PVRIG2P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sequestering of actin monomers (GO:0042989)6.79624658
2positive thymic T cell selection (GO:0045059)6.15241293
3negative T cell selection (GO:0043383)6.02594265
4positive T cell selection (GO:0043368)5.92935035
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.80216195
6negative thymic T cell selection (GO:0045060)5.70189405
7ATP synthesis coupled proton transport (GO:0015986)5.16852922
8energy coupled proton transport, down electrochemical gradient (GO:0015985)5.16852922
9thymic T cell selection (GO:0045061)4.90870808
10cytidine deamination (GO:0009972)4.35339660
11cytidine metabolic process (GO:0046087)4.35339660
12cytidine catabolic process (GO:0006216)4.35339660
13protein neddylation (GO:0045116)4.32981318
14regulation of glucokinase activity (GO:0033131)4.32341402
15regulation of hexokinase activity (GO:1903299)4.32341402
16Arp2/3 complex-mediated actin nucleation (GO:0034314)4.31238026
17T cell selection (GO:0045058)4.22415977
18positive regulation of B cell differentiation (GO:0045579)4.20585173
19alkaloid metabolic process (GO:0009820)4.08859261
20viral transcription (GO:0019083)3.96962432
21translational termination (GO:0006415)3.84684320
22negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 3.82212638
23positive regulation of gastrulation (GO:2000543)3.79251201
24leukocyte aggregation (GO:0070486)3.78365050
25DNA damage response, detection of DNA damage (GO:0042769)3.58978819
26pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.58009420
27positive regulation of lamellipodium assembly (GO:0010592)3.56926917
28respiratory electron transport chain (GO:0022904)3.46534747
29pyrimidine ribonucleoside catabolic process (GO:0046133)3.44430726
30actin nucleation (GO:0045010)3.41773640
31translational elongation (GO:0006414)3.40672891
32electron transport chain (GO:0022900)3.38023132
33DNA deamination (GO:0045006)3.27959758
34regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.27952291
35negative regulation of B cell apoptotic process (GO:0002903)3.27188160
36ATP biosynthetic process (GO:0006754)3.21186077
37monocyte chemotaxis (GO:0002548)3.19043682
38grooming behavior (GO:0007625)3.18622624
39dorsal/ventral neural tube patterning (GO:0021904)3.18477394
40mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.15811659
41regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3.14863272
42positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.13473164
43regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.13473164
44cellular protein complex disassembly (GO:0043624)3.11354079
45protein K6-linked ubiquitination (GO:0085020)3.05272904
46peptidyl-arginine omega-N-methylation (GO:0035247)3.01377522
47negative regulation of T cell apoptotic process (GO:0070233)3.00584661
48SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.99815935
49DNA synthesis involved in DNA repair (GO:0000731)2.95757642
50negative regulation of lymphocyte apoptotic process (GO:0070229)2.95641568
51positive regulation of protein sumoylation (GO:0033235)2.95596505
52mannosylation (GO:0097502)2.93454163
53cotranslational protein targeting to membrane (GO:0006613)2.93413581
54tolerance induction (GO:0002507)2.93043396
55positive regulation of interleukin-4 production (GO:0032753)2.92251556
56positive regulation of calcium-mediated signaling (GO:0050850)2.90240423
57regulation of T cell tolerance induction (GO:0002664)2.89077972
58inner mitochondrial membrane organization (GO:0007007)2.87140711
59deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.86328374
60regulation of regulatory T cell differentiation (GO:0045589)2.86058770
61phospholipid efflux (GO:0033700)2.85468166
62protein targeting to ER (GO:0045047)2.85104981
63protein localization to endoplasmic reticulum (GO:0070972)2.84705154
64aggressive behavior (GO:0002118)2.82526270
65maturation of SSU-rRNA (GO:0030490)2.82261295
66protein complex disassembly (GO:0043241)2.82149128
67regulation of B cell differentiation (GO:0045577)2.80674311
68ubiquinone biosynthetic process (GO:0006744)2.80255927
69regulation of respiratory burst (GO:0060263)2.80092596
70negative regulation of T cell differentiation (GO:0045581)2.79066368
71cytolysis (GO:0019835)2.78988598
72viral life cycle (GO:0019058)2.78144800
73negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.76606265
74positive regulation of lamellipodium organization (GO:1902745)2.75518814
75ribosomal small subunit assembly (GO:0000028)2.75382966
76somite rostral/caudal axis specification (GO:0032525)2.74917432
77metallo-sulfur cluster assembly (GO:0031163)2.73724561
78iron-sulfur cluster assembly (GO:0016226)2.73724561
79nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.72741658
80macromolecular complex disassembly (GO:0032984)2.71226782
81T cell migration (GO:0072678)2.71134209
82purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.70929452
83positive regulation of tolerance induction (GO:0002645)2.70246955
84NAD biosynthetic process (GO:0009435)2.68770930
85histone H4-K8 acetylation (GO:0043982)2.68545849
86histone H4-K5 acetylation (GO:0043981)2.68545849
87primitive streak formation (GO:0090009)2.67898546
88establishment of protein localization to endoplasmic reticulum (GO:0072599)2.65753486
89pyrimidine nucleotide catabolic process (GO:0006244)2.65591742
90indolalkylamine metabolic process (GO:0006586)2.63778943
91T cell receptor signaling pathway (GO:0050852)2.60584049
92base-excision repair, AP site formation (GO:0006285)2.59537825
93purine nucleoside triphosphate biosynthetic process (GO:0009145)2.55713849
94immunoglobulin mediated immune response (GO:0016064)2.53404342
95galactose catabolic process (GO:0019388)2.53325443
96dopaminergic neuron differentiation (GO:0071542)2.53164754
97regulation of interleukin-4 production (GO:0032673)2.50714371
98Peyers patch development (GO:0048541)2.50655257
99mucosal-associated lymphoid tissue development (GO:0048537)2.50655257
100positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.49730538

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse6.53353072
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse6.43752238
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.43936760
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.21634037
5SRY_22984422_ChIP-ChIP_TESTIS_Rat2.90280246
6CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.72107050
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.29642104
8XRN2_22483619_ChIP-Seq_HELA_Human2.19495560
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.17866480
10MYC_22102868_ChIP-Seq_BL_Human2.17334854
11CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.11381826
12CIITA_25753668_ChIP-Seq_RAJI_Human2.00196482
13GABP_17652178_ChIP-ChIP_JURKAT_Human1.93001207
14FOXM1_23109430_ChIP-Seq_U2OS_Human1.91769653
15VDR_21846776_ChIP-Seq_THP-1_Human1.88071110
16ETS1_20019798_ChIP-Seq_JURKAT_Human1.87017065
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.81769178
18STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.81591684
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.80181898
20MAF_26560356_Chip-Seq_TH2_Human1.78549749
21BCL6_27268052_Chip-Seq_Bcells_Human1.75723484
22EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.75471982
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.72902557
24MYC_18555785_ChIP-Seq_MESCs_Mouse1.69567627
25CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.67080730
26CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.66753735
27THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63803656
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.62341127
29SCL_19346495_ChIP-Seq_HPC-7_Human1.59743648
30UTX_26944678_Chip-Seq_JUKART_Human1.58888139
31CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.57717057
32EST1_17652178_ChIP-ChIP_JURKAT_Human1.57656368
33YY1_22570637_ChIP-Seq_MALME-3M_Human1.56223979
34TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55878870
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.53983626
36VDR_23849224_ChIP-Seq_CD4+_Human1.51273711
37ELF1_20517297_ChIP-Seq_JURKAT_Human1.51229897
38STAT4_19710469_ChIP-ChIP_TH1__Mouse1.50307415
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.49944721
40MYC_18358816_ChIP-ChIP_MESCs_Mouse1.49544637
41RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.49306304
42P68_20966046_ChIP-Seq_HELA_Human1.46686355
43CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.45176563
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.44549918
45IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.39499884
46FOXP3_21729870_ChIP-Seq_TREG_Human1.38234444
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38000919
48CTCF_26484167_Chip-Seq_Bcells_Mouse1.35471356
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.32019735
50EGR1_19032775_ChIP-ChIP_M12_Human1.31068609
51RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.31018839
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.31009935
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.30603964
54EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.29613719
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.26760045
56BCOR_27268052_Chip-Seq_Bcells_Human1.26511534
57SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.26438613
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.26403207
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.26096695
60IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.25413712
61ERG_21242973_ChIP-ChIP_JURKAT_Human1.23701039
62ERA_21632823_ChIP-Seq_H3396_Human1.20555261
63MAF_26560356_Chip-Seq_TH1_Human1.17677772
64MYB_26560356_Chip-Seq_TH2_Human1.17320223
65CTCF_20526341_ChIP-Seq_ESCs_Human1.17152206
66KDM5A_27292631_Chip-Seq_BREAST_Human1.16752323
67SRF_21415370_ChIP-Seq_HL-1_Mouse1.15151725
68TET1_21451524_ChIP-Seq_MESCs_Mouse1.14781304
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13707453
70LXR_22292898_ChIP-Seq_THP-1_Human1.13343198
71E2F1_20622854_ChIP-Seq_HELA_Human1.10853069
72PHF8_20622854_ChIP-Seq_HELA_Human1.10798415
73SA1_27219007_Chip-Seq_ERYTHROID_Human1.10585081
74MYC_19030024_ChIP-ChIP_MESCs_Mouse1.09988659
75TTF2_22483619_ChIP-Seq_HELA_Human1.08976863
76IRF8_22096565_ChIP-ChIP_GC-B_Human1.08572320
77E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06580493
78TP53_20018659_ChIP-ChIP_R1E_Mouse1.06300391
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.05249677
80P300_27268052_Chip-Seq_Bcells_Human1.03228560
81GABP_19822575_ChIP-Seq_HepG2_Human1.03090117
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02581344
83BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02193195
84CREB1_15753290_ChIP-ChIP_HEK293T_Human0.99827487
85E2F1_18555785_ChIP-Seq_MESCs_Mouse0.98592738
86CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97525570
87EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96559351
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96558360
89MYB_26560356_Chip-Seq_TH1_Human0.95865855
90CBX2_27304074_Chip-Seq_ESCs_Mouse0.95444711
91MYC_19079543_ChIP-ChIP_MESCs_Mouse0.94904487
92CTCF_27219007_Chip-Seq_Bcells_Human0.94060854
93EZH2_27304074_Chip-Seq_ESCs_Mouse0.93344039
94KDM2B_26808549_Chip-Seq_DND41_Human0.90774692
95GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90434065
96FOXP1_21924763_ChIP-Seq_HESCs_Human0.90052191
97BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.89792756
98RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.89557924
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.89456229
100SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.87196045

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.51892977
2MP0005671_abnormal_response_to3.34113838
3MP0002277_abnormal_respiratory_mucosa3.28656613
4MP0001188_hyperpigmentation3.26451868
5MP0005367_renal/urinary_system_phenotyp2.66465410
6MP0000516_abnormal_urinary_system2.66465410
7MP0008961_abnormal_basal_metabolism2.60133038
8MP0001346_abnormal_lacrimal_gland2.54366821
9MP0009840_abnormal_foam_cell2.52139465
10MP0009333_abnormal_splenocyte_physiolog2.36491934
11MP0002933_joint_inflammation2.31403635
12MP0003866_abnormal_defecation2.20323981
13MP0001873_stomach_inflammation2.14953609
14MP0005360_urolithiasis2.07400641
15MP0005084_abnormal_gallbladder_morpholo2.01601375
16MP0001905_abnormal_dopamine_level2.00304826
17MP0002163_abnormal_gland_morphology1.95936984
18MP0000465_gastrointestinal_hemorrhage1.88098018
19MP0005645_abnormal_hypothalamus_physiol1.86195273
20MP0004133_heterotaxia1.82919921
21MP0003763_abnormal_thymus_physiology1.76410448
22MP0001529_abnormal_vocalization1.69364126
23MP0008058_abnormal_DNA_repair1.67271054
24MP0002249_abnormal_larynx_morphology1.66298105
25MP0002822_catalepsy1.65456971
26MP0003436_decreased_susceptibility_to1.57150274
27MP0008995_early_reproductive_senescence1.53696648
28MP0006292_abnormal_olfactory_placode1.53153822
29MP0005670_abnormal_white_adipose1.52650935
30MP0005000_abnormal_immune_tolerance1.52314205
31MP0004145_abnormal_muscle_electrophysio1.44983712
32MP0002938_white_spotting1.42782010
33MP0009278_abnormal_bone_marrow1.38286893
34MP0008004_abnormal_stomach_pH1.37714979
35MP0009785_altered_susceptibility_to1.32899264
36MP0005503_abnormal_tendon_morphology1.27481229
37MP0002932_abnormal_joint_morphology1.26910742
38MP0009697_abnormal_copulation1.25660125
39MP0000703_abnormal_thymus_morphology1.25244310
40MP0005623_abnormal_meninges_morphology1.24816854
41MP0003878_abnormal_ear_physiology1.23626168
42MP0005377_hearing/vestibular/ear_phenot1.23626168
43MP0001800_abnormal_humoral_immune1.23024870
44MP0002420_abnormal_adaptive_immunity1.21177208
45MP0001835_abnormal_antigen_presentation1.20001915
46MP0002398_abnormal_bone_marrow1.15851373
47MP0005025_abnormal_response_to1.15170472
48MP0000566_synostosis1.14859270
49MP0003787_abnormal_imprinting1.14388693
50MP0000716_abnormal_immune_system1.13796847
51MP0003279_aneurysm1.13682138
52MP0005379_endocrine/exocrine_gland_phen1.13547771
53MP0001819_abnormal_immune_cell1.12665432
54MP0000569_abnormal_digit_pigmentation1.12468151
55MP0002693_abnormal_pancreas_physiology1.12016931
56MP0000049_abnormal_middle_ear1.07037334
57MP0002722_abnormal_immune_system1.05563003
58MP0001968_abnormal_touch/_nociception1.03557388
59MP0000689_abnormal_spleen_morphology1.02902100
60MP0003111_abnormal_nucleus_morphology1.02028392
61MP0002723_abnormal_immune_serum1.01451294
62MP0002148_abnormal_hypersensitivity_rea1.00705795
63MP0002098_abnormal_vibrissa_morphology0.98870330
64MP0002405_respiratory_system_inflammati0.97751898
65MP0000372_irregular_coat_pigmentation0.96602070
66MP0002429_abnormal_blood_cell0.89918843
67MP0002452_abnormal_antigen_presenting0.88380337
68MP0003786_premature_aging0.87215941
69MP0001853_heart_inflammation0.87163806
70MP0002234_abnormal_pharynx_morphology0.84045194
71MP0005083_abnormal_biliary_tract0.83041090
72MP0003137_abnormal_impulse_conducting0.79513435
73MP0000639_abnormal_adrenal_gland0.78748431
74MP0003123_paternal_imprinting0.76228104
75MP0005187_abnormal_penis_morphology0.75891166
76MP0004858_abnormal_nervous_system0.74350326
77MP0000467_abnormal_esophagus_morphology0.74190579
78MP0003121_genomic_imprinting0.73705940
79MP0003283_abnormal_digestive_organ0.73660576
80MP0000538_abnormal_urinary_bladder0.72351135
81MP0003890_abnormal_embryonic-extraembry0.71404093
82MP0004924_abnormal_behavior0.70656519
83MP0005386_behavior/neurological_phenoty0.70656519
84MP0002019_abnormal_tumor_incidence0.70353131
85MP0002102_abnormal_ear_morphology0.69339942
86MP0003880_abnormal_central_pattern0.69317383
87MP0000470_abnormal_stomach_morphology0.68249138
88MP0003119_abnormal_digestive_system0.68000138
89MP0000681_abnormal_thyroid_gland0.67962876
90MP0000490_abnormal_crypts_of0.66066558
91MP0000678_abnormal_parathyroid_gland0.65711640
92MP0009764_decreased_sensitivity_to0.65417706
93MP0002697_abnormal_eye_size0.64610911
94MP0002282_abnormal_trachea_morphology0.64075150
95MP0001440_abnormal_grooming_behavior0.63717593
96MP0001919_abnormal_reproductive_system0.63243879
97MP0010155_abnormal_intestine_physiology0.63083414
98MP0005075_abnormal_melanosome_morpholog0.62809104
99MP0010307_abnormal_tumor_latency0.61671633
100MP0002733_abnormal_thermal_nociception0.61427986

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)4.46639199
2Abnormal number of erythroid precursors (HP:0012131)4.03940136
3Hypothermia (HP:0002045)4.00730494
4Down-sloping shoulders (HP:0200021)3.81713933
5Severe combined immunodeficiency (HP:0004430)3.64160438
6Median cleft lip (HP:0000161)3.55373904
7Bilateral microphthalmos (HP:0007633)3.50811879
8Abnormality of cells of the erythroid lineage (HP:0012130)3.50757963
9Short tibia (HP:0005736)3.49963064
10Broad distal phalanx of finger (HP:0009836)3.19447183
11Midline defect of the nose (HP:0004122)3.17853505
12Supernumerary spleens (HP:0009799)3.17159384
13Mitochondrial inheritance (HP:0001427)3.16843562
14Abnormality of the phalanges of the hallux (HP:0010057)3.10975947
15Hepatic necrosis (HP:0002605)3.08737670
16Acute necrotizing encephalopathy (HP:0006965)3.08021272
17Aplasia/Hypoplasia of the tibia (HP:0005772)3.05266076
18Elevated erythrocyte sedimentation rate (HP:0003565)3.04055401
19Hepatocellular necrosis (HP:0001404)3.03576941
20Abnormal mitochondria in muscle tissue (HP:0008316)3.02596827
21Combined immunodeficiency (HP:0005387)2.90268518
22Autoimmune hemolytic anemia (HP:0001890)2.84535371
23Abnormality of the parietal bone (HP:0002696)2.79665198
24Occipital encephalocele (HP:0002085)2.69528346
25Abnormal number of incisors (HP:0011064)2.65606601
26Limb dystonia (HP:0002451)2.64568103
27Retinal dysplasia (HP:0007973)2.61573464
28Gastrointestinal infarctions (HP:0005244)2.57079640
29Panhypogammaglobulinemia (HP:0003139)2.51431007
30IgG deficiency (HP:0004315)2.51053791
31Generalized aminoaciduria (HP:0002909)2.50963495
32Cerebral edema (HP:0002181)2.49352765
33Supernumerary bones of the axial skeleton (HP:0009144)2.48866818
34Abnormality of the 4th metacarpal (HP:0010012)2.48020090
35Increased CSF lactate (HP:0002490)2.45670186
36Microretrognathia (HP:0000308)2.41462406
37Acute encephalopathy (HP:0006846)2.40329629
38Supernumerary ribs (HP:0005815)2.38173599
39Hypoalbuminemia (HP:0003073)2.36254325
40Abnormal albumin level (HP:0012116)2.36254325
41Abnormality of the prostate (HP:0008775)2.33152725
42Optic nerve coloboma (HP:0000588)2.31680879
433-Methylglutaconic aciduria (HP:0003535)2.29990657
44Decreased central vision (HP:0007663)2.29807267
45Broad face (HP:0000283)2.27216206
46Progressive macrocephaly (HP:0004481)2.26604387
47Absent rod-and cone-mediated responses on ERG (HP:0007688)2.26296909
48Nausea (HP:0002018)2.25482370
49Hypertensive crisis (HP:0100735)2.23048218
50Abnormal pupillary function (HP:0007686)2.22042679
51Abnormality of T cells (HP:0002843)2.20354993
52Preaxial hand polydactyly (HP:0001177)2.18013170
53Abnormality of T cell physiology (HP:0011840)2.17946445
54Short phalanx of the thumb (HP:0009660)2.14278920
55High anterior hairline (HP:0009890)2.13443618
56Cystic liver disease (HP:0006706)2.12253562
57Abnormality of the columella (HP:0009929)2.12014019
58Cerebellar dysplasia (HP:0007033)2.08803127
59Agammaglobulinemia (HP:0004432)2.08776621
60Neoplasm of the heart (HP:0100544)2.07096833
61Neonatal respiratory distress (HP:0002643)2.02616783
62Milia (HP:0001056)2.00929763
63Nonimmune hydrops fetalis (HP:0001790)2.00295997
64Anencephaly (HP:0002323)1.98956858
65Broad alveolar ridges (HP:0000187)1.98517106
66Short 4th metacarpal (HP:0010044)1.98147129
67Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.98147129
68Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97130222
69Ileus (HP:0002595)1.95001344
70Increased intramyocellular lipid droplets (HP:0012240)1.94135223
71Absent septum pellucidum (HP:0001331)1.93342860
72Prolonged neonatal jaundice (HP:0006579)1.92977657
73Sclerocornea (HP:0000647)1.91825842
74Renal Fanconi syndrome (HP:0001994)1.86871292
75Hypochromic anemia (HP:0001931)1.86084135
76Increased IgM level (HP:0003496)1.85449021
77Increased hepatocellular lipid droplets (HP:0006565)1.83369928
78Limb hypertonia (HP:0002509)1.81960403
79Abnormal delayed hypersensitivity skin test (HP:0002963)1.79257162
80Ureteral stenosis (HP:0000071)1.77111058
81Concave nail (HP:0001598)1.74982130
82Spontaneous abortion (HP:0005268)1.74247243
83Cleft eyelid (HP:0000625)1.74116891
84Reticulocytopenia (HP:0001896)1.73787893
85Abnormality of cells of the lymphoid lineage (HP:0012140)1.72614923
86Unsteady gait (HP:0002317)1.70394722
87Amyotrophic lateral sclerosis (HP:0007354)1.69375520
88Pancreatic cysts (HP:0001737)1.69356813
89Chest pain (HP:0100749)1.68618648
90Hyperglycinuria (HP:0003108)1.67943276
91Abnormal lung lobation (HP:0002101)1.67852119
92Nasolacrimal duct obstruction (HP:0000579)1.66754208
9311 pairs of ribs (HP:0000878)1.66349285
94Abnormality of T cell number (HP:0011839)1.65388194
95Chronic sinusitis (HP:0011109)1.63931975
96Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.62823498
97Ureteral obstruction (HP:0006000)1.62513758
98Lymphopenia (HP:0001888)1.62168425
99Attenuation of retinal blood vessels (HP:0007843)1.60673971
100Atrophy/Degeneration involving motor neurons (HP:0007373)1.60292424

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR6.74918410
2BCKDK5.23061554
3TESK24.79758010
4VRK23.74239641
5TXK3.42733086
6MAP3K102.84131743
7SCYL22.54351413
8MAP4K12.17496700
9VRK12.10794813
10FES2.10705561
11PIK3CG2.04356431
12BUB12.03673932
13MUSK2.02224428
14NUAK11.93486204
15DYRK31.68442589
16STK41.66631614
17MAPK151.63258217
18TLK11.41111232
19STK161.38155869
20GRK61.32559291
21UHMK11.31365426
22PIM21.23740946
23ZAP701.14923924
24IRAK21.13909181
25CHUK1.11960326
26SIK11.08885483
27ADRBK21.07861856
28GRK11.05027452
29IKBKB0.99750589
30INSRR0.93837737
31BRD40.91389345
32TNK20.87732885
33ITK0.86615059
34TAOK30.86039546
35PLK40.83859435
36BMX0.79318880
37PRPF4B0.79226292
38WNK30.78401330
39ZAK0.76700567
40FLT30.73485703
41PRKCQ0.73417002
42TBK10.72499281
43NTRK30.71081481
44AURKB0.70817103
45IRAK40.68829043
46MAPK130.66685671
47IKBKE0.66127857
48TRIM280.64464028
49DYRK1B0.63985867
50BRSK10.63073735
51RPS6KA50.62860981
52AURKA0.62007854
53LCK0.61443329
54BLK0.60920431
55TESK10.59698632
56LIMK10.59651594
57PIM10.58527614
58DYRK20.58032191
59CSK0.57773268
60CDK120.56777073
61MKNK20.56044847
62ATR0.54551977
63LYN0.54227327
64SYK0.53739584
65BRAF0.53345405
66NEK20.52644907
67AKT30.52180981
68MAPK40.51132990
69CCNB10.49835988
70CSF1R0.49493512
71HIPK20.48729490
72PAK10.46035966
73PASK0.45318135
74MAPK30.43364518
75SIK30.42290931
76MAP4K20.42118564
77LRRK20.40574379
78MAPK70.39029155
79JAK30.36924124
80CAMK10.35275236
81SIK20.33841155
82CSNK2A10.33133431
83CSNK1G30.30682156
84PRKCG0.30262231
85MAP3K70.29191001
86CDC42BPA0.29035795
87CDK20.28957478
88BTK0.28855327
89PRKD10.28806267
90CSNK2A20.28612558
91PRKAA10.27670877
92MARK10.26787794
93MAPKAPK20.26598223
94CSNK1G20.25766038
95DYRK1A0.25493680
96PRKCA0.25017643
97MAP3K80.24986809
98DMPK0.24648481
99CAMK40.24240149
100CDC70.23792161

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.81960156
2Ribosome_Homo sapiens_hsa030104.10873121
3Oxidative phosphorylation_Homo sapiens_hsa001903.97406614
4Parkinsons disease_Homo sapiens_hsa050123.20159866
5Proteasome_Homo sapiens_hsa030502.89864731
6Phenylalanine metabolism_Homo sapiens_hsa003602.81411540
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.64103243
8Graft-versus-host disease_Homo sapiens_hsa053322.34159944
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.34035855
10Huntingtons disease_Homo sapiens_hsa050162.19838716
11RNA polymerase_Homo sapiens_hsa030202.17826374
12Allograft rejection_Homo sapiens_hsa053302.06531107
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.05185704
14Autoimmune thyroid disease_Homo sapiens_hsa053202.01405698
15Alzheimers disease_Homo sapiens_hsa050101.92604226
16Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.82594277
17Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.68960193
18Antigen processing and presentation_Homo sapiens_hsa046121.66793255
19Spliceosome_Homo sapiens_hsa030401.60868764
20Type I diabetes mellitus_Homo sapiens_hsa049401.58593727
21Intestinal immune network for IgA production_Homo sapiens_hsa046721.56178535
22Tyrosine metabolism_Homo sapiens_hsa003501.49565069
23Hematopoietic cell lineage_Homo sapiens_hsa046401.37418632
24Sulfur relay system_Homo sapiens_hsa041221.35546149
25T cell receptor signaling pathway_Homo sapiens_hsa046601.34315970
26Systemic lupus erythematosus_Homo sapiens_hsa053221.30631112
27Fatty acid elongation_Homo sapiens_hsa000621.27662181
28Homologous recombination_Homo sapiens_hsa034401.25558534
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.21742042
30Salmonella infection_Homo sapiens_hsa051321.19027186
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.17985238
32Other glycan degradation_Homo sapiens_hsa005111.17949202
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16167340
34Collecting duct acid secretion_Homo sapiens_hsa049661.11502119
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08698135
36Rheumatoid arthritis_Homo sapiens_hsa053231.08386656
37Vitamin digestion and absorption_Homo sapiens_hsa049771.07399110
38Basal cell carcinoma_Homo sapiens_hsa052171.07006326
39Herpes simplex infection_Homo sapiens_hsa051681.06934492
40Cardiac muscle contraction_Homo sapiens_hsa042601.06431920
41Pyrimidine metabolism_Homo sapiens_hsa002401.05557397
42Asthma_Homo sapiens_hsa053101.05170465
43Tryptophan metabolism_Homo sapiens_hsa003801.00367022
44Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.00060461
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98284453
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.96571407
47Base excision repair_Homo sapiens_hsa034100.93365205
48RNA transport_Homo sapiens_hsa030130.91502541
49Basal transcription factors_Homo sapiens_hsa030220.85825393
50Viral myocarditis_Homo sapiens_hsa054160.83234902
51Alcoholism_Homo sapiens_hsa050340.82913495
52Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.79999731
53Measles_Homo sapiens_hsa051620.77000428
54Shigellosis_Homo sapiens_hsa051310.76387685
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73740719
56ABC transporters_Homo sapiens_hsa020100.72470591
57Purine metabolism_Homo sapiens_hsa002300.71940410
58Epstein-Barr virus infection_Homo sapiens_hsa051690.68938453
59DNA replication_Homo sapiens_hsa030300.66233880
60Phagosome_Homo sapiens_hsa041450.64450207
61Butanoate metabolism_Homo sapiens_hsa006500.61637841
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60667881
63Biosynthesis of amino acids_Homo sapiens_hsa012300.58430116
64Regulation of autophagy_Homo sapiens_hsa041400.57783371
65Phototransduction_Homo sapiens_hsa047440.55258251
66Hedgehog signaling pathway_Homo sapiens_hsa043400.54479146
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.52064282
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51687807
69Nitrogen metabolism_Homo sapiens_hsa009100.49825415
70Leishmaniasis_Homo sapiens_hsa051400.49124096
71RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48952101
72Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.47111291
73Galactose metabolism_Homo sapiens_hsa000520.40538023
74Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40363663
75Linoleic acid metabolism_Homo sapiens_hsa005910.39227517
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38089390
77Metabolic pathways_Homo sapiens_hsa011000.37814513
78Nucleotide excision repair_Homo sapiens_hsa034200.37704875
79Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.37674607
80Histidine metabolism_Homo sapiens_hsa003400.37532871
81Caffeine metabolism_Homo sapiens_hsa002320.36084463
82HTLV-I infection_Homo sapiens_hsa051660.35765406
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35620424
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34897819
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.34350018
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29913213
87Sulfur metabolism_Homo sapiens_hsa009200.29845943
88RNA degradation_Homo sapiens_hsa030180.28627869
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28516271
90Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.27308791
91Synaptic vesicle cycle_Homo sapiens_hsa047210.27240758
92Olfactory transduction_Homo sapiens_hsa047400.25786658
93Apoptosis_Homo sapiens_hsa042100.24930937
94Fat digestion and absorption_Homo sapiens_hsa049750.23117750
95Peroxisome_Homo sapiens_hsa041460.22941025
96beta-Alanine metabolism_Homo sapiens_hsa004100.21833518
97Fanconi anemia pathway_Homo sapiens_hsa034600.19488354
98Pyruvate metabolism_Homo sapiens_hsa006200.19043467
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.19004304
100Amphetamine addiction_Homo sapiens_hsa050310.14943381

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »