

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.45317856 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.45317856 |
| 3 | DNA deamination (GO:0045006) | 5.05924620 |
| 4 | behavioral response to nicotine (GO:0035095) | 4.98726437 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.62359752 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 4.61609544 |
| 7 | protein neddylation (GO:0045116) | 4.26310599 |
| 8 | negative regulation of mast cell activation (GO:0033004) | 4.15375302 |
| 9 | viral transcription (GO:0019083) | 3.99319183 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 3.97623169 |
| 11 | translational termination (GO:0006415) | 3.92639084 |
| 12 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.91283505 |
| 13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.81385983 |
| 14 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.64959132 |
| 15 | GTP biosynthetic process (GO:0006183) | 3.63914203 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.63406681 |
| 17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.54866130 |
| 18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.54866130 |
| 19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.54866130 |
| 20 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53563427 |
| 21 | electron transport chain (GO:0022900) | 3.51192074 |
| 22 | ribosomal small subunit biogenesis (GO:0042274) | 3.51169121 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.50779168 |
| 24 | respiratory electron transport chain (GO:0022904) | 3.49622308 |
| 25 | maturation of SSU-rRNA (GO:0030490) | 3.49432556 |
| 26 | translational elongation (GO:0006414) | 3.45379623 |
| 27 | termination of RNA polymerase III transcription (GO:0006386) | 3.45072683 |
| 28 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.45072683 |
| 29 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.44646207 |
| 30 | protein targeting to ER (GO:0045047) | 3.42147048 |
| 31 | cotranslational protein targeting to membrane (GO:0006613) | 3.42065985 |
| 32 | protein complex biogenesis (GO:0070271) | 3.41768987 |
| 33 | regulation of chronic inflammatory response (GO:0002676) | 3.36466253 |
| 34 | pseudouridine synthesis (GO:0001522) | 3.35532125 |
| 35 | cytidine deamination (GO:0009972) | 3.30258742 |
| 36 | cytidine metabolic process (GO:0046087) | 3.30258742 |
| 37 | cytidine catabolic process (GO:0006216) | 3.30258742 |
| 38 | ribosomal large subunit biogenesis (GO:0042273) | 3.26078591 |
| 39 | protein localization to endoplasmic reticulum (GO:0070972) | 3.24793077 |
| 40 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.24344485 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.17011140 |
| 42 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.14227198 |
| 43 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.14227198 |
| 44 | negative regulation of telomere maintenance (GO:0032205) | 3.13539233 |
| 45 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.12995689 |
| 46 | rRNA modification (GO:0000154) | 3.12140270 |
| 47 | translation (GO:0006412) | 3.12026943 |
| 48 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.11129057 |
| 49 | peptidyl-histidine modification (GO:0018202) | 3.05972731 |
| 50 | positive regulation of prostaglandin secretion (GO:0032308) | 3.02094155 |
| 51 | positive regulation of fatty acid transport (GO:2000193) | 3.00124123 |
| 52 | cellular component biogenesis (GO:0044085) | 2.98883638 |
| 53 | viral life cycle (GO:0019058) | 2.98419084 |
| 54 | rRNA processing (GO:0006364) | 2.97489982 |
| 55 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.97068683 |
| 56 | ATP biosynthetic process (GO:0006754) | 2.96916159 |
| 57 | UTP biosynthetic process (GO:0006228) | 2.96074321 |
| 58 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.93674671 |
| 59 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.93548018 |
| 60 | rRNA metabolic process (GO:0016072) | 2.92771729 |
| 61 | base-excision repair, AP site formation (GO:0006285) | 2.92482102 |
| 62 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.92010463 |
| 63 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.91534350 |
| 64 | kynurenine metabolic process (GO:0070189) | 2.88804964 |
| 65 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.88544727 |
| 66 | cellular protein complex disassembly (GO:0043624) | 2.87075950 |
| 67 | maturation of 5.8S rRNA (GO:0000460) | 2.86290741 |
| 68 | replication fork processing (GO:0031297) | 2.85922848 |
| 69 | positive regulation of defense response to virus by host (GO:0002230) | 2.84346510 |
| 70 | protein-cofactor linkage (GO:0018065) | 2.83678457 |
| 71 | protein polyglutamylation (GO:0018095) | 2.83651402 |
| 72 | tRNA processing (GO:0008033) | 2.80194189 |
| 73 | UTP metabolic process (GO:0046051) | 2.79847498 |
| 74 | translational initiation (GO:0006413) | 2.79528674 |
| 75 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.79238217 |
| 76 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.76502233 |
| 77 | cell proliferation in forebrain (GO:0021846) | 2.73752266 |
| 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.72288004 |
| 79 | proteasome assembly (GO:0043248) | 2.71971236 |
| 80 | response to pheromone (GO:0019236) | 2.71924164 |
| 81 | hydrogen ion transmembrane transport (GO:1902600) | 2.71336015 |
| 82 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.70361757 |
| 83 | positive regulation of T cell apoptotic process (GO:0070234) | 2.69424207 |
| 84 | endoderm formation (GO:0001706) | 2.69210017 |
| 85 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.69126053 |
| 86 | fucose catabolic process (GO:0019317) | 2.67747511 |
| 87 | L-fucose metabolic process (GO:0042354) | 2.67747511 |
| 88 | L-fucose catabolic process (GO:0042355) | 2.67747511 |
| 89 | piRNA metabolic process (GO:0034587) | 2.67269131 |
| 90 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.67231471 |
| 91 | ribosome biogenesis (GO:0042254) | 2.65940871 |
| 92 | positive regulation of icosanoid secretion (GO:0032305) | 2.64518559 |
| 93 | regulation of immunoglobulin secretion (GO:0051023) | 2.64039068 |
| 94 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.63558743 |
| 95 | proton transport (GO:0015992) | 2.57338523 |
| 96 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.56646667 |
| 97 | regulation of activation of Janus kinase activity (GO:0010533) | 2.54746079 |
| 98 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.50152515 |
| 99 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.49643222 |
| 100 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.49525696 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.19209663 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.83975876 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.76680054 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.34409648 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.30920252 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.24660697 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.11657428 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.09192610 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.76215825 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.76075042 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.73057155 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.66365019 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.62687550 |
| 14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.59019338 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.54812368 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.18582451 |
| 17 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.93000642 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.92892508 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90276076 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.85412210 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.81666943 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.81294906 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.77259136 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72708635 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66148899 |
| 26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62856776 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59833302 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.56371317 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50529820 |
| 30 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.49355883 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.45910015 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.44578378 |
| 33 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.40849072 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40780352 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.40373385 |
| 36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.34971264 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.32782990 |
| 38 | NCOR_22424771_ChIP-Seq_293T_Human | 1.32601207 |
| 39 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31706732 |
| 40 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.31065458 |
| 41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30870846 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.28256863 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28062603 |
| 44 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.27163095 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.26506150 |
| 46 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.25488347 |
| 47 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23122339 |
| 48 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.21528312 |
| 49 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.21169284 |
| 50 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.19770081 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.18011674 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.18011674 |
| 53 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.18005219 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.15757864 |
| 55 | ERA_21632823_ChIP-Seq_H3396_Human | 1.14981269 |
| 56 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.11928463 |
| 57 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.11554885 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.09942077 |
| 59 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08933016 |
| 60 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.07182828 |
| 61 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.06397589 |
| 62 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06153724 |
| 63 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05710444 |
| 64 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.05468164 |
| 65 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.04272000 |
| 66 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.02620178 |
| 67 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.02471614 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.01986419 |
| 69 | P300_19829295_ChIP-Seq_ESCs_Human | 1.01602849 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.01470622 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.00464725 |
| 72 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.99435849 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 0.97645229 |
| 74 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.97562036 |
| 75 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97207464 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.96918581 |
| 77 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.96311236 |
| 78 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.96307030 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96187185 |
| 80 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.95700577 |
| 81 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95373021 |
| 82 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.94959761 |
| 83 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.94596232 |
| 84 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.92565410 |
| 85 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91850383 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.91742759 |
| 87 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90359573 |
| 88 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89346460 |
| 89 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.88953689 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.88953689 |
| 91 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.88148066 |
| 92 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87545964 |
| 93 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.86639580 |
| 94 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.86458811 |
| 95 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.86286216 |
| 96 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.85950680 |
| 97 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.85591794 |
| 98 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.85343126 |
| 99 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.84893813 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.84893813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.62476031 |
| 2 | MP0008877_abnormal_DNA_methylation | 2.88954755 |
| 3 | MP0003646_muscle_fatigue | 2.63055810 |
| 4 | MP0009379_abnormal_foot_pigmentation | 2.57336208 |
| 5 | MP0003787_abnormal_imprinting | 2.42804974 |
| 6 | MP0005671_abnormal_response_to | 2.39158592 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.18895195 |
| 8 | MP0002102_abnormal_ear_morphology | 2.17531187 |
| 9 | MP0005646_abnormal_pituitary_gland | 2.14047602 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.09879941 |
| 11 | MP0008872_abnormal_physiological_respon | 2.05806483 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.00395461 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 1.97252659 |
| 14 | MP0004885_abnormal_endolymph | 1.91167806 |
| 15 | MP0001835_abnormal_antigen_presentation | 1.90900405 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 1.87700485 |
| 17 | MP0008789_abnormal_olfactory_epithelium | 1.86344848 |
| 18 | MP0004147_increased_porphyrin_level | 1.84157971 |
| 19 | MP0000685_abnormal_immune_system | 1.80700634 |
| 20 | MP0002736_abnormal_nociception_after | 1.78154364 |
| 21 | MP0002876_abnormal_thyroid_physiology | 1.76078294 |
| 22 | MP0005551_abnormal_eye_electrophysiolog | 1.67097857 |
| 23 | MP0001293_anophthalmia | 1.59213036 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.58981543 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.51202899 |
| 26 | MP0005389_reproductive_system_phenotype | 1.51175756 |
| 27 | MP0001919_abnormal_reproductive_system | 1.49239147 |
| 28 | MP0001873_stomach_inflammation | 1.43035637 |
| 29 | MP0005253_abnormal_eye_physiology | 1.42680749 |
| 30 | MP0001485_abnormal_pinna_reflex | 1.42512578 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.39148089 |
| 32 | MP0003195_calcinosis | 1.38264260 |
| 33 | MP0001348_abnormal_lacrimal_gland | 1.38095240 |
| 34 | MP0004742_abnormal_vestibular_system | 1.37809773 |
| 35 | MP0002272_abnormal_nervous_system | 1.35992876 |
| 36 | MP0002160_abnormal_reproductive_system | 1.35863394 |
| 37 | MP0003786_premature_aging | 1.34342291 |
| 38 | MP0004142_abnormal_muscle_tone | 1.33167035 |
| 39 | MP0002653_abnormal_ependyma_morphology | 1.32182465 |
| 40 | MP0001905_abnormal_dopamine_level | 1.30270040 |
| 41 | MP0000372_irregular_coat_pigmentation | 1.28069249 |
| 42 | MP0003011_delayed_dark_adaptation | 1.27149425 |
| 43 | MP0001986_abnormal_taste_sensitivity | 1.25574828 |
| 44 | MP0000631_abnormal_neuroendocrine_gland | 1.23044895 |
| 45 | MP0005394_taste/olfaction_phenotype | 1.22184167 |
| 46 | MP0005499_abnormal_olfactory_system | 1.22184167 |
| 47 | MP0003693_abnormal_embryo_hatching | 1.21148295 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.20897574 |
| 49 | MP0000049_abnormal_middle_ear | 1.20814953 |
| 50 | MP0009745_abnormal_behavioral_response | 1.20481910 |
| 51 | MP0005377_hearing/vestibular/ear_phenot | 1.20090310 |
| 52 | MP0003878_abnormal_ear_physiology | 1.20090310 |
| 53 | MP0003123_paternal_imprinting | 1.20028802 |
| 54 | MP0003121_genomic_imprinting | 1.19535916 |
| 55 | MP0003718_maternal_effect | 1.16469790 |
| 56 | MP0002163_abnormal_gland_morphology | 1.14742321 |
| 57 | MP0008058_abnormal_DNA_repair | 1.09984838 |
| 58 | MP0001800_abnormal_humoral_immune | 1.09944877 |
| 59 | MP0002938_white_spotting | 1.09400470 |
| 60 | MP0003880_abnormal_central_pattern | 1.08379630 |
| 61 | MP0002095_abnormal_skin_pigmentation | 1.07638782 |
| 62 | MP0001970_abnormal_pain_threshold | 1.03071476 |
| 63 | MP0002148_abnormal_hypersensitivity_rea | 1.02734683 |
| 64 | MP0000569_abnormal_digit_pigmentation | 1.01196818 |
| 65 | MP0005387_immune_system_phenotype | 0.99961973 |
| 66 | MP0001790_abnormal_immune_system | 0.99961973 |
| 67 | MP0005195_abnormal_posterior_eye | 0.97437097 |
| 68 | MP0002210_abnormal_sex_determination | 0.97199450 |
| 69 | MP0002557_abnormal_social/conspecific_i | 0.94133988 |
| 70 | MP0010094_abnormal_chromosome_stability | 0.93734426 |
| 71 | MP0002638_abnormal_pupillary_reflex | 0.92951747 |
| 72 | MP0002277_abnormal_respiratory_mucosa | 0.92371355 |
| 73 | MP0004133_heterotaxia | 0.91795214 |
| 74 | MP0002837_dystrophic_cardiac_calcinosis | 0.91546481 |
| 75 | MP0003186_abnormal_redox_activity | 0.88689618 |
| 76 | MP0002752_abnormal_somatic_nervous | 0.85614435 |
| 77 | MP0009764_decreased_sensitivity_to | 0.83781510 |
| 78 | MP0000778_abnormal_nervous_system | 0.82921795 |
| 79 | MP0006036_abnormal_mitochondrial_physio | 0.82865371 |
| 80 | MP0001440_abnormal_grooming_behavior | 0.82226345 |
| 81 | MP0002184_abnormal_innervation | 0.81121923 |
| 82 | MP0001501_abnormal_sleep_pattern | 0.81034346 |
| 83 | MP0002572_abnormal_emotion/affect_behav | 0.80811148 |
| 84 | MP0004043_abnormal_pH_regulation | 0.80696303 |
| 85 | MP0010030_abnormal_orbit_morphology | 0.80644909 |
| 86 | MP0008995_early_reproductive_senescence | 0.80343294 |
| 87 | MP0001502_abnormal_circadian_rhythm | 0.80182070 |
| 88 | MP0002067_abnormal_sensory_capabilities | 0.79435959 |
| 89 | MP0003122_maternal_imprinting | 0.79398437 |
| 90 | MP0002063_abnormal_learning/memory/cond | 0.78992490 |
| 91 | MP0003936_abnormal_reproductive_system | 0.78020653 |
| 92 | MP0008775_abnormal_heart_ventricle | 0.77638945 |
| 93 | MP0005083_abnormal_biliary_tract | 0.77533485 |
| 94 | MP0005075_abnormal_melanosome_morpholog | 0.76356158 |
| 95 | MP0002254_reproductive_system_inflammat | 0.76312892 |
| 96 | MP0003866_abnormal_defecation | 0.76193796 |
| 97 | MP0001486_abnormal_startle_reflex | 0.75545496 |
| 98 | MP0003938_abnormal_ear_development | 0.75319156 |
| 99 | MP0002723_abnormal_immune_serum | 0.74981212 |
| 100 | MP0001119_abnormal_female_reproductive | 0.73925863 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 4.17625792 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.81450118 |
| 3 | Pancreatic cysts (HP:0001737) | 3.67034990 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.48633448 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 3.43612315 |
| 6 | Molar tooth sign on MRI (HP:0002419) | 3.43612315 |
| 7 | Acute encephalopathy (HP:0006846) | 3.41198426 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.37485428 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.35268929 |
| 10 | Increased CSF lactate (HP:0002490) | 3.34295021 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.31965640 |
| 12 | Asplenia (HP:0001746) | 3.18188144 |
| 13 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.14899934 |
| 14 | Nephronophthisis (HP:0000090) | 3.07913076 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.05333828 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97792539 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 2.97422772 |
| 18 | Reticulocytopenia (HP:0001896) | 2.96646413 |
| 19 | Pendular nystagmus (HP:0012043) | 2.91877696 |
| 20 | Lipid accumulation in hepatocytes (HP:0006561) | 2.82409842 |
| 21 | True hermaphroditism (HP:0010459) | 2.77891406 |
| 22 | Decreased central vision (HP:0007663) | 2.75709021 |
| 23 | Abnormality of the renal medulla (HP:0100957) | 2.74502101 |
| 24 | IgG deficiency (HP:0004315) | 2.73513288 |
| 25 | Colon cancer (HP:0003003) | 2.67464083 |
| 26 | Methylmalonic acidemia (HP:0002912) | 2.65004222 |
| 27 | Optic disc pallor (HP:0000543) | 2.61055591 |
| 28 | Prostate neoplasm (HP:0100787) | 2.58567941 |
| 29 | Abnormal drinking behavior (HP:0030082) | 2.56340078 |
| 30 | Polydipsia (HP:0001959) | 2.56340078 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.55158818 |
| 32 | Hepatocellular necrosis (HP:0001404) | 2.52882264 |
| 33 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.52672768 |
| 34 | Increased serum lactate (HP:0002151) | 2.51392219 |
| 35 | Stomatitis (HP:0010280) | 2.48517551 |
| 36 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.46306049 |
| 37 | Testicular atrophy (HP:0000029) | 2.46088230 |
| 38 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.45116849 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.39524446 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.39352445 |
| 41 | Congenital, generalized hypertrichosis (HP:0004540) | 2.37386132 |
| 42 | Supernumerary spleens (HP:0009799) | 2.37320729 |
| 43 | Type II lissencephaly (HP:0007260) | 2.32377816 |
| 44 | Absent thumb (HP:0009777) | 2.31900550 |
| 45 | Bile duct proliferation (HP:0001408) | 2.30593918 |
| 46 | Abnormal biliary tract physiology (HP:0012439) | 2.30593918 |
| 47 | Cerebral edema (HP:0002181) | 2.26778353 |
| 48 | Septo-optic dysplasia (HP:0100842) | 2.26745500 |
| 49 | Abolished electroretinogram (ERG) (HP:0000550) | 2.25789278 |
| 50 | Methylmalonic aciduria (HP:0012120) | 2.21769343 |
| 51 | Abnormal number of erythroid precursors (HP:0012131) | 2.21676354 |
| 52 | Chronic hepatic failure (HP:0100626) | 2.21518504 |
| 53 | Hepatic necrosis (HP:0002605) | 2.20817079 |
| 54 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.20482429 |
| 55 | Abnormality of the labia minora (HP:0012880) | 2.19856365 |
| 56 | Macrocytic anemia (HP:0001972) | 2.16750396 |
| 57 | Hyperglycinemia (HP:0002154) | 2.15257748 |
| 58 | Tubular atrophy (HP:0000092) | 2.14942596 |
| 59 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.11270458 |
| 60 | Polyuria (HP:0000103) | 2.09149338 |
| 61 | Sclerocornea (HP:0000647) | 2.04264836 |
| 62 | Renal cortical cysts (HP:0000803) | 2.01962731 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.01646947 |
| 64 | Dyschromatopsia (HP:0007641) | 2.00955725 |
| 65 | Cystic liver disease (HP:0006706) | 1.99874928 |
| 66 | Oligodactyly (hands) (HP:0001180) | 1.98237344 |
| 67 | Exertional dyspnea (HP:0002875) | 1.96604771 |
| 68 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.94893170 |
| 69 | Abnormality of alanine metabolism (HP:0010916) | 1.94893170 |
| 70 | Hyperalaninemia (HP:0003348) | 1.94893170 |
| 71 | Pancytopenia (HP:0001876) | 1.94378347 |
| 72 | Attenuation of retinal blood vessels (HP:0007843) | 1.93964835 |
| 73 | Increased muscle lipid content (HP:0009058) | 1.92802543 |
| 74 | Congenital hepatic fibrosis (HP:0002612) | 1.91917849 |
| 75 | Lactic acidosis (HP:0003128) | 1.90842653 |
| 76 | Adrenal hypoplasia (HP:0000835) | 1.89467000 |
| 77 | Severe visual impairment (HP:0001141) | 1.89367912 |
| 78 | Increased IgM level (HP:0003496) | 1.86769530 |
| 79 | Lethargy (HP:0001254) | 1.82080062 |
| 80 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.81504534 |
| 81 | Anencephaly (HP:0002323) | 1.80952453 |
| 82 | Optic nerve hypoplasia (HP:0000609) | 1.79921146 |
| 83 | Abnormality of the ileum (HP:0001549) | 1.74971067 |
| 84 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.74744130 |
| 85 | Absent/shortened dynein arms (HP:0200106) | 1.74744130 |
| 86 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.73820297 |
| 87 | Exercise intolerance (HP:0003546) | 1.73415887 |
| 88 | Hypoplasia of the ulna (HP:0003022) | 1.71917611 |
| 89 | Meckel diverticulum (HP:0002245) | 1.71308888 |
| 90 | Male pseudohermaphroditism (HP:0000037) | 1.67945734 |
| 91 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.66389475 |
| 92 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.66389475 |
| 93 | Leukodystrophy (HP:0002415) | 1.66197958 |
| 94 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.65233895 |
| 95 | Medial flaring of the eyebrow (HP:0010747) | 1.64580431 |
| 96 | Abnormal urine output (HP:0012590) | 1.64493912 |
| 97 | Respiratory difficulties (HP:0002880) | 1.64071654 |
| 98 | Pallor (HP:0000980) | 1.63380399 |
| 99 | Abnormality of the prostate (HP:0008775) | 1.62830985 |
| 100 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.62701083 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 3.56349474 |
| 2 | TXK | 3.00547575 |
| 3 | GRK1 | 2.95199643 |
| 4 | VRK2 | 2.84694228 |
| 5 | ADRBK2 | 2.69586284 |
| 6 | ZAK | 2.67661373 |
| 7 | NUAK1 | 2.66260384 |
| 8 | TAOK3 | 2.58248271 |
| 9 | TIE1 | 2.14608848 |
| 10 | LIMK1 | 1.99667173 |
| 11 | TESK2 | 1.87935373 |
| 12 | MST4 | 1.81585375 |
| 13 | BCKDK | 1.71543983 |
| 14 | SRPK1 | 1.66722090 |
| 15 | CDC7 | 1.64697663 |
| 16 | TSSK6 | 1.64251829 |
| 17 | DYRK2 | 1.62601419 |
| 18 | WNK3 | 1.55908341 |
| 19 | FRK | 1.52563269 |
| 20 | TLK1 | 1.51831309 |
| 21 | MAP4K1 | 1.49299170 |
| 22 | STK16 | 1.48674625 |
| 23 | STK39 | 1.40439245 |
| 24 | CAMKK2 | 1.38348815 |
| 25 | VRK1 | 1.37035062 |
| 26 | MAP4K2 | 1.32118228 |
| 27 | MAP3K11 | 1.25659892 |
| 28 | NME1 | 1.24533989 |
| 29 | NME2 | 1.23963772 |
| 30 | FES | 1.21598605 |
| 31 | BMPR1B | 1.20554298 |
| 32 | NEK1 | 1.18794937 |
| 33 | BUB1 | 1.18074706 |
| 34 | OXSR1 | 1.17378911 |
| 35 | TAF1 | 1.09942366 |
| 36 | GRK5 | 1.06397599 |
| 37 | PINK1 | 1.01086002 |
| 38 | KDR | 1.00714689 |
| 39 | PLK3 | 0.99286989 |
| 40 | PHKG2 | 0.98503662 |
| 41 | PHKG1 | 0.98503662 |
| 42 | IKBKB | 0.96864484 |
| 43 | TNIK | 0.93068307 |
| 44 | MAPK13 | 0.90944087 |
| 45 | PLK2 | 0.87025257 |
| 46 | EIF2AK3 | 0.83797767 |
| 47 | PIK3CA | 0.83584637 |
| 48 | PLK4 | 0.82651508 |
| 49 | INSRR | 0.82355361 |
| 50 | CDK8 | 0.80651619 |
| 51 | TEC | 0.77974214 |
| 52 | CSNK1G3 | 0.77317446 |
| 53 | AURKA | 0.76427251 |
| 54 | CSNK1G2 | 0.76383482 |
| 55 | ATR | 0.75028083 |
| 56 | MAP2K2 | 0.74956755 |
| 57 | CAMKK1 | 0.74169308 |
| 58 | ADRBK1 | 0.73941701 |
| 59 | PRKCQ | 0.73316601 |
| 60 | EIF2AK2 | 0.71932699 |
| 61 | PDK2 | 0.71056897 |
| 62 | PRKCG | 0.69643118 |
| 63 | PLK1 | 0.69175027 |
| 64 | BRSK1 | 0.68480781 |
| 65 | ITK | 0.67977557 |
| 66 | CSNK1A1L | 0.67613116 |
| 67 | EIF2AK1 | 0.66222880 |
| 68 | EPHB2 | 0.65950018 |
| 69 | AURKB | 0.65487173 |
| 70 | RPS6KA5 | 0.65485851 |
| 71 | CSNK2A2 | 0.64661412 |
| 72 | TRIM28 | 0.63991205 |
| 73 | CSNK1G1 | 0.63694105 |
| 74 | MAPKAPK3 | 0.62167500 |
| 75 | NTRK2 | 0.58043400 |
| 76 | MAPKAPK5 | 0.57535016 |
| 77 | SYK | 0.57018614 |
| 78 | DAPK1 | 0.55692321 |
| 79 | WNK1 | 0.54807108 |
| 80 | PRKCI | 0.52866862 |
| 81 | CSNK2A1 | 0.52423826 |
| 82 | ABL2 | 0.50889035 |
| 83 | PRKACA | 0.50531861 |
| 84 | PBK | 0.49249068 |
| 85 | NEK2 | 0.49176124 |
| 86 | PAK3 | 0.47050948 |
| 87 | BTK | 0.46858410 |
| 88 | TYRO3 | 0.44916895 |
| 89 | OBSCN | 0.44553651 |
| 90 | CSNK1E | 0.44262041 |
| 91 | KIT | 0.42857863 |
| 92 | CSNK1A1 | 0.42627174 |
| 93 | DAPK2 | 0.40438600 |
| 94 | CAMK1 | 0.39397292 |
| 95 | CASK | 0.37919440 |
| 96 | CDK19 | 0.36931562 |
| 97 | CHEK2 | 0.35929449 |
| 98 | PRKCE | 0.35615381 |
| 99 | LCK | 0.35142994 |
| 100 | MAP2K7 | 0.34516806 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.99130363 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.67983106 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.54307040 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.15062033 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.68360421 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.49272194 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.43084266 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.23455810 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.18366356 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.09932211 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.04486231 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.02131284 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.99541539 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.99470428 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.97118286 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.96044015 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.93507172 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.86814246 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.78900241 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.78743246 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.78070249 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.77150577 |
| 23 | Mismatch repair_Homo sapiens_hsa03430 | 1.73874331 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.68383476 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.66811123 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.66081793 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.63964727 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56696137 |
| 29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.51033660 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.48145795 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.48002271 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.37921505 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.37107845 |
| 34 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.31316259 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 1.30217605 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.22607600 |
| 37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.19325730 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.18280308 |
| 39 | RNA transport_Homo sapiens_hsa03013 | 1.18066862 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13204041 |
| 41 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.08988261 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.06241153 |
| 43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03897463 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 0.99681474 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98165344 |
| 46 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97398345 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.91444367 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.84285885 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.83247566 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.82567475 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80124464 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.78567775 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.72739879 |
| 54 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.71450767 |
| 55 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.70986728 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.70795877 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70313825 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.69137572 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68815576 |
| 60 | Nicotine addiction_Homo sapiens_hsa05033 | 0.67337048 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66059204 |
| 62 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.64118897 |
| 63 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62806618 |
| 64 | Sulfur relay system_Homo sapiens_hsa04122 | 0.62263962 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58518396 |
| 66 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.58168221 |
| 67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.58101992 |
| 68 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.56442936 |
| 69 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55682186 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51396945 |
| 71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51368507 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50453479 |
| 73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50078380 |
| 74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48253536 |
| 75 | Morphine addiction_Homo sapiens_hsa05032 | 0.46992312 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.43524087 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.43345281 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41615171 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.40762105 |
| 80 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.39011994 |
| 81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38174960 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.36766716 |
| 83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.34756059 |
| 84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.34668004 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34185807 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.30725161 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29862927 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.29373056 |
| 89 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.28441374 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.27549174 |
| 91 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.26457137 |
| 92 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26235513 |
| 93 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.22197415 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22054836 |
| 95 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.19548172 |
| 96 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.18301742 |
| 97 | Salivary secretion_Homo sapiens_hsa04970 | 0.15169991 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.14923425 |
| 99 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.14305026 |
| 100 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.14240620 |

