

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | L-serine metabolic process (GO:0006563) | 6.21244780 |
| 2 | ribosome assembly (GO:0042255) | 5.19312879 |
| 3 | establishment of integrated proviral latency (GO:0075713) | 5.12343095 |
| 4 | IMP biosynthetic process (GO:0006188) | 4.76394786 |
| 5 | IMP metabolic process (GO:0046040) | 4.57530956 |
| 6 | proteasome assembly (GO:0043248) | 4.54632768 |
| 7 | cullin deneddylation (GO:0010388) | 4.47146071 |
| 8 | protein localization to kinetochore (GO:0034501) | 4.42155371 |
| 9 | chromatin remodeling at centromere (GO:0031055) | 4.35122672 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.33988464 |
| 11 | DNA double-strand break processing (GO:0000729) | 4.31197451 |
| 12 | CENP-A containing nucleosome assembly (GO:0034080) | 4.23776371 |
| 13 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.21798028 |
| 14 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.21798028 |
| 15 | establishment of viral latency (GO:0019043) | 4.18816617 |
| 16 | DNA replication checkpoint (GO:0000076) | 4.18520992 |
| 17 | protein deneddylation (GO:0000338) | 4.16186353 |
| 18 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.11708450 |
| 19 | mitotic metaphase plate congression (GO:0007080) | 3.99978873 |
| 20 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.98928632 |
| 21 | serine family amino acid biosynthetic process (GO:0009070) | 3.97085494 |
| 22 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.93946012 |
| 23 | tRNA aminoacylation for protein translation (GO:0006418) | 3.89698159 |
| 24 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.88528025 |
| 25 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.88528025 |
| 26 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.86359795 |
| 27 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.86359795 |
| 28 | amino acid activation (GO:0043038) | 3.84534762 |
| 29 | tRNA aminoacylation (GO:0043039) | 3.84534762 |
| 30 | histone exchange (GO:0043486) | 3.83898482 |
| 31 | purine nucleobase biosynthetic process (GO:0009113) | 3.83404705 |
| 32 | negative regulation of DNA recombination (GO:0045910) | 3.82518128 |
| 33 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.80138937 |
| 34 | protein neddylation (GO:0045116) | 3.77314440 |
| 35 | DNA strand elongation (GO:0022616) | 3.74373321 |
| 36 | regulation of helicase activity (GO:0051095) | 3.73772479 |
| 37 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.72122783 |
| 38 | negative regulation of ligase activity (GO:0051352) | 3.72122783 |
| 39 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.70585957 |
| 40 | DNA replication-independent nucleosome organization (GO:0034724) | 3.64482267 |
| 41 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.64482267 |
| 42 | lysine metabolic process (GO:0006553) | 3.61585031 |
| 43 | lysine catabolic process (GO:0006554) | 3.61585031 |
| 44 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.61380021 |
| 45 | non-recombinational repair (GO:0000726) | 3.61022015 |
| 46 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.61022015 |
| 47 | DNA damage response, detection of DNA damage (GO:0042769) | 3.59780693 |
| 48 | spindle checkpoint (GO:0031577) | 3.54506090 |
| 49 | nucleobase biosynthetic process (GO:0046112) | 3.47574730 |
| 50 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.46195671 |
| 51 | metaphase plate congression (GO:0051310) | 3.46159633 |
| 52 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.45244287 |
| 53 | negative regulation of sister chromatid segregation (GO:0033046) | 3.45244287 |
| 54 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.45244287 |
| 55 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.45244287 |
| 56 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.45244287 |
| 57 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.43617163 |
| 58 | negative regulation of chromosome segregation (GO:0051985) | 3.40953279 |
| 59 | mitotic spindle checkpoint (GO:0071174) | 3.40104899 |
| 60 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.37263298 |
| 61 | DNA ligation (GO:0006266) | 3.36959048 |
| 62 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.35978108 |
| 63 | isotype switching (GO:0045190) | 3.35978108 |
| 64 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.35978108 |
| 65 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.33329075 |
| 66 | regulation of centriole replication (GO:0046599) | 3.33154897 |
| 67 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.31332578 |
| 68 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.27630525 |
| 69 | protein localization to chromosome, centromeric region (GO:0071459) | 3.25320778 |
| 70 | spliceosomal snRNP assembly (GO:0000387) | 3.24737456 |
| 71 | formation of translation preinitiation complex (GO:0001731) | 3.15365539 |
| 72 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.13443448 |
| 73 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.13443448 |
| 74 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.13443448 |
| 75 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.13192560 |
| 76 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.13192560 |
| 77 | protein complex localization (GO:0031503) | 3.11556535 |
| 78 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.09114129 |
| 79 | mitotic spindle assembly checkpoint (GO:0007094) | 3.07112258 |
| 80 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.07079370 |
| 81 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.07079370 |
| 82 | histone H2A acetylation (GO:0043968) | 3.06938499 |
| 83 | spindle assembly checkpoint (GO:0071173) | 3.04593470 |
| 84 | RNA-dependent DNA replication (GO:0006278) | 3.04425871 |
| 85 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.04071170 |
| 86 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.04071170 |
| 87 | telomere maintenance via telomerase (GO:0007004) | 3.03644138 |
| 88 | lactate metabolic process (GO:0006089) | 3.01413056 |
| 89 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.00842309 |
| 90 | rRNA modification (GO:0000154) | 3.00640568 |
| 91 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.99916583 |
| 92 | telomere maintenance via telomere lengthening (GO:0010833) | 2.99574157 |
| 93 | regulation of sister chromatid segregation (GO:0033045) | 2.97682776 |
| 94 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.97682776 |
| 95 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.97682776 |
| 96 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.96901329 |
| 97 | somatic diversification of immunoglobulins (GO:0016445) | 2.96885708 |
| 98 | establishment of chromosome localization (GO:0051303) | 2.92683051 |
| 99 | mitotic nuclear envelope disassembly (GO:0007077) | 2.92682324 |
| 100 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.92166164 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.49910315 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.79301413 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.25937815 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66170386 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.58574179 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.39631188 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.34497477 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.16631617 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.08135739 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.89230964 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.85824229 |
| 12 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.62026562 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.53903463 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.53588753 |
| 15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.52848475 |
| 16 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.48891084 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.40639043 |
| 18 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.37330329 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.35617795 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.30989954 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.22584040 |
| 22 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.19491948 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.19080109 |
| 24 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.16428910 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.14797748 |
| 26 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.12777091 |
| 27 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.12218015 |
| 28 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.99154058 |
| 29 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.95224015 |
| 30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.93822398 |
| 31 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.92583310 |
| 32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89468602 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81117207 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.80896845 |
| 35 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.79426717 |
| 36 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.77521042 |
| 37 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.74118809 |
| 38 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.72720488 |
| 39 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.72305753 |
| 40 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.71132902 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.68810626 |
| 42 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64677324 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.61544309 |
| 44 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.59974884 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.59918217 |
| 46 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59455327 |
| 47 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.59353108 |
| 48 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.55377800 |
| 49 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.55359434 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.54023663 |
| 51 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.50164337 |
| 52 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.48080524 |
| 53 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.46753694 |
| 54 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45468068 |
| 55 | EWS_26573619_Chip-Seq_HEK293_Human | 1.44329248 |
| 56 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.44056977 |
| 57 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.43246020 |
| 58 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.42552410 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42228889 |
| 60 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40049328 |
| 61 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.38311203 |
| 62 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34597580 |
| 63 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.33622718 |
| 64 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.32782233 |
| 65 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.31571631 |
| 66 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.30752772 |
| 67 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.28536399 |
| 68 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.27409941 |
| 69 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.15622775 |
| 70 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.12746466 |
| 71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.12276131 |
| 72 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.11740308 |
| 73 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.10668303 |
| 74 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.09168062 |
| 75 | FUS_26573619_Chip-Seq_HEK293_Human | 1.08471177 |
| 76 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.03384651 |
| 77 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03251655 |
| 78 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.01281429 |
| 79 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.00673744 |
| 80 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.00673744 |
| 81 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.00673744 |
| 82 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00435987 |
| 83 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.98918180 |
| 84 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.96908951 |
| 85 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.96341150 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.92237201 |
| 87 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.91129353 |
| 88 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.90897547 |
| 89 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.89914078 |
| 90 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88255436 |
| 91 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87513103 |
| 92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.87448202 |
| 93 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86626755 |
| 94 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.86352307 |
| 95 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85039490 |
| 96 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.83967023 |
| 97 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82321930 |
| 98 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.79510981 |
| 99 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.76611859 |
| 100 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.76156735 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 4.65484000 |
| 2 | MP0008877_abnormal_DNA_methylation | 4.65023989 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.57408670 |
| 4 | MP0003693_abnormal_embryo_hatching | 4.43982156 |
| 5 | MP0003111_abnormal_nucleus_morphology | 3.66579917 |
| 6 | MP0003941_abnormal_skin_development | 3.37384913 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 3.32457793 |
| 8 | MP0008007_abnormal_cellular_replicative | 3.06445808 |
| 9 | MP0008932_abnormal_embryonic_tissue | 2.85816367 |
| 10 | MP0003077_abnormal_cell_cycle | 2.82738543 |
| 11 | MP0002254_reproductive_system_inflammat | 2.82459753 |
| 12 | MP0003718_maternal_effect | 2.40100370 |
| 13 | MP0004147_increased_porphyrin_level | 2.29122679 |
| 14 | MP0003787_abnormal_imprinting | 2.13464851 |
| 15 | MP0003122_maternal_imprinting | 2.05045365 |
| 16 | MP0002102_abnormal_ear_morphology | 2.01785595 |
| 17 | MP0001529_abnormal_vocalization | 2.00296437 |
| 18 | MP0003786_premature_aging | 1.98108737 |
| 19 | MP0001730_embryonic_growth_arrest | 1.95278926 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.88755463 |
| 21 | MP0009697_abnormal_copulation | 1.82097649 |
| 22 | MP0008057_abnormal_DNA_replication | 1.80553976 |
| 23 | MP0003121_genomic_imprinting | 1.78606608 |
| 24 | MP0009672_abnormal_birth_weight | 1.68644896 |
| 25 | MP0001188_hyperpigmentation | 1.64740659 |
| 26 | MP0003119_abnormal_digestive_system | 1.64085913 |
| 27 | MP0001293_anophthalmia | 1.63619527 |
| 28 | MP0002736_abnormal_nociception_after | 1.59926379 |
| 29 | MP0006292_abnormal_olfactory_placode | 1.58659625 |
| 30 | MP0006035_abnormal_mitochondrial_morpho | 1.54051157 |
| 31 | MP0003806_abnormal_nucleotide_metabolis | 1.47486064 |
| 32 | MP0010352_gastrointestinal_tract_polyps | 1.46679012 |
| 33 | MP0000350_abnormal_cell_proliferation | 1.42079143 |
| 34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.41864240 |
| 35 | MP0003937_abnormal_limbs/digits/tail_de | 1.33514604 |
| 36 | MP0003011_delayed_dark_adaptation | 1.33142067 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.32261923 |
| 38 | MP0003890_abnormal_embryonic-extraembry | 1.32090888 |
| 39 | MP0002751_abnormal_autonomic_nervous | 1.28989073 |
| 40 | MP0003315_abnormal_perineum_morphology | 1.28172801 |
| 41 | MP0002084_abnormal_developmental_patter | 1.26784501 |
| 42 | MP0005499_abnormal_olfactory_system | 1.26462340 |
| 43 | MP0005394_taste/olfaction_phenotype | 1.26462340 |
| 44 | MP0004133_heterotaxia | 1.26384460 |
| 45 | MP0006276_abnormal_autonomic_nervous | 1.24399720 |
| 46 | MP0003136_yellow_coat_color | 1.24082420 |
| 47 | MP0003186_abnormal_redox_activity | 1.22063759 |
| 48 | MP0003221_abnormal_cardiomyocyte_apopto | 1.20574817 |
| 49 | MP0002085_abnormal_embryonic_tissue | 1.19519570 |
| 50 | MP0001177_atelectasis | 1.15725815 |
| 51 | MP0001984_abnormal_olfaction | 1.14540306 |
| 52 | MP0005253_abnormal_eye_physiology | 1.13764921 |
| 53 | MP0001697_abnormal_embryo_size | 1.13759373 |
| 54 | MP0001672_abnormal_embryogenesis/_devel | 1.12240952 |
| 55 | MP0005380_embryogenesis_phenotype | 1.12240952 |
| 56 | MP0002090_abnormal_vision | 1.12093895 |
| 57 | MP0002080_prenatal_lethality | 1.08821451 |
| 58 | MP0004197_abnormal_fetal_growth/weight/ | 1.03412842 |
| 59 | MP0005084_abnormal_gallbladder_morpholo | 1.03054806 |
| 60 | MP0000358_abnormal_cell_content/ | 0.99859650 |
| 61 | MP0001286_abnormal_eye_development | 0.99173831 |
| 62 | MP0002938_white_spotting | 0.99002816 |
| 63 | MP0009703_decreased_birth_body | 0.97182883 |
| 64 | MP0000313_abnormal_cell_death | 0.94548542 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 0.93295009 |
| 66 | MP0005395_other_phenotype | 0.92478487 |
| 67 | MP0001929_abnormal_gametogenesis | 0.91194606 |
| 68 | MP0003880_abnormal_central_pattern | 0.90052976 |
| 69 | MP0003984_embryonic_growth_retardation | 0.84472785 |
| 70 | MP0004782_abnormal_surfactant_physiolog | 0.83262864 |
| 71 | MP0002210_abnormal_sex_determination | 0.82273937 |
| 72 | MP0000653_abnormal_sex_gland | 0.80963622 |
| 73 | MP0002088_abnormal_embryonic_growth/wei | 0.80718179 |
| 74 | MP0001485_abnormal_pinna_reflex | 0.79422363 |
| 75 | MP0001764_abnormal_homeostasis | 0.79184034 |
| 76 | MP0000579_abnormal_nail_morphology | 0.78743088 |
| 77 | MP0001145_abnormal_male_reproductive | 0.77217314 |
| 78 | MP0000647_abnormal_sebaceous_gland | 0.76118668 |
| 79 | MP0005551_abnormal_eye_electrophysiolog | 0.76044027 |
| 80 | MP0000049_abnormal_middle_ear | 0.71243199 |
| 81 | MP0002111_abnormal_tail_morphology | 0.70984742 |
| 82 | MP0000516_abnormal_urinary_system | 0.70478399 |
| 83 | MP0005367_renal/urinary_system_phenotyp | 0.70478399 |
| 84 | MP0005391_vision/eye_phenotype | 0.69935422 |
| 85 | MP0001119_abnormal_female_reproductive | 0.69727836 |
| 86 | MP0002086_abnormal_extraembryonic_tissu | 0.69264082 |
| 87 | MP0002233_abnormal_nose_morphology | 0.68883059 |
| 88 | MP0002638_abnormal_pupillary_reflex | 0.65682739 |
| 89 | MP0003123_paternal_imprinting | 0.65334656 |
| 90 | MP0002697_abnormal_eye_size | 0.64780545 |
| 91 | MP0003698_abnormal_male_reproductive | 0.62351403 |
| 92 | MP0008872_abnormal_physiological_respon | 0.61806633 |
| 93 | MP0005248_abnormal_Harderian_gland | 0.61635852 |
| 94 | MP0002277_abnormal_respiratory_mucosa | 0.57780432 |
| 95 | MP0002653_abnormal_ependyma_morphology | 0.57416659 |
| 96 | MP0003861_abnormal_nervous_system | 0.56856264 |
| 97 | MP0008770_decreased_survivor_rate | 0.56715296 |
| 98 | MP0001299_abnormal_eye_distance/ | 0.54491505 |
| 99 | MP0002161_abnormal_fertility/fecundity | 0.52790270 |
| 100 | MP0010307_abnormal_tumor_latency | 0.52653420 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 5.09356878 |
| 2 | Colon cancer (HP:0003003) | 4.12799095 |
| 3 | Abnormality of glycine metabolism (HP:0010895) | 3.64540410 |
| 4 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.64540410 |
| 5 | Abnormality of glycolysis (HP:0004366) | 3.54365501 |
| 6 | Abnormality of serum amino acid levels (HP:0003112) | 3.51934919 |
| 7 | Ependymoma (HP:0002888) | 3.32113968 |
| 8 | Increased serum pyruvate (HP:0003542) | 3.29290561 |
| 9 | Hyperglycinemia (HP:0002154) | 3.26932403 |
| 10 | Spastic diplegia (HP:0001264) | 3.13914955 |
| 11 | Multiple enchondromatosis (HP:0005701) | 3.02356331 |
| 12 | Microvesicular hepatic steatosis (HP:0001414) | 2.99571933 |
| 13 | Medulloblastoma (HP:0002885) | 2.96622800 |
| 14 | Postnatal microcephaly (HP:0005484) | 2.92282644 |
| 15 | Meckel diverticulum (HP:0002245) | 2.87437561 |
| 16 | Abnormal gallbladder physiology (HP:0012438) | 2.86867211 |
| 17 | Cholecystitis (HP:0001082) | 2.86867211 |
| 18 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.79256948 |
| 19 | Shoulder girdle muscle weakness (HP:0003547) | 2.74212282 |
| 20 | Neoplasm of the adrenal gland (HP:0100631) | 2.73002445 |
| 21 | Birth length less than 3rd percentile (HP:0003561) | 2.72972075 |
| 22 | Acute encephalopathy (HP:0006846) | 2.72856171 |
| 23 | Abnormality of the ileum (HP:0001549) | 2.71902915 |
| 24 | Acute necrotizing encephalopathy (HP:0006965) | 2.70239459 |
| 25 | Rhabdomyosarcoma (HP:0002859) | 2.68448839 |
| 26 | Hyperglycinuria (HP:0003108) | 2.64718698 |
| 27 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.63713192 |
| 28 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.60663371 |
| 29 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.60663371 |
| 30 | Cortical dysplasia (HP:0002539) | 2.59801081 |
| 31 | Abnormality of methionine metabolism (HP:0010901) | 2.57975295 |
| 32 | Increased hepatocellular lipid droplets (HP:0006565) | 2.51428090 |
| 33 | Chromsome breakage (HP:0040012) | 2.48886064 |
| 34 | Abnormality of the preputium (HP:0100587) | 2.47212197 |
| 35 | Glioma (HP:0009733) | 2.46506088 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.46395395 |
| 37 | Agnosia (HP:0010524) | 2.45281000 |
| 38 | Stenosis of the external auditory canal (HP:0000402) | 2.41505443 |
| 39 | Pelvic girdle muscle weakness (HP:0003749) | 2.37062681 |
| 40 | Abnormality of the astrocytes (HP:0100707) | 2.37001695 |
| 41 | Astrocytoma (HP:0009592) | 2.37001695 |
| 42 | Abnormal lung lobation (HP:0002101) | 2.36105730 |
| 43 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.34114062 |
| 44 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.33932987 |
| 45 | Methylmalonic acidemia (HP:0002912) | 2.30233457 |
| 46 | Abnormality of the pons (HP:0007361) | 2.29114674 |
| 47 | Abnormality of chromosome stability (HP:0003220) | 2.28113489 |
| 48 | Cerebral hypomyelination (HP:0006808) | 2.24519695 |
| 49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.24267342 |
| 50 | Embryonal renal neoplasm (HP:0011794) | 2.23284094 |
| 51 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.22302623 |
| 52 | Broad foot (HP:0001769) | 2.19825159 |
| 53 | Hypoplasia of the pons (HP:0012110) | 2.19461331 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.18311589 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 2.18311589 |
| 56 | Hyperalaninemia (HP:0003348) | 2.18311589 |
| 57 | Neoplasm of the colon (HP:0100273) | 2.15927283 |
| 58 | Cerebral edema (HP:0002181) | 2.14613717 |
| 59 | Increased CSF lactate (HP:0002490) | 2.14172670 |
| 60 | Abnormal hair whorl (HP:0010721) | 2.12610936 |
| 61 | Mitochondrial inheritance (HP:0001427) | 2.11830525 |
| 62 | Progressive macrocephaly (HP:0004481) | 2.11085155 |
| 63 | Small intestinal stenosis (HP:0012848) | 2.10836910 |
| 64 | Duodenal stenosis (HP:0100867) | 2.10836910 |
| 65 | Congenital primary aphakia (HP:0007707) | 2.10742139 |
| 66 | Type I transferrin isoform profile (HP:0003642) | 2.09174059 |
| 67 | Horseshoe kidney (HP:0000085) | 2.07165994 |
| 68 | Leukodystrophy (HP:0002415) | 2.06808296 |
| 69 | Bile duct proliferation (HP:0001408) | 2.06195560 |
| 70 | Abnormal biliary tract physiology (HP:0012439) | 2.06195560 |
| 71 | Abnormality of the metopic suture (HP:0005556) | 2.04835430 |
| 72 | Medial flaring of the eyebrow (HP:0010747) | 2.02219684 |
| 73 | Prominent metopic ridge (HP:0005487) | 2.01651168 |
| 74 | Sloping forehead (HP:0000340) | 2.01573790 |
| 75 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.01029145 |
| 76 | Gait imbalance (HP:0002141) | 2.00464181 |
| 77 | Sensory axonal neuropathy (HP:0003390) | 1.96607509 |
| 78 | Nephrogenic diabetes insipidus (HP:0009806) | 1.95886777 |
| 79 | Increased serum lactate (HP:0002151) | 1.93539178 |
| 80 | Biliary tract neoplasm (HP:0100574) | 1.86659484 |
| 81 | Exercise-induced muscle cramps (HP:0003710) | 1.85199412 |
| 82 | Lactic acidosis (HP:0003128) | 1.84382782 |
| 83 | Methylmalonic aciduria (HP:0012120) | 1.83360816 |
| 84 | Optic nerve coloboma (HP:0000588) | 1.82654068 |
| 85 | Dandy-Walker malformation (HP:0001305) | 1.81645168 |
| 86 | Abnormality of the duodenum (HP:0002246) | 1.80568489 |
| 87 | Sensorimotor neuropathy (HP:0007141) | 1.79368343 |
| 88 | Neoplasm of the small intestine (HP:0100833) | 1.79166847 |
| 89 | Absent radius (HP:0003974) | 1.76101679 |
| 90 | Ovarian neoplasm (HP:0100615) | 1.75948617 |
| 91 | Large hands (HP:0001176) | 1.75301370 |
| 92 | Genital tract atresia (HP:0001827) | 1.74733404 |
| 93 | Pendular nystagmus (HP:0012043) | 1.73268229 |
| 94 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.71523690 |
| 95 | Vaginal atresia (HP:0000148) | 1.71192312 |
| 96 | Pancreatic cysts (HP:0001737) | 1.70999732 |
| 97 | Abnormality of the anterior horn cell (HP:0006802) | 1.69665170 |
| 98 | Degeneration of anterior horn cells (HP:0002398) | 1.69665170 |
| 99 | Aplasia involving forearm bones (HP:0009822) | 1.69113775 |
| 100 | Absent forearm bone (HP:0003953) | 1.69113775 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.15026972 |
| 2 | BUB1 | 4.49003735 |
| 3 | SRPK1 | 3.91001353 |
| 4 | TRIM28 | 3.03342915 |
| 5 | CDC7 | 2.94835555 |
| 6 | MKNK2 | 2.88174743 |
| 7 | TTK | 2.87845615 |
| 8 | TNIK | 2.87134864 |
| 9 | PLK3 | 2.78161465 |
| 10 | MKNK1 | 2.76701810 |
| 11 | NEK1 | 2.69849469 |
| 12 | ZAK | 2.61289202 |
| 13 | PBK | 2.50016098 |
| 14 | VRK2 | 2.31294579 |
| 15 | BCR | 2.07994184 |
| 16 | EIF2AK1 | 2.07366802 |
| 17 | WNK3 | 2.02647099 |
| 18 | MST4 | 1.86270207 |
| 19 | TAF1 | 1.73317581 |
| 20 | RPS6KA4 | 1.66983621 |
| 21 | PLK4 | 1.59311059 |
| 22 | NUAK1 | 1.59115798 |
| 23 | PLK1 | 1.58370385 |
| 24 | BCKDK | 1.50348067 |
| 25 | STK16 | 1.46818909 |
| 26 | VRK1 | 1.45705555 |
| 27 | EIF2AK3 | 1.44731871 |
| 28 | WEE1 | 1.43291283 |
| 29 | CSNK1G1 | 1.29888350 |
| 30 | ALK | 1.25641858 |
| 31 | CSNK1G3 | 1.19623898 |
| 32 | PASK | 1.16175584 |
| 33 | NME1 | 1.09665210 |
| 34 | MAP3K4 | 1.08489696 |
| 35 | CSNK1G2 | 1.06858316 |
| 36 | BRSK2 | 1.04170629 |
| 37 | ATR | 1.03983665 |
| 38 | CSNK1A1L | 0.99809663 |
| 39 | MAP4K2 | 0.98625707 |
| 40 | STK38L | 0.97686181 |
| 41 | DAPK1 | 0.93365616 |
| 42 | TIE1 | 0.92635383 |
| 43 | BRSK1 | 0.91961335 |
| 44 | EIF2AK2 | 0.85259119 |
| 45 | PLK2 | 0.84693286 |
| 46 | AURKB | 0.82976936 |
| 47 | BMPR1B | 0.79422512 |
| 48 | SIK3 | 0.73298336 |
| 49 | CDK9 | 0.72669127 |
| 50 | EPHA4 | 0.72467409 |
| 51 | DYRK2 | 0.71225021 |
| 52 | CHEK1 | 0.70431906 |
| 53 | CDK19 | 0.70408324 |
| 54 | CHEK2 | 0.67982092 |
| 55 | ATM | 0.67084969 |
| 56 | ERBB4 | 0.62092319 |
| 57 | ERBB3 | 0.60886095 |
| 58 | GRK1 | 0.60731983 |
| 59 | TGFBR1 | 0.60121519 |
| 60 | PDK2 | 0.58840506 |
| 61 | DYRK3 | 0.58815060 |
| 62 | PAK4 | 0.58520343 |
| 63 | CDK6 | 0.55206833 |
| 64 | RPS6KA5 | 0.53307206 |
| 65 | TLK1 | 0.53238815 |
| 66 | CSNK2A1 | 0.52771952 |
| 67 | FGFR1 | 0.50464378 |
| 68 | CDK7 | 0.50039334 |
| 69 | CSNK2A2 | 0.49321151 |
| 70 | MINK1 | 0.48314767 |
| 71 | STK4 | 0.47608439 |
| 72 | ACVR1B | 0.45367809 |
| 73 | CSNK1E | 0.43084458 |
| 74 | LIMK1 | 0.42899432 |
| 75 | PRKDC | 0.40413586 |
| 76 | AURKA | 0.40114533 |
| 77 | OXSR1 | 0.39802944 |
| 78 | CDK1 | 0.37454458 |
| 79 | CDK18 | 0.36764041 |
| 80 | MAP2K7 | 0.36300848 |
| 81 | CASK | 0.36179653 |
| 82 | CDK14 | 0.34523613 |
| 83 | CDK2 | 0.34406099 |
| 84 | PRKCG | 0.33638713 |
| 85 | UHMK1 | 0.33604815 |
| 86 | STK10 | 0.32620769 |
| 87 | MAP3K10 | 0.32612082 |
| 88 | STK24 | 0.31590240 |
| 89 | CSNK1A1 | 0.30527560 |
| 90 | FLT3 | 0.30227805 |
| 91 | CDK3 | 0.30009962 |
| 92 | MAP3K8 | 0.27851161 |
| 93 | CDK15 | 0.27095555 |
| 94 | PRKCI | 0.26516266 |
| 95 | CDK8 | 0.26196363 |
| 96 | BRD4 | 0.26101002 |
| 97 | CDK11A | 0.24038501 |
| 98 | CSNK1D | 0.22811522 |
| 99 | INSRR | 0.21925192 |
| 100 | NLK | 0.21583970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.94984047 |
| 2 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 3.31882569 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.19421868 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.12144498 |
| 5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.06747125 |
| 6 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.04429186 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.84321351 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.39588605 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.38744691 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.36418794 |
| 11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.32856232 |
| 12 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.21184595 |
| 13 | Base excision repair_Homo sapiens_hsa03410 | 2.18409517 |
| 14 | Spliceosome_Homo sapiens_hsa03040 | 2.13165773 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.11843431 |
| 16 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.11064420 |
| 17 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.09704352 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 2.09583881 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.04967665 |
| 20 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 2.02986490 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.99748316 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.90867665 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.81556169 |
| 24 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.76033641 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.73055361 |
| 26 | Carbon metabolism_Homo sapiens_hsa01200 | 1.71087886 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.66444432 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.64830082 |
| 29 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.63291088 |
| 30 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.60268530 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.56210916 |
| 32 | Cell cycle_Homo sapiens_hsa04110 | 1.53594254 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.47651563 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.44473786 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.41971278 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30525090 |
| 37 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.13471829 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.13397953 |
| 39 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.09626831 |
| 40 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.09582911 |
| 41 | Parkinsons disease_Homo sapiens_hsa05012 | 1.04000573 |
| 42 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.02667957 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.98120061 |
| 44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.94764187 |
| 45 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91953697 |
| 46 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.91672501 |
| 47 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.90408651 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84769422 |
| 49 | Huntingtons disease_Homo sapiens_hsa05016 | 0.81977936 |
| 50 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.81583532 |
| 51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.79883541 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.75676491 |
| 53 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.72848583 |
| 54 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.72088979 |
| 55 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.71157914 |
| 56 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.70837284 |
| 57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69954452 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67340995 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64860708 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.61553945 |
| 61 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.60010881 |
| 62 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59454728 |
| 63 | Phototransduction_Homo sapiens_hsa04744 | 0.58194492 |
| 64 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.52515081 |
| 65 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.47283175 |
| 66 | Alzheimers disease_Homo sapiens_hsa05010 | 0.43352229 |
| 67 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.42280472 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41933679 |
| 69 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.39987076 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.38778204 |
| 71 | Nicotine addiction_Homo sapiens_hsa05033 | 0.37010404 |
| 72 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.36413189 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34402809 |
| 74 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33307203 |
| 75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32522368 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.31186850 |
| 77 | Galactose metabolism_Homo sapiens_hsa00052 | 0.30515758 |
| 78 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.29688538 |
| 79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.29258173 |
| 80 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.28665900 |
| 81 | Lysine degradation_Homo sapiens_hsa00310 | 0.27268993 |
| 82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.27102365 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26540598 |
| 84 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.25895697 |
| 85 | Tight junction_Homo sapiens_hsa04530 | 0.24806695 |
| 86 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.23993293 |
| 87 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23952304 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.22669822 |
| 89 | Ribosome_Homo sapiens_hsa03010 | 0.22457419 |
| 90 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.17553632 |
| 91 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.17447609 |
| 92 | Retinol metabolism_Homo sapiens_hsa00830 | 0.14311618 |
| 93 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.13475424 |
| 94 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.13372837 |
| 95 | Legionellosis_Homo sapiens_hsa05134 | 0.11049505 |
| 96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.10441969 |
| 97 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.08693171 |
| 98 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.08620530 |
| 99 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.07907419 |
| 100 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.07756399 |

