

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.57741988 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.12957103 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.12957103 |
| 4 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.89675385 |
| 5 | proteasome assembly (GO:0043248) | 4.82007166 |
| 6 | DNA deamination (GO:0045006) | 4.47185262 |
| 7 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.26789415 |
| 8 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.00656494 |
| 9 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.98946356 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.94178574 |
| 11 | cullin deneddylation (GO:0010388) | 3.94028412 |
| 12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.85816380 |
| 13 | electron transport chain (GO:0022900) | 3.79249296 |
| 14 | respiratory electron transport chain (GO:0022904) | 3.77485065 |
| 15 | mannosylation (GO:0097502) | 3.72104592 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.62114708 |
| 17 | protein neddylation (GO:0045116) | 3.61209380 |
| 18 | sequestering of actin monomers (GO:0042989) | 3.59338699 |
| 19 | L-methionine salvage (GO:0071267) | 3.58615832 |
| 20 | L-methionine biosynthetic process (GO:0071265) | 3.58615832 |
| 21 | amino acid salvage (GO:0043102) | 3.58615832 |
| 22 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.56682174 |
| 23 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.56682174 |
| 24 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.56682174 |
| 25 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.55562341 |
| 26 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.49715725 |
| 27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.49715725 |
| 28 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.49144624 |
| 29 | negative regulation of heart rate (GO:0010459) | 3.48781092 |
| 30 | protein deneddylation (GO:0000338) | 3.47811992 |
| 31 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.46316660 |
| 32 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.44220955 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.41706336 |
| 34 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.41706336 |
| 35 | peptidyl-histidine modification (GO:0018202) | 3.41678421 |
| 36 | negative regulation of ligase activity (GO:0051352) | 3.41116158 |
| 37 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.41116158 |
| 38 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.38764314 |
| 39 | rRNA modification (GO:0000154) | 3.37338695 |
| 40 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.36928648 |
| 41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.36928648 |
| 42 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35873615 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35873615 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.34126853 |
| 45 | GPI anchor biosynthetic process (GO:0006506) | 3.27380533 |
| 46 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.25988303 |
| 47 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.21264765 |
| 48 | NADH dehydrogenase complex assembly (GO:0010257) | 3.21264765 |
| 49 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.21264765 |
| 50 | respiratory chain complex IV assembly (GO:0008535) | 3.16983009 |
| 51 | protein complex biogenesis (GO:0070271) | 3.14175457 |
| 52 | GPI anchor metabolic process (GO:0006505) | 3.09008409 |
| 53 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.08470059 |
| 54 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.08119541 |
| 55 | hydrogen ion transmembrane transport (GO:1902600) | 3.07177906 |
| 56 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.01377230 |
| 57 | fucose catabolic process (GO:0019317) | 2.99085288 |
| 58 | L-fucose metabolic process (GO:0042354) | 2.99085288 |
| 59 | L-fucose catabolic process (GO:0042355) | 2.99085288 |
| 60 | intracellular protein transmembrane import (GO:0044743) | 2.93836502 |
| 61 | inner mitochondrial membrane organization (GO:0007007) | 2.93108960 |
| 62 | maturation of 5.8S rRNA (GO:0000460) | 2.92983262 |
| 63 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.92774918 |
| 64 | regulation of cellular amine metabolic process (GO:0033238) | 2.91576168 |
| 65 | proton transport (GO:0015992) | 2.91220175 |
| 66 | cytidine metabolic process (GO:0046087) | 2.90505480 |
| 67 | cytidine catabolic process (GO:0006216) | 2.90505480 |
| 68 | cytidine deamination (GO:0009972) | 2.90505480 |
| 69 | hydrogen transport (GO:0006818) | 2.89890649 |
| 70 | chaperone-mediated protein transport (GO:0072321) | 2.86964001 |
| 71 | adult feeding behavior (GO:0008343) | 2.84675235 |
| 72 | regulation of transmission of nerve impulse (GO:0051969) | 2.84664460 |
| 73 | S-adenosylmethionine metabolic process (GO:0046500) | 2.84209014 |
| 74 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.82789997 |
| 75 | C-terminal protein lipidation (GO:0006501) | 2.82166418 |
| 76 | ATP biosynthetic process (GO:0006754) | 2.80671207 |
| 77 | positive regulation of ligase activity (GO:0051351) | 2.77788908 |
| 78 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.77622765 |
| 79 | histone H2A acetylation (GO:0043968) | 2.77129295 |
| 80 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.76176582 |
| 81 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.76133433 |
| 82 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.71250594 |
| 83 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.70653750 |
| 84 | aldehyde catabolic process (GO:0046185) | 2.68860906 |
| 85 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.68792253 |
| 86 | GTP biosynthetic process (GO:0006183) | 2.67969365 |
| 87 | positive regulation of catecholamine secretion (GO:0033605) | 2.66507807 |
| 88 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.66315127 |
| 89 | negative regulation of bone resorption (GO:0045779) | 2.64332121 |
| 90 | regulation of interleukin-8 secretion (GO:2000482) | 2.63785843 |
| 91 | methionine biosynthetic process (GO:0009086) | 2.62861758 |
| 92 | positive regulation of cell cycle arrest (GO:0071158) | 2.61439463 |
| 93 | C-terminal protein amino acid modification (GO:0018410) | 2.60402130 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.57032325 |
| 95 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.52642862 |
| 96 | metallo-sulfur cluster assembly (GO:0031163) | 2.52312681 |
| 97 | iron-sulfur cluster assembly (GO:0016226) | 2.52312681 |
| 98 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.49273074 |
| 99 | mast cell degranulation (GO:0043303) | 2.49064855 |
| 100 | mast cell activation involved in immune response (GO:0002279) | 2.49064855 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35356478 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.19687128 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83030317 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.52993280 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.32986699 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.09861063 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.86647496 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.83794318 |
| 9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.75427642 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.72939648 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.47860135 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.47050343 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.43906714 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.41601606 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.38130947 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.32295161 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.31801415 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.28719404 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.18899811 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.04521209 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.96622751 |
| 22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.93757525 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.92642924 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.91297224 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.86270365 |
| 26 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.84620842 |
| 27 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.84424446 |
| 28 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.81273943 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.78694763 |
| 30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.76708309 |
| 31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.72287681 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.71731824 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.68377972 |
| 34 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.61295484 |
| 35 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.57534666 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56878721 |
| 37 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.52116092 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.48370434 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.45034892 |
| 40 | AR_20517297_ChIP-Seq_VCAP_Human | 1.42443313 |
| 41 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.42339732 |
| 42 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.41896271 |
| 43 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.38269702 |
| 44 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.33773073 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32794513 |
| 46 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.32077432 |
| 47 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.31942518 |
| 48 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.29239876 |
| 49 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.28758144 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.28457949 |
| 51 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27941649 |
| 52 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27941649 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.26500634 |
| 54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.25909451 |
| 55 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.25148210 |
| 56 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23886322 |
| 57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.22952584 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.22952584 |
| 59 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21523164 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.20953952 |
| 61 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.19712486 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.16871495 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16757218 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.13778709 |
| 65 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.11088260 |
| 66 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.09601525 |
| 67 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.09207029 |
| 68 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.07224917 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06803627 |
| 70 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.06096309 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06062418 |
| 72 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06062418 |
| 73 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.05936903 |
| 74 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.03852381 |
| 75 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03399747 |
| 76 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.01771371 |
| 77 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00041225 |
| 78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99265772 |
| 79 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98658922 |
| 80 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.97064372 |
| 81 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.96713415 |
| 82 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.96671073 |
| 83 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.95685603 |
| 84 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.94784738 |
| 85 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.94354251 |
| 86 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.94327202 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94093953 |
| 88 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.93668461 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.92856960 |
| 90 | GATA3_26560356_Chip-Seq_TH1_Human | 0.92218054 |
| 91 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.92053570 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91482565 |
| 93 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.91106693 |
| 94 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90485236 |
| 95 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90451664 |
| 96 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.89478811 |
| 97 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87284762 |
| 98 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.86846195 |
| 99 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85958934 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85786008 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 4.13112211 |
| 2 | MP0003011_delayed_dark_adaptation | 3.07887134 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 2.80441371 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.71338151 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 2.65588726 |
| 6 | MP0005671_abnormal_response_to | 2.57584730 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.53316338 |
| 8 | MP0003724_increased_susceptibility_to | 2.34785830 |
| 9 | MP0002148_abnormal_hypersensitivity_rea | 2.28111549 |
| 10 | MP0009785_altered_susceptibility_to | 2.27610994 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.27260058 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.25997720 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 2.21684435 |
| 14 | MP0002102_abnormal_ear_morphology | 1.99611412 |
| 15 | MP0003195_calcinosis | 1.97400008 |
| 16 | MP0003786_premature_aging | 1.90768484 |
| 17 | MP0006035_abnormal_mitochondrial_morpho | 1.88493589 |
| 18 | MP0005253_abnormal_eye_physiology | 1.85045596 |
| 19 | MP0008995_early_reproductive_senescence | 1.73666499 |
| 20 | MP0006036_abnormal_mitochondrial_physio | 1.66955284 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.62848968 |
| 22 | MP0008007_abnormal_cellular_replicative | 1.59839568 |
| 23 | MP0009764_decreased_sensitivity_to | 1.57164333 |
| 24 | MP0006082_CNS_inflammation | 1.47373197 |
| 25 | MP0003866_abnormal_defecation | 1.45778436 |
| 26 | MP0003880_abnormal_central_pattern | 1.45469587 |
| 27 | MP0004147_increased_porphyrin_level | 1.44507495 |
| 28 | MP0008877_abnormal_DNA_methylation | 1.43309265 |
| 29 | MP0005646_abnormal_pituitary_gland | 1.41983558 |
| 30 | MP0001800_abnormal_humoral_immune | 1.40886500 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.39499496 |
| 32 | MP0008058_abnormal_DNA_repair | 1.36349499 |
| 33 | MP0005332_abnormal_amino_acid | 1.35560006 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.35157035 |
| 35 | MP0001905_abnormal_dopamine_level | 1.34859717 |
| 36 | MP0002277_abnormal_respiratory_mucosa | 1.32847717 |
| 37 | MP0004145_abnormal_muscle_electrophysio | 1.32505823 |
| 38 | MP0003186_abnormal_redox_activity | 1.30233262 |
| 39 | MP0005167_abnormal_blood-brain_barrier | 1.29820186 |
| 40 | MP0006276_abnormal_autonomic_nervous | 1.27330833 |
| 41 | MP0008872_abnormal_physiological_respon | 1.25195875 |
| 42 | MP0001873_stomach_inflammation | 1.24442822 |
| 43 | MP0002837_dystrophic_cardiac_calcinosis | 1.23175035 |
| 44 | MP0002254_reproductive_system_inflammat | 1.21955327 |
| 45 | MP0005000_abnormal_immune_tolerance | 1.20894169 |
| 46 | MP0004885_abnormal_endolymph | 1.18973828 |
| 47 | MP0002876_abnormal_thyroid_physiology | 1.12872636 |
| 48 | MP0003718_maternal_effect | 1.11476121 |
| 49 | MP0002452_abnormal_antigen_presenting | 1.10485226 |
| 50 | MP0005387_immune_system_phenotype | 1.09253984 |
| 51 | MP0001790_abnormal_immune_system | 1.09253984 |
| 52 | MP0002736_abnormal_nociception_after | 1.07889039 |
| 53 | MP0008775_abnormal_heart_ventricle | 1.05697440 |
| 54 | MP0002723_abnormal_immune_serum | 1.05351681 |
| 55 | MP0003172_abnormal_lysosome_physiology | 1.00810336 |
| 56 | MP0001485_abnormal_pinna_reflex | 0.98981644 |
| 57 | MP0003693_abnormal_embryo_hatching | 0.98696411 |
| 58 | MP0003137_abnormal_impulse_conducting | 0.98659370 |
| 59 | MP0000613_abnormal_salivary_gland | 0.97819123 |
| 60 | MP0001819_abnormal_immune_cell | 0.97689104 |
| 61 | MP0002733_abnormal_thermal_nociception | 0.96651968 |
| 62 | MP0003787_abnormal_imprinting | 0.94997850 |
| 63 | MP0001764_abnormal_homeostasis | 0.93714621 |
| 64 | MP0000685_abnormal_immune_system | 0.93187011 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 0.92989057 |
| 66 | MP0002420_abnormal_adaptive_immunity | 0.91579156 |
| 67 | MP0002234_abnormal_pharynx_morphology | 0.91532399 |
| 68 | MP0004215_abnormal_myocardial_fiber | 0.90943539 |
| 69 | MP0005389_reproductive_system_phenotype | 0.90485889 |
| 70 | MP0001970_abnormal_pain_threshold | 0.90400928 |
| 71 | MP0006292_abnormal_olfactory_placode | 0.89907940 |
| 72 | MP0001529_abnormal_vocalization | 0.89440713 |
| 73 | MP0001853_heart_inflammation | 0.89411906 |
| 74 | MP0000358_abnormal_cell_content/ | 0.89195302 |
| 75 | MP0008961_abnormal_basal_metabolism | 0.89191189 |
| 76 | MP0005085_abnormal_gallbladder_physiolo | 0.89014652 |
| 77 | MP0010386_abnormal_urinary_bladder | 0.88675443 |
| 78 | MP0003878_abnormal_ear_physiology | 0.86533972 |
| 79 | MP0005377_hearing/vestibular/ear_phenot | 0.86533972 |
| 80 | MP0004957_abnormal_blastocyst_morpholog | 0.85993400 |
| 81 | MP0004084_abnormal_cardiac_muscle | 0.85027110 |
| 82 | MP0003252_abnormal_bile_duct | 0.84963638 |
| 83 | MP0008469_abnormal_protein_level | 0.84563066 |
| 84 | MP0005319_abnormal_enzyme/_coenzyme | 0.84317342 |
| 85 | MP0009333_abnormal_splenocyte_physiolog | 0.83584418 |
| 86 | MP0002638_abnormal_pupillary_reflex | 0.81961185 |
| 87 | MP0002751_abnormal_autonomic_nervous | 0.81878171 |
| 88 | MP0001845_abnormal_inflammatory_respons | 0.81557305 |
| 89 | MP0010155_abnormal_intestine_physiology | 0.80412282 |
| 90 | MP0008873_increased_physiological_sensi | 0.79842778 |
| 91 | MP0001501_abnormal_sleep_pattern | 0.79810113 |
| 92 | MP0001984_abnormal_olfaction | 0.79519065 |
| 93 | MP0002272_abnormal_nervous_system | 0.78298894 |
| 94 | MP0004142_abnormal_muscle_tone | 0.78223277 |
| 95 | MP0002090_abnormal_vision | 0.76634881 |
| 96 | MP0001919_abnormal_reproductive_system | 0.75382109 |
| 97 | MP0005410_abnormal_fertilization | 0.74477580 |
| 98 | MP0000647_abnormal_sebaceous_gland | 0.72760222 |
| 99 | MP0003436_decreased_susceptibility_to | 0.72541379 |
| 100 | MP0005365_abnormal_bile_salt | 0.70272012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 4.37122172 |
| 2 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.29979394 |
| 3 | Abnormality of alanine metabolism (HP:0010916) | 4.29979394 |
| 4 | Hyperalaninemia (HP:0003348) | 4.29979394 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.21578061 |
| 6 | Acute encephalopathy (HP:0006846) | 3.93285801 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.83842249 |
| 8 | Increased CSF lactate (HP:0002490) | 3.83484370 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.74865175 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.68600882 |
| 11 | Abolished electroretinogram (ERG) (HP:0000550) | 3.62783876 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.56789357 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.56789357 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.52591546 |
| 15 | Hepatic necrosis (HP:0002605) | 3.47972809 |
| 16 | Decreased central vision (HP:0007663) | 3.25564190 |
| 17 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.24172629 |
| 18 | Type I transferrin isoform profile (HP:0003642) | 3.20821126 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 3.20426595 |
| 20 | Short tibia (HP:0005736) | 3.13266400 |
| 21 | Cerebral edema (HP:0002181) | 3.10894900 |
| 22 | Lipid accumulation in hepatocytes (HP:0006561) | 3.08775975 |
| 23 | Hypoproteinemia (HP:0003075) | 3.00751644 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.97429106 |
| 25 | Increased serum lactate (HP:0002151) | 2.90466703 |
| 26 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.81686292 |
| 27 | Abnormality of the anterior horn cell (HP:0006802) | 2.80582103 |
| 28 | Degeneration of anterior horn cells (HP:0002398) | 2.80582103 |
| 29 | Hypothermia (HP:0002045) | 2.73619485 |
| 30 | Lactic acidosis (HP:0003128) | 2.72867947 |
| 31 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.69219847 |
| 32 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.69219847 |
| 33 | Abnormality of serum amino acid levels (HP:0003112) | 2.68868841 |
| 34 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.67625559 |
| 35 | Abnormal protein glycosylation (HP:0012346) | 2.67625559 |
| 36 | Abnormal glycosylation (HP:0012345) | 2.67625559 |
| 37 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.67625559 |
| 38 | Nephronophthisis (HP:0000090) | 2.64388793 |
| 39 | Optic disc pallor (HP:0000543) | 2.61692149 |
| 40 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.55499241 |
| 41 | Aplastic anemia (HP:0001915) | 2.49317198 |
| 42 | Renal cortical cysts (HP:0000803) | 2.44919453 |
| 43 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.41045315 |
| 44 | Pancreatic cysts (HP:0001737) | 2.39281566 |
| 45 | Abnormality of the labia minora (HP:0012880) | 2.38663736 |
| 46 | Methylmalonic acidemia (HP:0002912) | 2.38354018 |
| 47 | Delayed CNS myelination (HP:0002188) | 2.37321763 |
| 48 | True hermaphroditism (HP:0010459) | 2.34898028 |
| 49 | Lethargy (HP:0001254) | 2.33873886 |
| 50 | Type 2 muscle fiber atrophy (HP:0003554) | 2.31959522 |
| 51 | Respiratory failure (HP:0002878) | 2.30514316 |
| 52 | Methylmalonic aciduria (HP:0012120) | 2.29827388 |
| 53 | Attenuation of retinal blood vessels (HP:0007843) | 2.29594342 |
| 54 | CNS demyelination (HP:0007305) | 2.25768033 |
| 55 | Retinal dysplasia (HP:0007973) | 2.24578565 |
| 56 | Stomach cancer (HP:0012126) | 2.23022673 |
| 57 | Abnormality of the prostate (HP:0008775) | 2.22762802 |
| 58 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.21760378 |
| 59 | Constricted visual fields (HP:0001133) | 2.17792807 |
| 60 | Generalized aminoaciduria (HP:0002909) | 2.17740693 |
| 61 | Medial flaring of the eyebrow (HP:0010747) | 2.16930953 |
| 62 | Leukodystrophy (HP:0002415) | 2.16201366 |
| 63 | IgG deficiency (HP:0004315) | 2.15250304 |
| 64 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.12416863 |
| 65 | Pancreatic fibrosis (HP:0100732) | 2.12192925 |
| 66 | Increased intramyocellular lipid droplets (HP:0012240) | 2.10904896 |
| 67 | Hyperglycinuria (HP:0003108) | 2.10152232 |
| 68 | Facial diplegia (HP:0001349) | 2.09122920 |
| 69 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.08809202 |
| 70 | Exertional dyspnea (HP:0002875) | 2.07821717 |
| 71 | Abnormality of the renal medulla (HP:0100957) | 2.03961509 |
| 72 | Severe combined immunodeficiency (HP:0004430) | 2.03515926 |
| 73 | Abnormal albumin level (HP:0012116) | 1.98755388 |
| 74 | Hypoalbuminemia (HP:0003073) | 1.98755388 |
| 75 | Panhypogammaglobulinemia (HP:0003139) | 1.98565508 |
| 76 | Microvesicular hepatic steatosis (HP:0001414) | 1.96637737 |
| 77 | Renal Fanconi syndrome (HP:0001994) | 1.94017308 |
| 78 | Tongue fasciculations (HP:0001308) | 1.93338133 |
| 79 | Cerebral hypomyelination (HP:0006808) | 1.90787995 |
| 80 | Exercise intolerance (HP:0003546) | 1.89325599 |
| 81 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.87873761 |
| 82 | Dicarboxylic aciduria (HP:0003215) | 1.87873761 |
| 83 | Cerebral palsy (HP:0100021) | 1.86684766 |
| 84 | Congenital, generalized hypertrichosis (HP:0004540) | 1.85395721 |
| 85 | Abnormality of the renal cortex (HP:0011035) | 1.83229529 |
| 86 | Testicular atrophy (HP:0000029) | 1.83158350 |
| 87 | Abnormality of glycine metabolism (HP:0010895) | 1.80264006 |
| 88 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.80264006 |
| 89 | Dyschromatopsia (HP:0007641) | 1.78512010 |
| 90 | Type II lissencephaly (HP:0007260) | 1.76300053 |
| 91 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.76146805 |
| 92 | Emotional lability (HP:0000712) | 1.76010364 |
| 93 | Autoamputation (HP:0001218) | 1.74937126 |
| 94 | Muscle fiber atrophy (HP:0100295) | 1.74655648 |
| 95 | Increased muscle lipid content (HP:0009058) | 1.72982456 |
| 96 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.72606132 |
| 97 | Increased corneal curvature (HP:0100692) | 1.72267093 |
| 98 | Keratoconus (HP:0000563) | 1.72267093 |
| 99 | Cerebellar dysplasia (HP:0007033) | 1.71950264 |
| 100 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.70516290 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR1B | 4.00316296 |
| 2 | TIE1 | 3.55554887 |
| 3 | MAP4K2 | 3.08302200 |
| 4 | ZAK | 3.01030285 |
| 5 | TLK1 | 2.91263943 |
| 6 | MAP3K12 | 2.59392345 |
| 7 | TAOK3 | 2.55203230 |
| 8 | BUB1 | 2.47353077 |
| 9 | NUAK1 | 2.33999829 |
| 10 | CDK8 | 2.22322658 |
| 11 | BMPR2 | 2.12622645 |
| 12 | CDK19 | 2.08265962 |
| 13 | STK16 | 2.07818126 |
| 14 | MAPKAPK3 | 2.00688206 |
| 15 | VRK2 | 1.99056424 |
| 16 | GRK1 | 1.98639219 |
| 17 | VRK1 | 1.91433455 |
| 18 | BCKDK | 1.90105306 |
| 19 | ADRBK2 | 1.88263166 |
| 20 | DAPK1 | 1.68724998 |
| 21 | TRIM28 | 1.65873298 |
| 22 | EIF2AK3 | 1.58702409 |
| 23 | MST4 | 1.58557693 |
| 24 | FES | 1.58145484 |
| 25 | TGFBR1 | 1.55412276 |
| 26 | KIT | 1.50223155 |
| 27 | SRPK1 | 1.48457750 |
| 28 | CSNK1G3 | 1.45515647 |
| 29 | TXK | 1.33480454 |
| 30 | FLT3 | 1.32231045 |
| 31 | CSNK1G2 | 1.30426567 |
| 32 | TEC | 1.30220523 |
| 33 | PLK3 | 1.27981933 |
| 34 | TSSK6 | 1.27010717 |
| 35 | CSNK1A1L | 1.26003933 |
| 36 | PINK1 | 1.25933448 |
| 37 | CSNK1G1 | 1.20460753 |
| 38 | MYLK | 1.17809778 |
| 39 | INSRR | 1.16266817 |
| 40 | WNK3 | 1.15605899 |
| 41 | CSF1R | 1.13469943 |
| 42 | KDR | 1.05514868 |
| 43 | PBK | 1.01944465 |
| 44 | FRK | 1.01140944 |
| 45 | RPS6KA4 | 0.99720680 |
| 46 | OXSR1 | 0.96288630 |
| 47 | ERBB3 | 0.92280263 |
| 48 | PDK2 | 0.89485858 |
| 49 | DYRK2 | 0.88680072 |
| 50 | PLK2 | 0.88284874 |
| 51 | PHKG1 | 0.88230951 |
| 52 | PHKG2 | 0.88230951 |
| 53 | MKNK1 | 0.86460230 |
| 54 | RPS6KA5 | 0.84420383 |
| 55 | IKBKB | 0.75522285 |
| 56 | TRPM7 | 0.72685055 |
| 57 | EIF2AK2 | 0.70910789 |
| 58 | MATK | 0.70215724 |
| 59 | BCR | 0.67562629 |
| 60 | GRK5 | 0.67197448 |
| 61 | NEK1 | 0.65799103 |
| 62 | PRKCE | 0.63342215 |
| 63 | RIPK4 | 0.63155655 |
| 64 | ALK | 0.63019031 |
| 65 | PLK4 | 0.61612548 |
| 66 | ITK | 0.60673107 |
| 67 | MAPK13 | 0.57877255 |
| 68 | DAPK2 | 0.56824393 |
| 69 | CHUK | 0.56242713 |
| 70 | SYK | 0.53568835 |
| 71 | EIF2AK1 | 0.52978325 |
| 72 | DAPK3 | 0.50088143 |
| 73 | GRK6 | 0.49575182 |
| 74 | CSNK1A1 | 0.47645152 |
| 75 | PKN1 | 0.47406451 |
| 76 | MINK1 | 0.44416802 |
| 77 | IGF1R | 0.44120431 |
| 78 | PTK2B | 0.43544361 |
| 79 | LIMK1 | 0.42501906 |
| 80 | LCK | 0.41688038 |
| 81 | FER | 0.41149321 |
| 82 | LYN | 0.39725177 |
| 83 | SCYL2 | 0.39248162 |
| 84 | ILK | 0.39195921 |
| 85 | CAMK2D | 0.38489598 |
| 86 | CDC7 | 0.38235775 |
| 87 | CSNK2A1 | 0.38105973 |
| 88 | ADRBK1 | 0.36952522 |
| 89 | ATR | 0.36185156 |
| 90 | CDK9 | 0.35983429 |
| 91 | OBSCN | 0.33638260 |
| 92 | TAF1 | 0.33616869 |
| 93 | MKNK2 | 0.32351851 |
| 94 | MAP2K6 | 0.30564692 |
| 95 | PIK3CG | 0.29760486 |
| 96 | CAMK2A | 0.28233476 |
| 97 | BLK | 0.28225771 |
| 98 | AURKB | 0.28079811 |
| 99 | GRK7 | 0.27776407 |
| 100 | STK38L | 0.27120425 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.48660110 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.72706017 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.24901986 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.99428263 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.95925903 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.86694920 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.85393318 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.66700880 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.60973558 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.41125938 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.19532970 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.93148951 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.89178132 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.87751160 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.83892755 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.60290855 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.54730094 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.52153830 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.48399879 |
| 20 | Ribosome_Homo sapiens_hsa03010 | 1.47626687 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.43889827 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.42901897 |
| 23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.41665555 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34550262 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.34509167 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.33441293 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.29360517 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.27108909 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.25393558 |
| 30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.21355867 |
| 31 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.19095095 |
| 32 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.17206686 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 1.16456934 |
| 34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.13690327 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.13629963 |
| 36 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.12685158 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.12593245 |
| 38 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.07236231 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.01968534 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.00127563 |
| 41 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.98983146 |
| 42 | Spliceosome_Homo sapiens_hsa03040 | 0.98706309 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.97406174 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 0.96314969 |
| 45 | Basal transcription factors_Homo sapiens_hsa03022 | 0.95890875 |
| 46 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.94361421 |
| 47 | DNA replication_Homo sapiens_hsa03030 | 0.94058315 |
| 48 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.92686055 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.91125056 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.87947228 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.86975347 |
| 52 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86761494 |
| 53 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.85464410 |
| 54 | Leishmaniasis_Homo sapiens_hsa05140 | 0.82054436 |
| 55 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.81419104 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.80712885 |
| 57 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.77638982 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.77086114 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.76296431 |
| 60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.75992175 |
| 61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75779980 |
| 62 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.73150052 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71058733 |
| 64 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69390178 |
| 65 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.68072392 |
| 66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65894204 |
| 67 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.62042123 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61380007 |
| 69 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60286568 |
| 70 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.60112516 |
| 71 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.59238054 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.55586474 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54992353 |
| 74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53872910 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.53503505 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53030514 |
| 77 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.52899600 |
| 78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52350366 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.51768560 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50300892 |
| 81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48855768 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48536899 |
| 83 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.46429791 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46362691 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42900663 |
| 86 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.38700481 |
| 87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38612327 |
| 88 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.37999054 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35924101 |
| 90 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.35821408 |
| 91 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.34685445 |
| 92 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34516528 |
| 93 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34325332 |
| 94 | Phagosome_Homo sapiens_hsa04145 | 0.32409332 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32238572 |
| 96 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.32016498 |
| 97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.30325293 |
| 98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.28170072 |
| 99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.27826814 |
| 100 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.26648950 |

