

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | behavioral response to nicotine (GO:0035095) | 6.15902260 |
| 2 | DNA deamination (GO:0045006) | 5.05502019 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.97883644 |
| 4 | viral transcription (GO:0019083) | 4.92604606 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.91027174 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.91027174 |
| 7 | ribosomal small subunit biogenesis (GO:0042274) | 4.90541634 |
| 8 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 4.87174281 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.84245837 |
| 10 | translational termination (GO:0006415) | 4.71999451 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.67785259 |
| 12 | cytidine metabolic process (GO:0046087) | 4.28521669 |
| 13 | cytidine catabolic process (GO:0006216) | 4.28521669 |
| 14 | cytidine deamination (GO:0009972) | 4.28521669 |
| 15 | translational elongation (GO:0006414) | 4.20605945 |
| 16 | ribosomal small subunit assembly (GO:0000028) | 4.14910527 |
| 17 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.00889473 |
| 18 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.00889473 |
| 19 | mitochondrial calcium ion transport (GO:0006851) | 3.96232116 |
| 20 | protein neddylation (GO:0045116) | 3.82985793 |
| 21 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.80394911 |
| 22 | protein targeting to ER (GO:0045047) | 3.79808827 |
| 23 | cotranslational protein targeting to membrane (GO:0006613) | 3.76517844 |
| 24 | arachidonic acid secretion (GO:0050482) | 3.70904859 |
| 25 | icosanoid secretion (GO:0032309) | 3.70904859 |
| 26 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.68611241 |
| 27 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.68611241 |
| 28 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.67606600 |
| 29 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.67606600 |
| 30 | nephron epithelium morphogenesis (GO:0072088) | 3.66670971 |
| 31 | nephron tubule morphogenesis (GO:0072078) | 3.66670971 |
| 32 | protein localization to endoplasmic reticulum (GO:0070972) | 3.65757087 |
| 33 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.64112941 |
| 34 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.60229818 |
| 35 | viral life cycle (GO:0019058) | 3.57036829 |
| 36 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.54293521 |
| 37 | protein complex biogenesis (GO:0070271) | 3.49975544 |
| 38 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.48955768 |
| 39 | cellular protein complex disassembly (GO:0043624) | 3.47487657 |
| 40 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.44355847 |
| 41 | chaperone-mediated protein transport (GO:0072321) | 3.35605129 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.35427264 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.35427264 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.35427264 |
| 45 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.33641257 |
| 46 | synaptic transmission, dopaminergic (GO:0001963) | 3.33587818 |
| 47 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.22730940 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.20720740 |
| 49 | electron transport chain (GO:0022900) | 3.16984560 |
| 50 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.14763303 |
| 51 | positive regulation of T cell apoptotic process (GO:0070234) | 3.14707236 |
| 52 | respiratory electron transport chain (GO:0022904) | 3.13017766 |
| 53 | regulation of regulatory T cell differentiation (GO:0045589) | 3.07551159 |
| 54 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.05762228 |
| 55 | protein complex disassembly (GO:0043241) | 3.01346991 |
| 56 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.99061266 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.97850635 |
| 58 | transmission of nerve impulse (GO:0019226) | 2.94843043 |
| 59 | behavioral response to cocaine (GO:0048148) | 2.94379445 |
| 60 | response to pheromone (GO:0019236) | 2.93943123 |
| 61 | cell proliferation in forebrain (GO:0021846) | 2.90419747 |
| 62 | ATP biosynthetic process (GO:0006754) | 2.90037744 |
| 63 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.89665666 |
| 64 | protein-cofactor linkage (GO:0018065) | 2.88895168 |
| 65 | GTP biosynthetic process (GO:0006183) | 2.88487417 |
| 66 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.86170333 |
| 67 | positive regulation of tolerance induction (GO:0002645) | 2.85675345 |
| 68 | icosanoid transport (GO:0071715) | 2.85269133 |
| 69 | fatty acid derivative transport (GO:1901571) | 2.85269133 |
| 70 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85055402 |
| 71 | cellular biogenic amine catabolic process (GO:0042402) | 2.84981489 |
| 72 | amine catabolic process (GO:0009310) | 2.84981489 |
| 73 | macromolecular complex disassembly (GO:0032984) | 2.84030031 |
| 74 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 2.83223127 |
| 75 | cornea development in camera-type eye (GO:0061303) | 2.82441580 |
| 76 | positive regulation of protein homooligomerization (GO:0032464) | 2.81699086 |
| 77 | regulation of neurotransmitter uptake (GO:0051580) | 2.80520890 |
| 78 | sequestering of actin monomers (GO:0042989) | 2.80294240 |
| 79 | positive regulation of respiratory burst (GO:0060267) | 2.79192752 |
| 80 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.78560137 |
| 81 | cellular component biogenesis (GO:0044085) | 2.78280078 |
| 82 | translational initiation (GO:0006413) | 2.77703214 |
| 83 | protein import into peroxisome matrix (GO:0016558) | 2.76277764 |
| 84 | negative regulation of mast cell activation (GO:0033004) | 2.75767820 |
| 85 | intracellular protein transmembrane import (GO:0044743) | 2.74003412 |
| 86 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.73389595 |
| 87 | G-protein coupled receptor internalization (GO:0002031) | 2.72691225 |
| 88 | pattern specification involved in kidney development (GO:0061004) | 2.72159700 |
| 89 | epithelial cilium movement (GO:0003351) | 2.71839807 |
| 90 | grooming behavior (GO:0007625) | 2.70746866 |
| 91 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.64848165 |
| 92 | renal tubule morphogenesis (GO:0061333) | 2.62657712 |
| 93 | translation (GO:0006412) | 2.61628885 |
| 94 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.61588820 |
| 95 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.60585199 |
| 96 | ubiquinone biosynthetic process (GO:0006744) | 2.59969328 |
| 97 | regulation of T cell tolerance induction (GO:0002664) | 2.58202847 |
| 98 | negative regulation of telomere maintenance (GO:0032205) | 2.55279360 |
| 99 | negative regulation by host of viral transcription (GO:0043922) | 2.55240980 |
| 100 | protein targeting to membrane (GO:0006612) | 2.52833890 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.26338722 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.67697491 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.40076040 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.21444322 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.97966665 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.96582936 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.80689736 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.24646407 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.14609995 |
| 10 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.13568204 |
| 11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.05091886 |
| 12 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.99737063 |
| 13 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.99013736 |
| 14 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.95826691 |
| 15 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.90176506 |
| 16 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.87568080 |
| 17 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.81989817 |
| 18 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.78561960 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.77826758 |
| 20 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.76306516 |
| 21 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.63699064 |
| 22 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.60633729 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.60334063 |
| 24 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.58784006 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54175517 |
| 26 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.53422342 |
| 27 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.51885218 |
| 28 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.51227497 |
| 29 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.47734927 |
| 30 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.47564376 |
| 31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.45266460 |
| 32 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.44940679 |
| 33 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.42364881 |
| 34 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.40073877 |
| 35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39908671 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39131826 |
| 37 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.38367475 |
| 38 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.37614518 |
| 39 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.36153777 |
| 40 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.35876816 |
| 41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.33776033 |
| 42 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.32977434 |
| 43 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.32571941 |
| 44 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.31705752 |
| 45 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.31325764 |
| 46 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.29038300 |
| 47 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.26921783 |
| 48 | ERA_21632823_ChIP-Seq_H3396_Human | 1.26077634 |
| 49 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.26075844 |
| 50 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.24868059 |
| 51 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.24868059 |
| 52 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.24546518 |
| 53 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.23579410 |
| 54 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.23192294 |
| 55 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.22566281 |
| 56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.19849477 |
| 57 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.18875599 |
| 58 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.18132744 |
| 59 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.17945387 |
| 60 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.17827516 |
| 61 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.17700370 |
| 62 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.16051289 |
| 63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.15873363 |
| 64 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.14021176 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.13645008 |
| 66 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.13387921 |
| 67 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.13037558 |
| 68 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.11199977 |
| 69 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.10083385 |
| 70 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.08862161 |
| 71 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.07948192 |
| 72 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.07886679 |
| 73 | SA1_27219007_Chip-Seq_Bcells_Human | 1.06507269 |
| 74 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.05793682 |
| 75 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.05646894 |
| 76 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04840219 |
| 77 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.03006917 |
| 78 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.99515517 |
| 79 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.99303584 |
| 80 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95226605 |
| 81 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94541435 |
| 82 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.94466599 |
| 83 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94326886 |
| 84 | P300_27268052_Chip-Seq_Bcells_Human | 0.94056027 |
| 85 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93544997 |
| 86 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.93300983 |
| 87 | P68_20966046_ChIP-Seq_HELA_Human | 0.93122564 |
| 88 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92921231 |
| 89 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.91852955 |
| 90 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.91719081 |
| 91 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.90630487 |
| 92 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90623375 |
| 93 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.90611442 |
| 94 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90412327 |
| 95 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.90222985 |
| 96 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.90183962 |
| 97 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.90183962 |
| 98 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.90175401 |
| 99 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.90050688 |
| 100 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.89549980 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.05077872 |
| 2 | MP0003123_paternal_imprinting | 3.25111007 |
| 3 | MP0002163_abnormal_gland_morphology | 3.08160048 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.00068899 |
| 5 | MP0002638_abnormal_pupillary_reflex | 2.91371893 |
| 6 | MP0004885_abnormal_endolymph | 2.53640442 |
| 7 | MP0003787_abnormal_imprinting | 2.42845753 |
| 8 | MP0005671_abnormal_response_to | 2.32183645 |
| 9 | MP0003646_muscle_fatigue | 2.31974064 |
| 10 | MP0005646_abnormal_pituitary_gland | 2.26494803 |
| 11 | MP0005645_abnormal_hypothalamus_physiol | 2.08906427 |
| 12 | MP0006276_abnormal_autonomic_nervous | 2.06125078 |
| 13 | MP0009046_muscle_twitch | 1.97985618 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 1.94509569 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 1.89127289 |
| 16 | MP0004742_abnormal_vestibular_system | 1.84662309 |
| 17 | MP0005377_hearing/vestibular/ear_phenot | 1.83534564 |
| 18 | MP0003878_abnormal_ear_physiology | 1.83534564 |
| 19 | MP0002102_abnormal_ear_morphology | 1.81302289 |
| 20 | MP0001919_abnormal_reproductive_system | 1.81263500 |
| 21 | MP0008789_abnormal_olfactory_epithelium | 1.77184397 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.76199991 |
| 23 | MP0001485_abnormal_pinna_reflex | 1.73156526 |
| 24 | MP0001440_abnormal_grooming_behavior | 1.69531680 |
| 25 | MP0002160_abnormal_reproductive_system | 1.68261655 |
| 26 | MP0008872_abnormal_physiological_respon | 1.68228668 |
| 27 | MP0004142_abnormal_muscle_tone | 1.67104077 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.60257964 |
| 29 | MP0002272_abnormal_nervous_system | 1.57059632 |
| 30 | MP0005379_endocrine/exocrine_gland_phen | 1.56235974 |
| 31 | MP0003011_delayed_dark_adaptation | 1.54918343 |
| 32 | MP0003880_abnormal_central_pattern | 1.54408335 |
| 33 | MP0004145_abnormal_muscle_electrophysio | 1.54142947 |
| 34 | MP0005389_reproductive_system_phenotype | 1.53204086 |
| 35 | MP0003121_genomic_imprinting | 1.53027614 |
| 36 | MP0003938_abnormal_ear_development | 1.52771007 |
| 37 | MP0000049_abnormal_middle_ear | 1.50760682 |
| 38 | MP0005083_abnormal_biliary_tract | 1.49614886 |
| 39 | MP0005499_abnormal_olfactory_system | 1.47345155 |
| 40 | MP0005394_taste/olfaction_phenotype | 1.47345155 |
| 41 | MP0004133_heterotaxia | 1.47246280 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.44835979 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.40684070 |
| 44 | MP0001348_abnormal_lacrimal_gland | 1.38133202 |
| 45 | MP0001905_abnormal_dopamine_level | 1.38021596 |
| 46 | MP0002876_abnormal_thyroid_physiology | 1.37952359 |
| 47 | MP0002735_abnormal_chemical_nociception | 1.34240174 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.31821364 |
| 49 | MP0000678_abnormal_parathyroid_gland | 1.31324022 |
| 50 | MP0001968_abnormal_touch/_nociception | 1.30237777 |
| 51 | MP0000631_abnormal_neuroendocrine_gland | 1.29896793 |
| 52 | MP0005423_abnormal_somatic_nervous | 1.28619572 |
| 53 | MP0002822_catalepsy | 1.27549811 |
| 54 | MP0001188_hyperpigmentation | 1.26408810 |
| 55 | MP0000026_abnormal_inner_ear | 1.26260447 |
| 56 | MP0009745_abnormal_behavioral_response | 1.26197397 |
| 57 | MP0002557_abnormal_social/conspecific_i | 1.25352367 |
| 58 | MP0003879_abnormal_hair_cell | 1.24662682 |
| 59 | MP0002095_abnormal_skin_pigmentation | 1.24533090 |
| 60 | MP0001970_abnormal_pain_threshold | 1.21037620 |
| 61 | MP0005253_abnormal_eye_physiology | 1.19037256 |
| 62 | MP0003315_abnormal_perineum_morphology | 1.16557211 |
| 63 | MP0002234_abnormal_pharynx_morphology | 1.14165277 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 1.12747335 |
| 65 | MP0002928_abnormal_bile_duct | 1.12518106 |
| 66 | MP0002736_abnormal_nociception_after | 1.12086786 |
| 67 | MP0005195_abnormal_posterior_eye | 1.06192773 |
| 68 | MP0003635_abnormal_synaptic_transmissio | 1.00272699 |
| 69 | MP0002837_dystrophic_cardiac_calcinosis | 0.99834252 |
| 70 | MP0002752_abnormal_somatic_nervous | 0.99037087 |
| 71 | MP0002572_abnormal_emotion/affect_behav | 0.97233297 |
| 72 | MP0001502_abnormal_circadian_rhythm | 0.95512949 |
| 73 | MP0000778_abnormal_nervous_system | 0.92654839 |
| 74 | MP0002067_abnormal_sensory_capabilities | 0.91926736 |
| 75 | MP0002063_abnormal_learning/memory/cond | 0.91623389 |
| 76 | MP0001486_abnormal_startle_reflex | 0.89651484 |
| 77 | MP0002184_abnormal_innervation | 0.89628122 |
| 78 | MP0001963_abnormal_hearing_physiology | 0.87142927 |
| 79 | MP0000955_abnormal_spinal_cord | 0.84705897 |
| 80 | MP0004147_increased_porphyrin_level | 0.82963113 |
| 81 | MP0001529_abnormal_vocalization | 0.82551330 |
| 82 | MP0004859_abnormal_synaptic_plasticity | 0.81688654 |
| 83 | MP0000230_abnormal_systemic_arterial | 0.81652586 |
| 84 | MP0002938_white_spotting | 0.81079041 |
| 85 | MP0004019_abnormal_vitamin_homeostasis | 0.78438262 |
| 86 | MP0001293_anophthalmia | 0.77846875 |
| 87 | MP0005670_abnormal_white_adipose | 0.77302023 |
| 88 | MP0004130_abnormal_muscle_cell | 0.76910788 |
| 89 | MP0009765_abnormal_xenobiotic_induced | 0.75580010 |
| 90 | MP0003638_abnormal_response/metabolism_ | 0.75299863 |
| 91 | MP0002064_seizures | 0.74778951 |
| 92 | MP0003936_abnormal_reproductive_system | 0.74113321 |
| 93 | MP0009333_abnormal_splenocyte_physiolog | 0.73593291 |
| 94 | MP0001986_abnormal_taste_sensitivity | 0.73012296 |
| 95 | MP0005174_abnormal_tail_pigmentation | 0.72780838 |
| 96 | MP0003119_abnormal_digestive_system | 0.72189762 |
| 97 | MP0002882_abnormal_neuron_morphology | 0.71146194 |
| 98 | MP0005410_abnormal_fertilization | 0.70753567 |
| 99 | MP0000685_abnormal_immune_system | 0.68729842 |
| 100 | MP0009764_decreased_sensitivity_to | 0.68329730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 4.69391479 |
| 2 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.92078614 |
| 3 | Reticulocytopenia (HP:0001896) | 3.79530493 |
| 4 | Abnormality of midbrain morphology (HP:0002418) | 3.76052834 |
| 5 | Molar tooth sign on MRI (HP:0002419) | 3.76052834 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.61470611 |
| 7 | Pancreatic cysts (HP:0001737) | 3.48604361 |
| 8 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.47917316 |
| 9 | Pancreatic fibrosis (HP:0100732) | 3.28389885 |
| 10 | Acute encephalopathy (HP:0006846) | 3.24265628 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.19709078 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.18582930 |
| 13 | True hermaphroditism (HP:0010459) | 3.12491068 |
| 14 | 11 pairs of ribs (HP:0000878) | 3.10399175 |
| 15 | Pendular nystagmus (HP:0012043) | 3.10078230 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.96244995 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 2.91035849 |
| 18 | Progressive macrocephaly (HP:0004481) | 2.83102754 |
| 19 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.77316564 |
| 20 | Decreased central vision (HP:0007663) | 2.76582050 |
| 21 | Asplenia (HP:0001746) | 2.73229893 |
| 22 | Radial bowing (HP:0002986) | 2.62095829 |
| 23 | Short femoral neck (HP:0100864) | 2.60208930 |
| 24 | Increased CSF lactate (HP:0002490) | 2.57643886 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.53099776 |
| 26 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.49129890 |
| 27 | Abolished electroretinogram (ERG) (HP:0000550) | 2.45116528 |
| 28 | Macrocytic anemia (HP:0001972) | 2.42504443 |
| 29 | Increased hepatocellular lipid droplets (HP:0006565) | 2.42120216 |
| 30 | Anencephaly (HP:0002323) | 2.41142690 |
| 31 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.39960985 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.39878678 |
| 33 | Hyperglycinemia (HP:0002154) | 2.39353588 |
| 34 | Absent thumb (HP:0009777) | 2.37628686 |
| 35 | Hypoplasia of the ulna (HP:0003022) | 2.33778970 |
| 36 | Nephronophthisis (HP:0000090) | 2.31818779 |
| 37 | Hypoplasia of the radius (HP:0002984) | 2.30351255 |
| 38 | Abnormality of the renal medulla (HP:0100957) | 2.29088915 |
| 39 | Polydipsia (HP:0001959) | 2.27555630 |
| 40 | Abnormal drinking behavior (HP:0030082) | 2.27555630 |
| 41 | Palpebral edema (HP:0100540) | 2.26064955 |
| 42 | Type II lissencephaly (HP:0007260) | 2.22924352 |
| 43 | Cystic liver disease (HP:0006706) | 2.22733694 |
| 44 | Severe visual impairment (HP:0001141) | 2.21795028 |
| 45 | Forearm undergrowth (HP:0009821) | 2.20343748 |
| 46 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 2.18701176 |
| 47 | Abnormal number of erythroid precursors (HP:0012131) | 2.18197377 |
| 48 | Myokymia (HP:0002411) | 2.17249310 |
| 49 | Pallor (HP:0000980) | 2.08002954 |
| 50 | Attenuation of retinal blood vessels (HP:0007843) | 2.07836565 |
| 51 | Renal Fanconi syndrome (HP:0001994) | 2.06611012 |
| 52 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.04066509 |
| 53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.04066509 |
| 54 | Polyuria (HP:0000103) | 2.03558040 |
| 55 | Sclerocornea (HP:0000647) | 2.03182408 |
| 56 | Abnormality of the renal cortex (HP:0011035) | 2.03131826 |
| 57 | Septo-optic dysplasia (HP:0100842) | 2.03131424 |
| 58 | Medial flaring of the eyebrow (HP:0010747) | 2.03008132 |
| 59 | Optic disc pallor (HP:0000543) | 2.01201663 |
| 60 | Supernumerary spleens (HP:0009799) | 1.99033197 |
| 61 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.98285056 |
| 62 | Increased muscle lipid content (HP:0009058) | 1.98239658 |
| 63 | IgG deficiency (HP:0004315) | 1.98178125 |
| 64 | Cerebral edema (HP:0002181) | 1.96797487 |
| 65 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.96259737 |
| 66 | Pachygyria (HP:0001302) | 1.92512472 |
| 67 | Chronic hepatic failure (HP:0100626) | 1.92490107 |
| 68 | Severe muscular hypotonia (HP:0006829) | 1.91734420 |
| 69 | Hepatocellular necrosis (HP:0001404) | 1.91568460 |
| 70 | Brushfield spots (HP:0001088) | 1.91352090 |
| 71 | Type 2 muscle fiber atrophy (HP:0003554) | 1.90011792 |
| 72 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.89570081 |
| 73 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.89570081 |
| 74 | Dyskinesia (HP:0100660) | 1.88947783 |
| 75 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 1.88889833 |
| 76 | Abnormality of the labia minora (HP:0012880) | 1.88074564 |
| 77 | Keratoconus (HP:0000563) | 1.87325914 |
| 78 | Increased corneal curvature (HP:0100692) | 1.87325914 |
| 79 | Increased intramyocellular lipid droplets (HP:0012240) | 1.87183859 |
| 80 | Hypoplasia of the uterus (HP:0000013) | 1.86714598 |
| 81 | Genetic anticipation (HP:0003743) | 1.84574622 |
| 82 | Enlarged kidneys (HP:0000105) | 1.83975440 |
| 83 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.79702532 |
| 84 | Colon cancer (HP:0003003) | 1.77948740 |
| 85 | Postaxial foot polydactyly (HP:0001830) | 1.77216651 |
| 86 | Abnormality of renal excretion (HP:0011036) | 1.76991899 |
| 87 | Agitation (HP:0000713) | 1.75258792 |
| 88 | Gait imbalance (HP:0002141) | 1.73478881 |
| 89 | Abnormality of renal resorption (HP:0011038) | 1.72666440 |
| 90 | Abnormal ciliary motility (HP:0012262) | 1.72040829 |
| 91 | Oligodactyly (hands) (HP:0001180) | 1.71367267 |
| 92 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.70935503 |
| 93 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.70804489 |
| 94 | Absent/shortened dynein arms (HP:0200106) | 1.70804489 |
| 95 | Maternal diabetes (HP:0009800) | 1.70209427 |
| 96 | Muscle fiber atrophy (HP:0100295) | 1.69963318 |
| 97 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.69449347 |
| 98 | Broad distal phalanx of finger (HP:0009836) | 1.69262544 |
| 99 | Stenosis of the external auditory canal (HP:0000402) | 1.68226647 |
| 100 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.67901539 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 5.31162539 |
| 2 | TLK1 | 3.85543599 |
| 3 | STK39 | 3.68850520 |
| 4 | ZAK | 3.10792212 |
| 5 | ADRBK2 | 2.98110774 |
| 6 | CDC7 | 2.87622721 |
| 7 | TXK | 2.43268398 |
| 8 | WNK1 | 2.37794495 |
| 9 | GRK1 | 2.32402698 |
| 10 | BCKDK | 2.25119451 |
| 11 | BMPR1B | 1.99598021 |
| 12 | TIE1 | 1.79350434 |
| 13 | DYRK2 | 1.79007219 |
| 14 | CDK19 | 1.70078968 |
| 15 | VRK1 | 1.64859980 |
| 16 | KDR | 1.60499418 |
| 17 | PINK1 | 1.49321540 |
| 18 | AURKA | 1.40473627 |
| 19 | MAP4K1 | 1.30569601 |
| 20 | RPS6KA5 | 1.28728273 |
| 21 | CAMKK2 | 1.28380953 |
| 22 | MAP2K7 | 1.28034005 |
| 23 | CAMKK1 | 1.27287456 |
| 24 | STK16 | 1.24975895 |
| 25 | LIMK1 | 1.24758191 |
| 26 | PRKCQ | 1.23801141 |
| 27 | PIK3CA | 1.21579554 |
| 28 | NTRK2 | 1.17857321 |
| 29 | MAP4K2 | 1.16705237 |
| 30 | TESK2 | 1.14176281 |
| 31 | FRK | 1.11634751 |
| 32 | INSRR | 1.10450909 |
| 33 | MAP3K4 | 1.08002975 |
| 34 | CSNK1G3 | 1.01498631 |
| 35 | EPHB2 | 1.01233290 |
| 36 | BRSK1 | 0.98131140 |
| 37 | MAP3K11 | 0.95232076 |
| 38 | MARK3 | 0.95047381 |
| 39 | PKN1 | 0.93358740 |
| 40 | TAOK3 | 0.90238352 |
| 41 | TYRO3 | 0.86780916 |
| 42 | NUAK1 | 0.86287961 |
| 43 | CSNK1G2 | 0.85247427 |
| 44 | TAF1 | 0.82295931 |
| 45 | ITK | 0.81350926 |
| 46 | NTRK3 | 0.80600836 |
| 47 | PIM2 | 0.79228400 |
| 48 | CSNK1G1 | 0.78556253 |
| 49 | CSNK1A1L | 0.76781686 |
| 50 | DAPK3 | 0.76378073 |
| 51 | VRK2 | 0.75810074 |
| 52 | CAMK1 | 0.74785118 |
| 53 | SYK | 0.73000813 |
| 54 | IKBKB | 0.71533259 |
| 55 | OBSCN | 0.71322653 |
| 56 | OXSR1 | 0.70349235 |
| 57 | ADRBK1 | 0.69996044 |
| 58 | TEC | 0.69948047 |
| 59 | SIK2 | 0.68962422 |
| 60 | PRKCG | 0.68196706 |
| 61 | WNK3 | 0.67313762 |
| 62 | NEK2 | 0.65236236 |
| 63 | PRKACA | 0.64859167 |
| 64 | MAPK13 | 0.64487272 |
| 65 | CASK | 0.61100359 |
| 66 | ABL2 | 0.60786622 |
| 67 | PIM1 | 0.58800718 |
| 68 | PHKG2 | 0.56530797 |
| 69 | PHKG1 | 0.56530797 |
| 70 | NME2 | 0.55926687 |
| 71 | TRIM28 | 0.55917248 |
| 72 | AURKB | 0.54498842 |
| 73 | CSNK2A2 | 0.53246615 |
| 74 | MAPK15 | 0.51377718 |
| 75 | MARK1 | 0.50961023 |
| 76 | IKBKE | 0.50876314 |
| 77 | TGFBR1 | 0.49035160 |
| 78 | SGK494 | 0.48809638 |
| 79 | SGK223 | 0.48809638 |
| 80 | CAMK2A | 0.48642478 |
| 81 | MAP2K2 | 0.48639141 |
| 82 | CSNK1A1 | 0.48472778 |
| 83 | CSNK1E | 0.46954610 |
| 84 | ATR | 0.46704613 |
| 85 | NME1 | 0.45711319 |
| 86 | CSNK2A1 | 0.44638498 |
| 87 | PAK3 | 0.44356558 |
| 88 | BTK | 0.44133914 |
| 89 | DYRK1B | 0.43810071 |
| 90 | LYN | 0.40388278 |
| 91 | STK11 | 0.38598885 |
| 92 | IRAK4 | 0.38049494 |
| 93 | DAPK2 | 0.38023195 |
| 94 | PRKCA | 0.36979999 |
| 95 | PRKCI | 0.36335126 |
| 96 | GRK7 | 0.35548716 |
| 97 | CHEK2 | 0.34667951 |
| 98 | FES | 0.33360893 |
| 99 | PLK1 | 0.32445467 |
| 100 | PRKCH | 0.31523147 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.67533430 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.73093139 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.05359482 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.88731977 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.65517963 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.64284154 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.52041837 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.46557146 |
| 9 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.40086818 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.28523426 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.25673159 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.17566362 |
| 13 | Asthma_Homo sapiens_hsa05310 | 2.11725032 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04265820 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.98920856 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.90227198 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.82513974 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.70866898 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.68560912 |
| 20 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.67591591 |
| 21 | Alcoholism_Homo sapiens_hsa05034 | 1.47324233 |
| 22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.47143556 |
| 23 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.46762339 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.44375462 |
| 25 | Proteasome_Homo sapiens_hsa03050 | 1.37057439 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.35483186 |
| 27 | Olfactory transduction_Homo sapiens_hsa04740 | 1.34623479 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.29634053 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.26061744 |
| 30 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.19674473 |
| 31 | Homologous recombination_Homo sapiens_hsa03440 | 1.18403975 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.18076111 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.17027852 |
| 34 | Protein export_Homo sapiens_hsa03060 | 1.16973049 |
| 35 | Morphine addiction_Homo sapiens_hsa05032 | 1.12545729 |
| 36 | Sulfur relay system_Homo sapiens_hsa04122 | 1.11964210 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.11204138 |
| 38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.08089432 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.99236215 |
| 40 | RNA polymerase_Homo sapiens_hsa03020 | 0.97802772 |
| 41 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.96822332 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 0.96156046 |
| 43 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.93988410 |
| 44 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.90554462 |
| 45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.89191197 |
| 46 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.86225713 |
| 47 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.86061958 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.84449419 |
| 49 | RNA degradation_Homo sapiens_hsa03018 | 0.83449487 |
| 50 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.82354355 |
| 51 | GABAergic synapse_Homo sapiens_hsa04727 | 0.81907092 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80840984 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.78968595 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.76602806 |
| 55 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.76551130 |
| 56 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.75276245 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72940271 |
| 58 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.69730650 |
| 59 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.68843919 |
| 60 | Insulin secretion_Homo sapiens_hsa04911 | 0.68595074 |
| 61 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65456393 |
| 62 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65369611 |
| 63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.63887327 |
| 64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61448871 |
| 65 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59717193 |
| 66 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.59532034 |
| 67 | Taste transduction_Homo sapiens_hsa04742 | 0.59060246 |
| 68 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.56103213 |
| 69 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.54273047 |
| 70 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.54065970 |
| 71 | Purine metabolism_Homo sapiens_hsa00230 | 0.50913712 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50430931 |
| 73 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50224542 |
| 74 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.50213402 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50063396 |
| 76 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.48568875 |
| 77 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.48188738 |
| 78 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.47458612 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44303779 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43964174 |
| 81 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.42929720 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42758167 |
| 83 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.42039503 |
| 84 | DNA replication_Homo sapiens_hsa03030 | 0.41605656 |
| 85 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.39884765 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38855997 |
| 87 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.38323464 |
| 88 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.37000964 |
| 89 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.36848034 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34464025 |
| 91 | Basal transcription factors_Homo sapiens_hsa03022 | 0.32379813 |
| 92 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.30885527 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30430775 |
| 94 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.30074751 |
| 95 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.29294842 |
| 96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.28915221 |
| 97 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.28492339 |
| 98 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.28183343 |
| 99 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.28142621 |
| 100 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.25912222 |

