PSMA5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.59582539
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.42967886
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.05443494
4ATP synthesis coupled proton transport (GO:0015986)5.05443494
5* negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.94011640
6ribosomal small subunit assembly (GO:0000028)4.71406073
7* positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.61183373
8* negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.53775593
9* negative regulation of ligase activity (GO:0051352)4.53775593
10maturation of SSU-rRNA (GO:0030490)4.53219696
11* regulation of cellular amino acid metabolic process (GO:0006521)4.52798646
12* regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.50993183
13cullin deneddylation (GO:0010388)4.48606483
14* DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.42570404
15* anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.42490703
16* signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.34348554
17* intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.34348554
18* signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.30853060
19* signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.30853060
20* signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.30853060
21ribosomal small subunit biogenesis (GO:0042274)4.28515125
22protein neddylation (GO:0045116)4.28387946
23* antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:4.28275223
24protein deneddylation (GO:0000338)4.23027581
25* signal transduction involved in DNA damage checkpoint (GO:0072422)4.19613242
26* signal transduction involved in DNA integrity checkpoint (GO:0072401)4.19613242
27formation of translation preinitiation complex (GO:0001731)4.16590261
28* signal transduction involved in cell cycle checkpoint (GO:0072395)4.14728196
297-methylguanosine mRNA capping (GO:0006370)4.12541844
30establishment of protein localization to mitochondrial membrane (GO:0090151)4.09153565
31ribosomal large subunit biogenesis (GO:0042273)4.07408452
327-methylguanosine RNA capping (GO:0009452)4.06698213
33RNA capping (GO:0036260)4.06698213
34viral transcription (GO:0019083)4.04306940
35termination of RNA polymerase III transcription (GO:0006386)4.03389072
36transcription elongation from RNA polymerase III promoter (GO:0006385)4.03389072
37chaperone-mediated protein transport (GO:0072321)4.03318015
38* antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)4.02459146
39translational termination (GO:0006415)4.02035542
40* positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.96820102
41cotranslational protein targeting to membrane (GO:0006613)3.86193311
42SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.84885918
43* positive regulation of ligase activity (GO:0051351)3.82146734
44mitotic metaphase plate congression (GO:0007080)3.82096542
45protein targeting to ER (GO:0045047)3.78613442
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.77429039
47mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.74968058
48mitochondrial respiratory chain complex I assembly (GO:0032981)3.74968058
49NADH dehydrogenase complex assembly (GO:0010257)3.74968058
50DNA strand elongation involved in DNA replication (GO:0006271)3.73381115
51L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.69932926
52translation (GO:0006412)3.68491677
53DNA deamination (GO:0045006)3.66474032
54telomere maintenance via semi-conservative replication (GO:0032201)3.65225203
55establishment of integrated proviral latency (GO:0075713)3.65157769
56protein localization to endoplasmic reticulum (GO:0070972)3.63064148
57translational elongation (GO:0006414)3.59683173
58establishment of protein localization to endoplasmic reticulum (GO:0072599)3.58222128
59DNA replication checkpoint (GO:0000076)3.57786040
60ribonucleoprotein complex biogenesis (GO:0022613)3.57136464
61purine nucleobase biosynthetic process (GO:0009113)3.56941406
62translational initiation (GO:0006413)3.56303488
63DNA strand elongation (GO:0022616)3.54452740
64spliceosomal snRNP assembly (GO:0000387)3.53640727
65* regulation of ubiquitin-protein transferase activity (GO:0051438)3.52660871
66nucleobase biosynthetic process (GO:0046112)3.50715052
67respiratory electron transport chain (GO:0022904)3.50149394
68CENP-A containing nucleosome assembly (GO:0034080)3.48790056
69regulation of mitochondrial translation (GO:0070129)3.46433547
70* positive regulation of cell cycle arrest (GO:0071158)3.45151751
71transcription-coupled nucleotide-excision repair (GO:0006283)3.44942645
72* DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.44441234
73protein complex biogenesis (GO:0070271)3.43014835
74nucleobase-containing small molecule interconversion (GO:0015949)3.42509386
75* regulation of ligase activity (GO:0051340)3.42326265
76rRNA processing (GO:0006364)3.41952377
77electron transport chain (GO:0022900)3.41095558
78* regulation of cellular amine metabolic process (GO:0033238)3.38354133
79folic acid-containing compound biosynthetic process (GO:0009396)3.37544975
80transcription elongation from RNA polymerase I promoter (GO:0006362)3.36142158
81DNA replication initiation (GO:0006270)3.35622813
82metaphase plate congression (GO:0051310)3.34688720
83* cell cycle G1/S phase transition (GO:0044843)3.34667632
84* G1/S transition of mitotic cell cycle (GO:0000082)3.34667632
85ribosome assembly (GO:0042255)3.34246187
86establishment of protein localization to mitochondrion (GO:0072655)3.33800352
87IMP biosynthetic process (GO:0006188)3.32482204
88deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.32452361
89pseudouridine synthesis (GO:0001522)3.32444209
90cellular component biogenesis (GO:0044085)3.32089041
91protein targeting to mitochondrion (GO:0006626)3.32051717
92nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31983135
93chromatin remodeling at centromere (GO:0031055)3.31380898
94rRNA methylation (GO:0031167)3.31291745
95viral mRNA export from host cell nucleus (GO:0046784)3.30931610
96* antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.29648953
97ribosome biogenesis (GO:0042254)3.28050454
98cellular protein complex disassembly (GO:0043624)3.27893495
99rRNA modification (GO:0000154)3.27027483
100telomere maintenance via recombination (GO:0000722)3.26845901
101rRNA metabolic process (GO:0016072)3.26351521
102pteridine-containing compound biosynthetic process (GO:0042559)3.25864569
103* negative regulation of protein ubiquitination (GO:0031397)3.25464483
104viral life cycle (GO:0019058)3.25214109
105mitochondrial respiratory chain complex assembly (GO:0033108)3.22284250
106GTP biosynthetic process (GO:0006183)3.21866503
107spliceosomal complex assembly (GO:0000245)3.21561645
108exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.21225451
109tRNA aminoacylation for protein translation (GO:0006418)3.19467830
110tRNA aminoacylation (GO:0043039)3.19072078
111amino acid activation (GO:0043038)3.19072078
112termination of RNA polymerase I transcription (GO:0006363)3.18601953
113establishment of viral latency (GO:0019043)3.18585323
114mitotic recombination (GO:0006312)3.18209127
115* negative regulation of protein modification by small protein conjugation or removal (GO:1903321)3.09199287
116protein localization to kinetochore (GO:0034501)3.06048796
117DNA catabolic process, exonucleolytic (GO:0000738)3.05473854
118protein localization to mitochondrion (GO:0070585)3.01011002
119nucleotide-excision repair, DNA gap filling (GO:0006297)3.00981328
120histone exchange (GO:0043486)2.99507450
121oxidative phosphorylation (GO:0006119)2.99498964
122respiratory chain complex IV assembly (GO:0008535)2.96913633
123telomere maintenance via telomere lengthening (GO:0010833)2.96431573
124protein maturation by protein folding (GO:0022417)2.96321298
125mitotic nuclear envelope disassembly (GO:0007077)2.96307405
126maturation of 5.8S rRNA (GO:0000460)2.92413846
127regulation of translational termination (GO:0006449)2.91984736
128tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.90751573
129RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.90751573
130protein localization to chromosome, centromeric region (GO:0071459)2.90598707
131establishment of chromosome localization (GO:0051303)2.88630646

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.12011937
2* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.90948061
3* GABP_17652178_ChIP-ChIP_JURKAT_Human4.45576302
4* EST1_17652178_ChIP-ChIP_JURKAT_Human4.35859058
5MYC_18555785_ChIP-Seq_MESCs_Mouse4.32285083
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.03741043
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.71337483
8* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.69473509
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.60666763
10* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.59812482
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.49583748
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.31637866
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.28814807
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.13521288
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.07732311
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.96663832
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91331119
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.85844413
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.82217636
20* VDR_23849224_ChIP-Seq_CD4+_Human2.77122422
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.76239146
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.73538596
23DCP1A_22483619_ChIP-Seq_HELA_Human2.46926404
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.40831393
25THAP11_20581084_ChIP-Seq_MESCs_Mouse2.40498341
26* ELK1_19687146_ChIP-ChIP_HELA_Human2.39387839
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.39269415
28XRN2_22483619_ChIP-Seq_HELA_Human2.38323200
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.36596086
30FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.29175605
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.26485212
32FOXP3_21729870_ChIP-Seq_TREG_Human2.25850535
33GABP_19822575_ChIP-Seq_HepG2_Human2.09698544
34TTF2_22483619_ChIP-Seq_HELA_Human2.04479354
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.02208140
36YY1_21170310_ChIP-Seq_MESCs_Mouse2.02063422
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.90054438
38HOXB4_20404135_ChIP-ChIP_EML_Mouse1.84730190
39ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.83631640
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.82244660
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80175202
42* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79053764
43MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.70004820
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69620190
45* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.69138670
46AR_21909140_ChIP-Seq_LNCAP_Human1.59494977
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56866651
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49866041
49FOXM1_23109430_ChIP-Seq_U2OS_Human1.49587719
50ELK1_22589737_ChIP-Seq_MCF10A_Human1.44819698
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.44540000
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.41939082
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38960361
54* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37454202
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35625741
56CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.31157924
57FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.30682671
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.30653595
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30488613
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.28944660
61ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.27723416
62MYC_18940864_ChIP-ChIP_HL60_Human1.24432009
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.24250318
64BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19280393
65CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.19204757
66PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.17372329
67CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.15912549
68* KDM5A_27292631_Chip-Seq_BREAST_Human1.14443133
69* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12960435
70SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.12356331
71* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10240071
72SOX17_20123909_ChIP-Seq_XEN_Mouse1.05316205
73* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.04301089
74TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.04011147
75CIITA_25753668_ChIP-Seq_RAJI_Human1.03913712
76DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03767363
77* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.03730474
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01819894
79* TFEB_21752829_ChIP-Seq_HELA_Human1.00363431
80* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98620980
81IRF1_19129219_ChIP-ChIP_H3396_Human0.96924988
82ELF5_23300383_ChIP-Seq_T47D_Human0.94267543
83* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88924069
84SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87813231
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.87768785
86ZNF263_19887448_ChIP-Seq_K562_Human0.87341540
87IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.85448243
88SPI1_23547873_ChIP-Seq_NB4_Human0.85268106
89ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.81774993
90SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81236956
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.80444402
92POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.79752671
93FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79543470
94TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.78378927
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78179178
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77506553
97HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.72678351
98TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.72449156
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.72288828
100CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.71324567
101ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.69579591
102BP1_19119308_ChIP-ChIP_Hs578T_Human0.69178145
103KLF4_18555785_ChIP-Seq_MESCs_Mouse0.69078379
104NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.69018747
105ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.68238954
106OCT4_18692474_ChIP-Seq_MEFs_Mouse0.67927783
107SOX2_18692474_ChIP-Seq_MEFs_Mouse0.66309355
108NANOG_16153702_ChIP-ChIP_HESCs_Human0.65497435
109* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.64570077
110STAT3_1855785_ChIP-Seq_MESCs_Mouse0.63972124
111* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.62613700
112* IRF8_21731497_ChIP-ChIP_J774_Mouse0.62536637
113CTCF_18555785_ChIP-Seq_MESCs_Mouse0.62345565

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.77198622
2MP0004957_abnormal_blastocyst_morpholog4.24666027
3MP0008057_abnormal_DNA_replication3.87239354
4MP0010094_abnormal_chromosome_stability3.63615364
5MP0008058_abnormal_DNA_repair3.54757421
6MP0003077_abnormal_cell_cycle3.42320781
7MP0003111_abnormal_nucleus_morphology3.16060841
8MP0003806_abnormal_nucleotide_metabolis3.11576383
9MP0008932_abnormal_embryonic_tissue3.08202396
10MP0001529_abnormal_vocalization2.86704787
11MP0009379_abnormal_foot_pigmentation2.63146089
12MP0003123_paternal_imprinting2.59238743
13MP0003718_maternal_effect2.48967519
14MP0008877_abnormal_DNA_methylation2.43736968
15MP0003186_abnormal_redox_activity2.39106970
16MP0008007_abnormal_cellular_replicative2.35287866
17MP0003941_abnormal_skin_development2.35194396
18MP0003786_premature_aging2.30763247
19MP0001905_abnormal_dopamine_level2.13241654
20MP0004147_increased_porphyrin_level1.90748047
21MP0010234_abnormal_vibrissa_follicle1.86814687
22MP0001730_embryonic_growth_arrest1.84542839
23MP0006036_abnormal_mitochondrial_physio1.81209355
24MP0006035_abnormal_mitochondrial_morpho1.68575006
25MP0002163_abnormal_gland_morphology1.68284535
26MP0009333_abnormal_splenocyte_physiolog1.60621153
27MP0010307_abnormal_tumor_latency1.58868876
28MP0002938_white_spotting1.55069852
29MP0009697_abnormal_copulation1.53394707
30MP0003315_abnormal_perineum_morphology1.49065249
31MP0003121_genomic_imprinting1.48544034
32MP0001727_abnormal_embryo_implantation1.45440845
33MP0000350_abnormal_cell_proliferation1.42960461
34MP0005408_hypopigmentation1.41397974
35MP0000372_irregular_coat_pigmentation1.38493147
36MP0008260_abnormal_autophagy1.25539123
37MP0002638_abnormal_pupillary_reflex1.23719393
38MP0010352_gastrointestinal_tract_polyps1.23409934
39MP0000313_abnormal_cell_death1.22177138
40MP0003122_maternal_imprinting1.21300525
41MP0002877_abnormal_melanocyte_morpholog1.20231140
42MP0003136_yellow_coat_color1.17994086
43MP0002160_abnormal_reproductive_system1.17894568
44MP0004133_heterotaxia1.14877527
45MP0002148_abnormal_hypersensitivity_rea1.14867704
46MP0002396_abnormal_hematopoietic_system1.14768803
47MP0002132_abnormal_respiratory_system1.14019955
48MP0001986_abnormal_taste_sensitivity1.13365219
49MP0001697_abnormal_embryo_size1.12743142
50MP0008875_abnormal_xenobiotic_pharmacok1.12658238
51MP0000358_abnormal_cell_content/1.11512998
52MP0009785_altered_susceptibility_to1.10601555
53MP0001542_abnormal_bone_strength1.09977896
54MP0001661_extended_life_span1.08244610
55MP0006292_abnormal_olfactory_placode1.06424972
56MP0001188_hyperpigmentation1.06342569
57MP0002080_prenatal_lethality1.05044488
58MP0003567_abnormal_fetal_cardiomyocyte1.04041420
59MP0002210_abnormal_sex_determination1.00626850
60MP0005501_abnormal_skin_physiology0.96755191
61MP0005379_endocrine/exocrine_gland_phen0.95792525
62MP0001881_abnormal_mammary_gland0.95457441
63MP0001853_heart_inflammation0.93713519
64MP0005171_absent_coat_pigmentation0.93318051
65MP0005389_reproductive_system_phenotype0.92984055
66MP0005075_abnormal_melanosome_morpholog0.92972237
67MP0002090_abnormal_vision0.92349814
68MP0002006_tumorigenesis0.91464576
69MP0006054_spinal_hemorrhage0.91411873
70MP0004142_abnormal_muscle_tone0.91262903
71MP0003221_abnormal_cardiomyocyte_apopto0.90013793
72MP0002102_abnormal_ear_morphology0.89161294
73MP0001835_abnormal_antigen_presentation0.89156922
74MP0003890_abnormal_embryonic-extraembry0.88614566
75MP0002139_abnormal_hepatobiliary_system0.88249902
76MP0005266_abnormal_metabolism0.88008397
77MP0005332_abnormal_amino_acid0.86915063
78MP0001764_abnormal_homeostasis0.86421119
79MP0006072_abnormal_retinal_apoptosis0.86090317
80MP0002751_abnormal_autonomic_nervous0.84389413
81MP0002019_abnormal_tumor_incidence0.83124007
82MP0001145_abnormal_male_reproductive0.82261152
83MP0001672_abnormal_embryogenesis/_devel0.80876215
84MP0005380_embryogenesis_phenotype0.80876215
85MP0003880_abnormal_central_pattern0.79573087
86MP0000490_abnormal_crypts_of0.79063234
87MP0005319_abnormal_enzyme/_coenzyme0.78051217
88MP0010030_abnormal_orbit_morphology0.77381359
89MP0003950_abnormal_plasma_membrane0.76546438
90MP0001293_anophthalmia0.75719762
91MP0002796_impaired_skin_barrier0.74973886
92MP0003984_embryonic_growth_retardation0.73092583
93MP0001119_abnormal_female_reproductive0.73044610
94MP0002084_abnormal_developmental_patter0.72800301
95MP0002085_abnormal_embryonic_tissue0.71385655
96MP0002086_abnormal_extraembryonic_tissu0.71233672
97MP0001485_abnormal_pinna_reflex0.70701620
98MP0001929_abnormal_gametogenesis0.70375899
99MP0002166_altered_tumor_susceptibility0.69400416
100MP0000015_abnormal_ear_pigmentation0.67893238
101MP0002088_abnormal_embryonic_growth/wei0.67865747
102MP0003699_abnormal_female_reproductive0.67642602
103MP0000653_abnormal_sex_gland0.67557457
104MP0003656_abnormal_erythrocyte_physiolo0.66829783
105MP0005330_cardiomyopathy0.66755603
106MP0006276_abnormal_autonomic_nervous0.66696616
107MP0002095_abnormal_skin_pigmentation0.66563437
108MP0005636_abnormal_mineral_homeostasis0.66411146
109MP0005410_abnormal_fertilization0.65568164
110MP0001666_abnormal_nutrient_absorption0.65303067
111MP0005671_abnormal_response_to0.64917750
112MP0002876_abnormal_thyroid_physiology0.63427656
113MP0008789_abnormal_olfactory_epithelium0.61371661
114MP0005384_cellular_phenotype0.61140152
115MP0002277_abnormal_respiratory_mucosa0.60585069
116MP0000689_abnormal_spleen_morphology0.60400688
117MP0005409_darkened_coat_color0.59640775
118MP0005376_homeostasis/metabolism_phenot0.58766206
119MP0004233_abnormal_muscle_weight0.58709390
120MP0002722_abnormal_immune_system0.58303103
121MP0002429_abnormal_blood_cell0.57659827
122MP0000647_abnormal_sebaceous_gland0.57095226
123MP0002398_abnormal_bone_marrow0.56745561
124MP0003937_abnormal_limbs/digits/tail_de0.56617551
125MP0005025_abnormal_response_to0.56043680
126MP0001919_abnormal_reproductive_system0.55070971
127MP0005451_abnormal_body_composition0.54579435
128MP0000749_muscle_degeneration0.52484749
129MP0000371_diluted_coat_color0.52253236
130MP0008873_increased_physiological_sensi0.52252399
131MP0001216_abnormal_epidermal_layer0.51847301
132MP0005395_other_phenotype0.51498626
133MP0001243_abnormal_dermal_layer0.51400976
134MP0000627_abnormal_mammary_gland0.51331397

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.56189452
2Mitochondrial inheritance (HP:0001427)5.03417963
3Abnormal mitochondria in muscle tissue (HP:0008316)4.93453475
4Increased serum pyruvate (HP:0003542)4.62465223
5Abnormality of glycolysis (HP:0004366)4.62465223
6Hepatocellular necrosis (HP:0001404)4.60469197
7Increased CSF lactate (HP:0002490)4.58833664
8Progressive macrocephaly (HP:0004481)4.44252144
9Increased hepatocellular lipid droplets (HP:0006565)4.35625814
10Acute encephalopathy (HP:0006846)4.32600540
11Abnormality of cells of the erythroid lineage (HP:0012130)4.03103070
12Birth length less than 3rd percentile (HP:0003561)4.01898811
13Hepatic necrosis (HP:0002605)3.99898243
14Lipid accumulation in hepatocytes (HP:0006561)3.83745831
15Abnormal number of erythroid precursors (HP:0012131)3.81735363
16Cerebral hypomyelination (HP:0006808)3.79487854
173-Methylglutaconic aciduria (HP:0003535)3.77995267
18Increased serum lactate (HP:0002151)3.56009697
19Reticulocytopenia (HP:0001896)3.48409028
20Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.42805436
21Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.41501861
22Decreased activity of mitochondrial respiratory chain (HP:0008972)3.41501861
23Renal Fanconi syndrome (HP:0001994)3.31308071
24Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.30447782
25Abnormality of methionine metabolism (HP:0010901)3.18947537
26Aplastic anemia (HP:0001915)3.18353791
27Breast hypoplasia (HP:0003187)3.15099385
28Exercise intolerance (HP:0003546)3.14357395
29Respiratory failure (HP:0002878)3.12457548
30Reduced antithrombin III activity (HP:0001976)3.11169846
31Chromosomal breakage induced by crosslinking agents (HP:0003221)3.07028547
32Exertional dyspnea (HP:0002875)3.03936565
33Macrocytic anemia (HP:0001972)3.02941512
34Leukodystrophy (HP:0002415)3.01282577
35Lactic acidosis (HP:0003128)2.92593428
36Rough bone trabeculation (HP:0100670)2.86928012
37Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.85960021
38Cerebral edema (HP:0002181)2.80923346
39Type I transferrin isoform profile (HP:0003642)2.73420229
40Cholecystitis (HP:0001082)2.72136519
41Abnormal gallbladder physiology (HP:0012438)2.72136519
42Oral leukoplakia (HP:0002745)2.68990311
43Increased intramyocellular lipid droplets (HP:0012240)2.64879017
44Abnormality of aspartate family amino acid metabolism (HP:0010899)2.59697485
45Parakeratosis (HP:0001036)2.59511028
46Pallor (HP:0000980)2.57774105
47Microvesicular hepatic steatosis (HP:0001414)2.57634114
48Respiratory difficulties (HP:0002880)2.56532371
49Generalized aminoaciduria (HP:0002909)2.52249584
50Carpal bone hypoplasia (HP:0001498)2.49648824
51Optic disc pallor (HP:0000543)2.48528561
52Abnormality of chromosome stability (HP:0003220)2.47918455
53Sparse eyelashes (HP:0000653)2.44806143
54Irregular epiphyses (HP:0010582)2.44491438
55CNS demyelination (HP:0007305)2.39204019
56Lethargy (HP:0001254)2.38415053
57Hypokinesia (HP:0002375)2.35205355
58Degeneration of anterior horn cells (HP:0002398)2.34481488
59Abnormality of the anterior horn cell (HP:0006802)2.34481488
60Aplasia/Hypoplasia of the uvula (HP:0010293)2.30382407
61Agnosia (HP:0010524)2.29354665
62CNS hypomyelination (HP:0003429)2.27388273
63Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26918396
64Methylmalonic acidemia (HP:0002912)2.25418873
65Megaloblastic anemia (HP:0001889)2.23980160
66Abnormal trabecular bone morphology (HP:0100671)2.23471050
67Emotional lability (HP:0000712)2.21732659
68Abnormality of sulfur amino acid metabolism (HP:0004339)2.21532393
69Postnatal microcephaly (HP:0005484)2.20745286
70Nausea (HP:0002018)2.16461970
71Premature graying of hair (HP:0002216)2.16013395
72Abnormality of aromatic amino acid family metabolism (HP:0004338)2.15706227
73Methylmalonic aciduria (HP:0012120)2.14600784
74Neoplasm of the adrenal gland (HP:0100631)2.12847958
75Abnormality of the heme biosynthetic pathway (HP:0010472)2.12593509
76Hypoplasia of the capital femoral epiphysis (HP:0003090)2.12407653
77Abnormality of serum amino acid levels (HP:0003112)2.11125483
78Abnormality of alanine metabolism (HP:0010916)2.10841488
79Hyperalaninemia (HP:0003348)2.10841488
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.10841488
81Duodenal stenosis (HP:0100867)2.10200010
82Small intestinal stenosis (HP:0012848)2.10200010
83Hypoglycemic coma (HP:0001325)2.10189553
84Increased muscle lipid content (HP:0009058)2.07832789
85Microretrognathia (HP:0000308)2.04488095
86Poor head control (HP:0002421)2.03039791
87Abnormalities of placenta or umbilical cord (HP:0001194)2.02844458
88Congenital ichthyosiform erythroderma (HP:0007431)2.02533624
89Posterior subcapsular cataract (HP:0007787)2.02082631
90Patellar aplasia (HP:0006443)1.99854796
91Sensory axonal neuropathy (HP:0003390)1.98145036
92Conjunctival hamartoma (HP:0100780)1.95965128
93Abnormality of renal resorption (HP:0011038)1.95462718
94Pancytopenia (HP:0001876)1.94963703
95Premature ovarian failure (HP:0008209)1.94572340
96Abnormal lung lobation (HP:0002101)1.90636210
97Glossoptosis (HP:0000162)1.89365703
98Secondary amenorrhea (HP:0000869)1.89009353
99Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.88965812
100Absent epiphyses (HP:0010577)1.88965812
101Abnormality of the umbilical cord (HP:0010881)1.87767375
102Aplasia/Hypoplasia of the patella (HP:0006498)1.87257946
103Trismus (HP:0000211)1.85937089
104Horseshoe kidney (HP:0000085)1.85634405
105Neuroendocrine neoplasm (HP:0100634)1.85414866
106Palpitations (HP:0001962)1.85166417
107Abnormality of the preputium (HP:0100587)1.84800249
108Chromsome breakage (HP:0040012)1.84369969
109Abnormality of placental membranes (HP:0011409)1.84355800
110Amniotic constriction ring (HP:0009775)1.84355800
111Type 2 muscle fiber atrophy (HP:0003554)1.84106855
112Colon cancer (HP:0003003)1.83448462
113Cellular immunodeficiency (HP:0005374)1.83111622
114Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.82997301
115Prolonged neonatal jaundice (HP:0006579)1.82863485
116Pancreatic cysts (HP:0001737)1.82576182
117Meckel diverticulum (HP:0002245)1.82145698
118Cleft eyelid (HP:0000625)1.81287206
119Absent thumb (HP:0009777)1.80102902
120Autoamputation (HP:0001218)1.78830785
121Pancreatic fibrosis (HP:0100732)1.78308541
122Cutaneous melanoma (HP:0012056)1.77837672
123Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.77276725
124Abnormal protein N-linked glycosylation (HP:0012347)1.77276725
125Abnormal protein glycosylation (HP:0012346)1.77276725
126Abnormal glycosylation (HP:0012345)1.77276725
127Bone marrow hypocellularity (HP:0005528)1.77214282
128Stenosis of the external auditory canal (HP:0000402)1.77039098
129Myelodysplasia (HP:0002863)1.76528079
130Absent radius (HP:0003974)1.75066630
131Multiple enchondromatosis (HP:0005701)1.73862085
132Abnormality of the ileum (HP:0001549)1.73128423
133Abnormality of the fetal cardiovascular system (HP:0010948)1.73034398
134Abnormal umbilical cord blood vessels (HP:0011403)1.73034398
135Single umbilical artery (HP:0001195)1.73034398

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.88476553
2EIF2AK13.75036887
3STK163.59425594
4VRK23.56550869
5WEE13.46486990
6PBK3.35597164
7EIF2AK32.81727662
8NME22.63727170
9TSSK62.51118973
10PLK42.38139379
11TRIM282.31752297
12VRK12.30894005
13SRPK12.29294933
14ACVR1B2.23973002
15CDC72.05321296
16NME12.00690927
17MST41.94431169
18BCR1.72796489
19TESK21.70294243
20BRSK21.68437221
21PIM21.66935558
22MKNK11.60310341
23PDK21.58532182
24PLK31.52655963
25ARAF1.39770259
26MAP3K121.37376215
27NUAK11.36724057
28PNCK1.34949585
29CCNB11.31796448
30LIMK11.31689508
31PLK11.27634178
32CDK191.23280988
33PASK1.20581804
34ZAK1.15769210
35BMPR1B1.13995762
36TLK11.12390155
37AURKA1.11388983
38BRAF1.09566487
39EIF2AK21.04150708
40NEK11.03909251
41BRSK11.02969437
42TTK1.00848542
43PLK21.00403853
44AURKB0.99248049
45DYRK20.96693282
46EPHA20.91502069
47MST1R0.91471158
48STK390.90624927
49TESK10.89440790
50TGFBR10.85808026
51OXSR10.85680306
52TAF10.84642703
53IRAK40.84196132
54ABL20.83844235
55ATR0.83443056
56BCKDK0.81271939
57OBSCN0.80441050
58MKNK20.78506862
59CSNK1G30.78217582
60MYLK0.77679348
61KDR0.77658885
62BMPR20.76644184
63CSNK2A10.76392104
64DYRK30.75709310
65RPS6KB20.75033623
66CSNK2A20.70664151
67CASK0.69202153
68PAK10.65501463
69STK100.65469294
70CHEK20.65168858
71AKT30.64096347
72CDK70.63825892
73RPS6KA50.60858820
74STK40.58556877
75ERBB40.57653475
76BLK0.55448124
77PAK40.55200989
78IRAK30.53933643
79CDK80.53116966
80CHEK10.53077841
81ALK0.52789966
82NEK20.51098673
83YES10.50375981
84ADRBK20.49986976
85CSNK1A1L0.48630960
86RPS6KA40.47447369
87MAP3K80.45653652
88STK30.44186455
89DAPK30.43832391
90GRK70.43323580
91TEC0.42627731
92TNIK0.41514195
93STK240.40237507
94CDK140.39945162
95MAP3K110.39679539
96ILK0.39569533
97SIK30.39376189
98CDK90.38151580
99MUSK0.37426115
100NEK60.37357195
101CSNK1G20.36775836
102MAPKAPK50.35409511
103SCYL20.35134168
104SMG10.34650026
105AKT20.34186912
106CDK180.34183840
107CSNK1G10.32872596
108PRKCI0.32468468
109DAPK10.32262779
110ATM0.31422366
111CDK11A0.31088390
112RAF10.29696219
113CDK150.29353447
114IKBKB0.28813914
115ERBB30.28610490
116WNK30.28522076
117ADRBK10.28521109
118CDK10.28400781
119CLK10.28242477
120MET0.26951599
121MAPKAPK30.24964092
122CSNK1E0.24835111
123FLT30.23331727

Predicted pathways (KEGG)

RankGene SetZ-score
1* Proteasome_Homo sapiens_hsa030505.56082201
2Ribosome_Homo sapiens_hsa030104.20946705
3RNA polymerase_Homo sapiens_hsa030203.77211952
4Oxidative phosphorylation_Homo sapiens_hsa001903.49592452
5DNA replication_Homo sapiens_hsa030303.44072981
6Mismatch repair_Homo sapiens_hsa034303.11223530
7Parkinsons disease_Homo sapiens_hsa050123.05085476
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.00904178
9Protein export_Homo sapiens_hsa030602.73887728
10Spliceosome_Homo sapiens_hsa030402.62421929
11Pyrimidine metabolism_Homo sapiens_hsa002402.42658278
12Nucleotide excision repair_Homo sapiens_hsa034202.38062345
13Homologous recombination_Homo sapiens_hsa034402.37299998
14Huntingtons disease_Homo sapiens_hsa050162.34657097
15RNA transport_Homo sapiens_hsa030132.22672927
16Base excision repair_Homo sapiens_hsa034102.12244411
17Alzheimers disease_Homo sapiens_hsa050102.01023520
18Basal transcription factors_Homo sapiens_hsa030221.97959150
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.83654697
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.76299815
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.69438500
22Non-homologous end-joining_Homo sapiens_hsa034501.61832269
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.56049196
24Cell cycle_Homo sapiens_hsa041101.54727904
25RNA degradation_Homo sapiens_hsa030181.52889488
26Purine metabolism_Homo sapiens_hsa002301.39540656
27Fanconi anemia pathway_Homo sapiens_hsa034601.38924261
28One carbon pool by folate_Homo sapiens_hsa006701.37649299
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.25788669
30Epstein-Barr virus infection_Homo sapiens_hsa051691.12911660
31Propanoate metabolism_Homo sapiens_hsa006401.06498313
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05670356
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.99417279
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.93826589
35Collecting duct acid secretion_Homo sapiens_hsa049660.93467476
36Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92569724
37Pentose and glucuronate interconversions_Homo sapiens_hsa000400.88050924
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87630298
39Selenocompound metabolism_Homo sapiens_hsa004500.87466487
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86577077
41Glutathione metabolism_Homo sapiens_hsa004800.85907452
42Fatty acid elongation_Homo sapiens_hsa000620.82814609
43Steroid biosynthesis_Homo sapiens_hsa001000.81549575
44Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81228449
45Folate biosynthesis_Homo sapiens_hsa007900.79914901
46Vibrio cholerae infection_Homo sapiens_hsa051100.79366848
47Cardiac muscle contraction_Homo sapiens_hsa042600.79054253
48mRNA surveillance pathway_Homo sapiens_hsa030150.78424540
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.73974583
50Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.70414981
51SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69752203
52Allograft rejection_Homo sapiens_hsa053300.69013436
53Graft-versus-host disease_Homo sapiens_hsa053320.66930805
54Rheumatoid arthritis_Homo sapiens_hsa053230.64047809
55p53 signaling pathway_Homo sapiens_hsa041150.63743691
56Legionellosis_Homo sapiens_hsa051340.63555559
57Metabolic pathways_Homo sapiens_hsa011000.62674689
58Pentose phosphate pathway_Homo sapiens_hsa000300.61060377
59Systemic lupus erythematosus_Homo sapiens_hsa053220.59810323
60Galactose metabolism_Homo sapiens_hsa000520.58466676
61Arachidonic acid metabolism_Homo sapiens_hsa005900.55237063
62Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51870345
63Phagosome_Homo sapiens_hsa041450.51680083
64Regulation of autophagy_Homo sapiens_hsa041400.51600950
65Peroxisome_Homo sapiens_hsa041460.51550726
66Oocyte meiosis_Homo sapiens_hsa041140.51308797
67Vitamin B6 metabolism_Homo sapiens_hsa007500.50938377
68Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.47676047
69Type I diabetes mellitus_Homo sapiens_hsa049400.47589498
70Antigen processing and presentation_Homo sapiens_hsa046120.47317924
71Asthma_Homo sapiens_hsa053100.46189766
72Autoimmune thyroid disease_Homo sapiens_hsa053200.43298758
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.42283008
74Herpes simplex infection_Homo sapiens_hsa051680.42174862
75Carbon metabolism_Homo sapiens_hsa012000.41912079
76Chemical carcinogenesis_Homo sapiens_hsa052040.41673738
77Caffeine metabolism_Homo sapiens_hsa002320.37860614
78Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37618771
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37349268
80Ether lipid metabolism_Homo sapiens_hsa005650.36381542
81Fatty acid metabolism_Homo sapiens_hsa012120.36189106
82Biosynthesis of amino acids_Homo sapiens_hsa012300.36150828
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35616859
84Pyruvate metabolism_Homo sapiens_hsa006200.34537322
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.33593588
86Shigellosis_Homo sapiens_hsa051310.33367015
87Viral carcinogenesis_Homo sapiens_hsa052030.32083419
88Fatty acid degradation_Homo sapiens_hsa000710.30107344
89N-Glycan biosynthesis_Homo sapiens_hsa005100.29698934
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28349968
91Butanoate metabolism_Homo sapiens_hsa006500.27357100
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26729438
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26353099
94NOD-like receptor signaling pathway_Homo sapiens_hsa046210.25456572
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.25324517
96Sphingolipid metabolism_Homo sapiens_hsa006000.25041488
97Linoleic acid metabolism_Homo sapiens_hsa005910.24746236
98Arginine and proline metabolism_Homo sapiens_hsa003300.23524365
99Fructose and mannose metabolism_Homo sapiens_hsa000510.23123972
100Arginine biosynthesis_Homo sapiens_hsa002200.22642440
101Tyrosine metabolism_Homo sapiens_hsa003500.21700008
102Vitamin digestion and absorption_Homo sapiens_hsa049770.19985250
103Alcoholism_Homo sapiens_hsa050340.19358372
104Steroid hormone biosynthesis_Homo sapiens_hsa001400.19166320
105Retinol metabolism_Homo sapiens_hsa008300.18849972
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17590406
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16431419
108Sulfur relay system_Homo sapiens_hsa041220.16290995
109Starch and sucrose metabolism_Homo sapiens_hsa005000.15477731
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.15290622
111Tryptophan metabolism_Homo sapiens_hsa003800.14136209
112Thyroid cancer_Homo sapiens_hsa052160.13403399
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.11780383
114Renin-angiotensin system_Homo sapiens_hsa046140.11661654
1152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.09492428
116Hematopoietic cell lineage_Homo sapiens_hsa046400.09210192
117Phenylalanine metabolism_Homo sapiens_hsa003600.09200551
118Pertussis_Homo sapiens_hsa051330.08944827
119Sulfur metabolism_Homo sapiens_hsa009200.08766261
120Apoptosis_Homo sapiens_hsa042100.08586336
121Primary immunodeficiency_Homo sapiens_hsa053400.08490196
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07856376
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.07328385
124RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.06829878
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.06604931
126Phototransduction_Homo sapiens_hsa047440.06531345

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