PSMB8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.80646702
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.80646702
3antigen processing and presentation of endogenous antigen (GO:0019883)6.37807384
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.46795970
5ribosomal small subunit assembly (GO:0000028)5.07618913
6positive regulation of gamma-delta T cell activation (GO:0046645)4.96432030
7negative regulation of cell killing (GO:0031342)4.83105020
8negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.83105020
9positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.60016615
10antigen processing and presentation via MHC class Ib (GO:0002475)4.35635985
11regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.14453927
12DNA deamination (GO:0045006)3.98863425
13regulation of B cell receptor signaling pathway (GO:0050855)3.91369981
14immunoglobulin mediated immune response (GO:0016064)3.87082302
15Arp2/3 complex-mediated actin nucleation (GO:0034314)3.86243696
16response to interferon-beta (GO:0035456)3.86022700
17cellular response to interferon-beta (GO:0035458)3.80893107
18positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.71369854
19* cellular response to type I interferon (GO:0071357)3.69913326
20* type I interferon signaling pathway (GO:0060337)3.69913326
21* response to type I interferon (GO:0034340)3.69543551
22detection of bacterium (GO:0016045)3.69462460
23cytidine deamination (GO:0009972)3.69359488
24cytidine metabolic process (GO:0046087)3.69359488
25cytidine catabolic process (GO:0006216)3.69359488
26viral transcription (GO:0019083)3.63986042
27modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.63459833
28modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.63459833
29positive regulation by organism of defense response of other organism involved in symbiotic interact3.63459833
30modulation by symbiont of host immune response (GO:0052553)3.63459833
31positive regulation by symbiont of host defense response (GO:0052509)3.63459833
32modulation by symbiont of host defense response (GO:0052031)3.63459833
33positive regulation of B cell differentiation (GO:0045579)3.62040197
34regulation of gamma-delta T cell differentiation (GO:0045586)3.59937724
35detection of other organism (GO:0098543)3.59323819
36negative thymic T cell selection (GO:0045060)3.49537109
37NIK/NF-kappaB signaling (GO:0038061)3.48615153
38regulation of T cell tolerance induction (GO:0002664)3.47591740
39mast cell activation (GO:0045576)3.47099255
40translational termination (GO:0006415)3.46661268
41cellular response to zinc ion (GO:0071294)3.45343878
42negative T cell selection (GO:0043383)3.45197832
43macrophage activation involved in immune response (GO:0002281)3.44683055
44leukocyte aggregation (GO:0070486)3.44327960
45regulation of B cell differentiation (GO:0045577)3.42743640
46regulation of gamma-delta T cell activation (GO:0046643)3.38781563
47B cell mediated immunity (GO:0019724)3.36773182
48positive T cell selection (GO:0043368)3.35844213
49negative regulation of phagocytosis (GO:0050765)3.34445457
50defense response to protozoan (GO:0042832)3.34185989
51regulation of tolerance induction (GO:0002643)3.34092043
52regulation of regulatory T cell differentiation (GO:0045589)3.32666512
53T cell migration (GO:0072678)3.32389851
54regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.30253269
55regulation of natural killer cell mediated immunity (GO:0002715)3.30253269
56regulation of interferon-beta biosynthetic process (GO:0045357)3.29969401
57negative regulation of interleukin-12 production (GO:0032695)3.29378357
58pyrimidine ribonucleoside catabolic process (GO:0046133)3.28958718
59positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.23816659
60interferon-gamma-mediated signaling pathway (GO:0060333)3.21517677
61regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.19900089
62myeloid dendritic cell activation (GO:0001773)3.18982512
63B cell receptor signaling pathway (GO:0050853)3.18893654
64regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.18049923
65regulation of T cell receptor signaling pathway (GO:0050856)3.18036468
66SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.15380746
67response to protozoan (GO:0001562)3.14703115
68negative regulation of lymphocyte mediated immunity (GO:0002707)3.13920095
69regulation of leukocyte mediated cytotoxicity (GO:0001910)3.13676634
70response to peptidoglycan (GO:0032494)3.11230523
71regulation of type I interferon-mediated signaling pathway (GO:0060338)3.09931311
72positive regulation of tolerance induction (GO:0002645)3.08807305
73ribosomal small subunit biogenesis (GO:0042274)3.08796073
74positive regulation of antigen processing and presentation (GO:0002579)3.07562523
75cotranslational protein targeting to membrane (GO:0006613)3.06193270
76cellular response to interferon-gamma (GO:0071346)3.05777996
77protein targeting to ER (GO:0045047)3.05278792
78myeloid cell activation involved in immune response (GO:0002275)3.02814573
79translational elongation (GO:0006414)3.01939977
80positive regulation of cell killing (GO:0031343)3.01218428
81regulation of dendritic cell antigen processing and presentation (GO:0002604)3.00602664
82positive regulation of interferon-alpha production (GO:0032727)2.99331097
83T cell homeostasis (GO:0043029)2.99063554
84positive thymic T cell selection (GO:0045059)2.99043364
85negative regulation of leukocyte mediated immunity (GO:0002704)2.98512369
86interferon-gamma production (GO:0032609)2.98002368
87response to interferon-alpha (GO:0035455)2.97914112
88neutrophil activation involved in immune response (GO:0002283)2.97878137
89response to interleukin-15 (GO:0070672)2.97527108
90telomere maintenance via semi-conservative replication (GO:0032201)2.97189204
91regulation of necroptotic process (GO:0060544)2.93782767
92regulation of cell killing (GO:0031341)2.93341945
93protein localization to endoplasmic reticulum (GO:0070972)2.91937145
94neutrophil activation (GO:0042119)2.91079742
95regulation of response to interferon-gamma (GO:0060330)2.90475701
96tolerance induction (GO:0002507)2.89217869
97respiratory burst (GO:0045730)2.88924490
98establishment of protein localization to endoplasmic reticulum (GO:0072599)2.88385012
99regulation of interleukin-12 biosynthetic process (GO:0045075)2.86685291
100sequestering of actin monomers (GO:0042989)2.86459470
101lymphocyte migration (GO:0072676)2.86059203
102T cell receptor signaling pathway (GO:0050852)2.85978660
103regulation of RIG-I signaling pathway (GO:0039535)2.85642478
104response to interferon-gamma (GO:0034341)2.84314101
105regulation of interferon-alpha production (GO:0032647)2.83765502
106myeloid dendritic cell differentiation (GO:0043011)2.82619290
107detection of external biotic stimulus (GO:0098581)2.80942523
108regulation of antigen processing and presentation (GO:0002577)2.80578651
109cellular response to interleukin-15 (GO:0071350)2.80056148
110actin nucleation (GO:0045010)2.80051751
111positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.79187327
112regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.78128667
113negative regulation of innate immune response (GO:0045824)2.77684937
114regulation of alpha-beta T cell proliferation (GO:0046640)2.76395404
115regulation of interleukin-2 biosynthetic process (GO:0045076)2.74966614
116adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.74907361
117positive regulation of natural killer cell mediated immunity (GO:0002717)2.73683314
118viral life cycle (GO:0019058)2.73309545
119positive regulation of macrophage differentiation (GO:0045651)2.72072863
120antigen receptor-mediated signaling pathway (GO:0050851)2.71606482
121DNA strand elongation involved in DNA replication (GO:0006271)2.70999773
122thymic T cell selection (GO:0045061)2.70183726
123cellular response to exogenous dsRNA (GO:0071360)2.67382019
124positive regulation of lamellipodium assembly (GO:0010592)2.66394167
125regulation of T cell mediated cytotoxicity (GO:0001914)2.64998284
126nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.64789059
127telomere maintenance via recombination (GO:0000722)2.64443890
128mature B cell differentiation involved in immune response (GO:0002313)2.61298221
129natural killer cell activation (GO:0030101)2.60240237
130positive regulation of alpha-beta T cell proliferation (GO:0046641)2.60191048
131DNA strand elongation (GO:0022616)2.59654424
132lymph node development (GO:0048535)2.59013640
133maturation of SSU-rRNA (GO:0030490)2.58335377
134cellular protein complex disassembly (GO:0043624)2.56416535
135T cell costimulation (GO:0031295)2.56098562
136necroptotic process (GO:0070266)2.55307742
137mature B cell differentiation (GO:0002335)2.54990711
138lymphocyte homeostasis (GO:0002260)2.54774770
139lymphocyte costimulation (GO:0031294)2.54374240
140negative regulation of viral genome replication (GO:0045071)2.54291553
141positive regulation of T cell mediated cytotoxicity (GO:0001916)2.54031096
142mast cell degranulation (GO:0043303)2.53873084
143mast cell activation involved in immune response (GO:0002279)2.53873084
144T cell selection (GO:0045058)2.51375903

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.23792385
2* IRF8_22096565_ChIP-ChIP_GC-B_Human4.93674891
3* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.01702744
4* IRF8_21731497_ChIP-ChIP_J774_Mouse3.63860192
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.49054175
6* IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.14072269
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.13144965
8* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.03964491
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.00329418
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.79453133
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.68485970
12* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.65823357
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.54796630
14RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.51928264
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.50142299
16SCL_19346495_ChIP-Seq_HPC-7_Human2.46760511
17FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.37838305
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.37758618
19MYC_22102868_ChIP-Seq_BL_Human2.37675935
20MYB_26560356_Chip-Seq_TH2_Human2.26739277
21* SPI1_23547873_ChIP-Seq_NB4_Human2.25639862
22VDR_21846776_ChIP-Seq_THP-1_Human2.25496093
23* IRF8_27001747_Chip-Seq_BMDM_Mouse2.19020628
24EGR1_19374776_ChIP-ChIP_THP-1_Human2.16494758
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.14494748
26TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.13582382
27SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.09526348
28* MAF_26560356_Chip-Seq_TH1_Human2.06682573
29* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.05761424
30MYB_26560356_Chip-Seq_TH1_Human1.95647669
31SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.91565819
32MYC_18555785_ChIP-Seq_MESCs_Mouse1.87943145
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.85853828
34FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.84953494
35* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.83694029
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.83253968
37* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.79686727
38FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.79678922
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.77795893
40VDR_24763502_ChIP-Seq_THP-1_Human1.77679509
41RUNX_20019798_ChIP-Seq_JUKART_Human1.74577178
42UTX_26944678_Chip-Seq_JUKART_Human1.74476364
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.72598517
44MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.68853923
45ERG_20887958_ChIP-Seq_HPC-7_Mouse1.68719162
46GABP_17652178_ChIP-ChIP_JURKAT_Human1.68464084
47VDR_23849224_ChIP-Seq_CD4+_Human1.66998972
48E2F4_17652178_ChIP-ChIP_JURKAT_Human1.65576861
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64085385
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63554786
51GATA1_22025678_ChIP-Seq_K562_Human1.60847204
52EST1_17652178_ChIP-ChIP_JURKAT_Human1.55605910
53LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.48464885
54FOXP3_21729870_ChIP-Seq_TREG_Human1.46971949
55LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.46140851
56GATA2_22383799_ChIP-Seq_G1ME_Mouse1.44841922
57MAF_26560356_Chip-Seq_TH2_Human1.44676759
58MYC_18358816_ChIP-ChIP_MESCs_Mouse1.42757376
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42417970
60E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.41185481
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.40401166
62RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.34909027
63CIITA_25753668_ChIP-Seq_RAJI_Human1.33489972
64* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.32620948
65ETS1_20019798_ChIP-Seq_JURKAT_Human1.30960589
66BCL6_27268052_Chip-Seq_Bcells_Human1.30728157
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.30456876
68KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.28552417
69* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28376832
70GATA3_27048872_Chip-Seq_THYMUS_Human1.25936298
71SPI1_23127762_ChIP-Seq_K562_Human1.23242278
72TCF7_22412390_ChIP-Seq_EML_Mouse1.22586964
73GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.21469647
74EGR1_23403033_ChIP-Seq_LIVER_Mouse1.21012305
75XRN2_22483619_ChIP-Seq_HELA_Human1.19737526
76CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.17169939
77SMAD_19615063_ChIP-ChIP_OVARY_Human1.16854674
78MYC_19030024_ChIP-ChIP_MESCs_Mouse1.16220350
79VDR_24787735_ChIP-Seq_THP-1_Human1.16002581
80HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14971156
81GATA1_19941827_ChIP-Seq_MEL_Mouse1.11020220
82* PU_27001747_Chip-Seq_BMDM_Mouse1.10771778
83SRF_21415370_ChIP-Seq_HL-1_Mouse1.10046601
84CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09797365
85PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09663650
86BCOR_27268052_Chip-Seq_Bcells_Human1.08848499
87MYC_19079543_ChIP-ChIP_MESCs_Mouse1.08520244
88Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.08324289
89PU.1_20513432_ChIP-Seq_Bcells_Mouse1.07276493
90CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.07113365
91FOXM1_23109430_ChIP-Seq_U2OS_Human1.06573822
92VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.06065969
93ELK1_19687146_ChIP-ChIP_HELA_Human1.03340716
94DCP1A_22483619_ChIP-Seq_HELA_Human1.02984051
95VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01086949
96E2F1_21310950_ChIP-Seq_MCF-7_Human1.01083786
97CREB1_15753290_ChIP-ChIP_HEK293T_Human1.00373356
98GATA3_26560356_Chip-Seq_TH2_Human0.99823570
99* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.99510329
100ELF1_20517297_ChIP-Seq_JURKAT_Human0.98781456
101STAT1_20625510_ChIP-Seq_HELA_Human0.98285097
102GABP_19822575_ChIP-Seq_HepG2_Human0.96940458
103P300_27268052_Chip-Seq_Bcells_Human0.96537100
104NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.94849794
105LXR_22292898_ChIP-Seq_THP-1_Human0.94226175
106TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94178480
107CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.94066053
108CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93953364
109ELK3_25401928_ChIP-Seq_HUVEC_Human0.93767982
110IKZF1_21737484_ChIP-ChIP_HCT116_Human0.93232712
111PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93129594
112* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.93093075
113E2F1_18555785_ChIP-Seq_MESCs_Mouse0.92520632
114TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91766756
115CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91502262
116SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90270526
117NELFA_20434984_ChIP-Seq_ESCs_Mouse0.89404234
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87383817
119FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86021793
120GATA1_19941826_ChIP-Seq_K562_Human0.85749198
121SPI1_20517297_ChIP-Seq_HL60_Human0.84430130
122KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.81745590
123RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81318149
124KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80693135
125PPARA_22158963_ChIP-Seq_LIVER_Mouse0.80472418
126CTCF_26484167_Chip-Seq_Bcells_Mouse0.79931610
127KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.76440005
128BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.76308076
129KDM2B_26808549_Chip-Seq_DND41_Human0.75666530

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0001835_abnormal_antigen_presentation4.62501237
2MP0005671_abnormal_response_to3.77442294
3MP0000685_abnormal_immune_system3.56717664
4MP0009785_altered_susceptibility_to3.47488364
5MP0003763_abnormal_thymus_physiology3.21303488
6MP0001800_abnormal_humoral_immune3.03591696
7MP0005025_abnormal_response_to2.91444705
8MP0005000_abnormal_immune_tolerance2.87470089
9MP0005387_immune_system_phenotype2.85828904
10MP0001790_abnormal_immune_system2.85828904
11MP0002396_abnormal_hematopoietic_system2.82361702
12MP0003436_decreased_susceptibility_to2.76391893
13MP0002452_abnormal_antigen_presenting2.74037017
14MP0002723_abnormal_immune_serum2.71998684
15MP0002148_abnormal_hypersensitivity_rea2.71645813
16MP0002420_abnormal_adaptive_immunity2.68346977
17MP0001819_abnormal_immune_cell2.66916260
18MP0003724_increased_susceptibility_to2.56863261
19MP0002398_abnormal_bone_marrow2.51314714
20MP0002419_abnormal_innate_immunity2.44715755
21* MP0002166_altered_tumor_susceptibility2.33912927
22* MP0000716_abnormal_immune_system2.26658526
23MP0009333_abnormal_splenocyte_physiolog2.17417513
24MP0001853_heart_inflammation2.13873082
25MP0005464_abnormal_platelet_physiology2.13136689
26MP0002405_respiratory_system_inflammati2.07230717
27MP0000689_abnormal_spleen_morphology2.07209751
28MP0010155_abnormal_intestine_physiology2.05146387
29MP0006082_CNS_inflammation2.03762386
30MP0002722_abnormal_immune_system2.02438386
31* MP0002006_tumorigenesis2.00276222
32* MP0002429_abnormal_blood_cell1.94980793
33MP0001873_stomach_inflammation1.93159820
34MP0001845_abnormal_inflammatory_respons1.78319091
35MP0005397_hematopoietic_system_phenotyp1.76450028
36MP0001545_abnormal_hematopoietic_system1.76450028
37MP0004808_abnormal_hematopoietic_stem1.72372834
38MP0004947_skin_inflammation1.69440127
39MP0004510_myositis1.68290539
40MP0000703_abnormal_thymus_morphology1.68224975
41MP0003866_abnormal_defecation1.62895862
42MP0000490_abnormal_crypts_of1.59379110
43MP0003303_peritoneal_inflammation1.58572778
44MP0005174_abnormal_tail_pigmentation1.56854618
45MP0005075_abnormal_melanosome_morpholog1.53022844
46MP0008469_abnormal_protein_level1.51769139
47MP0000465_gastrointestinal_hemorrhage1.48117610
48MP0008057_abnormal_DNA_replication1.44198806
49MP0003693_abnormal_embryo_hatching1.38485009
50MP0003806_abnormal_nucleotide_metabolis1.37947911
51MP0000858_altered_metastatic_potential1.36919200
52MP0005310_abnormal_salivary_gland1.36492608
53MP0002933_joint_inflammation1.29631637
54MP0005360_urolithiasis1.28085411
55MP0001533_abnormal_skeleton_physiology1.27380888
56MP0003300_gastrointestinal_ulcer1.27317433
57MP0010094_abnormal_chromosome_stability1.19065157
58MP0002019_abnormal_tumor_incidence1.18689365
59MP0009764_decreased_sensitivity_to1.12038940
60MP0003448_altered_tumor_morphology1.07850335
61MP0002095_abnormal_skin_pigmentation1.06433821
62MP0003077_abnormal_cell_cycle1.04273717
63MP0003191_abnormal_cellular_cholesterol1.02302902
64MP0008007_abnormal_cellular_replicative1.00315143
65MP0000343_altered_response_to0.95454274
66MP0005058_abnormal_lysosome_morphology0.95445460
67MP0002132_abnormal_respiratory_system0.94996922
68MP0009278_abnormal_bone_marrow0.94978210
69MP0002277_abnormal_respiratory_mucosa0.94513589
70MP0010352_gastrointestinal_tract_polyps0.92839740
71MP0008058_abnormal_DNA_repair0.91255569
72MP0005451_abnormal_body_composition0.90560460
73MP0003172_abnormal_lysosome_physiology0.90071426
74MP0003186_abnormal_redox_activity0.88132696
75MP0009763_increased_sensitivity_to0.87776525
76MP0003045_fibrosis0.87234725
77MP0000015_abnormal_ear_pigmentation0.86512028
78MP0004957_abnormal_blastocyst_morpholog0.81127744
79MP0002139_abnormal_hepatobiliary_system0.78431151
80MP0010307_abnormal_tumor_latency0.76877952
81MP0003252_abnormal_bile_duct0.75253097
82MP0002138_abnormal_hepatobiliary_system0.75159072
83MP0001851_eye_inflammation0.71447832
84MP0004381_abnormal_hair_follicle0.71315425
85MP0000313_abnormal_cell_death0.70741181
86MP0005165_increased_susceptibility_to0.70085963
87MP0003111_abnormal_nucleus_morphology0.69335598
88MP0002998_abnormal_bone_remodeling0.68667345
89MP0005390_skeleton_phenotype0.68576444
90MP0008260_abnormal_autophagy0.67470452
91MP0001663_abnormal_digestive_system0.67120132
92MP0009379_abnormal_foot_pigmentation0.66077625
93MP0000604_amyloidosis0.65704873
94MP0008004_abnormal_stomach_pH0.64759837
95MP0001348_abnormal_lacrimal_gland0.64601448
96MP0003795_abnormal_bone_structure0.64546482
97MP0004883_abnormal_blood_vessel0.64510825
98MP0006054_spinal_hemorrhage0.64481142
99MP0000371_diluted_coat_color0.63305637
100MP0009643_abnormal_urine_homeostasis0.62765256
101MP0005164_abnormal_response_to0.62503156
102MP0009840_abnormal_foam_cell0.62271992
103MP0002693_abnormal_pancreas_physiology0.61332337
104MP0004782_abnormal_surfactant_physiolog0.60405220
105MP0003943_abnormal_hepatobiliary_system0.58990654
106MP0000609_abnormal_liver_physiology0.57548889
107MP0000477_abnormal_intestine_morphology0.57428805
108MP0000249_abnormal_blood_vessel0.56979756
109MP0009765_abnormal_xenobiotic_induced0.55971563
110MP0005319_abnormal_enzyme/_coenzyme0.55914936
111MP0003075_altered_response_to0.55117118
112MP0005166_decreased_susceptibility_to0.54907275
113MP0000598_abnormal_liver_morphology0.54588244
114MP0008875_abnormal_xenobiotic_pharmacok0.54295821
115MP0003183_abnormal_peptide_metabolism0.53974994
116MP0003828_pulmonary_edema0.53206416
117MP0008873_increased_physiological_sensi0.52967165
118MP0005381_digestive/alimentary_phenotyp0.52876158
119MP0002136_abnormal_kidney_physiology0.52822068
120MP0003656_abnormal_erythrocyte_physiolo0.52748447
121MP0005377_hearing/vestibular/ear_phenot0.52571918
122MP0003878_abnormal_ear_physiology0.52571918
123MP0005584_abnormal_enzyme/coenzyme_acti0.51781910
124MP0002009_preneoplasia0.51226212
125MP0005085_abnormal_gallbladder_physiolo0.49296308

Predicted human phenotypes

RankGene SetZ-score
1Chronic otitis media (HP:0000389)5.38401993
2Recurrent bronchitis (HP:0002837)4.74140669
3Recurrent abscess formation (HP:0002722)4.61135139
4IgM deficiency (HP:0002850)4.59699480
5Myositis (HP:0100614)4.46340860
6Eczematoid dermatitis (HP:0000976)4.38577053
7Thrombocytosis (HP:0001894)4.28535616
8Recurrent bacterial skin infections (HP:0005406)4.10528070
9* Elevated erythrocyte sedimentation rate (HP:0003565)4.03121822
10Recurrent viral infections (HP:0004429)3.99654877
11Recurrent fungal infections (HP:0002841)3.99254937
12Chronic mucocutaneous candidiasis (HP:0002728)3.69329899
13Recurrent cutaneous fungal infections (HP:0011370)3.69329899
14Nasal polyposis (HP:0100582)3.68175422
15Abnormality of T cells (HP:0002843)3.67387400
16Abnormality of T cell physiology (HP:0011840)3.63158795
17Panhypogammaglobulinemia (HP:0003139)3.55736355
18IgG deficiency (HP:0004315)3.54819380
19Agammaglobulinemia (HP:0004432)3.44340640
20Abnormality of T cell number (HP:0011839)3.43408194
21Abnormality of the nasal mucosa (HP:0000433)3.42076664
22Recurrent skin infections (HP:0001581)3.39707841
23T lymphocytopenia (HP:0005403)3.39287701
24Meningitis (HP:0001287)3.37058932
25Abnormal delayed hypersensitivity skin test (HP:0002963)3.31597051
26Petechiae (HP:0000967)3.26873048
27Severe combined immunodeficiency (HP:0004430)3.25703968
28Vasculitis (HP:0002633)3.18441503
29Abnormality of B cell number (HP:0010975)3.17514920
30B lymphocytopenia (HP:0010976)3.17514920
31Mediastinal lymphadenopathy (HP:0100721)3.14688853
32Thyroiditis (HP:0100646)3.12647460
33Lymphopenia (HP:0001888)3.12167430
34Abnormality of cells of the lymphoid lineage (HP:0012140)3.09683780
35Combined immunodeficiency (HP:0005387)3.06959608
36Abnormality of cells of the erythroid lineage (HP:0012130)3.05988556
37Abnormal number of erythroid precursors (HP:0012131)3.05522365
38Autoimmune thrombocytopenia (HP:0001973)3.05409780
39Chronic sinusitis (HP:0011109)2.97446020
40Reticulocytopenia (HP:0001896)2.95057382
41Orchitis (HP:0100796)2.91725134
42Increased IgM level (HP:0003496)2.90251473
43Cellulitis (HP:0100658)2.86603097
44Autoimmune hemolytic anemia (HP:0001890)2.83096952
45Obstructive lung disease (HP:0006536)2.81253906
46Chronic obstructive pulmonary disease (HP:0006510)2.81253906
47Pustule (HP:0200039)2.80022963
48Abnormality of macrophages (HP:0004311)2.80022562
49Retrobulbar optic neuritis (HP:0100654)2.78032253
50Optic neuritis (HP:0100653)2.78032253
51Recurrent gram-negative bacterial infections (HP:0005420)2.76989914
52Inflammation of the large intestine (HP:0002037)2.75481315
53Gastrointestinal inflammation (HP:0004386)2.74957873
54Interstitial pulmonary disease (HP:0006530)2.72522884
55Chronic diarrhea (HP:0002028)2.69157500
56Stomatitis (HP:0010280)2.69010682
57Bronchitis (HP:0012387)2.67765059
58Aplastic anemia (HP:0001915)2.67564891
59Keratoconjunctivitis (HP:0001096)2.67279127
60Spontaneous hematomas (HP:0007420)2.66477093
61Gastrointestinal stroma tumor (HP:0100723)2.64029213
62Recurrent sinusitis (HP:0011108)2.62549800
63Hypoplasia of the thymus (HP:0000778)2.62395326
64Abnormality of eosinophils (HP:0001879)2.60467779
65Lymphoma (HP:0002665)2.60182494
66IgA deficiency (HP:0002720)2.59894817
67Leukocytosis (HP:0001974)2.59245500
68Granulocytopenia (HP:0001913)2.56310447
69Eosinophilia (HP:0001880)2.53899984
70Prolonged bleeding time (HP:0003010)2.53752258
71Systemic lupus erythematosus (HP:0002725)2.51973052
72Hemoptysis (HP:0002105)2.50218218
73Abnormality of the pleura (HP:0002103)2.47429182
74Colitis (HP:0002583)2.47393283
75Epistaxis (HP:0000421)2.46180645
76Encephalitis (HP:0002383)2.45984398
77Abnormality of the prostate (HP:0008775)2.44194466
78Joint swelling (HP:0001386)2.43797235
79Gangrene (HP:0100758)2.40965505
80Reduced antithrombin III activity (HP:0001976)2.35316557
81* Hypergammaglobulinemia (HP:0010702)2.31676568
82Acute hepatic failure (HP:0006554)2.30278808
83Pulmonary infiltrates (HP:0002113)2.29962572
84Vacuolated lymphocytes (HP:0001922)2.29223001
85Pulmonary embolism (HP:0002204)2.28690856
86Increased IgE level (HP:0003212)2.28539628
87Hypoproteinemia (HP:0003075)2.28178792
88Poikiloderma (HP:0001029)2.27680469
89Increased serum ferritin (HP:0003281)2.27151949
90Anorexia (HP:0002039)2.26469074
91* Skin rash (HP:0000988)2.25143443
92Pallor (HP:0000980)2.24153952
93Recurrent pneumonia (HP:0006532)2.21476660
94Gingival bleeding (HP:0000225)2.18866805
95Recurrent lower respiratory tract infections (HP:0002783)2.18852842
96Periodontitis (HP:0000704)2.17929951
97Osteomyelitis (HP:0002754)2.14651505
98Emphysema (HP:0002097)2.14005398
99Skin ulcer (HP:0200042)2.12641950
100Gingivitis (HP:0000230)2.11288316
101Hepatosplenomegaly (HP:0001433)2.10774008
102Arterial thrombosis (HP:0004420)2.10770654
103Purpura (HP:0000979)2.08659444
104Neutropenia (HP:0001875)2.08000338
105Keratoconjunctivitis sicca (HP:0001097)2.07932195
106Abnormal platelet function (HP:0011869)2.06780103
107Impaired platelet aggregation (HP:0003540)2.06780103
108Verrucae (HP:0200043)2.05926275
109Papilloma (HP:0012740)2.05926275
110Type I transferrin isoform profile (HP:0003642)2.03305862
111Abnormality of iron homeostasis (HP:0011031)2.02344906
112Urticaria (HP:0001025)2.01306076
113Restrictive lung disease (HP:0002091)2.00109469
114* Arthralgia (HP:0002829)1.97824929
115Gastrointestinal infarctions (HP:0005244)1.95848314
116Chest pain (HP:0100749)1.95812557
117Sepsis (HP:0100806)1.94035889

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.69127603
2KIT3.11095097
3TXK3.00484088
4TBK12.78710584
5TYK22.78660060
6BLK2.77902697
7IKBKE2.77368186
8NME22.62015480
9JAK32.59800088
10ZAP702.40244304
11MAP3K142.34729833
12TEC2.25834481
13IRAK42.25201444
14BTK2.16827059
15KDR2.08767298
16SYK1.89003407
17GRK71.88443921
18CSF1R1.84060320
19FGFR41.79555415
20FLT31.70200616
21STK161.68715502
22PIM21.67740603
23BMPR21.67520074
24IKBKB1.57715459
25JAK11.47036639
26TESK21.46028830
27LCK1.42590622
28ITK1.40293372
29MAP3K121.37288889
30NLK1.33579979
31ERN11.32677258
32PRPF4B1.29934410
33EEF2K1.25599246
34LYN1.24934951
35MAP2K31.20846815
36ACVR1B1.20184276
37STK101.18975237
38GRK61.18751865
39MOS1.17696855
40TGFBR11.16574082
41FES1.16098143
42LRRK21.16043884
43FGFR31.15196973
44RPS6KA41.10894793
45HCK1.04904332
46CLK11.04301536
47TAOK31.04131395
48MARK31.02276047
49PIM11.01044024
50IRAK30.98304214
51RIPK40.98145295
52CSK0.98097999
53MST40.97282289
54MAP3K30.95463333
55TGFBR20.94362637
56VRK20.94059689
57EIF2AK30.93749901
58VRK10.90870219
59SCYL20.90711276
60GRK50.89801738
61MAP3K130.89139644
62TAOK20.85860879
63BCKDK0.83999124
64PKN20.80251218
65SMG10.78595837
66CHUK0.78260745
67FGR0.78208597
68EIF2AK10.75729403
69WEE10.74739822
70CDC70.73771034
71PDK10.71947025
72MAP3K110.69620769
73RPS6KB20.69345781
74BUB10.68999410
75MAP3K100.68709376
76MATK0.68212537
77MAPK110.67152462
78CDK190.65771798
79STK40.63998540
80JAK20.63961931
81TESK10.62632808
82CDK40.61558504
83NEK90.61531939
84PIK3CG0.60019800
85MAP3K10.59452491
86ADRBK20.59108889
87TLK10.58623216
88TNK20.56722701
89ATR0.55930114
90HIPK20.55516065
91TAOK10.55492918
92MAP2K60.54033848
93NEK20.49401287
94EPHA30.48260051
95EIF2AK20.48164062
96FYN0.47905611
97PASK0.46106169
98RPS6KA60.43588909
99PRKCQ0.43583427
100MAP3K50.43362702
101MAPKAPK30.43114588
102TNIK0.41028844
103DAPK10.40120711
104SIK30.40002769
105PRKCD0.39259138
106MYLK0.38441261
107DYRK30.38355249
108MAPK40.38053040
109ILK0.37986621
110MAPK120.37919967
111BRSK20.37645590
112CDK70.36602375
113NUAK10.36597267
114ARAF0.35166820
115AURKB0.33644053
116PAK10.32847610
117EPHB10.32050342
118ABL10.31991506
119CDK80.31777161
120MAPKAPK20.31542980
121IRAK10.31464573
122CCNB10.30714395
123RPS6KA50.30584132
124MAP3K80.30320737
125TIE10.29584199
126CAMKK20.29033756
127IGF1R0.27477621
128PDPK10.27141637
129INSR0.26903735
130PTK60.24205872
131ZAK0.24168510
132DAPK30.22876317

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.10997821
2DNA replication_Homo sapiens_hsa030303.26239593
3Ribosome_Homo sapiens_hsa030103.02889211
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.81581116
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.53993825
6Antigen processing and presentation_Homo sapiens_hsa046122.43934535
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.38225956
8Leishmaniasis_Homo sapiens_hsa051402.34023936
9Measles_Homo sapiens_hsa051622.33536237
10Mismatch repair_Homo sapiens_hsa034302.30372066
11Allograft rejection_Homo sapiens_hsa053302.16153264
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.10868246
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.10212703
14Base excision repair_Homo sapiens_hsa034102.08298024
15Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.95668717
16Herpes simplex infection_Homo sapiens_hsa051681.88830291
17Hematopoietic cell lineage_Homo sapiens_hsa046401.85001410
18B cell receptor signaling pathway_Homo sapiens_hsa046621.84904671
19Graft-versus-host disease_Homo sapiens_hsa053321.80922887
20* Proteasome_Homo sapiens_hsa030501.70396455
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.69399782
22Homologous recombination_Homo sapiens_hsa034401.64279684
23Osteoclast differentiation_Homo sapiens_hsa043801.62474521
24Legionellosis_Homo sapiens_hsa051341.53291263
25T cell receptor signaling pathway_Homo sapiens_hsa046601.52356880
26Jak-STAT signaling pathway_Homo sapiens_hsa046301.43484235
27Nucleotide excision repair_Homo sapiens_hsa034201.41223844
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.37488534
29Influenza A_Homo sapiens_hsa051641.37432435
30Pertussis_Homo sapiens_hsa051331.34961581
31Asthma_Homo sapiens_hsa053101.32573032
32Spliceosome_Homo sapiens_hsa030401.30355853
33Pyrimidine metabolism_Homo sapiens_hsa002401.28307659
34Shigellosis_Homo sapiens_hsa051311.26665282
35Non-homologous end-joining_Homo sapiens_hsa034501.25885990
36Viral myocarditis_Homo sapiens_hsa054161.19534776
37Toxoplasmosis_Homo sapiens_hsa051451.18133440
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.15987935
39Other glycan degradation_Homo sapiens_hsa005111.15288654
40Staphylococcus aureus infection_Homo sapiens_hsa051501.13468367
41Autoimmune thyroid disease_Homo sapiens_hsa053201.13274863
42Apoptosis_Homo sapiens_hsa042101.13115062
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.12283265
44Malaria_Homo sapiens_hsa051441.10924389
45Hepatitis B_Homo sapiens_hsa051611.10384671
46Tuberculosis_Homo sapiens_hsa051521.04807794
47Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03990028
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.01039240
49TNF signaling pathway_Homo sapiens_hsa046681.00322961
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.94512761
51Acute myeloid leukemia_Homo sapiens_hsa052210.92975963
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91542858
53Protein export_Homo sapiens_hsa030600.91278575
54RNA polymerase_Homo sapiens_hsa030200.89812626
55Salmonella infection_Homo sapiens_hsa051320.88603912
56Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88540720
57Chemokine signaling pathway_Homo sapiens_hsa040620.88310070
58Epstein-Barr virus infection_Homo sapiens_hsa051690.88234043
59Pentose phosphate pathway_Homo sapiens_hsa000300.86947084
60Type I diabetes mellitus_Homo sapiens_hsa049400.85324529
61p53 signaling pathway_Homo sapiens_hsa041150.84189635
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83170576
63Leukocyte transendothelial migration_Homo sapiens_hsa046700.82588394
64One carbon pool by folate_Homo sapiens_hsa006700.82341343
65Caffeine metabolism_Homo sapiens_hsa002320.82278999
66Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76093508
67RNA degradation_Homo sapiens_hsa030180.73463388
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72131016
69Hepatitis C_Homo sapiens_hsa051600.69872379
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.67952491
71Platelet activation_Homo sapiens_hsa046110.67728545
72Cell cycle_Homo sapiens_hsa041100.66916870
73HTLV-I infection_Homo sapiens_hsa051660.66603262
74Fanconi anemia pathway_Homo sapiens_hsa034600.66330319
75Viral carcinogenesis_Homo sapiens_hsa052030.65898657
76Sulfur relay system_Homo sapiens_hsa041220.65291777
77N-Glycan biosynthesis_Homo sapiens_hsa005100.61882928
78African trypanosomiasis_Homo sapiens_hsa051430.58851624
79Folate biosynthesis_Homo sapiens_hsa007900.55445504
80Systemic lupus erythematosus_Homo sapiens_hsa053220.55349059
81Pancreatic cancer_Homo sapiens_hsa052120.50835302
82Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49154714
83Lysosome_Homo sapiens_hsa041420.48253960
84Rheumatoid arthritis_Homo sapiens_hsa053230.45879076
85Purine metabolism_Homo sapiens_hsa002300.45059096
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44905720
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44664303
88RNA transport_Homo sapiens_hsa030130.44581116
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44297914
90Chronic myeloid leukemia_Homo sapiens_hsa052200.44100973
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42793201
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.42505415
93Arachidonic acid metabolism_Homo sapiens_hsa005900.40180821
94AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.39375804
95Small cell lung cancer_Homo sapiens_hsa052220.38931531
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38698841
97Sulfur metabolism_Homo sapiens_hsa009200.37576108
98SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36454570
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35454836
100Prolactin signaling pathway_Homo sapiens_hsa049170.33198307
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30044060
102alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27740564
103Thyroid cancer_Homo sapiens_hsa052160.27235805
104Endocytosis_Homo sapiens_hsa041440.26437549
105Linoleic acid metabolism_Homo sapiens_hsa005910.26333726
106Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.25885155
107Phagosome_Homo sapiens_hsa041450.24109435
108Alcoholism_Homo sapiens_hsa050340.23794874
109ABC transporters_Homo sapiens_hsa020100.22502501
110Complement and coagulation cascades_Homo sapiens_hsa046100.20803570
111Chemical carcinogenesis_Homo sapiens_hsa052040.17871541
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.16679401
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.16111523
114Renin-angiotensin system_Homo sapiens_hsa046140.15578358
115Galactose metabolism_Homo sapiens_hsa000520.15192013
116Fructose and mannose metabolism_Homo sapiens_hsa000510.13843499
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.11289005
118Non-small cell lung cancer_Homo sapiens_hsa052230.11113129
119Mineral absorption_Homo sapiens_hsa049780.11066957
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09796222
121Regulation of autophagy_Homo sapiens_hsa041400.09444032
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.09111450
123Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09061528
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.08750681
125Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.08255162
126VEGF signaling pathway_Homo sapiens_hsa043700.07112877
127Cyanoamino acid metabolism_Homo sapiens_hsa004600.05885609
128Glycerolipid metabolism_Homo sapiens_hsa005610.05308624
129Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.04426611
130Peroxisome_Homo sapiens_hsa041460.03694239

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