

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | thrombin receptor signaling pathway (GO:0070493) | 8.91271034 |
| 2 | protein neddylation (GO:0045116) | 8.27303283 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 7.21190336 |
| 4 | blood coagulation, intrinsic pathway (GO:0007597) | 6.47441634 |
| 5 | regulation of platelet aggregation (GO:0090330) | 6.02954398 |
| 6 | regulation of platelet activation (GO:0010543) | 5.72200568 |
| 7 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.66449223 |
| 8 | negative regulation of heart rate (GO:0010459) | 5.63220870 |
| 9 | negative regulation of thymocyte apoptotic process (GO:0070244) | 5.60898042 |
| 10 | adenosine receptor signaling pathway (GO:0001973) | 5.44368475 |
| 11 | leukocyte migration involved in inflammatory response (GO:0002523) | 5.41026161 |
| 12 | platelet aggregation (GO:0070527) | 5.31987963 |
| 13 | positive regulation of endothelial cell differentiation (GO:0045603) | 5.18180315 |
| 14 | regulation of integrin-mediated signaling pathway (GO:2001044) | 5.15968232 |
| 15 | negative regulation of norepinephrine secretion (GO:0010700) | 5.14180357 |
| 16 | negative regulation of platelet activation (GO:0010544) | 4.99557121 |
| 17 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 4.96212853 |
| 18 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 4.92532206 |
| 19 | positive regulation of mast cell activation (GO:0033005) | 4.85631425 |
| 20 | angiogenesis involved in wound healing (GO:0060055) | 4.75038721 |
| 21 | low-density lipoprotein particle remodeling (GO:0034374) | 4.39006034 |
| 22 | lipoxygenase pathway (GO:0019372) | 4.32269100 |
| 23 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.31669900 |
| 24 | neutrophil activation (GO:0042119) | 4.30913654 |
| 25 | regulation of lipoprotein metabolic process (GO:0050746) | 4.30247865 |
| 26 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.28318066 |
| 27 | negative regulation of response to food (GO:0032096) | 4.24040344 |
| 28 | negative regulation of appetite (GO:0032099) | 4.24040344 |
| 29 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.20339167 |
| 30 | negative regulation of protein localization to cell surface (GO:2000009) | 4.03834416 |
| 31 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.96066472 |
| 32 | platelet degranulation (GO:0002576) | 3.94495957 |
| 33 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.94103331 |
| 34 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.88899528 |
| 35 | polyamine biosynthetic process (GO:0006596) | 3.87114640 |
| 36 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.86163273 |
| 37 | negative regulation of heart contraction (GO:0045822) | 3.80284631 |
| 38 | regulation of endothelial cell differentiation (GO:0045601) | 3.78975270 |
| 39 | platelet activation (GO:0030168) | 3.78730034 |
| 40 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.77706178 |
| 41 | negative regulation of T cell apoptotic process (GO:0070233) | 3.77055326 |
| 42 | granulocyte activation (GO:0036230) | 3.72162693 |
| 43 | regulation of integrin activation (GO:0033623) | 3.70437523 |
| 44 | homotypic cell-cell adhesion (GO:0034109) | 3.67831619 |
| 45 | purinergic receptor signaling pathway (GO:0035587) | 3.63465760 |
| 46 | regulation of norepinephrine secretion (GO:0014061) | 3.63347311 |
| 47 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.61061669 |
| 48 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.58041333 |
| 49 | beta-amyloid metabolic process (GO:0050435) | 3.56811917 |
| 50 | platelet dense granule organization (GO:0060155) | 3.52502121 |
| 51 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.42184683 |
| 52 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.41879967 |
| 53 | positive regulation of macrophage differentiation (GO:0045651) | 3.39060080 |
| 54 | mitochondrial calcium ion transport (GO:0006851) | 3.38934728 |
| 55 | positive regulation of receptor recycling (GO:0001921) | 3.38310824 |
| 56 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.36937161 |
| 57 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.35169560 |
| 58 | platelet formation (GO:0030220) | 3.33836397 |
| 59 | autophagic vacuole fusion (GO:0000046) | 3.33215478 |
| 60 | megakaryocyte development (GO:0035855) | 3.32021994 |
| 61 | negative regulation of catecholamine secretion (GO:0033604) | 3.30772204 |
| 62 | phospholipid homeostasis (GO:0055091) | 3.30520497 |
| 63 | termination of signal transduction (GO:0023021) | 3.30225381 |
| 64 | regulation of female receptivity (GO:0045924) | 3.29449712 |
| 65 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.28188327 |
| 66 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.27268795 |
| 67 | endothelium development (GO:0003158) | 3.22554070 |
| 68 | positive regulation of hemostasis (GO:1900048) | 3.19789181 |
| 69 | positive regulation of blood coagulation (GO:0030194) | 3.19789181 |
| 70 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.19360816 |
| 71 | regulation of cholesterol efflux (GO:0010874) | 3.13484019 |
| 72 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.13177086 |
| 73 | high-density lipoprotein particle remodeling (GO:0034375) | 3.10580489 |
| 74 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.09921417 |
| 75 | extracellular fibril organization (GO:0043206) | 3.07239545 |
| 76 | plasma membrane fusion (GO:0045026) | 3.02196378 |
| 77 | phagocytosis, engulfment (GO:0006911) | 2.99307350 |
| 78 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.97908663 |
| 79 | reverse cholesterol transport (GO:0043691) | 2.97338149 |
| 80 | regulation of sensory perception (GO:0051931) | 2.97234069 |
| 81 | regulation of sensory perception of pain (GO:0051930) | 2.97234069 |
| 82 | negative regulation of blood circulation (GO:1903523) | 2.95706846 |
| 83 | vesicle targeting (GO:0006903) | 2.93142014 |
| 84 | microtubule depolymerization (GO:0007019) | 2.91740683 |
| 85 | mesodermal cell differentiation (GO:0048333) | 2.90473364 |
| 86 | positive regulation of coagulation (GO:0050820) | 2.89357519 |
| 87 | positive regulation of mast cell degranulation (GO:0043306) | 2.89329835 |
| 88 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.89329835 |
| 89 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.89190244 |
| 90 | leukocyte degranulation (GO:0043299) | 2.88172694 |
| 91 | regulation of mast cell activation (GO:0033003) | 2.87713145 |
| 92 | positive regulation of granulocyte differentiation (GO:0030854) | 2.87085446 |
| 93 | relaxation of smooth muscle (GO:0044557) | 2.86808527 |
| 94 | female mating behavior (GO:0060180) | 2.85293050 |
| 95 | regulation of blood coagulation (GO:0030193) | 2.83660068 |
| 96 | regulation of hemostasis (GO:1900046) | 2.83660068 |
| 97 | amine biosynthetic process (GO:0009309) | 2.81268417 |
| 98 | regulation of thymocyte apoptotic process (GO:0070243) | 2.80232357 |
| 99 | regulation of memory T cell differentiation (GO:0043380) | 2.77232048 |
| 100 | monoamine transport (GO:0015844) | 2.75521457 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 4.68894894 |
| 2 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 4.18311747 |
| 3 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.81997940 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.68257426 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.45258557 |
| 6 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.94145646 |
| 7 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.92680976 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.75292472 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.72570328 |
| 10 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.59769248 |
| 11 | GATA1_19941826_ChIP-Seq_K562_Human | 2.54085089 |
| 12 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.31380640 |
| 13 | GATA2_19941826_ChIP-Seq_K562_Human | 2.25573831 |
| 14 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 2.22565685 |
| 15 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.15972009 |
| 16 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.13652762 |
| 17 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.10974250 |
| 18 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 2.05442983 |
| 19 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.02338378 |
| 20 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.02225482 |
| 21 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.98628368 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.97458797 |
| 23 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.94702997 |
| 24 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.93549937 |
| 25 | SPI1_23127762_ChIP-Seq_K562_Human | 1.93222120 |
| 26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.80977164 |
| 27 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.77382391 |
| 28 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.76106518 |
| 29 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.72675960 |
| 30 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.70400656 |
| 31 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.68895228 |
| 32 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62842407 |
| 33 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.53981487 |
| 34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.49439002 |
| 35 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.45379819 |
| 36 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.44332003 |
| 37 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.43694866 |
| 38 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.43401040 |
| 39 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.42376461 |
| 40 | VDR_22108803_ChIP-Seq_LS180_Human | 1.42095514 |
| 41 | GATA1_22025678_ChIP-Seq_K562_Human | 1.39548651 |
| 42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33059383 |
| 43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.28679868 |
| 44 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.22896783 |
| 45 | EWS_26573619_Chip-Seq_HEK293_Human | 1.22433690 |
| 46 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.21817413 |
| 47 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.21817413 |
| 48 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.18502652 |
| 49 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.17990784 |
| 50 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.17977002 |
| 51 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.17761014 |
| 52 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16908977 |
| 53 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.15752544 |
| 54 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.14762580 |
| 55 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.14022800 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13513827 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.12694150 |
| 58 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.11464152 |
| 59 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11108710 |
| 60 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.08968924 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04918045 |
| 62 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04650763 |
| 63 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.04252486 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.03360401 |
| 65 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.01664929 |
| 66 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01543121 |
| 67 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01543121 |
| 68 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.01470495 |
| 69 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.01361851 |
| 70 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.99977439 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98747266 |
| 72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.97747414 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94671935 |
| 74 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.92331259 |
| 75 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91754367 |
| 76 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.90918190 |
| 77 | P300_19829295_ChIP-Seq_ESCs_Human | 0.90436891 |
| 78 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.89876733 |
| 79 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.88495936 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 0.87437303 |
| 81 | GATA3_26560356_Chip-Seq_TH2_Human | 0.87064698 |
| 82 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.86810019 |
| 83 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.85908116 |
| 84 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.85781959 |
| 85 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.82285624 |
| 86 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.81517045 |
| 87 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.81501628 |
| 88 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.81332889 |
| 89 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.81163466 |
| 90 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.80353276 |
| 91 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.79493939 |
| 92 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.78968466 |
| 93 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.78495239 |
| 94 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.78432035 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.77827324 |
| 96 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.77243575 |
| 97 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.76696757 |
| 98 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.76628568 |
| 99 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.75458978 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.75180976 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008004_abnormal_stomach_pH | 5.21353469 |
| 2 | MP0003724_increased_susceptibility_to | 3.48765261 |
| 3 | MP0000465_gastrointestinal_hemorrhage | 3.45874165 |
| 4 | MP0004510_myositis | 3.00482168 |
| 5 | MP0005083_abnormal_biliary_tract | 2.76264193 |
| 6 | MP0004084_abnormal_cardiac_muscle | 2.54416866 |
| 7 | MP0002736_abnormal_nociception_after | 2.52037959 |
| 8 | MP0000230_abnormal_systemic_arterial | 2.44137057 |
| 9 | MP0000343_altered_response_to | 2.20080632 |
| 10 | MP0001879_abnormal_lymphatic_vessel | 2.20033420 |
| 11 | MP0008775_abnormal_heart_ventricle | 2.11757642 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.05653457 |
| 13 | MP0005464_abnormal_platelet_physiology | 10.1628349 |
| 14 | MP0001835_abnormal_antigen_presentation | 1.95376384 |
| 15 | MP0003566_abnormal_cell_adhesion | 1.94267537 |
| 16 | MP0005167_abnormal_blood-brain_barrier | 1.78379403 |
| 17 | MP0003638_abnormal_response/metabolism_ | 1.77603297 |
| 18 | MP0008872_abnormal_physiological_respon | 1.76184416 |
| 19 | MP0003303_peritoneal_inflammation | 1.75446767 |
| 20 | MP0004036_abnormal_muscle_relaxation | 1.69138144 |
| 21 | MP0005671_abnormal_response_to | 1.67705966 |
| 22 | MP0005410_abnormal_fertilization | 1.64577395 |
| 23 | MP0004130_abnormal_muscle_cell | 1.64530038 |
| 24 | MP0003828_pulmonary_edema | 1.63564607 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.61897809 |
| 26 | MP0003879_abnormal_hair_cell | 1.59762195 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 1.48249936 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.45977891 |
| 29 | MP0010155_abnormal_intestine_physiology | 1.37723876 |
| 30 | MP0002733_abnormal_thermal_nociception | 1.36555712 |
| 31 | MP0005058_abnormal_lysosome_morphology | 1.35580379 |
| 32 | MP0006276_abnormal_autonomic_nervous | 1.33673105 |
| 33 | MP0005000_abnormal_immune_tolerance | 1.33051319 |
| 34 | MP0000249_abnormal_blood_vessel | 1.32636326 |
| 35 | MP0001851_eye_inflammation | 1.27543813 |
| 36 | MP0002398_abnormal_bone_marrow | 1.27380994 |
| 37 | MP0004215_abnormal_myocardial_fiber | 1.26152971 |
| 38 | MP0001663_abnormal_digestive_system | 1.24801709 |
| 39 | MP0009697_abnormal_copulation | 1.23171889 |
| 40 | MP0005174_abnormal_tail_pigmentation | 1.20145473 |
| 41 | MP0010329_abnormal_lipoprotein_level | 1.19959993 |
| 42 | MP0003136_yellow_coat_color | 1.13450847 |
| 43 | MP0009763_increased_sensitivity_to | 1.13113730 |
| 44 | MP0009764_decreased_sensitivity_to | 1.11672477 |
| 45 | MP0000015_abnormal_ear_pigmentation | 1.10903315 |
| 46 | MP0004484_altered_response_of | 1.10082320 |
| 47 | MP0002132_abnormal_respiratory_system | 1.08633369 |
| 48 | MP0004947_skin_inflammation | 1.07714963 |
| 49 | MP0002723_abnormal_immune_serum | 1.04695761 |
| 50 | MP0001970_abnormal_pain_threshold | 1.04583624 |
| 51 | MP0000383_abnormal_hair_follicle | 1.03614039 |
| 52 | MP0003866_abnormal_defecation | 1.01910301 |
| 53 | MP0002102_abnormal_ear_morphology | 1.01579225 |
| 54 | MP0001800_abnormal_humoral_immune | 0.99939182 |
| 55 | MP0003011_delayed_dark_adaptation | 0.96749347 |
| 56 | MP0010368_abnormal_lymphatic_system | 0.94481123 |
| 57 | MP0005248_abnormal_Harderian_gland | 0.94345225 |
| 58 | MP0002972_abnormal_cardiac_muscle | 0.92677872 |
| 59 | MP0002452_abnormal_antigen_presenting | 0.92200292 |
| 60 | MP0000689_abnormal_spleen_morphology | 0.91996415 |
| 61 | MP0009642_abnormal_blood_homeostasis | 0.90922167 |
| 62 | MP0005165_increased_susceptibility_to | 0.90199072 |
| 63 | MP0001533_abnormal_skeleton_physiology | 0.89341029 |
| 64 | MP0006054_spinal_hemorrhage | 0.87663055 |
| 65 | MP0002429_abnormal_blood_cell | 0.87527884 |
| 66 | MP0001544_abnormal_cardiovascular_syste | 0.86621070 |
| 67 | MP0005385_cardiovascular_system_phenoty | 0.86621070 |
| 68 | MP0006138_congestive_heart_failure | 0.86098270 |
| 69 | MP0008874_decreased_physiological_sensi | 0.83616307 |
| 70 | MP0009765_abnormal_xenobiotic_induced | 0.81912444 |
| 71 | MP0005620_abnormal_muscle_contractility | 0.81554342 |
| 72 | MP0002420_abnormal_adaptive_immunity | 0.81115991 |
| 73 | MP0003436_decreased_susceptibility_to | 0.80972138 |
| 74 | MP0009780_abnormal_chondrocyte_physiolo | 0.80198987 |
| 75 | MP0005381_digestive/alimentary_phenotyp | 0.79580583 |
| 76 | MP0001819_abnormal_immune_cell | 0.79487183 |
| 77 | MP0004134_abnormal_chest_morphology | 0.77111238 |
| 78 | MP0005387_immune_system_phenotype | 0.76991219 |
| 79 | MP0001790_abnormal_immune_system | 0.76991219 |
| 80 | MP0000858_altered_metastatic_potential | 0.76805555 |
| 81 | MP0001756_abnormal_urination | 0.76682076 |
| 82 | MP0001845_abnormal_inflammatory_respons | 0.76395730 |
| 83 | MP0002722_abnormal_immune_system | 0.76357381 |
| 84 | MP0001545_abnormal_hematopoietic_system | 0.75679144 |
| 85 | MP0005397_hematopoietic_system_phenotyp | 0.75679144 |
| 86 | MP0006036_abnormal_mitochondrial_physio | 0.74851016 |
| 87 | MP0003656_abnormal_erythrocyte_physiolo | 0.74727268 |
| 88 | MP0001765_abnormal_ion_homeostasis | 0.74335174 |
| 89 | MP0004085_abnormal_heartbeat | 0.73841438 |
| 90 | MP0000716_abnormal_immune_system | 0.73318602 |
| 91 | MP0001664_abnormal_digestion | 0.73034139 |
| 92 | MP0004142_abnormal_muscle_tone | 0.72007119 |
| 93 | MP0002653_abnormal_ependyma_morphology | 0.71168536 |
| 94 | MP0005535_abnormal_body_temperature | 0.70959346 |
| 95 | MP0000685_abnormal_immune_system | 0.68124421 |
| 96 | MP0006035_abnormal_mitochondrial_morpho | 0.66543993 |
| 97 | MP0002128_abnormal_blood_circulation | 0.65740489 |
| 98 | MP0002419_abnormal_innate_immunity | 0.64466343 |
| 99 | MP0004883_abnormal_blood_vessel | 0.61270772 |
| 100 | MP0009333_abnormal_splenocyte_physiolog | 0.59617465 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Petechiae (HP:0000967) | 9.97874487 |
| 2 | Purpura (HP:0000979) | 9.46953226 |
| 3 | Epistaxis (HP:0000421) | 7.67353826 |
| 4 | Gingival bleeding (HP:0000225) | 6.57172816 |
| 5 | Hyperlipoproteinemia (HP:0010980) | 6.19946717 |
| 6 | Abnormal platelet function (HP:0011869) | 5.56630908 |
| 7 | Impaired platelet aggregation (HP:0003540) | 5.56630908 |
| 8 | Poikilocytosis (HP:0004447) | 4.20672786 |
| 9 | Dyschromatopsia (HP:0007641) | 4.05909669 |
| 10 | Spontaneous hematomas (HP:0007420) | 4.05159498 |
| 11 | Acanthocytosis (HP:0001927) | 3.92048154 |
| 12 | Conjunctival telangiectasia (HP:0000524) | 3.59919701 |
| 13 | Bruising susceptibility (HP:0000978) | 3.26239075 |
| 14 | Abnormality of lateral ventricle (HP:0030047) | 3.24905580 |
| 15 | Abnormal pupillary function (HP:0007686) | 3.20503678 |
| 16 | Abnormality of the common coagulation pathway (HP:0010990) | 3.19125268 |
| 17 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 3.08592229 |
| 18 | Increased density of long bones (HP:0006392) | 2.94089631 |
| 19 | Paralysis (HP:0003470) | 2.92089447 |
| 20 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.77932461 |
| 21 | Xanthomatosis (HP:0000991) | 2.60922800 |
| 22 | Decreased central vision (HP:0007663) | 2.60751678 |
| 23 | Stomatitis (HP:0010280) | 2.58890994 |
| 24 | Increased IgM level (HP:0003496) | 2.46637843 |
| 25 | Abnormal auditory evoked potentials (HP:0006958) | 2.46003069 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.31742355 |
| 27 | Upper limb muscle weakness (HP:0003484) | 2.28553303 |
| 28 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.27978118 |
| 29 | Hepatosplenomegaly (HP:0001433) | 2.21432669 |
| 30 | Joint swelling (HP:0001386) | 2.21380070 |
| 31 | Joint hemorrhage (HP:0005261) | 2.15379129 |
| 32 | Hyperthyroidism (HP:0000836) | 2.08975210 |
| 33 | Tinnitus (HP:0000360) | 2.08131085 |
| 34 | Thyroid-stimulating hormone excess (HP:0002925) | 2.02221081 |
| 35 | Nausea (HP:0002018) | 2.00670481 |
| 36 | Prolonged bleeding time (HP:0003010) | 12.0411271 |
| 37 | Menorrhagia (HP:0000132) | 11.3586067 |
| 38 | Increased mean platelet volume (HP:0011877) | 11.1491311 |
| 39 | Abnormal platelet volume (HP:0011876) | 10.4499066 |
| 40 | Papillary thyroid carcinoma (HP:0002895) | 1.98322476 |
| 41 | Abnormality of macrophages (HP:0004311) | 1.97772315 |
| 42 | Abnormality of alanine metabolism (HP:0010916) | 1.95329987 |
| 43 | Hyperalaninemia (HP:0003348) | 1.95329987 |
| 44 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.95329987 |
| 45 | Ventricular fibrillation (HP:0001663) | 1.94961420 |
| 46 | Abnormal ciliary motility (HP:0012262) | 1.91771579 |
| 47 | Abnormality of iron homeostasis (HP:0011031) | 1.91401049 |
| 48 | Spontaneous abortion (HP:0005268) | 1.86907301 |
| 49 | Encephalitis (HP:0002383) | 1.86562793 |
| 50 | Male infertility (HP:0003251) | 1.84331225 |
| 51 | Episodic fever (HP:0001954) | 1.83118621 |
| 52 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.81160407 |
| 53 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.81160407 |
| 54 | Generalized aminoaciduria (HP:0002909) | 1.77881513 |
| 55 | Autoimmune hemolytic anemia (HP:0001890) | 1.74827052 |
| 56 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.70015009 |
| 57 | Tongue fasciculations (HP:0001308) | 1.67162348 |
| 58 | Hypophosphatemic rickets (HP:0004912) | 1.65073399 |
| 59 | Basal ganglia calcification (HP:0002135) | 1.63690445 |
| 60 | Distal lower limb amyotrophy (HP:0008944) | 1.61948242 |
| 61 | Dysautonomia (HP:0002459) | 1.61683040 |
| 62 | Exertional dyspnea (HP:0002875) | 1.61011304 |
| 63 | Arterial thrombosis (HP:0004420) | 1.58636270 |
| 64 | Polyphagia (HP:0002591) | 1.58127584 |
| 65 | Uterine leiomyosarcoma (HP:0002891) | 1.56757577 |
| 66 | Leiomyosarcoma (HP:0100243) | 1.56757577 |
| 67 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.56066186 |
| 68 | Muscle fibrillation (HP:0010546) | 1.55542634 |
| 69 | Polycythemia (HP:0001901) | 1.53490304 |
| 70 | Infertility (HP:0000789) | 1.53445804 |
| 71 | Arthropathy (HP:0003040) | 1.52821439 |
| 72 | Abnormality of binocular vision (HP:0011514) | 1.52671561 |
| 73 | Diplopia (HP:0000651) | 1.52671561 |
| 74 | Obstructive lung disease (HP:0006536) | 1.50368704 |
| 75 | Chronic obstructive pulmonary disease (HP:0006510) | 1.50368704 |
| 76 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.49124948 |
| 77 | Increased serum ferritin (HP:0003281) | 1.48059908 |
| 78 | Back pain (HP:0003418) | 1.47480469 |
| 79 | Congenital sensorineural hearing impairment (HP:0008527) | 1.46053961 |
| 80 | Renal Fanconi syndrome (HP:0001994) | 1.45339395 |
| 81 | Vertigo (HP:0002321) | 1.42553255 |
| 82 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.42299458 |
| 83 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.40777451 |
| 84 | Absent/shortened dynein arms (HP:0200106) | 1.40777451 |
| 85 | Bladder carcinoma (HP:0002862) | 1.40738997 |
| 86 | Bladder neoplasm (HP:0009725) | 1.40738997 |
| 87 | Testicular neoplasm (HP:0010788) | 1.39534695 |
| 88 | Thyroid carcinoma (HP:0002890) | 1.36890273 |
| 89 | Biliary tract neoplasm (HP:0100574) | 1.35250093 |
| 90 | Intellectual disability, profound (HP:0002187) | 1.34668312 |
| 91 | Myocardial infarction (HP:0001658) | 1.33682399 |
| 92 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.33016438 |
| 93 | Abnormality of the prostate (HP:0008775) | 1.32954846 |
| 94 | Central scotoma (HP:0000603) | 1.24748141 |
| 95 | Lower limb amyotrophy (HP:0007210) | 1.24449173 |
| 96 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.23895197 |
| 97 | Eosinophilia (HP:0001880) | 1.22562513 |
| 98 | Leukocytosis (HP:0001974) | 1.22155550 |
| 99 | Abnormality of the renal cortex (HP:0011035) | 1.22002957 |
| 100 | Thrombocytosis (HP:0001894) | 1.21546625 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 5.15674391 |
| 2 | RIPK4 | 4.77867715 |
| 3 | BMX | 4.23842385 |
| 4 | MYLK | 3.61420143 |
| 5 | EIF2AK1 | 3.06548446 |
| 6 | TEC | 2.94924838 |
| 7 | BTK | 2.73774332 |
| 8 | PTK2B | 2.67314736 |
| 9 | GRK5 | 2.17022825 |
| 10 | PIK3CG | 2.15941618 |
| 11 | SYK | 2.10534381 |
| 12 | ADRBK2 | 2.05269104 |
| 13 | PNCK | 1.94015132 |
| 14 | TAOK3 | 1.92951145 |
| 15 | BMPR2 | 1.89077053 |
| 16 | ILK | 1.87595954 |
| 17 | CSF1R | 1.84579877 |
| 18 | ZAP70 | 1.70990629 |
| 19 | GRK6 | 1.69426373 |
| 20 | ACVR1B | 1.61971457 |
| 21 | STK3 | 1.58818910 |
| 22 | TNIK | 1.53351778 |
| 23 | FGR | 1.37373237 |
| 24 | CAMKK2 | 1.32233021 |
| 25 | TLK1 | 1.30602383 |
| 26 | HCK | 1.28452313 |
| 27 | PLK2 | 1.26227067 |
| 28 | STK24 | 1.23925625 |
| 29 | MAPKAPK3 | 1.19641762 |
| 30 | TNK2 | 1.17415832 |
| 31 | DAPK3 | 1.11608077 |
| 32 | PIM2 | 1.10269964 |
| 33 | BMPR1B | 1.06821043 |
| 34 | FES | 1.06622963 |
| 35 | PAK1 | 1.03486760 |
| 36 | SIK3 | 1.03182898 |
| 37 | TXK | 1.01089628 |
| 38 | ADRBK1 | 0.99941601 |
| 39 | IKBKB | 0.99783372 |
| 40 | LYN | 0.97141952 |
| 41 | MATK | 0.97008634 |
| 42 | DAPK2 | 0.89039069 |
| 43 | BLK | 0.87992029 |
| 44 | MAP3K12 | 0.85871421 |
| 45 | NUAK1 | 0.85756869 |
| 46 | ITK | 0.84981903 |
| 47 | LMTK2 | 0.83422919 |
| 48 | MAP4K2 | 0.81421319 |
| 49 | TRIM28 | 0.81247452 |
| 50 | MINK1 | 0.80793477 |
| 51 | ERBB2 | 0.79594070 |
| 52 | GRK1 | 0.78459338 |
| 53 | MAPK13 | 0.76436025 |
| 54 | MAP3K5 | 0.76172594 |
| 55 | CSK | 0.72724177 |
| 56 | EPHB2 | 0.68523403 |
| 57 | PAK3 | 0.66304091 |
| 58 | IRAK1 | 0.65963110 |
| 59 | PRKD1 | 0.63394215 |
| 60 | MARK3 | 0.63370639 |
| 61 | PDGFRB | 0.62655795 |
| 62 | STK16 | 0.59697191 |
| 63 | PKN1 | 0.58799864 |
| 64 | PDK1 | 0.57392929 |
| 65 | EPHA3 | 0.55068773 |
| 66 | TESK2 | 0.54998540 |
| 67 | PRKACG | 0.52637382 |
| 68 | RET | 0.50895525 |
| 69 | DYRK2 | 0.48121613 |
| 70 | ROCK1 | 0.46787557 |
| 71 | DAPK1 | 0.46704051 |
| 72 | DYRK1B | 0.45309249 |
| 73 | TYRO3 | 0.45102729 |
| 74 | MAP2K3 | 0.44553035 |
| 75 | TAOK2 | 0.43737331 |
| 76 | PRKG1 | 0.43322109 |
| 77 | PRKCQ | 0.41268646 |
| 78 | PINK1 | 0.40137897 |
| 79 | ZAK | 0.40101464 |
| 80 | LCK | 0.39710281 |
| 81 | TAOK1 | 0.39360709 |
| 82 | STK4 | 0.39227195 |
| 83 | PDPK1 | 0.39087838 |
| 84 | MAP3K11 | 0.38916680 |
| 85 | FER | 0.38216367 |
| 86 | FYN | 0.37556940 |
| 87 | JAK2 | 0.36516587 |
| 88 | DYRK3 | 0.35720533 |
| 89 | BRSK2 | 0.35514900 |
| 90 | MAPK12 | 0.35212882 |
| 91 | MAP2K1 | 0.33455844 |
| 92 | FRK | 0.33416493 |
| 93 | IGF1R | 0.30677747 |
| 94 | KDR | 0.30567118 |
| 95 | PRKCD | 0.30481092 |
| 96 | PRKCB | 0.29775209 |
| 97 | PRKCA | 0.29530049 |
| 98 | DYRK1A | 0.28513684 |
| 99 | YES1 | 0.26650488 |
| 100 | SRC | 0.26225419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.82609748 |
| 2 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 3.73715736 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.93366869 |
| 4 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.58260705 |
| 5 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.51140348 |
| 6 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.40010159 |
| 7 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.33144218 |
| 8 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.29606229 |
| 9 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 2.00082051 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.94269100 |
| 11 | Gap junction_Homo sapiens_hsa04540 | 1.90801522 |
| 12 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.84964765 |
| 13 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.83533719 |
| 14 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.81595592 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.57457997 |
| 16 | Alcoholism_Homo sapiens_hsa05034 | 1.48912269 |
| 17 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.41662412 |
| 18 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.39590126 |
| 19 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.37060306 |
| 20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.30465406 |
| 21 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.29320945 |
| 22 | Endocytosis_Homo sapiens_hsa04144 | 1.27430984 |
| 23 | Olfactory transduction_Homo sapiens_hsa04740 | 1.25860996 |
| 24 | Long-term depression_Homo sapiens_hsa04730 | 1.16377352 |
| 25 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.14239955 |
| 26 | Circadian entrainment_Homo sapiens_hsa04713 | 1.13196575 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.13079389 |
| 28 | Shigellosis_Homo sapiens_hsa05131 | 1.10272500 |
| 29 | Morphine addiction_Homo sapiens_hsa05032 | 1.07433246 |
| 30 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.07417770 |
| 31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.07219685 |
| 32 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.06591983 |
| 33 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.99777690 |
| 34 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.98687890 |
| 35 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.98442493 |
| 36 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.96177962 |
| 37 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.92112808 |
| 38 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.89929997 |
| 39 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.89160628 |
| 40 | Phagosome_Homo sapiens_hsa04145 | 0.87631124 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84054874 |
| 42 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.83379739 |
| 43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82445630 |
| 44 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.81163231 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 0.80660108 |
| 46 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80181555 |
| 47 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.78595198 |
| 48 | Malaria_Homo sapiens_hsa05144 | 0.75835125 |
| 49 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.75709314 |
| 50 | Focal adhesion_Homo sapiens_hsa04510 | 0.75076782 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71529484 |
| 52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.71267161 |
| 53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.70658939 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.69655297 |
| 55 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.69331956 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67912577 |
| 57 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.67317035 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.67275920 |
| 59 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.65683443 |
| 60 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.62976167 |
| 61 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.62710380 |
| 62 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.62705059 |
| 63 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.60328477 |
| 64 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.58789959 |
| 65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.58533636 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56727279 |
| 67 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.54275329 |
| 68 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.54070171 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.53756596 |
| 70 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.53346829 |
| 71 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.50830254 |
| 72 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.49745632 |
| 73 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.49177131 |
| 74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.48929593 |
| 75 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.48147460 |
| 76 | Mismatch repair_Homo sapiens_hsa03430 | 0.47643982 |
| 77 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.46248165 |
| 78 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.45896288 |
| 79 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.45732627 |
| 80 | Salivary secretion_Homo sapiens_hsa04970 | 0.45210634 |
| 81 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.45175222 |
| 82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.44461169 |
| 83 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.43296300 |
| 84 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42858825 |
| 85 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41773202 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41164160 |
| 87 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.39600367 |
| 88 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.39312706 |
| 89 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38596636 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.37064610 |
| 91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36495340 |
| 92 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.36277662 |
| 93 | Melanoma_Homo sapiens_hsa05218 | 0.34526864 |
| 94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.31507855 |
| 95 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31369074 |
| 96 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.30600936 |
| 97 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.29709432 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.28904312 |
| 99 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.28672005 |
| 100 | Salmonella infection_Homo sapiens_hsa05132 | 0.28544619 |

