Rank | Gene Set | Z-score |
---|---|---|
1 | androgen biosynthetic process (GO:0006702) | 9.14058426 |
2 | * multi-multicellular organism process (GO:0044706) | 8.32981529 |
3 | androgen metabolic process (GO:0008209) | 8.10780765 |
4 | positive regulation of growth hormone secretion (GO:0060124) | 7.31356910 |
5 | * multi-organism reproductive process (GO:0044703) | 7.24749262 |
6 | glucocorticoid metabolic process (GO:0008211) | 6.47157477 |
7 | hormone biosynthetic process (GO:0042446) | 5.92105851 |
8 | myoblast fusion (GO:0007520) | 5.59810912 |
9 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 5.53118235 |
10 | response to gonadotropin (GO:0034698) | 5.34689212 |
11 | regulation of growth hormone secretion (GO:0060123) | 5.34375875 |
12 | vascular endothelial growth factor signaling pathway (GO:0038084) | 5.31372472 |
13 | syncytium formation (GO:0006949) | 5.12217185 |
14 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 5.08711584 |
15 | syncytium formation by plasma membrane fusion (GO:0000768) | 4.97312206 |
16 | endocrine hormone secretion (GO:0060986) | 4.95182788 |
17 | collecting duct development (GO:0072044) | 4.82296615 |
18 | positive regulation of protein kinase C signaling (GO:0090037) | 4.77110808 |
19 | lymphangiogenesis (GO:0001946) | 4.71872663 |
20 | sphingoid metabolic process (GO:0046519) | 4.61026829 |
21 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.59297985 |
22 | negative regulation of activin receptor signaling pathway (GO:0032926) | 4.56743050 |
23 | vitamin transmembrane transport (GO:0035461) | 4.43803074 |
24 | lymph vessel development (GO:0001945) | 4.21744764 |
25 | bone morphogenesis (GO:0060349) | 4.07218400 |
26 | sprouting angiogenesis (GO:0002040) | 4.03714188 |
27 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 3.93848013 |
28 | type B pancreatic cell proliferation (GO:0044342) | 3.63750909 |
29 | parturition (GO:0007567) | 3.47444164 |
30 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 3.43418329 |
31 | bone trabecula formation (GO:0060346) | 3.38412334 |
32 | basement membrane organization (GO:0071711) | 3.38242955 |
33 | eyelid development in camera-type eye (GO:0061029) | 3.36134466 |
34 | collagen fibril organization (GO:0030199) | 3.28266279 |
35 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.05606589 |
36 | myelin maintenance (GO:0043217) | 3.04796600 |
37 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.02964026 |
38 | protein heterotrimerization (GO:0070208) | 3.00169588 |
39 | estrogen biosynthetic process (GO:0006703) | 26.1299851 |
40 | blood vessel maturation (GO:0001955) | 2.96859514 |
41 | extracellular regulation of signal transduction (GO:1900115) | 2.96538720 |
42 | extracellular negative regulation of signal transduction (GO:1900116) | 2.96538720 |
43 | cellular response to vitamin (GO:0071295) | 2.94561119 |
44 | skin morphogenesis (GO:0043589) | 2.91150005 |
45 | JAK-STAT cascade (GO:0007259) | 2.88838397 |
46 | T-helper 1 type immune response (GO:0042088) | 2.85816144 |
47 | iron ion import (GO:0097286) | 2.85657628 |
48 | protein neddylation (GO:0045116) | 2.85405212 |
49 | cellular hormone metabolic process (GO:0034754) | 2.83154832 |
50 | negative regulation of cell-matrix adhesion (GO:0001953) | 2.80824342 |
51 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.79884450 |
52 | C21-steroid hormone biosynthetic process (GO:0006700) | 2.78252949 |
53 | progesterone metabolic process (GO:0042448) | 2.75484767 |
54 | positive regulation of cartilage development (GO:0061036) | 2.75478651 |
55 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.75374583 |
56 | mitotic cytokinesis (GO:0000281) | 2.73846206 |
57 | regulation of G0 to G1 transition (GO:0070316) | 2.73559854 |
58 | adhesion of symbiont to host (GO:0044406) | 2.71569914 |
59 | endodermal cell differentiation (GO:0035987) | 2.70876702 |
60 | regulation of endocrine process (GO:0044060) | 2.68346062 |
61 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.67027141 |
62 | adhesion of symbiont to host cell (GO:0044650) | 2.66226999 |
63 | virion attachment to host cell (GO:0019062) | 2.66226999 |
64 | sphingosine metabolic process (GO:0006670) | 2.64029450 |
65 | polarized epithelial cell differentiation (GO:0030859) | 2.61048949 |
66 | cytoskeleton-dependent cytokinesis (GO:0061640) | 2.59370518 |
67 | blood vessel morphogenesis (GO:0048514) | 2.58595620 |
68 | positive regulation of insulin receptor signaling pathway (GO:0046628) | 2.57127803 |
69 | interkinetic nuclear migration (GO:0022027) | 2.53818127 |
70 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 2.50511014 |
71 | extracellular matrix assembly (GO:0085029) | 2.42544268 |
72 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.40401596 |
73 | wound healing, spreading of epidermal cells (GO:0035313) | 2.39476742 |
74 | hyaluronan catabolic process (GO:0030214) | 2.35570559 |
75 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.35422750 |
76 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.34645904 |
77 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.34189536 |
78 | regulation of protein kinase C signaling (GO:0090036) | 2.31977436 |
79 | fibroblast migration (GO:0010761) | 2.27757679 |
80 | diol metabolic process (GO:0034311) | 2.27497343 |
81 | steroid biosynthetic process (GO:0006694) | 2.25584947 |
82 | positive regulation of p38MAPK cascade (GO:1900745) | 2.23280197 |
83 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 2.22294796 |
84 | negative regulation of myoblast differentiation (GO:0045662) | 2.20776023 |
85 | adherens junction assembly (GO:0034333) | 2.20602533 |
86 | import into cell (GO:0098657) | 2.20544299 |
87 | keratinocyte development (GO:0003334) | 2.20272724 |
88 | cell migration involved in heart development (GO:0060973) | 2.19949111 |
89 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.19198754 |
90 | negative regulation of BMP signaling pathway (GO:0030514) | 2.18924348 |
91 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.18124353 |
92 | smooth muscle tissue development (GO:0048745) | 2.15662577 |
93 | cellular response to vitamin D (GO:0071305) | 2.14984325 |
94 | negative regulation of osteoblast proliferation (GO:0033689) | 2.13359208 |
95 | response to follicle-stimulating hormone (GO:0032354) | 12.5391654 |
96 | regulation of gonadotropin secretion (GO:0032276) | 11.7698563 |
97 | * female pregnancy (GO:0007565) | 11.5407722 |
98 | estrogen metabolic process (GO:0008210) | 11.4171050 |
99 | glucocorticoid biosynthetic process (GO:0006704) | 10.8864328 |
100 | prostate gland growth (GO:0060736) | 10.3100631 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.96236832 |
2 | * EGR1_19032775_ChIP-ChIP_M12_Human | 3.02210219 |
3 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.92589542 |
4 | BRD4_25478319_ChIP-Seq_HGPS_Human | 2.66004501 |
5 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.59469570 |
6 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.57732418 |
7 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.53142567 |
8 | AHR_22903824_ChIP-Seq_MCF-7_Human | 2.37039907 |
9 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.30153020 |
10 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.22815055 |
11 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 2.18283394 |
12 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.15999857 |
13 | * TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 2.15467587 |
14 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 2.13577650 |
15 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.12889104 |
16 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.12340094 |
17 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.09040013 |
18 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 10.2036787 |
19 | CJUN_26792858_Chip-Seq_BT549_Human | 1.98254511 |
20 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.92040951 |
21 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.87500759 |
22 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.74634254 |
23 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.70179164 |
24 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.69201148 |
25 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.64867246 |
26 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.64439167 |
27 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.61706507 |
28 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.61706507 |
29 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.60821248 |
30 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.58322907 |
31 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.54988582 |
32 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.52403541 |
33 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.51722791 |
34 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.49651018 |
35 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.49651018 |
36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.46466104 |
37 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.45552635 |
38 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.44454114 |
39 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.41588810 |
40 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.39833135 |
41 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.35514519 |
42 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.33873811 |
43 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.33223317 |
44 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.32890899 |
45 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.28010410 |
46 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.27147295 |
47 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.27147295 |
48 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.25145551 |
49 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.25037487 |
50 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.24950089 |
51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.24323725 |
52 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.23941188 |
53 | RXR_22108803_ChIP-Seq_LS180_Human | 1.22921125 |
54 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.20494286 |
55 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.20040192 |
56 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.16453981 |
57 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.15850104 |
58 | * TP63_23658742_ChIP-Seq_EP156T_Human | 1.15494117 |
59 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.14239606 |
60 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12373956 |
61 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.09663457 |
62 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.08422371 |
63 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.07061057 |
64 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.06611031 |
65 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.06211215 |
66 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.03983540 |
67 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.03120135 |
68 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.03085704 |
69 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.00775618 |
70 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.00353407 |
71 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00334773 |
72 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.00326528 |
73 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.99878368 |
74 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.99247659 |
75 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98673045 |
76 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.96660161 |
77 | TP53_16413492_ChIP-PET_HCT116_Human | 0.96135892 |
78 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.95974172 |
79 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95199561 |
80 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.91796268 |
81 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.90277864 |
82 | JUN_21703547_ChIP-Seq_K562_Human | 0.88887041 |
83 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.87376740 |
84 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.87376740 |
85 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.86524644 |
86 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.85965527 |
87 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.85030229 |
88 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.84783985 |
89 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.84431591 |
90 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.83899580 |
91 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.83504570 |
92 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.81611436 |
93 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.81189311 |
94 | P300_19829295_ChIP-Seq_ESCs_Human | 0.81086990 |
95 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.77993956 |
96 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.77721665 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.77497270 |
98 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.77370763 |
99 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.77349170 |
100 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.76092306 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009697_abnormal_copulation | 9.17264802 |
2 | MP0002163_abnormal_gland_morphology | 5.37802883 |
3 | MP0008438_abnormal_cutaneous_collagen | 4.74592362 |
4 | MP0010368_abnormal_lymphatic_system | 3.99476045 |
5 | MP0005379_endocrine/exocrine_gland_phen | 3.82314932 |
6 | MP0006276_abnormal_autonomic_nervous | 3.75843559 |
7 | MP0006054_spinal_hemorrhage | 3.49548992 |
8 | MP0000013_abnormal_adipose_tissue | 3.22015180 |
9 | MP0003941_abnormal_skin_development | 3.00896021 |
10 | MP0005647_abnormal_sex_gland | 2.93715924 |
11 | MP0003705_abnormal_hypodermis_morpholog | 2.84526037 |
12 | MP0001958_emphysema | 2.70643536 |
13 | MP0001919_abnormal_reproductive_system | 2.66316469 |
14 | MP0005503_abnormal_tendon_morphology | 2.61493184 |
15 | MP0004272_abnormal_basement_membrane | 2.57263485 |
16 | MP0005275_abnormal_skin_tensile | 2.38926234 |
17 | MP0000003_abnormal_adipose_tissue | 2.29792136 |
18 | MP0003950_abnormal_plasma_membrane | 2.13068033 |
19 | MP0003959_abnormal_lean_body | 2.06992328 |
20 | MP0003279_aneurysm | 2.01970128 |
21 | MP0005023_abnormal_wound_healing | 1.93316264 |
22 | MP0009384_cardiac_valve_regurgitation | 1.91166202 |
23 | MP0001440_abnormal_grooming_behavior | 1.87899268 |
24 | MP0005389_reproductive_system_phenotype | 1.59909665 |
25 | MP0003566_abnormal_cell_adhesion | 1.57787205 |
26 | MP0004019_abnormal_vitamin_homeostasis | 1.57371789 |
27 | MP0002876_abnormal_thyroid_physiology | 1.54814326 |
28 | MP0002295_abnormal_pulmonary_circulatio | 1.53015485 |
29 | MP0005257_abnormal_intraocular_pressure | 1.51177024 |
30 | MP0001879_abnormal_lymphatic_vessel | 1.49129734 |
31 | MP0009115_abnormal_fat_cell | 1.45896969 |
32 | MP0002998_abnormal_bone_remodeling | 1.44934060 |
33 | MP0001666_abnormal_nutrient_absorption | 1.33831826 |
34 | MP0006138_congestive_heart_failure | 1.33394306 |
35 | MP0003936_abnormal_reproductive_system | 1.33259540 |
36 | MP0000613_abnormal_salivary_gland | 1.30885169 |
37 | MP0002971_abnormal_brown_adipose | 1.27373685 |
38 | MP0010352_gastrointestinal_tract_polyps | 1.27031238 |
39 | MP0000639_abnormal_adrenal_gland | 1.27012514 |
40 | MP0009780_abnormal_chondrocyte_physiolo | 1.21355305 |
41 | MP0003091_abnormal_cell_migration | 1.20141144 |
42 | MP0001542_abnormal_bone_strength | 1.15529651 |
43 | MP0001243_abnormal_dermal_layer | 1.09380359 |
44 | MP0001756_abnormal_urination | 1.08474933 |
45 | MP0000767_abnormal_smooth_muscle | 1.07194064 |
46 | MP0002108_abnormal_muscle_morphology | 1.00794245 |
47 | MP0002128_abnormal_blood_circulation | 1.00446967 |
48 | MP0005375_adipose_tissue_phenotype | 0.99573798 |
49 | MP0009703_decreased_birth_body | 0.99266662 |
50 | MP0000647_abnormal_sebaceous_gland | 0.98253893 |
51 | MP0002060_abnormal_skin_morphology | 0.96098021 |
52 | MP0002075_abnormal_coat/hair_pigmentati | 0.94976772 |
53 | MP0010386_abnormal_urinary_bladder | 0.94454274 |
54 | MP0003385_abnormal_body_wall | 0.91985018 |
55 | MP0003453_abnormal_keratinocyte_physiol | 0.89708993 |
56 | MP0010329_abnormal_lipoprotein_level | 0.88357218 |
57 | MP0004947_skin_inflammation | 0.87591760 |
58 | MP0000681_abnormal_thyroid_gland | 0.85892564 |
59 | MP0003191_abnormal_cellular_cholesterol | 0.85474559 |
60 | MP0000230_abnormal_systemic_arterial | 0.84835077 |
61 | MP0003795_abnormal_bone_structure | 0.83165991 |
62 | MP0000759_abnormal_skeletal_muscle | 0.80894712 |
63 | MP0000534_abnormal_ureter_morphology | 0.80750030 |
64 | MP0002653_abnormal_ependyma_morphology | 0.80622255 |
65 | MP0001915_intracranial_hemorrhage | 0.77528976 |
66 | MP0005508_abnormal_skeleton_morphology | 0.74990231 |
67 | MP0002896_abnormal_bone_mineralization | 0.69761678 |
68 | MP0001299_abnormal_eye_distance/ | 0.69018964 |
69 | MP0005595_abnormal_vascular_smooth | 0.67348930 |
70 | MP0004085_abnormal_heartbeat | 0.65657225 |
71 | MP0000751_myopathy | 0.65189653 |
72 | MP0001186_pigmentation_phenotype | 0.64425086 |
73 | MP0005334_abnormal_fat_pad | 0.62816943 |
74 | MP0005164_abnormal_response_to | 0.61414748 |
75 | MP0004858_abnormal_nervous_system | 0.61141097 |
76 | MP0001348_abnormal_lacrimal_gland | 0.57458654 |
77 | MP0003828_pulmonary_edema | 0.56137557 |
78 | MP0001340_abnormal_eyelid_morphology | 0.55818852 |
79 | MP0002972_abnormal_cardiac_muscle | 0.55650707 |
80 | MP0005623_abnormal_meninges_morphology | 0.55131788 |
81 | MP0000685_abnormal_immune_system | 0.53618811 |
82 | MP0003448_altered_tumor_morphology | 0.50626805 |
83 | MP0002086_abnormal_extraembryonic_tissu | 0.50144480 |
84 | MP0001614_abnormal_blood_vessel | 0.49361344 |
85 | MP0002113_abnormal_skeleton_development | 0.49067108 |
86 | MP0003115_abnormal_respiratory_system | 0.48228726 |
87 | MP0002909_abnormal_adrenal_gland | 0.47351592 |
88 | MP0005165_increased_susceptibility_to | 0.46237586 |
89 | MP0009250_abnormal_appendicular_skeleto | 0.44937839 |
90 | MP0002557_abnormal_social/conspecific_i | 0.43735084 |
91 | MP0002115_abnormal_skeleton_extremities | 0.41753778 |
92 | MP0000367_abnormal_coat/_hair | 0.41587596 |
93 | MP0002925_abnormal_cardiovascular_devel | 0.41123313 |
94 | MP0000266_abnormal_heart_morphology | 0.40538067 |
95 | MP0004510_myositis | 0.39306469 |
96 | MP0001765_abnormal_ion_homeostasis | 0.38867243 |
97 | MP0004883_abnormal_blood_vessel | 0.38374261 |
98 | MP0005319_abnormal_enzyme/_coenzyme | 0.37396979 |
99 | MP0003942_abnormal_urinary_system | 0.37151744 |
100 | MP0002133_abnormal_respiratory_system | 0.36041708 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Capillary hemangiomas (HP:0005306) | 6.00045052 |
2 | Nonimmune hydrops fetalis (HP:0001790) | 5.71845146 |
3 | Premature rupture of membranes (HP:0001788) | 5.69078279 |
4 | Protrusio acetabuli (HP:0003179) | 5.66132012 |
5 | Upper limb muscle weakness (HP:0003484) | 5.60397814 |
6 | Hypergonadotropic hypogonadism (HP:0000815) | 5.43581870 |
7 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 5.24926462 |
8 | Aortic aneurysm (HP:0004942) | 4.98304202 |
9 | Wormian bones (HP:0002645) | 4.62989599 |
10 | Aortic dissection (HP:0002647) | 3.93984266 |
11 | Accelerated skeletal maturation (HP:0005616) | 3.87798864 |
12 | Abnormal pupillary function (HP:0007686) | 3.78858726 |
13 | Vascular tortuosity (HP:0004948) | 3.76859595 |
14 | Muscle fibrillation (HP:0010546) | 3.70010994 |
15 | Fragile skin (HP:0001030) | 3.68728125 |
16 | Ankle contracture (HP:0006466) | 3.61340841 |
17 | Abnormal auditory evoked potentials (HP:0006958) | 3.60321506 |
18 | Tongue fasciculations (HP:0001308) | 3.58758317 |
19 | Soft skin (HP:0000977) | 3.52117259 |
20 | Blue sclerae (HP:0000592) | 3.36509271 |
21 | Back pain (HP:0003418) | 3.33671810 |
22 | Broad metatarsal (HP:0001783) | 3.22961665 |
23 | Follicular hyperkeratosis (HP:0007502) | 3.15627785 |
24 | Dilatation of the ascending aorta (HP:0005111) | 3.13327644 |
25 | Arterial tortuosity (HP:0005116) | 3.00773623 |
26 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.98690667 |
27 | Osteolytic defects of the hand bones (HP:0009699) | 2.98690667 |
28 | Bladder diverticulum (HP:0000015) | 2.93701966 |
29 | Anosmia (HP:0000458) | 2.93014756 |
30 | Disproportionate tall stature (HP:0001519) | 2.86436420 |
31 | Sparse lateral eyebrow (HP:0005338) | 2.83950356 |
32 | Overgrowth (HP:0001548) | 2.80990413 |
33 | Shallow orbits (HP:0000586) | 2.80394236 |
34 | Atrophic scars (HP:0001075) | 2.72516313 |
35 | Neonatal short-limb short stature (HP:0008921) | 2.71948321 |
36 | Female pseudohermaphroditism (HP:0010458) | 2.71118025 |
37 | Cardiovascular calcification (HP:0011915) | 2.69951581 |
38 | Genu valgum (HP:0002857) | 2.68083319 |
39 | Delayed gross motor development (HP:0002194) | 2.63807929 |
40 | Type 1 muscle fiber predominance (HP:0003803) | 2.62062507 |
41 | Elbow flexion contracture (HP:0002987) | 2.59603906 |
42 | Long palpebral fissure (HP:0000637) | 2.59037480 |
43 | Flat cornea (HP:0007720) | 2.55800642 |
44 | Morphological abnormality of the middle ear (HP:0008609) | 2.53838802 |
45 | Abnormality of dentin (HP:0010299) | 2.53362409 |
46 | Vertebral compression fractures (HP:0002953) | 2.53328758 |
47 | Cervical subluxation (HP:0003308) | 2.53306083 |
48 | Venous insufficiency (HP:0005293) | 2.50031548 |
49 | Abnormality of glycolipid metabolism (HP:0010969) | 2.48124472 |
50 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.48124472 |
51 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.48124472 |
52 | Spondylolisthesis (HP:0003302) | 2.41503653 |
53 | Abnormality of the ischium (HP:0003174) | 2.41417521 |
54 | Peritonitis (HP:0002586) | 2.39791156 |
55 | Long eyelashes (HP:0000527) | 2.39524926 |
56 | Spinal rigidity (HP:0003306) | 2.38378222 |
57 | Mitral valve prolapse (HP:0001634) | 2.36894069 |
58 | Cerebral aneurysm (HP:0004944) | 2.35310463 |
59 | Mitral regurgitation (HP:0001653) | 2.30505465 |
60 | Venous abnormality (HP:0002624) | 2.27805049 |
61 | Gynecomastia (HP:0000771) | 2.27378036 |
62 | Onion bulb formation (HP:0003383) | 2.24961645 |
63 | Bowel diverticulosis (HP:0005222) | 2.24706727 |
64 | Coronal craniosynostosis (HP:0004440) | 2.23720743 |
65 | Genu recurvatum (HP:0002816) | 2.23124261 |
66 | Hypoplasia of the iris (HP:0007676) | 2.22660547 |
67 | Aneurysm (HP:0002617) | 2.21167362 |
68 | Aortic valve stenosis (HP:0001650) | 2.20130794 |
69 | Lower limb asymmetry (HP:0100559) | 2.13966075 |
70 | Slender build (HP:0001533) | 2.12161697 |
71 | Protruding ear (HP:0000411) | 2.11560971 |
72 | Redundant skin (HP:0001582) | 2.11027831 |
73 | Knee flexion contracture (HP:0006380) | 2.09589692 |
74 | Increased connective tissue (HP:0009025) | 2.09312697 |
75 | Polycythemia (HP:0001901) | 2.08732228 |
76 | Mitral stenosis (HP:0001718) | 2.06684601 |
77 | Aplasia of the musculature (HP:0100854) | 2.02134881 |
78 | Tarsal synostosis (HP:0008368) | 1.94965113 |
79 | Distal lower limb muscle weakness (HP:0009053) | 1.93878719 |
80 | Aortic regurgitation (HP:0001659) | 1.93147470 |
81 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.91838569 |
82 | Joint laxity (HP:0001388) | 1.91070986 |
83 | Increased variability in muscle fiber diameter (HP:0003557) | 1.90433757 |
84 | Pseudobulbar signs (HP:0002200) | 1.90397945 |
85 | Areflexia of lower limbs (HP:0002522) | 1.88861051 |
86 | Abnormality of the acetabulum (HP:0003170) | 1.87142079 |
87 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.86418299 |
88 | Arachnodactyly (HP:0001166) | 1.84999245 |
89 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.84823716 |
90 | Difficulty walking (HP:0002355) | 1.83428679 |
91 | Wide anterior fontanel (HP:0000260) | 1.82983847 |
92 | Biconcave vertebral bodies (HP:0004586) | 1.81129058 |
93 | Vascular calcification (HP:0004934) | 1.81080106 |
94 | Ectopia lentis (HP:0001083) | 1.78890673 |
95 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.76020538 |
96 | Pectus carinatum (HP:0000768) | 1.75696355 |
97 | Basal cell carcinoma (HP:0002671) | 1.75261637 |
98 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.75023178 |
99 | Decreased motor nerve conduction velocity (HP:0003431) | 1.74968288 |
100 | Hip contracture (HP:0003273) | 1.74774424 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KDR | 7.85019463 |
2 | PDGFRA | 6.87448555 |
3 | AKT3 | 5.78694558 |
4 | MYLK | 3.53089179 |
5 | DAPK2 | 3.35138532 |
6 | NEK9 | 2.96168319 |
7 | PDGFRB | 2.64210632 |
8 | ICK | 2.27867038 |
9 | BLK | 1.72157061 |
10 | ERBB4 | 1.72142568 |
11 | MET | 1.48615690 |
12 | PAK2 | 1.47163948 |
13 | RIPK1 | 1.45597504 |
14 | TGFBR2 | 1.45349805 |
15 | STK38 | 1.44501839 |
16 | MST4 | 1.43881303 |
17 | DAPK3 | 1.42149637 |
18 | LATS1 | 1.34098962 |
19 | PRKD2 | 1.33489961 |
20 | DDR2 | 1.28140259 |
21 | TRPM7 | 1.25370374 |
22 | MST1R | 1.24910841 |
23 | TIE1 | 1.24820621 |
24 | PKN1 | 1.23223303 |
25 | EPHB2 | 1.19625455 |
26 | PTK2 | 1.16757765 |
27 | DAPK1 | 1.15125305 |
28 | RPS6KA2 | 1.12540230 |
29 | CDC42BPA | 1.08016068 |
30 | INSR | 0.94174772 |
31 | SRC | 0.92244206 |
32 | TTN | 0.90452868 |
33 | PDPK1 | 0.89886823 |
34 | MAP3K7 | 0.87751848 |
35 | FRK | 0.81052840 |
36 | TYK2 | 0.79542623 |
37 | MAP3K12 | 0.76212175 |
38 | TRIB3 | 0.75930767 |
39 | KIT | 0.75850106 |
40 | PTK2B | 0.74962006 |
41 | EPHA2 | 0.74820127 |
42 | INSRR | 0.74080057 |
43 | LATS2 | 0.74074178 |
44 | ADRBK1 | 0.74067397 |
45 | RPS6KL1 | 0.69914096 |
46 | RPS6KC1 | 0.69914096 |
47 | RPS6KA6 | 0.67593961 |
48 | MTOR | 0.63326961 |
49 | EGFR | 0.62693059 |
50 | NTRK1 | 0.62557769 |
51 | ROCK1 | 0.62081325 |
52 | PTK6 | 0.61356489 |
53 | ERN1 | 0.54863732 |
54 | MAP2K1 | 0.54373380 |
55 | PAK4 | 0.54274452 |
56 | PRKD1 | 0.50108633 |
57 | PRKCE | 0.49881689 |
58 | MELK | 0.49544182 |
59 | MAPK11 | 0.48618173 |
60 | GRK7 | 0.47097727 |
61 | BMX | 0.46210931 |
62 | ROCK2 | 0.46181918 |
63 | ABL2 | 0.45717786 |
64 | PIK3CG | 0.44728635 |
65 | PRKG2 | 0.44461521 |
66 | MARK2 | 0.44391703 |
67 | AKT2 | 0.43484779 |
68 | ILK | 0.39082517 |
69 | ADRBK2 | 0.37914141 |
70 | AURKB | 0.36528830 |
71 | GRK5 | 0.35279101 |
72 | CAMK2G | 0.34427251 |
73 | STK10 | 0.33630562 |
74 | PKN2 | 0.32649974 |
75 | STK3 | 0.32465020 |
76 | LIMK1 | 0.31745011 |
77 | MAPK7 | 0.31369602 |
78 | MAPK4 | 0.30434471 |
79 | JAK1 | 0.30100133 |
80 | MOS | 0.29556049 |
81 | FLT3 | 0.29498318 |
82 | MAP3K3 | 0.28416976 |
83 | BRSK2 | 0.27785678 |
84 | PDK1 | 0.27525293 |
85 | CDK8 | 0.27238413 |
86 | MAP3K6 | 0.27008654 |
87 | DYRK1B | 0.26908085 |
88 | PAK6 | 0.25872442 |
89 | PRKCZ | 0.25749395 |
90 | TBK1 | 0.25737907 |
91 | TESK1 | 0.24783067 |
92 | PLK2 | 0.24054812 |
93 | SIK1 | 0.23831241 |
94 | JAK2 | 0.22633208 |
95 | PRKCA | 0.21882543 |
96 | PIK3CA | 0.20392750 |
97 | ERBB3 | 0.18350178 |
98 | MAPK1 | 0.17142026 |
99 | PRKCH | 0.10937756 |
100 | SGK223 | 0.10266224 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 7.49972849 |
2 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 6.59111588 |
3 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 3.43159843 |
4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.62873785 |
5 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 2.32634752 |
6 | Focal adhesion_Homo sapiens_hsa04510 | 2.14689106 |
7 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.04860832 |
8 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.01138510 |
9 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.97771600 |
10 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.87735452 |
11 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.84385116 |
12 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.81258332 |
13 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.70351380 |
14 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.66700193 |
15 | Mineral absorption_Homo sapiens_hsa04978 | 1.53149073 |
16 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.30235349 |
17 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.25044276 |
18 | Axon guidance_Homo sapiens_hsa04360 | 1.22040181 |
19 | Other glycan degradation_Homo sapiens_hsa00511 | 1.19284828 |
20 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.15253754 |
21 | Ras signaling pathway_Homo sapiens_hsa04014 | 1.13527301 |
22 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.09789911 |
23 | Bladder cancer_Homo sapiens_hsa05219 | 1.07790517 |
24 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.07513675 |
25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.04368647 |
26 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.02830727 |
27 | Malaria_Homo sapiens_hsa05144 | 1.00756361 |
28 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.99431951 |
29 | Amoebiasis_Homo sapiens_hsa05146 | 0.97705996 |
30 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.95968692 |
31 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.95373331 |
32 | Salivary secretion_Homo sapiens_hsa04970 | 0.94933998 |
33 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.94674949 |
34 | Adherens junction_Homo sapiens_hsa04520 | 0.93042353 |
35 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.92233386 |
36 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.89366019 |
37 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.88153660 |
38 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.87049698 |
39 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.83259523 |
40 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.82685375 |
41 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.81426538 |
42 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.79688004 |
43 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.78045533 |
44 | Lysosome_Homo sapiens_hsa04142 | 0.77919334 |
45 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.77716480 |
46 | Tight junction_Homo sapiens_hsa04530 | 0.75453049 |
47 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.71721197 |
48 | Pathways in cancer_Homo sapiens_hsa05200 | 0.71683462 |
49 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.71046137 |
50 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.70621769 |
51 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67601316 |
52 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.66504300 |
53 | Endocytosis_Homo sapiens_hsa04144 | 0.65935448 |
54 | Melanoma_Homo sapiens_hsa05218 | 0.65292333 |
55 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.62968884 |
56 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.62401195 |
57 | Prostate cancer_Homo sapiens_hsa05215 | 0.61480095 |
58 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.60306249 |
59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.60234598 |
60 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.57424448 |
61 | Platelet activation_Homo sapiens_hsa04611 | 0.56449335 |
62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54961018 |
63 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.48466038 |
64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.48199058 |
65 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.46188866 |
66 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45746015 |
67 | Insulin resistance_Homo sapiens_hsa04931 | 0.41946639 |
68 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.41944819 |
69 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.40571716 |
70 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40102789 |
71 | Melanogenesis_Homo sapiens_hsa04916 | 0.39755484 |
72 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.38809114 |
73 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.37704538 |
74 | Gap junction_Homo sapiens_hsa04540 | 0.37445327 |
75 | Phagosome_Homo sapiens_hsa04145 | 0.36787931 |
76 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.34808566 |
77 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.34561209 |
78 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34450102 |
79 | Hepatitis B_Homo sapiens_hsa05161 | 0.32099650 |
80 | Glioma_Homo sapiens_hsa05214 | 0.32089073 |
81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.31692516 |
82 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31252656 |
83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.30881434 |
84 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.30538334 |
85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.30471195 |
86 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.30129780 |
87 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.29568436 |
88 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.28134671 |
89 | Hepatitis C_Homo sapiens_hsa05160 | 0.28006857 |
90 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.27545199 |
91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.25016405 |
92 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.23826984 |
93 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.23354121 |
94 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.23248202 |
95 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.22233155 |
96 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.21170198 |
97 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.19826194 |
98 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.19168381 |
99 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.18644551 |
100 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.18501722 |