PSIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chromatin remodeling at centromere (GO:0031055)4.80672658
2CENP-A containing nucleosome assembly (GO:0034080)4.60236077
3mitotic sister chromatid cohesion (GO:0007064)4.24319605
4regulation of gene silencing by RNA (GO:0060966)4.15585586
5regulation of posttranscriptional gene silencing (GO:0060147)4.15585586
6regulation of gene silencing by miRNA (GO:0060964)4.15585586
7DNA strand elongation involved in DNA replication (GO:0006271)3.97766830
8DNA replication checkpoint (GO:0000076)3.78648663
9DNA strand elongation (GO:0022616)3.78608420
10pre-miRNA processing (GO:0031054)3.75084963
11negative regulation of DNA-dependent DNA replication (GO:2000104)3.66846776
12DNA topological change (GO:0006265)3.66324518
13DNA ligation (GO:0006266)3.58244511
14telomere maintenance via semi-conservative replication (GO:0032201)3.56517892
15nuclear pore complex assembly (GO:0051292)3.52940576
16regulation of helicase activity (GO:0051095)3.52357650
17* establishment of integrated proviral latency (GO:0075713)3.45090534
18negative regulation of sister chromatid segregation (GO:0033046)3.39863958
19negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.39863958
20negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.39863958
21negative regulation of mitotic sister chromatid segregation (GO:0033048)3.39863958
22negative regulation of mitotic sister chromatid separation (GO:2000816)3.39863958
23negative regulation of chromosome segregation (GO:0051985)3.38790987
24regulation of centriole replication (GO:0046599)3.31445877
25layer formation in cerebral cortex (GO:0021819)3.30438436
26somatic hypermutation of immunoglobulin genes (GO:0016446)3.27837268
27somatic diversification of immune receptors via somatic mutation (GO:0002566)3.27837268
28nuclear pore organization (GO:0006999)3.27754988
29negative regulation of translation, ncRNA-mediated (GO:0040033)3.27209934
30regulation of translation, ncRNA-mediated (GO:0045974)3.27209934
31negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.27209934
32regulation of mitotic spindle checkpoint (GO:1903504)3.27149421
33regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.27149421
34regulation of sister chromatid segregation (GO:0033045)3.24538217
35regulation of mitotic sister chromatid separation (GO:0010965)3.24538217
36regulation of mitotic sister chromatid segregation (GO:0033047)3.24538217
37DNA unwinding involved in DNA replication (GO:0006268)3.23193993
38regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.22845808
39regulation of mitotic metaphase/anaphase transition (GO:0030071)3.22845808
40metaphase plate congression (GO:0051310)3.22193673
41mitotic recombination (GO:0006312)3.21991089
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.19282001
43negative regulation of mRNA processing (GO:0050686)3.18938695
44spindle checkpoint (GO:0031577)3.16967600
45L-serine metabolic process (GO:0006563)3.14934569
46telomere maintenance via recombination (GO:0000722)3.12554114
47DNA double-strand break processing (GO:0000729)3.10968471
48mitotic spindle checkpoint (GO:0071174)3.10477376
49negative regulation of RNA splicing (GO:0033119)3.10265156
50DNA replication initiation (GO:0006270)3.10204600
51negative regulation of DNA recombination (GO:0045910)3.07107129
52negative regulation of histone methylation (GO:0031061)3.06818073
53non-recombinational repair (GO:0000726)3.06090299
54double-strand break repair via nonhomologous end joining (GO:0006303)3.06090299
55regulation of RNA export from nucleus (GO:0046831)3.05174569
56sister chromatid segregation (GO:0000819)3.02987762
57mitotic spindle assembly checkpoint (GO:0007094)3.02123622
58mitotic chromosome condensation (GO:0007076)3.01631266
59neuron cell-cell adhesion (GO:0007158)3.01006893
60regulation of short-term neuronal synaptic plasticity (GO:0048172)2.99421732
61regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.97008661
62spindle assembly checkpoint (GO:0071173)2.96091627
63negative regulation of mRNA metabolic process (GO:1903312)2.95714965
64mitotic G2/M transition checkpoint (GO:0044818)2.95637862
65regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.94147334
66regulation of nuclear cell cycle DNA replication (GO:0033262)2.92421159
67paraxial mesoderm development (GO:0048339)2.91769635
68nucleotide-excision repair, DNA gap filling (GO:0006297)2.90318681
69positive regulation of dendritic spine morphogenesis (GO:0061003)2.88886989
70protein complex localization (GO:0031503)2.87170264
71IMP biosynthetic process (GO:0006188)2.85583663
72dendritic spine morphogenesis (GO:0060997)2.85396591
73telomere maintenance via telomerase (GO:0007004)2.85276499
74cilium or flagellum-dependent cell motility (GO:0001539)2.83130259
75regulation of sister chromatid cohesion (GO:0007063)2.82585223
76telomere maintenance via telomere lengthening (GO:0010833)2.80994481
77establishment of chromosome localization (GO:0051303)2.79979893
78mitotic sister chromatid segregation (GO:0000070)2.79762045
79kinetochore organization (GO:0051383)2.79253708
80peptidyl-arginine methylation (GO:0018216)2.78621430
81peptidyl-arginine N-methylation (GO:0035246)2.78621430
82positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.77755659
83protein localization to chromosome (GO:0034502)2.75901967
84axonal fasciculation (GO:0007413)2.75622365
85locomotory exploration behavior (GO:0035641)2.73863647
86protein localization to synapse (GO:0035418)2.73823726
87purine nucleobase biosynthetic process (GO:0009113)2.73725549
88sister chromatid cohesion (GO:0007062)2.72831398
89termination of RNA polymerase II transcription (GO:0006369)2.71926653
90regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.71757990
91negative regulation of mitosis (GO:0045839)2.70889029
92regulation of histone H3-K9 methylation (GO:0051570)2.69015514
93presynaptic membrane organization (GO:0097090)2.68371123
94neuron recognition (GO:0008038)2.68095646
95V(D)J recombination (GO:0033151)2.67705764
96regulation of gene silencing (GO:0060968)2.66717118
97piRNA metabolic process (GO:0034587)2.63521291
98microtubule depolymerization (GO:0007019)2.62198226
99synaptic vesicle exocytosis (GO:0016079)2.60752847
100* mRNA splice site selection (GO:0006376)2.58866401
101regulation of DNA endoreduplication (GO:0032875)2.58296639
102peptidyl-arginine omega-N-methylation (GO:0035247)2.57172650
103male meiosis (GO:0007140)2.54974079
104DNA replication-dependent nucleosome assembly (GO:0006335)2.54536503
105DNA replication-dependent nucleosome organization (GO:0034723)2.54536503
106regulation of centrosome cycle (GO:0046605)2.54193752
107vocalization behavior (GO:0071625)2.53304339
108monoubiquitinated protein deubiquitination (GO:0035520)2.53298330
109regulation of nucleobase-containing compound transport (GO:0032239)2.52750384
110regulation of meiosis I (GO:0060631)2.51107255
111synaptic vesicle maturation (GO:0016188)2.51068121
112protein localization to kinetochore (GO:0034501)2.50385714
113glucocorticoid receptor signaling pathway (GO:0042921)2.49055072
114regulation of glutamate receptor signaling pathway (GO:1900449)2.47906286
115negative regulation of DNA repair (GO:0045738)2.47143278
116ionotropic glutamate receptor signaling pathway (GO:0035235)2.46373705
117negative regulation of organelle assembly (GO:1902116)2.44524814
118gene silencing by RNA (GO:0031047)2.42909727
119cell migration in hindbrain (GO:0021535)2.42297263
120protein localization to chromosome, centromeric region (GO:0071459)2.41989557
121regulation of centrosome duplication (GO:0010824)2.41920119
122positive regulation of mitotic sister chromatid separation (GO:1901970)2.41860618
123positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.41860618
124positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.41860618
125establishment of nucleus localization (GO:0040023)2.41315992
126negative regulation of histone modification (GO:0031057)2.40302295
127histone exchange (GO:0043486)2.39723383
128peptidyl-lysine dimethylation (GO:0018027)2.36524150
129regulation of synaptic vesicle exocytosis (GO:2000300)2.35814521
130regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.34007855
131exploration behavior (GO:0035640)2.33942757
132chromatin assembly (GO:0031497)2.32693270
133glutamate receptor signaling pathway (GO:0007215)2.32173586
134central nervous system projection neuron axonogenesis (GO:0021952)2.31964984
135regulation of chromosome segregation (GO:0051983)2.30960562
136heterochromatin organization (GO:0070828)2.30005923
137ATP-dependent chromatin remodeling (GO:0043044)2.29861437
138pore complex assembly (GO:0046931)2.29837522
139attachment of spindle microtubules to kinetochore (GO:0008608)2.29649414
140positive regulation of synapse maturation (GO:0090129)2.29267250
141regulation of dendritic spine morphogenesis (GO:0061001)2.29111222
142regulation of mRNA splicing, via spliceosome (GO:0048024)2.28380905
143transmission of nerve impulse (GO:0019226)2.27836004
144chromatin assembly or disassembly (GO:0006333)2.27193714
145kinetochore assembly (GO:0051382)2.26919408
146histone H2A monoubiquitination (GO:0035518)2.26372677
147glutamate secretion (GO:0014047)2.25700330
148negative regulation of chromatin modification (GO:1903309)2.25268959
149stress granule assembly (GO:0034063)2.24811117
150negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.24344430
151positive regulation of chromosome segregation (GO:0051984)2.23507542
152cerebellar Purkinje cell differentiation (GO:0021702)2.23138539
153presynaptic membrane assembly (GO:0097105)2.21935794
154histone H3-K9 methylation (GO:0051567)2.20200461
155protein-DNA complex disassembly (GO:0032986)2.20024263
156nucleosome disassembly (GO:0006337)2.20024263
157nucleosome organization (GO:0034728)2.20017134
158DNA duplex unwinding (GO:0032508)2.19609905
159DNA geometric change (GO:0032392)2.19211785
160DNA replication-independent nucleosome assembly (GO:0006336)2.18760566
161DNA replication-independent nucleosome organization (GO:0034724)2.18760566
162mitotic metaphase plate congression (GO:0007080)2.18508027
163synaptic transmission, glutamatergic (GO:0035249)2.17646742
164regulation of long-term neuronal synaptic plasticity (GO:0048169)2.16938597

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.41260471
2EZH2_22144423_ChIP-Seq_EOC_Human5.32094176
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.68083782
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.19184937
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.18041873
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.81124549
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.72352203
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.68515054
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.51127525
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.41246523
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.34202714
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.23157063
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.06948023
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06813900
15* FUS_26573619_Chip-Seq_HEK293_Human2.06386325
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.02203290
17GBX2_23144817_ChIP-Seq_PC3_Human1.99958248
18EST1_17652178_ChIP-ChIP_JURKAT_Human1.93731789
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.84718980
20KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.80621889
21KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.80621889
22KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.80621889
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.80613627
24CREB1_15753290_ChIP-ChIP_HEK293T_Human1.75286054
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.73258763
26ZNF274_21170338_ChIP-Seq_K562_Hela1.70934574
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70820288
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.69589474
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.69432560
30IGF1R_20145208_ChIP-Seq_DFB_Human1.68198930
31REST_21632747_ChIP-Seq_MESCs_Mouse1.67476447
32NANOG_16153702_ChIP-ChIP_HESCs_Human1.65199353
33HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.64994370
34JARID2_20064375_ChIP-Seq_MESCs_Mouse1.64180889
35FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.61584132
36ELK1_19687146_ChIP-ChIP_HELA_Human1.59830613
37NELFA_20434984_ChIP-Seq_ESCs_Mouse1.58820958
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58712572
39* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.58053570
40BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.57136212
41TTF2_22483619_ChIP-Seq_HELA_Human1.57066037
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.56902453
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56311501
44HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.54853606
45MYC_18940864_ChIP-ChIP_HL60_Human1.52016404
46RNF2_27304074_Chip-Seq_NSC_Mouse1.50862230
47MYC_18358816_ChIP-ChIP_MESCs_Mouse1.50687184
48EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.49441302
49EWS_26573619_Chip-Seq_HEK293_Human1.47833664
50CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.47689830
51GABP_17652178_ChIP-ChIP_JURKAT_Human1.46885161
52POU3F2_20337985_ChIP-ChIP_501MEL_Human1.46103025
53THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43242775
54EZH2_27304074_Chip-Seq_ESCs_Mouse1.41653482
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.41302606
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.41214746
57TAF15_26573619_Chip-Seq_HEK293_Human1.40721878
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.40484990
59XRN2_22483619_ChIP-Seq_HELA_Human1.36676795
60CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36560200
61* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.35024861
62PKCTHETA_26484144_Chip-Seq_BREAST_Human1.32514055
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.31663894
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30479152
65GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.28942966
66ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28400337
67NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.27758256
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.26190222
69ETS1_20019798_ChIP-Seq_JURKAT_Human1.25983855
70RNF2_27304074_Chip-Seq_ESCs_Mouse1.25323102
71* FOXP3_21729870_ChIP-Seq_TREG_Human1.24980669
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.24547502
73POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24310148
74SOX2_16153702_ChIP-ChIP_HESCs_Human1.24256865
75CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24204705
76SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.21311887
77RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20457240
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20299927
79IRF1_19129219_ChIP-ChIP_H3396_Human1.18823892
80REST_18959480_ChIP-ChIP_MESCs_Mouse1.16664179
81EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16298386
82RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16298386
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15282468
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15282468
85POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14696832
86* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.14408715
87GATA1_26923725_Chip-Seq_HPCs_Mouse1.14087383
88FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14003221
89E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13659750
90FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.12413412
91TCF3_18692474_ChIP-Seq_MEFs_Mouse1.12157625
92DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.11626148
93TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11545499
94SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.10837354
95NANOG_18555785_ChIP-Seq_MESCs_Mouse1.10418770
96SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.09923059
97TCF3_18692474_ChIP-Seq_MESCs_Mouse1.09817022
98RING1B_27294783_Chip-Seq_NPCs_Mouse1.09469566
99BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09182863
100* SOX9_26525672_Chip-Seq_HEART_Mouse1.08591813
101ZFP281_27345836_Chip-Seq_ESCs_Mouse1.08253606
102AR_21909140_ChIP-Seq_LNCAP_Human1.07671084
103STAT3_23295773_ChIP-Seq_U87_Human1.07584236
104RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.06357417
105YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06290407
106FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.06268718
107SMAD4_21799915_ChIP-Seq_A2780_Human1.06027450
108* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05872728
109YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05180698
110* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04413595
111CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.04145697
112VDR_23849224_ChIP-Seq_CD4+_Human1.03766413
113ZFP281_18757296_ChIP-ChIP_E14_Mouse1.03584794
114ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.01125523
115SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00414436
116POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.00069345
117E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99548075
118JARID2_20075857_ChIP-Seq_MESCs_Mouse0.98500433
119P300_19829295_ChIP-Seq_ESCs_Human0.98459077
120SMAD3_21741376_ChIP-Seq_EPCs_Human0.98170780
121TCF4_23295773_ChIP-Seq_U87_Human0.96992028
122SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.96131774
123ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95271109
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95264410
125TBX3_20139965_ChIP-Seq_ESCs_Mouse0.95262023
126ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95235776
127TBX3_20139965_ChIP-Seq_MESCs_Mouse0.94598618
128POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.92758705
129PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92557678
130KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91967836
131TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91512958
132FLI1_27457419_Chip-Seq_LIVER_Mouse0.91129528
133STAT6_21828071_ChIP-Seq_BEAS2B_Human0.90938216
134EED_16625203_ChIP-ChIP_MESCs_Mouse0.90931741
135PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.90275332
136EZH2_27294783_Chip-Seq_ESCs_Mouse0.89907566
137AR_19668381_ChIP-Seq_PC3_Human0.89831137
138SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.89628337
139NANOG_21062744_ChIP-ChIP_HESCs_Human0.89406102
140GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88880586
141PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.88494699
142* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88072954
143AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.87951160
144SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87810985
145MYCN_18555785_ChIP-Seq_MESCs_Mouse0.87399647
146RING1B_27294783_Chip-Seq_ESCs_Mouse0.85750556
147SOX2_21211035_ChIP-Seq_LN229_Gbm0.85623209
148YY1_21170310_ChIP-Seq_MESCs_Mouse0.84739479
149TP53_16413492_ChIP-PET_HCT116_Human0.84054620
150DROSHA_22980978_ChIP-Seq_HELA_Human0.83616744
151SMAD3_21741376_ChIP-Seq_ESCs_Human0.83421348
152MTF2_20144788_ChIP-Seq_MESCs_Mouse0.82972473
153JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.82094941
154NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.81515284

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.33712554
2MP0003880_abnormal_central_pattern2.89505835
3MP0008877_abnormal_DNA_methylation2.84472561
4MP0003787_abnormal_imprinting2.73883075
5MP0003123_paternal_imprinting2.50791277
6MP0003121_genomic_imprinting2.44269786
7MP0003635_abnormal_synaptic_transmissio2.33637031
8MP0003941_abnormal_skin_development2.16485253
9MP0000778_abnormal_nervous_system2.12403568
10MP0004270_analgesia2.09569925
11MP0008057_abnormal_DNA_replication2.03878833
12MP0010094_abnormal_chromosome_stability1.97813673
13MP0009672_abnormal_birth_weight1.94816715
14MP0005423_abnormal_somatic_nervous1.94599496
15MP0002063_abnormal_learning/memory/cond1.94096405
16MP0003122_maternal_imprinting1.92410237
17MP0005499_abnormal_olfactory_system1.89584173
18MP0005394_taste/olfaction_phenotype1.89584173
19MP0009379_abnormal_foot_pigmentation1.79643859
20MP0009745_abnormal_behavioral_response1.73885412
21MP0002653_abnormal_ependyma_morphology1.72835261
22MP0008789_abnormal_olfactory_epithelium1.71628217
23MP0003890_abnormal_embryonic-extraembry1.70228746
24MP0003567_abnormal_fetal_cardiomyocyte1.69926039
25MP0003111_abnormal_nucleus_morphology1.67822502
26MP0003136_yellow_coat_color1.66924125
27MP0000537_abnormal_urethra_morphology1.66422581
28MP0006072_abnormal_retinal_apoptosis1.62456595
29MP0006292_abnormal_olfactory_placode1.61324656
30MP0002697_abnormal_eye_size1.56837702
31MP0003861_abnormal_nervous_system1.54660625
32MP0002184_abnormal_innervation1.51743016
33MP0001486_abnormal_startle_reflex1.50471444
34MP0002064_seizures1.48654894
35MP0009046_muscle_twitch1.47584582
36MP0002572_abnormal_emotion/affect_behav1.46875248
37MP0003077_abnormal_cell_cycle1.44880650
38MP0001968_abnormal_touch/_nociception1.43992007
39MP0001286_abnormal_eye_development1.42901938
40MP0002734_abnormal_mechanical_nocicepti1.40696366
41MP0000631_abnormal_neuroendocrine_gland1.40547652
42MP0000569_abnormal_digit_pigmentation1.40390402
43MP0005187_abnormal_penis_morphology1.39404741
44MP0002272_abnormal_nervous_system1.38842168
45MP0001984_abnormal_olfaction1.37778307
46MP0003718_maternal_effect1.37459544
47MP0002152_abnormal_brain_morphology1.36772200
48MP0002084_abnormal_developmental_patter1.36694542
49MP0003937_abnormal_limbs/digits/tail_de1.33203304
50MP0000955_abnormal_spinal_cord1.32246834
51MP0002938_white_spotting1.30692914
52MP0003283_abnormal_digestive_organ1.30603953
53MP0004957_abnormal_blastocyst_morpholog1.30413919
54MP0001529_abnormal_vocalization1.29262983
55MP0000428_abnormal_craniofacial_morphol1.27220625
56MP0003119_abnormal_digestive_system1.26812954
57MP0000566_synostosis1.26016265
58MP0004811_abnormal_neuron_physiology1.25710418
59* MP0003698_abnormal_male_reproductive1.22269134
60MP0002882_abnormal_neuron_morphology1.22034203
61MP0002557_abnormal_social/conspecific_i1.21454561
62MP0001929_abnormal_gametogenesis1.19805187
63MP0001177_atelectasis1.18214829
64MP0001188_hyperpigmentation1.17636101
65MP0004885_abnormal_endolymph1.17388385
66MP0002085_abnormal_embryonic_tissue1.17045173
67MP0004133_heterotaxia1.16944976
68MP0001730_embryonic_growth_arrest1.15737877
69MP0003693_abnormal_embryo_hatching1.15604050
70* MP0002210_abnormal_sex_determination1.14548619
71* MP0002067_abnormal_sensory_capabilities1.14333208
72MP0003315_abnormal_perineum_morphology1.13903693
73MP0005410_abnormal_fertilization1.10847446
74MP0010030_abnormal_orbit_morphology1.09407318
75MP0005386_behavior/neurological_phenoty1.08771194
76MP0004924_abnormal_behavior1.08771194
77MP0002102_abnormal_ear_morphology1.05716897
78MP0010307_abnormal_tumor_latency1.04943758
79MP0003984_embryonic_growth_retardation1.04844577
80MP0000350_abnormal_cell_proliferation1.04767318
81MP0002080_prenatal_lethality1.04596487
82MP0002736_abnormal_nociception_after1.04261242
83MP0008058_abnormal_DNA_repair1.03208702
84MP0003385_abnormal_body_wall1.02463520
85MP0002088_abnormal_embryonic_growth/wei1.02453350
86MP0008007_abnormal_cellular_replicative1.01204951
87MP0001299_abnormal_eye_distance/0.99838547
88MP0006276_abnormal_autonomic_nervous0.98761624
89MP0001485_abnormal_pinna_reflex0.98338804
90MP0001293_anophthalmia0.98274996
91MP0008932_abnormal_embryonic_tissue0.98232047
92* MP0001145_abnormal_male_reproductive0.98189485
93MP0002111_abnormal_tail_morphology0.98125800
94MP0001697_abnormal_embryo_size0.97291868
95MP0002233_abnormal_nose_morphology0.97010424
96MP0001440_abnormal_grooming_behavior0.96998107
97MP0001346_abnormal_lacrimal_gland0.95614773
98MP0005623_abnormal_meninges_morphology0.93895691
99MP0003938_abnormal_ear_development0.92640988
100MP0004197_abnormal_fetal_growth/weight/0.92573055
101MP0009703_decreased_birth_body0.92477532
102MP0009697_abnormal_copulation0.92328913
103MP0002752_abnormal_somatic_nervous0.91793281
104MP0002733_abnormal_thermal_nociception0.91286323
105MP0003755_abnormal_palate_morphology0.90819611
106* MP0000653_abnormal_sex_gland0.90274253
107MP0002092_abnormal_eye_morphology0.88889452
108MP0001672_abnormal_embryogenesis/_devel0.88477270
109MP0005380_embryogenesis_phenotype0.88477270
110* MP0002081_perinatal_lethality0.88121695
111* MP0002066_abnormal_motor_capabilities/c0.87721011
112MP0004233_abnormal_muscle_weight0.87478437
113MP0003935_abnormal_craniofacial_develop0.87414403
114MP0005551_abnormal_eye_electrophysiolog0.87021445
115MP0002396_abnormal_hematopoietic_system0.86205727
116MP0002751_abnormal_autonomic_nervous0.85973881
117MP0000049_abnormal_middle_ear0.85349659
118MP0002160_abnormal_reproductive_system0.84832702
119MP0003115_abnormal_respiratory_system0.83529977
120MP0005253_abnormal_eye_physiology0.82844040
121MP0000313_abnormal_cell_death0.81760193
122MP0008569_lethality_at_weaning0.81483708
123MP0010234_abnormal_vibrissa_follicle0.81354328
124MP0005391_vision/eye_phenotype0.79845911
125MP0000579_abnormal_nail_morphology0.76269034
126* MP0000432_abnormal_head_morphology0.71225983
127MP0010352_gastrointestinal_tract_polyps0.70891136

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.89590477
2Chromosomal breakage induced by crosslinking agents (HP:0003221)3.84708372
3Septo-optic dysplasia (HP:0100842)3.57810608
4Volvulus (HP:0002580)3.11481874
5Cortical dysplasia (HP:0002539)3.07175900
6Birth length less than 3rd percentile (HP:0003561)3.04109492
7Amyotrophic lateral sclerosis (HP:0007354)2.97265275
8Meckel diverticulum (HP:0002245)2.95349854
9Abnormality of chromosome stability (HP:0003220)2.89360609
10Abnormality of the ileum (HP:0001549)2.80115343
11Focal motor seizures (HP:0011153)2.79530989
12Abnormal lung lobation (HP:0002101)2.76603252
13Reticulocytopenia (HP:0001896)2.75508197
14Abnormality of the labia minora (HP:0012880)2.69356485
15Visual hallucinations (HP:0002367)2.66303296
16Hepatoblastoma (HP:0002884)2.64063585
17Aplasia/Hypoplasia of the uvula (HP:0010293)2.62280429
18Abnormality of the lower motor neuron (HP:0002366)2.61671783
19Papillary thyroid carcinoma (HP:0002895)2.48795620
20Rhabdomyosarcoma (HP:0002859)2.47218624
21Ectopic kidney (HP:0000086)2.45248350
22Focal seizures (HP:0007359)2.42888549
23Facial hemangioma (HP:0000329)2.40243835
24Abnormality of the septum pellucidum (HP:0007375)2.38118481
25Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.34372203
26Absent septum pellucidum (HP:0001331)2.32572921
27Increased nuchal translucency (HP:0010880)2.31725880
28Triphalangeal thumb (HP:0001199)2.23412754
29Stenosis of the external auditory canal (HP:0000402)2.19067863
30Abnormality of the preputium (HP:0100587)2.16095199
31Small intestinal stenosis (HP:0012848)2.14669466
32Duodenal stenosis (HP:0100867)2.14669466
33Neoplasm of the adrenal cortex (HP:0100641)2.14051904
34Epileptic encephalopathy (HP:0200134)2.13065645
35Supernumerary spleens (HP:0009799)2.12442303
36Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.10683963
37Short 4th metacarpal (HP:0010044)2.10683963
38Astrocytoma (HP:0009592)2.10677886
39Abnormality of the astrocytes (HP:0100707)2.10677886
40Insidious onset (HP:0003587)2.10580668
41Termporal pattern (HP:0011008)2.10580668
42Abnormality of the duodenum (HP:0002246)2.08459527
43Absent radius (HP:0003974)2.08363526
44Medulloblastoma (HP:0002885)2.07831200
45Impulsivity (HP:0100710)2.06738645
46Maternal diabetes (HP:0009800)2.06108519
47Progressive cerebellar ataxia (HP:0002073)2.05309257
48Myokymia (HP:0002411)2.03346159
49Intestinal atresia (HP:0011100)2.02548651
50Molar tooth sign on MRI (HP:0002419)2.02388604
51Abnormality of midbrain morphology (HP:0002418)2.02388604
52Abnormality of the carotid arteries (HP:0005344)2.02363199
53Atonic seizures (HP:0010819)2.02235481
54Bilateral microphthalmos (HP:0007633)2.00574328
55Optic nerve hypoplasia (HP:0000609)1.98679928
56Neoplasm of the colon (HP:0100273)1.98679109
57Abnormal hair whorl (HP:0010721)1.98152736
58Aplasia/Hypoplasia of the sternum (HP:0006714)1.98005087
59Aplasia involving forearm bones (HP:0009822)1.96412307
60Absent forearm bone (HP:0003953)1.96412307
61Inappropriate behavior (HP:0000719)1.94829037
62Oligodactyly (hands) (HP:0001180)1.94316693
63Obsessive-compulsive behavior (HP:0000722)1.94088425
64Horseshoe kidney (HP:0000085)1.93993051
65Sloping forehead (HP:0000340)1.93935488
66Chronic bronchitis (HP:0004469)1.93476450
67Spastic diplegia (HP:0001264)1.92998018
68Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.92943165
69Dynein arm defect of respiratory motile cilia (HP:0012255)1.92798938
70Absent/shortened dynein arms (HP:0200106)1.92798938
71Ependymoma (HP:0002888)1.92798265
72Genetic anticipation (HP:0003743)1.92402144
73Shoulder girdle muscle weakness (HP:0003547)1.92278772
74Colon cancer (HP:0003003)1.90979684
75Abnormal respiratory motile cilium physiology (HP:0012261)1.90769703
76Broad-based gait (HP:0002136)1.90686982
77Renal duplication (HP:0000075)1.90343811
78Embryonal neoplasm (HP:0002898)1.89907625
79Aqueductal stenosis (HP:0002410)1.89771256
80Anophthalmia (HP:0000528)1.89622462
81Gaze-evoked nystagmus (HP:0000640)1.89553865
82Oligodactyly (HP:0012165)1.88641217
83Excessive salivation (HP:0003781)1.88000745
84Drooling (HP:0002307)1.88000745
85Pointed chin (HP:0000307)1.87763861
86Hyperglycinemia (HP:0002154)1.87502544
87Heterotopia (HP:0002282)1.87173959
88Agnosia (HP:0010524)1.87078358
89High anterior hairline (HP:0009890)1.86510546
90Duplication of thumb phalanx (HP:0009942)1.85268560
91Sacral dimple (HP:0000960)1.83883426
92Abnormality of cochlea (HP:0000375)1.83437368
93Neoplasm of striated muscle (HP:0009728)1.82765464
94Insomnia (HP:0100785)1.82732399
95Deep palmar crease (HP:0006191)1.82261165
96Nephroblastoma (Wilms tumor) (HP:0002667)1.80915676
97Abnormality of ocular smooth pursuit (HP:0000617)1.80307577
98Neoplasm of the oral cavity (HP:0100649)1.79557894
99Impaired vibration sensation in the lower limbs (HP:0002166)1.79148143
100Choanal stenosis (HP:0000452)1.78991250
101Myelodysplasia (HP:0002863)1.78483100
102Gastrointestinal atresia (HP:0002589)1.78371500
103Trigonocephaly (HP:0000243)1.77575358
104Breast aplasia (HP:0100783)1.77368061
105Absence seizures (HP:0002121)1.77000823
106Cutaneous syndactyly (HP:0012725)1.76888634
107Nephronophthisis (HP:0000090)1.75976568
108Absent speech (HP:0001344)1.75798026
109Impaired smooth pursuit (HP:0007772)1.75369016
110Abnormality of the corticospinal tract (HP:0002492)1.73994448
111Abnormality of cells of the erythroid lineage (HP:0012130)1.73879092
112Cutaneous finger syndactyly (HP:0010554)1.73747233
113Abnormality of chromosome segregation (HP:0002916)1.73468328
114Aplasia/Hypoplasia of the breasts (HP:0010311)1.73378754
115Overriding aorta (HP:0002623)1.71460818
116Multiple enchondromatosis (HP:0005701)1.71247014
117Atrophy/Degeneration involving motor neurons (HP:0007373)1.71098099
118Embryonal renal neoplasm (HP:0011794)1.70732005
119Glioma (HP:0009733)1.70583743
120Protruding tongue (HP:0010808)1.70144179
121Holoprosencephaly (HP:0001360)1.65891706
122Cafe-au-lait spot (HP:0000957)1.64847962
123Abnormality of the phalanges of the hallux (HP:0010057)1.64807173
124Atresia of the external auditory canal (HP:0000413)1.63617640
125Aplasia/Hypoplasia of the patella (HP:0006498)1.63534708
126Truncal obesity (HP:0001956)1.63414243
127Pelvic girdle muscle weakness (HP:0003749)1.63376793
128Febrile seizures (HP:0002373)1.62907108
129Macroorchidism (HP:0000053)1.62892769
130Thyroid carcinoma (HP:0002890)1.60903982
131Rhinitis (HP:0012384)1.60652974
132Urinary bladder sphincter dysfunction (HP:0002839)1.60313848
133Microglossia (HP:0000171)1.60274222
134Urinary urgency (HP:0000012)1.59858699
135Absent thumb (HP:0009777)1.59770559
136Biliary tract neoplasm (HP:0100574)1.59546308
137Gastroesophageal reflux (HP:0002020)1.58527224
138Renovascular hypertension (HP:0100817)1.57041641
139Degeneration of the lateral corticospinal tracts (HP:0002314)1.56804674
140Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.56804674
141Amblyopia (HP:0000646)1.56449850
142Abnormal ciliary motility (HP:0012262)1.56398088
143Midline defect of the nose (HP:0004122)1.56026471
144Macrocytic anemia (HP:0001972)1.55998220
145Gastrointestinal carcinoma (HP:0002672)1.55700488
146Malignant gastrointestinal tract tumors (HP:0006749)1.55700488
147Ankyloglossia (HP:0010296)1.55681781
148Morphological abnormality of the inner ear (HP:0011390)1.55524396
149Hyperacusis (HP:0010780)1.55373633
150Dialeptic seizures (HP:0011146)1.55313725
151Abnormal respiratory motile cilium morphology (HP:0005938)1.55219062
152Abnormal respiratory epithelium morphology (HP:0012253)1.55219062
153Dandy-Walker malformation (HP:0001305)1.54783613
154Abnormality of the diencephalon (HP:0010662)1.54700166
155Facial cleft (HP:0002006)1.54629579
156Abnormality of abdominal situs (HP:0011620)1.54041136
157Abdominal situs inversus (HP:0003363)1.54041136
158Neoplasm of the small intestine (HP:0100833)1.53805785
159Carpal bone hypoplasia (HP:0001498)1.53802587
160Abnormal number of incisors (HP:0011064)1.53266243
161Sandal gap (HP:0001852)1.53068543
162Preaxial hand polydactyly (HP:0001177)1.52693734
163Rib fusion (HP:0000902)1.52581005
164Gait imbalance (HP:0002141)1.52535332
165Hemivertebrae (HP:0002937)1.52041026
166Patellar aplasia (HP:0006443)1.51816948
167Abnormality of the 4th metacarpal (HP:0010012)1.50463442
168Tracheoesophageal fistula (HP:0002575)1.50366456
169Abnormality of the hip-girdle musculature (HP:0001445)1.49889354
170Abnormality of the musculature of the pelvis (HP:0001469)1.49889354
171Bifid tongue (HP:0010297)1.49576544
172Esophageal atresia (HP:0002032)1.47925685
173Dysdiadochokinesis (HP:0002075)1.47163853
174Attention deficit hyperactivity disorder (HP:0007018)1.46870602

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK3.48702698
2* CDC72.65415203
3NTRK32.62137818
4TAF12.61363765
5MARK12.44763429
6MAP3K42.35865813
7MAP3K92.19853939
8EPHA42.19663552
9VRK22.13906112
10CDK122.13085284
11ZAK2.09521381
12LATS22.08019358
13NEK22.02982651
14KSR12.01766396
15MINK11.79247316
16SRPK11.73609420
17LATS11.72575561
18PRKD31.71713240
19NTRK21.68549723
20TYRO31.67161169
21PAK61.63233314
22NUAK11.61271733
23MKNK11.59604217
24PLK21.41379739
25BRSK21.39412093
26VRK11.39123502
27MKNK21.38818172
28MAP2K71.36979225
29KSR21.35810466
30PBK1.32794252
31WEE11.31600085
32TTK1.30234014
33SIK21.28910421
34MAPK131.27302573
35PLK31.24882877
36CHEK21.20275477
37ERBB31.19792606
38BRD41.16890410
39PLK41.16517453
40CHEK11.15130458
41NEK11.14324424
42UHMK11.11228778
43TRIM281.09859634
44CSNK1G21.08837688
45ATR1.04660755
46STK38L1.03127601
47DYRK1A0.99174213
48PLK10.98849795
49STK30.97255914
50ATM0.96947455
51MAP2K40.94287418
52STK380.94011083
53CSNK1G30.93908651
54RPS6KA40.93473226
55ALK0.93119117
56PDK40.89623688
57PDK30.89623688
58CSNK1A1L0.87114955
59CDK20.87026204
60CCNB10.85413183
61CDK180.84736877
62CDK150.84421543
63CDK140.84389229
64PASK0.83347949
65CDK50.82248128
66SCYL20.82162848
67CSNK1E0.81562636
68EEF2K0.81518842
69CDK190.81323870
70CDK10.80493732
71MELK0.79726835
72BMPR1B0.79567683
73FGFR20.79054022
74RPS6KB20.78917270
75CDK11A0.78667161
76EIF2AK20.78215359
77DMPK0.73671110
78MAPK100.73020992
79CDK70.72505742
80BRSK10.72184099
81ICK0.71372890
82CAMK1G0.70239094
83CSNK1D0.69104874
84BCR0.69044917
85DYRK20.68902497
86CSNK1G10.68162479
87CASK0.65925791
88RAF10.64100377
89WNK10.63527509
90MAP3K100.63454262
91STK110.63339572
92MAP3K60.62979169
93RET0.62469405
94PRKDC0.62314865
95CDK80.60874760
96NLK0.60669279
97AURKB0.60324040
98SMG10.59959644
99CDK40.59460281
100BRAF0.58929561
101STK240.58878998
102NME10.57634882
103EIF2AK30.57566543
104GSK3B0.57488048
105BUB10.56677138
106CAMKK10.56137002
107TSSK60.53343043
108PRKCG0.53116376
109CDK90.52774376
110NTRK10.52386610
111DAPK10.52237811
112MAPK140.52171679
113CDK30.51949685
114CSNK2A20.51745282
115WNK30.50895813
116PDGFRA0.49268201
117ACVR1B0.48965327
118MST40.47320783
119STK40.44828812
120TNIK0.44807454
121AURKA0.44644885
122STK160.44424226
123CDK60.44277203
124MARK20.42913949
125SGK10.42867623
126FGFR10.42179500
127CSNK2A10.41976372
128DYRK30.41915418
129RPS6KA30.41026389
130CAMK1D0.38900800
131YES10.35686019
132SGK4940.33021204
133SGK2230.33021204

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.51044579
2Long-term potentiation_Homo sapiens_hsa047202.31854270
3Ribosome_Homo sapiens_hsa030102.10490193
4Oocyte meiosis_Homo sapiens_hsa041142.07125382
5mRNA surveillance pathway_Homo sapiens_hsa030152.02101086
6Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.00236240
7RNA polymerase_Homo sapiens_hsa030201.98858504
8Amphetamine addiction_Homo sapiens_hsa050311.94342391
9One carbon pool by folate_Homo sapiens_hsa006701.89375151
10Cell cycle_Homo sapiens_hsa041101.84049190
11Olfactory transduction_Homo sapiens_hsa047401.80310606
12Glutamatergic synapse_Homo sapiens_hsa047241.78767593
13Dopaminergic synapse_Homo sapiens_hsa047281.78508038
14Circadian entrainment_Homo sapiens_hsa047131.78301231
15Spliceosome_Homo sapiens_hsa030401.74262815
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.69096718
17Cysteine and methionine metabolism_Homo sapiens_hsa002701.63027031
18Morphine addiction_Homo sapiens_hsa050321.61865504
19Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.58499172
20RNA transport_Homo sapiens_hsa030131.58356065
21Synaptic vesicle cycle_Homo sapiens_hsa047211.56588937
22GABAergic synapse_Homo sapiens_hsa047271.56083193
23Long-term depression_Homo sapiens_hsa047301.55745061
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.48311451
25Mismatch repair_Homo sapiens_hsa034301.46254140
26Protein export_Homo sapiens_hsa030601.42636936
27DNA replication_Homo sapiens_hsa030301.41544923
28Alcoholism_Homo sapiens_hsa050341.38917590
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.33562066
30Axon guidance_Homo sapiens_hsa043601.33352524
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.30994926
32Selenocompound metabolism_Homo sapiens_hsa004501.29753907
33Phototransduction_Homo sapiens_hsa047441.28701772
34RNA degradation_Homo sapiens_hsa030181.27080034
35Cholinergic synapse_Homo sapiens_hsa047251.26698499
36Glioma_Homo sapiens_hsa052141.26438617
37Wnt signaling pathway_Homo sapiens_hsa043101.24987647
38Fanconi anemia pathway_Homo sapiens_hsa034601.24477054
39Dorso-ventral axis formation_Homo sapiens_hsa043201.23458985
40Cocaine addiction_Homo sapiens_hsa050301.23037559
41Estrogen signaling pathway_Homo sapiens_hsa049151.22979799
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.21596004
43Colorectal cancer_Homo sapiens_hsa052101.20768939
44Oxytocin signaling pathway_Homo sapiens_hsa049211.20262360
45Gap junction_Homo sapiens_hsa045401.20078684
46Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.18440087
47Melanogenesis_Homo sapiens_hsa049161.17425497
48Serotonergic synapse_Homo sapiens_hsa047261.17293681
49Taste transduction_Homo sapiens_hsa047421.16979780
50Pyrimidine metabolism_Homo sapiens_hsa002401.16720343
51Renin secretion_Homo sapiens_hsa049241.16184797
52Salivary secretion_Homo sapiens_hsa049701.13987337
53Basal transcription factors_Homo sapiens_hsa030221.13980526
54Hedgehog signaling pathway_Homo sapiens_hsa043401.11427550
55Insulin secretion_Homo sapiens_hsa049111.09867130
56Basal cell carcinoma_Homo sapiens_hsa052171.09342081
57GnRH signaling pathway_Homo sapiens_hsa049121.09273090
58Endometrial cancer_Homo sapiens_hsa052131.08638573
59Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.05658102
60Aldosterone synthesis and secretion_Homo sapiens_hsa049251.04974109
61ErbB signaling pathway_Homo sapiens_hsa040121.04067196
62Hippo signaling pathway_Homo sapiens_hsa043901.03228151
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03032016
64Proteasome_Homo sapiens_hsa030501.02625090
65Gastric acid secretion_Homo sapiens_hsa049711.02279928
66Purine metabolism_Homo sapiens_hsa002301.01818647
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01626888
68Biosynthesis of amino acids_Homo sapiens_hsa012300.99544210
69Non-small cell lung cancer_Homo sapiens_hsa052230.99301840
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.97781497
71Nucleotide excision repair_Homo sapiens_hsa034200.96058406
72Homologous recombination_Homo sapiens_hsa034400.95678015
73mTOR signaling pathway_Homo sapiens_hsa041500.95625322
74MicroRNAs in cancer_Homo sapiens_hsa052060.94934437
75Lysine degradation_Homo sapiens_hsa003100.93920899
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93193693
77cAMP signaling pathway_Homo sapiens_hsa040240.90930371
78Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90435215
79p53 signaling pathway_Homo sapiens_hsa041150.90356204
80Vitamin B6 metabolism_Homo sapiens_hsa007500.90118811
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89797606
82Calcium signaling pathway_Homo sapiens_hsa040200.88749186
83Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88476280
84Propanoate metabolism_Homo sapiens_hsa006400.88044552
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87448310
86VEGF signaling pathway_Homo sapiens_hsa043700.86679822
87Pyruvate metabolism_Homo sapiens_hsa006200.86080328
88Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.85954861
89Renal cell carcinoma_Homo sapiens_hsa052110.84972188
90Non-homologous end-joining_Homo sapiens_hsa034500.84301175
91Huntingtons disease_Homo sapiens_hsa050160.82274116
92Thyroid cancer_Homo sapiens_hsa052160.78961754
93Choline metabolism in cancer_Homo sapiens_hsa052310.78412273
94MAPK signaling pathway_Homo sapiens_hsa040100.77485206
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.73918628
96Systemic lupus erythematosus_Homo sapiens_hsa053220.71839478
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.71782700
98Parkinsons disease_Homo sapiens_hsa050120.71242039
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70716566
100Steroid biosynthesis_Homo sapiens_hsa001000.70319734
101Glucagon signaling pathway_Homo sapiens_hsa049220.69872817
102TGF-beta signaling pathway_Homo sapiens_hsa043500.67794869
103Base excision repair_Homo sapiens_hsa034100.66285431
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.63827806
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63529518
106Type II diabetes mellitus_Homo sapiens_hsa049300.62939350
107Chronic myeloid leukemia_Homo sapiens_hsa052200.62867760
108Prostate cancer_Homo sapiens_hsa052150.62229144
109Tight junction_Homo sapiens_hsa045300.61529490
110Folate biosynthesis_Homo sapiens_hsa007900.61509382
111Pancreatic cancer_Homo sapiens_hsa052120.60193678
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58905685
113Viral carcinogenesis_Homo sapiens_hsa052030.58312818
114Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.57082274
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.56990682
116HTLV-I infection_Homo sapiens_hsa051660.56629127
117Inositol phosphate metabolism_Homo sapiens_hsa005620.56000991
118Ras signaling pathway_Homo sapiens_hsa040140.55973801
119Rap1 signaling pathway_Homo sapiens_hsa040150.55817101
120Melanoma_Homo sapiens_hsa052180.55130088
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54189284
122Thyroid hormone synthesis_Homo sapiens_hsa049180.53677505
1232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52797526
124Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.50660680
125Adherens junction_Homo sapiens_hsa045200.49934102
126Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.49910643
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.49723870
128Notch signaling pathway_Homo sapiens_hsa043300.49180744
129Carbon metabolism_Homo sapiens_hsa012000.46494692
130Cardiac muscle contraction_Homo sapiens_hsa042600.41890816
131Oxidative phosphorylation_Homo sapiens_hsa001900.41004088
132Epstein-Barr virus infection_Homo sapiens_hsa051690.35825249
133Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32535246
134Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.29483895
135Alzheimers disease_Homo sapiens_hsa050100.27808650
136Pathways in cancer_Homo sapiens_hsa052000.22341459
137Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.19817696
138Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18814091

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