PTPRCAP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.45233253
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.95539401
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.95539401
4negative regulation of cell killing (GO:0031342)5.92657427
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.92657427
6positive regulation of gamma-delta T cell activation (GO:0046645)5.69629880
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.57285273
8viral transcription (GO:0019083)5.31952301
9antigen processing and presentation of endogenous antigen (GO:0019883)5.21891086
10translational termination (GO:0006415)5.08766265
11DNA deamination (GO:0045006)5.00476480
12antigen processing and presentation via MHC class Ib (GO:0002475)4.85225559
13positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.85138088
14regulation of gamma-delta T cell differentiation (GO:0045586)4.51286049
15translational elongation (GO:0006414)4.49188884
16ribosomal small subunit biogenesis (GO:0042274)4.45648211
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.40720792
18cytidine metabolic process (GO:0046087)4.40045791
19cytidine catabolic process (GO:0006216)4.40045791
20cytidine deamination (GO:0009972)4.40045791
21cotranslational protein targeting to membrane (GO:0006613)4.30077146
22protein targeting to ER (GO:0045047)4.27853881
23positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.17702712
24regulation of gamma-delta T cell activation (GO:0046643)4.09560225
25protein localization to endoplasmic reticulum (GO:0070972)4.09441964
26establishment of protein localization to endoplasmic reticulum (GO:0072599)4.07397556
27pyrimidine ribonucleoside catabolic process (GO:0046133)4.02544347
28nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.02049890
29maturation of SSU-rRNA (GO:0030490)3.98106767
30viral life cycle (GO:0019058)3.93919885
31regulation of natural killer cell mediated immunity (GO:0002715)3.93667094
32regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.93667094
33cellular protein complex disassembly (GO:0043624)3.83537174
34positive regulation of B cell differentiation (GO:0045579)3.82245405
35B cell receptor signaling pathway (GO:0050853)3.69291338
36regulation of B cell differentiation (GO:0045577)3.67101017
37negative T cell selection (GO:0043383)3.65488982
38positive regulation of alpha-beta T cell proliferation (GO:0046641)3.65224227
39response to interleukin-15 (GO:0070672)3.65048670
40negative thymic T cell selection (GO:0045060)3.64667236
41B cell mediated immunity (GO:0019724)3.63277928
42regulation of B cell receptor signaling pathway (GO:0050855)3.63248322
43regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.62247043
44translational initiation (GO:0006413)3.61386035
45regulation of T cell tolerance induction (GO:0002664)3.60525368
46negative regulation of lymphocyte mediated immunity (GO:0002707)3.60138775
47detection of bacterium (GO:0016045)3.59676617
48T cell homeostasis (GO:0043029)3.55255371
49regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.54697074
50mast cell activation (GO:0045576)3.52686963
51response to interferon-beta (GO:0035456)3.51745962
52positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.49955127
53cellular response to interleukin-15 (GO:0071350)3.49931261
54negative regulation of erythrocyte differentiation (GO:0045647)3.49094376
55Arp2/3 complex-mediated actin nucleation (GO:0034314)3.47413474
56protein complex disassembly (GO:0043241)3.46815725
57regulation of leukocyte mediated cytotoxicity (GO:0001910)3.45014388
58positive thymic T cell selection (GO:0045059)3.44218772
59negative regulation of leukocyte mediated immunity (GO:0002704)3.42176506
60leukocyte aggregation (GO:0070486)3.41248323
61platelet dense granule organization (GO:0060155)3.39338380
62tolerance induction (GO:0002507)3.38190684
63regulation of antigen processing and presentation (GO:0002577)3.36894518
64detection of other organism (GO:0098543)3.36019851
65definitive hemopoiesis (GO:0060216)3.35061216
66regulation of T cell receptor signaling pathway (GO:0050856)3.32284272
67telomere maintenance via semi-conservative replication (GO:0032201)3.31580007
68positive regulation of natural killer cell mediated immunity (GO:0002717)3.31280730
69regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.28694127
70positive regulation of cell killing (GO:0031343)3.27001725
71defense response to protozoan (GO:0042832)3.26736464
72mature B cell differentiation involved in immune response (GO:0002313)3.26469487
73lymph node development (GO:0048535)3.24432130
74macromolecular complex disassembly (GO:0032984)3.23655006
75positive regulation of antigen processing and presentation (GO:0002579)3.22157072
76regulation of cell killing (GO:0031341)3.21638450
77activated T cell proliferation (GO:0050798)3.20610641
78regulation of tolerance induction (GO:0002643)3.20325738
79regulation of interleukin-2 biosynthetic process (GO:0045076)3.19595582
80antigen receptor-mediated signaling pathway (GO:0050851)3.18300860
81negative regulation of T cell mediated immunity (GO:0002710)3.17435957
82interferon-gamma production (GO:0032609)3.17219129
83Peyers patch development (GO:0048541)3.16546050
84mucosal-associated lymphoid tissue development (GO:0048537)3.16546050
85regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.15997853
86regulation of dendritic cell antigen processing and presentation (GO:0002604)3.15890952
87lymphocyte migration (GO:0072676)3.13937625
88interferon-gamma-mediated signaling pathway (GO:0060333)3.13647773
89positive regulation of granulocyte differentiation (GO:0030854)3.13620759
90T cell migration (GO:0072678)3.13051016
91response to protozoan (GO:0001562)3.12937148
92actin nucleation (GO:0045010)3.12877565
93nuclear-transcribed mRNA catabolic process (GO:0000956)3.12596429
94regulation of isotype switching to IgG isotypes (GO:0048302)3.11630092
95regulation of regulatory T cell differentiation (GO:0045589)3.08138878
96DNA strand elongation involved in DNA replication (GO:0006271)3.07551893
97response to type I interferon (GO:0034340)3.07410610
98modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.07226708
99positive regulation by organism of defense response of other organism involved in symbiotic interact3.07226708
100modulation by symbiont of host immune response (GO:0052553)3.07226708
101positive regulation by symbiont of host defense response (GO:0052509)3.07226708
102modulation by symbiont of host defense response (GO:0052031)3.07226708
103modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.07226708
104type I interferon signaling pathway (GO:0060337)3.06319259
105cellular response to type I interferon (GO:0071357)3.06319259
106respiratory burst (GO:0045730)3.05063042
107megakaryocyte development (GO:0035855)3.04239449
108negative regulation of T cell apoptotic process (GO:0070233)3.03422334
109positive regulation of calcium-mediated signaling (GO:0050850)3.02171467
110negative regulation of innate immune response (GO:0045824)3.02170166
111positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.00955794
112T cell receptor signaling pathway (GO:0050852)3.00345180
113mRNA catabolic process (GO:0006402)2.99102249
114mast cell activation involved in immune response (GO:0002279)2.98742204
115mast cell degranulation (GO:0043303)2.98742204
116lymphoid progenitor cell differentiation (GO:0002320)2.98382858
117DNA strand elongation (GO:0022616)2.97762631
118positive regulation of tolerance induction (GO:0002645)2.97750189
119regulation of T cell mediated cytotoxicity (GO:0001914)2.96796584
120mature B cell differentiation (GO:0002335)2.96197153
121thymic T cell selection (GO:0045061)2.95793970
122regulation of alpha-beta T cell activation (GO:0046634)2.92903628
123negative regulation of phagocytosis (GO:0050765)2.91626736
124positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.90533724
125CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.90499395
126neutrophil activation involved in immune response (GO:0002283)2.90226923
127negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.88899679
128deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.85885008
129negative regulation of viral genome replication (GO:0045071)2.85165669
130lymphocyte homeostasis (GO:0002260)2.84766427
131ribosomal large subunit biogenesis (GO:0042273)2.84474890
132RNA catabolic process (GO:0006401)2.82722015
133positive regulation of T cell mediated cytotoxicity (GO:0001916)2.81667345
134telomere maintenance via recombination (GO:0000722)2.81655495
135cellular response to interferon-beta (GO:0035458)2.80956532
136protein targeting to membrane (GO:0006612)2.80943979
137leukocyte homeostasis (GO:0001776)2.80869783
138regulation of interleukin-12 biosynthetic process (GO:0045075)2.78896501
139T cell selection (GO:0045058)2.75750917
140positive regulation of lamellipodium assembly (GO:0010592)2.74683475
141positive T cell selection (GO:0043368)2.73546822
142lymphocyte costimulation (GO:0031294)2.73353543
143myeloid dendritic cell activation (GO:0001773)2.73201718
144T cell costimulation (GO:0031295)2.70989351
145regulation of type I interferon-mediated signaling pathway (GO:0060338)2.70539079
146regulation of alpha-beta T cell proliferation (GO:0046640)2.66468123
147ribonucleoprotein complex biogenesis (GO:0022613)2.64806507
148immunoglobulin mediated immune response (GO:0016064)2.64591549
149NIK/NF-kappaB signaling (GO:0038061)2.64391981

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.82602765
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.82898751
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.41863066
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.26432091
5MYC_22102868_ChIP-Seq_BL_Human3.08678997
6SCL_19346495_ChIP-Seq_HPC-7_Human3.06936511
7* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.98349493
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.94642547
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.94341207
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.93340946
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.89343354
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.86676859
13RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.78836960
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.66235361
15FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.58321316
16TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.56670343
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.43758481
18VDR_21846776_ChIP-Seq_THP-1_Human2.42279071
19STAT4_19710469_ChIP-ChIP_TH1__Mouse2.32228674
20NOTCH1_21737748_ChIP-Seq_TLL_Human2.31753262
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.30466263
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.29970113
23MYB_26560356_Chip-Seq_TH2_Human2.18740510
24* SPI1_23547873_ChIP-Seq_NB4_Human2.10983949
25* MAF_26560356_Chip-Seq_TH1_Human2.04995193
26VDR_23849224_ChIP-Seq_CD4+_Human2.02256981
27GABP_17652178_ChIP-ChIP_JURKAT_Human2.01527639
28SFPI1_20887958_ChIP-Seq_HPC-7_Mouse2.01125235
29ERG_20887958_ChIP-Seq_HPC-7_Mouse1.99461406
30IRF8_21731497_ChIP-ChIP_J774_Mouse1.97108204
31EST1_17652178_ChIP-ChIP_JURKAT_Human1.93029256
32* UTX_26944678_Chip-Seq_JUKART_Human1.92831586
33* MYB_26560356_Chip-Seq_TH1_Human1.92372862
34JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.90958688
35HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.89958115
36FOXP3_21729870_ChIP-Seq_TREG_Human1.89532090
37MYC_18358816_ChIP-ChIP_MESCs_Mouse1.88949721
38FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.88703101
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.86066857
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.82445995
41ETS1_20019798_ChIP-Seq_JURKAT_Human1.80970762
42RUNX_20019798_ChIP-Seq_JUKART_Human1.80968960
43RUNX1_22412390_ChIP-Seq_EML_Mouse1.79944637
44MYB_21317192_ChIP-Seq_ERMYB_Mouse1.79021310
45E2F4_17652178_ChIP-ChIP_JURKAT_Human1.76580129
46MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.75298177
47* CIITA_25753668_ChIP-Seq_RAJI_Human1.73673504
48VDR_24763502_ChIP-Seq_THP-1_Human1.72649771
49LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.67459912
50XRN2_22483619_ChIP-Seq_HELA_Human1.64223224
51GATA3_26560356_Chip-Seq_TH2_Human1.64169023
52STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.63647413
53GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.62973751
54MYC_19079543_ChIP-ChIP_MESCs_Mouse1.62526677
55BCL6_27268052_Chip-Seq_Bcells_Human1.60906278
56MYC_19030024_ChIP-ChIP_MESCs_Mouse1.59722871
57EGR1_19374776_ChIP-ChIP_THP-1_Human1.59556377
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58132324
59LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.52940726
60* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.51791171
61MAF_26560356_Chip-Seq_TH2_Human1.49060204
62TCF7_22412390_ChIP-Seq_EML_Mouse1.48275483
63KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.47247955
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.46624493
65GATA1_22383799_ChIP-Seq_G1ME_Mouse1.45109059
66GATA2_22383799_ChIP-Seq_G1ME_Mouse1.44652864
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43966087
68BP1_19119308_ChIP-ChIP_Hs578T_Human1.40073209
69NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39148584
70ELF1_20517297_ChIP-Seq_JURKAT_Human1.36111154
71GABP_19822575_ChIP-Seq_HepG2_Human1.35766623
72BCOR_27268052_Chip-Seq_Bcells_Human1.32802185
73KDM2B_26808549_Chip-Seq_DND41_Human1.32348634
74SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.31250974
75VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.30490530
76RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.29393157
77* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.28895794
78SRF_21415370_ChIP-Seq_HL-1_Mouse1.27919422
79FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.26509898
80BRD4_27068464_Chip-Seq_AML-cells_Mouse1.25535588
81GATA1_22025678_ChIP-Seq_K562_Human1.24326136
82HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23284427
83NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22971437
84RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.20821458
85IRF8_27001747_Chip-Seq_BMDM_Mouse1.20542429
86GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.20225240
87CREB1_15753290_ChIP-ChIP_HEK293T_Human1.20007385
88DCP1A_22483619_ChIP-Seq_HELA_Human1.19859500
89NELFA_20434984_ChIP-Seq_ESCs_Mouse1.19537479
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19529701
91LXR_22292898_ChIP-Seq_THP-1_Human1.19193070
92E2F1_18555785_ChIP-Seq_MESCs_Mouse1.18009859
93CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16585418
94GATA3_27048872_Chip-Seq_THYMUS_Human1.16581305
95* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.15305724
96TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12726463
97ELK1_19687146_ChIP-ChIP_HELA_Human1.12613435
98TTF2_22483619_ChIP-Seq_HELA_Human1.12124851
99P300_27268052_Chip-Seq_Bcells_Human1.11294339
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.10878561
101THAP11_20581084_ChIP-Seq_MESCs_Mouse1.09892800
102SPI1_23127762_ChIP-Seq_K562_Human1.06684912
103CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06574497
104EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.06221134
105CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06029164
106FOXM1_23109430_ChIP-Seq_U2OS_Human1.05337795
107KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.04610921
108FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04014149
109IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02817829
110* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02584246
111P68_20966046_ChIP-Seq_HELA_Human1.02265600
112ZFX_18555785_ChIP-Seq_MESCs_Mouse1.01842222
113E2F1_21310950_ChIP-Seq_MCF-7_Human1.01732405
114PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01203581
115* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.99766201
116SPI1_20517297_ChIP-Seq_HL60_Human0.98437216
117RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.97093637
118* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96933425
119CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95273025
120YY1_22570637_ChIP-Seq_MALME-3M_Human0.94855983
121GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93026938
122PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92613552
123CTCF_26484167_Chip-Seq_Bcells_Mouse0.92285948
124CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90623743
125E2F1_20622854_ChIP-Seq_HELA_Human0.89565636
126CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89496029
127ELK3_25401928_ChIP-Seq_HUVEC_Human0.89327976
128GATA1_19941827_ChIP-Seq_MEL_Mouse0.88798439
129YY1_21170310_ChIP-Seq_MESCs_Mouse0.88673437
130E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.88516076
131* SA1_27219007_Chip-Seq_ERYTHROID_Human0.87168939
132GATA1_19941826_ChIP-Seq_K562_Human0.85524920
133* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.85454929
134RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84966557
135STAT6_21828071_ChIP-Seq_BEAS2B_Human0.83694969
136RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.82895267
137* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.81690229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.14755745
2MP0001835_abnormal_antigen_presentation4.06964972
3MP0005671_abnormal_response_to3.90115450
4MP0000685_abnormal_immune_system3.77984884
5MP0002396_abnormal_hematopoietic_system3.75344156
6MP0001800_abnormal_humoral_immune3.13387870
7MP0009785_altered_susceptibility_to3.08490219
8* MP0002398_abnormal_bone_marrow2.86660128
9MP0002166_altered_tumor_susceptibility2.72643608
10* MP0002420_abnormal_adaptive_immunity2.69397305
11MP0002723_abnormal_immune_serum2.66363561
12MP0005387_immune_system_phenotype2.64436772
13MP0001790_abnormal_immune_system2.64436772
14* MP0001819_abnormal_immune_cell2.64383121
15* MP0002452_abnormal_antigen_presenting2.60674673
16MP0005000_abnormal_immune_tolerance2.56550627
17MP0005025_abnormal_response_to2.55225179
18MP0000689_abnormal_spleen_morphology2.43616490
19MP0004808_abnormal_hematopoietic_stem2.43373855
20* MP0000716_abnormal_immune_system2.42753705
21* MP0002722_abnormal_immune_system2.34254756
22MP0001873_stomach_inflammation2.26957917
23MP0009333_abnormal_splenocyte_physiolog2.22801912
24MP0000703_abnormal_thymus_morphology2.20989852
25MP0005464_abnormal_platelet_physiology2.20592710
26MP0005075_abnormal_melanosome_morpholog2.16132698
27* MP0002429_abnormal_blood_cell2.13497738
28MP0002006_tumorigenesis2.13159343
29MP0003866_abnormal_defecation2.09865563
30MP0003436_decreased_susceptibility_to2.07569888
31MP0010155_abnormal_intestine_physiology2.07236327
32MP0005397_hematopoietic_system_phenotyp2.02914353
33MP0001545_abnormal_hematopoietic_system2.02914353
34MP0003724_increased_susceptibility_to2.00605484
35MP0002405_respiratory_system_inflammati1.97109909
36MP0005174_abnormal_tail_pigmentation1.92864668
37MP0000490_abnormal_crypts_of1.91674505
38MP0002148_abnormal_hypersensitivity_rea1.91350586
39MP0002419_abnormal_innate_immunity1.82155494
40MP0000465_gastrointestinal_hemorrhage1.76493118
41MP0001853_heart_inflammation1.75320316
42MP0003693_abnormal_embryo_hatching1.70060798
43MP0010094_abnormal_chromosome_stability1.60513978
44MP0002095_abnormal_skin_pigmentation1.58267090
45MP0001845_abnormal_inflammatory_respons1.54237393
46MP0002933_joint_inflammation1.50692134
47MP0008057_abnormal_DNA_replication1.49610672
48MP0006082_CNS_inflammation1.48038134
49MP0002138_abnormal_hepatobiliary_system1.46818609
50MP0008007_abnormal_cellular_replicative1.43846425
51MP0002019_abnormal_tumor_incidence1.38740003
52MP0003077_abnormal_cell_cycle1.38527815
53MP0004947_skin_inflammation1.38435764
54MP0008058_abnormal_DNA_repair1.37662216
55MP0004957_abnormal_blastocyst_morpholog1.36255668
56MP0005645_abnormal_hypothalamus_physiol1.35488368
57MP0009379_abnormal_foot_pigmentation1.32981097
58MP0002132_abnormal_respiratory_system1.19291766
59MP0008469_abnormal_protein_level1.17229230
60MP0000015_abnormal_ear_pigmentation1.10344117
61MP0000858_altered_metastatic_potential1.05245038
62MP0006054_spinal_hemorrhage1.05154001
63MP0003300_gastrointestinal_ulcer1.02629713
64MP0005310_abnormal_salivary_gland1.01732051
65MP0009278_abnormal_bone_marrow1.00512041
66MP0003111_abnormal_nucleus_morphology0.98735283
67MP0003045_fibrosis0.98203857
68MP0003806_abnormal_nucleotide_metabolis0.94809700
69MP0003183_abnormal_peptide_metabolism0.92885284
70MP0000313_abnormal_cell_death0.90934359
71MP0001986_abnormal_taste_sensitivity0.89996026
72MP0002277_abnormal_respiratory_mucosa0.89642496
73MP0004510_myositis0.87929772
74MP0004147_increased_porphyrin_level0.87917198
75MP0005166_decreased_susceptibility_to0.84677158
76MP0003943_abnormal_hepatobiliary_system0.84046055
77MP0004381_abnormal_hair_follicle0.80398739
78MP0003303_peritoneal_inflammation0.78744459
79MP0000477_abnormal_intestine_morphology0.78516833
80MP0001533_abnormal_skeleton_physiology0.77769665
81MP0002998_abnormal_bone_remodeling0.75231885
82MP0003786_premature_aging0.75161721
83MP0005451_abnormal_body_composition0.74801566
84MP0001663_abnormal_digestive_system0.69926360
85MP0009763_increased_sensitivity_to0.68141991
86MP0006036_abnormal_mitochondrial_physio0.65946759
87MP0009765_abnormal_xenobiotic_induced0.65221474
88MP0002693_abnormal_pancreas_physiology0.63860969
89MP0001348_abnormal_lacrimal_gland0.63332084
90MP0003075_altered_response_to0.63058300
91MP0010352_gastrointestinal_tract_polyps0.62238599
92MP0005390_skeleton_phenotype0.62223487
93MP0003656_abnormal_erythrocyte_physiolo0.61763812
94MP0003172_abnormal_lysosome_physiology0.60125269
95MP0009764_decreased_sensitivity_to0.55877440
96MP0003191_abnormal_cellular_cholesterol0.55337019
97MP0000604_amyloidosis0.54731797
98MP0003448_altered_tumor_morphology0.53455345
99MP0000372_irregular_coat_pigmentation0.53272890
100MP0003252_abnormal_bile_duct0.51962054
101MP0002136_abnormal_kidney_physiology0.51775297
102MP0006292_abnormal_olfactory_placode0.51590446
103MP0000350_abnormal_cell_proliferation0.50394500
104MP0000249_abnormal_blood_vessel0.49824624
105MP0002075_abnormal_coat/hair_pigmentati0.48914797
106MP0003795_abnormal_bone_structure0.48394168
107MP0009643_abnormal_urine_homeostasis0.47653722
108MP0001851_eye_inflammation0.47324894
109MP0001765_abnormal_ion_homeostasis0.46942779
110MP0002009_preneoplasia0.46897209
111MP0000598_abnormal_liver_morphology0.46720925
112MP0009840_abnormal_foam_cell0.45881082
113MP0000371_diluted_coat_color0.44562710
114MP0008873_increased_physiological_sensi0.44164969
115MP0005381_digestive/alimentary_phenotyp0.44132964
116MP0008872_abnormal_physiological_respon0.43471827
117MP0004883_abnormal_blood_vessel0.43449830
118MP0005023_abnormal_wound_healing0.43177136
119MP0009642_abnormal_blood_homeostasis0.43061525
120MP0002083_premature_death0.42429364
121MP0001764_abnormal_homeostasis0.41079747
122MP0003186_abnormal_redox_activity0.40271417
123MP0008874_decreased_physiological_sensi0.39956850
124MP0005584_abnormal_enzyme/coenzyme_acti0.39695134
125MP0000681_abnormal_thyroid_gland0.39306216
126MP0002163_abnormal_gland_morphology0.38548716
127MP0008260_abnormal_autophagy0.37085585
128MP0000609_abnormal_liver_physiology0.37059871
129MP0002653_abnormal_ependyma_morphology0.35256227

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)5.54958533
2Recurrent bronchitis (HP:0002837)5.19727251
3Elevated erythrocyte sedimentation rate (HP:0003565)4.96405172
4Chronic otitis media (HP:0000389)4.77237321
5Thrombocytosis (HP:0001894)4.74009656
6Agammaglobulinemia (HP:0004432)4.38410217
7Panhypogammaglobulinemia (HP:0003139)4.36018396
8Abnormality of cells of the erythroid lineage (HP:0012130)4.29028157
9Abnormal number of erythroid precursors (HP:0012131)4.20349409
10Aplastic anemia (HP:0001915)4.02673292
11IgG deficiency (HP:0004315)3.99664443
12Abnormality of B cell number (HP:0010975)3.98216560
13B lymphocytopenia (HP:0010976)3.98216560
14Abnormality of macrophages (HP:0004311)3.98192167
15Abnormality of T cells (HP:0002843)3.96827589
16Myositis (HP:0100614)3.85701248
17T lymphocytopenia (HP:0005403)3.81812722
18Chronic obstructive pulmonary disease (HP:0006510)3.81208497
19Obstructive lung disease (HP:0006536)3.81208497
20Increased IgM level (HP:0003496)3.78604381
21Severe combined immunodeficiency (HP:0004430)3.75857887
22Abnormality of T cell physiology (HP:0011840)3.75434024
23Recurrent viral infections (HP:0004429)3.64550168
24Abnormality of T cell number (HP:0011839)3.62211144
25Reticulocytopenia (HP:0001896)3.61382868
26Nasal polyposis (HP:0100582)3.60808899
27Lymphopenia (HP:0001888)3.52983445
28Abnormal delayed hypersensitivity skin test (HP:0002963)3.52081355
29Retrobulbar optic neuritis (HP:0100654)3.43108280
30Optic neuritis (HP:0100653)3.43108280
31Abnormality of the nasal mucosa (HP:0000433)3.40589146
32Abnormality of cells of the lymphoid lineage (HP:0012140)3.38844860
33Combined immunodeficiency (HP:0005387)3.37802367
34Thyroiditis (HP:0100646)3.37240345
35Meningitis (HP:0001287)3.31164512
36Recurrent fungal infections (HP:0002841)3.29767554
37Petechiae (HP:0000967)3.27209125
38Prolonged bleeding time (HP:0003010)3.16175436
39Cellulitis (HP:0100658)3.12988153
40Gastrointestinal infarctions (HP:0005244)3.11553638
41Abnormality of the prostate (HP:0008775)3.09081597
42Pulmonary infiltrates (HP:0002113)3.05600942
43Bronchitis (HP:0012387)3.05119920
44Gastrointestinal stroma tumor (HP:0100723)3.04382388
45Recurrent sinusitis (HP:0011108)3.02714989
46Recurrent gram-negative bacterial infections (HP:0005420)3.01016996
47Chest pain (HP:0100749)2.96352710
48Hypoplasia of the thymus (HP:0000778)2.96231143
49Lymphoma (HP:0002665)2.94342846
50Gastrointestinal inflammation (HP:0004386)2.93415050
51Chronic sinusitis (HP:0011109)2.91825607
52Recurrent cutaneous fungal infections (HP:0011370)2.89550814
53Chronic mucocutaneous candidiasis (HP:0002728)2.89550814
54Recurrent abscess formation (HP:0002722)2.86189479
55Inflammation of the large intestine (HP:0002037)2.84894857
56Muscle fiber atrophy (HP:0100295)2.82569869
57Urticaria (HP:0001025)2.79559480
58Poikiloderma (HP:0001029)2.77157354
59Pallor (HP:0000980)2.73212183
60Type 2 muscle fiber atrophy (HP:0003554)2.72644323
61Epistaxis (HP:0000421)2.60506589
62Keratoconjunctivitis sicca (HP:0001097)2.58484035
63Vasculitis (HP:0002633)2.55617924
64Sepsis (HP:0100806)2.55409961
65Autoimmune hemolytic anemia (HP:0001890)2.55087526
66Chronic diarrhea (HP:0002028)2.53356878
67Keratoconjunctivitis (HP:0001096)2.51722800
68Eczematoid dermatitis (HP:0000976)2.48157781
69Hypoproteinemia (HP:0003075)2.47952076
70Macrocytic anemia (HP:0001972)2.47621762
71Abnormality of eosinophils (HP:0001879)2.46414220
72Hemoptysis (HP:0002105)2.45280789
73Recurrent bacterial skin infections (HP:0005406)2.41078310
74Abnormality of the pleura (HP:0002103)2.39552139
75Recurrent skin infections (HP:0001581)2.39386407
76Granulocytopenia (HP:0001913)2.39044942
77IgA deficiency (HP:0002720)2.38922200
78Papilloma (HP:0012740)2.38668656
79Verrucae (HP:0200043)2.38668656
80Encephalitis (HP:0002383)2.38069340
81Amaurosis fugax (HP:0100576)2.35732784
82Basal cell carcinoma (HP:0002671)2.32077091
83Pustule (HP:0200039)2.31055466
84Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.30433185
85Decreased activity of mitochondrial respiratory chain (HP:0008972)2.30433185
86Microcytic anemia (HP:0001935)2.29682028
87Colitis (HP:0002583)2.27845992
88Abnormality of the fingertips (HP:0001211)2.26452539
89Type I transferrin isoform profile (HP:0003642)2.25975536
90Abnormal platelet function (HP:0011869)2.25930412
91Impaired platelet aggregation (HP:0003540)2.25930412
92Joint swelling (HP:0001386)2.25234730
93Pulmonary embolism (HP:0002204)2.25047724
94Spontaneous hematomas (HP:0007420)2.24499359
95Leukocytosis (HP:0001974)2.23655708
96Hypochromic anemia (HP:0001931)2.23370313
97Prostate neoplasm (HP:0100787)2.22706447
98Reduced antithrombin III activity (HP:0001976)2.22692157
99Acute hepatic failure (HP:0006554)2.21870880
100Neutropenia (HP:0001875)2.20084355
101Recurrent pneumonia (HP:0006532)2.19884306
102Increased IgE level (HP:0003212)2.19355738
103Hypergammaglobulinemia (HP:0010702)2.17892127
104Osteomyelitis (HP:0002754)2.17266987
105Pancytopenia (HP:0001876)2.15612842
106Restrictive lung disease (HP:0002091)2.14913380
107Recurrent lower respiratory tract infections (HP:0002783)2.14789503
108Abnormality of the heme biosynthetic pathway (HP:0010472)2.13265983
109Skin rash (HP:0000988)2.11766107
110Gingivitis (HP:0000230)2.11601478
111Mediastinal lymphadenopathy (HP:0100721)2.10798470
112Stomatitis (HP:0010280)2.09745270
113Entropion (HP:0000621)2.09383245
114Gangrene (HP:0100758)2.05797784
115Interstitial pulmonary disease (HP:0006530)2.05045095
116Myelodysplasia (HP:0002863)2.04503335
117Arterial thrombosis (HP:0004420)2.03862032
118Fatigue (HP:0012378)2.03370543
119Eosinophilia (HP:0001880)2.02283448
120Emphysema (HP:0002097)2.02006767
121Colon cancer (HP:0003003)2.01513340
122Skin ulcer (HP:0200042)2.01082467
123Acute lymphatic leukemia (HP:0006721)2.00590200
124Autoimmune thrombocytopenia (HP:0001973)2.00119097
125Recurrent otitis media (HP:0000403)1.99689034
126Abnormal protein glycosylation (HP:0012346)1.99412559
127Abnormal glycosylation (HP:0012345)1.99412559
128Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.99412559
129Abnormal protein N-linked glycosylation (HP:0012347)1.99412559
130Orchitis (HP:0100796)1.97337426
131Gingival bleeding (HP:0000225)1.95561343
132Arthralgia (HP:0002829)1.92792207
133Absent rod-and cone-mediated responses on ERG (HP:0007688)1.91998176
134Pulmonary fibrosis (HP:0002206)1.91997686

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.06476594
2TXK3.08398078
3RIPK42.95559150
4NME22.91869587
5KIT2.79133659
6ZAP702.72553261
7EEF2K2.51124026
8BTK2.36177866
9KDR2.31544151
10JAK32.26105731
11TEC2.17185614
12FLT32.14356844
13STK162.02037212
14IKBKE1.99122196
15CSF1R1.94073218
16SYK1.88975723
17TBK11.77983029
18BLK1.73290954
19TGFBR11.71274992
20NLK1.64704342
21GRK61.64526771
22TYK21.63618013
23MAP3K121.63067294
24MAP3K101.59571308
25ACVR1B1.58963149
26TNIK1.57246628
27PRPF4B1.53352513
28TESK21.50831181
29CDK191.48178733
30LCK1.45709852
31WEE11.43700801
32ITK1.35978385
33STK101.29151992
34LRRK21.27515040
35MUSK1.25811593
36RPS6KB21.24196394
37PIM21.21580966
38IRAK41.20293111
39SCYL21.19570905
40LYN1.18179002
41MAP2K31.12285123
42TGFBR21.12135346
43IKBKB1.08522402
44ERN11.08100251
45TNK21.05113401
46FES1.04864572
47FGFR41.00836901
48RPS6KA41.00000083
49PIM10.97883466
50VRK20.96102320
51HCK0.93716490
52CLK10.93256677
53VRK10.91235239
54PASK0.89637405
55NEK20.89575880
56DYRK30.88766744
57EIF2AK10.88704698
58BUB10.88228734
59EIF2AK30.86676586
60CDC70.85093214
61MAPKAPK30.84953945
62PKN20.82852908
63ADRBK20.82073808
64JAK20.81420540
65JAK10.81026366
66MARK30.80166085
67MAP2K20.79802674
68MAP3K140.78420407
69CDK40.77592733
70BMPR20.77057696
71TLK10.76853979
72SMG10.76768635
73PDK10.68869274
74MAP3K10.68087492
75FYN0.67718229
76PRKD20.65925947
77CCNB10.65361503
78MATK0.65110268
79MAP3K130.64753668
80MAP2K60.64510921
81MAP3K70.63755826
82BRSK20.63588415
83SIK30.62186486
84TAOK20.61791374
85CDK80.61719578
86ZAK0.58441058
87ATR0.58067861
88MAPK110.57657521
89HIPK20.57027770
90CSK0.56582749
91TESK10.56222376
92EPHB10.55779550
93PIK3CG0.55681687
94CAMKK10.55402402
95MAPK40.55053009
96DAPK10.54929255
97GRK70.54294856
98SIK20.53990119
99FGFR30.53838152
100MYLK0.53797800
101SRPK10.53697523
102PRKCH0.52631015
103TAOK10.52601945
104MAPKAPK50.51476944
105CDK70.51109908
106FGR0.51052448
107PRKG20.50900156
108ILK0.50605480
109TAOK30.50251919
110MKNK10.49783618
111RAF10.48031841
112MAPK120.46695606
113MST40.45925723
114MAP3K30.45177115
115TIE10.44846605
116CHUK0.42490194
117MAP3K110.41588924
118MAPKAPK20.41226095
119AURKB0.39785878
120CAMK10.39606898
121DYRK1B0.37092013
122STK40.36342469
123CAMKK20.34656962
124RPS6KA50.33675945
125NUAK10.33576802
126PRKCQ0.33095553
127BCKDK0.33075955
128INSR0.30677418
129RPS6KA60.30673739
130ABL10.30537966
131MAPK70.30508950
132MAPK30.30142023
133MAP3K50.30114970
134RPS6KC10.29674536
135RPS6KL10.29674536
136PRKCD0.27412232
137PDPK10.23292674
138IGF1R0.20309498

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.86037850
2Ribosome_Homo sapiens_hsa030104.34577114
3DNA replication_Homo sapiens_hsa030303.76217567
4Ras signaling pathway_Homo sapiens_hsa040143.28732843
5Type I diabetes mellitus_Homo sapiens_hsa049403.13879661
6Mismatch repair_Homo sapiens_hsa034302.92794837
7Base excision repair_Homo sapiens_hsa034102.57871322
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.25012167
9B cell receptor signaling pathway_Homo sapiens_hsa046622.21332237
10Antigen processing and presentation_Homo sapiens_hsa046122.18108002
11Staphylococcus aureus infection_Homo sapiens_hsa051502.14978633
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.14189577
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.11006652
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.08887306
15Measles_Homo sapiens_hsa051622.02558407
16Homologous recombination_Homo sapiens_hsa034401.98985209
17Spliceosome_Homo sapiens_hsa030401.97450364
18Hematopoietic cell lineage_Homo sapiens_hsa046401.96754238
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.89656382
20Nucleotide excision repair_Homo sapiens_hsa034201.88112025
21T cell receptor signaling pathway_Homo sapiens_hsa046601.86005571
22Non-homologous end-joining_Homo sapiens_hsa034501.84915067
23Proteasome_Homo sapiens_hsa030501.83425519
24Pyrimidine metabolism_Homo sapiens_hsa002401.78230842
25RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.63135004
26Herpes simplex infection_Homo sapiens_hsa051681.62046112
27RNA polymerase_Homo sapiens_hsa030201.61402232
28Leishmaniasis_Homo sapiens_hsa051401.53357749
29Allograft rejection_Homo sapiens_hsa053301.50503938
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.44915834
31Rheumatoid arthritis_Homo sapiens_hsa053231.41776653
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.41342059
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.30458667
34RNA degradation_Homo sapiens_hsa030181.22692722
35Shigellosis_Homo sapiens_hsa051311.22145371
36Acute myeloid leukemia_Homo sapiens_hsa052211.17660736
37Osteoclast differentiation_Homo sapiens_hsa043801.14524873
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.12318399
39Sulfur relay system_Homo sapiens_hsa041221.08417189
40Caffeine metabolism_Homo sapiens_hsa002321.07112928
41Cell cycle_Homo sapiens_hsa041101.02086419
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.01357228
43Protein export_Homo sapiens_hsa030601.00226636
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.00076910
45Graft-versus-host disease_Homo sapiens_hsa053320.98977466
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.96209873
47Fanconi anemia pathway_Homo sapiens_hsa034600.96039760
48RNA transport_Homo sapiens_hsa030130.95263159
49Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95144338
50Platelet activation_Homo sapiens_hsa046110.93670264
51Asthma_Homo sapiens_hsa053100.92657596
52Hepatitis B_Homo sapiens_hsa051610.90503317
53Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88190622
54Epstein-Barr virus infection_Homo sapiens_hsa051690.88111520
55p53 signaling pathway_Homo sapiens_hsa041150.86706277
56Toll-like receptor signaling pathway_Homo sapiens_hsa046200.86702977
57NOD-like receptor signaling pathway_Homo sapiens_hsa046210.85156516
58Purine metabolism_Homo sapiens_hsa002300.83763649
59Influenza A_Homo sapiens_hsa051640.82631400
60Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80844577
61N-Glycan biosynthesis_Homo sapiens_hsa005100.80347618
62Legionellosis_Homo sapiens_hsa051340.79708453
63Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.79212412
64Apoptosis_Homo sapiens_hsa042100.78592148
65HTLV-I infection_Homo sapiens_hsa051660.78146948
66Basal transcription factors_Homo sapiens_hsa030220.74221232
67Viral myocarditis_Homo sapiens_hsa054160.72121854
68Pentose phosphate pathway_Homo sapiens_hsa000300.71296528
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71221073
70Autoimmune thyroid disease_Homo sapiens_hsa053200.70812870
71Other glycan degradation_Homo sapiens_hsa005110.69732301
72Toxoplasmosis_Homo sapiens_hsa051450.69378130
73Viral carcinogenesis_Homo sapiens_hsa052030.68689376
74African trypanosomiasis_Homo sapiens_hsa051430.67990170
75Leukocyte transendothelial migration_Homo sapiens_hsa046700.67110785
76Thyroid cancer_Homo sapiens_hsa052160.65692236
77Systemic lupus erythematosus_Homo sapiens_hsa053220.64572621
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62746095
79Chemokine signaling pathway_Homo sapiens_hsa040620.62741752
80One carbon pool by folate_Homo sapiens_hsa006700.61669971
81Pertussis_Homo sapiens_hsa051330.59711470
82Phagosome_Homo sapiens_hsa041450.58354645
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58207437
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57780121
85Folate biosynthesis_Homo sapiens_hsa007900.56805502
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54614799
87Drug metabolism - other enzymes_Homo sapiens_hsa009830.54406097
88Malaria_Homo sapiens_hsa051440.53488277
89Chronic myeloid leukemia_Homo sapiens_hsa052200.52746891
90Salmonella infection_Homo sapiens_hsa051320.51301623
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.48664529
92TNF signaling pathway_Homo sapiens_hsa046680.45007723
93Pancreatic cancer_Homo sapiens_hsa052120.44344113
94Tuberculosis_Homo sapiens_hsa051520.44170531
95Colorectal cancer_Homo sapiens_hsa052100.43823755
96Hepatitis C_Homo sapiens_hsa051600.41599848
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41384377
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.39251558
99Non-small cell lung cancer_Homo sapiens_hsa052230.38392529
100mRNA surveillance pathway_Homo sapiens_hsa030150.38070203
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.36147062
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.35570752
103Prolactin signaling pathway_Homo sapiens_hsa049170.34011175
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33049866
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.32817548
106Endocytosis_Homo sapiens_hsa041440.32317857
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30779508
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29901626
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.28931835
110VEGF signaling pathway_Homo sapiens_hsa043700.27872158
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27688503
112AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.27567499
113Arachidonic acid metabolism_Homo sapiens_hsa005900.27059906
114Linoleic acid metabolism_Homo sapiens_hsa005910.25946961
115Alcoholism_Homo sapiens_hsa050340.25552424
116Regulation of autophagy_Homo sapiens_hsa041400.21010946
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.18941295
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.17628435
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.16902054
120MAPK signaling pathway_Homo sapiens_hsa040100.16491311
121Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.14795496
122Olfactory transduction_Homo sapiens_hsa047400.14665455
123Phosphatidylinositol signaling system_Homo sapiens_hsa040700.12718082
124Lysosome_Homo sapiens_hsa041420.11142024
125Phototransduction_Homo sapiens_hsa047440.10308295
126Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.08501668
127Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.07074578
128Insulin resistance_Homo sapiens_hsa049310.04455828
129Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.01570395
130Phospholipase D signaling pathway_Homo sapiens_hsa040720.00710328
131Ether lipid metabolism_Homo sapiens_hsa00565-0.0121943
132Choline metabolism in cancer_Homo sapiens_hsa05231-0.0022716

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »