

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of interleukin-12 production (GO:0032695) | 5.23085479 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.09999413 |
| 3 | negative regulation of cell killing (GO:0031342) | 4.99570501 |
| 4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.99570501 |
| 5 | response to peptidoglycan (GO:0032494) | 4.67110221 |
| 6 | cellular response to type I interferon (GO:0071357) | 4.30316980 |
| 7 | type I interferon signaling pathway (GO:0060337) | 4.30316980 |
| 8 | macrophage activation involved in immune response (GO:0002281) | 4.26166840 |
| 9 | response to type I interferon (GO:0034340) | 4.24524114 |
| 10 | modulation by symbiont of host immune response (GO:0052553) | 4.07534010 |
| 11 | positive regulation by symbiont of host defense response (GO:0052509) | 4.07534010 |
| 12 | modulation by symbiont of host defense response (GO:0052031) | 4.07534010 |
| 13 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.07534010 |
| 14 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.07534010 |
| 15 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.07534010 |
| 16 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.04901548 |
| 17 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.04470928 |
| 18 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.02379219 |
| 19 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.97558799 |
| 20 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.96566462 |
| 21 | neutrophil activation involved in immune response (GO:0002283) | 3.92094909 |
| 22 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.87193234 |
| 23 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.83023555 |
| 24 | regulation of interferon-alpha production (GO:0032647) | 3.82956317 |
| 25 | immunoglobulin mediated immune response (GO:0016064) | 3.82822614 |
| 26 | defense response to protozoan (GO:0042832) | 3.82401991 |
| 27 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.80718439 |
| 28 | leukocyte aggregation (GO:0070486) | 3.77225750 |
| 29 | regulation of gamma-delta T cell activation (GO:0046643) | 3.77203854 |
| 30 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.76907176 |
| 31 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.74926940 |
| 32 | regulation of chronic inflammatory response (GO:0002676) | 3.71721350 |
| 33 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.71452591 |
| 34 | response to protozoan (GO:0001562) | 3.63208912 |
| 35 | regulation of regulatory T cell differentiation (GO:0045589) | 3.62908941 |
| 36 | detection of other organism (GO:0098543) | 3.60206752 |
| 37 | regulation of T cell tolerance induction (GO:0002664) | 3.60176140 |
| 38 | detection of molecule of bacterial origin (GO:0032490) | 3.58693670 |
| 39 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.53053825 |
| 40 | germinal center formation (GO:0002467) | 3.52680852 |
| 41 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.52067853 |
| 42 | granulocyte activation (GO:0036230) | 3.51202039 |
| 43 | positive regulation of interferon-alpha production (GO:0032727) | 3.46007561 |
| 44 | response to muramyl dipeptide (GO:0032495) | 3.44730100 |
| 45 | negative regulation of T cell mediated immunity (GO:0002710) | 3.44345696 |
| 46 | T-helper 1 type immune response (GO:0042088) | 3.40757062 |
| 47 | NIK/NF-kappaB signaling (GO:0038061) | 3.40123498 |
| 48 | T cell migration (GO:0072678) | 3.36774889 |
| 49 | neutrophil activation (GO:0042119) | 3.32743081 |
| 50 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.29816442 |
| 51 | regulation of fever generation (GO:0031620) | 3.29107832 |
| 52 | regulation of tolerance induction (GO:0002643) | 3.26017844 |
| 53 | positive regulation of type 2 immune response (GO:0002830) | 3.24828781 |
| 54 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.24828370 |
| 55 | detection of bacterium (GO:0016045) | 3.24454464 |
| 56 | response to interleukin-15 (GO:0070672) | 3.23438634 |
| 57 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.22960875 |
| 58 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.21539936 |
| 59 | regulation of interleukin-12 production (GO:0032655) | 3.19924902 |
| 60 | myeloid dendritic cell differentiation (GO:0043011) | 3.19063628 |
| 61 | negative regulation of viral genome replication (GO:0045071) | 3.18435680 |
| 62 | detection of external biotic stimulus (GO:0098581) | 3.16036561 |
| 63 | macrophage activation (GO:0042116) | 3.15648739 |
| 64 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.14454381 |
| 65 | positive regulation of tolerance induction (GO:0002645) | 3.13466350 |
| 66 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.12286996 |
| 67 | positive regulation of heat generation (GO:0031652) | 3.12198862 |
| 68 | cellular response to interleukin-15 (GO:0071350) | 3.09424164 |
| 69 | regulation of podosome assembly (GO:0071801) | 3.09384015 |
| 70 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.09333443 |
| 71 | tolerance induction (GO:0002507) | 3.07574354 |
| 72 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.06536397 |
| 73 | myeloid cell activation involved in immune response (GO:0002275) | 3.06283998 |
| 74 | microglial cell activation (GO:0001774) | 3.04401449 |
| 75 | interferon-gamma secretion (GO:0072643) | 3.03559138 |
| 76 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.03354944 |
| 77 | cellular extravasation (GO:0045123) | 3.02089052 |
| 78 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.01155330 |
| 79 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.00361641 |
| 80 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.99162148 |
| 81 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.97246817 |
| 82 | B cell mediated immunity (GO:0019724) | 2.97246078 |
| 83 | regulation of T-helper cell differentiation (GO:0045622) | 2.97214986 |
| 84 | positive regulation of acute inflammatory response (GO:0002675) | 2.95201831 |
| 85 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.94314079 |
| 86 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.94274826 |
| 87 | regulation of vitamin metabolic process (GO:0030656) | 2.94042429 |
| 88 | positive regulation of interleukin-17 production (GO:0032740) | 2.93555302 |
| 89 | positive regulation of defense response to virus by host (GO:0002230) | 2.93542542 |
| 90 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.92180930 |
| 91 | detection of biotic stimulus (GO:0009595) | 2.91528051 |
| 92 | myeloid dendritic cell activation (GO:0001773) | 2.91288528 |
| 93 | negative regulation of interleukin-6 production (GO:0032715) | 2.88150364 |
| 94 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.88057998 |
| 95 | lymphocyte chemotaxis (GO:0048247) | 2.87928426 |
| 96 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.87701134 |
| 97 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.87423826 |
| 98 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.87070310 |
| 99 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.86986480 |
| 100 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.86932277 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.82711632 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.46317912 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.14719844 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.50830329 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.46772708 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.33703354 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.67663421 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.59805370 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.20908698 |
| 10 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.20712435 |
| 11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.12958374 |
| 12 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.00377353 |
| 13 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.88586801 |
| 14 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.80492764 |
| 15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.62291509 |
| 16 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.50119389 |
| 17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.46968099 |
| 18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.40602722 |
| 19 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.36646366 |
| 20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.29061446 |
| 21 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.16306518 |
| 22 | MYB_26560356_Chip-Seq_TH2_Human | 2.14172516 |
| 23 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.13056025 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.12230795 |
| 25 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.06170991 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 2.02945983 |
| 27 | SPI1_23127762_ChIP-Seq_K562_Human | 2.02734913 |
| 28 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.00929213 |
| 29 | GATA1_22025678_ChIP-Seq_K562_Human | 2.00320498 |
| 30 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.97740566 |
| 31 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.97300347 |
| 32 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.77376090 |
| 33 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.75794568 |
| 34 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.73803884 |
| 35 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.72700889 |
| 36 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.70185481 |
| 37 | MYB_26560356_Chip-Seq_TH1_Human | 1.68091203 |
| 38 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.61964677 |
| 39 | UTX_26944678_Chip-Seq_JUKART_Human | 1.61515023 |
| 40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.60470880 |
| 41 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.51116439 |
| 42 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.49892106 |
| 43 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.49784192 |
| 44 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.45774753 |
| 45 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.45733836 |
| 46 | MAF_26560356_Chip-Seq_TH2_Human | 1.45200833 |
| 47 | GATA3_26560356_Chip-Seq_TH2_Human | 1.42953247 |
| 48 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.38643034 |
| 49 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38534797 |
| 50 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.36791989 |
| 51 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36113007 |
| 52 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.35960057 |
| 53 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33133515 |
| 54 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.29411775 |
| 55 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24925608 |
| 56 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24003222 |
| 57 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.20750130 |
| 58 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16446921 |
| 59 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.16203354 |
| 60 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.15978689 |
| 61 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14736289 |
| 62 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14376213 |
| 63 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.12983928 |
| 64 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07072982 |
| 65 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.06795697 |
| 66 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05598315 |
| 67 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.04303589 |
| 68 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.02768006 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99967780 |
| 70 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.99910470 |
| 71 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99009427 |
| 72 | MYC_22102868_ChIP-Seq_BL_Human | 0.97539595 |
| 73 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.97154961 |
| 74 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.95900321 |
| 75 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.95258116 |
| 76 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.94951797 |
| 77 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91359301 |
| 78 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88243773 |
| 79 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.88102185 |
| 80 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.85736211 |
| 81 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.85392963 |
| 82 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.85165958 |
| 83 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.82094464 |
| 84 | GATA1_19941826_ChIP-Seq_K562_Human | 0.79125621 |
| 85 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78778275 |
| 86 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76801236 |
| 87 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.74863150 |
| 88 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.74521043 |
| 89 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.74521043 |
| 90 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.74521043 |
| 91 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.71324467 |
| 92 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.69331517 |
| 93 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.69253166 |
| 94 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.68782834 |
| 95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.68207781 |
| 96 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.67675583 |
| 97 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.66783478 |
| 98 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.62555656 |
| 99 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.61591033 |
| 100 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.60636264 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 5.65680385 |
| 2 | MP0003724_increased_susceptibility_to | 4.93601386 |
| 3 | MP0003436_decreased_susceptibility_to | 3.99110040 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.79748269 |
| 5 | MP0009785_altered_susceptibility_to | 3.51663514 |
| 6 | MP0006082_CNS_inflammation | 3.44054730 |
| 7 | MP0005671_abnormal_response_to | 3.43269177 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 3.23800140 |
| 9 | MP0005000_abnormal_immune_tolerance | 3.05573391 |
| 10 | MP0001790_abnormal_immune_system | 2.91055666 |
| 11 | MP0005387_immune_system_phenotype | 2.91055666 |
| 12 | MP0005025_abnormal_response_to | 2.86862865 |
| 13 | MP0002419_abnormal_innate_immunity | 2.80814051 |
| 14 | MP0001800_abnormal_humoral_immune | 2.77319339 |
| 15 | MP0004510_myositis | 2.66653695 |
| 16 | MP0003300_gastrointestinal_ulcer | 2.66287222 |
| 17 | MP0002723_abnormal_immune_serum | 2.62373085 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.46948497 |
| 19 | MP0009764_decreased_sensitivity_to | 2.33712547 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.25746598 |
| 21 | MP0001819_abnormal_immune_cell | 2.24991383 |
| 22 | MP0000685_abnormal_immune_system | 2.24356208 |
| 23 | MP0001533_abnormal_skeleton_physiology | 2.22918417 |
| 24 | MP0004947_skin_inflammation | 2.09831042 |
| 25 | MP0001853_heart_inflammation | 2.03434842 |
| 26 | MP0010155_abnormal_intestine_physiology | 1.97478502 |
| 27 | MP0002405_respiratory_system_inflammati | 1.86857995 |
| 28 | MP0003075_altered_response_to | 1.85452785 |
| 29 | MP0003763_abnormal_thymus_physiology | 1.84992438 |
| 30 | MP0001845_abnormal_inflammatory_respons | 1.82224433 |
| 31 | MP0008004_abnormal_stomach_pH | 1.77812036 |
| 32 | MP0009278_abnormal_bone_marrow | 1.74218574 |
| 33 | MP0008469_abnormal_protein_level | 1.69265657 |
| 34 | MP0000716_abnormal_immune_system | 1.65763031 |
| 35 | MP0009333_abnormal_splenocyte_physiolog | 1.60670808 |
| 36 | MP0002398_abnormal_bone_marrow | 1.54211660 |
| 37 | MP0000465_gastrointestinal_hemorrhage | 1.47027535 |
| 38 | MP0002332_abnormal_exercise_endurance | 1.45838223 |
| 39 | MP0003448_altered_tumor_morphology | 1.42015721 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.40652606 |
| 41 | MP0005058_abnormal_lysosome_morphology | 1.32831161 |
| 42 | MP0000343_altered_response_to | 1.30695008 |
| 43 | MP0005310_abnormal_salivary_gland | 1.27245167 |
| 44 | MP0005167_abnormal_blood-brain_barrier | 1.25355753 |
| 45 | MP0005166_decreased_susceptibility_to | 1.24579317 |
| 46 | MP0002429_abnormal_blood_cell | 1.22601605 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.22000870 |
| 48 | MP0002998_abnormal_bone_remodeling | 1.21615398 |
| 49 | MP0000858_altered_metastatic_potential | 1.21263331 |
| 50 | MP0005464_abnormal_platelet_physiology | 1.21198033 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.20051848 |
| 52 | MP0002722_abnormal_immune_system | 1.19403595 |
| 53 | MP0005397_hematopoietic_system_phenotyp | 1.16605556 |
| 54 | MP0001545_abnormal_hematopoietic_system | 1.16605556 |
| 55 | MP0005164_abnormal_response_to | 1.13968847 |
| 56 | MP0003453_abnormal_keratinocyte_physiol | 1.13854921 |
| 57 | MP0003172_abnormal_lysosome_physiology | 1.09225633 |
| 58 | MP0002138_abnormal_hepatobiliary_system | 1.08365999 |
| 59 | MP0000604_amyloidosis | 1.08136561 |
| 60 | MP0005451_abnormal_body_composition | 1.07467937 |
| 61 | MP0000569_abnormal_digit_pigmentation | 1.06882300 |
| 62 | MP0003866_abnormal_defecation | 1.06672942 |
| 63 | MP0004883_abnormal_blood_vessel | 1.01871336 |
| 64 | MP0001663_abnormal_digestive_system | 0.99376752 |
| 65 | MP0003806_abnormal_nucleotide_metabolis | 0.99220901 |
| 66 | MP0003195_calcinosis | 0.99087543 |
| 67 | MP0009763_increased_sensitivity_to | 0.98790660 |
| 68 | MP0003045_fibrosis | 0.97961898 |
| 69 | MP0008260_abnormal_autophagy | 0.96146284 |
| 70 | MP0000703_abnormal_thymus_morphology | 0.94353413 |
| 71 | MP0003690_abnormal_glial_cell | 0.93310176 |
| 72 | MP0003183_abnormal_peptide_metabolism | 0.92427863 |
| 73 | MP0009765_abnormal_xenobiotic_induced | 0.92078310 |
| 74 | MP0003828_pulmonary_edema | 0.91031728 |
| 75 | MP0005390_skeleton_phenotype | 0.90388781 |
| 76 | MP0002139_abnormal_hepatobiliary_system | 0.88971301 |
| 77 | MP0005535_abnormal_body_temperature | 0.86887935 |
| 78 | MP0001873_stomach_inflammation | 0.86762370 |
| 79 | MP0003646_muscle_fatigue | 0.81500900 |
| 80 | MP0006054_spinal_hemorrhage | 0.81079972 |
| 81 | MP0003091_abnormal_cell_migration | 0.80101544 |
| 82 | MP0002132_abnormal_respiratory_system | 0.77715493 |
| 83 | MP0009840_abnormal_foam_cell | 0.76328372 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.74090776 |
| 85 | MP0003656_abnormal_erythrocyte_physiolo | 0.71070842 |
| 86 | MP0002933_joint_inflammation | 0.67632024 |
| 87 | MP0001851_eye_inflammation | 0.67563156 |
| 88 | MP0002254_reproductive_system_inflammat | 0.67544432 |
| 89 | MP0004381_abnormal_hair_follicle | 0.65996928 |
| 90 | MP0004808_abnormal_hematopoietic_stem | 0.64426135 |
| 91 | MP0000249_abnormal_blood_vessel | 0.60359195 |
| 92 | MP0005381_digestive/alimentary_phenotyp | 0.58839763 |
| 93 | MP0008874_decreased_physiological_sensi | 0.58549096 |
| 94 | MP0000490_abnormal_crypts_of | 0.55922706 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.55325190 |
| 96 | MP0002006_tumorigenesis | 0.52877600 |
| 97 | MP0003795_abnormal_bone_structure | 0.52247501 |
| 98 | MP0005266_abnormal_metabolism | 0.50655921 |
| 99 | MP0000920_abnormal_myelination | 0.50092307 |
| 100 | MP0003221_abnormal_cardiomyocyte_apopto | 0.49412117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Optic neuritis (HP:0100653) | 6.71351701 |
| 2 | Retrobulbar optic neuritis (HP:0100654) | 6.71351701 |
| 3 | Orchitis (HP:0100796) | 6.47710861 |
| 4 | Myositis (HP:0100614) | 6.11739018 |
| 5 | Stomatitis (HP:0010280) | 5.96272162 |
| 6 | Eczematoid dermatitis (HP:0000976) | 5.64892341 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 5.20831123 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.18595113 |
| 9 | Recurrent abscess formation (HP:0002722) | 4.82261087 |
| 10 | Keratoconjunctivitis sicca (HP:0001097) | 4.70256972 |
| 11 | Abnormality of macrophages (HP:0004311) | 4.69019200 |
| 12 | Keratoconjunctivitis (HP:0001096) | 4.28319659 |
| 13 | Vasculitis (HP:0002633) | 4.08482657 |
| 14 | Mediastinal lymphadenopathy (HP:0100721) | 4.05979981 |
| 15 | Gastrointestinal infarctions (HP:0005244) | 3.81030911 |
| 16 | Abnormality of glycolipid metabolism (HP:0010969) | 3.80394737 |
| 17 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.80394737 |
| 18 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.80394737 |
| 19 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.80285567 |
| 20 | T lymphocytopenia (HP:0005403) | 3.77764962 |
| 21 | Abnormality of T cell number (HP:0011839) | 3.64645497 |
| 22 | Increased IgM level (HP:0003496) | 3.64521744 |
| 23 | Pulmonary infiltrates (HP:0002113) | 3.64491225 |
| 24 | Recurrent fungal infections (HP:0002841) | 3.61432490 |
| 25 | Gangrene (HP:0100758) | 3.61355845 |
| 26 | Encephalitis (HP:0002383) | 3.61173705 |
| 27 | Hemoptysis (HP:0002105) | 3.45233773 |
| 28 | Meningitis (HP:0001287) | 3.44871116 |
| 29 | Recurrent skin infections (HP:0001581) | 3.37715430 |
| 30 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.35089216 |
| 31 | Chronic obstructive pulmonary disease (HP:0006510) | 3.22717770 |
| 32 | Obstructive lung disease (HP:0006536) | 3.22717770 |
| 33 | Autoimmune thrombocytopenia (HP:0001973) | 3.21476280 |
| 34 | Arterial thrombosis (HP:0004420) | 3.08669826 |
| 35 | Leukocytosis (HP:0001974) | 3.00442361 |
| 36 | Autoimmune hemolytic anemia (HP:0001890) | 2.99178676 |
| 37 | Systemic lupus erythematosus (HP:0002725) | 2.91738687 |
| 38 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.91644025 |
| 39 | Recurrent cutaneous fungal infections (HP:0011370) | 2.91644025 |
| 40 | Increased IgE level (HP:0003212) | 2.90864497 |
| 41 | Anorexia (HP:0002039) | 2.87161494 |
| 42 | Pulmonary embolism (HP:0002204) | 2.86679908 |
| 43 | Abnormality of the pleura (HP:0002103) | 2.83224185 |
| 44 | Recurrent viral infections (HP:0004429) | 2.81735154 |
| 45 | Chest pain (HP:0100749) | 2.76959710 |
| 46 | Episodic fever (HP:0001954) | 2.73076951 |
| 47 | Abnormality of T cells (HP:0002843) | 2.70538470 |
| 48 | Urticaria (HP:0001025) | 2.69456143 |
| 49 | Stomach cancer (HP:0012126) | 2.67249161 |
| 50 | Disinhibition (HP:0000734) | 2.67192433 |
| 51 | Gingivitis (HP:0000230) | 2.65322946 |
| 52 | Spontaneous hematomas (HP:0007420) | 2.50258330 |
| 53 | Polyneuropathy (HP:0001271) | 2.49987331 |
| 54 | Hypergammaglobulinemia (HP:0010702) | 2.48799521 |
| 55 | Recurrent bronchitis (HP:0002837) | 2.44249962 |
| 56 | Alveolar cell carcinoma (HP:0006519) | 2.43825369 |
| 57 | Abnormality of the pericardium (HP:0001697) | 2.41585191 |
| 58 | Parakeratosis (HP:0001036) | 2.40931122 |
| 59 | Amyloidosis (HP:0011034) | 2.36676145 |
| 60 | Eosinophilia (HP:0001880) | 2.35837222 |
| 61 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.32750606 |
| 62 | Peritonitis (HP:0002586) | 2.32120734 |
| 63 | Loss of speech (HP:0002371) | 2.30497736 |
| 64 | Chronic otitis media (HP:0000389) | 2.28141232 |
| 65 | Glomerulopathy (HP:0100820) | 2.26893826 |
| 66 | Vertigo (HP:0002321) | 2.26502549 |
| 67 | Keratitis (HP:0000491) | 2.26384658 |
| 68 | Purpura (HP:0000979) | 2.25029537 |
| 69 | Dysostosis multiplex (HP:0000943) | 2.24491075 |
| 70 | Acne (HP:0001061) | 2.24073225 |
| 71 | Joint swelling (HP:0001386) | 2.23314725 |
| 72 | Granulocytopenia (HP:0001913) | 2.21729998 |
| 73 | Increased serum ferritin (HP:0003281) | 2.19856382 |
| 74 | Petechiae (HP:0000967) | 2.19762430 |
| 75 | Hepatosplenomegaly (HP:0001433) | 2.15771299 |
| 76 | Abnormality of eosinophils (HP:0001879) | 2.14815520 |
| 77 | Vacuolated lymphocytes (HP:0001922) | 2.13291577 |
| 78 | IgG deficiency (HP:0004315) | 2.11819008 |
| 79 | Lymphopenia (HP:0001888) | 2.10325990 |
| 80 | Interstitial pulmonary disease (HP:0006530) | 2.08773908 |
| 81 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.08247852 |
| 82 | Abnormality of the endocardium (HP:0004306) | 2.04458502 |
| 83 | Gastrointestinal stroma tumor (HP:0100723) | 2.04157019 |
| 84 | Inflammation of the large intestine (HP:0002037) | 2.03390957 |
| 85 | Abnormality of B cell number (HP:0010975) | 2.01914057 |
| 86 | Panhypogammaglobulinemia (HP:0003139) | 2.01626104 |
| 87 | Arthralgia (HP:0002829) | 2.00470482 |
| 88 | Gingival bleeding (HP:0000225) | 1.99190686 |
| 89 | Severe combined immunodeficiency (HP:0004430) | 1.98882153 |
| 90 | Increased cerebral lipofuscin (HP:0011813) | 1.98488313 |
| 91 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.98350205 |
| 92 | Colitis (HP:0002583) | 1.95361571 |
| 93 | Abnormality of T cell physiology (HP:0011840) | 1.94878151 |
| 94 | Prolonged bleeding time (HP:0003010) | 1.94649672 |
| 95 | Abnormality of iron homeostasis (HP:0011031) | 1.93319554 |
| 96 | Pustule (HP:0200039) | 1.90889333 |
| 97 | Epistaxis (HP:0000421) | 1.89662420 |
| 98 | Basal ganglia calcification (HP:0002135) | 1.88946196 |
| 99 | Abnormality of the peritoneum (HP:0002585) | 1.88771754 |
| 100 | Thrombophlebitis (HP:0004418) | 1.88704456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRAK4 | 3.92622387 |
| 2 | TXK | 3.83204464 |
| 3 | RIPK4 | 3.76740853 |
| 4 | MAP4K1 | 3.35902888 |
| 5 | MAP3K14 | 2.78136616 |
| 6 | IRAK3 | 2.74808745 |
| 7 | TYK2 | 2.67658943 |
| 8 | IKBKE | 2.61508672 |
| 9 | CSK | 2.52480543 |
| 10 | TBK1 | 2.38811313 |
| 11 | GRK7 | 2.33106789 |
| 12 | BLK | 2.31172079 |
| 13 | MAP2K3 | 2.24879461 |
| 14 | JAK3 | 2.10077654 |
| 15 | SIK3 | 2.09816381 |
| 16 | TAOK1 | 2.03628768 |
| 17 | IKBKB | 1.90467055 |
| 18 | MATK | 1.89577718 |
| 19 | IRAK1 | 1.88362828 |
| 20 | ZAP70 | 1.88340885 |
| 21 | BMPR2 | 1.87258656 |
| 22 | FGR | 1.84215056 |
| 23 | TAOK2 | 1.83944841 |
| 24 | MAP3K3 | 1.76867233 |
| 25 | MAP3K11 | 1.76425515 |
| 26 | RIPK1 | 1.69375503 |
| 27 | ERN1 | 1.63378257 |
| 28 | PRPF4B | 1.56463623 |
| 29 | SIK2 | 1.54536790 |
| 30 | JAK1 | 1.50511694 |
| 31 | TAOK3 | 1.49830154 |
| 32 | FES | 1.45395570 |
| 33 | IRAK2 | 1.42226712 |
| 34 | SYK | 1.41288927 |
| 35 | EPHB1 | 1.40204049 |
| 36 | TYRO3 | 1.29647023 |
| 37 | LYN | 1.27593378 |
| 38 | JAK2 | 1.27078331 |
| 39 | SIK1 | 1.24015552 |
| 40 | HCK | 1.22982293 |
| 41 | MARK3 | 1.22840828 |
| 42 | TNK2 | 1.16941011 |
| 43 | LCK | 1.13265536 |
| 44 | BTK | 1.13146017 |
| 45 | DDR2 | 1.12655116 |
| 46 | CHUK | 1.11869925 |
| 47 | EPHA3 | 1.11601344 |
| 48 | FGFR4 | 1.08815802 |
| 49 | TESK2 | 1.07744161 |
| 50 | MAP3K13 | 1.06847002 |
| 51 | MAP3K1 | 1.05716408 |
| 52 | ITK | 1.03873318 |
| 53 | CSF1R | 1.00122402 |
| 54 | MOS | 0.95397473 |
| 55 | TGFBR2 | 0.91816997 |
| 56 | GRK6 | 0.88758452 |
| 57 | KIT | 0.85445001 |
| 58 | MAP3K5 | 0.84095589 |
| 59 | MAP2K6 | 0.80945440 |
| 60 | CDC42BPA | 0.79735294 |
| 61 | ADRBK2 | 0.77963126 |
| 62 | DYRK1B | 0.74964615 |
| 63 | NME2 | 0.72924705 |
| 64 | FGFR3 | 0.71091836 |
| 65 | YES1 | 0.69342856 |
| 66 | PIM2 | 0.67842781 |
| 67 | PIM1 | 0.66128988 |
| 68 | DYRK3 | 0.66027632 |
| 69 | STK10 | 0.64708439 |
| 70 | TEC | 0.58921491 |
| 71 | MARK2 | 0.55816261 |
| 72 | HIPK2 | 0.52292896 |
| 73 | FYN | 0.50464851 |
| 74 | MAPK15 | 0.48710921 |
| 75 | PDK1 | 0.47491910 |
| 76 | NLK | 0.46664618 |
| 77 | CAMKK2 | 0.45268455 |
| 78 | PRKCQ | 0.43983330 |
| 79 | ACVR1B | 0.39718358 |
| 80 | MAPK4 | 0.29642870 |
| 81 | INSR | 0.29216873 |
| 82 | MAPKAPK2 | 0.23821474 |
| 83 | PDPK1 | 0.23692924 |
| 84 | KSR2 | 0.21519660 |
| 85 | CLK1 | 0.20848111 |
| 86 | LRRK2 | 0.19857198 |
| 87 | CAMKK1 | 0.18891439 |
| 88 | KSR1 | 0.17318293 |
| 89 | PRKCD | 0.17160417 |
| 90 | PDGFRB | 0.16897036 |
| 91 | PASK | 0.16764772 |
| 92 | ABL1 | 0.16397250 |
| 93 | EIF2AK2 | 0.16391796 |
| 94 | PRKD2 | 0.15622396 |
| 95 | EGFR | 0.14637906 |
| 96 | PTK2B | 0.14532485 |
| 97 | PIK3CG | 0.14135475 |
| 98 | RPS6KA6 | 0.13687920 |
| 99 | PRKCZ | 0.13127006 |
| 100 | CDK6 | 0.12482859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Allograft rejection_Homo sapiens_hsa05330 | 2.93258763 |
| 2 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.87013767 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.86486878 |
| 4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.86486279 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.81131041 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.72597268 |
| 7 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.54584331 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.53725986 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.50837190 |
| 10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.41289186 |
| 11 | Malaria_Homo sapiens_hsa05144 | 2.37854129 |
| 12 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.23518349 |
| 13 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.17421996 |
| 14 | Legionellosis_Homo sapiens_hsa05134 | 2.16202907 |
| 15 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.13078852 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.12592702 |
| 17 | Asthma_Homo sapiens_hsa05310 | 2.12367122 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.11109067 |
| 19 | Measles_Homo sapiens_hsa05162 | 2.09730654 |
| 20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.06105257 |
| 21 | Tuberculosis_Homo sapiens_hsa05152 | 2.00031502 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.96664904 |
| 23 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.95859498 |
| 24 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.81458822 |
| 25 | Influenza A_Homo sapiens_hsa05164 | 1.80271228 |
| 26 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.75512529 |
| 27 | Pertussis_Homo sapiens_hsa05133 | 1.74407923 |
| 28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.73163013 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71685207 |
| 30 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.71504188 |
| 31 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.65172742 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.56578024 |
| 33 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.56200486 |
| 34 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.52208098 |
| 35 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.49184462 |
| 36 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.43382911 |
| 37 | Salmonella infection_Homo sapiens_hsa05132 | 1.43199412 |
| 38 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.27576154 |
| 39 | Hepatitis C_Homo sapiens_hsa05160 | 1.27519632 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.22632792 |
| 41 | Hepatitis B_Homo sapiens_hsa05161 | 1.16996317 |
| 42 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.14604482 |
| 43 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.14326367 |
| 44 | Other glycan degradation_Homo sapiens_hsa00511 | 1.11653311 |
| 45 | Phagosome_Homo sapiens_hsa04145 | 1.05470876 |
| 46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.03362790 |
| 47 | Apoptosis_Homo sapiens_hsa04210 | 0.93370664 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 0.92399908 |
| 49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.90401593 |
| 50 | Lysosome_Homo sapiens_hsa04142 | 0.90206587 |
| 51 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.90004553 |
| 52 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.87600169 |
| 53 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.84851497 |
| 54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.73796643 |
| 55 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.73479366 |
| 56 | Prion diseases_Homo sapiens_hsa05020 | 0.73363704 |
| 57 | Amoebiasis_Homo sapiens_hsa05146 | 0.72814619 |
| 58 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.72477187 |
| 59 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.72079767 |
| 60 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59159086 |
| 61 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.58979080 |
| 62 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.56362503 |
| 63 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.55651275 |
| 64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.53033290 |
| 65 | HTLV-I infection_Homo sapiens_hsa05166 | 0.52681247 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51642342 |
| 67 | Platelet activation_Homo sapiens_hsa04611 | 0.48975287 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.48888459 |
| 69 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.46158781 |
| 70 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45414116 |
| 71 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.45201906 |
| 72 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.43459849 |
| 73 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.42788822 |
| 74 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.41655186 |
| 75 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.37482679 |
| 76 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.35111438 |
| 77 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.34363852 |
| 78 | Insulin resistance_Homo sapiens_hsa04931 | 0.32332636 |
| 79 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.32132095 |
| 80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.32110341 |
| 81 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.31604240 |
| 82 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.31020576 |
| 83 | Endocytosis_Homo sapiens_hsa04144 | 0.28914571 |
| 84 | Bladder cancer_Homo sapiens_hsa05219 | 0.28475020 |
| 85 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.28342889 |
| 86 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.28209112 |
| 87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.28052372 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.24045570 |
| 89 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.16802329 |
| 90 | Prostate cancer_Homo sapiens_hsa05215 | 0.14354091 |
| 91 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.13573969 |
| 92 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.13478562 |
| 93 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.13460620 |
| 94 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.13407744 |
| 95 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.12953781 |
| 96 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.09653675 |
| 97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.09607565 |
| 98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.09264709 |
| 99 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.08930558 |
| 100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.07869279 |

