

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | monoubiquitinated protein deubiquitination (GO:0035520) | 7.83436810 |
| 2 | outer ear morphogenesis (GO:0042473) | 7.73793797 |
| 3 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 6.67321383 |
| 4 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 6.67321383 |
| 5 | artery development (GO:0060840) | 6.25984438 |
| 6 | facial nerve structural organization (GO:0021612) | 5.47640368 |
| 7 | embryonic skeletal joint morphogenesis (GO:0060272) | 5.09714328 |
| 8 | endocardial cushion development (GO:0003197) | 4.89352089 |
| 9 | icosanoid secretion (GO:0032309) | 4.77042621 |
| 10 | arachidonic acid secretion (GO:0050482) | 4.77042621 |
| 11 | endosome to melanosome transport (GO:0035646) | 4.75509394 |
| 12 | endosome to pigment granule transport (GO:0043485) | 4.75509394 |
| 13 | kidney mesenchyme development (GO:0072074) | 4.72095836 |
| 14 | metanephric mesenchyme development (GO:0072075) | 4.44716288 |
| 15 | regulation of neurotransmitter uptake (GO:0051580) | 4.40400754 |
| 16 | cell migration involved in heart development (GO:0060973) | 4.29229162 |
| 17 | hyaluronan catabolic process (GO:0030214) | 4.28492231 |
| 18 | mesenchymal-epithelial cell signaling (GO:0060638) | 4.28356943 |
| 19 | musculoskeletal movement (GO:0050881) | 4.27309594 |
| 20 | multicellular organismal movement (GO:0050879) | 4.27309594 |
| 21 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 4.23835781 |
| 22 | prepulse inhibition (GO:0060134) | 4.22660162 |
| 23 | pericardium development (GO:0060039) | 4.17040454 |
| 24 | polyamine biosynthetic process (GO:0006596) | 4.12215489 |
| 25 | negative regulation of sodium ion transport (GO:0010766) | 4.11237696 |
| 26 | protein K48-linked deubiquitination (GO:0071108) | 4.05313806 |
| 27 | behavioral response to cocaine (GO:0048148) | 4.00500729 |
| 28 | regulation of proton transport (GO:0010155) | 3.89868500 |
| 29 | low-density lipoprotein particle clearance (GO:0034383) | 3.88920118 |
| 30 | G-protein coupled receptor internalization (GO:0002031) | 3.88736974 |
| 31 | synaptic transmission, dopaminergic (GO:0001963) | 3.87654032 |
| 32 | icosanoid transport (GO:0071715) | 3.84029566 |
| 33 | fatty acid derivative transport (GO:1901571) | 3.84029566 |
| 34 | base-excision repair, AP site formation (GO:0006285) | 3.80757974 |
| 35 | cranial nerve structural organization (GO:0021604) | 3.80684314 |
| 36 | negative regulation of membrane potential (GO:0045837) | 3.76976902 |
| 37 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.72269749 |
| 38 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.64199345 |
| 39 | platelet dense granule organization (GO:0060155) | 3.63731464 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.63544998 |
| 41 | cochlea morphogenesis (GO:0090103) | 3.54438287 |
| 42 | regulation of interleukin-8 secretion (GO:2000482) | 3.53787017 |
| 43 | eyelid development in camera-type eye (GO:0061029) | 3.52631165 |
| 44 | cellular biogenic amine biosynthetic process (GO:0042401) | 3.48985232 |
| 45 | response to redox state (GO:0051775) | 3.48703604 |
| 46 | positive regulation of gastrulation (GO:2000543) | 3.46438033 |
| 47 | estrogen biosynthetic process (GO:0006703) | 3.39173949 |
| 48 | response to histamine (GO:0034776) | 3.36316418 |
| 49 | protein import into peroxisome matrix (GO:0016558) | 3.36222730 |
| 50 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 3.22266968 |
| 51 | smooth muscle tissue development (GO:0048745) | 3.22167034 |
| 52 | amine biosynthetic process (GO:0009309) | 3.21883964 |
| 53 | embryonic forelimb morphogenesis (GO:0035115) | 3.15632077 |
| 54 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 3.12659773 |
| 55 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 3.11056919 |
| 56 | regulation of cardioblast proliferation (GO:0003264) | 3.11056919 |
| 57 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.09383445 |
| 58 | fibroblast migration (GO:0010761) | 3.07771379 |
| 59 | negative regulation of protein autophosphorylation (GO:0031953) | 3.05611831 |
| 60 | middle ear morphogenesis (GO:0042474) | 3.03702729 |
| 61 | ovulation cycle (GO:0042698) | 3.03217515 |
| 62 | endocrine hormone secretion (GO:0060986) | 3.01366839 |
| 63 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 3.00662222 |
| 64 | positive regulation of cellular amine metabolic process (GO:0033240) | 2.96095349 |
| 65 | fatty acid homeostasis (GO:0055089) | 2.94487673 |
| 66 | regulation of transforming growth factor beta1 production (GO:0032908) | 2.93968705 |
| 67 | mesonephros development (GO:0001823) | 2.91797597 |
| 68 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.91107113 |
| 69 | C21-steroid hormone biosynthetic process (GO:0006700) | 2.90807229 |
| 70 | reflex (GO:0060004) | 2.86406957 |
| 71 | head development (GO:0060322) | 2.85756012 |
| 72 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.82229550 |
| 73 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.79234731 |
| 74 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.76729648 |
| 75 | adipose tissue development (GO:0060612) | 2.74663247 |
| 76 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.73260229 |
| 77 | regulation of mitochondrial translation (GO:0070129) | 2.71138217 |
| 78 | natural killer cell mediated immunity (GO:0002228) | 2.69597137 |
| 79 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.69597137 |
| 80 | skin morphogenesis (GO:0043589) | 2.69446598 |
| 81 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.67862467 |
| 82 | regulation of endothelial cell differentiation (GO:0045601) | 2.65035056 |
| 83 | connective tissue development (GO:0061448) | 2.64904848 |
| 84 | forelimb morphogenesis (GO:0035136) | 2.63941205 |
| 85 | heparan sulfate proteoglycan metabolic process (GO:0030201) | 2.62338262 |
| 86 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 2.60322994 |
| 87 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.58604061 |
| 88 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 2.56328169 |
| 89 | cellular biogenic amine catabolic process (GO:0042402) | 2.55967925 |
| 90 | amine catabolic process (GO:0009310) | 2.55967925 |
| 91 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.53458416 |
| 92 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.53458416 |
| 93 | female pregnancy (GO:0007565) | 2.53147053 |
| 94 | positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745) | 2.52598383 |
| 95 | ventricular septum development (GO:0003281) | 2.52306579 |
| 96 | parental behavior (GO:0060746) | 2.50447604 |
| 97 | membrane raft organization (GO:0031579) | 2.49993010 |
| 98 | early endosome to late endosome transport (GO:0045022) | 2.48933219 |
| 99 | pattern specification involved in kidney development (GO:0061004) | 2.48717306 |
| 100 | regulation of fibroblast migration (GO:0010762) | 2.48372419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 7.02696216 |
| 2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 5.57712238 |
| 3 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.26057152 |
| 4 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.03803947 |
| 5 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.99284468 |
| 6 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.88845256 |
| 7 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.73765903 |
| 8 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.71955103 |
| 9 | TP53_18474530_ChIP-ChIP_U2OS_Human | 2.54877650 |
| 10 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.54164585 |
| 11 | CJUN_26792858_Chip-Seq_BT549_Human | 2.44290480 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.41617100 |
| 13 | BRD4_25478319_ChIP-Seq_HGPS_Human | 2.27657455 |
| 14 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.24756904 |
| 15 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.22042074 |
| 16 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.20664782 |
| 17 | TP53_16413492_ChIP-PET_HCT116_Human | 2.16853007 |
| 18 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.07761960 |
| 19 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.05940557 |
| 20 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.03870004 |
| 21 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.90872798 |
| 22 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.89240574 |
| 23 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.88503788 |
| 24 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.88503788 |
| 25 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.78996247 |
| 26 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.64371066 |
| 27 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.64371066 |
| 28 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.60084159 |
| 29 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.59689704 |
| 30 | RXR_22108803_ChIP-Seq_LS180_Human | 1.59099961 |
| 31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.58382724 |
| 32 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.49303283 |
| 33 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.47015781 |
| 34 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.46892129 |
| 35 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.43389746 |
| 36 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.39643017 |
| 37 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.39084347 |
| 38 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.37207013 |
| 39 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34629757 |
| 40 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.30725448 |
| 41 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.29744817 |
| 42 | GATA1_22025678_ChIP-Seq_K562_Human | 1.29313339 |
| 43 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.27296439 |
| 44 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.22194634 |
| 45 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.20927637 |
| 46 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.19528568 |
| 47 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.18645777 |
| 48 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18457503 |
| 49 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.17933626 |
| 50 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.17897769 |
| 51 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15209266 |
| 52 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 1.14413537 |
| 53 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.14022198 |
| 54 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.07862780 |
| 55 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.07501905 |
| 56 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.06663670 |
| 57 | JUN_21703547_ChIP-Seq_K562_Human | 1.05265924 |
| 58 | STAT3_23295773_ChIP-Seq_U87_Human | 1.04413509 |
| 59 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.03874906 |
| 60 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.03279336 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02268354 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02268354 |
| 63 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.02202269 |
| 64 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01940136 |
| 65 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01187141 |
| 66 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.00190127 |
| 67 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.98014068 |
| 68 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.96977723 |
| 69 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.95920686 |
| 70 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95808305 |
| 71 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.95603940 |
| 72 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.93693935 |
| 73 | P300_19829295_ChIP-Seq_ESCs_Human | 0.92618301 |
| 74 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.91735145 |
| 75 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.89414542 |
| 76 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88451959 |
| 77 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.88213940 |
| 78 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.86827089 |
| 79 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.86805244 |
| 80 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.86069802 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.85085116 |
| 82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.85085116 |
| 83 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.84663109 |
| 84 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.84182358 |
| 85 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.83160092 |
| 86 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.82556443 |
| 87 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.82455398 |
| 88 | TCF4_23295773_ChIP-Seq_U87_Human | 0.82426637 |
| 89 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.82278687 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.81839909 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.81839909 |
| 92 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.81475267 |
| 93 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.80818411 |
| 94 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.80729041 |
| 95 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.79909386 |
| 96 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.79792079 |
| 97 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.78910273 |
| 98 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.78812971 |
| 99 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77945596 |
| 100 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.77474383 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005451_abnormal_body_composition | 5.99686168 |
| 2 | MP0003646_muscle_fatigue | 5.49322704 |
| 3 | MP0005503_abnormal_tendon_morphology | 4.25692639 |
| 4 | MP0003950_abnormal_plasma_membrane | 3.88387388 |
| 5 | MP0004272_abnormal_basement_membrane | 3.18104566 |
| 6 | MP0008438_abnormal_cutaneous_collagen | 3.03143227 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.88543435 |
| 8 | MP0001542_abnormal_bone_strength | 2.57127117 |
| 9 | MP0003941_abnormal_skin_development | 2.56781188 |
| 10 | MP0001905_abnormal_dopamine_level | 2.50593425 |
| 11 | MP0002736_abnormal_nociception_after | 2.37171374 |
| 12 | MP0009046_muscle_twitch | 2.33228724 |
| 13 | MP0003195_calcinosis | 2.23009380 |
| 14 | MP0010386_abnormal_urinary_bladder | 2.22767809 |
| 15 | MP0000538_abnormal_urinary_bladder | 2.03335938 |
| 16 | MP0002295_abnormal_pulmonary_circulatio | 1.92809795 |
| 17 | MP0002735_abnormal_chemical_nociception | 1.88530500 |
| 18 | MP0002108_abnormal_muscle_morphology | 1.86691065 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.83743392 |
| 20 | MP0003705_abnormal_hypodermis_morpholog | 1.82810055 |
| 21 | MP0005023_abnormal_wound_healing | 1.81037972 |
| 22 | MP0000678_abnormal_parathyroid_gland | 1.79172969 |
| 23 | MP0008775_abnormal_heart_ventricle | 1.76842365 |
| 24 | MP0003806_abnormal_nucleotide_metabolis | 1.62796567 |
| 25 | MP0010368_abnormal_lymphatic_system | 1.61446150 |
| 26 | MP0005275_abnormal_skin_tensile | 1.58015208 |
| 27 | MP0003252_abnormal_bile_duct | 1.55889438 |
| 28 | MP0003122_maternal_imprinting | 1.55565706 |
| 29 | MP0001958_emphysema | 1.52030590 |
| 30 | MP0005257_abnormal_intraocular_pressure | 1.50890585 |
| 31 | MP0001756_abnormal_urination | 1.49223266 |
| 32 | MP0006054_spinal_hemorrhage | 1.48434406 |
| 33 | MP0005508_abnormal_skeleton_morphology | 1.46432900 |
| 34 | MP0009780_abnormal_chondrocyte_physiolo | 1.43706250 |
| 35 | MP0001299_abnormal_eye_distance/ | 1.42884153 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.41842446 |
| 37 | MP0001440_abnormal_grooming_behavior | 1.41701446 |
| 38 | MP0004133_heterotaxia | 1.39103133 |
| 39 | MP0000230_abnormal_systemic_arterial | 1.36820834 |
| 40 | MP0002928_abnormal_bile_duct | 1.35905869 |
| 41 | MP0004130_abnormal_muscle_cell | 1.35477973 |
| 42 | MP0001486_abnormal_startle_reflex | 1.34365746 |
| 43 | MP0003191_abnormal_cellular_cholesterol | 1.30100190 |
| 44 | MP0001529_abnormal_vocalization | 1.29885995 |
| 45 | MP0005408_hypopigmentation | 1.29512533 |
| 46 | MP0003942_abnormal_urinary_system | 1.28083361 |
| 47 | MP0008872_abnormal_physiological_respon | 1.27726301 |
| 48 | MP0009250_abnormal_appendicular_skeleto | 1.24039099 |
| 49 | MP0000537_abnormal_urethra_morphology | 1.21449305 |
| 50 | MP0000049_abnormal_middle_ear | 1.21091364 |
| 51 | MP0002877_abnormal_melanocyte_morpholog | 1.18054725 |
| 52 | MP0001853_heart_inflammation | 1.17713564 |
| 53 | MP0002876_abnormal_thyroid_physiology | 1.16706235 |
| 54 | MP0000681_abnormal_thyroid_gland | 1.15550955 |
| 55 | MP0002177_abnormal_outer_ear | 1.13179040 |
| 56 | MP0009384_cardiac_valve_regurgitation | 1.12468482 |
| 57 | MP0010352_gastrointestinal_tract_polyps | 1.08718574 |
| 58 | MP0010030_abnormal_orbit_morphology | 1.05798136 |
| 59 | MP0001270_distended_abdomen | 1.04856308 |
| 60 | MP0005595_abnormal_vascular_smooth | 1.03476921 |
| 61 | MP0003279_aneurysm | 1.00198594 |
| 62 | MP0003755_abnormal_palate_morphology | 0.98164994 |
| 63 | MP0005084_abnormal_gallbladder_morpholo | 0.97645340 |
| 64 | MP0002163_abnormal_gland_morphology | 0.95863618 |
| 65 | MP0001970_abnormal_pain_threshold | 0.95769320 |
| 66 | MP0005332_abnormal_amino_acid | 0.95186535 |
| 67 | MP0005187_abnormal_penis_morphology | 0.94987472 |
| 68 | MP0004924_abnormal_behavior | 0.91977493 |
| 69 | MP0005386_behavior/neurological_phenoty | 0.91977493 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.90557502 |
| 71 | MP0003186_abnormal_redox_activity | 0.89825227 |
| 72 | MP0002733_abnormal_thermal_nociception | 0.89355584 |
| 73 | MP0000003_abnormal_adipose_tissue | 0.89240151 |
| 74 | MP0009697_abnormal_copulation | 0.88795257 |
| 75 | MP0000343_altered_response_to | 0.86644292 |
| 76 | MP0000647_abnormal_sebaceous_gland | 0.86105001 |
| 77 | MP0000372_irregular_coat_pigmentation | 0.85292602 |
| 78 | MP0001348_abnormal_lacrimal_gland | 0.81904865 |
| 79 | MP0005220_abnormal_exocrine_pancreas | 0.76569259 |
| 80 | MP0001984_abnormal_olfaction | 0.75420101 |
| 81 | MP0005367_renal/urinary_system_phenotyp | 0.74247624 |
| 82 | MP0000516_abnormal_urinary_system | 0.74247624 |
| 83 | MP0000639_abnormal_adrenal_gland | 0.71573007 |
| 84 | MP0002796_impaired_skin_barrier | 0.71106768 |
| 85 | MP0005360_urolithiasis | 0.70945880 |
| 86 | MP0005174_abnormal_tail_pigmentation | 0.70915715 |
| 87 | MP0003937_abnormal_limbs/digits/tail_de | 0.70526722 |
| 88 | MP0005164_abnormal_response_to | 0.70133308 |
| 89 | MP0005646_abnormal_pituitary_gland | 0.70059517 |
| 90 | MP0005390_skeleton_phenotype | 0.69097150 |
| 91 | MP0005620_abnormal_muscle_contractility | 0.66793884 |
| 92 | MP0003890_abnormal_embryonic-extraembry | 0.66697760 |
| 93 | MP0004742_abnormal_vestibular_system | 0.65509846 |
| 94 | MP0000427_abnormal_hair_cycle | 0.64122360 |
| 95 | MP0010771_integument_phenotype | 0.58905008 |
| 96 | MP0002168_other_aberrant_phenotype | 0.57924945 |
| 97 | MP0000534_abnormal_ureter_morphology | 0.57367590 |
| 98 | MP0002136_abnormal_kidney_physiology | 0.57011603 |
| 99 | MP0009840_abnormal_foam_cell | 0.55859125 |
| 100 | MP0003315_abnormal_perineum_morphology | 0.55312527 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cutaneous melanoma (HP:0012056) | 8.82394077 |
| 2 | Short nail (HP:0001799) | 7.16534604 |
| 3 | Spinal cord compression (HP:0002176) | 6.22395035 |
| 4 | Ovoid vertebral bodies (HP:0003300) | 5.81936399 |
| 5 | Broad distal phalanx of finger (HP:0009836) | 5.46898495 |
| 6 | 11 pairs of ribs (HP:0000878) | 5.09057602 |
| 7 | Flared iliac wings (HP:0002869) | 4.99455975 |
| 8 | Radial bowing (HP:0002986) | 4.55387444 |
| 9 | Meningioma (HP:0002858) | 4.29885452 |
| 10 | Cupped ribs (HP:0000887) | 4.28026923 |
| 11 | Delayed gross motor development (HP:0002194) | 4.19634962 |
| 12 | Irregular vertebral endplates (HP:0003301) | 4.02189678 |
| 13 | Fragile skin (HP:0001030) | 3.78878622 |
| 14 | Abnormality of carpal bone ossification (HP:0006257) | 3.74035081 |
| 15 | Soft skin (HP:0000977) | 3.68063158 |
| 16 | Exostoses (HP:0100777) | 3.60721423 |
| 17 | Hypoplastic ischia (HP:0003175) | 3.52200391 |
| 18 | Hydroxyprolinuria (HP:0003080) | 3.31815197 |
| 19 | Abnormality of proline metabolism (HP:0010907) | 3.31815197 |
| 20 | Abnormality of the ischium (HP:0003174) | 3.17986435 |
| 21 | Short femoral neck (HP:0100864) | 3.12840502 |
| 22 | Bowed forearm bones (HP:0003956) | 3.06136517 |
| 23 | Bowing of the arm (HP:0006488) | 3.06136517 |
| 24 | Broad metatarsal (HP:0001783) | 2.97715227 |
| 25 | Aortic aneurysm (HP:0004942) | 2.91429739 |
| 26 | Abnormality of the vertebral endplates (HP:0005106) | 2.91412478 |
| 27 | Albinism (HP:0001022) | 2.83149421 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.81484697 |
| 29 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 2.80635513 |
| 30 | Methylmalonic aciduria (HP:0012120) | 2.79160867 |
| 31 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.79078174 |
| 32 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.79078174 |
| 33 | Abnormality of glycolipid metabolism (HP:0010969) | 2.79078174 |
| 34 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.67258421 |
| 35 | Methylmalonic acidemia (HP:0002912) | 2.65408720 |
| 36 | Melanoma (HP:0002861) | 2.61337437 |
| 37 | Abnormal hand bone ossification (HP:0010660) | 2.59958749 |
| 38 | Bicuspid aortic valve (HP:0001647) | 2.57531041 |
| 39 | Abnormal ossification of hand bones (HP:0005921) | 2.54855680 |
| 40 | Coxa valga (HP:0002673) | 2.54681094 |
| 41 | Cardiovascular calcification (HP:0011915) | 2.53411946 |
| 42 | Missing ribs (HP:0000921) | 2.49733168 |
| 43 | Vascular calcification (HP:0004934) | 2.49261007 |
| 44 | Mitral regurgitation (HP:0001653) | 2.48399443 |
| 45 | Coronal craniosynostosis (HP:0004440) | 2.45182124 |
| 46 | Mesomelia (HP:0003027) | 2.44768161 |
| 47 | Premature rupture of membranes (HP:0001788) | 2.42807418 |
| 48 | Deviation of the hallux (HP:0010051) | 2.42247641 |
| 49 | Dislocated radial head (HP:0003083) | 2.41859204 |
| 50 | Hyperglycinemia (HP:0002154) | 2.40999706 |
| 51 | Mesangial abnormality (HP:0001966) | 2.40766312 |
| 52 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 2.40675216 |
| 53 | Vascular tortuosity (HP:0004948) | 2.35088598 |
| 54 | Hallux valgus (HP:0001822) | 2.32211969 |
| 55 | Metatarsus adductus (HP:0001840) | 2.29812000 |
| 56 | Abnormality of the radial head (HP:0003995) | 2.26166733 |
| 57 | Hypoplasia of the uterus (HP:0000013) | 2.25375434 |
| 58 | Aplasia/hypoplasia of the femur (HP:0005613) | 2.18209579 |
| 59 | Furrowed tongue (HP:0000221) | 2.17936603 |
| 60 | Slender long bone (HP:0003100) | 2.10070855 |
| 61 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.09772624 |
| 62 | Abnormality of the wing of the ilium (HP:0011867) | 2.07294232 |
| 63 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.06183204 |
| 64 | Aplasia of the musculature (HP:0100854) | 2.04030012 |
| 65 | Microglossia (HP:0000171) | 2.03879783 |
| 66 | Flat face (HP:0012368) | 2.01495165 |
| 67 | Congenital primary aphakia (HP:0007707) | 2.00652987 |
| 68 | Lymphangioma (HP:0100764) | 1.98421688 |
| 69 | Gait imbalance (HP:0002141) | 1.96334565 |
| 70 | Absent phalangeal crease (HP:0006109) | 1.96286778 |
| 71 | Benign neoplasm of the central nervous system (HP:0100835) | 1.93815517 |
| 72 | Large for gestational age (HP:0001520) | 1.92562561 |
| 73 | Neoplasm of the lung (HP:0100526) | 1.90540072 |
| 74 | Pathologic fracture (HP:0002756) | 1.87397755 |
| 75 | Partial duplication of the phalanx of hand (HP:0009999) | 1.87206169 |
| 76 | Aortic dissection (HP:0002647) | 1.86691475 |
| 77 | Craniofacial hyperostosis (HP:0004493) | 1.85701406 |
| 78 | Cervical subluxation (HP:0003308) | 1.83993948 |
| 79 | Enlarged penis (HP:0000040) | 1.79210784 |
| 80 | Abnormal vertebral ossification (HP:0100569) | 1.78667991 |
| 81 | Glucose intolerance (HP:0000833) | 1.78360187 |
| 82 | True hermaphroditism (HP:0010459) | 1.77588415 |
| 83 | Buphthalmos (HP:0000557) | 1.76971936 |
| 84 | Abnormality of dentin (HP:0010299) | 1.76405893 |
| 85 | Asymmetric septal hypertrophy (HP:0001670) | 1.76356976 |
| 86 | Protrusio acetabuli (HP:0003179) | 1.75865572 |
| 87 | Sparse scalp hair (HP:0002209) | 1.75562305 |
| 88 | Blue sclerae (HP:0000592) | 1.75128796 |
| 89 | Dysostosis multiplex (HP:0000943) | 1.74898132 |
| 90 | Medial flaring of the eyebrow (HP:0010747) | 1.74414255 |
| 91 | Ectopia lentis (HP:0001083) | 1.74055283 |
| 92 | Hypophosphatemic rickets (HP:0004912) | 1.72114461 |
| 93 | Severe short stature (HP:0003510) | 1.70789279 |
| 94 | Conical tooth (HP:0000698) | 1.70165197 |
| 95 | Vertebral compression fractures (HP:0002953) | 1.69327764 |
| 96 | Spondylolisthesis (HP:0003302) | 1.67848776 |
| 97 | Supernumerary nipples (HP:0002558) | 1.66505521 |
| 98 | Nephrogenic diabetes insipidus (HP:0009806) | 1.65975839 |
| 99 | Hamartoma of the eye (HP:0010568) | 1.65826122 |
| 100 | Bell-shaped thorax (HP:0001591) | 1.65128676 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.80260481 |
| 2 | MYLK | 4.91850986 |
| 3 | ACVR1B | 3.72267986 |
| 4 | TRPM7 | 3.01893518 |
| 5 | MAP3K12 | 2.86946358 |
| 6 | GRK7 | 2.72981051 |
| 7 | ADRBK2 | 2.43037043 |
| 8 | MAP3K2 | 2.42002580 |
| 9 | NEK9 | 2.38772342 |
| 10 | LIMK1 | 2.32329597 |
| 11 | MAP3K13 | 2.27768142 |
| 12 | EPHA2 | 2.27649656 |
| 13 | GRK1 | 2.18430081 |
| 14 | MAPKAPK3 | 2.15253711 |
| 15 | PAK2 | 2.00622128 |
| 16 | EPHB2 | 1.85638818 |
| 17 | NTRK3 | 1.83384216 |
| 18 | BMPR1B | 1.79760331 |
| 19 | DDR2 | 1.76771861 |
| 20 | KSR2 | 1.74112134 |
| 21 | PAK6 | 1.73762568 |
| 22 | FGFR2 | 1.64889610 |
| 23 | WNK1 | 1.62923792 |
| 24 | MET | 1.61395523 |
| 25 | TGFBR1 | 1.55814177 |
| 26 | TLK1 | 1.49642971 |
| 27 | NEK1 | 1.44266089 |
| 28 | ADRBK1 | 1.38060724 |
| 29 | RAF1 | 1.36302871 |
| 30 | PTK2B | 1.35305910 |
| 31 | MAP2K1 | 1.26649116 |
| 32 | PLK2 | 1.24010621 |
| 33 | PTK2 | 1.22410234 |
| 34 | AKT3 | 1.18984891 |
| 35 | MST1R | 1.15621910 |
| 36 | PAK3 | 1.15130420 |
| 37 | KSR1 | 1.14220882 |
| 38 | EEF2K | 1.11873186 |
| 39 | NUAK1 | 1.10507322 |
| 40 | ROCK1 | 1.09841861 |
| 41 | FLT3 | 1.08849580 |
| 42 | PDGFRA | 1.04098667 |
| 43 | ERBB4 | 1.01608300 |
| 44 | ABL2 | 0.98883940 |
| 45 | NTRK1 | 0.93262887 |
| 46 | ILK | 0.88617581 |
| 47 | TIE1 | 0.85984761 |
| 48 | JAK1 | 0.85129302 |
| 49 | BCKDK | 0.84824460 |
| 50 | BRSK2 | 0.81597927 |
| 51 | MAPKAPK5 | 0.80512200 |
| 52 | ERBB3 | 0.79489378 |
| 53 | NEK2 | 0.75225592 |
| 54 | ZAK | 0.74728491 |
| 55 | PRKD2 | 0.74483525 |
| 56 | MAP3K3 | 0.73623851 |
| 57 | CSNK1A1L | 0.72319698 |
| 58 | CAMK2G | 0.71558111 |
| 59 | PRKCE | 0.69958678 |
| 60 | MAP3K7 | 0.68605970 |
| 61 | STK38L | 0.68189743 |
| 62 | LATS2 | 0.66549007 |
| 63 | CSNK1G3 | 0.63789373 |
| 64 | PKN1 | 0.60591999 |
| 65 | PLK3 | 0.57644779 |
| 66 | PRKAA2 | 0.56301790 |
| 67 | STK16 | 0.56014776 |
| 68 | PIM2 | 0.55286337 |
| 69 | PDGFRB | 0.54754261 |
| 70 | KDR | 0.51095689 |
| 71 | MAPK13 | 0.48380689 |
| 72 | PIK3CA | 0.47644967 |
| 73 | RIPK1 | 0.46812098 |
| 74 | DAPK3 | 0.45937275 |
| 75 | CSNK1G1 | 0.44710811 |
| 76 | BRSK1 | 0.42740349 |
| 77 | MELK | 0.39913139 |
| 78 | CAMK2D | 0.39808117 |
| 79 | PIK3CG | 0.39287979 |
| 80 | FER | 0.38406167 |
| 81 | CSNK1G2 | 0.36906512 |
| 82 | TGFBR2 | 0.36704285 |
| 83 | CDK8 | 0.36553879 |
| 84 | PINK1 | 0.36322702 |
| 85 | STK38 | 0.35038453 |
| 86 | IKBKB | 0.34509211 |
| 87 | RET | 0.31087714 |
| 88 | PRKD1 | 0.31049467 |
| 89 | CAMK2B | 0.30834091 |
| 90 | PBK | 0.30062272 |
| 91 | PRKCI | 0.28269149 |
| 92 | PRKCQ | 0.27862571 |
| 93 | KIT | 0.27047145 |
| 94 | STK24 | 0.26547068 |
| 95 | MARK1 | 0.26082596 |
| 96 | FGFR1 | 0.25896784 |
| 97 | GRK5 | 0.23068880 |
| 98 | CAMK2A | 0.21226818 |
| 99 | PAK1 | 0.20141224 |
| 100 | INSR | 0.19643802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 5.45452762 |
| 2 | Selenocompound metabolism_Homo sapiens_hsa00450 | 5.01792958 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 4.36344869 |
| 4 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.23625655 |
| 5 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.69061152 |
| 6 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.38306727 |
| 7 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.20613865 |
| 8 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.16956362 |
| 9 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.83911280 |
| 10 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.81255010 |
| 11 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.78318278 |
| 12 | Phototransduction_Homo sapiens_hsa04744 | 1.78216752 |
| 13 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.64634010 |
| 14 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.57219477 |
| 15 | Other glycan degradation_Homo sapiens_hsa00511 | 1.55730601 |
| 16 | Peroxisome_Homo sapiens_hsa04146 | 1.54865868 |
| 17 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.49263327 |
| 18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.45949781 |
| 19 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.44283175 |
| 20 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.30191974 |
| 21 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.29039144 |
| 22 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.28379902 |
| 23 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.27238021 |
| 24 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.24733676 |
| 25 | Lysosome_Homo sapiens_hsa04142 | 1.23011053 |
| 26 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.21937555 |
| 27 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.18975470 |
| 28 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.16622007 |
| 29 | Melanoma_Homo sapiens_hsa05218 | 1.11052641 |
| 30 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.09975618 |
| 31 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.07890686 |
| 32 | Mineral absorption_Homo sapiens_hsa04978 | 1.07003365 |
| 33 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.06667443 |
| 34 | Circadian rhythm_Homo sapiens_hsa04710 | 1.06284315 |
| 35 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.98341765 |
| 36 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.96623084 |
| 37 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.90370572 |
| 38 | ABC transporters_Homo sapiens_hsa02010 | 0.89769266 |
| 39 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.89211845 |
| 40 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86352402 |
| 41 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.85501416 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.78991613 |
| 43 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.78408115 |
| 44 | Cocaine addiction_Homo sapiens_hsa05030 | 0.73547940 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.73029657 |
| 46 | Focal adhesion_Homo sapiens_hsa04510 | 0.71689783 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70760953 |
| 48 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.69083352 |
| 49 | Galactose metabolism_Homo sapiens_hsa00052 | 0.68396603 |
| 50 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.63626616 |
| 51 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.60789830 |
| 52 | Proteasome_Homo sapiens_hsa03050 | 0.59647342 |
| 53 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.59445974 |
| 54 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.58673101 |
| 55 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.57280677 |
| 56 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.57067889 |
| 57 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.56703490 |
| 58 | Sulfur relay system_Homo sapiens_hsa04122 | 0.55109026 |
| 59 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53503472 |
| 60 | Endocytosis_Homo sapiens_hsa04144 | 0.51606881 |
| 61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50979065 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50369590 |
| 63 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.50042766 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49078205 |
| 65 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.48865069 |
| 66 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.48793739 |
| 67 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.46951490 |
| 68 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.46461472 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46423628 |
| 70 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.46260676 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45481565 |
| 72 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.44002953 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42595506 |
| 74 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.42449789 |
| 75 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.38676438 |
| 76 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.36005525 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35966014 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.35739755 |
| 79 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34560014 |
| 80 | Base excision repair_Homo sapiens_hsa03410 | 0.31302273 |
| 81 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.30204304 |
| 82 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.29876231 |
| 83 | Phagosome_Homo sapiens_hsa04145 | 0.29683245 |
| 84 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.29496795 |
| 85 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.29284850 |
| 86 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.29106294 |
| 87 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.28404958 |
| 88 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.27861376 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.27218693 |
| 90 | Tight junction_Homo sapiens_hsa04530 | 0.26576700 |
| 91 | Bladder cancer_Homo sapiens_hsa05219 | 0.23935587 |
| 92 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.23479484 |
| 93 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23378342 |
| 94 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.22798692 |
| 95 | Morphine addiction_Homo sapiens_hsa05032 | 0.21656134 |
| 96 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.20773477 |
| 97 | Malaria_Homo sapiens_hsa05144 | 0.20583368 |
| 98 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.19213766 |
| 99 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.18728972 |
| 100 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.18175667 |

