QRICH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.68284766
2nuclear pore organization (GO:0006999)5.38100221
3histone H3-K36 demethylation (GO:0070544)4.63689232
4pre-miRNA processing (GO:0031054)4.44734419
5mitotic sister chromatid cohesion (GO:0007064)4.41221586
6pore complex assembly (GO:0046931)4.35180068
7DNA unwinding involved in DNA replication (GO:0006268)3.96266346
8regulation of histone H3-K9 methylation (GO:0051570)3.93532398
9DNA replication-dependent nucleosome assembly (GO:0006335)3.93493609
10DNA replication-dependent nucleosome organization (GO:0034723)3.93493609
11dosage compensation (GO:0007549)3.89730149
12mitotic nuclear envelope disassembly (GO:0007077)3.68825243
13V(D)J recombination (GO:0033151)3.67265429
14monoubiquitinated protein deubiquitination (GO:0035520)3.61045338
15gene silencing by RNA (GO:0031047)3.54498120
16regulation of RNA export from nucleus (GO:0046831)3.53098482
17translesion synthesis (GO:0019985)3.53023170
18nuclear envelope disassembly (GO:0051081)3.51384249
19membrane disassembly (GO:0030397)3.51384249
20regulation of chromatin silencing (GO:0031935)3.50685225
21piRNA metabolic process (GO:0034587)3.42972257
22histone mRNA catabolic process (GO:0071044)3.39464700
23binding of sperm to zona pellucida (GO:0007339)3.36248554
24positive regulation of granulocyte differentiation (GO:0030854)3.33504092
25synaptonemal complex assembly (GO:0007130)3.31998368
26rRNA methylation (GO:0031167)3.31203173
27chromatin assembly (GO:0031497)3.30826023
28chromatin silencing (GO:0006342)3.30382072
29acrosome assembly (GO:0001675)3.30014292
30negative regulation of histone methylation (GO:0031061)3.26813736
31peptidyl-lysine dimethylation (GO:0018027)3.26335701
32regulation of histone H3-K27 methylation (GO:0061085)3.25233350
33cilium or flagellum-dependent cell motility (GO:0001539)3.23969731
34heterochromatin organization (GO:0070828)3.23213799
35sperm-egg recognition (GO:0035036)3.23166355
36single strand break repair (GO:0000012)3.22779756
37negative thymic T cell selection (GO:0045060)3.21822968
38regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.19156124
39histone H4-K5 acetylation (GO:0043981)3.17174307
40histone H4-K8 acetylation (GO:0043982)3.17174307
41DNA duplex unwinding (GO:0032508)3.17173189
42DNA geometric change (GO:0032392)3.15876684
43male meiosis (GO:0007140)3.13715690
44synaptonemal complex organization (GO:0070193)3.13078940
45mitotic chromosome condensation (GO:0007076)3.09061302
46ribosome assembly (GO:0042255)3.07743863
47spliceosomal tri-snRNP complex assembly (GO:0000244)3.07559414
48regulation of translational fidelity (GO:0006450)3.07076735
49DNA replication initiation (GO:0006270)3.06637320
50positive regulation of histone methylation (GO:0031062)3.04640635
51fusion of sperm to egg plasma membrane (GO:0007342)3.04304507
52regulation of histone methylation (GO:0031060)3.04203418
53negative regulation of DNA repair (GO:0045738)3.01621931
54sister chromatid cohesion (GO:0007062)3.01241791
55negative T cell selection (GO:0043383)3.01104824
56histone H4-K16 acetylation (GO:0043984)3.00686503
57regulation of chromatin binding (GO:0035561)3.00633029
58histone H3-K4 methylation (GO:0051568)3.00377090
59regulation of centriole replication (GO:0046599)3.00316811
60histone lysine demethylation (GO:0070076)2.99944729
61protein-DNA complex disassembly (GO:0032986)2.99543500
62nucleosome disassembly (GO:0006337)2.99543500
63protein localization to chromosome, centromeric region (GO:0071459)2.98246948
64DNA double-strand break processing (GO:0000729)2.97118524
65gene silencing (GO:0016458)2.97009203
66cell-cell recognition (GO:0009988)2.95522881
67regulation of translational termination (GO:0006449)2.93789318
68histone H2A acetylation (GO:0043968)2.93419123
69histone deubiquitination (GO:0016578)2.90009636
70regulation of histone H3-K4 methylation (GO:0051569)2.89395620
71negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.88718176
72histone H4 acetylation (GO:0043967)2.88299814
73protein localization to kinetochore (GO:0034501)2.87630308
74IMP biosynthetic process (GO:0006188)2.87514652
75positive regulation of histone H3-K4 methylation (GO:0051571)2.86701809
76postreplication repair (GO:0006301)2.86448797
77histone demethylation (GO:0016577)2.85809719
78nucleus organization (GO:0006997)2.84102504
79chromosome condensation (GO:0030261)2.84001322
80double-strand break repair via nonhomologous end joining (GO:0006303)2.83985853
81non-recombinational repair (GO:0000726)2.83985853
82RNA stabilization (GO:0043489)2.82998400
83mRNA stabilization (GO:0048255)2.82998400
84DNA conformation change (GO:0071103)2.82167460
85acrosome reaction (GO:0007340)2.80614731
86DNA packaging (GO:0006323)2.80599871
87histone H3-K9 methylation (GO:0051567)2.80174318
88positive regulation by host of viral transcription (GO:0043923)2.79587096
89regulation of DNA damage checkpoint (GO:2000001)2.78907745
90positive regulation of mitotic sister chromatid separation (GO:1901970)2.78748961
91positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.78748961
92positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.78748961
93mRNA transport (GO:0051028)2.77506195
94mRNA splice site selection (GO:0006376)2.75989775
95ATP-dependent chromatin remodeling (GO:0043044)2.73307608
96negative regulation of mRNA metabolic process (GO:1903312)2.73174941
97DNA ligation (GO:0006266)2.71824036
98chromosome organization involved in meiosis (GO:0070192)2.71724224
99sister chromatid segregation (GO:0000819)2.71634407
100DNA strand elongation involved in DNA replication (GO:0006271)2.71475509
101nuclear envelope organization (GO:0006998)2.70218295
102multicellular organism reproduction (GO:0032504)2.68208086
103regulation of centrosome cycle (GO:0046605)2.68178924
104folic acid-containing compound biosynthetic process (GO:0009396)2.68116447
105nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.67704931
106regulation of gene silencing (GO:0060968)2.67234067
107chromatin assembly or disassembly (GO:0006333)2.66965841
108rRNA modification (GO:0000154)2.66960184
109mRNA cleavage (GO:0006379)2.66914192
110protein dealkylation (GO:0008214)2.66424815
111protein demethylation (GO:0006482)2.66424815
112poly(A)+ mRNA export from nucleus (GO:0016973)2.66038628
113negative regulation of RNA splicing (GO:0033119)2.63807833
114genitalia morphogenesis (GO:0035112)2.62397861
115regulation of chromosome segregation (GO:0051983)2.61050061
116histone H3-K4 trimethylation (GO:0080182)2.60401272
117NLS-bearing protein import into nucleus (GO:0006607)2.59581716
118regulation of nucleobase-containing compound transport (GO:0032239)2.58371999
119histone H3 acetylation (GO:0043966)2.57953809
120negative regulation of histone modification (GO:0031057)2.57593422
121negative regulation of chromosome segregation (GO:0051985)2.57435610
122DNA strand elongation (GO:0022616)2.57431405
123ncRNA catabolic process (GO:0034661)2.56858398
124alternative mRNA splicing, via spliceosome (GO:0000380)2.56814225
125regulation of DNA endoreduplication (GO:0032875)2.56743242
126regulation of gene silencing by miRNA (GO:0060964)2.56558062
127regulation of gene silencing by RNA (GO:0060966)2.56558062
128regulation of posttranscriptional gene silencing (GO:0060147)2.56558062
129negative regulation of gene silencing (GO:0060969)2.55733840
130regulation of mitotic metaphase/anaphase transition (GO:0030071)2.55028170
131sperm motility (GO:0030317)2.54690241
132negative regulation of mRNA processing (GO:0050686)2.54033562
133negative regulation of mitotic sister chromatid separation (GO:2000816)2.53853888
134negative regulation of mitotic sister chromatid segregation (GO:0033048)2.53853888
135negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.53853888
136negative regulation of sister chromatid segregation (GO:0033046)2.53853888
137mRNA export from nucleus (GO:0006406)2.52134278
138histone lysine methylation (GO:0034968)2.51429376
139somatic cell DNA recombination (GO:0016444)2.51230200
140somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.51230200
141negative regulation of gene expression, epigenetic (GO:0045814)2.51060730
142RNA export from nucleus (GO:0006405)2.50980387
143intra-S DNA damage checkpoint (GO:0031573)2.50930757
144COPII vesicle coating (GO:0048208)2.50716737
145protein K11-linked deubiquitination (GO:0035871)2.49721557
146DNA methylation (GO:0006306)2.49629163
147DNA alkylation (GO:0006305)2.49629163
148regulation of telomere maintenance via telomerase (GO:0032210)2.49245727
149somatic hypermutation of immunoglobulin genes (GO:0016446)2.49094077
150somatic diversification of immune receptors via somatic mutation (GO:0002566)2.49094077
151peptidyl-lysine trimethylation (GO:0018023)2.48773874
152histone exchange (GO:0043486)2.48759715
153positive regulation of gene expression, epigenetic (GO:0045815)2.48714369
154spindle assembly checkpoint (GO:0071173)2.48237839
155positive regulation of chromosome segregation (GO:0051984)2.47760305
156establishment of RNA localization (GO:0051236)2.47697841
157microtubule nucleation (GO:0007020)2.46475859
158positive T cell selection (GO:0043368)2.44723465

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.33892194
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.64803118
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.46323785
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.86027596
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.76814980
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.34514027
7MYC_22102868_ChIP-Seq_BL_Human2.90290972
8* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88775051
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.77484397
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.57728397
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.47085781
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.31594717
13E2F1_21310950_ChIP-Seq_MCF-7_Human2.24248163
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.13786848
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.11658375
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06488676
17ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.06037150
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.02142800
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.01713346
20TP63_19390658_ChIP-ChIP_HaCaT_Human1.97344614
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.95259434
22* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.83215744
23* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.81188407
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.80858550
25MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80258781
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77326186
27KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.75248937
28CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.73466869
29* CIITA_25753668_ChIP-Seq_RAJI_Human1.69506454
30SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.64006484
31AR_21909140_ChIP-Seq_LNCAP_Human1.60225098
32TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.54591392
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.53040725
34IRF8_22096565_ChIP-ChIP_GC-B_Human1.52925921
35* XRN2_22483619_ChIP-Seq_HELA_Human1.51116654
36MYC_18358816_ChIP-ChIP_MESCs_Mouse1.49770597
37DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.49765411
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48633299
39* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48492589
40TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47440701
41ETS1_20019798_ChIP-Seq_JURKAT_Human1.46541113
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46468362
43VDR_23849224_ChIP-Seq_CD4+_Human1.46113577
44BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.45515283
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42667812
46FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.42348719
47MAF_26560356_Chip-Seq_TH2_Human1.40292618
48CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38644924
49* TCF7_22412390_ChIP-Seq_EML_Mouse1.37026254
50BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.33910028
51KDM5A_27292631_Chip-Seq_BREAST_Human1.33561408
52SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.31599612
53* FOXP3_21729870_ChIP-Seq_TREG_Human1.30647737
54TFEB_21752829_ChIP-Seq_HELA_Human1.30021800
55VDR_21846776_ChIP-Seq_THP-1_Human1.29999241
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.29942674
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.23490598
58MYB_26560356_Chip-Seq_TH2_Human1.23330769
59ELK1_19687146_ChIP-ChIP_HELA_Human1.22271440
60UTX_26944678_Chip-Seq_JUKART_Human1.22121975
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.20302920
62YY1_21170310_ChIP-Seq_MESCs_Mouse1.19840542
63KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.19608517
64MYB_26560356_Chip-Seq_TH1_Human1.18741309
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.18051057
66GABP_19822575_ChIP-Seq_HepG2_Human1.17574717
67* TTF2_22483619_ChIP-Seq_HELA_Human1.16979683
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.15996116
69* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14437700
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13668595
71E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.13652610
72MAF_26560356_Chip-Seq_TH1_Human1.13567344
73ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13254179
74CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12813788
75RUNX_20019798_ChIP-Seq_JUKART_Human1.12362217
76ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12288130
77MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.12279009
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11948050
79KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09628001
80KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09628001
81KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09628001
82PKCTHETA_26484144_Chip-Seq_BREAST_Human1.09435237
83STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09219306
84NANOG_21062744_ChIP-ChIP_HESCs_Human1.06042919
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.05142666
86HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05063233
87CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.02462609
88E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02231734
89PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02092548
90HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01913165
91GATA3_27048872_Chip-Seq_THYMUS_Human1.01818602
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00832544
93STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.00723292
94IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.00640396
95FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00354404
96ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99780549
97STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.99333356
98STAT4_19710469_ChIP-ChIP_TH1__Mouse0.99288187
99EST1_17652178_ChIP-ChIP_JURKAT_Human0.98310017
100KDM2B_26808549_Chip-Seq_DND41_Human0.97643870
101BRD4_27068464_Chip-Seq_AML-cells_Mouse0.95610438
102ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95291726
103KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94411455
104SCL_19346495_ChIP-Seq_HPC-7_Human0.94158829
105PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94074240
106MYB_21317192_ChIP-Seq_ERMYB_Mouse0.93747844
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.93329808
108* RUNX1_22412390_ChIP-Seq_EML_Mouse0.92844021
109E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.91965753
110FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.91774789
111SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.91496807
112* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.91412030
113POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.90142743
114CREB1_15753290_ChIP-ChIP_HEK293T_Human0.89286239
115* SPI1_23547873_ChIP-Seq_NB4_Human0.88759665
116CHD1_26751641_Chip-Seq_LNCaP_Human0.87842376
117* HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.87809122
118GABP_17652178_ChIP-ChIP_JURKAT_Human0.85902822
119DCP1A_22483619_ChIP-Seq_HELA_Human0.85505263

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.19275409
2MP0010094_abnormal_chromosome_stability3.14928143
3MP0008007_abnormal_cellular_replicative3.03629168
4MP0008877_abnormal_DNA_methylation2.94424001
5MP0005410_abnormal_fertilization2.81859977
6MP0003111_abnormal_nucleus_morphology2.80257350
7MP0010352_gastrointestinal_tract_polyps2.76113980
8MP0003077_abnormal_cell_cycle2.71546103
9MP0004957_abnormal_blastocyst_morpholog2.52902229
10MP0003693_abnormal_embryo_hatching2.46362213
11MP0008058_abnormal_DNA_repair2.40478574
12MP0005076_abnormal_cell_differentiation2.31621894
13MP0010307_abnormal_tumor_latency2.28935707
14MP0001730_embryonic_growth_arrest2.01337620
15MP0004808_abnormal_hematopoietic_stem1.92907933
16MP0000350_abnormal_cell_proliferation1.92069709
17MP0008995_early_reproductive_senescence1.85507611
18MP0002254_reproductive_system_inflammat1.84979081
19MP0001929_abnormal_gametogenesis1.76369744
20MP0001672_abnormal_embryogenesis/_devel1.75942527
21MP0005380_embryogenesis_phenotype1.75942527
22MP0000569_abnormal_digit_pigmentation1.75758679
23MP0004197_abnormal_fetal_growth/weight/1.73674623
24MP0002084_abnormal_developmental_patter1.71410980
25MP0003763_abnormal_thymus_physiology1.71064777
26MP0003984_embryonic_growth_retardation1.69896353
27MP0002396_abnormal_hematopoietic_system1.68735029
28MP0002088_abnormal_embryonic_growth/wei1.68286848
29MP0003172_abnormal_lysosome_physiology1.67811953
30MP0006054_spinal_hemorrhage1.67757773
31MP0000537_abnormal_urethra_morphology1.67600923
32MP0003123_paternal_imprinting1.67407745
33MP0001697_abnormal_embryo_size1.61608623
34MP0002210_abnormal_sex_determination1.60330552
35MP0002085_abnormal_embryonic_tissue1.53962600
36MP0003890_abnormal_embryonic-extraembry1.51299416
37MP0002086_abnormal_extraembryonic_tissu1.51190183
38MP0002653_abnormal_ependyma_morphology1.50886947
39MP0003698_abnormal_male_reproductive1.48756374
40MP0008932_abnormal_embryonic_tissue1.48214974
41MP0001293_anophthalmia1.46319504
42MP0010234_abnormal_vibrissa_follicle1.45531958
43MP0005075_abnormal_melanosome_morpholog1.44005847
44MP0004185_abnormal_adipocyte_glucose1.43204554
45MP0003718_maternal_effect1.41000485
46MP0001873_stomach_inflammation1.40832462
47MP0003121_genomic_imprinting1.39437928
48MP0002877_abnormal_melanocyte_morpholog1.39416823
49MP0000703_abnormal_thymus_morphology1.38382581
50MP0001145_abnormal_male_reproductive1.36503007
51MP0002166_altered_tumor_susceptibility1.36066259
52MP0002080_prenatal_lethality1.35710843
53MP0001661_extended_life_span1.35200554
54MP0005220_abnormal_exocrine_pancreas1.34205832
55MP0009333_abnormal_splenocyte_physiolog1.33577321
56MP0009278_abnormal_bone_marrow1.32011592
57MP0003705_abnormal_hypodermis_morpholog1.31450252
58MP0001915_intracranial_hemorrhage1.30650886
59MP0010030_abnormal_orbit_morphology1.28208612
60MP0000015_abnormal_ear_pigmentation1.25628587
61MP0003787_abnormal_imprinting1.21959174
62MP0000733_abnormal_muscle_development1.21664493
63MP0003567_abnormal_fetal_cardiomyocyte1.18874739
64MP0009053_abnormal_anal_canal1.16386901
65MP0000465_gastrointestinal_hemorrhage1.16374105
66MP0000313_abnormal_cell_death1.14751525
67MP0002398_abnormal_bone_marrow1.14233819
68MP0002019_abnormal_tumor_incidence1.13523659
69MP0002006_tumorigenesis1.11854017
70MP0003436_decreased_susceptibility_to1.11090876
71MP0000428_abnormal_craniofacial_morphol1.10936671
72MP0004381_abnormal_hair_follicle1.09839849
73MP0003786_premature_aging1.09565735
74MP0000653_abnormal_sex_gland1.09250587
75MP0002282_abnormal_trachea_morphology1.07992403
76MP0000490_abnormal_crypts_of1.07856266
77MP0000678_abnormal_parathyroid_gland1.05088288
78MP0001800_abnormal_humoral_immune1.04513018
79MP0001348_abnormal_lacrimal_gland1.03982243
80MP0002697_abnormal_eye_size1.03565172
81MP0009703_decreased_birth_body1.02655771
82MP0003119_abnormal_digestive_system1.02024099
83MP0001545_abnormal_hematopoietic_system1.00926349
84MP0005397_hematopoietic_system_phenotyp1.00926349
85MP0003300_gastrointestinal_ulcer1.00507975
86MP0000685_abnormal_immune_system0.99992461
87MP0003115_abnormal_respiratory_system0.98712930
88MP0000003_abnormal_adipose_tissue0.98492222
89MP0005310_abnormal_salivary_gland0.98323905
90MP0003943_abnormal_hepatobiliary_system0.97119849
91MP0003566_abnormal_cell_adhesion0.96633140
92MP0002925_abnormal_cardiovascular_devel0.95887568
93MP0003283_abnormal_digestive_organ0.93640898
94MP0009672_abnormal_birth_weight0.93532841
95MP0003935_abnormal_craniofacial_develop0.92917301
96MP0005623_abnormal_meninges_morphology0.92308313
97MP0001243_abnormal_dermal_layer0.92225808
98MP0002722_abnormal_immune_system0.92214476
99MP0000432_abnormal_head_morphology0.90519091
100MP0002420_abnormal_adaptive_immunity0.89793544
101MP0000858_altered_metastatic_potential0.89254459
102MP0001119_abnormal_female_reproductive0.89195295
103MP0005647_abnormal_sex_gland0.89062978
104MP0003699_abnormal_female_reproductive0.88986720
105MP0001853_heart_inflammation0.88853854
106MP0002092_abnormal_eye_morphology0.87679002
107MP0002161_abnormal_fertility/fecundity0.87382207
108MP0001819_abnormal_immune_cell0.86439602
109MP0000371_diluted_coat_color0.84817087
110MP0001944_abnormal_pancreas_morphology0.84683932
111MP0005451_abnormal_body_composition0.84317886
112MP0008961_abnormal_basal_metabolism0.84135850
113MP0000689_abnormal_spleen_morphology0.83303896
114MP0002405_respiratory_system_inflammati0.81306603
115MP0005000_abnormal_immune_tolerance0.81302634
116MP0005023_abnormal_wound_healing0.81291745
117MP0000372_irregular_coat_pigmentation0.80905493
118MP0002009_preneoplasia0.80711845
119MP0003091_abnormal_cell_migration0.79633629
120MP0001849_ear_inflammation0.79152927
121MP0005671_abnormal_response_to0.78753150
122MP0005248_abnormal_Harderian_gland0.78522937
123MP0004264_abnormal_extraembryonic_tissu0.78413012
124MP0002970_abnormal_white_adipose0.78260477
125MP0003448_altered_tumor_morphology0.78245241
126MP0000613_abnormal_salivary_gland0.78021780
127MP0000516_abnormal_urinary_system0.77613733
128MP0005367_renal/urinary_system_phenotyp0.77613733
129MP0002160_abnormal_reproductive_system0.77460076
130MP0002138_abnormal_hepatobiliary_system0.74554578
131MP0002111_abnormal_tail_morphology0.73912271
132MP0002429_abnormal_blood_cell0.73765549
133MP0003861_abnormal_nervous_system0.73511866
134MP0003937_abnormal_limbs/digits/tail_de0.73401639
135MP0005670_abnormal_white_adipose0.72780468
136MP0005379_endocrine/exocrine_gland_phen0.72648743
137MP0003183_abnormal_peptide_metabolism0.72525306
138MP0005384_cellular_phenotype0.72476289
139MP0000716_abnormal_immune_system0.71949426
140MP0005621_abnormal_cell_physiology0.71654921

Predicted human phenotypes

RankGene SetZ-score
1Neoplasm of the adrenal cortex (HP:0100641)4.20490528
2Abnormality of endocrine pancreas physiology (HP:0012093)3.61576591
3Abnormality of the pancreatic islet cells (HP:0006476)3.61576591
4Nephroblastoma (Wilms tumor) (HP:0002667)3.41787222
5Pancreatic islet-cell hyperplasia (HP:0004510)3.30296155
6Short 4th metacarpal (HP:0010044)3.30046321
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.30046321
8Embryonal renal neoplasm (HP:0011794)3.24753758
9Degeneration of anterior horn cells (HP:0002398)2.90823958
10Abnormality of the anterior horn cell (HP:0006802)2.90823958
11Facial hemangioma (HP:0000329)2.88903172
12Panhypogammaglobulinemia (HP:0003139)2.87733782
13Hypoglycemic seizures (HP:0002173)2.85485059
14Basal cell carcinoma (HP:0002671)2.83755046
15Selective tooth agenesis (HP:0001592)2.82302985
16Hypoplastic labia majora (HP:0000059)2.80838270
17Severe combined immunodeficiency (HP:0004430)2.75593780
18Increased density of long bones (HP:0006392)2.65244717
19Abnormality of the lower motor neuron (HP:0002366)2.61861872
20Ependymoma (HP:0002888)2.60165789
21Volvulus (HP:0002580)2.58731922
22Abnormal hair whorl (HP:0010721)2.54764596
23High pitched voice (HP:0001620)2.49024653
24Abnormality of the labia majora (HP:0012881)2.48108093
25Abnormality of the preputium (HP:0100587)2.47309810
26Combined immunodeficiency (HP:0005387)2.45924607
27Abnormality of the fingertips (HP:0001211)2.45664534
28Deep palmar crease (HP:0006191)2.44662131
2911 pairs of ribs (HP:0000878)2.44215786
30B lymphocytopenia (HP:0010976)2.43928426
31Microvesicular hepatic steatosis (HP:0001414)2.42798302
32Insulin-resistant diabetes mellitus (HP:0000831)2.42782130
33Hypergonadotropic hypogonadism (HP:0000815)2.41548650
34Absent frontal sinuses (HP:0002688)2.40998572
35Ectopic kidney (HP:0000086)2.38305425
36T lymphocytopenia (HP:0005403)2.33816562
37Embryonal neoplasm (HP:0002898)2.33356652
38Severe visual impairment (HP:0001141)2.32916151
39Increased nuchal translucency (HP:0010880)2.30630767
40Abnormality of the metopic suture (HP:0005556)2.29895385
41Abnormality of DNA repair (HP:0003254)2.29193709
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.29106327
43Cutaneous melanoma (HP:0012056)2.29098539
44Symptomatic seizures (HP:0011145)2.27790081
45Medulloblastoma (HP:0002885)2.26810223
46Deviation of the thumb (HP:0009603)2.26396115
47Heterotopia (HP:0002282)2.25594568
48Urethral obstruction (HP:0000796)2.25189894
49Abnormality of the astrocytes (HP:0100707)2.23243838
50Astrocytoma (HP:0009592)2.23243838
51Long eyelashes (HP:0000527)2.22952696
52Chronic hepatic failure (HP:0100626)2.22750760
53Aqueductal stenosis (HP:0002410)2.22444121
54Amyotrophic lateral sclerosis (HP:0007354)2.22154934
55Proximal placement of thumb (HP:0009623)2.22140935
56Missing ribs (HP:0000921)2.22042959
57Abnormality of the 4th metacarpal (HP:0010012)2.20718001
58Chronic diarrhea (HP:0002028)2.20674402
59Abnormality of B cell number (HP:0010975)2.19566931
60Abnormality of the aortic arch (HP:0012303)2.14897470
61Nasal polyposis (HP:0100582)2.11804561
62Cafe-au-lait spot (HP:0000957)2.10227369
63Abnormality of the parathyroid morphology (HP:0011766)2.09833237
64Prominent nose (HP:0000448)2.09569762
65Broad face (HP:0000283)2.08468485
66Squamous cell carcinoma (HP:0002860)2.06641665
67Broad alveolar ridges (HP:0000187)2.06523869
68IgG deficiency (HP:0004315)2.06169795
69Tented upper lip vermilion (HP:0010804)2.05162231
70Unilateral renal agenesis (HP:0000122)2.05056245
71Aplasia/Hypoplasia of the sternum (HP:0006714)2.04511971
72Trigonocephaly (HP:0000243)2.04485020
73Insulin resistance (HP:0000855)2.03450542
74Hepatoblastoma (HP:0002884)2.03345235
75Birth length less than 3rd percentile (HP:0003561)2.01893280
76Chromsome breakage (HP:0040012)2.01319440
77Intestinal atresia (HP:0011100)2.00011113
78Hyperinsulinemic hypoglycemia (HP:0000825)1.99444923
79Shallow orbits (HP:0000586)1.98761261
80Entropion (HP:0000621)1.97398788
81Hypoplasia of the thymus (HP:0000778)1.95778696
82Recurrent viral infections (HP:0004429)1.95666619
83Neoplasm of the adrenal gland (HP:0100631)1.95192520
84Atrophy/Degeneration involving motor neurons (HP:0007373)1.95021431
85Abnormality of chromosome segregation (HP:0002916)1.94195313
86Hyperacusis (HP:0010780)1.93943054
87Agnosia (HP:0010524)1.92149343
88Colon cancer (HP:0003003)1.91938375
89Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.91774395
90Short 1st metacarpal (HP:0010034)1.91774395
91Chromosomal breakage induced by crosslinking agents (HP:0003221)1.91559864
92Chronic bronchitis (HP:0004469)1.91527205
93Bicuspid aortic valve (HP:0001647)1.88867446
94Absent/shortened dynein arms (HP:0200106)1.88852846
95Dynein arm defect of respiratory motile cilia (HP:0012255)1.88852846
96Abnormality of T cell number (HP:0011839)1.88385596
97Abnormality of the labia minora (HP:0012880)1.88326251
98Abnormality of chromosome stability (HP:0003220)1.87874850
99Truncal obesity (HP:0001956)1.87713834
100Malignant gastrointestinal tract tumors (HP:0006749)1.86217270
101Gastrointestinal carcinoma (HP:0002672)1.86217270
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.85817970
103Lymphopenia (HP:0001888)1.85343752
104Fatigue (HP:0012378)1.84787944
105Stomatitis (HP:0010280)1.84487477
106Abdominal situs inversus (HP:0003363)1.84264276
107Abnormality of abdominal situs (HP:0011620)1.84264276
108Progressive external ophthalmoplegia (HP:0000590)1.83806599
109Broad palm (HP:0001169)1.82970410
110Thyroiditis (HP:0100646)1.82511784
111Long palpebral fissure (HP:0000637)1.82445663
112Abnormality of T cells (HP:0002843)1.81343176
113Glioma (HP:0009733)1.81243377
114Impulsivity (HP:0100710)1.81021884
115Neoplasm of the oral cavity (HP:0100649)1.80660022
116Myelodysplasia (HP:0002863)1.80580837
117Homocystinuria (HP:0002156)1.80263002
118Abnormality of homocysteine metabolism (HP:0010919)1.80263002
119Premature ovarian failure (HP:0008209)1.79832678
120Broad phalanges of the hand (HP:0009768)1.79009511
121Long clavicles (HP:0000890)1.78990245
122Dislocated radial head (HP:0003083)1.78637702
123Supernumerary spleens (HP:0009799)1.78620897
124IgA deficiency (HP:0002720)1.78479231
125Bronchitis (HP:0012387)1.78362356
126Abnormality of the radial head (HP:0003995)1.77864709
127Small intestinal stenosis (HP:0012848)1.77655728
128Duodenal stenosis (HP:0100867)1.77655728
129Broad thumb (HP:0011304)1.77283295
130Renovascular hypertension (HP:0100817)1.76926625
131Gonadotropin excess (HP:0000837)1.76592132
132Renal duplication (HP:0000075)1.76482618
133Acute myeloid leukemia (HP:0004808)1.75583479
134Cutis marmorata (HP:0000965)1.73855641
135Abnormality of cells of the lymphoid lineage (HP:0012140)1.73669229
136Abnormality of the nasal mucosa (HP:0000433)1.73640545
137Anal stenosis (HP:0002025)1.73061411
138Meckel diverticulum (HP:0002245)1.72828733
139Skull defect (HP:0001362)1.72725862
140IgM deficiency (HP:0002850)1.72455232
141Gastrointestinal inflammation (HP:0004386)1.71905106
142Rhabdomyosarcoma (HP:0002859)1.71865784
143Short humerus (HP:0005792)1.71440492
144Sensory axonal neuropathy (HP:0003390)1.71182876
145Short ribs (HP:0000773)1.70306989
146Aplasia/Hypoplasia of the earlobes (HP:0009906)1.69902532
147Recurrent bronchitis (HP:0002837)1.69585790
148Sloping forehead (HP:0000340)1.69539166
149Overlapping toe (HP:0001845)1.69507735
150Agammaglobulinemia (HP:0004432)1.69240374
151Atresia of the external auditory canal (HP:0000413)1.68883124
152Prominent metopic ridge (HP:0005487)1.68766590
153Abnormality of the carotid arteries (HP:0005344)1.68657436
154Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.67893204
155Tetany (HP:0001281)1.67537438
156Abnormality of the ileum (HP:0001549)1.67426944
157Abnormality of the duodenum (HP:0002246)1.65971352
158Upper motor neuron abnormality (HP:0002127)1.65047347
159Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.65003587
160Obsessive-compulsive behavior (HP:0000722)1.62281933
161Short phalanx of the thumb (HP:0009660)1.61585804
162Abnormal lung lobation (HP:0002101)1.61349827
163Narrow palate (HP:0000189)1.61200015
164Neoplasm of striated muscle (HP:0009728)1.60228721
165Amaurosis fugax (HP:0100576)1.58841326
166Spinal muscular atrophy (HP:0007269)1.58760480
167Cerebral aneurysm (HP:0004944)1.58583838
168Aplasia/hypoplasia of the humerus (HP:0006507)1.57849600
169Deep philtrum (HP:0002002)1.57353599

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.85691942
2CDC73.58856586
3PASK3.12143825
4TESK13.00551691
5SIK32.86127446
6EEF2K2.74154191
7SMG12.57822877
8MAP4K22.56795585
9SCYL22.49706970
10MAP3K102.44842719
11NEK22.40512549
12PDK42.28733479
13PDK32.28733479
14TAF12.16079721
15TRIM282.13931767
16FGFR22.08250810
17BRD42.02383249
18WEE11.99120938
19PRPF4B1.88763195
20PKN21.86602015
21TGFBR11.86122962
22DYRK31.75273910
23ATR1.63536397
24MST41.59916224
25SRPK11.55126331
26CDK71.54257316
27TESK21.53397232
28FLT31.52816238
29STK101.45672636
30MKNK11.42728994
31RPS6KA41.42034325
32TSSK61.37830802
33VRK21.35340587
34PDK21.31554218
35CHEK11.29213655
36PDGFRA1.26654588
37MAP4K11.19336851
38MKNK21.18509034
39RPS6KB21.17671946
40CDK41.16450585
41ICK1.15839191
42ATM1.14643810
43MTOR1.14032861
44PRKD31.13753908
45STK41.12929129
46PIM11.11985621
47BUB11.10850283
48TTK1.09531760
49PLK11.08920042
50TRIB31.08371848
51CDK91.06565281
52ACVR1B1.03570487
53CHEK21.03555341
54AURKB0.99714409
55NUAK10.99389068
56BRSK20.99014296
57CDK80.97984885
58STK30.97806886
59PLK30.97686284
60CAMK1D0.96977822
61CHUK0.96294969
62PAK40.96060745
63FRK0.94083593
64DYRK1B0.93010301
65MAP3K80.90796268
66HIPK20.88801145
67TLK10.88139260
68JAK30.87336942
69CLK10.85556538
70CDK20.85396521
71CDK60.84848430
72NEK10.84625613
73YES10.84571603
74TGFBR20.83715887
75VRK10.82421939
76MAP2K30.81004044
77FGFR30.80515180
78ZAP700.73096266
79PLK40.72614811
80LATS10.72462486
81STK380.72380412
82PLK20.71520212
83TTN0.70661430
84PRKD20.66953242
85AKT30.64907363
86EIF2AK30.64831850
87ITK0.64018375
88MAPK110.63392084
89TAOK20.63190284
90CSNK1G10.63062151
91ZAK0.62776380
92CDK10.61630621
93EIF2AK20.61183705
94PDGFRB0.59694066
95FGFR10.59018652
96STK38L0.59001715
97SIK20.58085595
98TNIK0.57435232
99MARK30.54622774
100ERBB30.54366469
101EPHA20.53857464
102CAMK1G0.53238574
103PAK20.52939834
104ERN10.52932460
105PTK60.52802673
106ALK0.52335726
107KSR10.51910336
108MELK0.51789048
109IRAK40.49227960
110CSF1R0.48689569
111BCR0.48539802
112RPS6KA50.47253135
113MAPK140.47213141
114RPS6KB10.46520415
115AKT10.46468962
116EIF2AK10.45654442
117MAP3K70.44296631
118LRRK20.43695261
119TXK0.42881603
120INSRR0.42688458
121FGFR40.42674102
122SIK10.42309420
123LCK0.42029540
124MAPK10.41880651
125CCNB10.41293436
126CSNK1D0.40749272
127AURKA0.40500380
128TYRO30.40374119
129GSK3B0.39894989
130RPS6KA10.39834824
131BMPR1B0.38274322
132PRKDC0.37867444
133NLK0.37633444
134NEK90.37615453
135MAPK80.36133750
136IKBKB0.34224404
137MAP3K30.33208084
138EPHA30.33113925
139CSNK1G30.32805061
140SGK30.32399164
141TAOK10.32119526

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.07081978
2Mismatch repair_Homo sapiens_hsa034302.53275521
3RNA transport_Homo sapiens_hsa030132.42059382
4Spliceosome_Homo sapiens_hsa030402.39971313
5Cell cycle_Homo sapiens_hsa041102.39923402
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.27275736
7Systemic lupus erythematosus_Homo sapiens_hsa053222.15775149
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.13884757
9mRNA surveillance pathway_Homo sapiens_hsa030152.04436876
10Fanconi anemia pathway_Homo sapiens_hsa034601.89575581
11Base excision repair_Homo sapiens_hsa034101.85343066
12Homologous recombination_Homo sapiens_hsa034401.78655691
13Viral carcinogenesis_Homo sapiens_hsa052031.78263166
14Non-homologous end-joining_Homo sapiens_hsa034501.67164709
15Nucleotide excision repair_Homo sapiens_hsa034201.64604581
16Antigen processing and presentation_Homo sapiens_hsa046121.64567504
17RNA degradation_Homo sapiens_hsa030181.60066782
18One carbon pool by folate_Homo sapiens_hsa006701.59801964
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.54285394
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.53995400
21Inositol phosphate metabolism_Homo sapiens_hsa005621.38524335
22HTLV-I infection_Homo sapiens_hsa051661.36357117
23Notch signaling pathway_Homo sapiens_hsa043301.35826560
24p53 signaling pathway_Homo sapiens_hsa041151.35814784
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.31502099
26Basal transcription factors_Homo sapiens_hsa030221.31007076
27Chronic myeloid leukemia_Homo sapiens_hsa052201.30813427
28Herpes simplex infection_Homo sapiens_hsa051681.30809306
29MicroRNAs in cancer_Homo sapiens_hsa052061.26208560
30Colorectal cancer_Homo sapiens_hsa052101.25874779
31Transcriptional misregulation in cancer_Homo sapiens_hsa052021.25227509
32Selenocompound metabolism_Homo sapiens_hsa004501.24463354
33Circadian rhythm_Homo sapiens_hsa047101.22975388
34Alcoholism_Homo sapiens_hsa050341.22056728
35Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.19008049
36Epstein-Barr virus infection_Homo sapiens_hsa051691.17768551
37Legionellosis_Homo sapiens_hsa051341.16609458
38T cell receptor signaling pathway_Homo sapiens_hsa046601.15471701
39Small cell lung cancer_Homo sapiens_hsa052221.14967288
40Adherens junction_Homo sapiens_hsa045201.14582876
41Measles_Homo sapiens_hsa051621.12879260
42Maturity onset diabetes of the young_Homo sapiens_hsa049501.10276366
43Primary immunodeficiency_Homo sapiens_hsa053401.09716806
44Lysine degradation_Homo sapiens_hsa003101.08637407
45Oocyte meiosis_Homo sapiens_hsa041141.08330510
46mTOR signaling pathway_Homo sapiens_hsa041501.07761969
47Vitamin B6 metabolism_Homo sapiens_hsa007501.04282069
48Hepatitis B_Homo sapiens_hsa051611.03781096
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03056241
50B cell receptor signaling pathway_Homo sapiens_hsa046621.02492505
51Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99750647
52Influenza A_Homo sapiens_hsa051640.96160612
53NF-kappa B signaling pathway_Homo sapiens_hsa040640.95853692
54Basal cell carcinoma_Homo sapiens_hsa052170.95278383
55Type I diabetes mellitus_Homo sapiens_hsa049400.94755138
56Regulation of autophagy_Homo sapiens_hsa041400.93725106
57Shigellosis_Homo sapiens_hsa051310.92241551
58Acute myeloid leukemia_Homo sapiens_hsa052210.92162881
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.91277953
60Other glycan degradation_Homo sapiens_hsa005110.90700999
61Viral myocarditis_Homo sapiens_hsa054160.90389872
62Endometrial cancer_Homo sapiens_hsa052130.89151036
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.87144070
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.86400169
65Proteasome_Homo sapiens_hsa030500.83889471
66Prostate cancer_Homo sapiens_hsa052150.83845483
67RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83543228
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81854815
69Toxoplasmosis_Homo sapiens_hsa051450.81219672
70Thyroid cancer_Homo sapiens_hsa052160.81038369
71Pyrimidine metabolism_Homo sapiens_hsa002400.80996506
72TGF-beta signaling pathway_Homo sapiens_hsa043500.79321622
73Hippo signaling pathway_Homo sapiens_hsa043900.79215383
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79037345
75Apoptosis_Homo sapiens_hsa042100.77640556
76Non-small cell lung cancer_Homo sapiens_hsa052230.77550116
77Pancreatic cancer_Homo sapiens_hsa052120.75577831
78Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.75563564
79Fatty acid biosynthesis_Homo sapiens_hsa000610.75251854
80Leishmaniasis_Homo sapiens_hsa051400.74113993
81Osteoclast differentiation_Homo sapiens_hsa043800.73626972
82RNA polymerase_Homo sapiens_hsa030200.73027884
83N-Glycan biosynthesis_Homo sapiens_hsa005100.72672137
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.69936082
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69102463
86Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68705177
87Proteoglycans in cancer_Homo sapiens_hsa052050.68018265
88Wnt signaling pathway_Homo sapiens_hsa043100.67619270
89Hedgehog signaling pathway_Homo sapiens_hsa043400.65191307
90VEGF signaling pathway_Homo sapiens_hsa043700.64168245
91Glucagon signaling pathway_Homo sapiens_hsa049220.62633907
92Pathways in cancer_Homo sapiens_hsa052000.62480786
93TNF signaling pathway_Homo sapiens_hsa046680.60904392
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.60872497
95HIF-1 signaling pathway_Homo sapiens_hsa040660.60577682
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59631874
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.58900718
98Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57221518
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.56327224
100Focal adhesion_Homo sapiens_hsa045100.54941575
101Type II diabetes mellitus_Homo sapiens_hsa049300.54271837
102AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54069434
103Salmonella infection_Homo sapiens_hsa051320.52573274
104Biosynthesis of amino acids_Homo sapiens_hsa012300.52165153
105Hematopoietic cell lineage_Homo sapiens_hsa046400.50558859
106Glioma_Homo sapiens_hsa052140.50102478
107Dorso-ventral axis formation_Homo sapiens_hsa043200.50005518
108FoxO signaling pathway_Homo sapiens_hsa040680.49804657
109Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.48855701
110Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46909620
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46813862
112Purine metabolism_Homo sapiens_hsa002300.46343258
113Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.45064572
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45049787
115Prolactin signaling pathway_Homo sapiens_hsa049170.44833713
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.44165214
117Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.43207984
118Estrogen signaling pathway_Homo sapiens_hsa049150.41511317
119Bladder cancer_Homo sapiens_hsa052190.40356989
120AMPK signaling pathway_Homo sapiens_hsa041520.40286721
121Folate biosynthesis_Homo sapiens_hsa007900.39397172
122Butanoate metabolism_Homo sapiens_hsa006500.35876525
123Protein export_Homo sapiens_hsa030600.34682047
124Endocytosis_Homo sapiens_hsa041440.34060453
125Insulin resistance_Homo sapiens_hsa049310.32633718

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