PSTPIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to peptidoglycan (GO:0032494)5.68092736
2positive regulation by symbiont of host defense response (GO:0052509)5.11477378
3modulation by symbiont of host defense response (GO:0052031)5.11477378
4modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.11477378
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.11477378
6positive regulation by organism of defense response of other organism involved in symbiotic interact5.11477378
7modulation by symbiont of host immune response (GO:0052553)5.11477378
8respiratory burst (GO:0045730)4.93356263
9neutrophil activation involved in immune response (GO:0002283)4.91522065
10hydrogen peroxide biosynthetic process (GO:0050665)4.81873421
11reactive oxygen species biosynthetic process (GO:1903409)4.46312128
12production of molecular mediator involved in inflammatory response (GO:0002532)3.98705190
13positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.91228861
14positive regulation of chemokine biosynthetic process (GO:0045080)3.88523421
15response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.81145243
16response to host immune response (GO:0052572)3.81145243
17regulation of T-helper 1 cell differentiation (GO:0045625)3.80602612
18macrophage activation involved in immune response (GO:0002281)3.76897838
19negative regulation of cell killing (GO:0031342)3.71943355
20negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.71943355
21superoxide anion generation (GO:0042554)3.71370786
22positive regulation of interferon-alpha production (GO:0032727)3.67685975
23granulocyte activation (GO:0036230)3.65882193
24low-density lipoprotein particle clearance (GO:0034383)3.64757004
25leukocyte aggregation (GO:0070486)3.64311775
26regulation of vitamin D biosynthetic process (GO:0060556)3.63837329
27immunoglobulin mediated immune response (GO:0016064)3.59249800
28lipopolysaccharide-mediated signaling pathway (GO:0031663)3.54949366
29positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.53561182
30response to fungus (GO:0009620)3.50293949
31regulation of interferon-alpha production (GO:0032647)3.48121621
32killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.46508836
33disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.46508836
34neutrophil activation (GO:0042119)3.45276607
35regulation of interferon-beta biosynthetic process (GO:0045357)3.42443834
36detection of other organism (GO:0098543)3.40576154
37regulation of gamma-delta T cell activation (GO:0046643)3.36441351
38response to host defenses (GO:0052200)3.35919318
39response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.35919318
40response to host (GO:0075136)3.35919318
41cellular extravasation (GO:0045123)3.34491649
42response to muramyl dipeptide (GO:0032495)3.34304473
43B cell mediated immunity (GO:0019724)3.33010719
44positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.31620477
45positive regulation of B cell differentiation (GO:0045579)3.28706179
46positive regulation of cellular amide metabolic process (GO:0034250)3.28279997
47response to protozoan (GO:0001562)3.27091401
48negative regulation of erythrocyte differentiation (GO:0045647)3.24715515
49regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.22970516
50germinal center formation (GO:0002467)3.22482502
51positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.22005527
52defense response to protozoan (GO:0042832)3.21262949
53detection of bacterium (GO:0016045)3.20092212
54leukocyte migration involved in inflammatory response (GO:0002523)3.17870381
55positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.17803209
56regulation of chemokine biosynthetic process (GO:0045073)3.16822207
57interferon-gamma-mediated signaling pathway (GO:0060333)3.15238674
58positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.10915124
59antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.10875770
60regulation of platelet activation (GO:0010543)3.08479537
61negative regulation of cytokine production involved in immune response (GO:0002719)3.07438384
62regulation of B cell receptor signaling pathway (GO:0050855)3.04185633
63myeloid cell activation involved in immune response (GO:0002275)3.04148373
64plasma lipoprotein particle clearance (GO:0034381)3.02669873
65disruption of cells of other organism (GO:0044364)3.02415471
66killing of cells of other organism (GO:0031640)3.02415471
67leukocyte degranulation (GO:0043299)3.01034308
68positive regulation of toll-like receptor signaling pathway (GO:0034123)3.00625172
69thrombin receptor signaling pathway (GO:0070493)3.00267454
70neutrophil mediated immunity (GO:0002446)2.97864145
71negative regulation of T cell mediated immunity (GO:0002710)2.97457716
72phagosome maturation (GO:0090382)2.97157881
73positive regulation of type 2 immune response (GO:0002830)2.97049274
74negative regulation of interleukin-12 production (GO:0032695)2.95785483
75T-helper 1 type immune response (GO:0042088)2.94987724
76negative regulation of myeloid cell apoptotic process (GO:0033033)2.94306746
77negative regulation of growth of symbiont in host (GO:0044130)2.94082924
78negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.94082924
79modulation of growth of symbiont involved in interaction with host (GO:0044144)2.94082924
80regulation of growth of symbiont in host (GO:0044126)2.94082924
81regulation of podosome assembly (GO:0071801)2.93435097
82regulation of interleukin-12 production (GO:0032655)2.92302778
83cellular response to thyroid hormone stimulus (GO:0097067)2.88890458
84detection of molecule of bacterial origin (GO:0032490)2.84797887
85regulation of integrin activation (GO:0033623)2.84671913
86neutrophil chemotaxis (GO:0030593)2.82806904
87regulation of vitamin metabolic process (GO:0030656)2.82231141
88defense response to fungus (GO:0050832)2.82115136
89regulation of dendritic cell antigen processing and presentation (GO:0002604)2.81656730
90T cell migration (GO:0072678)2.80605154
91regulation of mast cell degranulation (GO:0043304)2.80211576
92positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.79511672
93regulation of interleukin-8 biosynthetic process (GO:0045414)2.78560184
94positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.78402468
95regulation of T-helper 2 cell differentiation (GO:0045628)2.77890431
96negative regulation of interleukin-17 production (GO:0032700)2.77848565
97positive regulation of interleukin-10 production (GO:0032733)2.77553415
98detection of external biotic stimulus (GO:0098581)2.76742052
99regulation of chronic inflammatory response (GO:0002676)2.76034828
100positive regulation of mast cell activation involved in immune response (GO:0033008)2.75049097
101positive regulation of mast cell degranulation (GO:0043306)2.75049097
102positive regulation of antigen processing and presentation (GO:0002579)2.74822419
103neutrophil migration (GO:1990266)2.74227721
104positive regulation of interleukin-6 production (GO:0032755)2.74085291
105regulation of platelet aggregation (GO:0090330)2.73530176
106regulation of interleukin-17 production (GO:0032660)2.73443759
107positive regulation of mast cell activation (GO:0033005)2.72820844
108myeloid leukocyte activation (GO:0002274)2.71720746
109regulation of antigen processing and presentation (GO:0002577)2.71036338
110positive regulation of interleukin-17 production (GO:0032740)2.71007880
111positive regulation of B cell mediated immunity (GO:0002714)2.70845897
112activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.70719040
113positive regulation of interferon-beta production (GO:0032728)2.66843132
114regulation of mast cell activation (GO:0033003)2.64316748
115antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.63929078
116antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.63929078
117antigen processing and presentation of endogenous antigen (GO:0019883)2.63188220
118regulation of heterotypic cell-cell adhesion (GO:0034114)2.63007795
119regulation of triglyceride catabolic process (GO:0010896)2.62947293
120regulation of mast cell activation involved in immune response (GO:0033006)2.60887329
121leukocyte mediated cytotoxicity (GO:0001909)2.60632933
122natural killer cell mediated immunity (GO:0002228)2.60468058
123natural killer cell mediated cytotoxicity (GO:0042267)2.60468058
124positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.59411342
125cellular response to type I interferon (GO:0071357)2.58552736
126type I interferon signaling pathway (GO:0060337)2.58552736
127regulation of mononuclear cell migration (GO:0071675)2.58257704
128cell killing (GO:0001906)2.58041664
129response to type I interferon (GO:0034340)2.56985365
130microglial cell activation (GO:0001774)2.56290030
131negative regulation of mast cell activation (GO:0033004)2.55616795
132cofactor catabolic process (GO:0051187)2.54215356
133regulation of leukocyte degranulation (GO:0043300)2.54166962
134macrophage activation (GO:0042116)2.53205664
135positive regulation of gamma-delta T cell activation (GO:0046645)2.52935213
136regulation of myeloid leukocyte mediated immunity (GO:0002886)2.52674768
137positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.52551943
138positive regulation of leukocyte degranulation (GO:0043302)2.51807617
139leukotriene metabolic process (GO:0006691)2.50982341
140regulation of membrane protein ectodomain proteolysis (GO:0051043)2.49532552
141skeletal muscle adaptation (GO:0043501)2.49309296

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human7.17243229
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.87791091
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.55490145
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.85327296
5ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.77717762
6IRF8_27001747_Chip-Seq_BMDM_Mouse3.73290783
7SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.48719914
8Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.39966798
9* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.16570735
10* MYB_21317192_ChIP-Seq_ERMYB_Mouse3.02888463
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.90518784
12RXR_22158963_ChIP-Seq_LIVER_Mouse2.77870285
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.68130828
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.66320944
15PPARA_22158963_ChIP-Seq_LIVER_Mouse2.57011313
16LXR_22158963_ChIP-Seq_LIVER_Mouse2.47339106
17EGR1_23403033_ChIP-Seq_LIVER_Mouse2.33794061
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.17777220
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.08465489
20BRD4_27068464_Chip-Seq_AML-cells_Mouse2.05548942
21FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.99683584
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.97112093
23PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.89615442
24FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.81417013
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.79095039
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.77935472
27SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.75537358
28STAT4_19710469_ChIP-ChIP_TH1__Mouse1.74447576
29NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.73883987
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73583860
31STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.69905272
32* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.69447732
33CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.60897594
34CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.55137093
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.54364428
36SPI1_23547873_ChIP-Seq_NB4_Human1.51189945
37RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.50813325
38TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.49719584
39PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.46620344
40SPI1_23127762_ChIP-Seq_K562_Human1.46076776
41VDR_24787735_ChIP-Seq_THP-1_Human1.43290212
42CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.41388466
43NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.40330398
44CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39005390
45* PU_27001747_Chip-Seq_BMDM_Mouse1.38879355
46VDR_24763502_ChIP-Seq_THP-1_Human1.37464603
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.30735565
48* RUNX1_22412390_ChIP-Seq_EML_Mouse1.29542260
49CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.28964279
50CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26841697
51EGR1_19374776_ChIP-ChIP_THP-1_Human1.25313723
52CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.23701728
53ELF1_17652178_ChIP-ChIP_JURKAT_Human1.23598360
54MYC_22102868_ChIP-Seq_BL_Human1.21385562
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21265070
56EGR1_19032775_ChIP-ChIP_M12_Human1.21150488
57NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.20756364
58MAF_26560356_Chip-Seq_TH1_Human1.19522692
59SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.18691903
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18076290
61LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17430343
62CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.17097083
63GATA2_21666600_ChIP-Seq_HMVEC_Human1.15676203
64LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.15637871
65NRF2_20460467_ChIP-Seq_MEFs_Mouse1.15555354
66NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.15555354
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15386818
68PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15195853
69MYB_26560356_Chip-Seq_TH2_Human1.12370680
70MAF_26560356_Chip-Seq_TH2_Human1.11282320
71SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10898354
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10730891
73PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10553947
74PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09656303
75TCF7_22412390_ChIP-Seq_EML_Mouse1.09077496
76RUNX_20019798_ChIP-Seq_JUKART_Human1.07531197
77SCL_19346495_ChIP-Seq_HPC-7_Human1.06548137
78GATA3_26560356_Chip-Seq_TH2_Human1.06235043
79NCOR1_26117541_ChIP-Seq_K562_Human1.04651013
80GATA2_19941826_ChIP-Seq_K562_Human1.04265912
81GATA1_19941826_ChIP-Seq_K562_Human1.04102412
82* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02820956
83STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00584826
84* GATA1_19941827_ChIP-Seq_MEL_Mouse1.00153229
85VDR_21846776_ChIP-Seq_THP-1_Human0.99315367
86GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.99223010
87STAT1_20625510_ChIP-Seq_HELA_Human0.97697357
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96746370
89SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96607191
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.95589417
91HOXB4_20404135_ChIP-ChIP_EML_Mouse0.95247394
92BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94592855
93GATA3_27048872_Chip-Seq_THYMUS_Human0.94484752
94* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.93507790
95TFEB_21752829_ChIP-Seq_HELA_Human0.93481229
96FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.92979004
97GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90522620
98E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.89934264
99* SOX2_20726797_ChIP-Seq_SW620_Human0.89074677
100GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85040050
101* ESR2_21235772_ChIP-Seq_MCF-7_Human0.85021055
102VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.84721194
103SOX2_27498859_Chip-Seq_STOMACH_Mouse0.84611022
104MYB_26560356_Chip-Seq_TH1_Human0.84571419
105GATA1_22025678_ChIP-Seq_K562_Human0.83743211
106KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.83616727
107RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82628223
108KDM2B_26808549_Chip-Seq_SUP-B15_Human0.82363260
109PU.1_20513432_ChIP-Seq_Bcells_Mouse0.78363214
110UTX_26944678_Chip-Seq_JUKART_Human0.77820340
111P63_26484246_Chip-Seq_KERATINOCYTES_Human0.77409412
112SPI1_20517297_ChIP-Seq_HL60_Human0.77124293
113GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77045528
114TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76871192
115BCL6_27268052_Chip-Seq_Bcells_Human0.76737164
116ESR1_20079471_ChIP-ChIP_T-47D_Human0.76356487
117RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73948961
118ETS1_22383799_ChIP-Seq_G1ME_Mouse0.72307030
119KDM2B_26808549_Chip-Seq_DND41_Human0.71320512
120GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70590189
121JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.70445533
122* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69507651
123BCOR_27268052_Chip-Seq_Bcells_Human0.69240036
124TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.69201338
125MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.68570526
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67062379
127ELK3_25401928_ChIP-Seq_HUVEC_Human0.66034305
128FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.65829309

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003436_decreased_susceptibility_to3.86340493
2MP0003303_peritoneal_inflammation3.53532739
3MP0009785_altered_susceptibility_to3.40860894
4MP0001835_abnormal_antigen_presentation3.06285570
5MP0002419_abnormal_innate_immunity3.00463389
6MP0005360_urolithiasis2.83173506
7MP0002148_abnormal_hypersensitivity_rea2.79322946
8MP0009840_abnormal_foam_cell2.76793575
9MP0006082_CNS_inflammation2.69463884
10MP0005025_abnormal_response_to2.63899317
11* MP0005000_abnormal_immune_tolerance2.57126214
12MP0002139_abnormal_hepatobiliary_system2.53496305
13MP0003724_increased_susceptibility_to2.52472585
14MP0005058_abnormal_lysosome_morphology2.42658111
15MP0004510_myositis2.36204469
16MP0003806_abnormal_nucleotide_metabolis2.23026023
17MP0005387_immune_system_phenotype2.22658914
18MP0001790_abnormal_immune_system2.22658914
19MP0008004_abnormal_stomach_pH2.22411075
20* MP0001533_abnormal_skeleton_physiology2.01476589
21MP0003646_muscle_fatigue2.01170661
22MP0009278_abnormal_bone_marrow1.98341536
23MP0000685_abnormal_immune_system1.97975180
24* MP0002452_abnormal_antigen_presenting1.93091309
25MP0005464_abnormal_platelet_physiology1.91588537
26* MP0002723_abnormal_immune_serum1.85240559
27MP0009764_decreased_sensitivity_to1.85199238
28* MP0001800_abnormal_humoral_immune1.84667436
29MP0001853_heart_inflammation1.83431935
30MP0003191_abnormal_cellular_cholesterol1.83279391
31MP0000343_altered_response_to1.80645630
32MP0003075_altered_response_to1.79399355
33MP0003172_abnormal_lysosome_physiology1.76323249
34MP0003656_abnormal_erythrocyte_physiolo1.75125947
35MP0005085_abnormal_gallbladder_physiolo1.74743017
36MP0008469_abnormal_protein_level1.74272508
37* MP0004947_skin_inflammation1.73941524
38MP0003195_calcinosis1.73521865
39MP0003183_abnormal_peptide_metabolism1.71741784
40* MP0001845_abnormal_inflammatory_respons1.70809489
41MP0000604_amyloidosis1.62563947
42MP0005083_abnormal_biliary_tract1.62118728
43* MP0001819_abnormal_immune_cell1.60466591
44MP0000465_gastrointestinal_hemorrhage1.59711055
45MP0005451_abnormal_body_composition1.58103964
46* MP0002420_abnormal_adaptive_immunity1.57950255
47MP0005365_abnormal_bile_salt1.57688606
48MP0003186_abnormal_redox_activity1.57073489
49MP0005671_abnormal_response_to1.53322780
50MP0008875_abnormal_xenobiotic_pharmacok1.49065052
51MP0002405_respiratory_system_inflammati1.47758661
52MP0008260_abnormal_autophagy1.37973177
53MP0010155_abnormal_intestine_physiology1.36188472
54MP0003763_abnormal_thymus_physiology1.33266460
55MP0006054_spinal_hemorrhage1.29662367
56MP0010329_abnormal_lipoprotein_level1.24246867
57MP0005167_abnormal_blood-brain_barrier1.23805478
58MP0005166_decreased_susceptibility_to1.23682917
59MP0005310_abnormal_salivary_gland1.23329229
60MP0003252_abnormal_bile_duct1.22141283
61MP0001851_eye_inflammation1.21942400
62MP0003300_gastrointestinal_ulcer1.20147841
63MP0000609_abnormal_liver_physiology1.19490750
64MP0003690_abnormal_glial_cell1.18721890
65MP0009763_increased_sensitivity_to1.17989694
66MP0000920_abnormal_myelination1.17553684
67MP0003448_altered_tumor_morphology1.16947291
68MP0001545_abnormal_hematopoietic_system1.11584890
69MP0005397_hematopoietic_system_phenotyp1.11584890
70MP0005319_abnormal_enzyme/_coenzyme1.11152939
71MP0004808_abnormal_hematopoietic_stem1.11122566
72MP0000716_abnormal_immune_system1.07662265
73MP0004130_abnormal_muscle_cell1.07599451
74MP0002998_abnormal_bone_remodeling1.05688178
75MP0009333_abnormal_splenocyte_physiolog1.05500852
76MP0005584_abnormal_enzyme/coenzyme_acti1.04768770
77MP0002118_abnormal_lipid_homeostasis1.00060689
78MP0001663_abnormal_digestive_system0.99890429
79MP0002132_abnormal_respiratory_system0.93969904
80MP0001666_abnormal_nutrient_absorption0.93861283
81MP0003453_abnormal_keratinocyte_physiol0.90422426
82MP0000858_altered_metastatic_potential0.88202600
83MP0000749_muscle_degeneration0.87581455
84MP0005332_abnormal_amino_acid0.86271513
85MP0003329_amyloid_beta_deposits0.86144830
86MP0002933_joint_inflammation0.85826326
87MP0005164_abnormal_response_to0.85585372
88MP0004883_abnormal_blood_vessel0.84904068
89MP0002398_abnormal_bone_marrow0.84829940
90MP0002837_dystrophic_cardiac_calcinosis0.83618628
91MP0000703_abnormal_thymus_morphology0.82176756
92* MP0002429_abnormal_blood_cell0.81853008
93MP0003221_abnormal_cardiomyocyte_apopto0.81498792
94MP0002006_tumorigenesis0.81040974
95* MP0005390_skeleton_phenotype0.78340347
96MP0003828_pulmonary_edema0.78170561
97MP0002396_abnormal_hematopoietic_system0.78121684
98MP0003566_abnormal_cell_adhesion0.78053960
99* MP0000689_abnormal_spleen_morphology0.77261007
100MP0008874_decreased_physiological_sensi0.75832548
101MP0005165_increased_susceptibility_to0.75813059
102MP0003866_abnormal_defecation0.75079014
103MP0002138_abnormal_hepatobiliary_system0.74911945
104MP0005535_abnormal_body_temperature0.72305941
105MP0009643_abnormal_urine_homeostasis0.70216352
106MP0002254_reproductive_system_inflammat0.70113519
107MP0000249_abnormal_blood_vessel0.67772443
108MP0002332_abnormal_exercise_endurance0.67187303
109MP0003795_abnormal_bone_structure0.66770710
110MP0000015_abnormal_ear_pigmentation0.65430664
111* MP0002722_abnormal_immune_system0.65320638
112MP0005076_abnormal_cell_differentiation0.64719386
113MP0001873_stomach_inflammation0.64657353
114MP0009765_abnormal_xenobiotic_induced0.64593076
115MP0001764_abnormal_homeostasis0.64550988
116MP0004858_abnormal_nervous_system0.64467199
117MP0002106_abnormal_muscle_physiology0.63838531
118MP0005647_abnormal_sex_gland0.55345306
119MP0002277_abnormal_respiratory_mucosa0.54976246
120MP0005381_digestive/alimentary_phenotyp0.54681653
121MP0003091_abnormal_cell_migration0.52741580
122MP0003045_fibrosis0.52691402
123MP0002019_abnormal_tumor_incidence0.52646928
124MP0005023_abnormal_wound_healing0.50028771
125MP0002877_abnormal_melanocyte_morpholog0.49718724

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)7.00012039
2Recurrent abscess formation (HP:0002722)6.74732989
3Recurrent gram-negative bacterial infections (HP:0005420)6.67336826
4Recurrent bacterial skin infections (HP:0005406)6.19633605
5Prolonged bleeding time (HP:0003010)5.24549214
6Abnormality of macrophages (HP:0004311)4.90236146
7Systemic lupus erythematosus (HP:0002725)4.28169047
8Epistaxis (HP:0000421)4.03984017
9Mediastinal lymphadenopathy (HP:0100721)4.03435241
10Gingivitis (HP:0000230)3.96065610
11Orchitis (HP:0100796)3.94905547
12Retrobulbar optic neuritis (HP:0100654)3.82711578
13Optic neuritis (HP:0100653)3.82711578
14Elevated erythrocyte sedimentation rate (HP:0003565)3.74956610
15Recurrent skin infections (HP:0001581)3.64536208
16Abnormal platelet volume (HP:0011876)3.63736862
17Axonal loss (HP:0003447)3.62656292
18Myositis (HP:0100614)3.58905270
19Stomatitis (HP:0010280)3.56325490
20Chronic obstructive pulmonary disease (HP:0006510)3.50622301
21Obstructive lung disease (HP:0006536)3.50622301
22Increased mean platelet volume (HP:0011877)3.44844493
23Spontaneous hematomas (HP:0007420)3.38389189
24Menorrhagia (HP:0000132)3.10153118
25Vacuolated lymphocytes (HP:0001922)3.09982015
26Encephalitis (HP:0002383)3.08294577
27Autoimmune thrombocytopenia (HP:0001973)3.07702576
28Urticaria (HP:0001025)3.06537441
29Increased IgM level (HP:0003496)2.99059959
30Increased cerebral lipofuscin (HP:0011813)2.93063410
31Recurrent fungal infections (HP:0002841)2.88536708
32Impaired platelet aggregation (HP:0003540)2.88121814
33Abnormal platelet function (HP:0011869)2.88121814
34Autoimmune hemolytic anemia (HP:0001890)2.85284131
35Vasculitis (HP:0002633)2.85099724
36Muscle fiber inclusion bodies (HP:0100299)2.82663081
37Increased neuronal autofluorescent lipopigment (HP:0002074)2.78631617
38Joint hemorrhage (HP:0005261)2.78157941
39Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.74495762
40Amyloidosis (HP:0011034)2.74300427
41Xanthomatosis (HP:0000991)2.72118036
42Hemoptysis (HP:0002105)2.71678551
43T lymphocytopenia (HP:0005403)2.71639553
44Cellulitis (HP:0100658)2.70397940
45Glomerulonephritis (HP:0000099)2.67911655
46Disinhibition (HP:0000734)2.65915112
47Nemaline bodies (HP:0003798)2.65387688
48Abnormality of T cell number (HP:0011839)2.63838504
49Gastrointestinal infarctions (HP:0005244)2.63716670
50Chronic mucocutaneous candidiasis (HP:0002728)2.61694770
51Recurrent cutaneous fungal infections (HP:0011370)2.61694770
52Abnormality of the vasculature of the conjunctiva (HP:0008054)2.59711978
53Abnormal delayed hypersensitivity skin test (HP:0002963)2.56936422
54Chest pain (HP:0100749)2.55570402
55Peritonitis (HP:0002586)2.54224843
56Myocardial infarction (HP:0001658)2.52632244
57Keratoconjunctivitis sicca (HP:0001097)2.50034477
58Episodic fever (HP:0001954)2.46923335
59Abnormality of the heme biosynthetic pathway (HP:0010472)2.44501596
60Ulnar deviation of the wrist (HP:0003049)2.42182412
61Gingival bleeding (HP:0000225)2.42153731
62Exercise-induced muscle cramps (HP:0003710)2.41391057
63Vertigo (HP:0002321)2.40570304
64Keratoconjunctivitis (HP:0001096)2.36096180
65Periodontitis (HP:0000704)2.35424313
66Pulmonary infiltrates (HP:0002113)2.34263162
67Meningitis (HP:0001287)2.31919375
68Joint swelling (HP:0001386)2.31337744
69Deep venous thrombosis (HP:0002625)2.29730997
70Thick nail (HP:0001805)2.29285909
71Abnormality of the common coagulation pathway (HP:0010990)2.28297040
72Hepatosplenomegaly (HP:0001433)2.28106319
73Polyneuropathy (HP:0001271)2.27603105
74Tetraparesis (HP:0002273)2.25976152
75Recurrent viral infections (HP:0004429)2.25899358
76Granulocytopenia (HP:0001913)2.22416708
77Pustule (HP:0200039)2.21625348
78Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.20158689
79Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.19685498
80Osteomyelitis (HP:0002754)2.19681505
81Abnormality of T cells (HP:0002843)2.18069491
82Abnormality of complement system (HP:0005339)2.17990507
83Paralysis (HP:0003470)2.17863212
84Increased IgE level (HP:0003212)2.17746945
85Complement deficiency (HP:0004431)2.17431072
86Abnormality of aromatic amino acid family metabolism (HP:0004338)2.16465856
87Nephritis (HP:0000123)2.16042611
88Amaurosis fugax (HP:0100576)2.14579715
89Abnormality of glycolipid metabolism (HP:0010969)2.14263358
90Abnormality of liposaccharide metabolism (HP:0010968)2.14263358
91Abnormality of glycosphingolipid metabolism (HP:0004343)2.14263358
92Hypergammaglobulinemia (HP:0010702)2.14074809
93Basal ganglia calcification (HP:0002135)2.14000050
94Intrahepatic cholestasis (HP:0001406)2.12259514
95Recurrent pneumonia (HP:0006532)2.11685363
96Increased serum ferritin (HP:0003281)2.10056592
97Abnormality of glutamine family amino acid metabolism (HP:0010902)2.09629261
98Inflammation of the large intestine (HP:0002037)2.09440305
99Hypoglycemic coma (HP:0001325)2.08770221
100Exercise-induced myalgia (HP:0003738)2.08286585
101Arterial thrombosis (HP:0004420)2.07058609
102Mutism (HP:0002300)2.05579527
103Conjunctival telangiectasia (HP:0000524)2.05478188
104Prolonged partial thromboplastin time (HP:0003645)2.05293523
105Thrombocytosis (HP:0001894)2.04839445
106Abnormality of the prostate (HP:0008775)2.04595324
107Abnormality of iron homeostasis (HP:0011031)2.02929332
108Nausea (HP:0002018)2.02551605
109Thrombophlebitis (HP:0004418)2.02278438
110Leukocytosis (HP:0001974)2.02101822
111Muscle fiber splitting (HP:0003555)2.01960198
112Mucopolysacchariduria (HP:0008155)2.01874062
113Urinary glycosaminoglycan excretion (HP:0003541)2.01874062
114Abnormality of monocarboxylic acid metabolism (HP:0010996)2.00529398
115Dysostosis multiplex (HP:0000943)2.00440596
116Purpura (HP:0000979)1.99920158
117Petechiae (HP:0000967)1.99826001
118Panhypogammaglobulinemia (HP:0003139)1.99152308
119Eosinophilia (HP:0001880)1.97563016
120Glomerulopathy (HP:0100820)1.96724570
121Hematochezia (HP:0002573)1.96282578
122Interstitial pulmonary disease (HP:0006530)1.95863871
123Hemorrhage of the eye (HP:0011885)1.95403491
124Polycythemia (HP:0001901)1.94934373
125Gastrointestinal inflammation (HP:0004386)1.94776457
126Abnormality of the pleura (HP:0002103)1.94607349
127Hypobetalipoproteinemia (HP:0003563)1.94503325
128Loss of speech (HP:0002371)1.94335550
129Chronic otitis media (HP:0000389)1.93419660
130Anorexia (HP:0002039)1.93401139
131Abnormality of polysaccharide metabolism (HP:0011012)1.92332337
132Abnormality of glycosaminoglycan metabolism (HP:0004371)1.92332337
133Abnormality of mucopolysaccharide metabolism (HP:0011020)1.92332337
134Pulmonary embolism (HP:0002204)1.89463934
135Gangrene (HP:0100758)1.87811661
136Frequent falls (HP:0002359)1.85696274
137Hyperlipoproteinemia (HP:0010980)1.85444581
138Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.84133529
139Peripheral demyelination (HP:0011096)1.83738831
140Epidermoid cyst (HP:0200040)1.83415099
141Abnormality of transition element cation homeostasis (HP:0011030)1.83042525
142Distal arthrogryposis (HP:0005684)1.81224558
143Abnormality of fatty-acid metabolism (HP:0004359)1.78969463
144Hypercholesterolemia (HP:0003124)1.77670976
145Esophageal varix (HP:0002040)1.77642999
146Sepsis (HP:0100806)1.76648218

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.34789243
2BLK4.09507316
3MAP3K143.44291441
4IRAK43.24974062
5PBK3.23440345
6TBK12.99058113
7EPHB12.82029884
8TYK22.60349316
9ERN12.51537241
10MAP4K12.27192515
11TTN2.14430760
12MAP3K132.11685708
13IKBKE2.05937110
14TAOK21.95921090
15TAOK31.94745709
16IKBKB1.80826214
17KSR21.77096468
18IRAK31.74042233
19JAK11.65674105
20NME21.61221336
21PRPF4B1.60676721
22TXK1.59957306
23KIT1.50117471
24BMX1.49705760
25OBSCN1.44476714
26CSK1.39339932
27MAP2K31.35410630
28JAK31.35099483
29TAOK11.33527860
30TRPM71.32656634
31ARAF1.31730913
32PIK3CG1.28353011
33LIMK11.23518427
34STK101.22478603
35BMPR21.21355927
36MARK31.19676646
37ABL21.16908388
38FGR1.16712039
39JAK21.14974491
40ADRBK21.14462507
41HCK1.12516769
42ACVR1B1.11156578
43TNK21.10732952
44BTK1.06070970
45TGFBR21.03808695
46DDR21.03728584
47TESK11.03717024
48MST1R1.02391271
49SYK0.98895412
50PIM20.97018197
51MUSK0.96409908
52FGFR40.95573393
53FES0.95427608
54ZAP700.93488965
55ERBB40.92901280
56TESK20.91550004
57LYN0.90415803
58CSF1R0.88393533
59MATK0.88200472
60NEK90.86712369
61MAP2K60.86459648
62IRAK20.80523866
63SIK10.78950423
64SIK30.78630796
65EPHA30.78426797
66MAP3K90.77797934
67LCK0.77191575
68CDC42BPA0.76967284
69MOS0.76342682
70STK40.75031554
71MAP3K50.70145063
72MAP3K110.69965427
73CHUK0.69922058
74PIM10.69494969
75TEC0.69264770
76MAP3K30.68001011
77MAP3K10.67350956
78PRKCD0.64611453
79PDPK10.64197801
80PKN10.59905785
81MST40.57904290
82ABL10.56787959
83PTK60.55079717
84PTK2B0.54865132
85PRKCQ0.53907765
86MAP3K20.49690618
87RAF10.49672090
88DAPK20.48233485
89LRRK20.47457454
90PHKG20.46314913
91PHKG10.46314913
92PDK10.44814995
93EGFR0.44588522
94GRK70.44444898
95RIPK10.43977378
96PRKAA20.43557594
97MAPK40.42752413
98ITK0.41911368
99GRK60.41459462
100PRKG20.40476615
101FYN0.37705291
102YES10.37006452
103CAMKK20.36131823
104CLK10.36122848
105MET0.35978752
106HIPK20.35970623
107MAP3K120.33183423
108RPS6KA60.32378697
109PAK10.32238163
110MAP3K70.31991960
111PINK10.31530196
112MAPK120.31459271
113CDK60.31342728
114MAPKAPK20.29865405
115BCKDK0.29305938
116RPS6KL10.27816909
117RPS6KC10.27816909
118GSK3A0.26838333
119IRAK10.25885255
120MAP3K60.25501641
121MAP2K10.24389167
122GRK50.23561813
123KDR0.22974384
124EIF2AK10.22152320
125PDGFRB0.17837664

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.74126417
2Staphylococcus aureus infection_Homo sapiens_hsa051503.70895361
3Leishmaniasis_Homo sapiens_hsa051403.09010662
4Legionellosis_Homo sapiens_hsa051342.40155326
5Pertussis_Homo sapiens_hsa051332.18696782
6Autoimmune thyroid disease_Homo sapiens_hsa053202.14329468
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.07892349
8Graft-versus-host disease_Homo sapiens_hsa053322.02351500
9Arginine biosynthesis_Homo sapiens_hsa002201.94069017
10Complement and coagulation cascades_Homo sapiens_hsa046101.89364818
11NOD-like receptor signaling pathway_Homo sapiens_hsa046211.89301132
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.88230312
13Caffeine metabolism_Homo sapiens_hsa002321.85885993
14Osteoclast differentiation_Homo sapiens_hsa043801.84596200
15Tuberculosis_Homo sapiens_hsa051521.77022602
16Malaria_Homo sapiens_hsa051441.74292791
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.69667991
18Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.68318452
19Platelet activation_Homo sapiens_hsa046111.66690632
20NF-kappa B signaling pathway_Homo sapiens_hsa040641.65353100
21Rheumatoid arthritis_Homo sapiens_hsa053231.60282425
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.59020429
23Phagosome_Homo sapiens_hsa041451.56809294
24Primary immunodeficiency_Homo sapiens_hsa053401.56690415
25Histidine metabolism_Homo sapiens_hsa003401.54605090
26TNF signaling pathway_Homo sapiens_hsa046681.51494567
27Antigen processing and presentation_Homo sapiens_hsa046121.50977169
28Asthma_Homo sapiens_hsa053101.49399826
29Salmonella infection_Homo sapiens_hsa051321.45894160
30Lysosome_Homo sapiens_hsa041421.44694361
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.43274367
32RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.38326945
33Starch and sucrose metabolism_Homo sapiens_hsa005001.38139503
34Pentose and glucuronate interconversions_Homo sapiens_hsa000401.38126763
35Steroid biosynthesis_Homo sapiens_hsa001001.29207657
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.26946264
37T cell receptor signaling pathway_Homo sapiens_hsa046601.21657394
38Allograft rejection_Homo sapiens_hsa053301.20741037
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.14115607
40African trypanosomiasis_Homo sapiens_hsa051431.11797739
41Peroxisome_Homo sapiens_hsa041461.09153588
42Influenza A_Homo sapiens_hsa051641.08908727
43Toxoplasmosis_Homo sapiens_hsa051451.03658821
44Measles_Homo sapiens_hsa051621.01583740
45B cell receptor signaling pathway_Homo sapiens_hsa046620.99331466
46Fatty acid degradation_Homo sapiens_hsa000710.98439762
47Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.96440543
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.95537058
49Type I diabetes mellitus_Homo sapiens_hsa049400.93937884
50Intestinal immune network for IgA production_Homo sapiens_hsa046720.93311591
51Chemokine signaling pathway_Homo sapiens_hsa040620.92463717
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92201330
53Tryptophan metabolism_Homo sapiens_hsa003800.91758440
54Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.91563590
55Hematopoietic cell lineage_Homo sapiens_hsa046400.91450941
56Fatty acid elongation_Homo sapiens_hsa000620.91029493
57Glycosaminoglycan degradation_Homo sapiens_hsa005310.88366943
58Other glycan degradation_Homo sapiens_hsa005110.87188932
59Shigellosis_Homo sapiens_hsa051310.86466865
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85295464
61Apoptosis_Homo sapiens_hsa042100.82587403
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.82446567
63Leukocyte transendothelial migration_Homo sapiens_hsa046700.81973503
64Amoebiasis_Homo sapiens_hsa051460.81584876
65ABC transporters_Homo sapiens_hsa020100.81024980
66PPAR signaling pathway_Homo sapiens_hsa033200.80767835
67Adipocytokine signaling pathway_Homo sapiens_hsa049200.80497626
68Sulfur metabolism_Homo sapiens_hsa009200.78488706
69Vitamin digestion and absorption_Homo sapiens_hsa049770.74444621
70Folate biosynthesis_Homo sapiens_hsa007900.73016975
71beta-Alanine metabolism_Homo sapiens_hsa004100.71703828
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70164801
73Collecting duct acid secretion_Homo sapiens_hsa049660.69668344
74Fat digestion and absorption_Homo sapiens_hsa049750.69208815
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68952928
76Hepatitis C_Homo sapiens_hsa051600.68138836
77Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67988977
78Chemical carcinogenesis_Homo sapiens_hsa052040.67544837
79Bladder cancer_Homo sapiens_hsa052190.66197994
80Epstein-Barr virus infection_Homo sapiens_hsa051690.66083921
81VEGF signaling pathway_Homo sapiens_hsa043700.64686140
82Prolactin signaling pathway_Homo sapiens_hsa049170.62857081
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62250093
84Fatty acid metabolism_Homo sapiens_hsa012120.61943028
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61478147
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60878162
87Insulin resistance_Homo sapiens_hsa049310.60317644
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60187741
89Renin-angiotensin system_Homo sapiens_hsa046140.58915234
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58892967
91Pancreatic cancer_Homo sapiens_hsa052120.57670754
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56075501
93Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55974892
94Phenylalanine metabolism_Homo sapiens_hsa003600.55863350
95Herpes simplex infection_Homo sapiens_hsa051680.55518520
96Type II diabetes mellitus_Homo sapiens_hsa049300.55258818
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.55250608
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.54705216
99Pentose phosphate pathway_Homo sapiens_hsa000300.54113542
100Prion diseases_Homo sapiens_hsa050200.53610482
101Mineral absorption_Homo sapiens_hsa049780.52344575
102Galactose metabolism_Homo sapiens_hsa000520.52200570
103Systemic lupus erythematosus_Homo sapiens_hsa053220.52123018
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.48935288
105Steroid hormone biosynthesis_Homo sapiens_hsa001400.48481213
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.48174939
107Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47942309
108Viral carcinogenesis_Homo sapiens_hsa052030.47827693
109Viral myocarditis_Homo sapiens_hsa054160.46219563
110Endocytosis_Homo sapiens_hsa041440.43774795
111Chronic myeloid leukemia_Homo sapiens_hsa052200.43419050
112Drug metabolism - other enzymes_Homo sapiens_hsa009830.42377417
113Hepatitis B_Homo sapiens_hsa051610.41327417
114Retinol metabolism_Homo sapiens_hsa008300.41008795
115Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40908587
116Non-small cell lung cancer_Homo sapiens_hsa052230.40722942
117Neurotrophin signaling pathway_Homo sapiens_hsa047220.39314681
118Bile secretion_Homo sapiens_hsa049760.38917994
119Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37436114
120Carbon metabolism_Homo sapiens_hsa012000.37101656
121Arachidonic acid metabolism_Homo sapiens_hsa005900.36958998
122AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36392456
123Acute myeloid leukemia_Homo sapiens_hsa052210.35628639
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35175354
125HTLV-I infection_Homo sapiens_hsa051660.31944673
126HIF-1 signaling pathway_Homo sapiens_hsa040660.30957090
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30835478
128Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.28752552
129Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28654916
130Sphingolipid metabolism_Homo sapiens_hsa006000.28400318
131Renal cell carcinoma_Homo sapiens_hsa052110.26768258
132FoxO signaling pathway_Homo sapiens_hsa040680.24225987
133Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.23202223
134Phospholipase D signaling pathway_Homo sapiens_hsa040720.22873732
135Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.21155272
136Dorso-ventral axis formation_Homo sapiens_hsa043200.15257352
137MAPK signaling pathway_Homo sapiens_hsa040100.14574172
138Regulation of actin cytoskeleton_Homo sapiens_hsa048100.11396722
139Small cell lung cancer_Homo sapiens_hsa052220.10804267
140GnRH signaling pathway_Homo sapiens_hsa049120.10309278

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