

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ATP synthesis coupled proton transport (GO:0015986) | 5.37960403 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.37960403 |
| 3 | protein complex biogenesis (GO:0070271) | 5.33021463 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.29298419 |
| 5 | behavioral response to nicotine (GO:0035095) | 5.03732030 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.96772739 |
| 7 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.77475464 |
| 8 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.77475464 |
| 9 | NADH dehydrogenase complex assembly (GO:0010257) | 4.77475464 |
| 10 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.70276854 |
| 11 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.63090764 |
| 12 | ribosomal small subunit assembly (GO:0000028) | 4.52081707 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.41402592 |
| 14 | spliceosomal complex assembly (GO:0000245) | 4.22005384 |
| 15 | viral transcription (GO:0019083) | 4.00435662 |
| 16 | translational termination (GO:0006415) | 3.92632798 |
| 17 | protein K6-linked ubiquitination (GO:0085020) | 3.79955804 |
| 18 | epithelial cilium movement (GO:0003351) | 3.79500079 |
| 19 | respiratory electron transport chain (GO:0022904) | 3.74687062 |
| 20 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.72101578 |
| 21 | rRNA modification (GO:0000154) | 3.70319132 |
| 22 | electron transport chain (GO:0022900) | 3.67868624 |
| 23 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.61855654 |
| 24 | rRNA methylation (GO:0031167) | 3.60741264 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 3.58032042 |
| 26 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.53024511 |
| 27 | protein targeting to ER (GO:0045047) | 3.51094874 |
| 28 | spliceosomal snRNP assembly (GO:0000387) | 3.51062348 |
| 29 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.49865974 |
| 30 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.44687500 |
| 31 | translational elongation (GO:0006414) | 3.43141904 |
| 32 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.41295260 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.39113355 |
| 34 | protein localization to endoplasmic reticulum (GO:0070972) | 3.36628665 |
| 35 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.33467871 |
| 36 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.32721048 |
| 37 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.32721048 |
| 38 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.32721048 |
| 39 | sequestering of actin monomers (GO:0042989) | 3.31400556 |
| 40 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.31294265 |
| 41 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.30880848 |
| 42 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.29845280 |
| 43 | L-phenylalanine catabolic process (GO:0006559) | 3.29845280 |
| 44 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.27850590 |
| 45 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.27850590 |
| 46 | cytochrome complex assembly (GO:0017004) | 3.27013015 |
| 47 | GTP biosynthetic process (GO:0006183) | 3.26968381 |
| 48 | regulation of mitochondrial translation (GO:0070129) | 3.25274023 |
| 49 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.24467726 |
| 50 | negative regulation of ligase activity (GO:0051352) | 3.24467726 |
| 51 | aromatic amino acid family catabolic process (GO:0009074) | 3.21508056 |
| 52 | tryptophan metabolic process (GO:0006568) | 3.20643182 |
| 53 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.19698461 |
| 54 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.18175960 |
| 55 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.18175960 |
| 56 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.18158394 |
| 57 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.17792311 |
| 58 | ribosomal small subunit biogenesis (GO:0042274) | 3.14183964 |
| 59 | indole-containing compound catabolic process (GO:0042436) | 3.14097191 |
| 60 | indolalkylamine catabolic process (GO:0046218) | 3.14097191 |
| 61 | tryptophan catabolic process (GO:0006569) | 3.14097191 |
| 62 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.13541347 |
| 63 | platelet dense granule organization (GO:0060155) | 3.12390795 |
| 64 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.11988079 |
| 65 | chaperone-mediated protein transport (GO:0072321) | 3.11847466 |
| 66 | L-phenylalanine metabolic process (GO:0006558) | 3.08769210 |
| 67 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.08769210 |
| 68 | ATP biosynthetic process (GO:0006754) | 3.07257457 |
| 69 | left/right pattern formation (GO:0060972) | 3.03600019 |
| 70 | maturation of SSU-rRNA (GO:0030490) | 3.02345877 |
| 71 | hydrogen ion transmembrane transport (GO:1902600) | 3.01724178 |
| 72 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.01489164 |
| 73 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.01336271 |
| 74 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.01336271 |
| 75 | ribosomal large subunit biogenesis (GO:0042273) | 3.00574222 |
| 76 | viral life cycle (GO:0019058) | 2.99338487 |
| 77 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.99190567 |
| 78 | protein neddylation (GO:0045116) | 2.98837255 |
| 79 | mismatch repair (GO:0006298) | 2.98628043 |
| 80 | positive regulation of gastrulation (GO:2000543) | 2.95140214 |
| 81 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.94541255 |
| 82 | cellular protein complex disassembly (GO:0043624) | 2.92973237 |
| 83 | translation (GO:0006412) | 2.92305322 |
| 84 | cellular component biogenesis (GO:0044085) | 2.91692428 |
| 85 | indolalkylamine metabolic process (GO:0006586) | 2.90257537 |
| 86 | chromatin remodeling at centromere (GO:0031055) | 2.89390414 |
| 87 | intracellular protein transmembrane import (GO:0044743) | 2.89326284 |
| 88 | DNA strand elongation (GO:0022616) | 2.89010964 |
| 89 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.84522058 |
| 90 | viral mRNA export from host cell nucleus (GO:0046784) | 2.83859736 |
| 91 | spindle assembly involved in mitosis (GO:0090307) | 2.80318190 |
| 92 | UTP biosynthetic process (GO:0006228) | 2.78695594 |
| 93 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.77309303 |
| 94 | termination of RNA polymerase III transcription (GO:0006386) | 2.77309303 |
| 95 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.76836111 |
| 96 | translational initiation (GO:0006413) | 2.73798419 |
| 97 | CENP-A containing nucleosome assembly (GO:0034080) | 2.73520992 |
| 98 | oxidative phosphorylation (GO:0006119) | 2.71643363 |
| 99 | protein-cofactor linkage (GO:0018065) | 2.71131078 |
| 100 | proton transport (GO:0015992) | 2.70776573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.78483344 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.26068937 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.89292063 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.70727667 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.28927865 |
| 6 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.27248790 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.94980969 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.74718967 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.68166363 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.66088203 |
| 11 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.56099811 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.48780084 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.44589646 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.33214844 |
| 15 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.26956633 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.20413063 |
| 17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.20406792 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.18433926 |
| 19 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.09175554 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.09013396 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04730525 |
| 22 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.93564919 |
| 23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.86486745 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.86093945 |
| 25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.77522289 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72840198 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.71018388 |
| 28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.68903366 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.68297189 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.67978410 |
| 31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.64830621 |
| 32 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.63358077 |
| 33 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.59721398 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58559583 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.57433200 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55272510 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.53553704 |
| 38 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.47050974 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.47019440 |
| 40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.46844809 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.45825004 |
| 42 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45078418 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42248117 |
| 44 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.41331203 |
| 45 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.40703308 |
| 46 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.39351157 |
| 47 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.39351157 |
| 48 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.38360935 |
| 49 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.38360935 |
| 50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33570715 |
| 51 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.32893376 |
| 52 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.31836259 |
| 53 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.27545988 |
| 54 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.27041544 |
| 55 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.26925809 |
| 56 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.23307552 |
| 57 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.22529958 |
| 58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.22124621 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.21633974 |
| 60 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.17379758 |
| 61 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.17348377 |
| 62 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.16108570 |
| 63 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.15529269 |
| 64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14294472 |
| 65 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.12883326 |
| 66 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11597599 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.09773950 |
| 68 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08906977 |
| 69 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07799966 |
| 70 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.07721241 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.07172842 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06268638 |
| 73 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05569291 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05547114 |
| 75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.04677206 |
| 76 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04630020 |
| 77 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04096150 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03130493 |
| 79 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.02884898 |
| 80 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.02844176 |
| 81 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.01839111 |
| 82 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.01135944 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00956059 |
| 84 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.00584790 |
| 85 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99965838 |
| 86 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99878767 |
| 87 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.97615005 |
| 88 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96314404 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94558369 |
| 90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.93988734 |
| 91 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.92845825 |
| 92 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.92547208 |
| 93 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91290986 |
| 94 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.91247775 |
| 95 | ERA_21632823_ChIP-Seq_H3396_Human | 0.90472786 |
| 96 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.89242463 |
| 97 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88475466 |
| 98 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.86849967 |
| 99 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.86447196 |
| 100 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.86177586 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002837_dystrophic_cardiac_calcinosis | 4.69732981 |
| 2 | MP0001986_abnormal_taste_sensitivity | 4.59764644 |
| 3 | MP0005083_abnormal_biliary_tract | 3.96480000 |
| 4 | MP0005084_abnormal_gallbladder_morpholo | 3.77333131 |
| 5 | MP0004145_abnormal_muscle_electrophysio | 3.76743874 |
| 6 | MP0002653_abnormal_ependyma_morphology | 3.33797212 |
| 7 | MP0006292_abnormal_olfactory_placode | 3.23717415 |
| 8 | MP0005365_abnormal_bile_salt | 3.14444410 |
| 9 | MP0009379_abnormal_foot_pigmentation | 3.04349448 |
| 10 | MP0002138_abnormal_hepatobiliary_system | 2.60464197 |
| 11 | MP0003283_abnormal_digestive_organ | 2.42475182 |
| 12 | MP0002938_white_spotting | 2.26814638 |
| 13 | MP0003123_paternal_imprinting | 2.25757904 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.18609182 |
| 15 | MP0002234_abnormal_pharynx_morphology | 2.13407711 |
| 16 | MP0005075_abnormal_melanosome_morpholog | 2.06873427 |
| 17 | MP0008789_abnormal_olfactory_epithelium | 2.00675933 |
| 18 | MP0005408_hypopigmentation | 1.96504503 |
| 19 | MP0006072_abnormal_retinal_apoptosis | 1.91883110 |
| 20 | MP0002163_abnormal_gland_morphology | 1.84343734 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.79529050 |
| 22 | MP0001485_abnormal_pinna_reflex | 1.76615685 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.69868110 |
| 24 | MP0002277_abnormal_respiratory_mucosa | 1.67918324 |
| 25 | MP0002638_abnormal_pupillary_reflex | 1.64332731 |
| 26 | MP0008995_early_reproductive_senescence | 1.59112888 |
| 27 | MP0003718_maternal_effect | 1.52779546 |
| 28 | MP0003880_abnormal_central_pattern | 1.48943195 |
| 29 | MP0005085_abnormal_gallbladder_physiolo | 1.46619498 |
| 30 | MP0001293_anophthalmia | 1.39637667 |
| 31 | MP0005394_taste/olfaction_phenotype | 1.38838377 |
| 32 | MP0005499_abnormal_olfactory_system | 1.38838377 |
| 33 | MP0003119_abnormal_digestive_system | 1.31911389 |
| 34 | MP0008875_abnormal_xenobiotic_pharmacok | 1.31088096 |
| 35 | MP0003121_genomic_imprinting | 1.30431017 |
| 36 | MP0005379_endocrine/exocrine_gland_phen | 1.28995800 |
| 37 | MP0008872_abnormal_physiological_respon | 1.26727276 |
| 38 | MP0002928_abnormal_bile_duct | 1.22897237 |
| 39 | MP0001666_abnormal_nutrient_absorption | 1.20867737 |
| 40 | MP0001984_abnormal_olfaction | 1.18322618 |
| 41 | MP0005253_abnormal_eye_physiology | 1.18293282 |
| 42 | MP0003315_abnormal_perineum_morphology | 1.17580259 |
| 43 | MP0005389_reproductive_system_phenotype | 1.17509701 |
| 44 | MP0005646_abnormal_pituitary_gland | 1.14584941 |
| 45 | MP0002160_abnormal_reproductive_system | 1.14484979 |
| 46 | MP0008007_abnormal_cellular_replicative | 1.09360470 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.09074432 |
| 48 | MP0008877_abnormal_DNA_methylation | 1.07250971 |
| 49 | MP0003195_calcinosis | 1.05913653 |
| 50 | MP0001905_abnormal_dopamine_level | 1.04867826 |
| 51 | MP0001529_abnormal_vocalization | 1.04710394 |
| 52 | MP0010094_abnormal_chromosome_stability | 1.04694100 |
| 53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.04645271 |
| 54 | MP0000049_abnormal_middle_ear | 1.03523366 |
| 55 | MP0003646_muscle_fatigue | 1.03198659 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 1.01373901 |
| 57 | MP0004957_abnormal_blastocyst_morpholog | 1.01016241 |
| 58 | MP0003786_premature_aging | 1.00740483 |
| 59 | MP0003878_abnormal_ear_physiology | 0.96943217 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 0.96943217 |
| 61 | MP0000383_abnormal_hair_follicle | 0.93421809 |
| 62 | MP0002102_abnormal_ear_morphology | 0.91904125 |
| 63 | MP0001764_abnormal_homeostasis | 0.90904019 |
| 64 | MP0002272_abnormal_nervous_system | 0.89612609 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 0.88540909 |
| 66 | MP0002751_abnormal_autonomic_nervous | 0.87829641 |
| 67 | MP0001919_abnormal_reproductive_system | 0.84849119 |
| 68 | MP0002006_tumorigenesis | 0.84441362 |
| 69 | MP0000566_synostosis | 0.84227097 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.83823073 |
| 71 | MP0002282_abnormal_trachea_morphology | 0.83360033 |
| 72 | MP0003943_abnormal_hepatobiliary_system | 0.83064581 |
| 73 | MP0004215_abnormal_myocardial_fiber | 0.81108714 |
| 74 | MP0000613_abnormal_salivary_gland | 0.80467845 |
| 75 | MP0010386_abnormal_urinary_bladder | 0.79794685 |
| 76 | MP0001968_abnormal_touch/_nociception | 0.77586348 |
| 77 | MP0005332_abnormal_amino_acid | 0.76952208 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.76214685 |
| 79 | MP0001502_abnormal_circadian_rhythm | 0.75228288 |
| 80 | MP0008775_abnormal_heart_ventricle | 0.74465391 |
| 81 | MP0003011_delayed_dark_adaptation | 0.74196837 |
| 82 | MP0002210_abnormal_sex_determination | 0.73024895 |
| 83 | MP0002557_abnormal_social/conspecific_i | 0.72904835 |
| 84 | MP0002693_abnormal_pancreas_physiology | 0.72083830 |
| 85 | MP0003186_abnormal_redox_activity | 0.71642202 |
| 86 | MP0002095_abnormal_skin_pigmentation | 0.71338797 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.71173828 |
| 88 | MP0004742_abnormal_vestibular_system | 0.69090770 |
| 89 | MP0003122_maternal_imprinting | 0.68923465 |
| 90 | MP0005195_abnormal_posterior_eye | 0.66058135 |
| 91 | MP0005391_vision/eye_phenotype | 0.65897842 |
| 92 | MP0005220_abnormal_exocrine_pancreas | 0.64690332 |
| 93 | MP0002295_abnormal_pulmonary_circulatio | 0.62259307 |
| 94 | MP0003936_abnormal_reproductive_system | 0.61568954 |
| 95 | MP0001286_abnormal_eye_development | 0.61393090 |
| 96 | MP0002064_seizures | 0.60574911 |
| 97 | MP0000026_abnormal_inner_ear | 0.60543595 |
| 98 | MP0002233_abnormal_nose_morphology | 0.59456898 |
| 99 | MP0009046_muscle_twitch | 0.58010190 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.57699283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.95150678 |
| 2 | Acute encephalopathy (HP:0006846) | 4.57990719 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.39425507 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.06978151 |
| 5 | Type II lissencephaly (HP:0007260) | 4.03141826 |
| 6 | 3-Methylglutaconic aciduria (HP:0003535) | 3.96462088 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.89994262 |
| 8 | Cerebral edema (HP:0002181) | 3.56770700 |
| 9 | Increased CSF lactate (HP:0002490) | 3.52648722 |
| 10 | Retinal dysplasia (HP:0007973) | 3.49999033 |
| 11 | Reticulocytopenia (HP:0001896) | 3.25408786 |
| 12 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.23203019 |
| 13 | Abolished electroretinogram (ERG) (HP:0000550) | 3.16678099 |
| 14 | Nephronophthisis (HP:0000090) | 3.10395997 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.10363500 |
| 16 | Pancreatic fibrosis (HP:0100732) | 3.08999350 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 3.05455498 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.05455498 |
| 19 | Degeneration of anterior horn cells (HP:0002398) | 2.94493441 |
| 20 | Abnormality of the anterior horn cell (HP:0006802) | 2.94493441 |
| 21 | Aplastic anemia (HP:0001915) | 2.94170634 |
| 22 | Medial flaring of the eyebrow (HP:0010747) | 2.90826822 |
| 23 | Hepatic necrosis (HP:0002605) | 2.90696687 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 2.76857762 |
| 25 | Pancreatic cysts (HP:0001737) | 2.67857962 |
| 26 | Increased hepatocellular lipid droplets (HP:0006565) | 2.60508544 |
| 27 | True hermaphroditism (HP:0010459) | 2.58762567 |
| 28 | Duplicated collecting system (HP:0000081) | 2.56663101 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.55562934 |
| 30 | Abnormality of the renal collecting system (HP:0004742) | 2.52908855 |
| 31 | Optic disc pallor (HP:0000543) | 2.49637437 |
| 32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.36795450 |
| 33 | Redundant skin (HP:0001582) | 2.36794442 |
| 34 | Abnormality of the renal medulla (HP:0100957) | 2.34983027 |
| 35 | Tubulointerstitial nephritis (HP:0001970) | 2.33322428 |
| 36 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.31479365 |
| 37 | Respiratory failure (HP:0002878) | 2.31354703 |
| 38 | Gonadotropin excess (HP:0000837) | 2.31240589 |
| 39 | Anophthalmia (HP:0000528) | 2.30473633 |
| 40 | Broad distal phalanx of finger (HP:0009836) | 2.26892202 |
| 41 | Hypothermia (HP:0002045) | 2.24673742 |
| 42 | Multiple enchondromatosis (HP:0005701) | 2.24272834 |
| 43 | Increased serum lactate (HP:0002151) | 2.22003917 |
| 44 | Hypoplastic pelvis (HP:0008839) | 2.18671485 |
| 45 | Abnormality of the preputium (HP:0100587) | 2.18428270 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.17913149 |
| 47 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.16085022 |
| 48 | Small hand (HP:0200055) | 2.14531349 |
| 49 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.10355333 |
| 50 | Meckel diverticulum (HP:0002245) | 2.07377499 |
| 51 | Maternal diabetes (HP:0009800) | 2.07040515 |
| 52 | Lactic acidosis (HP:0003128) | 2.06774652 |
| 53 | Clubbing of toes (HP:0100760) | 2.04381063 |
| 54 | Absent thumb (HP:0009777) | 2.04310382 |
| 55 | Intrahepatic cholestasis (HP:0001406) | 2.03707864 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.03392558 |
| 57 | Lethargy (HP:0001254) | 2.03226136 |
| 58 | Renal Fanconi syndrome (HP:0001994) | 2.03171089 |
| 59 | Leukodystrophy (HP:0002415) | 2.02352959 |
| 60 | Exercise intolerance (HP:0003546) | 1.99177728 |
| 61 | Anterior segment dysgenesis (HP:0007700) | 1.98276760 |
| 62 | Type I transferrin isoform profile (HP:0003642) | 1.94385981 |
| 63 | Optic nerve hypoplasia (HP:0000609) | 1.93402466 |
| 64 | X-linked dominant inheritance (HP:0001423) | 1.93001956 |
| 65 | Prostate neoplasm (HP:0100787) | 1.91964953 |
| 66 | Cystic liver disease (HP:0006706) | 1.91743118 |
| 67 | Horseshoe kidney (HP:0000085) | 1.91086970 |
| 68 | Sclerocornea (HP:0000647) | 1.90594851 |
| 69 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.90582193 |
| 70 | Tongue fasciculations (HP:0001308) | 1.89970951 |
| 71 | Cleft eyelid (HP:0000625) | 1.89546813 |
| 72 | Lissencephaly (HP:0001339) | 1.87158214 |
| 73 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.84420342 |
| 74 | Colon cancer (HP:0003003) | 1.82815154 |
| 75 | Delayed CNS myelination (HP:0002188) | 1.82439842 |
| 76 | Abnormality of the ileum (HP:0001549) | 1.82151813 |
| 77 | Chromsome breakage (HP:0040012) | 1.81985687 |
| 78 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.80722355 |
| 79 | Gait imbalance (HP:0002141) | 1.80426272 |
| 80 | Abnormal protein glycosylation (HP:0012346) | 1.77337685 |
| 81 | Abnormal glycosylation (HP:0012345) | 1.77337685 |
| 82 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.77337685 |
| 83 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.77337685 |
| 84 | Bifid tongue (HP:0010297) | 1.77230364 |
| 85 | Congenital primary aphakia (HP:0007707) | 1.74790540 |
| 86 | Postaxial foot polydactyly (HP:0001830) | 1.73035427 |
| 87 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.70222020 |
| 88 | Pendular nystagmus (HP:0012043) | 1.69929923 |
| 89 | Panhypogammaglobulinemia (HP:0003139) | 1.68613989 |
| 90 | Macrocytic anemia (HP:0001972) | 1.67988314 |
| 91 | Methylmalonic acidemia (HP:0002912) | 1.66357240 |
| 92 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.65075134 |
| 93 | Septo-optic dysplasia (HP:0100842) | 1.64336143 |
| 94 | Duodenal stenosis (HP:0100867) | 1.64237783 |
| 95 | Small intestinal stenosis (HP:0012848) | 1.64237783 |
| 96 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.63966747 |
| 97 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.63966747 |
| 98 | Blindness (HP:0000618) | 1.63423685 |
| 99 | Postaxial hand polydactyly (HP:0001162) | 1.63368516 |
| 100 | Median cleft lip (HP:0000161) | 1.62800991 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR1B | 5.04805155 |
| 2 | VRK2 | 4.14094757 |
| 3 | TIE1 | 3.54628899 |
| 4 | EIF2AK1 | 3.50074651 |
| 5 | STK16 | 2.66813980 |
| 6 | CDK8 | 2.62483518 |
| 7 | TLK1 | 2.59834360 |
| 8 | BUB1 | 2.49906850 |
| 9 | VRK1 | 2.48605755 |
| 10 | ZAK | 2.42422127 |
| 11 | TGFBR1 | 2.40540813 |
| 12 | EIF2AK3 | 2.23155064 |
| 13 | PASK | 2.22721184 |
| 14 | BCKDK | 2.21832799 |
| 15 | NUAK1 | 1.95414105 |
| 16 | GRK1 | 1.93465361 |
| 17 | TSSK6 | 1.88963537 |
| 18 | PLK4 | 1.81806945 |
| 19 | NME1 | 1.81361028 |
| 20 | PDK2 | 1.70170572 |
| 21 | STK24 | 1.53655460 |
| 22 | MKNK2 | 1.47927944 |
| 23 | TAOK3 | 1.40437475 |
| 24 | PLK3 | 1.34163573 |
| 25 | ADRBK2 | 1.25752767 |
| 26 | SRPK1 | 1.24519071 |
| 27 | WNK3 | 1.23739394 |
| 28 | ALK | 1.18630417 |
| 29 | MAP3K9 | 1.18477294 |
| 30 | MAPKAPK3 | 1.18238915 |
| 31 | MKNK1 | 1.10481355 |
| 32 | NME2 | 1.06516844 |
| 33 | ABL2 | 1.04648424 |
| 34 | TEC | 1.04121195 |
| 35 | EPHB2 | 1.03618212 |
| 36 | PRKD3 | 1.02020853 |
| 37 | INSRR | 0.98566348 |
| 38 | CDC7 | 0.94374606 |
| 39 | CSNK1G3 | 0.94125674 |
| 40 | PHKG2 | 0.93263266 |
| 41 | PHKG1 | 0.93263266 |
| 42 | FRK | 0.91659334 |
| 43 | MST4 | 0.91364273 |
| 44 | CSNK1G1 | 0.90460111 |
| 45 | GRK7 | 0.89740190 |
| 46 | CDK9 | 0.81823654 |
| 47 | DYRK2 | 0.79308717 |
| 48 | CASK | 0.76714048 |
| 49 | EIF2AK2 | 0.76597635 |
| 50 | MAP4K2 | 0.68929957 |
| 51 | CSNK1G2 | 0.67966969 |
| 52 | CHEK2 | 0.67623483 |
| 53 | PLK2 | 0.67380045 |
| 54 | CSNK1A1L | 0.66347656 |
| 55 | DAPK1 | 0.66041000 |
| 56 | TTK | 0.64875237 |
| 57 | ATR | 0.63864812 |
| 58 | MATK | 0.63438805 |
| 59 | CHUK | 0.59692572 |
| 60 | ADRBK1 | 0.59018409 |
| 61 | CSNK1A1 | 0.58414156 |
| 62 | TAF1 | 0.57565345 |
| 63 | CAMKK2 | 0.57110568 |
| 64 | STK3 | 0.55893083 |
| 65 | BLK | 0.54165477 |
| 66 | IKBKB | 0.53211158 |
| 67 | STK38L | 0.51643945 |
| 68 | RPS6KA4 | 0.49480909 |
| 69 | NEK2 | 0.48077745 |
| 70 | MAPK13 | 0.47044245 |
| 71 | IRAK1 | 0.45387368 |
| 72 | FES | 0.44965161 |
| 73 | AURKB | 0.44599691 |
| 74 | KDR | 0.44519378 |
| 75 | DAPK3 | 0.44383113 |
| 76 | PRKCG | 0.43012276 |
| 77 | CSNK2A2 | 0.42220539 |
| 78 | CSNK2A1 | 0.41951760 |
| 79 | PTK2B | 0.40099503 |
| 80 | PLK1 | 0.39377319 |
| 81 | LMTK2 | 0.38381324 |
| 82 | PRKCQ | 0.37944320 |
| 83 | OXSR1 | 0.37530198 |
| 84 | OBSCN | 0.35230299 |
| 85 | MAP2K7 | 0.34313239 |
| 86 | PRKCD | 0.33226269 |
| 87 | PRKACA | 0.31650896 |
| 88 | IRAK4 | 0.31135346 |
| 89 | PKN1 | 0.30146768 |
| 90 | TXK | 0.29792930 |
| 91 | AURKA | 0.29578460 |
| 92 | PRKCE | 0.28997223 |
| 93 | NLK | 0.25666680 |
| 94 | GRK5 | 0.23499089 |
| 95 | MARK1 | 0.23463179 |
| 96 | NEK9 | 0.22519758 |
| 97 | CSNK1E | 0.22463661 |
| 98 | LIMK1 | 0.22224760 |
| 99 | MAP3K4 | 0.22072206 |
| 100 | ATM | 0.20634310 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.70096723 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.14496186 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.07714124 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.95748653 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.44591598 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.61048871 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.33213906 |
| 8 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.21681222 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.15072307 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.10134728 |
| 11 | Protein export_Homo sapiens_hsa03060 | 1.72720605 |
| 12 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.71694440 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.67505890 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.67212509 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.66280480 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.63297437 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.63288980 |
| 18 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.61135103 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.56797876 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.56456391 |
| 21 | Base excision repair_Homo sapiens_hsa03410 | 1.47639126 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.44788321 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.42967391 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.42101625 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.41037421 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.29721950 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.28780980 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.26848138 |
| 29 | Purine metabolism_Homo sapiens_hsa00230 | 1.21321772 |
| 30 | RNA transport_Homo sapiens_hsa03013 | 1.20159825 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.18334368 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.16338200 |
| 33 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16082605 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.12354379 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.10381162 |
| 36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.06362972 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.05250245 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04194640 |
| 39 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.99819979 |
| 40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.97086799 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 0.96124018 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94354484 |
| 43 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.93698323 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91192159 |
| 45 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.90155900 |
| 46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.87049813 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84108084 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80346125 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.79974553 |
| 50 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.78742984 |
| 51 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.78283883 |
| 52 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.76168613 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75578286 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.75352703 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.74637946 |
| 56 | Nicotine addiction_Homo sapiens_hsa05033 | 0.74055654 |
| 57 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71266411 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.70750335 |
| 59 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.70196727 |
| 60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68757039 |
| 61 | Sulfur relay system_Homo sapiens_hsa04122 | 0.68574372 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66689691 |
| 63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64587634 |
| 64 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.63505481 |
| 65 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.61514264 |
| 66 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.61393115 |
| 67 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60845721 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.58741864 |
| 69 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.57820736 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55617483 |
| 71 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.53851484 |
| 72 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.53757369 |
| 73 | Insulin secretion_Homo sapiens_hsa04911 | 0.53196357 |
| 74 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53153533 |
| 75 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.52928324 |
| 76 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.49626498 |
| 77 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.47143510 |
| 78 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44347894 |
| 79 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43806112 |
| 80 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.43776060 |
| 81 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43372111 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.43138868 |
| 83 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.42968511 |
| 84 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42574107 |
| 85 | Carbon metabolism_Homo sapiens_hsa01200 | 0.41294728 |
| 86 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.41290075 |
| 87 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.39781229 |
| 88 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.39713457 |
| 89 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.39623820 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38000837 |
| 91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37589664 |
| 92 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.37015065 |
| 93 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.32539885 |
| 94 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.29221458 |
| 95 | Allograft rejection_Homo sapiens_hsa05330 | 0.27601343 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.26654722 |
| 97 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.26242659 |
| 98 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.25574989 |
| 99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.23553824 |
| 100 | Asthma_Homo sapiens_hsa05310 | 0.23025822 |

