PYGO2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)4.60914315
2COPI coating of Golgi vesicle (GO:0048205)4.60914315
3heterochromatin organization (GO:0070828)4.24729828
4pre-miRNA processing (GO:0031054)3.74645947
5proline biosynthetic process (GO:0006561)3.67825502
6retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.60363087
7protein retention in ER lumen (GO:0006621)3.60351207
8mitotic chromosome condensation (GO:0007076)3.55729659
9* regulation of mammary gland epithelial cell proliferation (GO:0033599)3.46848052
10activation of Rac GTPase activity (GO:0032863)3.46286114
11spliceosomal tri-snRNP complex assembly (GO:0000244)3.45910217
12peptidyl-arginine methylation (GO:0018216)3.39909594
13peptidyl-arginine N-methylation (GO:0035246)3.39909594
14regulation of translational fidelity (GO:0006450)3.39390076
15maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.35154135
16embryonic process involved in female pregnancy (GO:0060136)3.30205634
17peptidyl-arginine omega-N-methylation (GO:0035247)3.29178742
18regulation of sister chromatid cohesion (GO:0007063)3.25124514
19regulation of hippo signaling (GO:0035330)3.24883913
20regulation of gene silencing by RNA (GO:0060966)3.24300979
21regulation of posttranscriptional gene silencing (GO:0060147)3.24300979
22regulation of gene silencing by miRNA (GO:0060964)3.24300979
23pentose-phosphate shunt (GO:0006098)3.22929246
24negative regulation of cell size (GO:0045792)3.22143585
25protein localization to kinetochore (GO:0034501)3.22096243
26establishment of apical/basal cell polarity (GO:0035089)3.21511364
27formation of translation preinitiation complex (GO:0001731)3.18612059
28ribosomal small subunit biogenesis (GO:0042274)3.15741875
29protein localization to endosome (GO:0036010)3.14087431
30DNA unwinding involved in DNA replication (GO:0006268)3.12095737
31positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.11530738
32dosage compensation (GO:0007549)3.09890151
33mRNA stabilization (GO:0048255)3.08607897
34RNA stabilization (GO:0043489)3.08607897
35modulation by virus of host process (GO:0019054)3.08017025
36positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.07736155
37positive regulation of Cdc42 GTPase activity (GO:0043089)3.06537305
38regulation of histone H3-K27 methylation (GO:0061085)3.00590100
39negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.96898562
40polarized epithelial cell differentiation (GO:0030859)2.96539050
413-UTR-mediated mRNA stabilization (GO:0070935)2.96506376
42positive regulation of histone deacetylation (GO:0031065)2.91401247
43negative regulation of histone methylation (GO:0031061)2.89286974
44regulation of protein heterodimerization activity (GO:0043497)2.87466063
45histone H2A monoubiquitination (GO:0035518)2.85793417
46apoptotic process involved in morphogenesis (GO:0060561)2.84908953
47establishment or maintenance of monopolar cell polarity (GO:0061339)2.84823799
48establishment of monopolar cell polarity (GO:0061162)2.84823799
49intracellular estrogen receptor signaling pathway (GO:0030520)2.84006972
50planar cell polarity pathway involved in neural tube closure (GO:0090179)2.83402118
51folic acid-containing compound biosynthetic process (GO:0009396)2.82339157
52antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.81605240
53regulation of NFAT protein import into nucleus (GO:0051532)2.81443266
54regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.81200611
55modulation by symbiont of host cellular process (GO:0044068)2.80445819
56glucose catabolic process (GO:0006007)2.80207498
57thymic T cell selection (GO:0045061)2.76631213
58maternal placenta development (GO:0001893)2.76548946
59snRNA metabolic process (GO:0016073)2.76251246
60regulation of nucleobase-containing compound transport (GO:0032239)2.75421335
61positive regulation of protein import into nucleus, translocation (GO:0033160)2.75233088
62mitotic nuclear envelope disassembly (GO:0007077)2.74335268
63cellular response to virus (GO:0098586)2.74220045
64modulation by virus of host morphology or physiology (GO:0019048)2.74082576
65negative regulation of fatty acid transport (GO:2000192)2.73361373
66regulation of RNA export from nucleus (GO:0046831)2.72656471
67histone H4 deacetylation (GO:0070933)2.70822864
68viral transcription (GO:0019083)2.70333548
69cellular response to epidermal growth factor stimulus (GO:0071364)2.70156935
70chromatin assembly (GO:0031497)2.69613589
71nuclear envelope disassembly (GO:0051081)2.69423934
72membrane disassembly (GO:0030397)2.69423934
73positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.67605842
74mitotic G1 DNA damage checkpoint (GO:0031571)2.66996513
75NADPH regeneration (GO:0006740)2.66960158
76regulation of early endosome to late endosome transport (GO:2000641)2.65833705
77cellular response to interleukin-4 (GO:0071353)2.65825919
78glucocorticoid receptor signaling pathway (GO:0042921)2.65463521
79folic acid metabolic process (GO:0046655)2.63901926
80protein export from nucleus (GO:0006611)2.63648200
81* regulation of chromatin binding (GO:0035561)2.63179358
82adherens junction assembly (GO:0034333)2.62546988
83regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.62256684
84regulation of defense response to virus by virus (GO:0050690)2.62252797
85regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.61955058
86DNA replication-dependent nucleosome organization (GO:0034723)2.61598872
87DNA replication-dependent nucleosome assembly (GO:0006335)2.61598872
88antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.61582376
89nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.60998780
90regulation of glucose import in response to insulin stimulus (GO:2001273)2.60053792
91translational termination (GO:0006415)2.58890825
92negative regulation of RNA splicing (GO:0033119)2.58291308
93regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.58003413
94regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.55492233
95positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.55492233
96protein localization to chromosome, centromeric region (GO:0071459)2.55364088
97negative regulation of viral release from host cell (GO:1902187)2.54985581
98regulation of translational termination (GO:0006449)2.54846231
99antigen processing and presentation of endogenous antigen (GO:0019883)2.54716609
100cell-cell junction maintenance (GO:0045217)2.52033198
101epithelial cell differentiation involved in prostate gland development (GO:0060742)2.51818903
102regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.50620227
103positive regulation of protein deacetylation (GO:0090312)2.49834069
104hippo signaling (GO:0035329)2.49326287
105positive regulation of nuclease activity (GO:0032075)2.48259848
106activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.47680843
107apoptotic cell clearance (GO:0043277)2.46578357
108negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.46491155
109stress fiber assembly (GO:0043149)2.46413794
110positive regulation of SMAD protein import into nucleus (GO:0060391)2.46051721
111regulation of ARF protein signal transduction (GO:0032012)2.45783532
112nuclear pore complex assembly (GO:0051292)2.45444567
113peptidyl-tyrosine autophosphorylation (GO:0038083)2.45432019
114negative regulation of myotube differentiation (GO:0010832)2.45287146
115trophectodermal cell differentiation (GO:0001829)2.45067669
116regulation of SMAD protein import into nucleus (GO:0060390)2.43252186
117negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.42537073
118negative regulation of cell killing (GO:0031342)2.42537073
119protein targeting to plasma membrane (GO:0072661)2.42141801
120nuclear envelope organization (GO:0006998)2.41634781
121response to laminar fluid shear stress (GO:0034616)2.41629795
122signal complex assembly (GO:0007172)2.41448173
123paraxial mesoderm development (GO:0048339)2.40520167
124negative regulation of necroptotic process (GO:0060546)2.40253580
125cytoskeletal anchoring at plasma membrane (GO:0007016)2.40100929
126mitotic G1/S transition checkpoint (GO:0044819)2.38224115
127negative regulation of mRNA processing (GO:0050686)2.38136342
128negative regulation of erythrocyte differentiation (GO:0045647)2.37951824
129translational elongation (GO:0006414)2.37680281
130response to interleukin-4 (GO:0070670)2.37625007
131maturation of SSU-rRNA (GO:0030490)2.37403020
132intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.37316837
133histone arginine methylation (GO:0034969)2.37215386
134nuclear pore organization (GO:0006999)2.36371371
135regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.35441009
136regulation of nuclease activity (GO:0032069)2.34648206
137apoptotic process involved in development (GO:1902742)2.34215445
138response to epidermal growth factor (GO:0070849)2.34158024
139embryonic camera-type eye development (GO:0031076)2.33689215
140translational initiation (GO:0006413)2.33237603
141negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.32532920
142focal adhesion assembly (GO:0048041)2.31694096
143cell-substrate adherens junction assembly (GO:0007045)2.31694096
144glucose 6-phosphate metabolic process (GO:0051156)2.31259947
145peptidyl-lysine dimethylation (GO:0018027)2.30550475
146branching involved in salivary gland morphogenesis (GO:0060445)2.29014890
147nodal signaling pathway (GO:0038092)2.28214562
148proline metabolic process (GO:0006560)2.28208584
149positive regulation of gene expression, epigenetic (GO:0045815)2.28117825
150regulation of integrin activation (GO:0033623)2.27472985
151protein complex localization (GO:0031503)2.27468306
152cell-substrate junction assembly (GO:0007044)2.27043454
153mannose metabolic process (GO:0006013)2.26907752
154G1 DNA damage checkpoint (GO:0044783)2.26368006
155post-embryonic morphogenesis (GO:0009886)2.25961277
156labyrinthine layer blood vessel development (GO:0060716)2.25145742
157skin morphogenesis (GO:0043589)2.24593213
158positive regulation of chromosome segregation (GO:0051984)2.24361805
159peptidyl-arginine modification (GO:0018195)2.24211792
160corticosteroid receptor signaling pathway (GO:0031958)2.24143826
161sister chromatid segregation (GO:0000819)2.23964921
162mitotic sister chromatid segregation (GO:0000070)2.19950240
163protein-DNA complex disassembly (GO:0032986)2.19879239
164nucleosome disassembly (GO:0006337)2.19879239
165morphogenesis of an endothelium (GO:0003159)2.19777501
166endothelial tube morphogenesis (GO:0061154)2.19777501

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human3.97022516
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.82420793
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.50525720
4MYC_22102868_ChIP-Seq_BL_Human3.15108014
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.01071931
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.85359492
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.45575430
8* VDR_21846776_ChIP-Seq_THP-1_Human2.32119657
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.26036908
10ELK3_25401928_ChIP-Seq_HUVEC_Human2.21165602
11ZNF263_19887448_ChIP-Seq_K562_Human2.18911577
12* TCF7_22412390_ChIP-Seq_EML_Mouse2.12996097
13* KDM2B_26808549_Chip-Seq_DND41_Human2.05963934
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.05528046
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.03942819
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.01055681
17KDM2B_26808549_Chip-Seq_SUP-B15_Human2.00667680
18ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.96940164
19STAT6_21828071_ChIP-Seq_BEAS2B_Human1.92421177
20KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.91529475
21MYC_19079543_ChIP-ChIP_MESCs_Mouse1.90287321
22TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84016417
23ZFP281_18757296_ChIP-ChIP_E14_Mouse1.79543758
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.79540693
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72315816
26* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.69209582
27POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.67003326
28LXR_22292898_ChIP-Seq_THP-1_Human1.64852231
29* RACK7_27058665_Chip-Seq_MCF-7_Human1.62311320
30* MAF_26560356_Chip-Seq_TH1_Human1.60351493
31KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.59985952
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.59363170
33* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.57426910
34ZFP281_27345836_Chip-Seq_ESCs_Mouse1.55422505
35ATF3_27146783_Chip-Seq_COLON_Human1.55312365
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53612122
37XRN2_22483619_ChIP-Seq_HELA_Human1.53195015
38P68_20966046_ChIP-Seq_HELA_Human1.52283417
39* TET1_21451524_ChIP-Seq_MESCs_Mouse1.52002680
40DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.51268486
41UTX_26944678_Chip-Seq_JUKART_Human1.50641633
42SRY_22984422_ChIP-ChIP_TESTIS_Rat1.50141618
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.49533756
44SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.47501349
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46412288
46* SA1_27219007_Chip-Seq_ERYTHROID_Human1.45624707
47NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.43857824
48CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.41891109
49* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.41840562
50KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.41754842
51KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.41754842
52KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.41754842
53KDM2B_26808549_Chip-Seq_JURKAT_Human1.41028495
54KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.40269835
55* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38455862
56CLOCK_20551151_ChIP-Seq_293T_Human1.37980135
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.36387207
58ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35394853
59SMC4_20622854_ChIP-Seq_HELA_Human1.31774916
60NCOR1_26117541_ChIP-Seq_K562_Human1.31019359
61HIF1A_21447827_ChIP-Seq_MCF-7_Human1.30545494
62* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.30453634
63EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.29674296
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.28147445
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.27190134
66E2F4_17652178_ChIP-ChIP_JURKAT_Human1.27159840
67EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25713532
68TCF3_18692474_ChIP-Seq_MEFs_Mouse1.25011835
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24026473
70KDM2B_26808549_Chip-Seq_K562_Human1.23554003
71* VDR_24763502_ChIP-Seq_THP-1_Human1.23467957
72CIITA_25753668_ChIP-Seq_RAJI_Human1.20981937
73MYC_19030024_ChIP-ChIP_MESCs_Mouse1.20897453
74UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.20736951
75NANOG_21062744_ChIP-ChIP_HESCs_Human1.20611215
76WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.18529936
77ERG_21242973_ChIP-ChIP_JURKAT_Human1.18306910
78E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.17449639
79AR_21909140_ChIP-Seq_LNCAP_Human1.16979217
80BRD4_27068464_Chip-Seq_AML-cells_Mouse1.16520812
81NELFA_20434984_ChIP-Seq_ESCs_Mouse1.15543959
82* MAF_26560356_Chip-Seq_TH2_Human1.15213484
83SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.15198603
84CREB1_26743006_Chip-Seq_LNCaP_Human1.15177537
85THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15048541
86SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.14629816
87SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.14397365
88TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14085558
89GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13173927
90ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11630350
91CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.11514420
92MYC_18358816_ChIP-ChIP_MESCs_Mouse1.11510196
93SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11122180
94TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.10922584
95TP53_22127205_ChIP-Seq_IMR90_Human1.09494133
96TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09372802
97E2F1_21310950_ChIP-Seq_MCF-7_Human1.09161235
98ESR2_21235772_ChIP-Seq_MCF-7_Human1.07720042
99ELF1_20517297_ChIP-Seq_JURKAT_Human1.06495618
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.06417786
101CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.05189208
102SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05013248
103* CHD1_26751641_Chip-Seq_LNCaP_Human1.04484585
104BCOR_27268052_Chip-Seq_Bcells_Human1.03136183
105POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.03049079
106CTCF_27219007_Chip-Seq_ERYTHROID_Human1.02833186
107NANOG_18555785_ChIP-Seq_MESCs_Mouse1.02824802
108ZFX_18555785_ChIP-Seq_MESCs_Mouse1.02812463
109* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02698586
110RUNX1_22412390_ChIP-Seq_EML_Mouse1.01836206
111* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.01635756
112RUNX1_27514584_Chip-Seq_MCF-7_Human1.01412091
113PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99687674
114NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.99382394
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.99350614
116KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99132419
117MYB_26560356_Chip-Seq_TH1_Human0.99006736
118TFEB_21752829_ChIP-Seq_HELA_Human0.98631202
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.97555227
120SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97148363
121* KDM5A_27292631_Chip-Seq_BREAST_Human0.97117544
122DNAJC2_21179169_ChIP-ChIP_NT2_Human0.97089726
123* CTCF_21964334_Chip-Seq_Bcells_Human0.97066979
124TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96651005
125TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.96603222
126CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.96526580
127ETS1_21867929_ChIP-Seq_TH2_Mouse0.96206031
128STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.95685313
129OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95362427
130MYB_21317192_ChIP-Seq_ERMYB_Mouse0.93264394

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.64601332
2MP0005076_abnormal_cell_differentiation3.33762924
3MP0010030_abnormal_orbit_morphology3.21644431
4MP0010352_gastrointestinal_tract_polyps3.13569692
5MP0005451_abnormal_body_composition2.99364820
6MP0004185_abnormal_adipocyte_glucose2.72134542
7MP0008260_abnormal_autophagy2.53731443
8MP0009278_abnormal_bone_marrow2.43597722
9MP0000537_abnormal_urethra_morphology2.26632809
10MP0001849_ear_inflammation2.23519868
11MP0003566_abnormal_cell_adhesion2.18180703
12MP0003693_abnormal_embryo_hatching2.09410362
13MP0005058_abnormal_lysosome_morphology2.02440740
14MP0001346_abnormal_lacrimal_gland1.96458515
15MP0005409_darkened_coat_color1.94181712
16MP0005623_abnormal_meninges_morphology1.93080111
17MP0010234_abnormal_vibrissa_follicle1.90955732
18MP0003303_peritoneal_inflammation1.90936943
19MP0004957_abnormal_blastocyst_morpholog1.87106142
20MP0003111_abnormal_nucleus_morphology1.85271964
21MP0004808_abnormal_hematopoietic_stem1.84166193
22MP0000733_abnormal_muscle_development1.83806743
23MP0003123_paternal_imprinting1.81237074
24MP0000678_abnormal_parathyroid_gland1.78668123
25MP0009053_abnormal_anal_canal1.72126262
26MP0003763_abnormal_thymus_physiology1.70146895
27MP0002877_abnormal_melanocyte_morpholog1.67753806
28MP0008438_abnormal_cutaneous_collagen1.63527194
29MP0006054_spinal_hemorrhage1.63273464
30MP0001730_embryonic_growth_arrest1.63265784
31MP0000350_abnormal_cell_proliferation1.62840234
32MP0003300_gastrointestinal_ulcer1.58761250
33MP0002009_preneoplasia1.58679135
34MP0003077_abnormal_cell_cycle1.58660190
35MP0005023_abnormal_wound_healing1.56771533
36MP0003279_aneurysm1.56652396
37MP0004233_abnormal_muscle_weight1.50849473
38MP0005666_abnormal_adipose_tissue1.50245816
39* MP0004197_abnormal_fetal_growth/weight/1.49999143
40MP0002396_abnormal_hematopoietic_system1.49296200
41MP0000858_altered_metastatic_potential1.47650327
42MP0001545_abnormal_hematopoietic_system1.46329288
43MP0005397_hematopoietic_system_phenotyp1.46329288
44MP0010307_abnormal_tumor_latency1.42245250
45MP0004381_abnormal_hair_follicle1.38056738
46MP0003191_abnormal_cellular_cholesterol1.37294325
47MP0000566_synostosis1.36735494
48MP0002085_abnormal_embryonic_tissue1.36526348
49MP0002086_abnormal_extraembryonic_tissu1.34954594
50MP0002084_abnormal_developmental_patter1.34451253
51MP0009333_abnormal_splenocyte_physiolog1.32566397
52MP0001672_abnormal_embryogenesis/_devel1.29787190
53MP0005380_embryogenesis_phenotype1.29787190
54MP0003119_abnormal_digestive_system1.29673284
55MP0009379_abnormal_foot_pigmentation1.29567904
56MP0008057_abnormal_DNA_replication1.27842689
57MP0001697_abnormal_embryo_size1.27368569
58MP0000685_abnormal_immune_system1.20634516
59MP0003091_abnormal_cell_migration1.19370894
60MP0000681_abnormal_thyroid_gland1.18861082
61MP0002088_abnormal_embryonic_growth/wei1.17330140
62* MP0003942_abnormal_urinary_system1.16994252
63MP0003984_embryonic_growth_retardation1.16661140
64MP0005375_adipose_tissue_phenotype1.15542068
65MP0002080_prenatal_lethality1.15188290
66MP0000490_abnormal_crypts_of1.14953392
67* MP0009672_abnormal_birth_weight1.14318218
68MP0003890_abnormal_embryonic-extraembry1.14037465
69MP0001873_stomach_inflammation1.13507324
70MP0002653_abnormal_ependyma_morphology1.12798480
71MP0005083_abnormal_biliary_tract1.11598402
72MP0004947_skin_inflammation1.11569034
73* MP0003115_abnormal_respiratory_system1.10763749
74MP0000428_abnormal_craniofacial_morphol1.10362191
75MP0000003_abnormal_adipose_tissue1.09827382
76MP0008007_abnormal_cellular_replicative1.09552532
77MP0002166_altered_tumor_susceptibility1.07936766
78MP0001348_abnormal_lacrimal_gland1.07198633
79MP0010094_abnormal_chromosome_stability1.07123226
80MP0003329_amyloid_beta_deposits1.05868268
81MP0002092_abnormal_eye_morphology1.05855712
82MP0003121_genomic_imprinting1.05342518
83MP0002925_abnormal_cardiovascular_devel1.04458655
84MP0003283_abnormal_digestive_organ1.03581788
85MP0004264_abnormal_extraembryonic_tissu1.00725646
86* MP0000534_abnormal_ureter_morphology0.99036678
87MP0002932_abnormal_joint_morphology0.98940223
88MP0003448_altered_tumor_morphology0.98136358
89MP0005257_abnormal_intraocular_pressure0.98037715
90MP0002796_impaired_skin_barrier0.97890531
91MP0002822_catalepsy0.96969596
92MP0003453_abnormal_keratinocyte_physiol0.96326773
93MP0010630_abnormal_cardiac_muscle0.95739446
94MP0002234_abnormal_pharynx_morphology0.94393499
95MP0002132_abnormal_respiratory_system0.94356322
96MP0003866_abnormal_defecation0.93718669
97MP0002019_abnormal_tumor_incidence0.93497712
98MP0009931_abnormal_skin_appearance0.93139556
99MP0005501_abnormal_skin_physiology0.93129011
100MP0003436_decreased_susceptibility_to0.92749067
101MP0008961_abnormal_basal_metabolism0.91912655
102MP0001915_intracranial_hemorrhage0.90806397
103MP0005275_abnormal_skin_tensile0.89862851
104MP0002060_abnormal_skin_morphology0.88513236
105MP0008770_decreased_survivor_rate0.87129660
106MP0004858_abnormal_nervous_system0.86943935
107MP0002398_abnormal_bone_marrow0.86929382
108MP0000703_abnormal_thymus_morphology0.86845523
109MP0009840_abnormal_foam_cell0.86650970
110MP0002111_abnormal_tail_morphology0.85100412
111MP0003122_maternal_imprinting0.84874996
112MP0005508_abnormal_skeleton_morphology0.84741532
113MP0002429_abnormal_blood_cell0.84539556
114MP0003385_abnormal_body_wall0.83315333
115MP0000313_abnormal_cell_death0.83270798
116MP0003172_abnormal_lysosome_physiology0.82807629
117MP0000049_abnormal_middle_ear0.82739110
118MP0002282_abnormal_trachea_morphology0.80554641
119MP0003315_abnormal_perineum_morphology0.80296496
120MP0005621_abnormal_cell_physiology0.79347080
121* MP0000477_abnormal_intestine_morphology0.79123606
122MP0003935_abnormal_craniofacial_develop0.77010657
123MP0000716_abnormal_immune_system0.76831330
124MP0001293_anophthalmia0.76740861
125* MP0002697_abnormal_eye_size0.76691405
126MP0002249_abnormal_larynx_morphology0.76539421
127MP0010368_abnormal_lymphatic_system0.76295148
128MP0002405_respiratory_system_inflammati0.76011816
129MP0002098_abnormal_vibrissa_morphology0.75814896
130MP0008932_abnormal_embryonic_tissue0.75459859
131MP0002089_abnormal_postnatal_growth/wei0.75318827
132* MP0009703_decreased_birth_body0.74117575
133MP0002722_abnormal_immune_system0.74040887
134MP0000767_abnormal_smooth_muscle0.74040810
135MP0005025_abnormal_response_to0.73946382
136MP0000747_muscle_weakness0.73016434
137MP0005384_cellular_phenotype0.71663033
138MP0001851_eye_inflammation0.70421910
139MP0001819_abnormal_immune_cell0.69575452
140MP0002420_abnormal_adaptive_immunity0.69478850
141MP0000759_abnormal_skeletal_muscle0.69446993
142MP0001216_abnormal_epidermal_layer0.68711409

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)3.38256059
2Premature rupture of membranes (HP:0001788)3.36582065
3Protrusio acetabuli (HP:0003179)3.35550457
4Shallow orbits (HP:0000586)3.19541854
5Hyperacusis (HP:0010780)3.07849887
6Renal duplication (HP:0000075)2.82182321
7Ulnar bowing (HP:0003031)2.79287340
8Broad face (HP:0000283)2.75205213
9Long palpebral fissure (HP:0000637)2.69915331
10Upper limb amyotrophy (HP:0009129)2.62398074
11Distal upper limb amyotrophy (HP:0007149)2.62398074
12Hand muscle atrophy (HP:0009130)2.62101501
13Dilatation of the ascending aorta (HP:0005111)2.60086177
14Genu recurvatum (HP:0002816)2.49571246
15Short 4th metacarpal (HP:0010044)2.47187488
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.47187488
17Asymmetry of the thorax (HP:0001555)2.43933233
18Obstructive sleep apnea (HP:0002870)2.43047735
19Centrally nucleated skeletal muscle fibers (HP:0003687)2.38816894
20Eczematoid dermatitis (HP:0000976)2.38381492
21Vertebral compression fractures (HP:0002953)2.37085352
22Bladder diverticulum (HP:0000015)2.35788721
23Abnormality of the thoracic spine (HP:0100711)2.34353855
24Selective tooth agenesis (HP:0001592)2.33451734
25Growth hormone excess (HP:0000845)2.30878847
26Metaphyseal cupping (HP:0003021)2.28648804
27Disproportionate tall stature (HP:0001519)2.28611084
28Deviation of the hallux (HP:0010051)2.27102835
29Abnormality of the distal phalanges of the toes (HP:0010182)2.27061417
30Hypertensive crisis (HP:0100735)2.26587479
31Hallux valgus (HP:0001822)2.23255522
32Abnormality of the fingertips (HP:0001211)2.22766066
33Bowel diverticulosis (HP:0005222)2.21740248
34Distal lower limb amyotrophy (HP:0008944)2.20058500
35Mitral valve prolapse (HP:0001634)2.18490861
36Increased IgE level (HP:0003212)2.13878575
37Hypercortisolism (HP:0001578)2.12993677
38Short 5th finger (HP:0009237)2.12648931
39Broad distal phalanx of finger (HP:0009836)2.11766689
40Ankle contracture (HP:0006466)2.11068624
41Abnormal gallbladder physiology (HP:0012438)2.09832424
42Cholecystitis (HP:0001082)2.09832424
43Subacute progressive viral hepatitis (HP:0006572)2.09447879
44Seborrheic dermatitis (HP:0001051)2.08684987
45Ependymoma (HP:0002888)2.07781608
46Increased density of long bones (HP:0006392)2.06943591
47Peritonitis (HP:0002586)2.06236049
48Thoracic kyphosis (HP:0002942)2.04777549
49Reticulocytosis (HP:0001923)2.03049686
50Aortic aneurysm (HP:0004942)2.01345734
51Abnormality of the calcaneus (HP:0008364)2.00862455
52Difficulty climbing stairs (HP:0003551)2.00199276
53Osteolytic defects of the phalanges of the hand (HP:0009771)1.99998686
54Osteolytic defects of the hand bones (HP:0009699)1.99998686
55Distal lower limb muscle weakness (HP:0009053)1.99485835
56Colitis (HP:0002583)1.99408534
57Urethral obstruction (HP:0000796)1.98869106
58Broad palm (HP:0001169)1.98834041
59Missing ribs (HP:0000921)1.97910908
60Bowed forearm bones (HP:0003956)1.97765100
61Bowing of the arm (HP:0006488)1.97765100
62Hyperparathyroidism (HP:0000843)1.96502835
63Abnormality of the phalanges of the hallux (HP:0010057)1.95810105
64Atrophic scars (HP:0001075)1.94729909
65Deep palmar crease (HP:0006191)1.94049540
66High pitched voice (HP:0001620)1.93971469
67Flat acetabular roof (HP:0003180)1.93706493
68Ragged-red muscle fibers (HP:0003200)1.93441919
69Gastrointestinal inflammation (HP:0004386)1.93315253
70Segmental peripheral demyelination/remyelination (HP:0003481)1.92501211
71Truncus arteriosus (HP:0001660)1.92258808
72Abnormality of the astrocytes (HP:0100707)1.91350570
73Astrocytoma (HP:0009592)1.91350570
74Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.91098771
75Flattened epiphyses (HP:0003071)1.90574025
76Progressive muscle weakness (HP:0003323)1.89330441
77Germ cell neoplasia (HP:0100728)1.88925498
78Achilles tendon contracture (HP:0001771)1.87924209
79Abnormality of the 4th metacarpal (HP:0010012)1.87892518
80Sparse lateral eyebrow (HP:0005338)1.87843071
81Hemorrhage of the eye (HP:0011885)1.86865752
82Cervical subluxation (HP:0003308)1.86690364
83Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.86673764
84Short 1st metacarpal (HP:0010034)1.86673764
85Myopathic facies (HP:0002058)1.85870870
86Bowel incontinence (HP:0002607)1.85352760
87Gastrointestinal carcinoma (HP:0002672)1.84706918
88Malignant gastrointestinal tract tumors (HP:0006749)1.84706918
89Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.84058107
90Broad thumb (HP:0011304)1.82728430
91Overriding aorta (HP:0002623)1.82700868
92Partial duplication of thumb phalanx (HP:0009944)1.82047693
93Abnormality of oral frenula (HP:0000190)1.81320999
94Radial bowing (HP:0002986)1.80966954
95Vertebral hypoplasia (HP:0008417)1.80305653
96Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.80305653
97Patellar dislocation (HP:0002999)1.78883067
98Increased connective tissue (HP:0009025)1.77497878
99Turricephaly (HP:0000262)1.76065184
100Septate vagina (HP:0001153)1.76047830
101Persistence of primary teeth (HP:0006335)1.75373763
102Syringomyelia (HP:0003396)1.75315588
103Spinal cord lesions (HP:0100561)1.75315588
104Aneurysm (HP:0002617)1.75030347
105Abnormality of the acetabulum (HP:0003170)1.74254883
106Insomnia (HP:0100785)1.73356304
107Basal cell carcinoma (HP:0002671)1.72308993
108Deviation of the thumb (HP:0009603)1.71793138
109Skin tags (HP:0010609)1.71125271
110Trismus (HP:0000211)1.70966379
111Pointed chin (HP:0000307)1.70679386
112Testicular atrophy (HP:0000029)1.69456522
113Aortic dissection (HP:0002647)1.69302709
114Abnormal large intestine physiology (HP:0012700)1.69169136
115Polygenic inheritance (HP:0010982)1.69074575
116Short middle phalanx of the 5th finger (HP:0004220)1.68762020
117Thin bony cortex (HP:0002753)1.68558602
118Cellulitis (HP:0100658)1.68538945
119Hyperthyroidism (HP:0000836)1.67334630
120Pelvic girdle muscle weakness (HP:0003749)1.67175449
121Thin ribs (HP:0000883)1.66536019
122Abnormal ossification of hand bones (HP:0005921)1.66218324
123Arnold-Chiari malformation (HP:0002308)1.66203662
124Bicuspid aortic valve (HP:0001647)1.66184085
125Annular pancreas (HP:0001734)1.65888085
126Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.65467915
127Mildly elevated creatine phosphokinase (HP:0008180)1.63931080
128Premature skin wrinkling (HP:0100678)1.63759654
129Abnormality of reticulocytes (HP:0004312)1.63597276
130Back pain (HP:0003418)1.63566469
131Slow saccadic eye movements (HP:0000514)1.63445790
132Easy fatigability (HP:0003388)1.62224584
133Mitral regurgitation (HP:0001653)1.61995360
134Partial duplication of the phalanx of hand (HP:0009999)1.61327386
135Preauricular skin tag (HP:0000384)1.61032207
136Renovascular hypertension (HP:0100817)1.60528142
137Increased nuchal translucency (HP:0010880)1.60131852
138Progressive external ophthalmoplegia (HP:0000590)1.60071890
139Micronodular cirrhosis (HP:0001413)1.59853249
140Loss of speech (HP:0002371)1.59719267
141Abnormality of the salivary glands (HP:0010286)1.59635342
142Short phalanx of the thumb (HP:0009660)1.59532587
143Dislocated radial head (HP:0003083)1.59146908
144Congenital hip dislocation (HP:0001374)1.58691527
145Rectal prolapse (HP:0002035)1.57632213
146Colon cancer (HP:0003003)1.56783666
147Diminished motivation (HP:0000745)1.56711293
148Fused cervical vertebrae (HP:0002949)1.56418039
149Stridor (HP:0010307)1.56384767
150Broad phalanges of the hand (HP:0009768)1.55978886
151Abnormal foot bone ossification (HP:0010675)1.55892384
152Interstitial pulmonary disease (HP:0006530)1.54803751
153Supranuclear gaze palsy (HP:0000605)1.54404133
154Camptodactyly of toe (HP:0001836)1.54382537
155Abnormality of the lower motor neuron (HP:0002366)1.54336567
156Proximal placement of thumb (HP:0009623)1.53435451
157Ankyloglossia (HP:0010296)1.53330802
158Abnormality of the distal phalanx of the thumb (HP:0009617)1.52779399
159Fragile skin (HP:0001030)1.52742044
160Microvesicular hepatic steatosis (HP:0001414)1.52426431
161Long toe (HP:0010511)1.52360076
162Abnormality of the Achilles tendon (HP:0005109)1.52348880
163Flared metaphyses (HP:0003015)1.52174146
164Abnormality of carpal bone ossification (HP:0006257)1.51749394
165Wormian bones (HP:0002645)1.51402315
166Abnormal vertebral ossification (HP:0100569)1.51212566
167Biconcave vertebral bodies (HP:0004586)1.51146975
168Precocious puberty (HP:0000826)1.50799661
169Spinal cord compression (HP:0002176)1.50762872
170Neuronal loss in central nervous system (HP:0002529)1.49956496
171Pseudobulbar signs (HP:0002200)1.49848377
172Self-mutilation (HP:0000742)1.48910291

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.89564673
2TRIB33.82438738
3EEF2K3.63196519
4PRPF4B3.38983586
5MAP3K103.21394902
6CDK122.97731637
7PKN22.68021949
8ERN12.36432467
9EPHA22.09809456
10PDGFRA1.84358509
11SCYL21.82754979
12RIPK11.79378879
13STK101.75533994
14LRRK21.72918180
15ALK1.69279751
16TTN1.68906159
17LATS21.65569446
18FGFR41.62487362
19PAK41.60938037
20MAP4K11.60082015
21RPS6KA41.56069278
22BMX1.54944545
23RPS6KB21.52968790
24DDR21.52541030
25NEK21.52341003
26KSR21.51472632
27IRAK31.50899124
28MAP3K131.44670761
29PTK61.44120837
30RIPK41.42903899
31ARAF1.40874484
32SIK31.38973795
33ICK1.35021788
34MARK21.30387878
35SIK21.24767827
36MAP3K81.19194924
37GRK61.13580678
38EPHB21.13015134
39BUB11.12567760
40TAOK11.11799513
41DYRK31.09678297
42CDK71.09008560
43CDC71.08987005
44CDK61.08326495
45TAOK21.05676841
46PAK21.04999506
47HIPK21.03875147
48MAP2K31.02766605
49MTOR1.01854287
50DYRK1B1.01507453
51TYRO31.01071270
52PTK21.00597419
53PAK60.99538342
54FLT30.98298968
55TESK10.97145266
56CDK40.94955339
57TGFBR10.93768674
58IRAK20.92608058
59JAK30.91163906
60TESK20.88375215
61DMPK0.88071599
62PASK0.88015894
63TNK20.84950085
64MAP2K20.84929424
65MAP3K90.84612009
66MAP3K10.81576400
67IRAK40.80149532
68CAMKK10.79424557
69ILK0.78633759
70TYK20.78185645
71RAF10.77974364
72BRAF0.77906930
73ZAP700.76646928
74MAP3K110.75442199
75LATS10.74481027
76KSR10.74303983
77CAMK1D0.73809145
78MAPKAPK30.73614755
79MST1R0.72499191
80VRK20.71519374
81MET0.70143759
82PDGFRB0.69738538
83PDPK10.69006042
84RPS6KA20.68620033
85RPS6KA10.68151906
86NTRK10.67996493
87CLK10.66913260
88CSK0.66446755
89MAPK110.66439376
90PRKD30.64910838
91BRSK20.64020881
92EPHB10.63184037
93PAK10.62430100
94RPS6KL10.61397750
95RPS6KC10.61397750
96TTK0.61120382
97BRD40.60948029
98CDC42BPA0.57302118
99TBK10.56169746
100PIM10.55669352
101MAP3K70.54572915
102SIK10.54501775
103ACVR1B0.54039538
104CHEK10.53840350
105CDK90.53398052
106RPS6KA60.52624085
107MATK0.52508061
108STK30.51732915
109BTK0.48452125
110PIM20.47415643
111FGFR10.47099049
112PAK30.47069198
113TGFBR20.46214128
114STK380.45607901
115MAPKAPK20.44199744
116STK40.43874494
117HCK0.43537884
118PRKD20.43093707
119AURKB0.42884233
120RET0.42529446
121NME20.42142467
122AURKA0.41538265
123PDK10.41116875
124LMTK20.41115672
125UHMK10.40567189
126ATR0.40297116
127CDK20.39465080
128BRSK10.38859351
129MAP2K10.38513764
130MAP3K30.37456421
131CDK80.37249508
132DAPK10.37115344
133CSF1R0.37025252
134AKT20.36937980
135MELK0.33591560
136MAPK120.33421314
137MAP3K140.30317984

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052202.13305518
2Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.86402743
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84835295
4Bladder cancer_Homo sapiens_hsa052191.84450960
5DNA replication_Homo sapiens_hsa030301.77641958
6Notch signaling pathway_Homo sapiens_hsa043301.71727039
7RNA transport_Homo sapiens_hsa030131.61099884
8Other glycan degradation_Homo sapiens_hsa005111.60715351
9Mismatch repair_Homo sapiens_hsa034301.58011198
10mRNA surveillance pathway_Homo sapiens_hsa030151.57433204
11Hippo signaling pathway_Homo sapiens_hsa043901.56824763
12MicroRNAs in cancer_Homo sapiens_hsa052061.56501759
13Colorectal cancer_Homo sapiens_hsa052101.54924224
14Proteoglycans in cancer_Homo sapiens_hsa052051.54783944
15Small cell lung cancer_Homo sapiens_hsa052221.51280949
16Spliceosome_Homo sapiens_hsa030401.48645819
17Shigellosis_Homo sapiens_hsa051311.48604923
18Adherens junction_Homo sapiens_hsa045201.46669826
19Non-small cell lung cancer_Homo sapiens_hsa052231.44485866
20Biosynthesis of amino acids_Homo sapiens_hsa012301.42561528
21Base excision repair_Homo sapiens_hsa034101.42191928
22Endometrial cancer_Homo sapiens_hsa052131.40973399
23Sulfur relay system_Homo sapiens_hsa041221.40443400
24Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38716184
25Pentose phosphate pathway_Homo sapiens_hsa000301.38410740
26Cell cycle_Homo sapiens_hsa041101.37771566
27AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.37247543
28Pancreatic cancer_Homo sapiens_hsa052121.36513872
29Cyanoamino acid metabolism_Homo sapiens_hsa004601.35691531
30mTOR signaling pathway_Homo sapiens_hsa041501.33555540
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.31988659
32Acute myeloid leukemia_Homo sapiens_hsa052211.31454681
33HTLV-I infection_Homo sapiens_hsa051661.29998698
34VEGF signaling pathway_Homo sapiens_hsa043701.29061811
35Antigen processing and presentation_Homo sapiens_hsa046121.28155949
36Focal adhesion_Homo sapiens_hsa045101.26660781
37Basal cell carcinoma_Homo sapiens_hsa052171.24975802
38p53 signaling pathway_Homo sapiens_hsa041151.24663212
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.24567570
40Fructose and mannose metabolism_Homo sapiens_hsa000511.24482201
41Hepatitis B_Homo sapiens_hsa051611.23619004
42Viral myocarditis_Homo sapiens_hsa054161.23313458
43Viral carcinogenesis_Homo sapiens_hsa052031.22645495
44Leukocyte transendothelial migration_Homo sapiens_hsa046701.22523918
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.21790270
46Insulin signaling pathway_Homo sapiens_hsa049101.21594079
47Thyroid cancer_Homo sapiens_hsa052161.20627774
48Apoptosis_Homo sapiens_hsa042101.19912737
49Glioma_Homo sapiens_hsa052141.19891707
50B cell receptor signaling pathway_Homo sapiens_hsa046621.19393548
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.18821733
52Leishmaniasis_Homo sapiens_hsa051401.17812561
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.15730351
54Toxoplasmosis_Homo sapiens_hsa051451.14793711
55Renal cell carcinoma_Homo sapiens_hsa052111.09937113
56Legionellosis_Homo sapiens_hsa051341.09779594
57Inositol phosphate metabolism_Homo sapiens_hsa005621.08400433
58Prion diseases_Homo sapiens_hsa050201.06241520
59Hepatitis C_Homo sapiens_hsa051601.05651488
60Ribosome_Homo sapiens_hsa030101.04630624
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.03541248
62Amoebiasis_Homo sapiens_hsa051461.02697515
63Osteoclast differentiation_Homo sapiens_hsa043801.01318072
64Transcriptional misregulation in cancer_Homo sapiens_hsa052021.01003182
65Central carbon metabolism in cancer_Homo sapiens_hsa052301.00997615
66TGF-beta signaling pathway_Homo sapiens_hsa043500.99991518
67Choline metabolism in cancer_Homo sapiens_hsa052310.98692014
68Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97070375
69Pathways in cancer_Homo sapiens_hsa052000.96942701
702-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96852436
71Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.96580895
72AMPK signaling pathway_Homo sapiens_hsa041520.96032172
73TNF signaling pathway_Homo sapiens_hsa046680.93536729
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.93479927
75Prostate cancer_Homo sapiens_hsa052150.93035704
76Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92625853
77ECM-receptor interaction_Homo sapiens_hsa045120.92328578
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.92175830
79Hedgehog signaling pathway_Homo sapiens_hsa043400.91270677
80Prolactin signaling pathway_Homo sapiens_hsa049170.91062978
81Herpes simplex infection_Homo sapiens_hsa051680.91029796
82N-Glycan biosynthesis_Homo sapiens_hsa005100.87699618
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86672472
84Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.85701851
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85623539
86Nucleotide excision repair_Homo sapiens_hsa034200.84823240
87Estrogen signaling pathway_Homo sapiens_hsa049150.84387486
88Salmonella infection_Homo sapiens_hsa051320.84026818
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82978134
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.82959001
91Galactose metabolism_Homo sapiens_hsa000520.82670292
92Tight junction_Homo sapiens_hsa045300.81411217
93Epstein-Barr virus infection_Homo sapiens_hsa051690.81349595
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81308931
95Pertussis_Homo sapiens_hsa051330.80791364
96Measles_Homo sapiens_hsa051620.80495922
97Platelet activation_Homo sapiens_hsa046110.79555853
98Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78250645
99Endocytosis_Homo sapiens_hsa041440.78186318
100Tuberculosis_Homo sapiens_hsa051520.76546829
101Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76127612
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.74573001
103Lysine degradation_Homo sapiens_hsa003100.74011844
104Rap1 signaling pathway_Homo sapiens_hsa040150.73085218
105GnRH signaling pathway_Homo sapiens_hsa049120.72280757
106Influenza A_Homo sapiens_hsa051640.71902371
107T cell receptor signaling pathway_Homo sapiens_hsa046600.71805436
108NF-kappa B signaling pathway_Homo sapiens_hsa040640.71522629
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69731183
110Long-term potentiation_Homo sapiens_hsa047200.69365639
111Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.67332971
112Toll-like receptor signaling pathway_Homo sapiens_hsa046200.66878364
113Glycosaminoglycan degradation_Homo sapiens_hsa005310.66770308
114HIF-1 signaling pathway_Homo sapiens_hsa040660.66109468
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64879679
116Carbon metabolism_Homo sapiens_hsa012000.64848611
117Insulin resistance_Homo sapiens_hsa049310.64826026
118FoxO signaling pathway_Homo sapiens_hsa040680.64051359
119One carbon pool by folate_Homo sapiens_hsa006700.63857140
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.63413144
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63296125
122Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63130859
123Wnt signaling pathway_Homo sapiens_hsa043100.61587083
124ErbB signaling pathway_Homo sapiens_hsa040120.61486085
125Oocyte meiosis_Homo sapiens_hsa041140.61381657
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.61330794
127Chemokine signaling pathway_Homo sapiens_hsa040620.60981198
128Malaria_Homo sapiens_hsa051440.60252605
129Vibrio cholerae infection_Homo sapiens_hsa051100.59961133
130NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59587817
131Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56243362
132Primary immunodeficiency_Homo sapiens_hsa053400.53017532
133Melanogenesis_Homo sapiens_hsa049160.52062232

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