PSTK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1energy coupled proton transport, down electrochemical gradient (GO:0015985)4.51316495
2ATP synthesis coupled proton transport (GO:0015986)4.51316495
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.48207189
4ribosomal small subunit assembly (GO:0000028)4.46784553
5ribosomal large subunit biogenesis (GO:0042273)4.29829490
6regulation of mitochondrial translation (GO:0070129)4.24828684
7mitochondrial respiratory chain complex I assembly (GO:0032981)4.18746176
8NADH dehydrogenase complex assembly (GO:0010257)4.18746176
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.18746176
10behavioral response to nicotine (GO:0035095)4.09512079
11proteasome assembly (GO:0043248)3.97526470
12protein complex biogenesis (GO:0070271)3.95083310
13platelet dense granule organization (GO:0060155)3.91634437
14maturation of SSU-rRNA (GO:0030490)3.90879626
15mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.86944230
16mitochondrial respiratory chain complex assembly (GO:0033108)3.83829112
17deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.80022485
18DNA deamination (GO:0045006)3.79832803
19pseudouridine synthesis (GO:0001522)3.78283933
20oxidative phosphorylation (GO:0006119)3.69915131
21chromatin remodeling at centromere (GO:0031055)3.69388987
22CENP-A containing nucleosome assembly (GO:0034080)3.68831384
23DNA replication initiation (GO:0006270)3.64944396
24polyketide metabolic process (GO:0030638)3.60054765
25doxorubicin metabolic process (GO:0044598)3.60054765
26daunorubicin metabolic process (GO:0044597)3.60054765
27respiratory electron transport chain (GO:0022904)3.58702651
28purine nucleobase biosynthetic process (GO:0009113)3.55049317
29nucleobase biosynthetic process (GO:0046112)3.53567528
30quinone biosynthetic process (GO:1901663)3.52533299
31ubiquinone biosynthetic process (GO:0006744)3.52533299
32telomere maintenance via semi-conservative replication (GO:0032201)3.52479223
33electron transport chain (GO:0022900)3.50131529
34IMP biosynthetic process (GO:0006188)3.50125583
35ribosomal small subunit biogenesis (GO:0042274)3.44065165
36ribonucleoprotein complex biogenesis (GO:0022613)3.41787097
37DNA strand elongation involved in DNA replication (GO:0006271)3.37588552
38viral transcription (GO:0019083)3.36425078
39detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.34006042
40translational termination (GO:0006415)3.32223701
41cellular component biogenesis (GO:0044085)3.30619157
42IMP metabolic process (GO:0046040)3.29865406
43pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.26948097
44DNA strand elongation (GO:0022616)3.25729772
45protein-cofactor linkage (GO:0018065)3.25240896
46RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.25164320
47transcription elongation from RNA polymerase I promoter (GO:0006362)3.23714552
48pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.23097254
49L-fucose catabolic process (GO:0042355)3.20736378
50fucose catabolic process (GO:0019317)3.20736378
51L-fucose metabolic process (GO:0042354)3.20736378
52water-soluble vitamin biosynthetic process (GO:0042364)3.20547069
53termination of RNA polymerase III transcription (GO:0006386)3.19341074
54transcription elongation from RNA polymerase III promoter (GO:0006385)3.19341074
55termination of RNA polymerase I transcription (GO:0006363)3.13720691
56ribosome biogenesis (GO:0042254)3.13593976
57telomere maintenance via recombination (GO:0000722)3.12564821
58protein polyglutamylation (GO:0018095)3.12285244
59transcription-coupled nucleotide-excision repair (GO:0006283)3.12068475
60establishment of protein localization to mitochondrial membrane (GO:0090151)3.11620488
61piRNA metabolic process (GO:0034587)3.10617895
62response to pheromone (GO:0019236)3.10484033
63DNA double-strand break processing (GO:0000729)3.07827489
64L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.07127312
65* translational elongation (GO:0006414)3.05804003
66ubiquinone metabolic process (GO:0006743)3.02729238
67spliceosomal complex assembly (GO:0000245)3.02261978
68regulation of helicase activity (GO:0051095)3.01908625
69histone H2A acetylation (GO:0043968)3.01615708
707-methylguanosine mRNA capping (GO:0006370)3.00807526
71viral mRNA export from host cell nucleus (GO:0046784)2.99397601
72GTP biosynthetic process (GO:0006183)2.95778523
73kynurenine metabolic process (GO:0070189)2.95483561
74pyrimidine nucleotide catabolic process (GO:0006244)2.94500027
757-methylguanosine RNA capping (GO:0009452)2.94265158
76RNA capping (GO:0036260)2.94265158
77deoxyribose phosphate biosynthetic process (GO:0046385)2.94071606
782-deoxyribonucleotide biosynthetic process (GO:0009265)2.94071606
79protein K6-linked ubiquitination (GO:0085020)2.93920046
80mitochondrial RNA metabolic process (GO:0000959)2.92068998
81negative regulation of telomere maintenance (GO:0032205)2.91237781
82cellular ketone body metabolic process (GO:0046950)2.90804722
83negative regulation of DNA-dependent DNA replication (GO:2000104)2.90113768
84preassembly of GPI anchor in ER membrane (GO:0016254)2.89776384
85transcription from RNA polymerase I promoter (GO:0006360)2.89404205
86amine catabolic process (GO:0009310)2.89146220
87cellular biogenic amine catabolic process (GO:0042402)2.89146220
88translation (GO:0006412)2.88839421
89mitotic recombination (GO:0006312)2.88504753
90base-excision repair, AP site formation (GO:0006285)2.88467284
91intra-S DNA damage checkpoint (GO:0031573)2.88026054
92deoxyribonucleotide biosynthetic process (GO:0009263)2.87988160
93nucleotide-excision repair, DNA gap filling (GO:0006297)2.87828688
94rRNA modification (GO:0000154)2.87718762
95indolalkylamine metabolic process (GO:0006586)2.86996447
96regulation of nuclear cell cycle DNA replication (GO:0033262)2.86198266
97regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.85023144
98regulation of mitotic spindle checkpoint (GO:1903504)2.85023144
99negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.84880700
100DNA replication checkpoint (GO:0000076)2.84860687
101deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.84444012
102cullin deneddylation (GO:0010388)2.83665162
103protein neddylation (GO:0045116)2.83230699
104tryptophan catabolic process (GO:0006569)2.82770109
105indole-containing compound catabolic process (GO:0042436)2.82770109
106indolalkylamine catabolic process (GO:0046218)2.82770109
107respiratory chain complex IV assembly (GO:0008535)2.80444387
108guanosine-containing compound biosynthetic process (GO:1901070)2.80235014
109exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.79638521
110recombinational repair (GO:0000725)2.79112163
111mannosylation (GO:0097502)2.79052523
112tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.78786106
113RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.78786106
114tRNA methylation (GO:0030488)2.78650510
115peptidyl-histidine modification (GO:0018202)2.78451656
116pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.77584500
117kinetochore organization (GO:0051383)2.77423871
118reciprocal DNA recombination (GO:0035825)2.75756315
119reciprocal meiotic recombination (GO:0007131)2.75756315
120ribosome assembly (GO:0042255)2.74941125
121telomere maintenance via telomere lengthening (GO:0010833)2.74482542
122pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.74353708
123L-methionine salvage (GO:0071267)2.72709009
124L-methionine biosynthetic process (GO:0071265)2.72709009
125amino acid salvage (GO:0043102)2.72709009
126double-strand break repair via homologous recombination (GO:0000724)2.71111135
127cilium morphogenesis (GO:0060271)2.70615589
128cytochrome complex assembly (GO:0017004)2.70569071
129metallo-sulfur cluster assembly (GO:0031163)2.70451546
130iron-sulfur cluster assembly (GO:0016226)2.70451546
131rRNA processing (GO:0006364)2.70340357
132galactose catabolic process (GO:0019388)2.70297869
133nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.70170186
134kinetochore assembly (GO:0051382)2.70065592
135DNA damage response, detection of DNA damage (GO:0042769)2.69578167
136meiotic chromosome segregation (GO:0045132)2.69342593
137formation of translation preinitiation complex (GO:0001731)2.69126904
138chaperone-mediated protein transport (GO:0072321)2.67414430
139DNA replication-independent nucleosome organization (GO:0034724)2.67347891
140DNA replication-independent nucleosome assembly (GO:0006336)2.67347891
141positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.66955729
142ketone body metabolic process (GO:1902224)2.66288632
143regulation of neurotransmitter uptake (GO:0051580)2.66034925
144protein deneddylation (GO:0000338)2.65926761
145positive regulation of mitochondrial fission (GO:0090141)2.65709215
146SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.65644020
147mitochondrion morphogenesis (GO:0070584)2.63774695
148tryptophan metabolic process (GO:0006568)2.63510312
149retinal cone cell development (GO:0046549)2.62321093
150tRNA processing (GO:0008033)2.61722556
151intracellular protein transmembrane import (GO:0044743)2.58591913
152anterograde synaptic vesicle transport (GO:0048490)2.57559494
153regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.56747513
154regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.56747513
155replication fork processing (GO:0031297)2.56502230
156rRNA methylation (GO:0031167)2.53626174
157auditory receptor cell stereocilium organization (GO:0060088)2.52681483
158detection of light stimulus involved in sensory perception (GO:0050962)2.52546645
159detection of light stimulus involved in visual perception (GO:0050908)2.52546645
160dopamine transport (GO:0015872)2.52442638
161reflex (GO:0060004)2.50424669
162regulation of meiosis I (GO:0060631)2.49175368
163epithelial cilium movement (GO:0003351)2.47422231
164somatic hypermutation of immunoglobulin genes (GO:0016446)2.45449330
165somatic diversification of immune receptors via somatic mutation (GO:0002566)2.45449330
166regulation of glucokinase activity (GO:0033131)2.45432842
167regulation of hexokinase activity (GO:1903299)2.45432842
168negative regulation of mast cell activation (GO:0033004)2.45258360
169epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.45046107
170DNA methylation involved in gamete generation (GO:0043046)2.44434767

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.19208620
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.43609121
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.25039185
4ZNF274_21170338_ChIP-Seq_K562_Hela4.03071420
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.36876534
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.35815682
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.32058689
8RBPJ_22232070_ChIP-Seq_NCS_Mouse3.30278030
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.30144336
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.99889180
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.97123019
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.89524368
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.87579471
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83702184
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.82072233
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.78066821
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.74397912
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.70580326
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.67013012
20VDR_23849224_ChIP-Seq_CD4+_Human2.64272092
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.56180112
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.55785926
23IGF1R_20145208_ChIP-Seq_DFB_Human2.53196459
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.51819119
25SALL1_21062744_ChIP-ChIP_HESCs_Human2.49841287
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.49034383
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.46793903
28* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.44811784
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.40390851
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.37481515
31* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.32764730
32NOTCH1_21737748_ChIP-Seq_TLL_Human2.32480011
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.31931938
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.30673272
35ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19966472
36ELF1_17652178_ChIP-ChIP_JURKAT_Human2.19485206
37THAP11_20581084_ChIP-Seq_MESCs_Mouse2.18027422
38FOXP3_21729870_ChIP-Seq_TREG_Human2.12144566
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.06244908
40* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05963732
41FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.00822244
42DCP1A_22483619_ChIP-Seq_HELA_Human1.96477758
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.95876549
44IRF1_19129219_ChIP-ChIP_H3396_Human1.95007248
45TAF15_26573619_Chip-Seq_HEK293_Human1.93807026
46ELK1_19687146_ChIP-ChIP_HELA_Human1.88395408
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87371214
48P300_19829295_ChIP-Seq_ESCs_Human1.84847479
49XRN2_22483619_ChIP-Seq_HELA_Human1.83052603
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.82729397
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80871530
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.80468921
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.78823741
54FUS_26573619_Chip-Seq_HEK293_Human1.76483585
55TTF2_22483619_ChIP-Seq_HELA_Human1.70944211
56E2F1_21310950_ChIP-Seq_MCF-7_Human1.68116814
57* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.67750241
58SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62636430
59CIITA_25753668_ChIP-Seq_RAJI_Human1.57068086
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.56240643
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53128021
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.50139024
63ER_23166858_ChIP-Seq_MCF-7_Human1.49603322
64PCGF2_27294783_Chip-Seq_ESCs_Mouse1.47932725
65* TP53_22573176_ChIP-Seq_HFKS_Human1.45009535
66TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43835811
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43331304
68* GABP_19822575_ChIP-Seq_HepG2_Human1.40681865
69BCAT_22108803_ChIP-Seq_LS180_Human1.39385643
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38459634
71* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.34673964
72* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.34385321
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.33261553
74NANOG_19829295_ChIP-Seq_ESCs_Human1.32887017
75SOX2_19829295_ChIP-Seq_ESCs_Human1.32887017
76CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.29568466
77MYC_18940864_ChIP-ChIP_HL60_Human1.29061272
78KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.28627217
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28330989
80AR_21909140_ChIP-Seq_LNCAP_Human1.25104313
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24921059
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.24547586
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23942975
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22743087
85MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20642080
86SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20400714
87CBP_20019798_ChIP-Seq_JUKART_Human1.20139682
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20139682
89FOXA1_27270436_Chip-Seq_PROSTATE_Human1.18433216
90FOXA1_25329375_ChIP-Seq_VCAP_Human1.18433216
91EWS_26573619_Chip-Seq_HEK293_Human1.18273573
92GATA1_22025678_ChIP-Seq_K562_Human1.17467133
93AR_25329375_ChIP-Seq_VCAP_Human1.15235592
94NFE2_27457419_Chip-Seq_LIVER_Mouse1.13088999
95* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.13031800
96TCF4_22108803_ChIP-Seq_LS180_Human1.11067082
97SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10589826
98STAT3_23295773_ChIP-Seq_U87_Human1.09805906
99TCF4_23295773_ChIP-Seq_U87_Human1.09728471
100BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08507222
101SMAD4_21799915_ChIP-Seq_A2780_Human1.08016940
102POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07584020
103* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.07128336
104PIAS1_25552417_ChIP-Seq_VCAP_Human1.05406544
105BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05163508
106AR_20517297_ChIP-Seq_VCAP_Human1.03637915
107CBX2_27304074_Chip-Seq_ESCs_Mouse1.03412732
108KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03247583
109NCOR_22424771_ChIP-Seq_293T_Human1.03226228
110FOXA1_21572438_ChIP-Seq_LNCaP_Human1.03022591
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.01907460
112SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01739482
113SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01038980
114TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00701598
115PADI4_21655091_ChIP-ChIP_MCF-7_Human1.00682732
116SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.00253034
117RNF2_27304074_Chip-Seq_NSC_Mouse0.99747251
118SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99024461
119POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98404393
120FLI1_21867929_ChIP-Seq_TH2_Mouse0.97590193
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97535459
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97535459
123GBX2_23144817_ChIP-Seq_PC3_Human0.97457614
124GATA3_21878914_ChIP-Seq_MCF-7_Human0.97341196
125FOXM1_23109430_ChIP-Seq_U2OS_Human0.96804703
126SMAD3_21741376_ChIP-Seq_EPCs_Human0.95485417
127HOXB7_26014856_ChIP-Seq_BT474_Human0.95346952
128* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95207618
129PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95072931
130NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.93267444
131CRX_20693478_ChIP-Seq_RETINA_Mouse0.92782373
132MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.87199703
133* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86548106
134* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86409831
135CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.85929954
136TP63_19390658_ChIP-ChIP_HaCaT_Human0.83989097
137CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.83859978
138ELK1_22589737_ChIP-Seq_MCF10A_Human0.83219716
139RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.78843852
140PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77769993
141VDR_22108803_ChIP-Seq_LS180_Human0.77284446
142POU3F2_20337985_ChIP-ChIP_501MEL_Human0.77228561
143ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.76607519
144EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75715156
145SOX2_16153702_ChIP-ChIP_HESCs_Human0.73704802
146GATA4_21415370_ChIP-Seq_HL-1_Mouse0.73482656
147EZH2_27294783_Chip-Seq_NPCs_Mouse0.72735895
148NANOG_16153702_ChIP-ChIP_HESCs_Human0.72672307
149SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.72591100
150IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.72577498
151E2F1_18555785_Chip-Seq_ESCs_Mouse0.72372611
152NMYC_18555785_Chip-Seq_ESCs_Mouse0.71559367
153CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71405147
154STAT3_18555785_Chip-Seq_ESCs_Mouse0.70617473
155* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.70181507

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.42492673
2MP0010094_abnormal_chromosome_stability3.20693726
3MP0004215_abnormal_myocardial_fiber3.15895602
4MP0004147_increased_porphyrin_level3.13521067
5MP0002102_abnormal_ear_morphology3.02038371
6MP0001188_hyperpigmentation2.90087954
7MP0008058_abnormal_DNA_repair2.88152641
8MP0009697_abnormal_copulation2.85273792
9MP0000569_abnormal_digit_pigmentation2.58467697
10MP0003111_abnormal_nucleus_morphology2.43762895
11MP0003195_calcinosis2.42600336
12MP0003077_abnormal_cell_cycle2.41908100
13MP0008007_abnormal_cellular_replicative2.39969395
14MP0003646_muscle_fatigue2.37478181
15MP0009379_abnormal_foot_pigmentation2.31603370
16MP0009046_muscle_twitch2.28253599
17MP0001986_abnormal_taste_sensitivity2.27772024
18MP0000749_muscle_degeneration2.22880239
19MP0004484_altered_response_of2.16430916
20MP0008057_abnormal_DNA_replication2.14567894
21MP0002127_abnormal_cardiovascular_syste2.09908419
22MP0004957_abnormal_blastocyst_morpholog2.08548743
23MP0006036_abnormal_mitochondrial_physio2.05907572
24MP0005084_abnormal_gallbladder_morpholo1.99158288
25MP0003123_paternal_imprinting1.99024277
26MP0004084_abnormal_cardiac_muscle1.96866272
27MP0002653_abnormal_ependyma_morphology1.94469292
28MP0005409_darkened_coat_color1.90393421
29MP0008872_abnormal_physiological_respon1.84956216
30MP0003828_pulmonary_edema1.82974867
31MP0006292_abnormal_olfactory_placode1.82842399
32MP0004145_abnormal_muscle_electrophysio1.81753484
33MP0003763_abnormal_thymus_physiology1.81172895
34MP0002396_abnormal_hematopoietic_system1.74051374
35MP0003567_abnormal_fetal_cardiomyocyte1.71437108
36MP0005646_abnormal_pituitary_gland1.70298907
37MP0003137_abnormal_impulse_conducting1.66022121
38MP0002928_abnormal_bile_duct1.66002432
39MP0001529_abnormal_vocalization1.63677696
40MP0005330_cardiomyopathy1.61981947
41MP0000631_abnormal_neuroendocrine_gland1.60842308
42MP0003941_abnormal_skin_development1.58460739
43MP0000751_myopathy1.57757303
44MP0008995_early_reproductive_senescence1.55159700
45MP0008875_abnormal_xenobiotic_pharmacok1.54963474
46MP0009745_abnormal_behavioral_response1.54505181
47MP0001984_abnormal_olfaction1.49604029
48MP0002736_abnormal_nociception_after1.49466181
49MP0004036_abnormal_muscle_relaxation1.49325781
50MP0001486_abnormal_startle_reflex1.47963165
51MP0002272_abnormal_nervous_system1.44773379
52MP0005645_abnormal_hypothalamus_physiol1.43856716
53MP0006035_abnormal_mitochondrial_morpho1.43216023
54MP0000015_abnormal_ear_pigmentation1.42706804
55MP0002972_abnormal_cardiac_muscle1.42627071
56MP0006276_abnormal_autonomic_nervous1.40392457
57MP0001853_heart_inflammation1.37733064
58MP0001485_abnormal_pinna_reflex1.37090411
59MP0005670_abnormal_white_adipose1.34743997
60MP0002277_abnormal_respiratory_mucosa1.34039174
61MP0008932_abnormal_embryonic_tissue1.33346902
62MP0001905_abnormal_dopamine_level1.32372195
63MP0000427_abnormal_hair_cycle1.32060915
64MP0005075_abnormal_melanosome_morpholog1.27778213
65MP0002938_white_spotting1.27678500
66MP0004808_abnormal_hematopoietic_stem1.21522026
67MP0003121_genomic_imprinting1.20343483
68MP0005620_abnormal_muscle_contractility1.17987431
69MP0002876_abnormal_thyroid_physiology1.17834587
70MP0005385_cardiovascular_system_phenoty1.17702127
71MP0001544_abnormal_cardiovascular_syste1.17702127
72MP0000490_abnormal_crypts_of1.17277672
73MP0003890_abnormal_embryonic-extraembry1.17061139
74MP0002837_dystrophic_cardiac_calcinosis1.16837036
75MP0005174_abnormal_tail_pigmentation1.15504300
76MP0005671_abnormal_response_to1.15262385
77MP0004142_abnormal_muscle_tone1.15157421
78MP0010386_abnormal_urinary_bladder1.14012403
79MP0000566_synostosis1.12870016
80MP0000383_abnormal_hair_follicle1.12861241
81MP0003718_maternal_effect1.11996753
82MP0002572_abnormal_emotion/affect_behav1.11089233
83MP0001968_abnormal_touch/_nociception1.11015576
84MP0001929_abnormal_gametogenesis1.10506350
85MP0002733_abnormal_thermal_nociception1.09410743
86MP0002095_abnormal_skin_pigmentation1.09081276
87MP0003880_abnormal_central_pattern1.07723122
88MP0008877_abnormal_DNA_methylation1.07266685
89MP0003186_abnormal_redox_activity1.07214001
90MP0002067_abnormal_sensory_capabilities1.06822159
91MP0008775_abnormal_heart_ventricle1.06767724
92MP0001293_anophthalmia1.06669647
93MP0002160_abnormal_reproductive_system1.06527024
94MP0000703_abnormal_thymus_morphology1.04978876
95MP0003136_yellow_coat_color1.04773189
96MP0003786_premature_aging1.04163657
97MP0001970_abnormal_pain_threshold1.04118821
98MP0003011_delayed_dark_adaptation1.01718430
99MP0001501_abnormal_sleep_pattern1.01508347
100MP0003698_abnormal_male_reproductive1.00263812
101MP0008789_abnormal_olfactory_epithelium0.99788558
102MP0004885_abnormal_endolymph0.99391442
103MP0006072_abnormal_retinal_apoptosis0.98433738
104MP0004133_heterotaxia0.97964784
105MP0005171_absent_coat_pigmentation0.97374161
106MP0005389_reproductive_system_phenotype0.97034996
107MP0000313_abnormal_cell_death0.96909016
108MP0004924_abnormal_behavior0.96347246
109MP0005386_behavior/neurological_phenoty0.96347246
110MP0003938_abnormal_ear_development0.95807610
111MP0002557_abnormal_social/conspecific_i0.95239045
112MP0002106_abnormal_muscle_physiology0.95097516
113MP0005410_abnormal_fertilization0.94278885
114MP0003119_abnormal_digestive_system0.93090668
115MP0004742_abnormal_vestibular_system0.92908164
116MP0003943_abnormal_hepatobiliary_system0.92798965
117MP0006138_congestive_heart_failure0.91468591
118MP0000653_abnormal_sex_gland0.91136059
119MP0005551_abnormal_eye_electrophysiolog0.89605914
120MP0002638_abnormal_pupillary_reflex0.88660584
121MP0002075_abnormal_coat/hair_pigmentati0.88143615
122MP0010630_abnormal_cardiac_muscle0.87919977
123MP0002064_seizures0.87656056
124MP0005253_abnormal_eye_physiology0.87638488
125MP0001764_abnormal_homeostasis0.84279225
126MP0000049_abnormal_middle_ear0.84004988
127MP0003937_abnormal_limbs/digits/tail_de0.83372439
128MP0005195_abnormal_posterior_eye0.82868869
129MP0002254_reproductive_system_inflammat0.82612346
130MP0001502_abnormal_circadian_rhythm0.82314198
131MP0001145_abnormal_male_reproductive0.82245000
132MP0000026_abnormal_inner_ear0.81590046
133MP0000647_abnormal_sebaceous_gland0.81418793
134MP0002735_abnormal_chemical_nociception0.80914834
135MP0001324_abnormal_eye_pigmentation0.80582890
136MP0002063_abnormal_learning/memory/cond0.80578307
137MP0002752_abnormal_somatic_nervous0.79392134
138MP0000689_abnormal_spleen_morphology0.79163874
139MP0002234_abnormal_pharynx_morphology0.78735002
140MP0004043_abnormal_pH_regulation0.78634692
141MP0001119_abnormal_female_reproductive0.78066197
142MP0004085_abnormal_heartbeat0.77327143
143MP0002722_abnormal_immune_system0.77229814
144MP0001186_pigmentation_phenotype0.75604057
145MP0004087_abnormal_muscle_fiber0.74513989
146MP0000350_abnormal_cell_proliferation0.74312200
147MP0003221_abnormal_cardiomyocyte_apopto0.73097559
148MP0000372_irregular_coat_pigmentation0.70982868
149MP0005369_muscle_phenotype0.67425092
150MP0003315_abnormal_perineum_morphology0.66876348
151MP0002210_abnormal_sex_determination0.66559302
152MP0003787_abnormal_imprinting0.66413069
153MP0002398_abnormal_bone_marrow0.66144376
154MP0002019_abnormal_tumor_incidence0.64746179
155MP0003806_abnormal_nucleotide_metabolis0.64681522
156MP0002751_abnormal_autonomic_nervous0.61828342
157MP0002269_muscular_atrophy0.60630928
158MP0002132_abnormal_respiratory_system0.59316951
159MP0004381_abnormal_hair_follicle0.59159466

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.41678576
2Acute necrotizing encephalopathy (HP:0006965)4.21211866
3Pancreatic fibrosis (HP:0100732)4.09016962
4True hermaphroditism (HP:0010459)4.01512898
5Molar tooth sign on MRI (HP:0002419)3.97389664
6Abnormality of midbrain morphology (HP:0002418)3.97389664
7Abnormal mitochondria in muscle tissue (HP:0008316)3.84794588
8Mitochondrial inheritance (HP:0001427)3.78993685
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.69567664
10Hepatocellular necrosis (HP:0001404)3.68601019
11Increased CSF lactate (HP:0002490)3.57050689
12Progressive macrocephaly (HP:0004481)3.54414367
13Reticulocytopenia (HP:0001896)3.51066124
14Birth length less than 3rd percentile (HP:0003561)3.46974293
15Hepatic necrosis (HP:0002605)3.46619563
16Acute encephalopathy (HP:0006846)3.40775118
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.39320717
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.39320717
19Chromsome breakage (HP:0040012)3.38162723
20Medial flaring of the eyebrow (HP:0010747)3.36650384
21Type I transferrin isoform profile (HP:0003642)3.32378804
22Nephronophthisis (HP:0000090)3.29177593
23Microvesicular hepatic steatosis (HP:0001414)3.25494421
24Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.22470006
25Abnormality of alanine metabolism (HP:0010916)3.22470006
26Hyperalaninemia (HP:0003348)3.22470006
27Increased serum lactate (HP:0002151)3.19879140
28Abnormality of DNA repair (HP:0003254)3.06654141
29Type II lissencephaly (HP:0007260)3.04034633
30Gait imbalance (HP:0002141)3.02706500
31Abnormality of glycolysis (HP:0004366)3.02620185
32Increased serum pyruvate (HP:0003542)3.02620185
333-Methylglutaconic aciduria (HP:0003535)3.00128976
34Congenital primary aphakia (HP:0007707)2.98772399
35Congenital stationary night blindness (HP:0007642)2.95621087
36Exercise intolerance (HP:0003546)2.94855333
37Lactic acidosis (HP:0003128)2.94575773
38Abnormality of the preputium (HP:0100587)2.87280170
39Nephrogenic diabetes insipidus (HP:0009806)2.72247359
40Meckel diverticulum (HP:0002245)2.70592996
41Abnormality of the renal medulla (HP:0100957)2.68455603
42Abnormality of the renal cortex (HP:0011035)2.64739977
43Increased hepatocellular lipid droplets (HP:0006565)2.63154272
44Cystic liver disease (HP:0006706)2.61056552
45Abnormality of secondary sexual hair (HP:0009888)2.57778434
46Abnormality of the axillary hair (HP:0100134)2.57778434
47Sclerocornea (HP:0000647)2.57091013
48Abnormality of the ileum (HP:0001549)2.52418286
49Aplasia/Hypoplasia of the uvula (HP:0010293)2.50467494
50Chronic hepatic failure (HP:0100626)2.48093956
51Breast hypoplasia (HP:0003187)2.46780129
52Congenital, generalized hypertrichosis (HP:0004540)2.46537597
53Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.44163036
54Optic disc pallor (HP:0000543)2.43290730
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41357256
56Lipid accumulation in hepatocytes (HP:0006561)2.41286603
57Cerebral edema (HP:0002181)2.40802225
58Dry hair (HP:0011359)2.36654915
59Respiratory failure (HP:0002878)2.34975989
60Double outlet right ventricle (HP:0001719)2.33939591
61Congenital malformation of the right heart (HP:0011723)2.33939591
62Macrocytic anemia (HP:0001972)2.32391813
63Calf muscle hypertrophy (HP:0008981)2.30590826
64Inability to walk (HP:0002540)2.30440054
65Pendular nystagmus (HP:0012043)2.29000714
66Aplasia/Hypoplasia of the tongue (HP:0010295)2.28646322
67Attenuation of retinal blood vessels (HP:0007843)2.27974826
68Furrowed tongue (HP:0000221)2.27918713
69Genital tract atresia (HP:0001827)2.27107356
70Absent thumb (HP:0009777)2.25915768
71Cerebellar dysplasia (HP:0007033)2.25830799
72Large for gestational age (HP:0001520)2.24981288
73Methylmalonic acidemia (HP:0002912)2.24069749
74Abnormal protein glycosylation (HP:0012346)2.23389709
75Abnormal glycosylation (HP:0012345)2.23389709
76Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23389709
77Abnormal protein N-linked glycosylation (HP:0012347)2.23389709
78Poor coordination (HP:0002370)2.22777340
79Vaginal atresia (HP:0000148)2.22399931
80Anencephaly (HP:0002323)2.20503138
81Abnormality of the renal collecting system (HP:0004742)2.19913306
82Bile duct proliferation (HP:0001408)2.19874216
83Abnormal biliary tract physiology (HP:0012439)2.19874216
84Megaloblastic anemia (HP:0001889)2.17675626
85Hyperventilation (HP:0002883)2.16345003
86Abnormality of chromosome stability (HP:0003220)2.16213960
87Abnormality of the labia minora (HP:0012880)2.15633302
88Tubular atrophy (HP:0000092)2.12782489
89Duplicated collecting system (HP:0000081)2.12655137
90Muscle hypertrophy of the lower extremities (HP:0008968)2.11800560
91Abnormal drinking behavior (HP:0030082)2.10565345
92Polydipsia (HP:0001959)2.10565345
93Supernumerary spleens (HP:0009799)2.09191603
94Male pseudohermaphroditism (HP:0000037)2.07869374
95Congenital hepatic fibrosis (HP:0002612)2.07799737
96Gaze-evoked nystagmus (HP:0000640)2.07224693
97Intestinal atresia (HP:0011100)2.06956096
98Lissencephaly (HP:0001339)2.06928622
99Hypothermia (HP:0002045)2.06804883
100Methylmalonic aciduria (HP:0012120)2.05836808
101Selective tooth agenesis (HP:0001592)2.03965874
102Abnormality of cells of the erythroid lineage (HP:0012130)2.03766481
103Increased intramyocellular lipid droplets (HP:0012240)2.02933990
104Abolished electroretinogram (ERG) (HP:0000550)2.02637941
105Thyroid-stimulating hormone excess (HP:0002925)2.02451554
106Hypoplastic left heart (HP:0004383)2.02236298
107Bone marrow hypocellularity (HP:0005528)2.01862185
108Small intestinal stenosis (HP:0012848)2.01851529
109Duodenal stenosis (HP:0100867)2.01851529
110Febrile seizures (HP:0002373)2.01512601
111Abnormality of the columella (HP:0009929)2.01207541
112Progressive cerebellar ataxia (HP:0002073)2.00222923
113Reduced antithrombin III activity (HP:0001976)2.00170864
114Pancytopenia (HP:0001876)1.99958328
115Triphalangeal thumb (HP:0001199)1.99704485
116Retinal dysplasia (HP:0007973)1.98233574
117Pallor (HP:0000980)1.98210993
118Ragged-red muscle fibers (HP:0003200)1.97785656
119Abnormal rod and cone electroretinograms (HP:0008323)1.96746991
120Progressive inability to walk (HP:0002505)1.96557151
121Severe muscular hypotonia (HP:0006829)1.96323415
122Abnormal number of erythroid precursors (HP:0012131)1.95053888
123Sparse eyelashes (HP:0000653)1.93960868
124Rhabdomyolysis (HP:0003201)1.92584970
12511 pairs of ribs (HP:0000878)1.91636901
126Broad-based gait (HP:0002136)1.90689099
127Aplasia/Hypoplasia of the tibia (HP:0005772)1.90200278
128Clubbing of toes (HP:0100760)1.89878428
129Supraventricular tachycardia (HP:0004755)1.89760655
130Abnormality of the vitamin B12 metabolism (HP:0004341)1.88744355
131Renal cortical cysts (HP:0000803)1.87564285
132Sloping forehead (HP:0000340)1.87312150
133Oral leukoplakia (HP:0002745)1.86878191
134Postaxial foot polydactyly (HP:0001830)1.86350610
135Optic nerve hypoplasia (HP:0000609)1.86001244
136Occipital encephalocele (HP:0002085)1.85488325
137Atrial fibrillation (HP:0005110)1.84619270
138Colon cancer (HP:0003003)1.84479575
139Abnormality of the pons (HP:0007361)1.82104475
140Hydroureter (HP:0000072)1.81262028
141Volvulus (HP:0002580)1.80408878
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.80320505
143Abnormal lung lobation (HP:0002101)1.80183425
144Homocystinuria (HP:0002156)1.80110577
145Abnormality of homocysteine metabolism (HP:0010919)1.80110577
146Supraventricular arrhythmia (HP:0005115)1.79596450
147Hyperglycinemia (HP:0002154)1.79356941
148Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.79031533
149Preaxial hand polydactyly (HP:0001177)1.78697578
150Dandy-Walker malformation (HP:0001305)1.78265270
151Hypoplasia of the pons (HP:0012110)1.78226915
152Respiratory difficulties (HP:0002880)1.77208177
153Progressive microcephaly (HP:0000253)1.76047841
154Aplasia cutis congenita (HP:0001057)1.75831962
155Delayed CNS myelination (HP:0002188)1.75465811
156Patellar aplasia (HP:0006443)1.75184012
157Stomach cancer (HP:0012126)1.74115565
158Renal Fanconi syndrome (HP:0001994)1.73576568
159Premature graying of hair (HP:0002216)1.73211103
160Abnormality of the duodenum (HP:0002246)1.72113912
161Aganglionic megacolon (HP:0002251)1.71678650
162Astigmatism (HP:0000483)1.71286941
163Aplasia/hypoplasia of the uterus (HP:0008684)1.71069782
164Increased muscle lipid content (HP:0009058)1.70965338
165Rimmed vacuoles (HP:0003805)1.70744937
166Aplasia involving forearm bones (HP:0009822)1.70535423
167Absent forearm bone (HP:0003953)1.70535423
168Small hand (HP:0200055)1.70021011
169Cerebral hypomyelination (HP:0006808)1.70003004
170Primary atrial arrhythmia (HP:0001692)1.69973915
171Duplication of thumb phalanx (HP:0009942)1.69875422

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK3.53945873
2MKNK23.09979354
3STK162.73865494
4MKNK12.70160700
5TRIM282.61022370
6WNK32.55632148
7MAP4K22.42688718
8BRSK22.41932729
9BUB12.35508857
10VRK12.34870044
11GRK12.31050597
12ZAK2.27040879
13SRPK12.26492572
14WEE12.06365362
15STK242.02011476
16EIF2AK11.92378444
17NME21.83991960
18OBSCN1.78566226
19CDK81.78073443
20ACVR1B1.71811969
21MAP3K41.70944357
22MAPK131.59465636
23CASK1.59044071
24MAP2K71.56623291
25GRK71.51770339
26VRK21.49588839
27TAOK31.46315706
28MST41.45551103
29EIF2AK31.44576786
30CDC71.43069259
31AKT31.40865032
32WNK41.40759147
33MAP3K121.38707256
34MAP2K61.38546973
35EIF2AK21.34074613
36TXK1.34052660
37NME11.31036590
38TLK11.28839662
39FLT31.26522371
40IRAK31.23277077
41BRD41.20797553
42TGFBR11.19846513
43RPS6KA41.19359414
44NLK1.18086101
45PNCK1.16750996
46CDK31.16706578
47PLK31.15004277
48DYRK21.13810340
49CLK11.13492933
50MAP2K31.13310838
51ATR1.09220557
52STK38L1.07810017
53STK41.05946916
54MYLK1.05741540
55BRAF1.05127119
56BRSK11.03850068
57NEK21.03603677
58EPHA21.03566871
59MUSK1.03432530
60INSRR1.01714921
61TEC1.01281104
62YES11.01249327
63ADRBK21.00525762
64OXSR10.99584027
65STK390.95295880
66PASK0.94763716
67PAK30.94033127
68CSNK1G10.91494047
69MARK10.90668437
70PLK40.89899213
71NEK10.88440376
72TTK0.88395415
73CCNB10.87284330
74BCKDK0.84196785
75AURKA0.84046623
76CSNK1G30.83759458
77NEK60.83646107
78PLK10.83521862
79MAPKAPK30.81892650
80MAP3K140.79834990
81PRKCG0.79620560
82DAPK20.79472060
83CSNK1G20.79451813
84AURKB0.77900173
85TSSK60.77711013
86CHEK20.77560301
87RPS6KB20.76999105
88BMPR1B0.76256578
89PRKCE0.74703478
90RPS6KA50.70616877
91IRAK40.70473224
92TAF10.69296204
93CSNK1A1L0.69225612
94TAOK20.68716864
95PLK20.65469706
96CAMKK20.64137063
97STK30.62886483
98MAP3K60.62329988
99LMTK20.62191010
100CDK70.58042279
101CSNK2A10.57199173
102PHKG20.56285483
103PHKG10.56285483
104FGFR20.56057376
105DYRK30.55725103
106PAK60.54468511
107EPHA40.52397557
108PINK10.51213870
109MAP3K130.51006509
110NUAK10.50846249
111TRPM70.49645310
112STK100.49406075
113PIK3CA0.47159572
114TIE10.46818127
115MARK30.46553408
116BCR0.46215415
117FRK0.45628322
118MAPK70.42149971
119CSNK1A10.41963671
120MINK10.41037957
121ERBB30.40964523
122CSNK2A20.39995464
123NTRK30.39372735
124ADRBK10.38001579
125PRKCI0.37612661
126ATM0.37130833
127MAP2K40.36976295
128CHEK10.36749182
129CAMK2A0.36622057
130SGK20.36411893
131PBK0.36013539
132PRPF4B0.35619245
133AKT20.35568830
134PIM20.35079667
135PKN20.34272729
136SIK30.34132557
137CSNK1D0.33763156
138MAPK150.33555114
139PKN10.33166404
140MAPKAPK50.32656321
141CDK190.32481634
142PRKCQ0.32293265
143MAPK120.30619832
144IKBKB0.29947767

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.15687319
2DNA replication_Homo sapiens_hsa030303.95955988
3Mismatch repair_Homo sapiens_hsa034303.62442039
4RNA polymerase_Homo sapiens_hsa030203.48303775
5Oxidative phosphorylation_Homo sapiens_hsa001903.29568819
6Proteasome_Homo sapiens_hsa030503.24719314
7Parkinsons disease_Homo sapiens_hsa050123.04538087
8Base excision repair_Homo sapiens_hsa034102.74893202
9Nucleotide excision repair_Homo sapiens_hsa034202.74659265
10Huntingtons disease_Homo sapiens_hsa050162.56504571
11Spliceosome_Homo sapiens_hsa030402.54866242
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.54552840
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.48991162
14Homologous recombination_Homo sapiens_hsa034402.46921378
15Fanconi anemia pathway_Homo sapiens_hsa034602.42859138
16Pyrimidine metabolism_Homo sapiens_hsa002402.36625334
17Alzheimers disease_Homo sapiens_hsa050102.20635669
18Cardiac muscle contraction_Homo sapiens_hsa042602.11331814
19Butanoate metabolism_Homo sapiens_hsa006502.06876889
20One carbon pool by folate_Homo sapiens_hsa006701.98247895
21Basal transcription factors_Homo sapiens_hsa030221.92867101
22Nitrogen metabolism_Homo sapiens_hsa009101.89800235
23RNA transport_Homo sapiens_hsa030131.84405484
24* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.82612282
25Non-homologous end-joining_Homo sapiens_hsa034501.81502986
26RNA degradation_Homo sapiens_hsa030181.77254565
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.74624897
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.70847836
29Linoleic acid metabolism_Homo sapiens_hsa005911.65681584
30Cell cycle_Homo sapiens_hsa041101.65436529
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.63175336
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.60536724
33* Selenocompound metabolism_Homo sapiens_hsa004501.59985734
34Purine metabolism_Homo sapiens_hsa002301.58961089
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.49314949
36Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.45399730
37Ether lipid metabolism_Homo sapiens_hsa005651.43841970
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.43365955
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.37649416
40Peroxisome_Homo sapiens_hsa041461.28355999
41Tryptophan metabolism_Homo sapiens_hsa003801.25525807
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.24813992
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.22916177
44Taste transduction_Homo sapiens_hsa047421.15623692
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.11210695
46Primary immunodeficiency_Homo sapiens_hsa053401.07921479
47Sulfur metabolism_Homo sapiens_hsa009201.07074018
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.94648617
49Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.93210863
50Primary bile acid biosynthesis_Homo sapiens_hsa001200.91512406
51Steroid biosynthesis_Homo sapiens_hsa001000.90936218
52Caffeine metabolism_Homo sapiens_hsa002320.88026053
53Olfactory transduction_Homo sapiens_hsa047400.87290093
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86307003
55p53 signaling pathway_Homo sapiens_hsa041150.86196156
56Sulfur relay system_Homo sapiens_hsa041220.85048866
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83976970
58Propanoate metabolism_Homo sapiens_hsa006400.82752814
59Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79451838
60Protein export_Homo sapiens_hsa030600.77795326
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.76416607
62beta-Alanine metabolism_Homo sapiens_hsa004100.76286295
63Epstein-Barr virus infection_Homo sapiens_hsa051690.76267433
64mRNA surveillance pathway_Homo sapiens_hsa030150.74342492
65Systemic lupus erythematosus_Homo sapiens_hsa053220.73489543
66Morphine addiction_Homo sapiens_hsa050320.72245402
67Chemical carcinogenesis_Homo sapiens_hsa052040.72225417
68Pyruvate metabolism_Homo sapiens_hsa006200.70560771
69Herpes simplex infection_Homo sapiens_hsa051680.70386716
70Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.70073495
71Arachidonic acid metabolism_Homo sapiens_hsa005900.69900584
72Fat digestion and absorption_Homo sapiens_hsa049750.66956000
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66653327
74Collecting duct acid secretion_Homo sapiens_hsa049660.65509493
75Dilated cardiomyopathy_Homo sapiens_hsa054140.64587931
76Nicotine addiction_Homo sapiens_hsa050330.61698929
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61402384
78Hematopoietic cell lineage_Homo sapiens_hsa046400.59227941
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59177634
80Fructose and mannose metabolism_Homo sapiens_hsa000510.58021675
81Metabolic pathways_Homo sapiens_hsa011000.57533944
82GABAergic synapse_Homo sapiens_hsa047270.55745363
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54993584
84Carbon metabolism_Homo sapiens_hsa012000.54959365
85Galactose metabolism_Homo sapiens_hsa000520.53835452
86Graft-versus-host disease_Homo sapiens_hsa053320.53286737
87Steroid hormone biosynthesis_Homo sapiens_hsa001400.51999097
88ABC transporters_Homo sapiens_hsa020100.51767193
89Calcium signaling pathway_Homo sapiens_hsa040200.50512093
90Retinol metabolism_Homo sapiens_hsa008300.50120536
91Insulin secretion_Homo sapiens_hsa049110.49912202
92Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.49878192
93SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49594537
94Fatty acid metabolism_Homo sapiens_hsa012120.49413131
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46316293
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.46309165
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46212272
98Fatty acid degradation_Homo sapiens_hsa000710.44148067
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42024413
100Dopaminergic synapse_Homo sapiens_hsa047280.41748740
101Vitamin B6 metabolism_Homo sapiens_hsa007500.38800482
102Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38164537
103Glutamatergic synapse_Homo sapiens_hsa047240.37857465
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36292436
105Phototransduction_Homo sapiens_hsa047440.36116847
106Fatty acid elongation_Homo sapiens_hsa000620.35356858
107Glycerolipid metabolism_Homo sapiens_hsa005610.35229356
108Glutathione metabolism_Homo sapiens_hsa004800.35071306
109Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34014933
110Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34004025
111Oocyte meiosis_Homo sapiens_hsa041140.33693952
112Folate biosynthesis_Homo sapiens_hsa007900.32378476
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30461189
114HTLV-I infection_Homo sapiens_hsa051660.30290186
115Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.27913701
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26732835
117Autoimmune thyroid disease_Homo sapiens_hsa053200.25895036
118HIF-1 signaling pathway_Homo sapiens_hsa040660.24914551
119Biosynthesis of amino acids_Homo sapiens_hsa012300.24853135
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.22412076
1212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.21471894
122Regulation of autophagy_Homo sapiens_hsa041400.20777303
123Legionellosis_Homo sapiens_hsa051340.19634010
124Antigen processing and presentation_Homo sapiens_hsa046120.19302846
125Hepatitis B_Homo sapiens_hsa051610.19140698
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.18995610
127Thyroid cancer_Homo sapiens_hsa052160.18319244
128Measles_Homo sapiens_hsa051620.17981902
129Allograft rejection_Homo sapiens_hsa053300.17767665
130Circadian entrainment_Homo sapiens_hsa047130.16012152
131Alcoholism_Homo sapiens_hsa050340.15881612
132Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.15787787
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.15695407
134Influenza A_Homo sapiens_hsa051640.14736864
135Viral carcinogenesis_Homo sapiens_hsa052030.14335848
136NF-kappa B signaling pathway_Homo sapiens_hsa040640.13424653
137Circadian rhythm_Homo sapiens_hsa047100.11848371
138Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.10848523
139Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.10562830
140Serotonergic synapse_Homo sapiens_hsa047260.09480993
141Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08923549
142Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.08638140
143Basal cell carcinoma_Homo sapiens_hsa052170.08525957
144Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.08370974
145Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.05991403

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »