

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 6.85838925 |
| 2 | substrate-independent telencephalic tangential migration (GO:0021826) | 6.85838925 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 6.28142992 |
| 4 | negative regulation of execution phase of apoptosis (GO:1900118) | 5.65890712 |
| 5 | DNA deamination (GO:0045006) | 5.02715873 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 4.85122812 |
| 7 | cardiovascular system development (GO:0072358) | 4.70214105 |
| 8 | ribonucleoprotein complex disassembly (GO:0032988) | 4.66255048 |
| 9 | negative regulation of telomere maintenance (GO:0032205) | 4.61050051 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.57094274 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.29522256 |
| 12 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 4.20681976 |
| 13 | gonadal mesoderm development (GO:0007506) | 4.05024451 |
| 14 | protein neddylation (GO:0045116) | 3.97332340 |
| 15 | proteasome assembly (GO:0043248) | 3.95993066 |
| 16 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 3.94480848 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.93769386 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 3.93769386 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.76497040 |
| 20 | protein-cofactor linkage (GO:0018065) | 3.68305093 |
| 21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.64641994 |
| 22 | piRNA metabolic process (GO:0034587) | 3.62488300 |
| 23 | ketone body metabolic process (GO:1902224) | 3.59822152 |
| 24 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.58101616 |
| 25 | ribosomal small subunit biogenesis (GO:0042274) | 3.57538682 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55927201 |
| 27 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.54267564 |
| 28 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.54267564 |
| 29 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.53516421 |
| 30 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.49303067 |
| 31 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.49303067 |
| 32 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.49303067 |
| 33 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.49057526 |
| 34 | rRNA methylation (GO:0031167) | 3.44294565 |
| 35 | rRNA modification (GO:0000154) | 3.42445308 |
| 36 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.41734404 |
| 37 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.39019596 |
| 38 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.37459825 |
| 39 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.37459825 |
| 40 | mannosylation (GO:0097502) | 3.33640083 |
| 41 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.32778517 |
| 42 | positive regulation of translational initiation (GO:0045948) | 3.26505752 |
| 43 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.25775406 |
| 44 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.24182071 |
| 45 | viral transcription (GO:0019083) | 3.22264297 |
| 46 | platelet dense granule organization (GO:0060155) | 3.22108679 |
| 47 | kinetochore assembly (GO:0051382) | 3.21280879 |
| 48 | translational termination (GO:0006415) | 3.19106890 |
| 49 | regulation of cilium movement (GO:0003352) | 3.18641214 |
| 50 | mitotic metaphase plate congression (GO:0007080) | 3.17880202 |
| 51 | protein localization to chromosome (GO:0034502) | 3.15093297 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.14891578 |
| 53 | cotranslational protein targeting to membrane (GO:0006613) | 3.12785029 |
| 54 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.12478000 |
| 55 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.11509249 |
| 56 | kinetochore organization (GO:0051383) | 3.07898850 |
| 57 | dopamine transport (GO:0015872) | 3.06578128 |
| 58 | positive regulation of mitochondrial fission (GO:0090141) | 3.04466032 |
| 59 | spliceosomal complex assembly (GO:0000245) | 3.04404464 |
| 60 | anterograde synaptic vesicle transport (GO:0048490) | 3.04257482 |
| 61 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.03909465 |
| 62 | transmission of nerve impulse (GO:0019226) | 3.02608438 |
| 63 | myoblast migration (GO:0051451) | 3.01565795 |
| 64 | protein targeting to ER (GO:0045047) | 3.01334641 |
| 65 | ventricular cardiac muscle cell development (GO:0055015) | 3.00258970 |
| 66 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.98182875 |
| 67 | tongue development (GO:0043586) | 2.96191361 |
| 68 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.94782284 |
| 69 | auditory receptor cell differentiation (GO:0042491) | 2.94140540 |
| 70 | translational initiation (GO:0006413) | 2.93412888 |
| 71 | translational elongation (GO:0006414) | 2.93308430 |
| 72 | protein complex biogenesis (GO:0070271) | 2.91961102 |
| 73 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.91098771 |
| 74 | microtubule severing (GO:0051013) | 2.88799326 |
| 75 | negative regulation of cell cycle arrest (GO:0071157) | 2.86149677 |
| 76 | respiratory electron transport chain (GO:0022904) | 2.85949461 |
| 77 | regulation of execution phase of apoptosis (GO:1900117) | 2.85862386 |
| 78 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.85722460 |
| 79 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.85467679 |
| 80 | cellular ketone body metabolic process (GO:0046950) | 2.84695722 |
| 81 | electron transport chain (GO:0022900) | 2.83002393 |
| 82 | response to pheromone (GO:0019236) | 2.82797701 |
| 83 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.82216097 |
| 84 | negative regulation of ligase activity (GO:0051352) | 2.82216097 |
| 85 | protein localization to endoplasmic reticulum (GO:0070972) | 2.80187270 |
| 86 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.80122609 |
| 87 | regulation of penile erection (GO:0060405) | 2.77946076 |
| 88 | peptidyl-histidine modification (GO:0018202) | 2.77062675 |
| 89 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.76868338 |
| 90 | DNA double-strand break processing (GO:0000729) | 2.76155348 |
| 91 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.76021888 |
| 92 | nucleotide transmembrane transport (GO:1901679) | 2.75031256 |
| 93 | translation (GO:0006412) | 2.74784419 |
| 94 | protein polyglutamylation (GO:0018095) | 2.71714039 |
| 95 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.70133476 |
| 96 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.64546752 |
| 97 | anterograde axon cargo transport (GO:0008089) | 2.61615945 |
| 98 | cellular protein complex disassembly (GO:0043624) | 2.61599118 |
| 99 | signal transduction in response to DNA damage (GO:0042770) | 2.61453823 |
| 100 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.59748582 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 7.41660646 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.74098561 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.71326971 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.45770936 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.23866948 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.14547794 |
| 7 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.90136071 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.45153401 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 3.24369563 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79116529 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.55566138 |
| 12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.51547954 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.50882618 |
| 14 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.37940827 |
| 15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.28194931 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.10626883 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.96979000 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 1.93280752 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84468813 |
| 20 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.82066177 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.80339487 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.79911649 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.76228445 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.75861741 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.63602300 |
| 26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.57923493 |
| 27 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.55948545 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.54267279 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53885877 |
| 30 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.46773615 |
| 31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.46220653 |
| 32 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.45839552 |
| 33 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.45283759 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.43293498 |
| 35 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.40490245 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.38962457 |
| 37 | GATA1_22025678_ChIP-Seq_K562_Human | 1.36279632 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35422838 |
| 39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33207037 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32303456 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31045194 |
| 42 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.27202374 |
| 43 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.24973676 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.22607631 |
| 45 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.15729066 |
| 46 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.13368515 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13365771 |
| 48 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.12519465 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12258356 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.11256022 |
| 51 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.11017718 |
| 52 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.10297198 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.07620287 |
| 54 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.06534059 |
| 55 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.05897699 |
| 56 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05486420 |
| 57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02140213 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02140213 |
| 59 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02104286 |
| 60 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01273801 |
| 61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01031767 |
| 62 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.00392854 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.99864383 |
| 64 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.99227332 |
| 65 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98776136 |
| 66 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.98539007 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.96364280 |
| 68 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.95956445 |
| 69 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.94323607 |
| 70 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94069937 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.93099507 |
| 72 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.92778912 |
| 73 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92596020 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91714650 |
| 75 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89827715 |
| 76 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.89592048 |
| 77 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.87466490 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.87073269 |
| 79 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.86546780 |
| 80 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86427479 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86201136 |
| 82 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.84588815 |
| 83 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.84053254 |
| 84 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.84032670 |
| 85 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.83557469 |
| 86 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.83509373 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.83432665 |
| 88 | * NANOG_19829295_ChIP-Seq_ESCs_Human | 0.81692702 |
| 89 | * SOX2_19829295_ChIP-Seq_ESCs_Human | 0.81692702 |
| 90 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.81038393 |
| 91 | AR_20517297_ChIP-Seq_VCAP_Human | 0.80471648 |
| 92 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.79770143 |
| 93 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.78898046 |
| 94 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.78813125 |
| 95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.78449492 |
| 96 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.77916083 |
| 97 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.77695825 |
| 98 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.77091955 |
| 99 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.76163171 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.75454685 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.68100721 |
| 2 | MP0010030_abnormal_orbit_morphology | 3.93447314 |
| 3 | MP0003136_yellow_coat_color | 3.57743400 |
| 4 | MP0009379_abnormal_foot_pigmentation | 2.94671409 |
| 5 | MP0002653_abnormal_ependyma_morphology | 2.85558551 |
| 6 | MP0002102_abnormal_ear_morphology | 2.74844045 |
| 7 | MP0000015_abnormal_ear_pigmentation | 2.70064023 |
| 8 | MP0004147_increased_porphyrin_level | 2.62712420 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 2.41633464 |
| 10 | MP0003646_muscle_fatigue | 2.38849030 |
| 11 | MP0005171_absent_coat_pigmentation | 2.38533536 |
| 12 | MP0000569_abnormal_digit_pigmentation | 2.28330613 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 2.22881511 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.18406933 |
| 15 | MP0001293_anophthalmia | 2.14655846 |
| 16 | MP0002277_abnormal_respiratory_mucosa | 2.14347670 |
| 17 | MP0005174_abnormal_tail_pigmentation | 2.10527795 |
| 18 | MP0001485_abnormal_pinna_reflex | 2.10246460 |
| 19 | MP0003693_abnormal_embryo_hatching | 2.09124467 |
| 20 | MP0000566_synostosis | 2.03955025 |
| 21 | MP0002736_abnormal_nociception_after | 2.03166211 |
| 22 | MP0002876_abnormal_thyroid_physiology | 1.95818971 |
| 23 | MP0008995_early_reproductive_senescence | 1.92292464 |
| 24 | MP0002095_abnormal_skin_pigmentation | 1.87968888 |
| 25 | MP0008058_abnormal_DNA_repair | 1.87513933 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.78698483 |
| 27 | MP0003718_maternal_effect | 1.73714991 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.71988892 |
| 29 | MP0003938_abnormal_ear_development | 1.67198358 |
| 30 | MP0004133_heterotaxia | 1.60449527 |
| 31 | MP0002163_abnormal_gland_morphology | 1.58756261 |
| 32 | MP0002938_white_spotting | 1.57400144 |
| 33 | MP0008789_abnormal_olfactory_epithelium | 1.56458495 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.54300758 |
| 35 | MP0003221_abnormal_cardiomyocyte_apopto | 1.54103798 |
| 36 | MP0000049_abnormal_middle_ear | 1.51878788 |
| 37 | MP0003878_abnormal_ear_physiology | 1.43208105 |
| 38 | MP0005377_hearing/vestibular/ear_phenot | 1.43208105 |
| 39 | MP0005408_hypopigmentation | 1.37841848 |
| 40 | MP0004142_abnormal_muscle_tone | 1.37434275 |
| 41 | MP0001986_abnormal_taste_sensitivity | 1.34792379 |
| 42 | MP0002233_abnormal_nose_morphology | 1.34569585 |
| 43 | MP0001984_abnormal_olfaction | 1.32908068 |
| 44 | MP0005084_abnormal_gallbladder_morpholo | 1.29532630 |
| 45 | MP0005075_abnormal_melanosome_morpholog | 1.28734517 |
| 46 | MP0002272_abnormal_nervous_system | 1.27821533 |
| 47 | MP0010094_abnormal_chromosome_stability | 1.26921059 |
| 48 | MP0003806_abnormal_nucleotide_metabolis | 1.26023664 |
| 49 | MP0002127_abnormal_cardiovascular_syste | 1.25293499 |
| 50 | MP0004145_abnormal_muscle_electrophysio | 1.14461267 |
| 51 | MP0000631_abnormal_neuroendocrine_gland | 1.13045630 |
| 52 | MP0008932_abnormal_embryonic_tissue | 1.11276172 |
| 53 | MP0000778_abnormal_nervous_system | 1.09982685 |
| 54 | MP0009046_muscle_twitch | 1.09615515 |
| 55 | MP0001286_abnormal_eye_development | 1.09535467 |
| 56 | MP0003122_maternal_imprinting | 1.07189278 |
| 57 | MP0000026_abnormal_inner_ear | 1.03845718 |
| 58 | MP0001348_abnormal_lacrimal_gland | 1.03350778 |
| 59 | MP0005394_taste/olfaction_phenotype | 1.02926514 |
| 60 | MP0005499_abnormal_olfactory_system | 1.02926514 |
| 61 | MP0001324_abnormal_eye_pigmentation | 1.01500010 |
| 62 | MP0005379_endocrine/exocrine_gland_phen | 1.00861665 |
| 63 | MP0001486_abnormal_startle_reflex | 0.98837161 |
| 64 | MP0004885_abnormal_endolymph | 0.97297471 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 0.95491766 |
| 66 | MP0003077_abnormal_cell_cycle | 0.93945492 |
| 67 | MP0008877_abnormal_DNA_methylation | 0.93659665 |
| 68 | MP0003186_abnormal_redox_activity | 0.93072295 |
| 69 | MP0006036_abnormal_mitochondrial_physio | 0.92770024 |
| 70 | MP0002282_abnormal_trachea_morphology | 0.91507764 |
| 71 | MP0002177_abnormal_outer_ear | 0.91322159 |
| 72 | MP0003880_abnormal_central_pattern | 0.90979223 |
| 73 | MP0004957_abnormal_blastocyst_morpholog | 0.90493732 |
| 74 | MP0001905_abnormal_dopamine_level | 0.90039721 |
| 75 | MP0002928_abnormal_bile_duct | 0.86643094 |
| 76 | MP0003567_abnormal_fetal_cardiomyocyte | 0.84182381 |
| 77 | MP0000639_abnormal_adrenal_gland | 0.83858902 |
| 78 | MP0005395_other_phenotype | 0.80754256 |
| 79 | MP0003385_abnormal_body_wall | 0.80667659 |
| 80 | MP0002735_abnormal_chemical_nociception | 0.80067044 |
| 81 | MP0002210_abnormal_sex_determination | 0.80046441 |
| 82 | MP0003755_abnormal_palate_morphology | 0.76006797 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.73356938 |
| 84 | MP0003183_abnormal_peptide_metabolism | 0.69548390 |
| 85 | MP0005195_abnormal_posterior_eye | 0.69047824 |
| 86 | MP0008872_abnormal_physiological_respon | 0.67963676 |
| 87 | MP0002752_abnormal_somatic_nervous | 0.67760923 |
| 88 | MP0001529_abnormal_vocalization | 0.66385617 |
| 89 | MP0005266_abnormal_metabolism | 0.65129216 |
| 90 | MP0003937_abnormal_limbs/digits/tail_de | 0.64854416 |
| 91 | MP0005167_abnormal_blood-brain_barrier | 0.64476940 |
| 92 | MP0009053_abnormal_anal_canal | 0.63977860 |
| 93 | MP0003786_premature_aging | 0.63095547 |
| 94 | MP0001963_abnormal_hearing_physiology | 0.62619349 |
| 95 | MP0002822_catalepsy | 0.62016362 |
| 96 | MP0000685_abnormal_immune_system | 0.61109119 |
| 97 | MP0001929_abnormal_gametogenesis | 0.60754755 |
| 98 | MP0008775_abnormal_heart_ventricle | 0.60286223 |
| 99 | MP0003195_calcinosis | 0.60127868 |
| 100 | MP0004811_abnormal_neuron_physiology | 0.58603346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Rib fusion (HP:0000902) | 4.82407315 |
| 2 | Reticulocytopenia (HP:0001896) | 4.48235320 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.85738177 |
| 4 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.82145669 |
| 5 | Septo-optic dysplasia (HP:0100842) | 3.79374791 |
| 6 | Tubulointerstitial nephritis (HP:0001970) | 3.71721293 |
| 7 | Stenosis of the external auditory canal (HP:0000402) | 3.68239982 |
| 8 | Absent thumb (HP:0009777) | 3.52848004 |
| 9 | Abnormality of the labia minora (HP:0012880) | 3.36938033 |
| 10 | Colon cancer (HP:0003003) | 3.24727353 |
| 11 | Hip dysplasia (HP:0001385) | 3.23064328 |
| 12 | Supernumerary spleens (HP:0009799) | 3.17459053 |
| 13 | Increased CSF lactate (HP:0002490) | 3.13172785 |
| 14 | Congenital stationary night blindness (HP:0007642) | 3.05144195 |
| 15 | Cerebral hypomyelination (HP:0006808) | 3.04378653 |
| 16 | Flat capital femoral epiphysis (HP:0003370) | 2.98405288 |
| 17 | Acute necrotizing encephalopathy (HP:0006965) | 2.94438449 |
| 18 | Anterior segment dysgenesis (HP:0007700) | 2.90764473 |
| 19 | Absent septum pellucidum (HP:0001331) | 2.83904996 |
| 20 | Abnormal number of erythroid precursors (HP:0012131) | 2.78884149 |
| 21 | Mitochondrial inheritance (HP:0001427) | 2.78094527 |
| 22 | Tubular atrophy (HP:0000092) | 2.73920070 |
| 23 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.64268196 |
| 24 | Abnormality of glycolysis (HP:0004366) | 2.64162488 |
| 25 | Maternal diabetes (HP:0009800) | 2.61868738 |
| 26 | Molar tooth sign on MRI (HP:0002419) | 2.60495105 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.60495105 |
| 28 | Optic nerve hypoplasia (HP:0000609) | 2.56764191 |
| 29 | Hepatic necrosis (HP:0002605) | 2.47628849 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.46459615 |
| 31 | Myokymia (HP:0002411) | 2.41446068 |
| 32 | Pancreatic cysts (HP:0001737) | 2.40048466 |
| 33 | Nephronophthisis (HP:0000090) | 2.39105922 |
| 34 | B lymphocytopenia (HP:0010976) | 2.38597297 |
| 35 | Neoplasm of the adrenal cortex (HP:0100641) | 2.37788082 |
| 36 | Failure to thrive in infancy (HP:0001531) | 2.36286172 |
| 37 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.34356937 |
| 38 | Progressive macrocephaly (HP:0004481) | 2.34177352 |
| 39 | Abnormality of the septum pellucidum (HP:0007375) | 2.33737280 |
| 40 | Oligodactyly (HP:0012165) | 2.32561046 |
| 41 | Synostosis involving the elbow (HP:0003938) | 2.31672389 |
| 42 | Humeroradial synostosis (HP:0003041) | 2.31672389 |
| 43 | Small hand (HP:0200055) | 2.31634688 |
| 44 | Concave nail (HP:0001598) | 2.29868273 |
| 45 | Increased serum lactate (HP:0002151) | 2.28575123 |
| 46 | Hepatocellular necrosis (HP:0001404) | 2.26476340 |
| 47 | Sclerocornea (HP:0000647) | 2.25837426 |
| 48 | Acute encephalopathy (HP:0006846) | 2.25429429 |
| 49 | Thyroid-stimulating hormone excess (HP:0002925) | 2.22511960 |
| 50 | Focal motor seizures (HP:0011153) | 2.20790227 |
| 51 | Retinal dysplasia (HP:0007973) | 2.18615651 |
| 52 | Chromsome breakage (HP:0040012) | 2.15336309 |
| 53 | Hypoplasia of the ulna (HP:0003022) | 2.15228569 |
| 54 | Hypoplasia of the fovea (HP:0007750) | 2.14349122 |
| 55 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.14349122 |
| 56 | 3-Methylglutaconic aciduria (HP:0003535) | 2.13705528 |
| 57 | Gonadotropin excess (HP:0000837) | 2.11615648 |
| 58 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.09821684 |
| 59 | Abnormality of the diencephalon (HP:0010662) | 2.08467067 |
| 60 | IgG deficiency (HP:0004315) | 2.08001575 |
| 61 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.07069985 |
| 62 | Missing ribs (HP:0000921) | 2.06033251 |
| 63 | Abnormality of B cell number (HP:0010975) | 2.05469037 |
| 64 | Poor head control (HP:0002421) | 2.05358712 |
| 65 | Adrenal hypoplasia (HP:0000835) | 2.03765745 |
| 66 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.03639171 |
| 67 | Abnormality of the renal collecting system (HP:0004742) | 2.01286005 |
| 68 | Premature ovarian failure (HP:0008209) | 2.00032194 |
| 69 | Carpal bone hypoplasia (HP:0001498) | 1.99775958 |
| 70 | Increased IgM level (HP:0003496) | 1.99691630 |
| 71 | CNS hypomyelination (HP:0003429) | 1.97131340 |
| 72 | Pallor (HP:0000980) | 1.96230798 |
| 73 | Abnormality of the renal medulla (HP:0100957) | 1.94007737 |
| 74 | Macrocytic anemia (HP:0001972) | 1.93854812 |
| 75 | Partial duplication of thumb phalanx (HP:0009944) | 1.92621064 |
| 76 | Rhabdomyosarcoma (HP:0002859) | 1.91440129 |
| 77 | Abnormal lung lobation (HP:0002101) | 1.90379949 |
| 78 | Generalized aminoaciduria (HP:0002909) | 1.87852918 |
| 79 | Esophageal atresia (HP:0002032) | 1.87163878 |
| 80 | Increased hepatocellular lipid droplets (HP:0006565) | 1.86572446 |
| 81 | Duplicated collecting system (HP:0000081) | 1.85889623 |
| 82 | Ectopic kidney (HP:0000086) | 1.85111697 |
| 83 | Overriding aorta (HP:0002623) | 1.80272290 |
| 84 | Growth hormone deficiency (HP:0000824) | 1.79880218 |
| 85 | Lipid accumulation in hepatocytes (HP:0006561) | 1.79754369 |
| 86 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.79180854 |
| 87 | Lissencephaly (HP:0001339) | 1.79109558 |
| 88 | Polyphagia (HP:0002591) | 1.78078334 |
| 89 | Respiratory difficulties (HP:0002880) | 1.77958680 |
| 90 | Increased serum pyruvate (HP:0003542) | 1.76494783 |
| 91 | Hemivertebrae (HP:0002937) | 1.76293351 |
| 92 | Oligodactyly (hands) (HP:0001180) | 1.75028605 |
| 93 | Iris hypopigmentation (HP:0007730) | 1.73036474 |
| 94 | CNS demyelination (HP:0007305) | 1.72610182 |
| 95 | Type II lissencephaly (HP:0007260) | 1.71760204 |
| 96 | Medial flaring of the eyebrow (HP:0010747) | 1.71471522 |
| 97 | Asplenia (HP:0001746) | 1.71255908 |
| 98 | Forearm undergrowth (HP:0009821) | 1.68116101 |
| 99 | Abnormality of the fovea (HP:0000493) | 1.67864300 |
| 100 | Atonic seizures (HP:0010819) | 1.67638458 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.41581336 |
| 2 | MAP3K9 | 3.67159255 |
| 3 | CCNB1 | 3.63742580 |
| 4 | MAP3K12 | 3.38681993 |
| 5 | MAP4K2 | 3.31406919 |
| 6 | STK39 | 3.14285977 |
| 7 | VRK2 | 3.06318664 |
| 8 | WNK4 | 2.65468436 |
| 9 | CASK | 2.18237484 |
| 10 | PDK2 | 2.16228067 |
| 11 | INSRR | 2.01984535 |
| 12 | STK16 | 1.69253656 |
| 13 | LRRK2 | 1.66930602 |
| 14 | EIF2AK1 | 1.54540642 |
| 15 | NEK1 | 1.46445407 |
| 16 | MAP3K13 | 1.46038801 |
| 17 | PAK3 | 1.43565913 |
| 18 | TAF1 | 1.40752231 |
| 19 | TSSK6 | 1.38696055 |
| 20 | SRPK1 | 1.34939013 |
| 21 | EIF2AK3 | 1.29686392 |
| 22 | BRAF | 1.25554686 |
| 23 | MST4 | 1.23129849 |
| 24 | PLK2 | 1.22741510 |
| 25 | LIMK1 | 1.19243018 |
| 26 | PLK3 | 1.18752114 |
| 27 | DAPK3 | 1.18592576 |
| 28 | MKNK1 | 1.18249396 |
| 29 | KSR1 | 1.14958455 |
| 30 | KDR | 1.14101408 |
| 31 | TRIM28 | 1.12037108 |
| 32 | NUAK1 | 1.09115273 |
| 33 | GRK1 | 1.07149617 |
| 34 | BRSK2 | 1.04146184 |
| 35 | WEE1 | 1.03532181 |
| 36 | PLK4 | 1.02525260 |
| 37 | ATR | 1.01353299 |
| 38 | MAPK13 | 1.00511599 |
| 39 | TESK2 | 0.98633562 |
| 40 | ARAF | 0.94991780 |
| 41 | PINK1 | 0.93999294 |
| 42 | VRK1 | 0.91549168 |
| 43 | MKNK2 | 0.89827542 |
| 44 | MAPKAPK5 | 0.87190027 |
| 45 | OXSR1 | 0.86847587 |
| 46 | KSR2 | 0.86631337 |
| 47 | TEC | 0.86360352 |
| 48 | EIF2AK2 | 0.82652835 |
| 49 | PLK1 | 0.81449305 |
| 50 | ADRBK2 | 0.79786989 |
| 51 | TGFBR2 | 0.79666381 |
| 52 | NEK2 | 0.79202780 |
| 53 | STK38L | 0.78246442 |
| 54 | FRK | 0.76875090 |
| 55 | DAPK1 | 0.76693065 |
| 56 | PAK6 | 0.75804496 |
| 57 | DYRK2 | 0.74858359 |
| 58 | BRSK1 | 0.74788471 |
| 59 | MARK3 | 0.72013163 |
| 60 | WNK3 | 0.67658850 |
| 61 | CSNK1E | 0.66682759 |
| 62 | TTK | 0.66424691 |
| 63 | TLK1 | 0.65979038 |
| 64 | AURKB | 0.64918267 |
| 65 | PAK2 | 0.63706045 |
| 66 | TIE1 | 0.63364005 |
| 67 | CDK8 | 0.63044550 |
| 68 | AKT3 | 0.62444820 |
| 69 | PRKCG | 0.60746322 |
| 70 | CSNK1G3 | 0.59961669 |
| 71 | CSNK1G1 | 0.58336698 |
| 72 | RPS6KA4 | 0.56849560 |
| 73 | FGFR2 | 0.55073303 |
| 74 | PIM1 | 0.54316759 |
| 75 | CSNK1G2 | 0.53248230 |
| 76 | MAP3K5 | 0.52894758 |
| 77 | CHEK2 | 0.51296366 |
| 78 | CSNK1A1L | 0.50739642 |
| 79 | BCKDK | 0.50083177 |
| 80 | CDK7 | 0.49729666 |
| 81 | CDK18 | 0.48528928 |
| 82 | NEK9 | 0.48299259 |
| 83 | PIK3CA | 0.47937657 |
| 84 | PRKCQ | 0.47602620 |
| 85 | PRKAA2 | 0.47471071 |
| 86 | CHEK1 | 0.45126497 |
| 87 | PKN1 | 0.44246505 |
| 88 | CDK15 | 0.44156263 |
| 89 | CSNK2A1 | 0.44068243 |
| 90 | GRK5 | 0.43374048 |
| 91 | ABL2 | 0.43126284 |
| 92 | CSNK2A2 | 0.42815303 |
| 93 | RAF1 | 0.41924293 |
| 94 | ZAK | 0.41688133 |
| 95 | CDK14 | 0.39537661 |
| 96 | CDK11A | 0.39138880 |
| 97 | ATM | 0.39069941 |
| 98 | CLK1 | 0.38936893 |
| 99 | DYRK1A | 0.38431115 |
| 100 | STK3 | 0.37985060 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.11618550 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.93899191 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.84689276 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.51847943 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.26710933 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 3.08501028 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.87847814 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.79151710 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48263724 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.28891850 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.07100902 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.05395099 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.04124950 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.91280771 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.86533869 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.83600341 |
| 17 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.74154338 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.71900307 |
| 19 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.64888387 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.63519872 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.63176954 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.57357262 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.47618589 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44488222 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.32861646 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.29210203 |
| 27 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.28063357 |
| 28 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.19308206 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.17609138 |
| 30 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.15100081 |
| 31 | Cell cycle_Homo sapiens_hsa04110 | 1.14331482 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.13029548 |
| 33 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12410283 |
| 34 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.10303235 |
| 35 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.05937556 |
| 36 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.05928712 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.03505271 |
| 38 | Mismatch repair_Homo sapiens_hsa03430 | 0.97512065 |
| 39 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.96799952 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.95607074 |
| 41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.92738436 |
| 42 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.91744729 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.90411413 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.87456995 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.86062965 |
| 46 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.86056882 |
| 47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.86048079 |
| 48 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.77749974 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77302722 |
| 50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.75779123 |
| 51 | Purine metabolism_Homo sapiens_hsa00230 | 0.73751167 |
| 52 | Taste transduction_Homo sapiens_hsa04742 | 0.73199288 |
| 53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.71749999 |
| 54 | DNA replication_Homo sapiens_hsa03030 | 0.71115567 |
| 55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70932058 |
| 56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.69345689 |
| 57 | Base excision repair_Homo sapiens_hsa03410 | 0.68917318 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67509700 |
| 59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.66380844 |
| 60 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66310380 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64944345 |
| 62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.59616690 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58490348 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58430341 |
| 65 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.58189420 |
| 66 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.54759351 |
| 67 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53756948 |
| 68 | Nicotine addiction_Homo sapiens_hsa05033 | 0.48477385 |
| 69 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.46774039 |
| 70 | Asthma_Homo sapiens_hsa05310 | 0.46176012 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45993641 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.45975825 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45781232 |
| 74 | Peroxisome_Homo sapiens_hsa04146 | 0.44480638 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44432578 |
| 76 | Phototransduction_Homo sapiens_hsa04744 | 0.43814047 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43302387 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42031400 |
| 79 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.40184543 |
| 80 | Alcoholism_Homo sapiens_hsa05034 | 0.35546034 |
| 81 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.30418039 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.27556162 |
| 83 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.25584827 |
| 84 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.24460273 |
| 85 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.23688985 |
| 86 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.23653045 |
| 87 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.23090796 |
| 88 | Allograft rejection_Homo sapiens_hsa05330 | 0.21658523 |
| 89 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.20927922 |
| 90 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.19819220 |
| 91 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.19462831 |
| 92 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.19393314 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.17898831 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.15075030 |
| 95 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.14919614 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.14815012 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.14552212 |
| 98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.14039628 |
| 99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.12408168 |
| 100 | Bladder cancer_Homo sapiens_hsa05219 | 0.12374565 |

