

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | rRNA methylation (GO:0031167) | 8.84008634 |
| 2 | negative regulation of neurotransmitter transport (GO:0051589) | 8.76955006 |
| 3 | positive regulation of vasculogenesis (GO:2001214) | 7.81173166 |
| 4 | rRNA modification (GO:0000154) | 7.45971953 |
| 5 | Rap protein signal transduction (GO:0032486) | 7.01386610 |
| 6 | regulation of establishment of cell polarity (GO:2000114) | 6.93621503 |
| 7 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 5.70036636 |
| 8 | positive regulation of Rap GTPase activity (GO:0032854) | 5.64353665 |
| 9 | regulation of vasculogenesis (GO:2001212) | 5.45197977 |
| 10 | auditory receptor cell stereocilium organization (GO:0060088) | 5.43160925 |
| 11 | regulation of Rap GTPase activity (GO:0032317) | 5.31752980 |
| 12 | response to nerve growth factor (GO:1990089) | 5.30747104 |
| 13 | cellular response to nerve growth factor stimulus (GO:1990090) | 5.30747104 |
| 14 | endocardial cushion development (GO:0003197) | 5.03814250 |
| 15 | negative regulation of granulocyte differentiation (GO:0030853) | 5.01838956 |
| 16 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 4.85537762 |
| 17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.84323712 |
| 18 | heparin metabolic process (GO:0030202) | 4.30387389 |
| 19 | heparin biosynthetic process (GO:0030210) | 4.30387389 |
| 20 | regulation of male gonad development (GO:2000018) | 4.24887880 |
| 21 | negative regulation of norepinephrine secretion (GO:0010700) | 4.20535743 |
| 22 | photoreceptor cell maintenance (GO:0045494) | 4.10036772 |
| 23 | protein neddylation (GO:0045116) | 4.08878680 |
| 24 | DNA double-strand break processing (GO:0000729) | 4.05998707 |
| 25 | inner ear receptor stereocilium organization (GO:0060122) | 4.00739804 |
| 26 | establishment of endothelial barrier (GO:0061028) | 3.98617440 |
| 27 | positive regulation of granulocyte differentiation (GO:0030854) | 3.96241044 |
| 28 | regulation of pigment cell differentiation (GO:0050932) | 3.93684468 |
| 29 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 3.92982445 |
| 30 | response to dietary excess (GO:0002021) | 3.90737608 |
| 31 | cullin deneddylation (GO:0010388) | 3.89930191 |
| 32 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.87138312 |
| 33 | response to pheromone (GO:0019236) | 3.83233062 |
| 34 | regulation of female gonad development (GO:2000194) | 3.82000205 |
| 35 | negative regulation of heart rate (GO:0010459) | 3.67130510 |
| 36 | regulation of synaptic vesicle transport (GO:1902803) | 3.66967535 |
| 37 | negative regulation of exocytosis (GO:0045920) | 3.63990889 |
| 38 | positive regulation of male gonad development (GO:2000020) | 3.63067695 |
| 39 | peripheral nervous system neuron development (GO:0048935) | 3.57147684 |
| 40 | protein deneddylation (GO:0000338) | 3.56732168 |
| 41 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.54420869 |
| 42 | regulation of penile erection (GO:0060405) | 3.53689726 |
| 43 | hematopoietic stem cell proliferation (GO:0071425) | 3.42670387 |
| 44 | definitive hemopoiesis (GO:0060216) | 3.41831663 |
| 45 | regulation of glucokinase activity (GO:0033131) | 3.40788415 |
| 46 | regulation of hexokinase activity (GO:1903299) | 3.40788415 |
| 47 | regulation of tyrosine phosphorylation of Stat3 protein (GO:0042516) | 3.39265025 |
| 48 | ribonucleoprotein complex disassembly (GO:0032988) | 3.39218629 |
| 49 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.35956322 |
| 50 | tachykinin receptor signaling pathway (GO:0007217) | 3.31425673 |
| 51 | cornea development in camera-type eye (GO:0061303) | 3.29698274 |
| 52 | positive regulation of steroid hormone secretion (GO:2000833) | 3.25162932 |
| 53 | left/right pattern formation (GO:0060972) | 3.22354163 |
| 54 | negative regulation of mast cell activation (GO:0033004) | 3.14789360 |
| 55 | positive regulation of protein kinase C signaling (GO:0090037) | 3.14189487 |
| 56 | relaxation of smooth muscle (GO:0044557) | 3.12069115 |
| 57 | vocalization behavior (GO:0071625) | 3.11441441 |
| 58 | negative regulation of catecholamine secretion (GO:0033604) | 3.08521243 |
| 59 | protein-cofactor linkage (GO:0018065) | 3.05187950 |
| 60 | regulation of feeding behavior (GO:0060259) | 3.04750655 |
| 61 | negative regulation of appetite (GO:0032099) | 3.00992637 |
| 62 | negative regulation of response to food (GO:0032096) | 3.00992637 |
| 63 | regulation of developmental pigmentation (GO:0048070) | 3.00582900 |
| 64 | cellular response to arsenic-containing substance (GO:0071243) | 2.98501357 |
| 65 | positive regulation of mitochondrial fission (GO:0090141) | 2.98248438 |
| 66 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 2.96779277 |
| 67 | pseudouridine synthesis (GO:0001522) | 2.95567016 |
| 68 | astrocyte development (GO:0014002) | 2.91625572 |
| 69 | regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418) | 2.90499536 |
| 70 | negative regulation of cell aging (GO:0090344) | 2.88045812 |
| 71 | cranial nerve morphogenesis (GO:0021602) | 2.85179169 |
| 72 | histone H3-K4 trimethylation (GO:0080182) | 2.84856656 |
| 73 | thrombin receptor signaling pathway (GO:0070493) | 2.84027724 |
| 74 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.82206224 |
| 75 | imidazole-containing compound metabolic process (GO:0052803) | 2.81560676 |
| 76 | head development (GO:0060322) | 2.81096377 |
| 77 | positive regulation of receptor internalization (GO:0002092) | 2.80842303 |
| 78 | ubiquinone metabolic process (GO:0006743) | 2.79865019 |
| 79 | developmental pigmentation (GO:0048066) | 2.78577094 |
| 80 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.76796112 |
| 81 | platelet dense granule organization (GO:0060155) | 2.76456694 |
| 82 | embryonic process involved in female pregnancy (GO:0060136) | 2.76231434 |
| 83 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 2.73752975 |
| 84 | ubiquinone biosynthetic process (GO:0006744) | 2.73702346 |
| 85 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.68711536 |
| 86 | quinone metabolic process (GO:1901661) | 2.66290877 |
| 87 | negative regulation of chemokine production (GO:0032682) | 2.64590143 |
| 88 | negative regulation of viral entry into host cell (GO:0046597) | 2.63379072 |
| 89 | negative regulation of synaptic transmission (GO:0050805) | 2.62916134 |
| 90 | lens morphogenesis in camera-type eye (GO:0002089) | 2.60441851 |
| 91 | positive regulation of developmental pigmentation (GO:0048087) | 2.59056337 |
| 92 | left/right axis specification (GO:0070986) | 2.58599103 |
| 93 | nodal signaling pathway (GO:0038092) | 2.57872116 |
| 94 | establishment of protein localization to Golgi (GO:0072600) | 2.57187160 |
| 95 | endothelial cell development (GO:0001885) | 2.56450092 |
| 96 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.55504394 |
| 97 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.55504394 |
| 98 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 11.5858895 |
| 99 | negative regulation of neurotransmitter secretion (GO:0046929) | 10.2701701 |
| 100 | nerve growth factor signaling pathway (GO:0038180) | 10.2656131 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 5.92883140 |
| 2 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 3.83767920 |
| 3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.70307578 |
| 4 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 3.23224770 |
| 5 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 3.06048937 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01412998 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.94339522 |
| 8 | EWS_26573619_Chip-Seq_HEK293_Human | 2.94296845 |
| 9 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.87906869 |
| 10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.56125627 |
| 11 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.48507906 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.39355328 |
| 13 | FUS_26573619_Chip-Seq_HEK293_Human | 2.38750322 |
| 14 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.35472028 |
| 15 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.32528396 |
| 16 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.24981401 |
| 17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.16182415 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.14239599 |
| 19 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 2.04284803 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.04165163 |
| 21 | P300_19829295_ChIP-Seq_ESCs_Human | 2.00451945 |
| 22 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.89409780 |
| 23 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.86868612 |
| 24 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.86200192 |
| 25 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.85836018 |
| 26 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.83936965 |
| 27 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.80203193 |
| 28 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.77898265 |
| 29 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.74709779 |
| 30 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.74277724 |
| 31 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.73206624 |
| 32 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.70026111 |
| 33 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.64364857 |
| 34 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.62549699 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.59286411 |
| 36 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.55221181 |
| 37 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.54237460 |
| 38 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.54004270 |
| 39 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.52622060 |
| 40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.52274948 |
| 41 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.51074386 |
| 42 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.50098534 |
| 43 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.48897322 |
| 44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.48497692 |
| 45 | AR_25329375_ChIP-Seq_VCAP_Human | 1.47682792 |
| 46 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.46924466 |
| 47 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.44897694 |
| 48 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.42412190 |
| 49 | TCF4_23295773_ChIP-Seq_U87_Human | 1.42406309 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40545926 |
| 51 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.40545926 |
| 52 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.38935928 |
| 53 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.38688335 |
| 54 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.38385873 |
| 55 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.37459668 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.35424464 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.35054949 |
| 58 | JUN_21703547_ChIP-Seq_K562_Human | 1.31381205 |
| 59 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.28977614 |
| 60 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.28813687 |
| 61 | STAT3_23295773_ChIP-Seq_U87_Human | 1.26731159 |
| 62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.26078781 |
| 63 | KDM2B_26808549_Chip-Seq_REH_Human | 1.25972853 |
| 64 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.25430127 |
| 65 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.25203510 |
| 66 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.24404506 |
| 67 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.23790754 |
| 68 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.22150974 |
| 69 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.22150974 |
| 70 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.21491678 |
| 71 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20842964 |
| 72 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.20332739 |
| 73 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.19326132 |
| 74 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.17742546 |
| 75 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.17422958 |
| 76 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.16439127 |
| 77 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.14799456 |
| 78 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.13325783 |
| 79 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.13126097 |
| 80 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.12885016 |
| 81 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.10235651 |
| 82 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.08725094 |
| 83 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.08438375 |
| 84 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.06127233 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05616962 |
| 86 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.05324189 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.05324189 |
| 88 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03795713 |
| 89 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.03775482 |
| 90 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03048566 |
| 91 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02304989 |
| 92 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.01771132 |
| 93 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.00457266 |
| 94 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.99627808 |
| 95 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.99451199 |
| 96 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97268503 |
| 97 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.96825939 |
| 98 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.96698692 |
| 99 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.95600341 |
| 100 | GATA1_22025678_ChIP-Seq_K562_Human | 0.95364194 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001188_hyperpigmentation | 5.52796175 |
| 2 | MP0003283_abnormal_digestive_organ | 3.98234737 |
| 3 | MP0005503_abnormal_tendon_morphology | 3.91548945 |
| 4 | MP0002396_abnormal_hematopoietic_system | 3.61712996 |
| 5 | MP0000462_abnormal_digestive_system | 3.52138900 |
| 6 | MP0003279_aneurysm | 3.10076664 |
| 7 | MP0005174_abnormal_tail_pigmentation | 2.86081564 |
| 8 | MP0005645_abnormal_hypothalamus_physiol | 2.68230772 |
| 9 | MP0006054_spinal_hemorrhage | 2.55178128 |
| 10 | MP0009250_abnormal_appendicular_skeleto | 2.43532103 |
| 11 | MP0004147_increased_porphyrin_level | 2.42107769 |
| 12 | MP0004134_abnormal_chest_morphology | 2.37757690 |
| 13 | MP0009384_cardiac_valve_regurgitation | 2.34439308 |
| 14 | MP0009697_abnormal_copulation | 2.34359670 |
| 15 | MP0004133_heterotaxia | 2.27460165 |
| 16 | MP0000015_abnormal_ear_pigmentation | 2.25993247 |
| 17 | MP0003890_abnormal_embryonic-extraembry | 2.17374438 |
| 18 | MP0005275_abnormal_skin_tensile | 2.08377660 |
| 19 | MP0005409_darkened_coat_color | 1.93891002 |
| 20 | MP0003880_abnormal_central_pattern | 1.83916289 |
| 21 | MP0004215_abnormal_myocardial_fiber | 1.81794071 |
| 22 | MP0001299_abnormal_eye_distance/ | 1.74839459 |
| 23 | MP0001348_abnormal_lacrimal_gland | 1.70803491 |
| 24 | MP0003122_maternal_imprinting | 1.69242329 |
| 25 | MP0005464_abnormal_platelet_physiology | 1.68020077 |
| 26 | MP0009379_abnormal_foot_pigmentation | 1.66645008 |
| 27 | MP0005623_abnormal_meninges_morphology | 1.63082568 |
| 28 | MP0004484_altered_response_of | 1.53888860 |
| 29 | MP0005646_abnormal_pituitary_gland | 1.50630789 |
| 30 | MP0008877_abnormal_DNA_methylation | 1.47280691 |
| 31 | MP0002234_abnormal_pharynx_morphology | 1.47048344 |
| 32 | MP0003724_increased_susceptibility_to | 1.46667575 |
| 33 | MP0003119_abnormal_digestive_system | 1.40523087 |
| 34 | MP0004742_abnormal_vestibular_system | 1.37248079 |
| 35 | MP0001529_abnormal_vocalization | 1.36314149 |
| 36 | MP0004808_abnormal_hematopoietic_stem | 1.34692080 |
| 37 | MP0001764_abnormal_homeostasis | 1.27974028 |
| 38 | MP0002095_abnormal_skin_pigmentation | 1.26018469 |
| 39 | MP0002938_white_spotting | 1.21559863 |
| 40 | MP0003656_abnormal_erythrocyte_physiolo | 1.18549396 |
| 41 | MP0003787_abnormal_imprinting | 1.13444273 |
| 42 | MP0005508_abnormal_skeleton_morphology | 1.13287410 |
| 43 | MP0003121_genomic_imprinting | 1.11750127 |
| 44 | MP0000778_abnormal_nervous_system | 1.11001857 |
| 45 | MP0002233_abnormal_nose_morphology | 1.10618430 |
| 46 | MP0005253_abnormal_eye_physiology | 1.08791071 |
| 47 | MP0005075_abnormal_melanosome_morpholog | 1.08154643 |
| 48 | MP0010386_abnormal_urinary_bladder | 1.07303298 |
| 49 | MP0001486_abnormal_startle_reflex | 1.06248455 |
| 50 | MP0003300_gastrointestinal_ulcer | 1.03622270 |
| 51 | MP0005551_abnormal_eye_electrophysiolog | 1.02416338 |
| 52 | MP0004885_abnormal_endolymph | 1.02026980 |
| 53 | MP0000631_abnormal_neuroendocrine_gland | 1.01117118 |
| 54 | MP0004142_abnormal_muscle_tone | 0.94979595 |
| 55 | MP0000858_altered_metastatic_potential | 0.94518877 |
| 56 | MP0006072_abnormal_retinal_apoptosis | 0.94426423 |
| 57 | MP0002734_abnormal_mechanical_nocicepti | 0.92901293 |
| 58 | MP0001270_distended_abdomen | 0.92568470 |
| 59 | MP0004270_analgesia | 0.92482488 |
| 60 | MP0000026_abnormal_inner_ear | 0.92227825 |
| 61 | MP0004084_abnormal_cardiac_muscle | 0.92204784 |
| 62 | MP0003186_abnormal_redox_activity | 0.91677387 |
| 63 | MP0001970_abnormal_pain_threshold | 0.90690245 |
| 64 | MP0002108_abnormal_muscle_morphology | 0.89032433 |
| 65 | MP0000013_abnormal_adipose_tissue | 0.88418679 |
| 66 | MP0002837_dystrophic_cardiac_calcinosis | 0.87758709 |
| 67 | MP0009780_abnormal_chondrocyte_physiolo | 0.87525090 |
| 68 | MP0000049_abnormal_middle_ear | 0.86839589 |
| 69 | MP0005266_abnormal_metabolism | 0.86588590 |
| 70 | MP0001542_abnormal_bone_strength | 0.86105912 |
| 71 | MP0002102_abnormal_ear_morphology | 0.85389414 |
| 72 | MP0008770_decreased_survivor_rate | 0.83995421 |
| 73 | MP0008058_abnormal_DNA_repair | 0.82526002 |
| 74 | MP0001963_abnormal_hearing_physiology | 0.81829468 |
| 75 | MP0005248_abnormal_Harderian_gland | 0.80134837 |
| 76 | MP0005376_homeostasis/metabolism_phenot | 0.79168220 |
| 77 | MP0002177_abnormal_outer_ear | 0.77510047 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.77477807 |
| 79 | MP0002751_abnormal_autonomic_nervous | 0.76277816 |
| 80 | MP0002272_abnormal_nervous_system | 0.76117775 |
| 81 | MP0001915_intracranial_hemorrhage | 0.75093567 |
| 82 | MP0003763_abnormal_thymus_physiology | 0.73417060 |
| 83 | MP0000639_abnormal_adrenal_gland | 0.72734724 |
| 84 | MP0010329_abnormal_lipoprotein_level | 0.72328459 |
| 85 | MP0002114_abnormal_axial_skeleton | 0.71901014 |
| 86 | MP0003755_abnormal_palate_morphology | 0.71711003 |
| 87 | MP0005085_abnormal_gallbladder_physiolo | 0.71592314 |
| 88 | MP0002332_abnormal_exercise_endurance | 0.69749437 |
| 89 | MP0001191_abnormal_skin_condition | 0.65236747 |
| 90 | MP0000163_abnormal_cartilage_morphology | 0.64210897 |
| 91 | MP0002116_abnormal_craniofacial_bone | 0.64160539 |
| 92 | MP0002109_abnormal_limb_morphology | 0.64110489 |
| 93 | MP0001119_abnormal_female_reproductive | 0.63611760 |
| 94 | MP0002115_abnormal_skeleton_extremities | 0.63080258 |
| 95 | MP0002113_abnormal_skeleton_development | 0.62713974 |
| 96 | MP0009053_abnormal_anal_canal | 0.61977135 |
| 97 | MP0001286_abnormal_eye_development | 0.61047011 |
| 98 | MP0002896_abnormal_bone_mineralization | 0.59342644 |
| 99 | MP0005171_absent_coat_pigmentation | 0.59046093 |
| 100 | MP0000538_abnormal_urinary_bladder | 0.57488047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Methylmalonic acidemia (HP:0002912) | 6.25058229 |
| 2 | Homocystinuria (HP:0002156) | 5.79809031 |
| 3 | Abnormality of homocysteine metabolism (HP:0010919) | 5.79809031 |
| 4 | Abnormality of methionine metabolism (HP:0010901) | 5.09513833 |
| 5 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.09034588 |
| 6 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 4.79562726 |
| 7 | Methylmalonic aciduria (HP:0012120) | 4.62041573 |
| 8 | Median cleft lip (HP:0000161) | 4.27643747 |
| 9 | Attenuation of retinal blood vessels (HP:0007843) | 3.95852242 |
| 10 | Abnormality of the frontal sinuses (HP:0002687) | 3.94327544 |
| 11 | Megaloblastic anemia (HP:0001889) | 3.89903059 |
| 12 | Metaphyseal dysplasia (HP:0100255) | 3.84677444 |
| 13 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.84295408 |
| 14 | Atonic seizures (HP:0010819) | 3.81649392 |
| 15 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 3.70945026 |
| 16 | Acute myeloid leukemia (HP:0004808) | 3.70543220 |
| 17 | Chronic hepatic failure (HP:0100626) | 3.62279601 |
| 18 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.59750734 |
| 19 | Decreased central vision (HP:0007663) | 3.58961748 |
| 20 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.47105666 |
| 21 | Lower limb asymmetry (HP:0100559) | 3.40627560 |
| 22 | Long clavicles (HP:0000890) | 3.40110600 |
| 23 | Abnormality of the columella (HP:0009929) | 3.35901023 |
| 24 | Abnormality of vitamin B metabolism (HP:0004340) | 3.31654820 |
| 25 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.27869297 |
| 26 | Volvulus (HP:0002580) | 3.10330709 |
| 27 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.05094516 |
| 28 | Intrahepatic cholestasis (HP:0001406) | 3.03120864 |
| 29 | Split foot (HP:0001839) | 2.93388724 |
| 30 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.88436674 |
| 31 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.88436674 |
| 32 | Genetic anticipation (HP:0003743) | 2.76986676 |
| 33 | Stomach cancer (HP:0012126) | 2.75041869 |
| 34 | Short tibia (HP:0005736) | 2.71944735 |
| 35 | Pancreatic fibrosis (HP:0100732) | 2.71906850 |
| 36 | Large earlobe (HP:0009748) | 2.71569308 |
| 37 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.67931671 |
| 38 | Congenital sensorineural hearing impairment (HP:0008527) | 2.64330040 |
| 39 | Nephronophthisis (HP:0000090) | 2.47818590 |
| 40 | Vitreoretinal degeneration (HP:0000655) | 2.46490943 |
| 41 | Abnormality of the costochondral junction (HP:0000919) | 2.43697733 |
| 42 | Abnormality of the renal medulla (HP:0100957) | 2.43647108 |
| 43 | Fibular hypoplasia (HP:0003038) | 2.41780142 |
| 44 | Epidermoid cyst (HP:0200040) | 2.38829367 |
| 45 | Abnormality of the corticospinal tract (HP:0002492) | 2.38602221 |
| 46 | Ulnar bowing (HP:0003031) | 2.38092990 |
| 47 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.27850124 |
| 48 | Metaphyseal cupping (HP:0003021) | 2.26145376 |
| 49 | Enlarged epiphyses (HP:0010580) | 2.24841106 |
| 50 | Tibial bowing (HP:0002982) | 2.20578300 |
| 51 | Femoral bowing (HP:0002980) | 2.20072904 |
| 52 | Abnormality of vitamin metabolism (HP:0100508) | 2.19684243 |
| 53 | Small hand (HP:0200055) | 2.17863082 |
| 54 | Embryonal renal neoplasm (HP:0011794) | 2.17708067 |
| 55 | Irregular vertebral endplates (HP:0003301) | 2.17295729 |
| 56 | Absent frontal sinuses (HP:0002688) | 2.17181158 |
| 57 | Cerebellar dysplasia (HP:0007033) | 2.15988610 |
| 58 | Arthropathy (HP:0003040) | 2.15290794 |
| 59 | Intestinal atresia (HP:0011100) | 2.10645924 |
| 60 | Abnormality of the renal cortex (HP:0011035) | 2.09966389 |
| 61 | Dicarboxylic aciduria (HP:0003215) | 2.03776089 |
| 62 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.03776089 |
| 63 | Termporal pattern (HP:0011008) | 2.03273757 |
| 64 | Insidious onset (HP:0003587) | 2.03273757 |
| 65 | Mild short stature (HP:0003502) | 2.02371534 |
| 66 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.01758727 |
| 67 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.99896640 |
| 68 | Hypoplastic ischia (HP:0003175) | 1.96996203 |
| 69 | Conjunctival hamartoma (HP:0100780) | 1.96280659 |
| 70 | Molar tooth sign on MRI (HP:0002419) | 1.93892600 |
| 71 | Abnormality of midbrain morphology (HP:0002418) | 1.93892600 |
| 72 | Abnormality of serum amino acid levels (HP:0003112) | 1.93857120 |
| 73 | Heterochromia iridis (HP:0001100) | 1.91807843 |
| 74 | Asymmetric growth (HP:0100555) | 1.89229023 |
| 75 | Embryonal neoplasm (HP:0002898) | 1.88991100 |
| 76 | Abnormality involving the epiphyses of the upper limbs (HP:0003839) | 1.87707958 |
| 77 | Abnormality of the epiphyses of the hand (HP:0005924) | 1.85440799 |
| 78 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.82162851 |
| 79 | Abnormality of the ischium (HP:0003174) | 1.80887857 |
| 80 | Ulnar claw (HP:0001178) | 1.80694157 |
| 81 | Renal cortical cysts (HP:0000803) | 1.80527297 |
| 82 | Prolonged bleeding time (HP:0003010) | 1.77722809 |
| 83 | Pancreatic cysts (HP:0001737) | 1.75566363 |
| 84 | Partial duplication of the phalanx of hand (HP:0009999) | 1.74543228 |
| 85 | Steatorrhea (HP:0002570) | 1.73205681 |
| 86 | Abnormality of the incisor (HP:0000676) | 1.72840449 |
| 87 | Venous insufficiency (HP:0005293) | 1.72113971 |
| 88 | 3-Methylglutaconic aciduria (HP:0003535) | 1.71817941 |
| 89 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.71447733 |
| 90 | Short 4th metacarpal (HP:0010044) | 1.71447733 |
| 91 | Generalized tonic-clonic seizures (HP:0002069) | 1.69689346 |
| 92 | Progressive macrocephaly (HP:0004481) | 1.68588382 |
| 93 | Thickened calvaria (HP:0002684) | 1.67892096 |
| 94 | Prominent nose (HP:0000448) | 1.67878854 |
| 95 | Genu varum (HP:0002970) | 1.67829329 |
| 96 | Irregular epiphyses (HP:0010582) | 1.67322444 |
| 97 | Flat face (HP:0012368) | 1.66896293 |
| 98 | Facial hemangioma (HP:0000329) | 1.65195028 |
| 99 | Focal seizures (HP:0007359) | 1.65117558 |
| 100 | Abnormality of the fibula (HP:0002991) | 1.64525713 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DYRK3 | 3.65179784 |
| 2 | PIK3CG | 3.47034526 |
| 3 | BCR | 3.36013762 |
| 4 | TRIM28 | 3.24232664 |
| 5 | RPS6KA4 | 3.09094817 |
| 6 | SIK3 | 2.91733821 |
| 7 | CDK8 | 2.67959467 |
| 8 | MAP2K7 | 2.65829768 |
| 9 | STK16 | 2.47298772 |
| 10 | CDK6 | 2.22409169 |
| 11 | HIPK2 | 2.14143391 |
| 12 | MAP3K4 | 1.99383535 |
| 13 | BMPR1B | 1.94656171 |
| 14 | BUB1 | 1.89096082 |
| 15 | SGK2 | 1.88043650 |
| 16 | CSNK1G2 | 1.84819018 |
| 17 | FRK | 1.84578499 |
| 18 | MATK | 1.83327489 |
| 19 | KSR1 | 1.83205130 |
| 20 | MAP3K6 | 1.79186160 |
| 21 | FER | 1.78503469 |
| 22 | PIK3CA | 1.72577273 |
| 23 | WNK3 | 1.62317777 |
| 24 | PRKG2 | 1.49643401 |
| 25 | MAPK13 | 1.46052015 |
| 26 | KIT | 1.42161596 |
| 27 | SGK494 | 1.36122625 |
| 28 | SGK223 | 1.36122625 |
| 29 | CSNK1G3 | 1.33400557 |
| 30 | TNIK | 1.31842265 |
| 31 | ACVR1B | 1.23685004 |
| 32 | NTRK3 | 1.20410935 |
| 33 | AKT3 | 1.20140332 |
| 34 | MAP3K3 | 1.18644542 |
| 35 | PDGFRA | 1.18064659 |
| 36 | CSNK1G1 | 1.17516663 |
| 37 | EPHA3 | 1.16739348 |
| 38 | EPHA4 | 1.16700577 |
| 39 | CDK3 | 1.13559152 |
| 40 | CASK | 1.07223590 |
| 41 | CDK9 | 1.06736900 |
| 42 | CAMK4 | 1.04743228 |
| 43 | TXK | 1.00867959 |
| 44 | PRKG1 | 0.99539992 |
| 45 | NEK2 | 0.98702796 |
| 46 | MAP3K5 | 0.93420152 |
| 47 | CAMKK2 | 0.90340074 |
| 48 | RAF1 | 0.89647579 |
| 49 | JAK1 | 0.87703797 |
| 50 | PLK4 | 0.87048052 |
| 51 | NUAK1 | 0.86696378 |
| 52 | STK39 | 0.86295182 |
| 53 | WNK4 | 0.84842143 |
| 54 | CAMK1G | 0.82055148 |
| 55 | CSNK1A1L | 0.78685226 |
| 56 | SRPK1 | 0.75547428 |
| 57 | PNCK | 0.74250497 |
| 58 | ADRBK2 | 0.72838257 |
| 59 | DYRK1A | 0.68691988 |
| 60 | PRKCE | 0.68576554 |
| 61 | SGK3 | 0.68112101 |
| 62 | MARK1 | 0.65644230 |
| 63 | TEC | 0.65080796 |
| 64 | PLK2 | 0.64516844 |
| 65 | MAP3K7 | 0.64111246 |
| 66 | CDC7 | 0.62732011 |
| 67 | MAP2K4 | 0.62633890 |
| 68 | MAP4K2 | 0.60927472 |
| 69 | ERBB3 | 0.58863543 |
| 70 | STK3 | 0.57558011 |
| 71 | TGFBR1 | 0.56800923 |
| 72 | WNK1 | 0.53245107 |
| 73 | PINK1 | 0.52561368 |
| 74 | RET | 0.51718329 |
| 75 | GSK3A | 0.50983005 |
| 76 | PKN1 | 0.50416316 |
| 77 | RPS6KA5 | 0.49174431 |
| 78 | CAMK1D | 0.46319257 |
| 79 | TYRO3 | 0.45818267 |
| 80 | VRK1 | 0.45086444 |
| 81 | MINK1 | 0.44711566 |
| 82 | PRKACG | 0.43738112 |
| 83 | BRD4 | 0.41022102 |
| 84 | MKNK1 | 0.38160220 |
| 85 | CAMK1 | 0.36103570 |
| 86 | PRKACA | 0.35628985 |
| 87 | SGK1 | 0.35579805 |
| 88 | OBSCN | 0.34973758 |
| 89 | NEK6 | 0.34302066 |
| 90 | GRK6 | 0.33692176 |
| 91 | MAP3K2 | 0.31900225 |
| 92 | RPS6KA6 | 0.30369389 |
| 93 | KSR2 | 0.28958563 |
| 94 | PDGFRB | 0.27367995 |
| 95 | RPS6KL1 | 0.27301953 |
| 96 | RPS6KC1 | 0.27301953 |
| 97 | SCYL2 | 0.26999696 |
| 98 | RPS6KA2 | 0.26510800 |
| 99 | CSNK1A1 | 0.26317651 |
| 100 | EIF2AK3 | 0.25147176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.00984615 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.39618241 |
| 3 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 3.20393136 |
| 4 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.48098332 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.44891587 |
| 6 | Taste transduction_Homo sapiens_hsa04742 | 2.33384162 |
| 7 | Platelet activation_Homo sapiens_hsa04611 | 2.20783257 |
| 8 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.17800763 |
| 9 | Circadian entrainment_Homo sapiens_hsa04713 | 1.94659642 |
| 10 | Long-term potentiation_Homo sapiens_hsa04720 | 1.85361453 |
| 11 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.83117038 |
| 12 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.82709747 |
| 13 | Renin secretion_Homo sapiens_hsa04924 | 1.75950035 |
| 14 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.74984534 |
| 15 | Long-term depression_Homo sapiens_hsa04730 | 1.72424703 |
| 16 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.70635657 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.70184677 |
| 18 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.58458078 |
| 19 | Salivary secretion_Homo sapiens_hsa04970 | 1.51843627 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.41760905 |
| 21 | Gap junction_Homo sapiens_hsa04540 | 1.33536786 |
| 22 | Melanoma_Homo sapiens_hsa05218 | 1.31284587 |
| 23 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.26122762 |
| 24 | Cocaine addiction_Homo sapiens_hsa05030 | 1.23311218 |
| 25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.20621180 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.20615238 |
| 27 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.14663009 |
| 28 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.14617546 |
| 29 | Ras signaling pathway_Homo sapiens_hsa04014 | 1.10475606 |
| 30 | Parkinsons disease_Homo sapiens_hsa05012 | 1.10404357 |
| 31 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.10093174 |
| 32 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.09434967 |
| 33 | Insulin secretion_Homo sapiens_hsa04911 | 1.03553874 |
| 34 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.03084351 |
| 35 | Melanogenesis_Homo sapiens_hsa04916 | 1.00979887 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.98169144 |
| 37 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.96417943 |
| 38 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.95700398 |
| 39 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.95419511 |
| 40 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.95363844 |
| 41 | Olfactory transduction_Homo sapiens_hsa04740 | 0.95165532 |
| 42 | Circadian rhythm_Homo sapiens_hsa04710 | 0.95021416 |
| 43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.94019658 |
| 44 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.93206377 |
| 45 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.92564825 |
| 46 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.92315591 |
| 47 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.91979341 |
| 48 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.86333445 |
| 49 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.83753524 |
| 50 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.83080804 |
| 51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.83042468 |
| 52 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.82322472 |
| 53 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.80638679 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79820957 |
| 55 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.79616404 |
| 56 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75546150 |
| 57 | Amoebiasis_Homo sapiens_hsa05146 | 0.75312084 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74666453 |
| 59 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.74225217 |
| 60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.72999261 |
| 61 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72776307 |
| 62 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.71172191 |
| 63 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.71057846 |
| 64 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.70396267 |
| 65 | Glioma_Homo sapiens_hsa05214 | 0.70070935 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.69244971 |
| 67 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.66600753 |
| 68 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.66243315 |
| 69 | Focal adhesion_Homo sapiens_hsa04510 | 0.64181955 |
| 70 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.63959001 |
| 71 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.62849201 |
| 72 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.62058938 |
| 73 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61994497 |
| 74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.61953880 |
| 75 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.60516432 |
| 76 | Alcoholism_Homo sapiens_hsa05034 | 0.59470678 |
| 77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.59263714 |
| 78 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.58932468 |
| 79 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.58600458 |
| 80 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.57564575 |
| 81 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.54656698 |
| 82 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.53667282 |
| 83 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.53293718 |
| 84 | Alzheimers disease_Homo sapiens_hsa05010 | 0.53091046 |
| 85 | Peroxisome_Homo sapiens_hsa04146 | 0.53060476 |
| 86 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.51154946 |
| 87 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50580944 |
| 88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50400291 |
| 89 | Morphine addiction_Homo sapiens_hsa05032 | 0.50383887 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50068855 |
| 91 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.48475210 |
| 92 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.45341785 |
| 93 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.44783560 |
| 94 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.44513229 |
| 95 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.44404151 |
| 96 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42548497 |
| 97 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.41792850 |
| 98 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.41579347 |
| 99 | Huntingtons disease_Homo sapiens_hsa05016 | 0.41406432 |
| 100 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.39638182 |

