting | 0.63959914 |
| 91 | MP0006072_abnormal_retinal_apoptosis | 0.63428967 |
| 92 | MP0009764_decreased_sensitivity_to | 0.63379616 |
| 93 | MP0003303_peritoneal_inflammation | 0.63333669 |
| 94 | MP0008995_early_reproductive_senescence | 0.58679710 |
| 95 | MP0003448_altered_tumor_morphology | 0.57731436 |
| 96 | MP0001119_abnormal_female_reproductive | 0.57333808 |
| 97 | MP0009765_abnormal_xenobiotic_induced | 0.57325348 |
| 98 | MP0002210_abnormal_sex_determination | 0.56913678 |
| 99 | MP0003329_amyloid_beta_deposits | 0.56880124 |
| 100 | MP0003111_abnormal_nucleus_morphology | 0.55692835 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 4.80867793 |
| 2 | Anteriorly placed anus (HP:0001545) | 4.71668031 |
| 3 | IgG deficiency (HP:0004315) | 4.63366190 |
| 4 | Eczematoid dermatitis (HP:0000976) | 4.37387314 |
| 5 | T lymphocytopenia (HP:0005403) | 4.35955648 |
| 6 | Abnormality of T cells (HP:0002843) | 3.90260288 |
| 7 | Abnormality of T cell number (HP:0011839) | 3.81459584 |
| 8 | Increased IgM level (HP:0003496) | 3.51830422 |
| 9 | IgM deficiency (HP:0002850) | 3.44536110 |
| 10 | Myositis (HP:0100614) | 3.44021851 |
| 11 | Abnormality of macrophages (HP:0004311) | 3.43811462 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 3.42230247 |
| 13 | Pustule (HP:0200039) | 3.36502368 |
| 14 | Granulocytopenia (HP:0001913) | 3.31438619 |
| 15 | Abnormality of T cell physiology (HP:0011840) | 3.28129953 |
| 16 | Gastrointestinal stroma tumor (HP:0100723) | 3.22428737 |
| 17 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.10433233 |
| 18 | Retrobulbar optic neuritis (HP:0100654) | 3.08614269 |
| 19 | Optic neuritis (HP:0100653) | 3.08614269 |
| 20 | Encephalitis (HP:0002383) | 3.06434567 |
| 21 | Stomach cancer (HP:0012126) | 3.05421609 |
| 22 | Orchitis (HP:0100796) | 3.02809112 |
| 23 | Abnormality of eosinophils (HP:0001879) | 3.01688034 |
| 24 | Recurrent bronchitis (HP:0002837) | 2.99132808 |
| 25 | Episodic fever (HP:0001954) | 2.97566923 |
| 26 | Vasculitis (HP:0002633) | 2.85740623 |
| 27 | Joint swelling (HP:0001386) | 2.82788358 |
| 28 | Poikiloderma (HP:0001029) | 2.81892395 |
| 29 | B lymphocytopenia (HP:0010976) | 2.80977373 |
| 30 | Severe combined immunodeficiency (HP:0004430) | 2.80462315 |
| 31 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.75359068 |
| 32 | Abnormality of B cell number (HP:0010975) | 2.74744560 |
| 33 | Spontaneous hematomas (HP:0007420) | 2.74585901 |
| 34 | Recurrent abscess formation (HP:0002722) | 2.71968315 |
| 35 | Eosinophilia (HP:0001880) | 2.71474711 |
| 36 | Recurrent bacterial skin infections (HP:0005406) | 2.66481087 |
| 37 | Recurrent fungal infections (HP:0002841) | 2.63470532 |
| 38 | Mediastinal lymphadenopathy (HP:0100721) | 2.61956429 |
| 39 | Meningitis (HP:0001287) | 2.59847240 |
| 40 | Chromsome breakage (HP:0040012) | 2.58273095 |
| 41 | Elevated alkaline phosphatase (HP:0003155) | 2.56031515 |
| 42 | Abnormality of alkaline phosphatase activity (HP:0004379) | 2.54960484 |
| 43 | Combined immunodeficiency (HP:0005387) | 2.49957118 |
| 44 | Recurrent viral infections (HP:0004429) | 2.42681639 |
| 45 | Anorexia (HP:0002039) | 2.42266930 |
| 46 | Hemorrhage of the eye (HP:0011885) | 2.41226900 |
| 47 | Prostate neoplasm (HP:0100787) | 2.38406208 |
| 48 | Facial diplegia (HP:0001349) | 2.35051763 |
| 49 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.34367143 |
| 50 | Obstructive lung disease (HP:0006536) | 2.33978070 |
| 51 | Chronic obstructive pulmonary disease (HP:0006510) | 2.33978070 |
| 52 | Abnormality of cochlea (HP:0000375) | 2.32831498 |
| 53 | Pulmonary infiltrates (HP:0002113) | 2.31264377 |
| 54 | Keratoconjunctivitis (HP:0001096) | 2.27443411 |
| 55 | Increased IgE level (HP:0003212) | 2.26930414 |
| 56 | Large eyes (HP:0001090) | 2.25817098 |
| 57 | Panhypogammaglobulinemia (HP:0003139) | 2.25305204 |
| 58 | Premature graying of hair (HP:0002216) | 2.25211209 |
| 59 | Lymphopenia (HP:0001888) | 2.23238018 |
| 60 | Premature loss of primary teeth (HP:0006323) | 2.22159271 |
| 61 | Prolonged bleeding time (HP:0003010) | 2.21349914 |
| 62 | Absent speech (HP:0001344) | 2.17971383 |
| 63 | Epistaxis (HP:0000421) | 2.17298814 |
| 64 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.16638768 |
| 65 | Keratoconjunctivitis sicca (HP:0001097) | 2.16337106 |
| 66 | Choroideremia (HP:0001139) | 2.15909643 |
| 67 | Nasal polyposis (HP:0100582) | 2.15801637 |
| 68 | Abnormality of carpal bone ossification (HP:0006257) | 2.15441581 |
| 69 | Broad face (HP:0000283) | 2.15088332 |
| 70 | Bulbar palsy (HP:0001283) | 2.13781386 |
| 71 | IgA deficiency (HP:0002720) | 2.13050305 |
| 72 | Tented upper lip vermilion (HP:0010804) | 2.11881218 |
| 73 | Leukocytosis (HP:0001974) | 2.10359022 |
| 74 | Inflammation of the large intestine (HP:0002037) | 2.09917959 |
| 75 | Alveolar cell carcinoma (HP:0006519) | 2.09389692 |
| 76 | Recurrent sinusitis (HP:0011108) | 2.08470792 |
| 77 | Gastrointestinal inflammation (HP:0004386) | 2.08189307 |
| 78 | Hemoptysis (HP:0002105) | 2.07853577 |
| 79 | Abnormality of the periventricular white matter (HP:0002518) | 2.07553598 |
| 80 | Verrucae (HP:0200043) | 2.07237058 |
| 81 | Papilloma (HP:0012740) | 2.07237058 |
| 82 | Joint hemorrhage (HP:0005261) | 2.06833564 |
| 83 | Abnormality of the prostate (HP:0008775) | 2.05897889 |
| 84 | Basal cell carcinoma (HP:0002671) | 2.04501208 |
| 85 | Easy fatigability (HP:0003388) | 2.04051175 |
| 86 | Attenuation of retinal blood vessels (HP:0007843) | 2.03312999 |
| 87 | Hypertriglyceridemia (HP:0002155) | 2.02906498 |
| 88 | Petechiae (HP:0000967) | 2.02323618 |
| 89 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.01798607 |
| 90 | Chest pain (HP:0100749) | 1.98933144 |
| 91 | Urticaria (HP:0001025) | 1.98421272 |
| 92 | Keratitis (HP:0000491) | 1.98399365 |
| 93 | Neutropenia (HP:0001875) | 1.97476048 |
| 94 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.96491284 |
| 95 | Emphysema (HP:0002097) | 1.93627361 |
| 96 | Absent thumb (HP:0009777) | 1.93001326 |
| 97 | Recurrent cutaneous fungal infections (HP:0011370) | 1.91611149 |
| 98 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.91611149 |
| 99 | Long palpebral fissure (HP:0000637) | 1.89333832 |
| 100 | Squamous cell carcinoma (HP:0002860) | 1.88452534 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 5.83321587 |
| 2 | GRK6 | 4.60592062 |
| 3 | MUSK | 4.44640852 |
| 4 | MAP4K1 | 4.13394540 |
| 5 | MAP2K2 | 3.62562557 |
| 6 | PLK4 | 3.32088980 |
| 7 | CDK8 | 3.05919688 |
| 8 | TXK | 2.48271142 |
| 9 | ZAP70 | 2.06643783 |
| 10 | TESK2 | 1.98776411 |
| 11 | SIK3 | 1.97362493 |
| 12 | MAP3K14 | 1.93498914 |
| 13 | RIPK4 | 1.83325468 |
| 14 | SIK2 | 1.79873421 |
| 15 | CSK | 1.68180307 |
| 16 | BLK | 1.59035357 |
| 17 | FGR | 1.51876880 |
| 18 | JAK1 | 1.49308000 |
| 19 | FES | 1.49274853 |
| 20 | MARK3 | 1.45528245 |
| 21 | MAPK15 | 1.41677997 |
| 22 | MST4 | 1.41471711 |
| 23 | MATK | 1.34094399 |
| 24 | PRKD2 | 1.33785307 |
| 25 | TNK2 | 1.26985094 |
| 26 | SIK1 | 1.26596296 |
| 27 | CSF1R | 1.25794210 |
| 28 | MAP2K1 | 1.25097699 |
| 29 | BTK | 1.23801114 |
| 30 | JAK3 | 1.18448030 |
| 31 | STK10 | 1.18350363 |
| 32 | MAP3K11 | 1.16157280 |
| 33 | KDR | 1.15741803 |
| 34 | ITK | 1.15282534 |
| 35 | PRPF4B | 1.15066000 |
| 36 | IKBKE | 1.10616612 |
| 37 | TBK1 | 1.09102981 |
| 38 | LCK | 1.08148550 |
| 39 | PIM1 | 1.07526926 |
| 40 | CDK4 | 1.06883670 |
| 41 | SYK | 1.04353988 |
| 42 | PTK2B | 1.01139108 |
| 43 | TRIB3 | 1.00735055 |
| 44 | IRAK3 | 1.00456623 |
| 45 | IKBKB | 0.98146932 |
| 46 | TYK2 | 0.96081072 |
| 47 | MAP3K7 | 0.92017902 |
| 48 | HCK | 0.90974220 |
| 49 | KIT | 0.88513159 |
| 50 | MAP2K3 | 0.86659032 |
| 51 | ERN1 | 0.85416428 |
| 52 | CDK12 | 0.82505638 |
| 53 | NUAK1 | 0.78360563 |
| 54 | BMX | 0.78265691 |
| 55 | LYN | 0.77490301 |
| 56 | CDK3 | 0.76773056 |
| 57 | TLK1 | 0.75904600 |
| 58 | DYRK3 | 0.71881858 |
| 59 | MAPK11 | 0.65719079 |
| 60 | RPS6KB2 | 0.62787074 |
| 61 | PDK1 | 0.61865953 |
| 62 | ADRBK2 | 0.61757984 |
| 63 | PRKCQ | 0.61733032 |
| 64 | PLK2 | 0.61108630 |
| 65 | MAPK12 | 0.59329911 |
| 66 | IRAK4 | 0.54321566 |
| 67 | CDK9 | 0.53628625 |
| 68 | EPHB1 | 0.51741044 |
| 69 | PDPK1 | 0.48683928 |
| 70 | CDK6 | 0.48020577 |
| 71 | FGFR4 | 0.47102144 |
| 72 | RPS6KA6 | 0.46709424 |
| 73 | RPS6KL1 | 0.44698373 |
| 74 | RPS6KC1 | 0.44698373 |
| 75 | MAP3K1 | 0.42740487 |
| 76 | MAP3K3 | 0.39421803 |
| 77 | RAF1 | 0.38953712 |
| 78 | MAP3K10 | 0.38038375 |
| 79 | RPS6KA2 | 0.37971049 |
| 80 | DYRK1B | 0.34704463 |
| 81 | RET | 0.31880768 |
| 82 | PDGFRB | 0.31586606 |
| 83 | NEK2 | 0.31561339 |
| 84 | ICK | 0.31205840 |
| 85 | MARK2 | 0.29209428 |
| 86 | PRKD1 | 0.28041994 |
| 87 | DAPK2 | 0.27740909 |
| 88 | MAPK7 | 0.27559228 |
| 89 | TAOK2 | 0.26652581 |
| 90 | ABL1 | 0.25981487 |
| 91 | PINK1 | 0.25927193 |
| 92 | MAP3K12 | 0.25513825 |
| 93 | PRKCD | 0.24631218 |
| 94 | JAK2 | 0.22886513 |
| 95 | LRRK2 | 0.21722647 |
| 96 | STK38 | 0.21700898 |
| 97 | PRKCH | 0.21581018 |
| 98 | INSR | 0.21433895 |
| 99 | FYN | 0.20755702 |
| 100 | MAPKAPK2 | 0.20745933 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.35653542 |
| 2 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.15513226 |
| 3 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 3.12710663 |
| 4 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.86975744 |
| 5 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.79387239 |
| 6 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.72560721 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.67128828 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.62702868 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.37697778 |
| 10 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.20674047 |
| 11 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.14401147 |
| 12 | Allograft rejection_Homo sapiens_hsa05330 | 2.07314594 |
| 13 | Leishmaniasis_Homo sapiens_hsa05140 | 2.07233453 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.98188519 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.95659126 |
| 16 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.90150968 |
| 17 | Measles_Homo sapiens_hsa05162 | 1.77574951 |
| 18 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.75193273 |
| 19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.71676870 |
| 20 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.70645530 |
| 21 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.62951613 |
| 22 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.49390424 |
| 23 | Other glycan degradation_Homo sapiens_hsa00511 | 1.47947304 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.46581407 |
| 25 | Apoptosis_Homo sapiens_hsa04210 | 1.46450504 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.46178329 |
| 27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.42016668 |
| 28 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.34818801 |
| 29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.30740153 |
| 30 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.29263947 |
| 31 | Shigellosis_Homo sapiens_hsa05131 | 1.26620547 |
| 32 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.25666282 |
| 33 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.20067248 |
| 34 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.19453743 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.16536040 |
| 36 | Malaria_Homo sapiens_hsa05144 | 1.16275560 |
| 37 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.11090268 |
| 38 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.06979308 |
| 39 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.06693655 |
| 40 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.06410664 |
| 41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.03988588 |
| 42 | Tuberculosis_Homo sapiens_hsa05152 | 0.97919256 |
| 43 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.97250216 |
| 44 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.93749391 |
| 45 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.92598407 |
| 46 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.87950183 |
| 47 | Endocytosis_Homo sapiens_hsa04144 | 0.85657758 |
| 48 | Legionellosis_Homo sapiens_hsa05134 | 0.84781093 |
| 49 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.83993945 |
| 50 | Sulfur relay system_Homo sapiens_hsa04122 | 0.82823677 |
| 51 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.81950898 |
| 52 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.80004256 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.77532533 |
| 54 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.77385976 |
| 55 | Lysosome_Homo sapiens_hsa04142 | 0.71842035 |
| 56 | Hepatitis B_Homo sapiens_hsa05161 | 0.71725853 |
| 57 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.70880306 |
| 58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.68732387 |
| 59 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.67849826 |
| 60 | Asthma_Homo sapiens_hsa05310 | 0.67165460 |
| 61 | Hepatitis C_Homo sapiens_hsa05160 | 0.64404313 |
| 62 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.62323746 |
| 63 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.62309033 |
| 64 | Platelet activation_Homo sapiens_hsa04611 | 0.61990315 |
| 65 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.61785024 |
| 66 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.61289222 |
| 67 | Influenza A_Homo sapiens_hsa05164 | 0.60946426 |
| 68 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.58457706 |
| 69 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.57264762 |
| 70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.55199885 |
| 71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.54774818 |
| 72 | Thyroid cancer_Homo sapiens_hsa05216 | 0.54628190 |
| 73 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54296022 |
| 74 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.54220006 |
| 75 | Salmonella infection_Homo sapiens_hsa05132 | 0.53327767 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52649013 |
| 77 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.50642530 |
| 78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50343631 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50043437 |
| 80 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.49196585 |
| 81 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47106814 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46472742 |
| 83 | Homologous recombination_Homo sapiens_hsa03440 | 0.44792679 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44782726 |
| 85 | Pertussis_Homo sapiens_hsa05133 | 0.44552827 |
| 86 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40291173 |
| 87 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.38499243 |
| 88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36433650 |
| 89 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.35993951 |
| 90 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.33917296 |
| 91 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.32848649 |
| 92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.31269787 |
| 93 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.30935882 |
| 94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.30689409 |
| 95 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.30524467 |
| 96 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.27436837 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26413033 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.25895483 |
| 99 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.24799599 |
| 100 | Cell cycle_Homo sapiens_hsa04110 | 0.23668763 |

