PTCD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleobase biosynthetic process (GO:0046112)5.07062470
2purine nucleobase biosynthetic process (GO:0009113)4.91570399
3nuclear pore organization (GO:0006999)4.88070234
4IMP biosynthetic process (GO:0006188)4.77756830
5nuclear pore complex assembly (GO:0051292)4.73117997
6DNA replication initiation (GO:0006270)4.56983592
7DNA unwinding involved in DNA replication (GO:0006268)4.48041740
8protein localization to kinetochore (GO:0034501)4.38423007
9mitotic metaphase plate congression (GO:0007080)4.35464034
10folic acid-containing compound biosynthetic process (GO:0009396)4.24685833
11sister chromatid segregation (GO:0000819)4.24528403
12mitotic sister chromatid segregation (GO:0000070)4.22782046
13DNA strand elongation involved in DNA replication (GO:0006271)4.22127843
14IMP metabolic process (GO:0046040)4.22101614
15chromatin remodeling at centromere (GO:0031055)4.15493568
16CENP-A containing nucleosome assembly (GO:0034080)4.14239751
17formation of translation preinitiation complex (GO:0001731)4.04801832
18DNA double-strand break processing (GO:0000729)4.04687600
19DNA strand elongation (GO:0022616)3.99682377
20mitotic nuclear envelope disassembly (GO:0007077)3.98345076
21metaphase plate congression (GO:0051310)3.97075179
22resolution of meiotic recombination intermediates (GO:0000712)3.95132266
23regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.93984433
24telomere maintenance via semi-conservative replication (GO:0032201)3.93584908
25DNA replication checkpoint (GO:0000076)3.93578633
26mitotic chromosome condensation (GO:0007076)3.92243200
27ribosomal small subunit assembly (GO:0000028)3.90469654
28kinetochore organization (GO:0051383)3.82030796
29DNA replication-dependent nucleosome assembly (GO:0006335)3.73575024
30DNA replication-dependent nucleosome organization (GO:0034723)3.73575024
31protein localization to chromosome, centromeric region (GO:0071459)3.70946781
32DNA replication-independent nucleosome assembly (GO:0006336)3.70015630
33DNA replication-independent nucleosome organization (GO:0034724)3.70015630
34non-recombinational repair (GO:0000726)3.68414891
35double-strand break repair via nonhomologous end joining (GO:0006303)3.68414891
36membrane disassembly (GO:0030397)3.68406216
37nuclear envelope disassembly (GO:0051081)3.68406216
38somatic diversification of immune receptors via somatic mutation (GO:0002566)3.66352625
39somatic hypermutation of immunoglobulin genes (GO:0016446)3.66352625
40histone-serine phosphorylation (GO:0035404)3.64075103
41telomere maintenance via recombination (GO:0000722)3.62294870
42mitotic recombination (GO:0006312)3.58362520
43histone exchange (GO:0043486)3.55692434
44pore complex assembly (GO:0046931)3.51354105
45regulation of spindle organization (GO:0090224)3.47677840
46establishment of chromosome localization (GO:0051303)3.46244480
47spindle checkpoint (GO:0031577)3.45491702
48replication fork processing (GO:0031297)3.44177926
49telomere maintenance via telomere lengthening (GO:0010833)3.43972902
50ribosome biogenesis (GO:0042254)3.41057376
51regulation of centrosome cycle (GO:0046605)3.40091580
52centriole replication (GO:0007099)3.38650237
53regulation of centriole replication (GO:0046599)3.34682232
54regulation of helicase activity (GO:0051095)3.34186797
55DNA ligation (GO:0006266)3.34050358
56mitotic spindle checkpoint (GO:0071174)3.33516364
57postreplication repair (GO:0006301)3.33309997
58DNA duplex unwinding (GO:0032508)3.32474271
59meiotic chromosome segregation (GO:0045132)3.32287492
60viral mRNA export from host cell nucleus (GO:0046784)3.32107735
61regulation of mitotic spindle checkpoint (GO:1903504)3.31750505
62regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.31750505
63DNA geometric change (GO:0032392)3.30201362
64ribosome assembly (GO:0042255)3.28703899
65nucleotide-excision repair, DNA gap filling (GO:0006297)3.27700788
66regulation of nuclear cell cycle DNA replication (GO:0033262)3.27282789
67attachment of spindle microtubules to kinetochore (GO:0008608)3.22486922
68negative regulation of DNA-dependent DNA replication (GO:2000104)3.21850495
69UDP-N-acetylglucosamine metabolic process (GO:0006047)3.20321649
70regulation of chromosome segregation (GO:0051983)3.17409270
71negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.16457631
72negative regulation of sister chromatid segregation (GO:0033046)3.16457631
73negative regulation of mitotic sister chromatid separation (GO:2000816)3.16457631
74negative regulation of mitotic sister chromatid segregation (GO:0033048)3.16457631
75kinetochore assembly (GO:0051382)3.16346587
76synapsis (GO:0007129)3.15885614
77negative regulation of chromosome segregation (GO:0051985)3.15730198
78regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.15428548
79termination of RNA polymerase II transcription (GO:0006369)3.15372589
80histone H2A acetylation (GO:0043968)3.15052524
81mitochondrial RNA metabolic process (GO:0000959)3.14318642
82spindle assembly checkpoint (GO:0071173)3.11993184
83mismatch repair (GO:0006298)3.11128102
84negative regulation of DNA recombination (GO:0045910)3.10427534
85regulation of mitotic metaphase/anaphase transition (GO:0030071)3.08702188
86mitotic spindle assembly checkpoint (GO:0007094)3.06278830
87negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.05284939
88negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.04138533
89RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.04043476
90regulation of mitotic spindle organization (GO:0060236)3.03691098
91cullin deneddylation (GO:0010388)3.03555914
92folic acid metabolic process (GO:0046655)3.01721154
93regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.00245004
94rRNA modification (GO:0000154)3.00033898
95regulation of DNA endoreduplication (GO:0032875)2.99949339
96transcription from mitochondrial promoter (GO:0006390)2.99559006
97maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.99387754
98regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.98671319
99one-carbon metabolic process (GO:0006730)2.98430134
100reciprocal meiotic recombination (GO:0007131)2.96488378
101reciprocal DNA recombination (GO:0035825)2.96488378
102chromosome segregation (GO:0007059)2.95080537
103regulation of sister chromatid segregation (GO:0033045)2.94628958
104regulation of mitotic sister chromatid separation (GO:0010965)2.94628958
105regulation of mitotic sister chromatid segregation (GO:0033047)2.94628958
106mitotic G2/M transition checkpoint (GO:0044818)2.94091354
107translesion synthesis (GO:0019985)2.93964204
108protein K6-linked ubiquitination (GO:0085020)2.93929816
109recombinational repair (GO:0000725)2.93268386
110regulation of centrosome duplication (GO:0010824)2.93217815
111mitotic sister chromatid cohesion (GO:0007064)2.93179616
112spliceosomal complex assembly (GO:0000245)2.92973646
113double-strand break repair via homologous recombination (GO:0000724)2.92371362
114ATP-dependent chromatin remodeling (GO:0043044)2.91937089
115tetrahydrofolate metabolic process (GO:0046653)2.90576148
116maturation of SSU-rRNA (GO:0030490)2.90412241
117DNA conformation change (GO:0071103)2.89786005
118chromatin assembly or disassembly (GO:0006333)2.89776089
119telomere maintenance (GO:0000723)2.89307758
120negative regulation of activin receptor signaling pathway (GO:0032926)2.89096875
121telomere organization (GO:0032200)2.86967819
122DNA catabolic process, exonucleolytic (GO:0000738)2.84591264
123positive regulation of chromosome segregation (GO:0051984)2.84104160
124negative regulation of cell cycle G2/M phase transition (GO:1902750)2.83804235
125protein deneddylation (GO:0000338)2.80810294
126regulation of spindle checkpoint (GO:0090231)2.73777540
127establishment of integrated proviral latency (GO:0075713)2.73417695
128somatic recombination of immunoglobulin gene segments (GO:0016447)2.72317128
129somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.72294723
130somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.72294723
131isotype switching (GO:0045190)2.72294723
132prenylation (GO:0097354)2.71119637
133protein prenylation (GO:0018342)2.71119637
134regulation of sister chromatid cohesion (GO:0007063)2.69886846

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.76647980
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.49443636
3RBPJ_22232070_ChIP-Seq_NCS_Mouse4.44100191
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.36969492
5FOXM1_23109430_ChIP-Seq_U2OS_Human4.07818970
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.28975655
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.07649334
8* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.07117350
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.02094884
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.89528097
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.88639075
12* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.85605679
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.68554060
14ZNF274_21170338_ChIP-Seq_K562_Hela2.58794744
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.55942507
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.54595236
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.52675940
18ESR1_15608294_ChIP-ChIP_MCF-7_Human2.50011407
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.48370402
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.46230412
21* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.40165251
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.35843993
23GABP_17652178_ChIP-ChIP_JURKAT_Human2.33032639
24AR_21909140_ChIP-Seq_LNCAP_Human2.30514813
25* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.28974133
26E2F1_21310950_ChIP-Seq_MCF-7_Human2.28048497
27NANOG_18555785_ChIP-Seq_MESCs_Mouse2.13511340
28* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.13239742
29FUS_26573619_Chip-Seq_HEK293_Human2.11411205
30* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05183301
31* VDR_23849224_ChIP-Seq_CD4+_Human2.04196302
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03117140
33* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98956677
34* XRN2_22483619_ChIP-Seq_HELA_Human1.91526589
35VDR_22108803_ChIP-Seq_LS180_Human1.90918919
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.87992231
37* FOXP3_21729870_ChIP-Seq_TREG_Human1.86382314
38* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.86226976
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84320475
40ELK1_19687146_ChIP-ChIP_HELA_Human1.83817810
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81882056
42FLI1_27457419_Chip-Seq_LIVER_Mouse1.78232746
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.77935193
44SALL1_21062744_ChIP-ChIP_HESCs_Human1.73633213
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.72071950
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.71229065
47HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.69772720
48POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.65958578
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64284863
50SOX2_18555785_ChIP-Seq_MESCs_Mouse1.62212169
51* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.61100103
52MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.60461347
53POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.58344324
54CIITA_25753668_ChIP-Seq_RAJI_Human1.57857366
55DCP1A_22483619_ChIP-Seq_HELA_Human1.54292786
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.51886719
57GABP_19822575_ChIP-Seq_HepG2_Human1.51745401
58* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46932917
59TAF15_26573619_Chip-Seq_HEK293_Human1.46766027
60* TTF2_22483619_ChIP-Seq_HELA_Human1.46677369
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.46347577
62HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44295820
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.43459435
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.42943164
65* SRF_21415370_ChIP-Seq_HL-1_Mouse1.41216524
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41085911
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38438792
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.35720316
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34912539
70ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33394089
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29323157
72P300_19829295_ChIP-Seq_ESCs_Human1.28753766
73KDM5A_27292631_Chip-Seq_BREAST_Human1.28662115
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23060511
75NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.21364796
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.20806031
77GATA1_22025678_ChIP-Seq_K562_Human1.18057531
78HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16548545
79RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15891187
80GBX2_23144817_ChIP-Seq_PC3_Human1.15400372
81MYC_18940864_ChIP-ChIP_HL60_Human1.09226186
82EGR1_19374776_ChIP-ChIP_THP-1_Human1.08577937
83SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.08059160
84CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07414911
85PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07248270
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06560099
87TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.06040687
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.05664823
89SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.05443595
90NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.05033025
91EWS_26573619_Chip-Seq_HEK293_Human1.02184353
92E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01326733
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00526821
94SUZ12_27294783_Chip-Seq_NPCs_Mouse0.98989671
95SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.97999824
96NANOG_16153702_ChIP-ChIP_HESCs_Human0.97629503
97CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97153530
98MYC_22102868_ChIP-Seq_BL_Human0.96930011
99ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96252179
100IRF1_19129219_ChIP-ChIP_H3396_Human0.96040025
101KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95795062
102SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95416258
103EZH2_27294783_Chip-Seq_NPCs_Mouse0.94966036
104* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94938043
105ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.94880982
106IGF1R_20145208_ChIP-Seq_DFB_Human0.94200979
107RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.93586580
108TCF3_18692474_ChIP-Seq_MESCs_Mouse0.93298750
109CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92813240
110KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90530412
111CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90524837
112FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.90342500
113NFE2_27457419_Chip-Seq_LIVER_Mouse0.90315770
114PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.89393328
115KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.89159081
116KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.89159081
117KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.89159081
118NANOG_21062744_ChIP-ChIP_HESCs_Human0.88766394
119TP53_22573176_ChIP-Seq_HFKS_Human0.88330675
120CBP_20019798_ChIP-Seq_JUKART_Human0.88150857
121IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.88150857
122ER_23166858_ChIP-Seq_MCF-7_Human0.87608747
123GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87407025
124SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.87057360
125PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86945988
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86888504
127SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.86667623
128SOX2_16153702_ChIP-ChIP_HESCs_Human0.86238195
129STAT3_23295773_ChIP-Seq_U87_Human0.85175362
130TFEB_21752829_ChIP-Seq_HELA_Human0.85064462
131SOX9_26525672_Chip-Seq_HEART_Mouse0.84902257
132CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84505399
133BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84244150
134AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84004748
135MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.83546336
136CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83352641
137CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83029035
138NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.80526297
139NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.79431587

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.10079392
2MP0010094_abnormal_chromosome_stability4.79060225
3MP0003111_abnormal_nucleus_morphology3.96099428
4MP0008057_abnormal_DNA_replication3.76045615
5MP0004957_abnormal_blastocyst_morpholog3.73710178
6MP0003123_paternal_imprinting3.66189282
7MP0003077_abnormal_cell_cycle3.44956569
8MP0008058_abnormal_DNA_repair3.15510168
9MP0003806_abnormal_nucleotide_metabolis2.92371814
10MP0008877_abnormal_DNA_methylation2.71883555
11MP0008007_abnormal_cellular_replicative2.54587179
12MP0001730_embryonic_growth_arrest2.28045902
13MP0008932_abnormal_embryonic_tissue2.19561124
14MP0003121_genomic_imprinting2.05721194
15MP0002396_abnormal_hematopoietic_system1.91071647
16MP0000350_abnormal_cell_proliferation1.86938276
17MP0004084_abnormal_cardiac_muscle1.86742580
18MP0009697_abnormal_copulation1.86448432
19MP0004147_increased_porphyrin_level1.80686322
20MP0001672_abnormal_embryogenesis/_devel1.79372046
21MP0005380_embryogenesis_phenotype1.79372046
22MP0003984_embryonic_growth_retardation1.70754212
23MP0001529_abnormal_vocalization1.69184784
24MP0009672_abnormal_birth_weight1.68373517
25MP0002088_abnormal_embryonic_growth/wei1.65808998
26MP0003786_premature_aging1.62965413
27MP0004215_abnormal_myocardial_fiber1.60682174
28MP0001697_abnormal_embryo_size1.59328969
29MP0002102_abnormal_ear_morphology1.58318434
30MP0000566_synostosis1.57553354
31MP0002837_dystrophic_cardiac_calcinosis1.52871473
32MP0003567_abnormal_fetal_cardiomyocyte1.51687379
33MP0004197_abnormal_fetal_growth/weight/1.51407700
34MP0002938_white_spotting1.48282539
35MP0010352_gastrointestinal_tract_polyps1.46499280
36MP0006035_abnormal_mitochondrial_morpho1.46471856
37MP0002086_abnormal_extraembryonic_tissu1.43372143
38MP0008995_early_reproductive_senescence1.42325614
39MP0002080_prenatal_lethality1.41633034
40MP0004145_abnormal_muscle_electrophysio1.41468140
41MP0003718_maternal_effect1.39249179
42MP0000372_irregular_coat_pigmentation1.39067815
43MP0003136_yellow_coat_color1.39064249
44MP0006036_abnormal_mitochondrial_physio1.38137303
45MP0005330_cardiomyopathy1.37909390
46MP0010307_abnormal_tumor_latency1.36716870
47MP0002085_abnormal_embryonic_tissue1.34450447
48MP0003941_abnormal_skin_development1.28030214
49MP0000749_muscle_degeneration1.27117011
50MP0004808_abnormal_hematopoietic_stem1.25712402
51MP0002269_muscular_atrophy1.24835065
52MP0006072_abnormal_retinal_apoptosis1.24399321
53MP0002084_abnormal_developmental_patter1.24052648
54MP0002736_abnormal_nociception_after1.22865866
55MP0001293_anophthalmia1.21488494
56MP0006292_abnormal_olfactory_placode1.20240451
57MP0001984_abnormal_olfaction1.13480895
58MP0000313_abnormal_cell_death1.12661911
59MP0009703_decreased_birth_body1.11219940
60MP0000537_abnormal_urethra_morphology1.09232440
61MP0000427_abnormal_hair_cycle1.07511949
62MP0002009_preneoplasia1.07279711
63MP0002210_abnormal_sex_determination1.06100972
64MP0008789_abnormal_olfactory_epithelium1.04029754
65MP0005551_abnormal_eye_electrophysiolog1.03148102
66MP0003890_abnormal_embryonic-extraembry1.02041348
67MP0000569_abnormal_digit_pigmentation1.01300894
68MP0004087_abnormal_muscle_fiber1.01151323
69MP0000647_abnormal_sebaceous_gland1.00565624
70MP0003137_abnormal_impulse_conducting1.00477528
71MP0003315_abnormal_perineum_morphology1.00400459
72MP0005253_abnormal_eye_physiology1.00211700
73MP0005171_absent_coat_pigmentation0.99078335
74MP0005187_abnormal_penis_morphology0.97658496
75MP0006138_congestive_heart_failure0.95486740
76MP0009053_abnormal_anal_canal0.94669949
77MP0002160_abnormal_reproductive_system0.93828474
78MP0003646_muscle_fatigue0.92807501
79MP0002233_abnormal_nose_morphology0.92217444
80MP0002751_abnormal_autonomic_nervous0.92043730
81MP0000490_abnormal_crypts_of0.91769123
82MP0006276_abnormal_autonomic_nervous0.91755289
83MP0010630_abnormal_cardiac_muscle0.90745864
84MP0005266_abnormal_metabolism0.90583199
85MP0001119_abnormal_female_reproductive0.90175976
86MP0003698_abnormal_male_reproductive0.90015466
87MP0000631_abnormal_neuroendocrine_gland0.88955743
88MP0003195_calcinosis0.88517761
89MP0001346_abnormal_lacrimal_gland0.87865599
90MP0002019_abnormal_tumor_incidence0.86804817
91MP0003221_abnormal_cardiomyocyte_apopto0.86456368
92MP0002075_abnormal_coat/hair_pigmentati0.86411660
93MP0000750_abnormal_muscle_regeneration0.85852107
94MP0002163_abnormal_gland_morphology0.85582137
95MP0001544_abnormal_cardiovascular_syste0.85514434
96MP0005385_cardiovascular_system_phenoty0.85514434
97MP0002127_abnormal_cardiovascular_syste0.84463876
98MP0001145_abnormal_male_reproductive0.82973981
99MP0002876_abnormal_thyroid_physiology0.82828518
100MP0005499_abnormal_olfactory_system0.81971288
101MP0005394_taste/olfaction_phenotype0.81971288
102MP0002638_abnormal_pupillary_reflex0.81926034
103MP0003705_abnormal_hypodermis_morpholog0.80186074
104MP0001661_extended_life_span0.80134478
105MP0005367_renal/urinary_system_phenotyp0.79335345
106MP0000516_abnormal_urinary_system0.79335345
107MP0004036_abnormal_muscle_relaxation0.77636194
108MP0003937_abnormal_limbs/digits/tail_de0.77478955
109MP0004133_heterotaxia0.77291071
110MP0001929_abnormal_gametogenesis0.77167272
111MP0003828_pulmonary_edema0.76966944
112MP0008260_abnormal_autophagy0.76168706
113MP0003119_abnormal_digestive_system0.76103968
114MP0003787_abnormal_imprinting0.75451684
115MP0001186_pigmentation_phenotype0.74142928
116MP0005085_abnormal_gallbladder_physiolo0.73680302
117MP0003861_abnormal_nervous_system0.73311061
118MP0005389_reproductive_system_phenotype0.72750323
119MP0002697_abnormal_eye_size0.72695605
120MP0003880_abnormal_central_pattern0.72590464
121MP0002234_abnormal_pharynx_morphology0.72412734
122MP0003755_abnormal_palate_morphology0.71930105
123MP0000653_abnormal_sex_gland0.71867957
124MP0000266_abnormal_heart_morphology0.71752087
125MP0001485_abnormal_pinna_reflex0.71730226
126MP0002139_abnormal_hepatobiliary_system0.71421091
127MP0001764_abnormal_homeostasis0.71188612
128MP0001968_abnormal_touch/_nociception0.71178379
129MP0002111_abnormal_tail_morphology0.70496743
130MP0000015_abnormal_ear_pigmentation0.70141673
131MP0001177_atelectasis0.69835161
132MP0000759_abnormal_skeletal_muscle0.68786300
133MP0000049_abnormal_middle_ear0.68503500
134MP0000358_abnormal_cell_content/0.66060917
135MP0001915_intracranial_hemorrhage0.65816418
136MP0010030_abnormal_orbit_morphology0.64709055
137MP0002972_abnormal_cardiac_muscle0.64622190
138MP0008775_abnormal_heart_ventricle0.64257028
139MP0004185_abnormal_adipocyte_glucose0.64199953
140MP0001286_abnormal_eye_development0.63215665
141MP0002095_abnormal_skin_pigmentation0.62942664
142MP0004484_altered_response_of0.61154134

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.88104897
2Reduced antithrombin III activity (HP:0001976)4.53046182
3Abnormality of pyruvate family amino acid metabolism (HP:0010915)4.24785474
4Abnormality of alanine metabolism (HP:0010916)4.24785474
5Hyperalaninemia (HP:0003348)4.24785474
6Chromsome breakage (HP:0040012)4.09159353
7Gonadotropin excess (HP:0000837)3.69867146
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.66565551
9Type I transferrin isoform profile (HP:0003642)3.52339216
10Ependymoma (HP:0002888)3.22763814
11Breast hypoplasia (HP:0003187)3.19307219
12Abnormality of chromosome stability (HP:0003220)3.01218459
13Volvulus (HP:0002580)2.99289862
14Abnormality of the labia minora (HP:0012880)2.98870389
15Oral leukoplakia (HP:0002745)2.94333782
16Medulloblastoma (HP:0002885)2.88797012
17Hyperglycinemia (HP:0002154)2.79164817
18Agnosia (HP:0010524)2.78322518
19Patellar aplasia (HP:0006443)2.76860670
20Meckel diverticulum (HP:0002245)2.72982468
21Hypoproteinemia (HP:0003075)2.72295062
22Abnormality of the preputium (HP:0100587)2.63661154
23Abnormality of serum amino acid levels (HP:0003112)2.63165915
24Impulsivity (HP:0100710)2.60442264
25Colon cancer (HP:0003003)2.56632407
26Abnormality of the ileum (HP:0001549)2.56049518
27Abnormality of glycolysis (HP:0004366)2.52134011
28Increased serum pyruvate (HP:0003542)2.52134011
29Aplasia/Hypoplasia of the patella (HP:0006498)2.52039160
30Rhabdomyosarcoma (HP:0002859)2.49940797
31Aplasia/Hypoplasia of the uvula (HP:0010293)2.49511691
32Selective tooth agenesis (HP:0001592)2.48349738
33Abnormal lung lobation (HP:0002101)2.46314131
34Hypoplasia of the pons (HP:0012110)2.41951316
35Pancreatic islet-cell hyperplasia (HP:0004510)2.41447186
36Abnormality of pyrimidine metabolism (HP:0004353)2.39206019
37Pancreatic cysts (HP:0001737)2.38909500
38Absent radius (HP:0003974)2.38374413
39Aplasia/Hypoplasia of the sternum (HP:0006714)2.38090087
40Hyperglycinuria (HP:0003108)2.36565776
41Biliary tract neoplasm (HP:0100574)2.34971388
42Intestinal atresia (HP:0011100)2.31930200
43Abnormality of the pons (HP:0007361)2.31346816
44Cerebellar dysplasia (HP:0007033)2.26956679
45Basal cell carcinoma (HP:0002671)2.25498521
46Small intestinal stenosis (HP:0012848)2.24908497
47Duodenal stenosis (HP:0100867)2.24908497
48Abnormality of the astrocytes (HP:0100707)2.23844026
49Astrocytoma (HP:0009592)2.23844026
50Abnormality of methionine metabolism (HP:0010901)2.20195739
51Neoplasm of the colon (HP:0100273)2.20000028
52Neoplasm of the rectum (HP:0100743)2.18609746
53Absent forearm bone (HP:0003953)2.18467758
54Aplasia involving forearm bones (HP:0009822)2.18467758
55Sloping forehead (HP:0000340)2.17169237
56Capillary hemangiomas (HP:0005306)2.16409081
57Molar tooth sign on MRI (HP:0002419)2.14400257
58Abnormality of midbrain morphology (HP:0002418)2.14400257
59Amyotrophic lateral sclerosis (HP:0007354)2.13680234
60Myelodysplasia (HP:0002863)2.12796217
61Pancreatic fibrosis (HP:0100732)2.12183194
62Abnormality of the anterior horn cell (HP:0006802)2.12178292
63Degeneration of anterior horn cells (HP:0002398)2.12178292
64Microvesicular hepatic steatosis (HP:0001414)2.12021977
65Exercise-induced muscle cramps (HP:0003710)2.10490856
66Renal cortical cysts (HP:0000803)2.10189057
67Gaze-evoked nystagmus (HP:0000640)2.08536942
68Breast aplasia (HP:0100783)2.08348906
69Cleft eyelid (HP:0000625)2.07802348
70Facial cleft (HP:0002006)2.06125761
71Nephroblastoma (Wilms tumor) (HP:0002667)2.05824826
72Methylmalonic acidemia (HP:0002912)2.04656827
73Abnormality of homocysteine metabolism (HP:0010919)2.02338733
74Homocystinuria (HP:0002156)2.02338733
75Abnormality of the columella (HP:0009929)2.00662341
76Abnormal biliary tract morphology (HP:0012440)2.00630670
77Bone marrow hypocellularity (HP:0005528)2.00304110
78Acute encephalopathy (HP:0006846)1.99156064
79Abnormality of the carotid arteries (HP:0005344)1.99010256
80Triphalangeal thumb (HP:0001199)1.98335327
81Glioma (HP:0009733)1.97611847
82Rhabdomyolysis (HP:0003201)1.97403603
83Supernumerary bones of the axial skeleton (HP:0009144)1.95348548
84Premature graying of hair (HP:0002216)1.95014446
85Absent thumb (HP:0009777)1.93115514
86Abnormal number of incisors (HP:0011064)1.92895057
87Abnormality of the lower motor neuron (HP:0002366)1.92385475
88Aplasia/Hypoplasia of the breasts (HP:0010311)1.91883429
89Embryonal renal neoplasm (HP:0011794)1.91755552
90Abnormality of the duodenum (HP:0002246)1.91367031
91True hermaphroditism (HP:0010459)1.91345804
92Abnormality of DNA repair (HP:0003254)1.90962580
93Neoplasm of the pancreas (HP:0002894)1.90098087
94Medial flaring of the eyebrow (HP:0010747)1.89791437
95Cellular immunodeficiency (HP:0005374)1.89537014
96Neoplasm of the small intestine (HP:0100833)1.88981451
97Abnormality of glycine metabolism (HP:0010895)1.86689879
98Abnormality of serine family amino acid metabolism (HP:0010894)1.86689879
99Increased nuchal translucency (HP:0010880)1.86456172
100Clubbing of toes (HP:0100760)1.85737431
101Abnormal protein glycosylation (HP:0012346)1.85653516
102Abnormal glycosylation (HP:0012345)1.85653516
103Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.85653516
104Abnormal protein N-linked glycosylation (HP:0012347)1.85653516
105Cafe-au-lait spot (HP:0000957)1.85558406
106Abnormality of the renal cortex (HP:0011035)1.85225466
107Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85210548
108Ovarian neoplasm (HP:0100615)1.83799978
109Supernumerary spleens (HP:0009799)1.83602133
110Supernumerary ribs (HP:0005815)1.82508827
111Acute necrotizing encephalopathy (HP:0006965)1.81422496
112Cerebral edema (HP:0002181)1.80989433
113Neuroblastoma (HP:0003006)1.80419729
114Primitive neuroectodermal tumor (HP:0030065)1.80419729
115Neuroblastic tumors (HP:0004376)1.80419729
116Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.80419729
117Nephronophthisis (HP:0000090)1.79798702
118Multiple enchondromatosis (HP:0005701)1.78608638
119Reticulocytopenia (HP:0001896)1.78182466
120Increased serum lactate (HP:0002151)1.77488554
121Hepatoblastoma (HP:0002884)1.76723417
122Atrophy/Degeneration involving motor neurons (HP:0007373)1.75718972
123Skull defect (HP:0001362)1.75428725
124Atrial fibrillation (HP:0005110)1.74521966
125Exotropia (HP:0000577)1.73794484
126Limb hypertonia (HP:0002509)1.73684816
127Neoplasm of the liver (HP:0002896)1.73612875
128Increased CSF lactate (HP:0002490)1.73408545
129Dandy-Walker malformation (HP:0001305)1.72267420
130Abolished electroretinogram (ERG) (HP:0000550)1.72265032
131Ectopic kidney (HP:0000086)1.71777232
132Long foot (HP:0001833)1.71052449
133Lipid accumulation in hepatocytes (HP:0006561)1.70645171
134Aplasia/Hypoplasia of the earlobes (HP:0009906)1.70438375
13511 pairs of ribs (HP:0000878)1.68299258
136Neoplasm of the oral cavity (HP:0100649)1.68153163
137Cortical dysplasia (HP:0002539)1.67989648
138Type II lissencephaly (HP:0007260)1.66844231
139Impaired proprioception (HP:0010831)1.66541571
140Abnormal mitochondria in muscle tissue (HP:0008316)1.62895098
141Poikiloderma (HP:0001029)1.62309209
142Congenital primary aphakia (HP:0007707)1.60412909
143Central scotoma (HP:0000603)1.60308320

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRSK24.32212068
2CDC74.20771133
3BRD43.67236697
4NEK13.46907660
5SRPK13.17630865
6WEE13.12853419
7BUB12.83920669
8PRPF4B2.81503622
9EPHA32.77741830
10LATS12.56223178
11BRSK12.54411028
12EIF2AK12.48125059
13TAOK22.46007858
14PBK2.43802718
15ZAK2.24490228
16TTK2.14755824
17FRK2.13974026
18TSSK62.06759396
19BCR2.01910620
20BMPR1B1.96505970
21CAMKK21.94670967
22PLK41.93297880
23NEK21.80035792
24PLK11.64967233
25TAF11.64045249
26AKT31.57576632
27MKNK11.53801998
28EIF2AK31.53720784
29TNIK1.49151458
30MAP3K41.46245233
31CCNB11.41912175
32PLK31.39925894
33PDK41.39514299
34PDK31.39514299
35MAP4K21.38066141
36AURKB1.35574039
37MST41.33182150
38ATR1.32948798
39MKNK21.24255670
40STK161.22362286
41CASK1.22168163
42CHEK21.21413214
43NUAK11.20258340
44PNCK1.18968701
45TLK11.18669909
46TRIM281.17146977
47PKN21.14075686
48NME11.13786983
49CHEK11.11948644
50OBSCN1.10552319
51CDK41.09660517
52RPS6KB21.09281231
53PASK1.04046685
54VRK11.02470279
55TRPM71.01461683
56VRK20.98809409
57STK38L0.95987850
58FLT30.95238036
59PLK20.95218625
60CDK70.94810240
61CDK120.92907932
62CSNK1G10.92499301
63EIF2AK20.89661795
64FGFR20.89294712
65STK40.84660226
66STK30.82246758
67MAPK130.81706506
68AURKA0.81147339
69TTN0.81130403
70ATM0.81100148
71STK390.79920116
72EPHA20.78252627
73PDGFRA0.77160038
74CSNK1G30.77022338
75CSNK1A1L0.76992801
76EPHA40.72157948
77MAP2K70.71354618
78MAP3K80.70779150
79CSNK1G20.70598830
80ACVR1B0.70416445
81PDK20.70078652
82NME20.68837742
83OXSR10.68310789
84PAK40.67937290
85MELK0.67300678
86BCKDK0.66095360
87CDK20.63212643
88CSNK2A20.61091881
89RPS6KA40.59340990
90CDK10.56656046
91WNK40.56438393
92GRK10.56228819
93CDK30.54641302
94PIK3CA0.54165110
95PAK30.53596649
96CDK60.53415143
97PHKG20.51955404
98PHKG10.51955404
99INSRR0.50891371
100PIM10.50590814
101ABL20.50355324
102ERBB40.49232612
103MAP3K100.47866694
104STK240.47080419
105SCYL20.44066104
106ALK0.43421425
107STK100.41950610
108NEK90.41307973
109RPS6KB10.39684435
110CSNK2A10.39567607
111CDK80.38069737
112TGFBR10.37743150
113RPS6KA50.37148396
114PRKCE0.36660578
115AKT20.36426938
116KSR10.36101061
117NEK60.35805677
118PRKDC0.33302607
119PRKACB0.33159398
120PINK10.32912946
121ERBB30.31986704
122BRAF0.31108409
123CAMKK10.31083338
124MARK30.30401152
125DAPK10.29316174
126PRKD20.28617999
127SGK20.25713048
128FGFR10.25048724
129DYRK30.24970320
130WNK30.24896752
131CSNK1D0.24493260
132AKT10.24403550
133YES10.23850082
134LATS20.22976139
135PRKAA10.22654829
136CLK10.20890749
137CSNK1E0.20513696

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.39583718
2DNA replication_Homo sapiens_hsa030304.38561000
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.85688032
4One carbon pool by folate_Homo sapiens_hsa006703.33789792
5Spliceosome_Homo sapiens_hsa030403.09549376
6RNA transport_Homo sapiens_hsa030132.92877632
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.88564400
8Homologous recombination_Homo sapiens_hsa034402.67568342
9Base excision repair_Homo sapiens_hsa034102.56917224
10Nucleotide excision repair_Homo sapiens_hsa034202.56021086
11Cell cycle_Homo sapiens_hsa041102.50014689
12RNA polymerase_Homo sapiens_hsa030202.47270162
13Proteasome_Homo sapiens_hsa030502.45185221
14Fanconi anemia pathway_Homo sapiens_hsa034602.35387758
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.30317399
16mRNA surveillance pathway_Homo sapiens_hsa030152.24584052
17Protein export_Homo sapiens_hsa030602.19116738
18Pyrimidine metabolism_Homo sapiens_hsa002402.11806286
19Non-homologous end-joining_Homo sapiens_hsa034502.10494848
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.03075230
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.94482881
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.88426306
23RNA degradation_Homo sapiens_hsa030181.83032268
24Cysteine and methionine metabolism_Homo sapiens_hsa002701.81310727
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.78966757
26Selenocompound metabolism_Homo sapiens_hsa004501.75984429
27Carbon metabolism_Homo sapiens_hsa012001.71289239
28Systemic lupus erythematosus_Homo sapiens_hsa053221.64460676
29Ribosome_Homo sapiens_hsa030101.59786082
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57976325
31Biosynthesis of amino acids_Homo sapiens_hsa012301.47011953
32Pyruvate metabolism_Homo sapiens_hsa006201.46542430
33Propanoate metabolism_Homo sapiens_hsa006401.40701416
34Basal transcription factors_Homo sapiens_hsa030221.39828250
35Butanoate metabolism_Homo sapiens_hsa006501.37391171
36Purine metabolism_Homo sapiens_hsa002301.22337495
37Steroid biosynthesis_Homo sapiens_hsa001001.20876611
38Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17127011
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.14987265
40Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.12885790
41p53 signaling pathway_Homo sapiens_hsa041151.12654801
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.04669763
43Drug metabolism - other enzymes_Homo sapiens_hsa009831.01329697
44Oxidative phosphorylation_Homo sapiens_hsa001901.01055071
45Caffeine metabolism_Homo sapiens_hsa002320.96933546
46Nitrogen metabolism_Homo sapiens_hsa009100.93315163
47Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91982342
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.90432220
49Oocyte meiosis_Homo sapiens_hsa041140.86123843
50Fatty acid degradation_Homo sapiens_hsa000710.84530821
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79078501
52Epstein-Barr virus infection_Homo sapiens_hsa051690.78801184
53Viral carcinogenesis_Homo sapiens_hsa052030.76131227
54Fatty acid elongation_Homo sapiens_hsa000620.75783177
55Lysine degradation_Homo sapiens_hsa003100.75635593
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67985605
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65862424
58Phototransduction_Homo sapiens_hsa047440.63502739
59Cyanoamino acid metabolism_Homo sapiens_hsa004600.61850624
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60450628
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.59942191
62Circadian rhythm_Homo sapiens_hsa047100.59512081
63Vitamin B6 metabolism_Homo sapiens_hsa007500.56513131
64Herpes simplex infection_Homo sapiens_hsa051680.52523488
65Taste transduction_Homo sapiens_hsa047420.52209085
66Fatty acid biosynthesis_Homo sapiens_hsa000610.51193658
67HTLV-I infection_Homo sapiens_hsa051660.50832959
68Pentose phosphate pathway_Homo sapiens_hsa000300.50020996
69Huntingtons disease_Homo sapiens_hsa050160.49387306
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.49339424
71Alzheimers disease_Homo sapiens_hsa050100.47830115
72Arginine and proline metabolism_Homo sapiens_hsa003300.46896274
73Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45170010
74Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44723878
75Folate biosynthesis_Homo sapiens_hsa007900.44302699
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.44286886
77N-Glycan biosynthesis_Homo sapiens_hsa005100.43922191
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.43773061
79Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.42450282
80Arginine biosynthesis_Homo sapiens_hsa002200.42380821
81Fatty acid metabolism_Homo sapiens_hsa012120.39543475
82Glucagon signaling pathway_Homo sapiens_hsa049220.39116888
83Nicotine addiction_Homo sapiens_hsa050330.38900717
84Galactose metabolism_Homo sapiens_hsa000520.38039224
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.37770217
86Metabolic pathways_Homo sapiens_hsa011000.36972064
87beta-Alanine metabolism_Homo sapiens_hsa004100.36239192
88MicroRNAs in cancer_Homo sapiens_hsa052060.35991467
89Regulation of autophagy_Homo sapiens_hsa041400.35565966
90Thyroid cancer_Homo sapiens_hsa052160.35205673
91Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34624376
92Linoleic acid metabolism_Homo sapiens_hsa005910.34566699
93ABC transporters_Homo sapiens_hsa020100.34426702
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34132014
95Cardiac muscle contraction_Homo sapiens_hsa042600.33292510
96Alcoholism_Homo sapiens_hsa050340.33047360
97Parkinsons disease_Homo sapiens_hsa050120.32531203
98Peroxisome_Homo sapiens_hsa041460.32055752
99Vitamin digestion and absorption_Homo sapiens_hsa049770.31468294
100Adherens junction_Homo sapiens_hsa045200.30439832
101Retinol metabolism_Homo sapiens_hsa008300.30271847
102Central carbon metabolism in cancer_Homo sapiens_hsa052300.30175176
103Fat digestion and absorption_Homo sapiens_hsa049750.29198012
104Olfactory transduction_Homo sapiens_hsa047400.28231552
105HIF-1 signaling pathway_Homo sapiens_hsa040660.28134297
106Ether lipid metabolism_Homo sapiens_hsa005650.27585747
107Fructose and mannose metabolism_Homo sapiens_hsa000510.26883018
108Glutathione metabolism_Homo sapiens_hsa004800.25522219
109Tyrosine metabolism_Homo sapiens_hsa003500.25280393
110Phenylalanine metabolism_Homo sapiens_hsa003600.24344997
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23662213
112Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.23124244
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.22815795
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21445444
115Wnt signaling pathway_Homo sapiens_hsa043100.21113428
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.19891120
117mTOR signaling pathway_Homo sapiens_hsa041500.19441159
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18480153
119Small cell lung cancer_Homo sapiens_hsa052220.18002502
120Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.17873803
121Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.17531633
122Hedgehog signaling pathway_Homo sapiens_hsa043400.16023965
123Tryptophan metabolism_Homo sapiens_hsa003800.15580643
124Tight junction_Homo sapiens_hsa045300.15432702
125Legionellosis_Homo sapiens_hsa051340.14355033
126Dilated cardiomyopathy_Homo sapiens_hsa054140.13862944
127Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.13615034
128Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.12643147
129Endometrial cancer_Homo sapiens_hsa052130.12280802
130Hippo signaling pathway_Homo sapiens_hsa043900.09846857
131Antigen processing and presentation_Homo sapiens_hsa046120.09451897
132Basal cell carcinoma_Homo sapiens_hsa052170.08840635
133TGF-beta signaling pathway_Homo sapiens_hsa043500.08327147
134FoxO signaling pathway_Homo sapiens_hsa040680.07553778

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