

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 9.47220084 |
| 2 | DNA deamination (GO:0045006) | 9.21089707 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 8.54566401 |
| 4 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.88955204 |
| 5 | negative regulation by host of viral transcription (GO:0043922) | 4.86593139 |
| 6 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.76932482 |
| 7 | eosinophil chemotaxis (GO:0048245) | 4.76257124 |
| 8 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.48996200 |
| 9 | sequestering of actin monomers (GO:0042989) | 4.47243604 |
| 10 | protein neddylation (GO:0045116) | 4.34749088 |
| 11 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.29032899 |
| 12 | eosinophil migration (GO:0072677) | 4.28690009 |
| 13 | actin nucleation (GO:0045010) | 4.19039681 |
| 14 | positive T cell selection (GO:0043368) | 4.12043007 |
| 15 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.11868952 |
| 16 | positive thymic T cell selection (GO:0045059) | 4.11570798 |
| 17 | T cell migration (GO:0072678) | 4.08505377 |
| 18 | cytolysis (GO:0019835) | 4.07172784 |
| 19 | iron-sulfur cluster assembly (GO:0016226) | 4.00858286 |
| 20 | metallo-sulfur cluster assembly (GO:0031163) | 4.00858286 |
| 21 | negative regulation of T cell apoptotic process (GO:0070233) | 3.96630906 |
| 22 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.94145113 |
| 23 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.90214212 |
| 24 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.89688959 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.81938600 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.80638194 |
| 27 | proteasome assembly (GO:0043248) | 3.75452450 |
| 28 | negative regulation of viral genome replication (GO:0045071) | 3.72635634 |
| 29 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.71795509 |
| 30 | macrophage chemotaxis (GO:0048246) | 3.70485318 |
| 31 | positive regulation of T cell chemotaxis (GO:0010820) | 3.67041166 |
| 32 | regulation of T cell chemotaxis (GO:0010819) | 3.67041166 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.65767858 |
| 34 | DNA demethylation (GO:0080111) | 3.60771822 |
| 35 | negative regulation of ligase activity (GO:0051352) | 3.59720937 |
| 36 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.59720937 |
| 37 | regulation of regulatory T cell differentiation (GO:0045589) | 3.59327425 |
| 38 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.58627665 |
| 39 | ATP synthesis coupled proton transport (GO:0015986) | 3.58627665 |
| 40 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55516313 |
| 41 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.55414840 |
| 42 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.55414840 |
| 43 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.55414840 |
| 44 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.54628130 |
| 45 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.54628130 |
| 46 | regulation of interleukin-8 secretion (GO:2000482) | 3.50189363 |
| 47 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.45881453 |
| 48 | respiratory electron transport chain (GO:0022904) | 3.45828023 |
| 49 | NIK/NF-kappaB signaling (GO:0038061) | 3.41840121 |
| 50 | electron transport chain (GO:0022900) | 3.40665453 |
| 51 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.38851661 |
| 52 | lymphocyte chemotaxis (GO:0048247) | 3.37999700 |
| 53 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.37697298 |
| 54 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.37697298 |
| 55 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.36842413 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.35166477 |
| 57 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.34425454 |
| 58 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.33830439 |
| 59 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.29322382 |
| 60 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.29322382 |
| 61 | positive regulation of tolerance induction (GO:0002645) | 3.26320502 |
| 62 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.17326261 |
| 63 | positive regulation of lymphocyte migration (GO:2000403) | 3.17214186 |
| 64 | chaperone-mediated protein transport (GO:0072321) | 3.16680960 |
| 65 | regulation of T cell tolerance induction (GO:0002664) | 3.13555172 |
| 66 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.13482827 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.13482827 |
| 68 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.11302406 |
| 69 | negative regulation of viral transcription (GO:0032897) | 3.11187654 |
| 70 | DNA dealkylation (GO:0035510) | 3.09496564 |
| 71 | monocyte chemotaxis (GO:0002548) | 3.04597862 |
| 72 | platelet dense granule organization (GO:0060155) | 3.03246185 |
| 73 | piRNA metabolic process (GO:0034587) | 3.01264589 |
| 74 | male meiosis I (GO:0007141) | 3.00307280 |
| 75 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.99225437 |
| 76 | positive regulation of cell killing (GO:0031343) | 2.96693165 |
| 77 | positive regulation of translational initiation (GO:0045948) | 2.96108133 |
| 78 | regulation of chronic inflammatory response (GO:0002676) | 2.94663569 |
| 79 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.91032395 |
| 80 | nucleoside diphosphate catabolic process (GO:0009134) | 2.89631674 |
| 81 | protein complex biogenesis (GO:0070271) | 2.88988386 |
| 82 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.88704968 |
| 83 | termination of RNA polymerase III transcription (GO:0006386) | 2.88704968 |
| 84 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.86222356 |
| 85 | regulation of cellular amine metabolic process (GO:0033238) | 2.86062533 |
| 86 | negative T cell selection (GO:0043383) | 2.85825897 |
| 87 | regulation of activation of Janus kinase activity (GO:0010533) | 2.83584989 |
| 88 | positive regulation of ligase activity (GO:0051351) | 2.83302437 |
| 89 | modulation by host of viral transcription (GO:0043921) | 2.81979439 |
| 90 | modulation by host of symbiont transcription (GO:0052472) | 2.81979439 |
| 91 | positive regulation of cell cycle arrest (GO:0071158) | 2.81024314 |
| 92 | positive regulation of T cell apoptotic process (GO:0070234) | 2.79481281 |
| 93 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.78669062 |
| 94 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.75853735 |
| 95 | regulation of calcium-mediated signaling (GO:0050848) | 2.74304846 |
| 96 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.71446590 |
| 97 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.71410334 |
| 98 | cytidine metabolic process (GO:0046087) | 10.5215224 |
| 99 | cytidine catabolic process (GO:0006216) | 10.5215224 |
| 100 | cytidine deamination (GO:0009972) | 10.5215224 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.11952841 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.55244840 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.37129381 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.27333777 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.80908837 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.54937823 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.52592426 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90717290 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.69519920 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.65449143 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.61127349 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.31272641 |
| 13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.22756527 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.14104798 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.13354443 |
| 16 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.07136641 |
| 17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.01903562 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.97536170 |
| 19 | VDR_22108803_ChIP-Seq_LS180_Human | 1.94057507 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93866352 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.90792363 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.78364948 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.73503760 |
| 24 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.68134752 |
| 25 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67805524 |
| 26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.66278914 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.65944869 |
| 28 | MYB_26560356_Chip-Seq_TH2_Human | 1.60803924 |
| 29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.60735829 |
| 30 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.56560481 |
| 31 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.54406237 |
| 32 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.53982736 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.50858875 |
| 34 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.48008233 |
| 35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.47744090 |
| 36 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46248670 |
| 37 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.43331033 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.39137538 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.38116955 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.35122145 |
| 41 | GATA3_26560356_Chip-Seq_TH2_Human | 1.35087210 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34071109 |
| 43 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33764678 |
| 44 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.33017193 |
| 45 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32890746 |
| 46 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.29165131 |
| 47 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.26114576 |
| 48 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.24755420 |
| 49 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.19900758 |
| 50 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19662187 |
| 51 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.18192367 |
| 52 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.17609823 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.16260310 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.16260310 |
| 55 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.16225105 |
| 56 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.15940691 |
| 57 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.15019818 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.14896488 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12501260 |
| 60 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.11816928 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.11807849 |
| 62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11804230 |
| 63 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.11698726 |
| 64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.10910971 |
| 65 | ERA_21632823_ChIP-Seq_H3396_Human | 1.10575361 |
| 66 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09314705 |
| 67 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.08855861 |
| 68 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08483198 |
| 69 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.06682186 |
| 70 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06648668 |
| 71 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.06617603 |
| 72 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05700732 |
| 73 | P300_27268052_Chip-Seq_Bcells_Human | 1.02149189 |
| 74 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.01943767 |
| 75 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.01424458 |
| 76 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.01121779 |
| 77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.00874391 |
| 78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.00874391 |
| 79 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.99792631 |
| 80 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.99768527 |
| 81 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.98910168 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98209375 |
| 83 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.97747311 |
| 84 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.97439982 |
| 85 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.96883449 |
| 86 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.94705453 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93889371 |
| 88 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93774717 |
| 89 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.93735879 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.93379207 |
| 91 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.92968685 |
| 92 | UTX_26944678_Chip-Seq_JUKART_Human | 0.92950253 |
| 93 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.92738376 |
| 94 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92715569 |
| 95 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92288881 |
| 96 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.91738517 |
| 97 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.91345776 |
| 98 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.91329910 |
| 99 | MAF_26560356_Chip-Seq_TH2_Human | 0.89908469 |
| 100 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.89706871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.69634624 |
| 2 | MP0003878_abnormal_ear_physiology | 3.41074056 |
| 3 | MP0005377_hearing/vestibular/ear_phenot | 3.41074056 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 3.35728794 |
| 5 | MP0009785_altered_susceptibility_to | 2.89435395 |
| 6 | MP0006082_CNS_inflammation | 2.80619393 |
| 7 | MP0003763_abnormal_thymus_physiology | 2.44043782 |
| 8 | MP0002163_abnormal_gland_morphology | 2.16614440 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.15090601 |
| 10 | MP0002102_abnormal_ear_morphology | 2.11941528 |
| 11 | MP0001905_abnormal_dopamine_level | 2.11175387 |
| 12 | MP0005410_abnormal_fertilization | 2.05172147 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.02470295 |
| 14 | MP0003866_abnormal_defecation | 1.98999232 |
| 15 | MP0005000_abnormal_immune_tolerance | 1.82796198 |
| 16 | MP0001800_abnormal_humoral_immune | 1.77774766 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 1.75591318 |
| 18 | MP0001835_abnormal_antigen_presentation | 1.73765510 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.72993197 |
| 20 | MP0002420_abnormal_adaptive_immunity | 1.68320189 |
| 21 | MP0002723_abnormal_immune_serum | 1.67936524 |
| 22 | MP0005025_abnormal_response_to | 1.67047287 |
| 23 | MP0001819_abnormal_immune_cell | 1.61083209 |
| 24 | MP0003448_altered_tumor_morphology | 1.58977589 |
| 25 | MP0003786_premature_aging | 1.58413694 |
| 26 | MP0001188_hyperpigmentation | 1.56496940 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.51200311 |
| 28 | MP0001968_abnormal_touch/_nociception | 1.51004917 |
| 29 | MP0002166_altered_tumor_susceptibility | 1.47634327 |
| 30 | MP0008789_abnormal_olfactory_epithelium | 1.46623777 |
| 31 | MP0001485_abnormal_pinna_reflex | 1.38329802 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.34815571 |
| 33 | MP0001790_abnormal_immune_system | 1.34359546 |
| 34 | MP0005387_immune_system_phenotype | 1.34359546 |
| 35 | MP0005379_endocrine/exocrine_gland_phen | 1.34203108 |
| 36 | MP0003787_abnormal_imprinting | 1.34058850 |
| 37 | MP0002837_dystrophic_cardiac_calcinosis | 1.30383162 |
| 38 | MP0002006_tumorigenesis | 1.29781220 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.27472374 |
| 40 | MP0002638_abnormal_pupillary_reflex | 1.26737267 |
| 41 | MP0002405_respiratory_system_inflammati | 1.26396052 |
| 42 | MP0000716_abnormal_immune_system | 1.26160755 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.26051687 |
| 44 | MP0006292_abnormal_olfactory_placode | 1.25891544 |
| 45 | MP0009764_decreased_sensitivity_to | 1.24356746 |
| 46 | MP0001873_stomach_inflammation | 1.21939807 |
| 47 | MP0002452_abnormal_antigen_presenting | 1.20862658 |
| 48 | MP0000703_abnormal_thymus_morphology | 1.20057798 |
| 49 | MP0005389_reproductive_system_phenotype | 1.19833445 |
| 50 | MP0002398_abnormal_bone_marrow | 1.18163015 |
| 51 | MP0001919_abnormal_reproductive_system | 1.17646250 |
| 52 | MP0003045_fibrosis | 1.17514090 |
| 53 | MP0010155_abnormal_intestine_physiology | 1.16948876 |
| 54 | MP0003567_abnormal_fetal_cardiomyocyte | 1.14616199 |
| 55 | MP0002933_joint_inflammation | 1.10077777 |
| 56 | MP0002722_abnormal_immune_system | 1.08329183 |
| 57 | MP0002876_abnormal_thyroid_physiology | 1.07000016 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 1.06673439 |
| 59 | MP0000689_abnormal_spleen_morphology | 1.06055230 |
| 60 | MP0001929_abnormal_gametogenesis | 1.05264317 |
| 61 | MP0008872_abnormal_physiological_respon | 1.05172303 |
| 62 | MP0009763_increased_sensitivity_to | 1.04009811 |
| 63 | MP0004147_increased_porphyrin_level | 1.03531436 |
| 64 | MP0001845_abnormal_inflammatory_respons | 1.03229632 |
| 65 | MP0002909_abnormal_adrenal_gland | 1.00908695 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 1.00275006 |
| 67 | MP0005670_abnormal_white_adipose | 0.98768056 |
| 68 | MP0003137_abnormal_impulse_conducting | 0.96302621 |
| 69 | MP0001984_abnormal_olfaction | 0.94679113 |
| 70 | MP0000685_abnormal_immune_system | 0.93601569 |
| 71 | MP0002210_abnormal_sex_determination | 0.93107615 |
| 72 | MP0002429_abnormal_blood_cell | 0.92654102 |
| 73 | MP0002234_abnormal_pharynx_morphology | 0.92473506 |
| 74 | MP0005394_taste/olfaction_phenotype | 0.91814690 |
| 75 | MP0005499_abnormal_olfactory_system | 0.91814690 |
| 76 | MP0002160_abnormal_reproductive_system | 0.91157668 |
| 77 | MP0001119_abnormal_female_reproductive | 0.91044206 |
| 78 | MP0009765_abnormal_xenobiotic_induced | 0.90008522 |
| 79 | MP0000013_abnormal_adipose_tissue | 0.89791950 |
| 80 | MP0001529_abnormal_vocalization | 0.89426450 |
| 81 | MP0005310_abnormal_salivary_gland | 0.89032014 |
| 82 | MP0009745_abnormal_behavioral_response | 0.86198608 |
| 83 | MP0005253_abnormal_eye_physiology | 0.85867958 |
| 84 | MP0010307_abnormal_tumor_latency | 0.85164449 |
| 85 | MP0003693_abnormal_embryo_hatching | 0.83467346 |
| 86 | MP0006276_abnormal_autonomic_nervous | 0.83392470 |
| 87 | MP0002736_abnormal_nociception_after | 0.83310987 |
| 88 | MP0003136_yellow_coat_color | 0.83248106 |
| 89 | MP0002095_abnormal_skin_pigmentation | 0.82209797 |
| 90 | MP0009379_abnormal_foot_pigmentation | 0.81616152 |
| 91 | MP0008873_increased_physiological_sensi | 0.81381954 |
| 92 | MP0003283_abnormal_digestive_organ | 0.81209962 |
| 93 | MP0003718_maternal_effect | 0.79669826 |
| 94 | MP0006054_spinal_hemorrhage | 0.78926336 |
| 95 | MP0003698_abnormal_male_reproductive | 0.78216131 |
| 96 | MP0001986_abnormal_taste_sensitivity | 0.77870895 |
| 97 | MP0008469_abnormal_protein_level | 0.77084244 |
| 98 | MP0008875_abnormal_xenobiotic_pharmacok | 0.76925824 |
| 99 | MP0001881_abnormal_mammary_gland | 0.72383155 |
| 100 | MP0004957_abnormal_blastocyst_morpholog | 0.70968229 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 4.93691857 |
| 2 | Abnormality of T cell number (HP:0011839) | 4.79292292 |
| 3 | Aplastic anemia (HP:0001915) | 4.66417388 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 4.49175609 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.41950529 |
| 6 | Mitochondrial inheritance (HP:0001427) | 4.30465628 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.04931141 |
| 8 | Autoimmune hemolytic anemia (HP:0001890) | 3.97778260 |
| 9 | IgG deficiency (HP:0004315) | 3.93267471 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.78454633 |
| 11 | Combined immunodeficiency (HP:0005387) | 3.67787645 |
| 12 | Acute encephalopathy (HP:0006846) | 3.66421749 |
| 13 | Increased IgM level (HP:0003496) | 3.62818719 |
| 14 | Abnormality of T cells (HP:0002843) | 3.56515668 |
| 15 | Increased CSF lactate (HP:0002490) | 3.53737758 |
| 16 | Abnormality of eosinophils (HP:0001879) | 3.52620827 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.52304073 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.44382186 |
| 19 | Abnormality of midbrain morphology (HP:0002418) | 3.44145041 |
| 20 | Molar tooth sign on MRI (HP:0002419) | 3.44145041 |
| 21 | Hepatic necrosis (HP:0002605) | 3.38759561 |
| 22 | Hypoproteinemia (HP:0003075) | 3.30677773 |
| 23 | Thyroiditis (HP:0100646) | 3.27035526 |
| 24 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.18671800 |
| 25 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.18671800 |
| 26 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.16769731 |
| 27 | Pancreatic fibrosis (HP:0100732) | 3.14490843 |
| 28 | Pancreatic cysts (HP:0001737) | 3.13617533 |
| 29 | Eosinophilia (HP:0001880) | 3.09603113 |
| 30 | Cerebral edema (HP:0002181) | 3.08565691 |
| 31 | Type 2 muscle fiber atrophy (HP:0003554) | 2.88646145 |
| 32 | Increased intramyocellular lipid droplets (HP:0012240) | 2.88196030 |
| 33 | Increased hepatocellular lipid droplets (HP:0006565) | 2.88074881 |
| 34 | True hermaphroditism (HP:0010459) | 2.77212249 |
| 35 | Hypoplasia of the thymus (HP:0000778) | 2.72937910 |
| 36 | Renal Fanconi syndrome (HP:0001994) | 2.70214165 |
| 37 | Leukocytosis (HP:0001974) | 2.70153325 |
| 38 | Stomatitis (HP:0010280) | 2.63268178 |
| 39 | Autoimmune thrombocytopenia (HP:0001973) | 2.63069462 |
| 40 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.57190070 |
| 41 | Muscle fiber atrophy (HP:0100295) | 2.57175326 |
| 42 | Granulocytopenia (HP:0001913) | 2.53684976 |
| 43 | Recurrent bronchitis (HP:0002837) | 2.52927412 |
| 44 | Short tibia (HP:0005736) | 2.52831340 |
| 45 | Optic disc pallor (HP:0000543) | 2.45833637 |
| 46 | Lipid accumulation in hepatocytes (HP:0006561) | 2.38087741 |
| 47 | Lactic acidosis (HP:0003128) | 2.37109277 |
| 48 | Abnormal albumin level (HP:0012116) | 2.37051966 |
| 49 | Hypoalbuminemia (HP:0003073) | 2.37051966 |
| 50 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.34727039 |
| 51 | Abnormal biliary tract physiology (HP:0012439) | 2.33939299 |
| 52 | Bile duct proliferation (HP:0001408) | 2.33939299 |
| 53 | Generalized aminoaciduria (HP:0002909) | 2.31376114 |
| 54 | Recurrent cutaneous fungal infections (HP:0011370) | 2.26157121 |
| 55 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.26157121 |
| 56 | Amyotrophic lateral sclerosis (HP:0007354) | 2.21756060 |
| 57 | Increased serum lactate (HP:0002151) | 2.20138239 |
| 58 | Chronic diarrhea (HP:0002028) | 2.19918457 |
| 59 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.18434619 |
| 60 | Increased muscle lipid content (HP:0009058) | 2.14809651 |
| 61 | Abnormality of T cell physiology (HP:0011840) | 2.14510406 |
| 62 | Renal cortical cysts (HP:0000803) | 2.10381849 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.09715359 |
| 64 | Encephalitis (HP:0002383) | 2.09620896 |
| 65 | Pustule (HP:0200039) | 2.09294097 |
| 66 | Decreased central vision (HP:0007663) | 2.09091756 |
| 67 | Attenuation of retinal blood vessels (HP:0007843) | 2.07890884 |
| 68 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.05992622 |
| 69 | Congenital stationary night blindness (HP:0007642) | 2.02244198 |
| 70 | Medial flaring of the eyebrow (HP:0010747) | 2.02118980 |
| 71 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.01025925 |
| 72 | Type I transferrin isoform profile (HP:0003642) | 2.01012766 |
| 73 | Nephronophthisis (HP:0000090) | 2.00902630 |
| 74 | Colon cancer (HP:0003003) | 2.00014461 |
| 75 | Panhypogammaglobulinemia (HP:0003139) | 1.98059004 |
| 76 | Lymphopenia (HP:0001888) | 1.96106467 |
| 77 | Respiratory failure (HP:0002878) | 1.96032352 |
| 78 | Sclerocornea (HP:0000647) | 1.95870723 |
| 79 | Exercise intolerance (HP:0003546) | 1.94532781 |
| 80 | Abnormality of the prostate (HP:0008775) | 1.94407751 |
| 81 | Abnormality of B cell number (HP:0010975) | 1.94265960 |
| 82 | Cystic liver disease (HP:0006706) | 1.91562724 |
| 83 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.88293619 |
| 84 | Abnormal protein glycosylation (HP:0012346) | 1.87289628 |
| 85 | Abnormal glycosylation (HP:0012345) | 1.87289628 |
| 86 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.87289628 |
| 87 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.87289628 |
| 88 | Cerebral hypomyelination (HP:0006808) | 1.86543123 |
| 89 | Hemiplegia (HP:0002301) | 1.86387235 |
| 90 | CNS demyelination (HP:0007305) | 1.84117844 |
| 91 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.83335882 |
| 92 | Pancytopenia (HP:0001876) | 1.82947619 |
| 93 | Exertional dyspnea (HP:0002875) | 1.82249804 |
| 94 | Tetany (HP:0001281) | 1.82121200 |
| 95 | IgM deficiency (HP:0002850) | 1.79623852 |
| 96 | Abnormality of the renal cortex (HP:0011035) | 1.79345891 |
| 97 | Leukodystrophy (HP:0002415) | 1.79003546 |
| 98 | Nephrogenic diabetes insipidus (HP:0009806) | 1.73261833 |
| 99 | Abnormality of magnesium homeostasis (HP:0004921) | 1.72339364 |
| 100 | Abolished electroretinogram (ERG) (HP:0000550) | 1.70843804 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 5.50410814 |
| 2 | TESK2 | 5.00066606 |
| 3 | TXK | 4.09702228 |
| 4 | MAP4K2 | 4.02542756 |
| 5 | VRK2 | 2.98630221 |
| 6 | TESK1 | 2.85012660 |
| 7 | ADRBK2 | 2.38753340 |
| 8 | ZAK | 2.37111702 |
| 9 | WNK4 | 2.35526726 |
| 10 | BCKDK | 2.34880301 |
| 11 | BUB1 | 2.33112047 |
| 12 | LIMK1 | 2.05853110 |
| 13 | NUAK1 | 1.89601163 |
| 14 | TIE1 | 1.82211436 |
| 15 | VRK1 | 1.67198480 |
| 16 | MAP4K1 | 1.66134435 |
| 17 | TRIM28 | 1.64615977 |
| 18 | ITK | 1.63780525 |
| 19 | FES | 1.60963570 |
| 20 | STK16 | 1.58933118 |
| 21 | PIK3CA | 1.55476428 |
| 22 | OXSR1 | 1.50459580 |
| 23 | STK39 | 1.47133091 |
| 24 | SRPK1 | 1.38543650 |
| 25 | BMPR1B | 1.37850852 |
| 26 | PLK4 | 1.27535137 |
| 27 | EIF2AK3 | 1.25754225 |
| 28 | PRKCQ | 1.23439333 |
| 29 | GRK1 | 1.22857643 |
| 30 | MAP2K7 | 1.18559248 |
| 31 | MAPKAPK3 | 1.17367100 |
| 32 | GRK7 | 1.12381891 |
| 33 | IKBKE | 1.10544505 |
| 34 | TLK1 | 1.03129420 |
| 35 | MAP3K12 | 1.01475064 |
| 36 | TAOK3 | 1.00491115 |
| 37 | DAPK1 | 0.94138355 |
| 38 | BCR | 0.91885117 |
| 39 | LCK | 0.90631231 |
| 40 | CSK | 0.90525982 |
| 41 | INSRR | 0.85783285 |
| 42 | MAP3K11 | 0.85167830 |
| 43 | ARAF | 0.82595120 |
| 44 | SYK | 0.82380794 |
| 45 | WNK3 | 0.81799160 |
| 46 | FRK | 0.81569183 |
| 47 | ZAP70 | 0.79700874 |
| 48 | PINK1 | 0.79533470 |
| 49 | PIM2 | 0.79034672 |
| 50 | PIK3CG | 0.76131678 |
| 51 | TAF1 | 0.75293234 |
| 52 | PLK2 | 0.72658675 |
| 53 | TYRO3 | 0.66377728 |
| 54 | RPS6KA5 | 0.66130003 |
| 55 | IKBKB | 0.63566436 |
| 56 | GRK5 | 0.59404210 |
| 57 | LYN | 0.57503826 |
| 58 | MST4 | 0.57065468 |
| 59 | DYRK2 | 0.56216488 |
| 60 | TEC | 0.54223582 |
| 61 | EIF2AK2 | 0.51796707 |
| 62 | CSF1R | 0.47625854 |
| 63 | CSNK1G3 | 0.47539858 |
| 64 | AURKA | 0.46884140 |
| 65 | MAP2K6 | 0.44008523 |
| 66 | CSNK2A1 | 0.43711010 |
| 67 | MYLK | 0.41919906 |
| 68 | NEK1 | 0.40689526 |
| 69 | PRKCI | 0.40277438 |
| 70 | CSNK1A1 | 0.39848032 |
| 71 | PRKCE | 0.39126867 |
| 72 | BRSK2 | 0.38384898 |
| 73 | PDK2 | 0.37862268 |
| 74 | PRKCG | 0.37715747 |
| 75 | JAK3 | 0.37686286 |
| 76 | PLK1 | 0.36768757 |
| 77 | FYN | 0.36543019 |
| 78 | IGF1R | 0.36354856 |
| 79 | INSR | 0.36336500 |
| 80 | MAP3K4 | 0.34669347 |
| 81 | AURKB | 0.34213212 |
| 82 | MAPK13 | 0.34052980 |
| 83 | CSNK1A1L | 0.33922412 |
| 84 | CLK1 | 0.33844429 |
| 85 | BTK | 0.33221557 |
| 86 | PRKCA | 0.33015328 |
| 87 | BRAF | 0.32723014 |
| 88 | ROCK1 | 0.32667389 |
| 89 | ADRBK1 | 0.32156700 |
| 90 | RPS6KA4 | 0.31192469 |
| 91 | MARK3 | 0.30770855 |
| 92 | NEK6 | 0.29509389 |
| 93 | EPHB2 | 0.28806097 |
| 94 | NME1 | 0.27647182 |
| 95 | PLK3 | 0.27230476 |
| 96 | CSNK2A2 | 0.27173897 |
| 97 | PRKACA | 0.27037490 |
| 98 | TNIK | 0.26956490 |
| 99 | KIT | 0.26175961 |
| 100 | OBSCN | 0.25387713 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.33636936 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.94296989 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.68540210 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.35240682 |
| 5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.99358165 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.95769299 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.90633784 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.46290971 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.39156781 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.35421546 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.19131123 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.07059081 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.98898746 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.92205981 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.90349519 |
| 16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.86737946 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.81991714 |
| 18 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.67716790 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.66586688 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.63931178 |
| 21 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.62141111 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.58254590 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.54260666 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.47489357 |
| 25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.34141768 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.33620824 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.32251261 |
| 28 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.28328806 |
| 29 | Sulfur relay system_Homo sapiens_hsa04122 | 1.18444629 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.11873648 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08519722 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.07139475 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.01651227 |
| 34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.99045599 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 0.95337225 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 0.91544650 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 0.91134709 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 0.90888743 |
| 39 | Salmonella infection_Homo sapiens_hsa05132 | 0.87851653 |
| 40 | Measles_Homo sapiens_hsa05162 | 0.85733480 |
| 41 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.80180512 |
| 42 | Shigellosis_Homo sapiens_hsa05131 | 0.79827030 |
| 43 | RNA degradation_Homo sapiens_hsa03018 | 0.78678284 |
| 44 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74528690 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74347909 |
| 46 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73808929 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.73171901 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.72734974 |
| 49 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71951350 |
| 50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.68803191 |
| 51 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68221504 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67147071 |
| 53 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.66696529 |
| 54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.65290571 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65286360 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.63750442 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.62699560 |
| 58 | Mismatch repair_Homo sapiens_hsa03430 | 0.62435093 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62418485 |
| 60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60644638 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.58736778 |
| 62 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.57083965 |
| 63 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56401278 |
| 64 | Asthma_Homo sapiens_hsa05310 | 0.56097506 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55761120 |
| 66 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.54898246 |
| 67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54776085 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52051861 |
| 69 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51615690 |
| 70 | Base excision repair_Homo sapiens_hsa03410 | 0.47084811 |
| 71 | DNA replication_Homo sapiens_hsa03030 | 0.46444768 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46100999 |
| 73 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45724006 |
| 74 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.44125014 |
| 75 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.43266562 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.43222886 |
| 77 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42364452 |
| 78 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.40950211 |
| 79 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.40674899 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.37845035 |
| 81 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.37338093 |
| 82 | Nicotine addiction_Homo sapiens_hsa05033 | 0.37020877 |
| 83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34779156 |
| 84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.31928476 |
| 85 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.31703145 |
| 86 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.30880730 |
| 87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.29978793 |
| 88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.29196400 |
| 89 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.28850515 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.27962322 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27139399 |
| 92 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.26105516 |
| 93 | Retinol metabolism_Homo sapiens_hsa00830 | 0.25908820 |
| 94 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25793135 |
| 95 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.22201284 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.21866087 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.21340105 |
| 98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.21187229 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.18105089 |
| 100 | HTLV-I infection_Homo sapiens_hsa05166 | 0.17519162 |

