PUS7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.60486109
2DNA replication initiation (GO:0006270)4.53311143
3maturation of SSU-rRNA (GO:0030490)4.51505522
4telomere maintenance via semi-conservative replication (GO:0032201)4.44098940
5DNA strand elongation (GO:0022616)4.43977937
6DNA unwinding involved in DNA replication (GO:0006268)4.32905705
7ribosomal small subunit biogenesis (GO:0042274)4.27937530
8ribosomal small subunit assembly (GO:0000028)4.02425778
9mitotic sister chromatid segregation (GO:0000070)3.97294915
10ribonucleoprotein complex biogenesis (GO:0022613)3.95983199
11DNA deamination (GO:0045006)3.93435333
12nucleobase biosynthetic process (GO:0046112)3.92819583
13ribosomal large subunit biogenesis (GO:0042273)3.92390030
14ribosome biogenesis (GO:0042254)3.89946895
15telomere maintenance via recombination (GO:0000722)3.88388600
16ribosome assembly (GO:0042255)3.84099753
17mitotic sister chromatid cohesion (GO:0007064)3.82782608
18sister chromatid segregation (GO:0000819)3.78750105
19regulation of centriole replication (GO:0046599)3.76625935
20viral transcription (GO:0019083)3.75501341
21CENP-A containing nucleosome assembly (GO:0034080)3.75485823
22mitotic chromosome condensation (GO:0007076)3.74466683
23rRNA processing (GO:0006364)3.72729906
24translational termination (GO:0006415)3.72545359
25IMP biosynthetic process (GO:0006188)3.71442942
26non-recombinational repair (GO:0000726)3.70693520
27double-strand break repair via nonhomologous end joining (GO:0006303)3.70693520
28chromatin remodeling at centromere (GO:0031055)3.69804697
29mitochondrial RNA metabolic process (GO:0000959)3.67621818
30formation of translation preinitiation complex (GO:0001731)3.65711092
31mitotic recombination (GO:0006312)3.65641956
32telomere maintenance via telomere lengthening (GO:0010833)3.64854076
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.61622105
34protein complex localization (GO:0031503)3.61472515
35L-serine metabolic process (GO:0006563)3.61432170
36DNA replication checkpoint (GO:0000076)3.61074192
37rRNA metabolic process (GO:0016072)3.59508510
38nuclear pore organization (GO:0006999)3.58512848
39protein localization to kinetochore (GO:0034501)3.56961939
40DNA ligation (GO:0006266)3.55571677
41cellular protein complex localization (GO:0034629)3.53004269
42purine nucleobase biosynthetic process (GO:0009113)3.49583686
43pteridine-containing compound biosynthetic process (GO:0042559)3.46347372
44DNA topological change (GO:0006265)3.46025983
45nuclear pore complex assembly (GO:0051292)3.46013554
46mitotic metaphase plate congression (GO:0007080)3.43573016
47kinetochore organization (GO:0051383)3.42825587
48spliceosomal snRNP assembly (GO:0000387)3.41085502
49folic acid-containing compound biosynthetic process (GO:0009396)3.40121783
50regulation of translational fidelity (GO:0006450)3.39939346
51translational initiation (GO:0006413)3.38492671
52mitotic nuclear envelope disassembly (GO:0007077)3.36165329
53kinetochore assembly (GO:0051382)3.29865753
54spindle checkpoint (GO:0031577)3.29222059
55translational elongation (GO:0006414)3.27959401
56transcription-coupled nucleotide-excision repair (GO:0006283)3.27796985
57DNA replication-independent nucleosome organization (GO:0034724)3.27175952
58DNA replication-independent nucleosome assembly (GO:0006336)3.27175952
59IMP metabolic process (GO:0046040)3.25857211
60nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.24232949
61regulation of centrosome cycle (GO:0046605)3.22803478
62rRNA modification (GO:0000154)3.21347489
63negative regulation of chromosome segregation (GO:0051985)3.21189481
64mitotic spindle checkpoint (GO:0071174)3.20015523
65DNA replication-dependent nucleosome organization (GO:0034723)3.19793306
66DNA replication-dependent nucleosome assembly (GO:0006335)3.19793306
67* pseudouridine synthesis (GO:0001522)3.19271831
68ATP-dependent chromatin remodeling (GO:0043044)3.18653667
69tRNA aminoacylation for protein translation (GO:0006418)3.17963836
70DNA double-strand break processing (GO:0000729)3.17946724
71establishment of integrated proviral latency (GO:0075713)3.16261163
72tRNA aminoacylation (GO:0043039)3.16233144
73amino acid activation (GO:0043038)3.16233144
74establishment of chromosome localization (GO:0051303)3.15879526
75negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15608700
76negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.15608700
77negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15608700
78negative regulation of mitotic sister chromatid separation (GO:2000816)3.15608700
79negative regulation of sister chromatid segregation (GO:0033046)3.15608700
80tRNA methylation (GO:0030488)3.15038782
81positive regulation of chromosome segregation (GO:0051984)3.14345343
82SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.14289719
83tetrahydrofolate metabolic process (GO:0046653)3.13035264
84establishment of viral latency (GO:0019043)3.12762743
85regulation of chromosome segregation (GO:0051983)3.12749699
86regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.11062567
87transcription from mitochondrial promoter (GO:0006390)3.09991326
88termination of RNA polymerase III transcription (GO:0006386)3.09928484
89transcription elongation from RNA polymerase III promoter (GO:0006385)3.09928484
90cotranslational protein targeting to membrane (GO:0006613)3.09477291
91metaphase plate congression (GO:0051310)3.08675499
92protein targeting to ER (GO:0045047)3.06909423
93nuclear envelope disassembly (GO:0051081)3.05112808
94membrane disassembly (GO:0030397)3.05112808
95chromatin assembly or disassembly (GO:0006333)3.03403666
96protein localization to chromosome, centromeric region (GO:0071459)3.03102011
97regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.02314331
98regulation of mitotic metaphase/anaphase transition (GO:0030071)3.02314331
99viral mRNA export from host cell nucleus (GO:0046784)3.01702847
100regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.99741775
101regulation of mitotic spindle checkpoint (GO:1903504)2.99741775
102DNA duplex unwinding (GO:0032508)2.97379649
103regulation of nuclear cell cycle DNA replication (GO:0033262)2.96941378
104* ncRNA processing (GO:0034470)2.96462322
105DNA geometric change (GO:0032392)2.95711081
106cellular component biogenesis (GO:0044085)2.95698230
107mitotic spindle assembly checkpoint (GO:0007094)2.95594632
108transcription elongation from RNA polymerase I promoter (GO:0006362)2.95553571
109maturation of 5.8S rRNA (GO:0000460)2.94911738
110negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.94165692
111DNA conformation change (GO:0071103)2.94043331
112cellular protein complex disassembly (GO:0043624)2.93710723
113mismatch repair (GO:0006298)2.93652884
114termination of RNA polymerase I transcription (GO:0006363)2.93231229
115proteasome assembly (GO:0043248)2.92836067
116spindle assembly checkpoint (GO:0071173)2.92770320
117regulation of sister chromatid segregation (GO:0033045)2.92734416
118regulation of mitotic sister chromatid separation (GO:0010965)2.92734416
119regulation of mitotic sister chromatid segregation (GO:0033047)2.92734416
120histone exchange (GO:0043486)2.91961616
121somatic hypermutation of immunoglobulin genes (GO:0016446)2.91622165
122somatic diversification of immune receptors via somatic mutation (GO:0002566)2.91622165
123termination of RNA polymerase II transcription (GO:0006369)2.91215866
124establishment of protein localization to endoplasmic reticulum (GO:0072599)2.91183524
125maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.91154664
126spliceosomal complex assembly (GO:0000245)2.91145313
127DNA-templated transcription, termination (GO:0006353)2.91029107
128negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.89265846
129protein localization to endoplasmic reticulum (GO:0070972)2.88438710
130viral life cycle (GO:0019058)2.87007092
131regulation of spindle organization (GO:0090224)2.86417013
132regulation of helicase activity (GO:0051095)2.86290464
133regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.85962087
134regulation of double-strand break repair via homologous recombination (GO:0010569)2.85021258
135exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.84599610
136* ncRNA metabolic process (GO:0034660)2.84167500
137RNA splicing, via transesterification reactions (GO:0000375)2.83121798
138meiotic chromosome segregation (GO:0045132)2.82233966
139telomere maintenance (GO:0000723)2.81578223
140regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.81135866
141negative regulation of RNA splicing (GO:0033119)2.81114343
142telomere organization (GO:0032200)2.80631171
143negative regulation of mRNA processing (GO:0050686)2.80513302
144RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.80101921
145mRNA splicing, via spliceosome (GO:0000398)2.80101921
146nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.79848016
147nuclear-transcribed mRNA catabolic process (GO:0000956)2.79449466
148pore complex assembly (GO:0046931)2.79414898

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.34375590
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.82920290
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.95548564
4MYC_19079543_ChIP-ChIP_MESCs_Mouse3.31167740
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.28355840
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.23669012
7FOXM1_23109430_ChIP-Seq_U2OS_Human3.16795789
8MYC_19030024_ChIP-ChIP_MESCs_Mouse3.12658950
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.09046334
10EST1_17652178_ChIP-ChIP_JURKAT_Human3.07137307
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.00716761
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.93183022
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.91071637
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.85114871
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.56829634
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.56079893
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.50466293
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.44360309
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.39758311
20VDR_23849224_ChIP-Seq_CD4+_Human2.35930612
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.32988377
22XRN2_22483619_ChIP-Seq_HELA_Human2.30448599
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.21711635
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.16343516
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08643123
26FOXP3_21729870_ChIP-Seq_TREG_Human2.06848966
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.06202912
28E2F1_21310950_ChIP-Seq_MCF-7_Human2.06135922
29AR_21909140_ChIP-Seq_LNCAP_Human2.04833920
30KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.03221650
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98144167
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.97584046
33CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.97196591
34DCP1A_22483619_ChIP-Seq_HELA_Human1.95166851
35ELK1_19687146_ChIP-ChIP_HELA_Human1.94738891
36TTF2_22483619_ChIP-Seq_HELA_Human1.93967034
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.90581830
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.82984933
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.76889936
40YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76697270
41RBPJ_22232070_ChIP-Seq_NCS_Mouse1.73851319
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.73406192
43GABP_19822575_ChIP-Seq_HepG2_Human1.72499014
44MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70547464
45NOTCH1_21737748_ChIP-Seq_TLL_Human1.63700272
46PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.58732499
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58097219
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55745932
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55180517
50KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.52931339
51KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.52931339
52KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.52931339
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49745952
54SRF_21415370_ChIP-Seq_HL-1_Mouse1.47532173
55* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46102481
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46093509
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.44146396
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.43279061
59KDM5A_27292631_Chip-Seq_BREAST_Human1.42849435
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42286870
61SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39836190
62SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.37082531
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34201340
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33576525
65CIITA_25753668_ChIP-Seq_RAJI_Human1.30919265
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29238698
67CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.27434534
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25708514
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23189961
70MYC_18940864_ChIP-ChIP_HL60_Human1.21701145
71ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20343079
72HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18792290
73SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.18329208
74FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17939277
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11687150
76EGR1_19374776_ChIP-ChIP_THP-1_Human1.09771320
77ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09633518
78DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.09050700
79CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06539576
80SALL1_21062744_ChIP-ChIP_HESCs_Human1.05107374
81DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03711483
82CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03115582
83STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00941525
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97437713
85POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97192628
86* MYC_22102868_ChIP-Seq_BL_Human0.96683908
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95167371
88ZNF263_19887448_ChIP-Seq_K562_Human0.94022893
89FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93136715
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92694637
91EWS_26573619_Chip-Seq_HEK293_Human0.92184234
92POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91766496
93ELK1_22589737_ChIP-Seq_MCF10A_Human0.89957520
94* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.89620096
95SOX2_16153702_ChIP-ChIP_HESCs_Human0.88004213
96TFEB_21752829_ChIP-Seq_HELA_Human0.86621233
97NANOG_16153702_ChIP-ChIP_HESCs_Human0.85925439
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85896852
99ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.85879513
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.85474959
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84162202
102SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83737823
103NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.83517351
104CHD1_26751641_Chip-Seq_LNCaP_Human0.83402419
105TCF3_18692474_ChIP-Seq_MESCs_Mouse0.83252075
106IRF1_19129219_ChIP-ChIP_H3396_Human0.83226313
107NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81565501
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.81201803
109TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.81139838
110CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.80865799
111PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.76448417
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73695424
113CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71551565
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.71110037
115SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.70378598
116FUS_26573619_Chip-Seq_HEK293_Human0.69229850
117TBX5_21415370_ChIP-Seq_HL-1_Mouse0.68376050

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.97470518
2MP0003693_abnormal_embryo_hatching4.20118927
3MP0010094_abnormal_chromosome_stability4.18879300
4MP0003111_abnormal_nucleus_morphology3.84749673
5MP0004957_abnormal_blastocyst_morpholog3.58094947
6MP0003077_abnormal_cell_cycle3.42085741
7MP0008058_abnormal_DNA_repair3.38446487
8MP0008932_abnormal_embryonic_tissue2.78462733
9MP0009697_abnormal_copulation2.69924043
10MP0002396_abnormal_hematopoietic_system2.53170057
11MP0003136_yellow_coat_color2.32193345
12MP0008007_abnormal_cellular_replicative2.31712909
13MP0006292_abnormal_olfactory_placode2.11002585
14MP0003786_premature_aging2.06267394
15MP0008877_abnormal_DNA_methylation1.89229021
16MP0000490_abnormal_crypts_of1.85534253
17MP0000350_abnormal_cell_proliferation1.85234259
18MP0001730_embryonic_growth_arrest1.77444841
19MP0005075_abnormal_melanosome_morpholog1.74409170
20MP0003123_paternal_imprinting1.71962210
21MP0002938_white_spotting1.69126047
22MP0000566_synostosis1.65972126
23MP0009672_abnormal_birth_weight1.56322837
24MP0001293_anophthalmia1.56222479
25MP0004233_abnormal_muscle_weight1.48467806
26MP0003890_abnormal_embryonic-extraembry1.46348385
27MP0003567_abnormal_fetal_cardiomyocyte1.46068025
28MP0002085_abnormal_embryonic_tissue1.45900804
29MP0001672_abnormal_embryogenesis/_devel1.44517192
30MP0005380_embryogenesis_phenotype1.44517192
31MP0010030_abnormal_orbit_morphology1.41493832
32MP0005171_absent_coat_pigmentation1.40061073
33MP0004185_abnormal_adipocyte_glucose1.37998352
34MP0001697_abnormal_embryo_size1.36913185
35MP0001661_extended_life_span1.36625602
36MP0003718_maternal_effect1.36592508
37MP0003937_abnormal_limbs/digits/tail_de1.32636465
38MP0004197_abnormal_fetal_growth/weight/1.31646566
39MP0003941_abnormal_skin_development1.30962677
40MP0002084_abnormal_developmental_patter1.28935338
41MP0003763_abnormal_thymus_physiology1.28735612
42MP0003984_embryonic_growth_retardation1.26661861
43MP0006035_abnormal_mitochondrial_morpho1.26235331
44MP0002210_abnormal_sex_determination1.26107077
45MP0002080_prenatal_lethality1.24589956
46MP0002160_abnormal_reproductive_system1.23532159
47MP0010352_gastrointestinal_tract_polyps1.23243334
48MP0002088_abnormal_embryonic_growth/wei1.22594515
49MP0000313_abnormal_cell_death1.22249594
50MP0003186_abnormal_redox_activity1.21361074
51MP0004808_abnormal_hematopoietic_stem1.18465945
52MP0004133_heterotaxia1.16986989
53MP0003806_abnormal_nucleotide_metabolis1.16935200
54MP0009379_abnormal_foot_pigmentation1.14104362
55MP0000358_abnormal_cell_content/1.13355568
56MP0002877_abnormal_melanocyte_morpholog1.12628051
57MP0003121_genomic_imprinting1.12554029
58MP0010307_abnormal_tumor_latency1.11811250
59MP0004381_abnormal_hair_follicle1.11542671
60MP0003315_abnormal_perineum_morphology1.10947015
61MP0002086_abnormal_extraembryonic_tissu1.10154380
62MP0003705_abnormal_hypodermis_morpholog1.09774762
63MP0002019_abnormal_tumor_incidence1.09767366
64MP0009333_abnormal_splenocyte_physiolog1.08921920
65MP0000579_abnormal_nail_morphology1.08801413
66MP0002009_preneoplasia1.08685061
67MP0001145_abnormal_male_reproductive1.07833248
68MP0002796_impaired_skin_barrier1.07784418
69MP0002111_abnormal_tail_morphology1.07615974
70MP0002249_abnormal_larynx_morphology1.06796014
71MP0010234_abnormal_vibrissa_follicle1.06593337
72MP0005076_abnormal_cell_differentiation1.06409031
73MP0005174_abnormal_tail_pigmentation1.05412253
74MP0001986_abnormal_taste_sensitivity1.05264226
75MP0001188_hyperpigmentation0.99086342
76MP0004134_abnormal_chest_morphology0.98194352
77MP0000653_abnormal_sex_gland0.94773001
78MP0003950_abnormal_plasma_membrane0.92955638
79MP0000432_abnormal_head_morphology0.92705930
80MP0009703_decreased_birth_body0.92185704
81MP0000703_abnormal_thymus_morphology0.91680047
82MP0001286_abnormal_eye_development0.91328209
83MP0008995_early_reproductive_senescence0.90499879
84MP0002095_abnormal_skin_pigmentation0.89514487
85MP0000462_abnormal_digestive_system0.88917174
86MP0000762_abnormal_tongue_morphology0.88043616
87MP0002233_abnormal_nose_morphology0.87808984
88MP0005389_reproductive_system_phenotype0.87514689
89MP0002132_abnormal_respiratory_system0.86433663
90MP0004147_increased_porphyrin_level0.85970448
91MP0002114_abnormal_axial_skeleton0.85577903
92MP0001929_abnormal_gametogenesis0.85210826
93MP0001485_abnormal_pinna_reflex0.85035695
94MP0000647_abnormal_sebaceous_gland0.82428169
95MP0000465_gastrointestinal_hemorrhage0.82251201
96MP0000613_abnormal_salivary_gland0.81238754
97MP0000049_abnormal_middle_ear0.80395487
98MP0003221_abnormal_cardiomyocyte_apopto0.79180379
99MP0002932_abnormal_joint_morphology0.79066975
100MP0002102_abnormal_ear_morphology0.78451343
101MP0003938_abnormal_ear_development0.78310923
102MP0009053_abnormal_anal_canal0.77539655
103MP0002092_abnormal_eye_morphology0.77330513
104MP0005397_hematopoietic_system_phenotyp0.77144278
105MP0001545_abnormal_hematopoietic_system0.77144278
106MP0009278_abnormal_bone_marrow0.75782443
107MP0000537_abnormal_urethra_morphology0.75679341
108MP0000015_abnormal_ear_pigmentation0.74827289
109MP0003755_abnormal_palate_morphology0.74596084
110MP0002398_abnormal_bone_marrow0.73437295
111MP0003119_abnormal_digestive_system0.73102365
112MP0002697_abnormal_eye_size0.72766301
113MP0003943_abnormal_hepatobiliary_system0.71853339
114MP0002075_abnormal_coat/hair_pigmentati0.71615344
115MP0000428_abnormal_craniofacial_morphol0.71098815
116MP0005395_other_phenotype0.70368790
117MP0002234_abnormal_pharynx_morphology0.69437554
118MP0002722_abnormal_immune_system0.69279339
119MP0005384_cellular_phenotype0.69225341
120MP0000383_abnormal_hair_follicle0.69147456
121MP0003385_abnormal_body_wall0.69089026
122MP0000689_abnormal_spleen_morphology0.68873428
123MP0006072_abnormal_retinal_apoptosis0.68666572
124MP0010678_abnormal_skin_adnexa0.68150889
125MP0001119_abnormal_female_reproductive0.67595002
126MP0003861_abnormal_nervous_system0.67348171
127MP0001186_pigmentation_phenotype0.66685043
128MP0001915_intracranial_hemorrhage0.66152727
129MP0005408_hypopigmentation0.66099152
130MP0002116_abnormal_craniofacial_bone0.65578429
131MP0002060_abnormal_skin_morphology0.65239812
132MP0005501_abnormal_skin_physiology0.65076751
133MP0001346_abnormal_lacrimal_gland0.64679379
134MP0001529_abnormal_vocalization0.63023716
135MP0006036_abnormal_mitochondrial_physio0.61633914
136MP0003935_abnormal_craniofacial_develop0.61578999
137MP0000627_abnormal_mammary_gland0.61011099
138MP0003699_abnormal_female_reproductive0.58488777
139MP0002269_muscular_atrophy0.57020775

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.93871616
2Chromsome breakage (HP:0040012)4.84358482
3Reticulocytopenia (HP:0001896)4.47951251
4Duplicated collecting system (HP:0000081)4.15010462
5Abnormality of the renal collecting system (HP:0004742)3.87672176
6Abnormality of cells of the erythroid lineage (HP:0012130)3.76529439
7Abnormal number of erythroid precursors (HP:0012131)3.64794095
8Birth length less than 3rd percentile (HP:0003561)3.42803082
9Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.34350224
10Abnormality of alanine metabolism (HP:0010916)3.34350224
11Hyperalaninemia (HP:0003348)3.34350224
12Breast hypoplasia (HP:0003187)3.22397171
13Asplenia (HP:0001746)3.20615291
14Abnormality of glycolysis (HP:0004366)3.15157110
15Absent radius (HP:0003974)3.12038063
16Abnormality of the preputium (HP:0100587)3.06717991
17Increased serum pyruvate (HP:0003542)3.02131740
18Cerebral hypomyelination (HP:0006808)3.01151103
19Medulloblastoma (HP:0002885)2.94917794
20Aplastic anemia (HP:0001915)2.94510996
21Aplasia/Hypoplasia of the spleen (HP:0010451)2.92685527
22Absent forearm bone (HP:0003953)2.89506624
23Aplasia involving forearm bones (HP:0009822)2.89506624
24Supernumerary spleens (HP:0009799)2.87698115
25Meckel diverticulum (HP:0002245)2.86507620
26Abnormality of the ileum (HP:0001549)2.84045724
27Abnormality of chromosome stability (HP:0003220)2.83627282
28Abnormality of methionine metabolism (HP:0010901)2.77936971
29Multiple enchondromatosis (HP:0005701)2.74366146
30Premature graying of hair (HP:0002216)2.73742522
31Abnormality of homocysteine metabolism (HP:0010919)2.69676870
32Homocystinuria (HP:0002156)2.69676870
33Macrocytic anemia (HP:0001972)2.69512296
34Rough bone trabeculation (HP:0100670)2.67603332
35Increased nuchal translucency (HP:0010880)2.65306848
36Ectopic kidney (HP:0000086)2.61509558
37Selective tooth agenesis (HP:0001592)2.61033570
38Abnormality of the fetal cardiovascular system (HP:0010948)2.57077504
39Abnormal umbilical cord blood vessels (HP:0011403)2.57077504
40Single umbilical artery (HP:0001195)2.57077504
41Absent thumb (HP:0009777)2.53917919
42Pallor (HP:0000980)2.53758162
43Myelodysplasia (HP:0002863)2.50634433
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.50122554
45Colon cancer (HP:0003003)2.43437404
4611 pairs of ribs (HP:0000878)2.41600756
47Abnormality of serum amino acid levels (HP:0003112)2.39763572
48Patellar aplasia (HP:0006443)2.36959020
49Oral leukoplakia (HP:0002745)2.33521513
50Abnormal number of incisors (HP:0011064)2.33444591
51Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28566444
52Cortical dysplasia (HP:0002539)2.26167202
53Abnormal lung lobation (HP:0002101)2.24634257
54Aplasia/Hypoplasia of the patella (HP:0006498)2.23507020
55Abnormality of DNA repair (HP:0003254)2.22706177
56Type I transferrin isoform profile (HP:0003642)2.22628481
57Small intestinal stenosis (HP:0012848)2.21961399
58Duodenal stenosis (HP:0100867)2.21961399
59Microvesicular hepatic steatosis (HP:0001414)2.20534276
60Ureteral duplication (HP:0000073)2.15432220
61Sloping forehead (HP:0000340)2.15249158
62Bone marrow hypocellularity (HP:0005528)2.13509871
63Progressive muscle weakness (HP:0003323)2.13483357
64Abnormality of sulfur amino acid metabolism (HP:0004339)2.12492221
65Triphalangeal thumb (HP:0001199)2.11838283
66Horseshoe kidney (HP:0000085)2.11742130
67Esophageal atresia (HP:0002032)2.10320860
68Duplication of thumb phalanx (HP:0009942)2.05041626
69Intestinal atresia (HP:0011100)2.03814747
70Abnormal trabecular bone morphology (HP:0100671)2.01682082
71Ependymoma (HP:0002888)2.01587106
72Microglossia (HP:0000171)2.01213069
73Abnormalities of placenta or umbilical cord (HP:0001194)2.00497643
74Abnormality of cochlea (HP:0000375)2.00199044
75Rhabdomyosarcoma (HP:0002859)1.99532541
76Abnormality of the pons (HP:0007361)1.98190097
77Short thumb (HP:0009778)1.95920623
78Arteriovenous malformation (HP:0100026)1.95762445
79Hypoplasia of the pons (HP:0012110)1.94892149
80Nephroblastoma (Wilms tumor) (HP:0002667)1.94817399
81Increased serum lactate (HP:0002151)1.94597288
82Abnormality of the duodenum (HP:0002246)1.94334009
83Carpal bone hypoplasia (HP:0001498)1.93462960
84Impulsivity (HP:0100710)1.91960378
85Progressive external ophthalmoplegia (HP:0000590)1.90955129
86Overlapping toe (HP:0001845)1.90796133
87Choanal atresia (HP:0000453)1.90618145
88Megaloblastic anemia (HP:0001889)1.90222923
89Rib fusion (HP:0000902)1.89949989
90Neoplasm of the oral cavity (HP:0100649)1.87617634
91Septo-optic dysplasia (HP:0100842)1.86211105
92Pancytopenia (HP:0001876)1.85531504
93Supernumerary bones of the axial skeleton (HP:0009144)1.85523122
94Abnormality of the carotid arteries (HP:0005344)1.85421807
95Abnormality of the labia minora (HP:0012880)1.85218674
96Tracheoesophageal fistula (HP:0002575)1.84997217
97Lymphoma (HP:0002665)1.84854488
98Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.84173776
99Embryonal renal neoplasm (HP:0011794)1.83323099
100Neoplasm of the pancreas (HP:0002894)1.82149455
101Facial cleft (HP:0002006)1.81931987
102Adrenal hypoplasia (HP:0000835)1.81746096
103Proximal placement of thumb (HP:0009623)1.81393321
104Trismus (HP:0000211)1.81276977
105Abnormality of aspartate family amino acid metabolism (HP:0010899)1.80539673
106Increased hepatocellular lipid droplets (HP:0006565)1.80224146
107Gastrointestinal atresia (HP:0002589)1.79472926
108Deviation of the thumb (HP:0009603)1.78789290
109Missing ribs (HP:0000921)1.78169606
110Pancreatic islet-cell hyperplasia (HP:0004510)1.77945134
111Stenosis of the external auditory canal (HP:0000402)1.77066722
112Premature ovarian failure (HP:0008209)1.76841562
113Basal cell carcinoma (HP:0002671)1.76782362
114Exertional dyspnea (HP:0002875)1.76652221
115Reduced antithrombin III activity (HP:0001976)1.76207121
116Acute lymphatic leukemia (HP:0006721)1.75912993
117Cafe-au-lait spot (HP:0000957)1.75716612
118Deep philtrum (HP:0002002)1.75501792
119Hypoplastic pelvis (HP:0008839)1.72545525
120Clubbing of toes (HP:0100760)1.72481644
121Atresia of the external auditory canal (HP:0000413)1.72307318
122Short middle phalanx of the 5th finger (HP:0004220)1.71453140
123CNS hypomyelination (HP:0003429)1.70292367
124Neoplasm of the colon (HP:0100273)1.70103842
125Squamous cell carcinoma (HP:0002860)1.69116893
126Abnormal spermatogenesis (HP:0008669)1.68728222
127Hypoplasia of the radius (HP:0002984)1.68506339
128Secondary amenorrhea (HP:0000869)1.68480930
129Renal agenesis (HP:0000104)1.66673996
130Poikiloderma (HP:0001029)1.66268511
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.65574077
132Volvulus (HP:0002580)1.65565817
133Agnosia (HP:0010524)1.64463356
134Glioma (HP:0009733)1.63881053
135Cerebral edema (HP:0002181)1.63378270
136Morphological abnormality of the inner ear (HP:0011390)1.62939071
137Abnormality of the umbilical cord (HP:0010881)1.62343000
138Abnormal protein glycosylation (HP:0012346)1.62117502
139Abnormal glycosylation (HP:0012345)1.62117502
140Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.62117502
141Abnormal protein N-linked glycosylation (HP:0012347)1.62117502
142Abnormality of the septum pellucidum (HP:0007375)1.61734098
143Acute myeloid leukemia (HP:0004808)1.60938287
144IgM deficiency (HP:0002850)1.59692690
145Cellular immunodeficiency (HP:0005374)1.58972322
146Supernumerary ribs (HP:0005815)1.58808728
147Septate vagina (HP:0001153)1.58787164
148Postnatal microcephaly (HP:0005484)1.57771324
149Sensory axonal neuropathy (HP:0003390)1.53560158
150Astrocytoma (HP:0009592)1.51595986
151Abnormality of the astrocytes (HP:0100707)1.51595986
152Aplasia/Hypoplasia of the sternum (HP:0006714)1.50808127
153Acute encephalopathy (HP:0006846)1.50451357

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.87298620
2BUB13.72582745
3WEE13.45495468
4NEK13.12047707
5SRPK12.96583157
6STK162.72390867
7MKNK12.47602059
8VRK22.32719125
9TLK12.26723159
10TSSK62.21895684
11PLK42.20311092
12MKNK22.16919230
13TTK2.14624774
14VRK12.04947556
15EIF2AK12.04015883
16ZAK1.97099888
17CDK71.97082565
18NME21.95353703
19RPS6KB21.88104629
20TAF11.75409780
21ATR1.73496726
22EIF2AK31.72309413
23ACVR1B1.71398607
24PLK11.67927867
25CHEK21.67148714
26NEK21.63381083
27PASK1.58267847
28PIM21.53744462
29PLK31.49165772
30SCYL21.46987141
31BRSK21.46550836
32TRIM281.45215534
33AURKB1.44964662
34DYRK31.36883471
35CHEK11.32708877
36CDK121.29558312
37AURKA1.27872758
38PDK21.25527843
39EPHA21.23960413
40TESK21.21824377
41EEF2K1.18271960
42CLK11.11924162
43PBK1.08496774
44MAP3K81.07352697
45CDK191.06142263
46ATM1.04614439
47SMG11.00315858
48NME10.99213308
49RPS6KA50.98889912
50IRAK40.97758819
51CDK40.97256166
52MAPKAPK50.96938673
53ERBB40.96792565
54STK100.96547923
55MAP3K100.92386879
56IRAK30.91968109
57STK40.87032240
58CDK20.86171369
59MST1R0.85033229
60EIF2AK20.84628683
61CSNK2A20.84254504
62MAP3K110.83949971
63PIM10.83509830
64BRD40.83153327
65BMPR1B0.80728409
66NUAK10.80121310
67RPS6KA40.77760272
68YES10.75715727
69PNCK0.75085875
70IRAK10.74432424
71CDK80.74298684
72TAOK20.73760336
73TGFBR10.73169066
74STK240.71746923
75CCNB10.70771547
76CDK10.69978606
77STK390.69746780
78CSNK2A10.69550354
79NEK60.67516150
80LATS20.67326636
81MET0.67294707
82LATS10.65940858
83BCR0.64933147
84ERBB30.64765173
85STK30.64050917
86CSNK1E0.62934605
87CDK60.62729639
88TNIK0.62634623
89FGFR10.61561737
90IRAK20.60932560
91PAK20.60929633
92TEC0.59344867
93BTK0.57986311
94CDK90.57629645
95CSNK1A1L0.57020671
96PAK10.56410287
97DYRK20.56133930
98FLT30.55621887
99LIMK10.55293935
100ALK0.52567655
101MAP2K30.52409028
102MST40.50573292
103CSNK1G30.50470890
104BRAF0.49358148
105MAP4K10.44402374
106BRSK10.43354080
107PRKDC0.43267342
108UHMK10.43021978
109CSNK1D0.41952624
110STK38L0.38443025
111CDK30.38302872
112CAMK1G0.37585304
113PAK40.37260456
114FGR0.36869720
115PRKCI0.35267143
116CSNK1G10.34834132
117RPS6KB10.34151779
118MTOR0.34132447
119AKT20.33949054
120TRPM70.33829464
121MAPK140.33580336
122MAPKAPK20.33569910
123RAF10.33552540
124IKBKB0.33376473
125PLK20.31242390
126MAPK10.29077608
127ILK0.27028942
128CAMK1D0.25885432
129DAPK10.23842197

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.62110133
2Mismatch repair_Homo sapiens_hsa034304.13965017
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.90749167
4Ribosome_Homo sapiens_hsa030103.60646867
5RNA polymerase_Homo sapiens_hsa030203.47225402
6Homologous recombination_Homo sapiens_hsa034403.19396312
7Spliceosome_Homo sapiens_hsa030403.19087519
8Nucleotide excision repair_Homo sapiens_hsa034202.91571633
9RNA transport_Homo sapiens_hsa030132.87231081
10Base excision repair_Homo sapiens_hsa034102.86060116
11Fanconi anemia pathway_Homo sapiens_hsa034602.81661542
12One carbon pool by folate_Homo sapiens_hsa006702.65390483
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.46972267
14Proteasome_Homo sapiens_hsa030502.44019859
15Cell cycle_Homo sapiens_hsa041102.42337131
16Pyrimidine metabolism_Homo sapiens_hsa002402.40235015
17Basal transcription factors_Homo sapiens_hsa030222.12597759
18Non-homologous end-joining_Homo sapiens_hsa034502.04204886
19RNA degradation_Homo sapiens_hsa030181.94881431
20mRNA surveillance pathway_Homo sapiens_hsa030151.81041585
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.77214293
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.76003504
23Pyruvate metabolism_Homo sapiens_hsa006201.47862061
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36310454
25Purine metabolism_Homo sapiens_hsa002301.36218788
26p53 signaling pathway_Homo sapiens_hsa041151.34634274
27Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.31761996
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.28778263
29Carbon metabolism_Homo sapiens_hsa012001.23857267
30Protein export_Homo sapiens_hsa030601.22552502
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.21803794
32Propanoate metabolism_Homo sapiens_hsa006401.20986632
33Systemic lupus erythematosus_Homo sapiens_hsa053221.15945824
34Epstein-Barr virus infection_Homo sapiens_hsa051691.01207561
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.96024709
36Vitamin B6 metabolism_Homo sapiens_hsa007500.93564157
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.93169098
38Herpes simplex infection_Homo sapiens_hsa051680.83477141
39Viral carcinogenesis_Homo sapiens_hsa052030.81555884
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80569075
41Arginine biosynthesis_Homo sapiens_hsa002200.80312081
42Sulfur relay system_Homo sapiens_hsa041220.79683159
43Steroid biosynthesis_Homo sapiens_hsa001000.75954173
44Folate biosynthesis_Homo sapiens_hsa007900.75155751
45Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75000626
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72855300
47Sulfur metabolism_Homo sapiens_hsa009200.72285105
48Pentose phosphate pathway_Homo sapiens_hsa000300.70740571
49MicroRNAs in cancer_Homo sapiens_hsa052060.70468320
50Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.69761234
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.68394555
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68065466
53Lysine degradation_Homo sapiens_hsa003100.66069644
54HTLV-I infection_Homo sapiens_hsa051660.61837831
55Ether lipid metabolism_Homo sapiens_hsa005650.59414344
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.57919490
57Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57573960
58Linoleic acid metabolism_Homo sapiens_hsa005910.56927554
59Arachidonic acid metabolism_Homo sapiens_hsa005900.56111347
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.54999726
61Primary immunodeficiency_Homo sapiens_hsa053400.54713579
62Basal cell carcinoma_Homo sapiens_hsa052170.53267050
63Small cell lung cancer_Homo sapiens_hsa052220.52153849
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.50382756
65Galactose metabolism_Homo sapiens_hsa000520.48716816
66Adherens junction_Homo sapiens_hsa045200.48633882
67Oocyte meiosis_Homo sapiens_hsa041140.48589761
68TGF-beta signaling pathway_Homo sapiens_hsa043500.48335668
69Huntingtons disease_Homo sapiens_hsa050160.48248893
70Glutathione metabolism_Homo sapiens_hsa004800.48181569
71Cyanoamino acid metabolism_Homo sapiens_hsa004600.47185308
72Hippo signaling pathway_Homo sapiens_hsa043900.46327023
73Alcoholism_Homo sapiens_hsa050340.45958999
74Fatty acid metabolism_Homo sapiens_hsa012120.43908538
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43038062
76Antigen processing and presentation_Homo sapiens_hsa046120.41592554
77Thyroid cancer_Homo sapiens_hsa052160.39218760
78Notch signaling pathway_Homo sapiens_hsa043300.38466556
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37823525
80Hematopoietic cell lineage_Homo sapiens_hsa046400.36726284
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35783653
82Arginine and proline metabolism_Homo sapiens_hsa003300.34857831
83Measles_Homo sapiens_hsa051620.34821918
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.34673555
85Vitamin digestion and absorption_Homo sapiens_hsa049770.34583026
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.33799927
87Sphingolipid metabolism_Homo sapiens_hsa006000.33006530
88Hedgehog signaling pathway_Homo sapiens_hsa043400.32432192
89Shigellosis_Homo sapiens_hsa051310.32351168
90Fructose and mannose metabolism_Homo sapiens_hsa000510.32119600
91N-Glycan biosynthesis_Homo sapiens_hsa005100.31446720
92Wnt signaling pathway_Homo sapiens_hsa043100.31042500
93Prostate cancer_Homo sapiens_hsa052150.30496720
94Selenocompound metabolism_Homo sapiens_hsa004500.30364449
95Apoptosis_Homo sapiens_hsa042100.30359888
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30291775
97Pathways in cancer_Homo sapiens_hsa052000.28920284
98Tight junction_Homo sapiens_hsa045300.27936259
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27904422
100Parkinsons disease_Homo sapiens_hsa050120.27365249
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26690785
102Autoimmune thyroid disease_Homo sapiens_hsa053200.26616237
103Hepatitis B_Homo sapiens_hsa051610.25585503
104Metabolic pathways_Homo sapiens_hsa011000.25275738
105Drug metabolism - other enzymes_Homo sapiens_hsa009830.25254363
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.24172161
107Fatty acid biosynthesis_Homo sapiens_hsa000610.23392476
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23028872
109Alzheimers disease_Homo sapiens_hsa050100.22799329
110Asthma_Homo sapiens_hsa053100.22604404
111Fatty acid elongation_Homo sapiens_hsa000620.22493408
112Colorectal cancer_Homo sapiens_hsa052100.22238036
113Bladder cancer_Homo sapiens_hsa052190.21798337
114Allograft rejection_Homo sapiens_hsa053300.21478417
115Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21362621
116Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.21333644
117Legionellosis_Homo sapiens_hsa051340.21044523
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.19899770
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18275922
120Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.18118641
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17967148
122Acute myeloid leukemia_Homo sapiens_hsa052210.17680222
123Biosynthesis of amino acids_Homo sapiens_hsa012300.17241613
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.16983129
125Oxidative phosphorylation_Homo sapiens_hsa001900.16470821
126Chronic myeloid leukemia_Homo sapiens_hsa052200.15883431
127Graft-versus-host disease_Homo sapiens_hsa053320.15087669
128Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.13503084
129Melanoma_Homo sapiens_hsa052180.10554729
130Peroxisome_Homo sapiens_hsa041460.08682643
131beta-Alanine metabolism_Homo sapiens_hsa004100.07506884

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