

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein complex biogenesis (GO:0070271) | 5.66146063 |
| 2 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.53730033 |
| 3 | NADH dehydrogenase complex assembly (GO:0010257) | 5.53730033 |
| 4 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.53730033 |
| 5 | GMP metabolic process (GO:0046037) | 5.38707855 |
| 6 | mitochondrial respiratory chain complex assembly (GO:0033108) | 5.27311842 |
| 7 | behavioral response to nicotine (GO:0035095) | 5.23617498 |
| 8 | cullin deneddylation (GO:0010388) | 4.99370560 |
| 9 | respiratory chain complex IV assembly (GO:0008535) | 4.78624102 |
| 10 | cytochrome complex assembly (GO:0017004) | 4.59224265 |
| 11 | protein neddylation (GO:0045116) | 4.48703121 |
| 12 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 4.39900531 |
| 13 | interferon-gamma production (GO:0032609) | 4.37361959 |
| 14 | positive regulation of T cell cytokine production (GO:0002726) | 4.19313904 |
| 15 | protein deneddylation (GO:0000338) | 4.18003270 |
| 16 | positive regulation of T cell chemotaxis (GO:0010820) | 4.12061033 |
| 17 | regulation of T cell chemotaxis (GO:0010819) | 4.12061033 |
| 18 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.90906061 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 3.90906061 |
| 20 | purine nucleobase biosynthetic process (GO:0009113) | 3.86460855 |
| 21 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.81838822 |
| 22 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.80964086 |
| 23 | negative regulation of T cell mediated immunity (GO:0002710) | 3.77462713 |
| 24 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.76334975 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.75412141 |
| 26 | IMP biosynthetic process (GO:0006188) | 3.66103035 |
| 27 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.65523364 |
| 28 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.63562673 |
| 29 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.63481510 |
| 30 | adenosine metabolic process (GO:0046085) | 3.60873171 |
| 31 | DNA deamination (GO:0045006) | 3.60844771 |
| 32 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.57174893 |
| 33 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.54722121 |
| 34 | Peyers patch development (GO:0048541) | 3.54722121 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.48501408 |
| 36 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.41447636 |
| 37 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.41253186 |
| 38 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.38850618 |
| 39 | lymphocyte chemotaxis (GO:0048247) | 3.22586403 |
| 40 | proteasome assembly (GO:0043248) | 3.17650467 |
| 41 | positive regulation of protein homodimerization activity (GO:0090073) | 3.16432976 |
| 42 | nucleobase biosynthetic process (GO:0046112) | 3.09283438 |
| 43 | sequestering of actin monomers (GO:0042989) | 3.05449270 |
| 44 | vitamin biosynthetic process (GO:0009110) | 3.04156641 |
| 45 | RNA destabilization (GO:0050779) | 3.03177836 |
| 46 | axonemal dynein complex assembly (GO:0070286) | 3.03128793 |
| 47 | protein K6-linked ubiquitination (GO:0085020) | 3.01825610 |
| 48 | regulation of gamma-delta T cell activation (GO:0046643) | 3.01335915 |
| 49 | positive regulation of release of sequestered calcium ion into cytosol (GO:0051281) | 2.98086810 |
| 50 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.97091169 |
| 51 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.96256498 |
| 52 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.95986606 |
| 53 | DNA damage response, detection of DNA damage (GO:0042769) | 2.95565417 |
| 54 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.94581661 |
| 55 | intra-S DNA damage checkpoint (GO:0031573) | 2.92086167 |
| 56 | viral mRNA export from host cell nucleus (GO:0046784) | 2.91055402 |
| 57 | negative regulation of telomere maintenance (GO:0032205) | 2.90461473 |
| 58 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.89757752 |
| 59 | aspartate family amino acid catabolic process (GO:0009068) | 2.89298238 |
| 60 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.84433014 |
| 61 | purine nucleotide salvage (GO:0032261) | 2.84005848 |
| 62 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.82299735 |
| 63 | IMP metabolic process (GO:0046040) | 2.80494552 |
| 64 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.78921328 |
| 65 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.78215475 |
| 66 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.78215475 |
| 67 | axoneme assembly (GO:0035082) | 2.77309670 |
| 68 | regulation of T cell cytokine production (GO:0002724) | 2.75749161 |
| 69 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.75448896 |
| 70 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.72460921 |
| 71 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.66865646 |
| 72 | negative regulation of T cell apoptotic process (GO:0070233) | 2.64990025 |
| 73 | regulation of DNA endoreduplication (GO:0032875) | 2.63332926 |
| 74 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.63272829 |
| 75 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.63272829 |
| 76 | electron transport chain (GO:0022900) | 2.63184151 |
| 77 | epithelial cilium movement (GO:0003351) | 2.63101519 |
| 78 | rhodopsin mediated signaling pathway (GO:0016056) | 2.62814296 |
| 79 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.62798303 |
| 80 | regulation of T-helper 1 type immune response (GO:0002825) | 2.62025682 |
| 81 | respiratory electron transport chain (GO:0022904) | 2.60334198 |
| 82 | ubiquinone metabolic process (GO:0006743) | 2.60306605 |
| 83 | purine-containing compound salvage (GO:0043101) | 2.59422919 |
| 84 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.56996633 |
| 85 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.56974988 |
| 86 | positive regulation of transforming growth factor beta production (GO:0071636) | 2.56921271 |
| 87 | tolerance induction (GO:0002507) | 2.56192243 |
| 88 | ncRNA catabolic process (GO:0034661) | 2.56164089 |
| 89 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.55929804 |
| 90 | regulation of mitochondrial translation (GO:0070129) | 2.53915764 |
| 91 | DNA catabolic process (GO:0006308) | 2.53529693 |
| 92 | head development (GO:0060322) | 2.53365479 |
| 93 | DNA catabolic process, endonucleolytic (GO:0000737) | 2.53359133 |
| 94 | negative regulation of heart rate (GO:0010459) | 2.53061936 |
| 95 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.52791088 |
| 96 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.52791088 |
| 97 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.52791088 |
| 98 | GPI anchor metabolic process (GO:0006505) | 2.52470984 |
| 99 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.51618488 |
| 100 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.51519544 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.06100027 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.26721929 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.89792346 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.84152061 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.73703971 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.52167446 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01736146 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.84808266 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.60110149 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.55770289 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45296274 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.41320355 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.38265543 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26779107 |
| 15 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.19831696 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.19274727 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.19199791 |
| 18 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.18753912 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.11410176 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.08384377 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07490155 |
| 22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.03530083 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.96861027 |
| 24 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.88486196 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.85425129 |
| 26 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79879260 |
| 27 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.77110388 |
| 28 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.77017922 |
| 29 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.69691588 |
| 30 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.65334988 |
| 31 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.59331657 |
| 32 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.58255683 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.56898342 |
| 34 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56527122 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.56520915 |
| 36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.51910845 |
| 37 | EWS_26573619_Chip-Seq_HEK293_Human | 1.43670557 |
| 38 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.41977430 |
| 39 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.40954299 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.40198853 |
| 41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39343036 |
| 42 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.38044814 |
| 43 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33881767 |
| 44 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.33797982 |
| 45 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.32725073 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30643908 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.29995009 |
| 48 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.27890690 |
| 49 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.26739168 |
| 50 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.24625427 |
| 51 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.24258432 |
| 52 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.21164958 |
| 53 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19544757 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19544757 |
| 55 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.17819985 |
| 56 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.17680053 |
| 57 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.17680053 |
| 58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.17388273 |
| 59 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.16175710 |
| 60 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15150436 |
| 61 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.13787715 |
| 62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11926437 |
| 63 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.11617894 |
| 64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11499715 |
| 65 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.09637422 |
| 66 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09315648 |
| 67 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09315648 |
| 68 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.08462593 |
| 69 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.06072368 |
| 70 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04648780 |
| 71 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03937080 |
| 72 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.03897763 |
| 73 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03333306 |
| 74 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.02753835 |
| 75 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.02228333 |
| 76 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.01199046 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00177948 |
| 78 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.99894642 |
| 79 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.98333776 |
| 80 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97474635 |
| 81 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.97250674 |
| 82 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.96825269 |
| 83 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.96628962 |
| 84 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.95573772 |
| 85 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.95560449 |
| 86 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.94725689 |
| 87 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93728293 |
| 88 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.93209676 |
| 89 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.92224060 |
| 90 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92074973 |
| 91 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91898502 |
| 92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.90910379 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.89914285 |
| 94 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.89161382 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88129092 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88129092 |
| 97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87785119 |
| 98 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.86967335 |
| 99 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86102484 |
| 100 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.85699913 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002822_catalepsy | 3.58863371 |
| 2 | MP0009697_abnormal_copulation | 3.08976152 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.02028953 |
| 4 | MP0005646_abnormal_pituitary_gland | 3.01757727 |
| 5 | MP0005085_abnormal_gallbladder_physiolo | 2.58576085 |
| 6 | MP0008007_abnormal_cellular_replicative | 2.44628803 |
| 7 | MP0001529_abnormal_vocalization | 2.41749351 |
| 8 | MP0004885_abnormal_endolymph | 2.37726697 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.15182528 |
| 10 | MP0005167_abnormal_blood-brain_barrier | 2.14683036 |
| 11 | MP0003011_delayed_dark_adaptation | 2.08402379 |
| 12 | MP0008004_abnormal_stomach_pH | 2.07184845 |
| 13 | MP0008775_abnormal_heart_ventricle | 2.05569572 |
| 14 | MP0004084_abnormal_cardiac_muscle | 2.05022796 |
| 15 | MP0003786_premature_aging | 2.04472208 |
| 16 | MP0008872_abnormal_physiological_respon | 1.95442443 |
| 17 | MP0001919_abnormal_reproductive_system | 1.95019944 |
| 18 | MP0003186_abnormal_redox_activity | 1.88703875 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.87398087 |
| 20 | MP0005408_hypopigmentation | 1.85143075 |
| 21 | MP0006035_abnormal_mitochondrial_morpho | 1.84569171 |
| 22 | MP0003646_muscle_fatigue | 1.84346008 |
| 23 | MP0002837_dystrophic_cardiac_calcinosis | 1.81476872 |
| 24 | MP0005075_abnormal_melanosome_morpholog | 1.80664933 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.70689484 |
| 26 | MP0003252_abnormal_bile_duct | 1.64974767 |
| 27 | MP0008789_abnormal_olfactory_epithelium | 1.64137775 |
| 28 | MP0002102_abnormal_ear_morphology | 1.63615787 |
| 29 | MP0001293_anophthalmia | 1.62404130 |
| 30 | MP0008877_abnormal_DNA_methylation | 1.61507621 |
| 31 | MP0005310_abnormal_salivary_gland | 1.60308204 |
| 32 | MP0002139_abnormal_hepatobiliary_system | 1.53359390 |
| 33 | MP0004142_abnormal_muscle_tone | 1.50704928 |
| 34 | MP0003195_calcinosis | 1.49626184 |
| 35 | MP0001485_abnormal_pinna_reflex | 1.41045700 |
| 36 | MP0003806_abnormal_nucleotide_metabolis | 1.37625581 |
| 37 | MP0001984_abnormal_olfaction | 1.37602082 |
| 38 | MP0005389_reproductive_system_phenotype | 1.36477563 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.34775741 |
| 40 | MP0004782_abnormal_surfactant_physiolog | 1.33177191 |
| 41 | MP0005671_abnormal_response_to | 1.32362724 |
| 42 | MP0002090_abnormal_vision | 1.31187073 |
| 43 | MP0002006_tumorigenesis | 1.30431404 |
| 44 | MP0005174_abnormal_tail_pigmentation | 1.29053293 |
| 45 | MP0002396_abnormal_hematopoietic_system | 1.24670078 |
| 46 | MP0001486_abnormal_startle_reflex | 1.22319654 |
| 47 | MP0004145_abnormal_muscle_electrophysio | 1.22087258 |
| 48 | MP0006276_abnormal_autonomic_nervous | 1.22032912 |
| 49 | MP0003718_maternal_effect | 1.20687570 |
| 50 | MP0002653_abnormal_ependyma_morphology | 1.20681180 |
| 51 | MP0008875_abnormal_xenobiotic_pharmacok | 1.20467338 |
| 52 | MP0001501_abnormal_sleep_pattern | 1.17029288 |
| 53 | MP0003111_abnormal_nucleus_morphology | 1.16569925 |
| 54 | MP0001440_abnormal_grooming_behavior | 1.15845777 |
| 55 | MP0009745_abnormal_behavioral_response | 1.13792680 |
| 56 | MP0000566_synostosis | 1.11973653 |
| 57 | MP0003763_abnormal_thymus_physiology | 1.11355729 |
| 58 | MP0002736_abnormal_nociception_after | 1.10916865 |
| 59 | MP0000613_abnormal_salivary_gland | 1.09546086 |
| 60 | MP0005394_taste/olfaction_phenotype | 1.09451866 |
| 61 | MP0005499_abnormal_olfactory_system | 1.09451866 |
| 62 | MP0004036_abnormal_muscle_relaxation | 1.06560535 |
| 63 | MP0005253_abnormal_eye_physiology | 1.03826063 |
| 64 | MP0003866_abnormal_defecation | 1.03480217 |
| 65 | MP0002210_abnormal_sex_determination | 1.03254756 |
| 66 | MP0003941_abnormal_skin_development | 0.98876284 |
| 67 | MP0003077_abnormal_cell_cycle | 0.98642124 |
| 68 | MP0000013_abnormal_adipose_tissue | 0.95995055 |
| 69 | MP0002938_white_spotting | 0.95924996 |
| 70 | MP0008995_early_reproductive_senescence | 0.93765524 |
| 71 | MP0005083_abnormal_biliary_tract | 0.93413047 |
| 72 | MP0003698_abnormal_male_reproductive | 0.93130896 |
| 73 | MP0005645_abnormal_hypothalamus_physiol | 0.93082961 |
| 74 | MP0002909_abnormal_adrenal_gland | 0.88790791 |
| 75 | MP0001502_abnormal_circadian_rhythm | 0.88685942 |
| 76 | MP0008058_abnormal_DNA_repair | 0.88413559 |
| 77 | MP0000358_abnormal_cell_content/ | 0.87769194 |
| 78 | MP0002277_abnormal_respiratory_mucosa | 0.87741132 |
| 79 | MP0003045_fibrosis | 0.86880751 |
| 80 | MP0001905_abnormal_dopamine_level | 0.85735459 |
| 81 | MP0000372_irregular_coat_pigmentation | 0.85696968 |
| 82 | MP0005195_abnormal_posterior_eye | 0.84473326 |
| 83 | MP0000049_abnormal_middle_ear | 0.84405346 |
| 84 | MP0001764_abnormal_homeostasis | 0.82930139 |
| 85 | MP0004215_abnormal_myocardial_fiber | 0.82756607 |
| 86 | MP0001929_abnormal_gametogenesis | 0.82694091 |
| 87 | MP0005360_urolithiasis | 0.82540761 |
| 88 | MP0003693_abnormal_embryo_hatching | 0.81512940 |
| 89 | MP0001666_abnormal_nutrient_absorption | 0.80662757 |
| 90 | MP0002272_abnormal_nervous_system | 0.79031414 |
| 91 | MP0004957_abnormal_blastocyst_morpholog | 0.78583228 |
| 92 | MP0006292_abnormal_olfactory_placode | 0.77899108 |
| 93 | MP0010368_abnormal_lymphatic_system | 0.77642033 |
| 94 | MP0001119_abnormal_female_reproductive | 0.75536696 |
| 95 | MP0000653_abnormal_sex_gland | 0.74625130 |
| 96 | MP0004019_abnormal_vitamin_homeostasis | 0.73837204 |
| 97 | MP0002572_abnormal_emotion/affect_behav | 0.69923193 |
| 98 | MP0005319_abnormal_enzyme/_coenzyme | 0.69448070 |
| 99 | MP0004085_abnormal_heartbeat | 0.69017717 |
| 100 | MP0002405_respiratory_system_inflammati | 0.68584131 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 4.66207897 |
| 2 | Hepatocellular necrosis (HP:0001404) | 4.59999986 |
| 3 | IgM deficiency (HP:0002850) | 4.50590327 |
| 4 | Hepatic necrosis (HP:0002605) | 4.00584666 |
| 5 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.98868569 |
| 6 | Absent/shortened dynein arms (HP:0200106) | 3.98868569 |
| 7 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.58906471 |
| 8 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.58906471 |
| 9 | B lymphocytopenia (HP:0010976) | 3.58346664 |
| 10 | Increased CSF lactate (HP:0002490) | 3.53831773 |
| 11 | Abnormality of B cell number (HP:0010975) | 3.43371260 |
| 12 | Retrobulbar optic neuritis (HP:0100654) | 3.36624694 |
| 13 | Optic neuritis (HP:0100653) | 3.36624694 |
| 14 | Mitochondrial inheritance (HP:0001427) | 3.36399144 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 3.36374331 |
| 16 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 3.30830424 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.28423795 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.28423795 |
| 19 | Oligodactyly (hands) (HP:0001180) | 3.27330827 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 3.04412928 |
| 21 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.00283278 |
| 22 | Hypothermia (HP:0002045) | 2.98315385 |
| 23 | Central scotoma (HP:0000603) | 2.89546045 |
| 24 | Abnormal ciliary motility (HP:0012262) | 2.88787086 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.87231004 |
| 26 | Orchitis (HP:0100796) | 2.70071942 |
| 27 | Cerebral hypomyelination (HP:0006808) | 2.69801836 |
| 28 | Abnormality of lateral ventricle (HP:0030047) | 2.67829321 |
| 29 | Type I transferrin isoform profile (HP:0003642) | 2.66512923 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.62981470 |
| 31 | Generalized aminoaciduria (HP:0002909) | 2.61618968 |
| 32 | Increased serum lactate (HP:0002151) | 2.57698870 |
| 33 | Microvesicular hepatic steatosis (HP:0001414) | 2.52808937 |
| 34 | Type II lissencephaly (HP:0007260) | 2.50242091 |
| 35 | Duplicated collecting system (HP:0000081) | 2.49022503 |
| 36 | Progressive macrocephaly (HP:0004481) | 2.47585779 |
| 37 | Keratoconjunctivitis (HP:0001096) | 2.46687980 |
| 38 | Hypoplasia of the pons (HP:0012110) | 2.44389284 |
| 39 | Myositis (HP:0100614) | 2.41192226 |
| 40 | Acute encephalopathy (HP:0006846) | 2.39400694 |
| 41 | Abnormality of the pons (HP:0007361) | 2.39236421 |
| 42 | Hypoplastic nipples (HP:0002557) | 2.35282347 |
| 43 | Ileus (HP:0002595) | 2.33680145 |
| 44 | Fair hair (HP:0002286) | 2.33428249 |
| 45 | Hypoplastic pelvis (HP:0008839) | 2.32340386 |
| 46 | Cerebellar dysplasia (HP:0007033) | 2.32045142 |
| 47 | Recurrent sinusitis (HP:0011108) | 2.30821792 |
| 48 | Abnormality of the renal collecting system (HP:0004742) | 2.29284045 |
| 49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.26900014 |
| 50 | Increased serum pyruvate (HP:0003542) | 2.26312701 |
| 51 | Molar tooth sign on MRI (HP:0002419) | 2.22003837 |
| 52 | Abnormality of midbrain morphology (HP:0002418) | 2.22003837 |
| 53 | Abnormal hair whorl (HP:0010721) | 2.21578844 |
| 54 | Scotoma (HP:0000575) | 2.19334397 |
| 55 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.16240296 |
| 56 | Severe combined immunodeficiency (HP:0004430) | 2.15215999 |
| 57 | Hypoproteinemia (HP:0003075) | 2.13962942 |
| 58 | Pancreatic cysts (HP:0001737) | 2.12413163 |
| 59 | IgG deficiency (HP:0004315) | 2.12215709 |
| 60 | Keratoconjunctivitis sicca (HP:0001097) | 2.10799573 |
| 61 | Exertional dyspnea (HP:0002875) | 2.10258336 |
| 62 | Thyroiditis (HP:0100646) | 2.09973126 |
| 63 | Type 2 muscle fiber atrophy (HP:0003554) | 2.07237038 |
| 64 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.03943673 |
| 65 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.03943673 |
| 66 | Abnormal protein glycosylation (HP:0012346) | 2.03943673 |
| 67 | Abnormal glycosylation (HP:0012345) | 2.03943673 |
| 68 | Progressive microcephaly (HP:0000253) | 2.03513713 |
| 69 | Nephronophthisis (HP:0000090) | 2.01469183 |
| 70 | Oligodactyly (HP:0012165) | 2.00652224 |
| 71 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.00461886 |
| 72 | Neoplasm of the oral cavity (HP:0100649) | 1.98649418 |
| 73 | Increased intramyocellular lipid droplets (HP:0012240) | 1.98634447 |
| 74 | Split foot (HP:0001839) | 1.96942892 |
| 75 | Anophthalmia (HP:0000528) | 1.95014308 |
| 76 | Emotional lability (HP:0000712) | 1.94852217 |
| 77 | Hypomagnesemia (HP:0002917) | 1.94143790 |
| 78 | Hypoplastic ischia (HP:0003175) | 1.93326035 |
| 79 | Optic nerve hypoplasia (HP:0000609) | 1.93014360 |
| 80 | Pendular nystagmus (HP:0012043) | 1.92709725 |
| 81 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.92380024 |
| 82 | Chronic hepatic failure (HP:0100626) | 1.91627139 |
| 83 | Abnormality of glycolysis (HP:0004366) | 1.90380806 |
| 84 | Muscle fiber atrophy (HP:0100295) | 1.89199107 |
| 85 | Attenuation of retinal blood vessels (HP:0007843) | 1.88120081 |
| 86 | CNS demyelination (HP:0007305) | 1.84846182 |
| 87 | Mesangial abnormality (HP:0001966) | 1.84769626 |
| 88 | Meckel diverticulum (HP:0002245) | 1.83559800 |
| 89 | Renal Fanconi syndrome (HP:0001994) | 1.82761833 |
| 90 | Barrel-shaped chest (HP:0001552) | 1.82337659 |
| 91 | Abnormality of DNA repair (HP:0003254) | 1.80819849 |
| 92 | Clubbing of toes (HP:0100760) | 1.80466522 |
| 93 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.79200585 |
| 94 | Cerebral edema (HP:0002181) | 1.78113786 |
| 95 | Chromsome breakage (HP:0040012) | 1.77857343 |
| 96 | Abnormality of the ileum (HP:0001549) | 1.77239159 |
| 97 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.76108614 |
| 98 | Respiratory failure (HP:0002878) | 1.75790450 |
| 99 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.75287598 |
| 100 | Optic disc pallor (HP:0000543) | 1.74794998 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 4.71137643 |
| 2 | TRIM28 | 3.24298798 |
| 3 | PINK1 | 3.11170833 |
| 4 | NEK1 | 3.08707456 |
| 5 | BMPR1B | 2.86038971 |
| 6 | TAOK3 | 2.86007442 |
| 7 | ZAK | 2.83701615 |
| 8 | TSSK6 | 2.80301240 |
| 9 | GRK7 | 2.70997775 |
| 10 | NEK9 | 2.22089521 |
| 11 | MAP3K13 | 2.20053160 |
| 12 | GRK1 | 2.19542472 |
| 13 | BRSK2 | 2.16731472 |
| 14 | TLK1 | 2.11949271 |
| 15 | BUB1 | 1.97449802 |
| 16 | CSNK1G2 | 1.81020478 |
| 17 | WNK4 | 1.75029560 |
| 18 | WEE1 | 1.70888198 |
| 19 | CDC7 | 1.69935250 |
| 20 | WNK3 | 1.67430374 |
| 21 | ADRBK2 | 1.66129870 |
| 22 | CSNK1G3 | 1.63346107 |
| 23 | CSNK1G1 | 1.60793448 |
| 24 | MAP3K12 | 1.56632609 |
| 25 | VRK2 | 1.56474546 |
| 26 | DYRK2 | 1.52552806 |
| 27 | TEC | 1.51363173 |
| 28 | PLK3 | 1.40650454 |
| 29 | TNIK | 1.39390175 |
| 30 | STK16 | 1.37723002 |
| 31 | TAF1 | 1.36911077 |
| 32 | CSNK1A1L | 1.35430171 |
| 33 | KDR | 1.30975981 |
| 34 | PRKCI | 1.26155717 |
| 35 | ALK | 1.23957162 |
| 36 | IKBKE | 1.19872794 |
| 37 | STK39 | 1.17713792 |
| 38 | FRK | 1.16140959 |
| 39 | NLK | 1.14752880 |
| 40 | SRPK1 | 1.12583298 |
| 41 | IRAK1 | 1.09274624 |
| 42 | OXSR1 | 1.03873275 |
| 43 | PASK | 1.01553127 |
| 44 | MINK1 | 0.97463473 |
| 45 | KSR1 | 0.96775646 |
| 46 | CAMKK2 | 0.92240480 |
| 47 | BCKDK | 0.89719458 |
| 48 | TXK | 0.87770200 |
| 49 | ACVR1B | 0.84890764 |
| 50 | TBK1 | 0.84063104 |
| 51 | TGFBR1 | 0.83639370 |
| 52 | DAPK1 | 0.79239237 |
| 53 | ADRBK1 | 0.78890408 |
| 54 | SYK | 0.78724104 |
| 55 | NUAK1 | 0.78429076 |
| 56 | MAPK15 | 0.76218072 |
| 57 | TTK | 0.75640007 |
| 58 | VRK1 | 0.74970981 |
| 59 | MAP3K9 | 0.72032767 |
| 60 | BRSK1 | 0.68177332 |
| 61 | LIMK1 | 0.66395034 |
| 62 | ARAF | 0.66330605 |
| 63 | BCR | 0.66221575 |
| 64 | EPHB1 | 0.65753321 |
| 65 | PTK2B | 0.61262450 |
| 66 | FES | 0.60403486 |
| 67 | PIK3CG | 0.59709105 |
| 68 | ATR | 0.58898071 |
| 69 | RPS6KA5 | 0.58321679 |
| 70 | CHEK2 | 0.57681745 |
| 71 | ITK | 0.56598513 |
| 72 | FER | 0.50821722 |
| 73 | EIF2AK3 | 0.49903535 |
| 74 | PLK1 | 0.48328763 |
| 75 | BTK | 0.46761123 |
| 76 | MARK3 | 0.45809221 |
| 77 | MAP3K7 | 0.44522375 |
| 78 | CSK | 0.43537078 |
| 79 | EPHA3 | 0.43245379 |
| 80 | MAP4K1 | 0.40918735 |
| 81 | ATM | 0.40828364 |
| 82 | MAPK13 | 0.40547517 |
| 83 | AURKB | 0.40036936 |
| 84 | PBK | 0.39781657 |
| 85 | LCK | 0.38345794 |
| 86 | GRK5 | 0.38270212 |
| 87 | DAPK2 | 0.37781100 |
| 88 | PHKG1 | 0.37337851 |
| 89 | PHKG2 | 0.37337851 |
| 90 | MKNK2 | 0.37294977 |
| 91 | INSRR | 0.37086570 |
| 92 | MAP2K6 | 0.36843536 |
| 93 | PRKCQ | 0.36563773 |
| 94 | CCNB1 | 0.36561252 |
| 95 | PKN1 | 0.34146553 |
| 96 | CSNK1A1 | 0.30772813 |
| 97 | PRKCG | 0.29042474 |
| 98 | MAP3K11 | 0.29022222 |
| 99 | CSNK1D | 0.26490459 |
| 100 | MKNK1 | 0.26272579 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.96219210 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.04074068 |
| 3 | Phototransduction_Homo sapiens_hsa04744 | 2.94228401 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.88064890 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.68883448 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.68356344 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.67132950 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.64661222 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.46661488 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.00161101 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 1.79508392 |
| 12 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.77748491 |
| 13 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.75174125 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.70640016 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.70353370 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.69589171 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.66037668 |
| 18 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.62776764 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.57434652 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.56832765 |
| 21 | Ribosome_Homo sapiens_hsa03010 | 1.55365576 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.51816529 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.51288571 |
| 24 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.46870547 |
| 25 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.44662035 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.42900882 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.37485004 |
| 28 | RNA transport_Homo sapiens_hsa03013 | 1.36376735 |
| 29 | Allograft rejection_Homo sapiens_hsa05330 | 1.34174657 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.33820356 |
| 31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.31590588 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.29815531 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.29499032 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.28949292 |
| 35 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.27023276 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.26683338 |
| 37 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.26271788 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.26029396 |
| 39 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.22780704 |
| 40 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.20524315 |
| 41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20288048 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.17188170 |
| 43 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.16135660 |
| 44 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.14609990 |
| 45 | Nicotine addiction_Homo sapiens_hsa05033 | 1.14437648 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13928833 |
| 47 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.12159939 |
| 48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.07498441 |
| 49 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.05572503 |
| 50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.04429875 |
| 51 | DNA replication_Homo sapiens_hsa03030 | 0.99618302 |
| 52 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.99359524 |
| 53 | Spliceosome_Homo sapiens_hsa03040 | 0.97477357 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.93582883 |
| 55 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92511720 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.90440292 |
| 57 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.89444842 |
| 58 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.88930822 |
| 59 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.88587349 |
| 60 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.83654124 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.82914778 |
| 62 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80715221 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73651023 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.72973035 |
| 65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.69119385 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67556945 |
| 67 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65203157 |
| 68 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.64319909 |
| 69 | Circadian rhythm_Homo sapiens_hsa04710 | 0.64252826 |
| 70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.64062071 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63155316 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62180143 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.60740907 |
| 74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58569134 |
| 75 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.58550776 |
| 76 | Mineral absorption_Homo sapiens_hsa04978 | 0.55269251 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55113654 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.55021361 |
| 79 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.53142165 |
| 80 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.52642782 |
| 81 | Morphine addiction_Homo sapiens_hsa05032 | 0.50050965 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49530768 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48023839 |
| 84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46756161 |
| 85 | Viral myocarditis_Homo sapiens_hsa05416 | 0.45437698 |
| 86 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45142556 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.43993615 |
| 88 | Peroxisome_Homo sapiens_hsa04146 | 0.43442832 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41666618 |
| 90 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.39082068 |
| 91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.38575181 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38245373 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.37122545 |
| 94 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37017960 |
| 95 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.36664093 |
| 96 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.36068251 |
| 97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.33591523 |
| 98 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32928568 |
| 99 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.32504428 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.31563436 |

