RAB11FIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.97455151
2negative regulation of cell killing (GO:0031342)4.97455151
3response to peptidoglycan (GO:0032494)4.47023824
4modulation by symbiont of host immune response (GO:0052553)4.43785733
5positive regulation by symbiont of host defense response (GO:0052509)4.43785733
6modulation by symbiont of host defense response (GO:0052031)4.43785733
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.43785733
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.43785733
9positive regulation by organism of defense response of other organism involved in symbiotic interact4.43785733
10regulation of gamma-delta T cell activation (GO:0046643)4.31723900
11regulation of B cell receptor signaling pathway (GO:0050855)4.26710061
12positive regulation of heat generation (GO:0031652)4.22665686
13regulation of gamma-delta T cell differentiation (GO:0045586)4.19203681
14regulation of fever generation (GO:0031620)4.16486880
15positive regulation of chemokine biosynthetic process (GO:0045080)4.06654777
16neutrophil activation involved in immune response (GO:0002283)4.02386699
17cellular extravasation (GO:0045123)3.99738691
18positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.92582813
19response to muramyl dipeptide (GO:0032495)3.85987165
20NIK/NF-kappaB signaling (GO:0038061)3.71292685
21negative regulation of lymphocyte mediated immunity (GO:0002707)3.66516735
22neutrophil mediated immunity (GO:0002446)3.61195087
23regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.58831511
24regulation of podosome assembly (GO:0071801)3.58261211
25leukocyte aggregation (GO:0070486)3.55873501
26tolerance induction (GO:0002507)3.53527171
27lipopolysaccharide-mediated signaling pathway (GO:0031663)3.52335067
28microglial cell activation (GO:0001774)3.47356542
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.44162893
30macrophage activation (GO:0042116)3.43658909
31granulocyte activation (GO:0036230)3.42850273
32regulation of chemokine biosynthetic process (GO:0045073)3.42312440
33regulation of vitamin D biosynthetic process (GO:0060556)3.42111706
34positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.36765059
35response to interleukin-15 (GO:0070672)3.36601242
36dendritic cell migration (GO:0036336)3.34904488
37immunoglobulin mediated immune response (GO:0016064)3.33600184
38antigen processing and presentation via MHC class Ib (GO:0002475)3.32629619
39cellular response to interleukin-15 (GO:0071350)3.31882046
40regulation of regulatory T cell differentiation (GO:0045589)3.31143639
41positive regulation of interferon-alpha production (GO:0032727)3.28977422
42positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.28002418
43interferon-gamma secretion (GO:0072643)3.27514450
44neutrophil activation (GO:0042119)3.26569129
45detection of other organism (GO:0098543)3.25914603
46regulation of vitamin metabolic process (GO:0030656)3.25478520
47regulation of interleukin-12 biosynthetic process (GO:0045075)3.23697559
48positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.23101764
49positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.21619929
50regulation of heat generation (GO:0031650)3.21458877
51detection of biotic stimulus (GO:0009595)3.21400840
52regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.18935501
53regulation of dendritic cell antigen processing and presentation (GO:0002604)3.18526583
54dendritic cell chemotaxis (GO:0002407)3.18189885
55cytokine secretion (GO:0050663)3.18066904
56regulation of interferon-alpha production (GO:0032647)3.18024787
57positive regulation of NF-kappaB import into nucleus (GO:0042346)3.17725843
58response to host immune response (GO:0052572)3.17681394
59response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.17681394
60T-helper 1 type immune response (GO:0042088)3.15894199
61B cell receptor signaling pathway (GO:0050853)3.10801130
62regulation of RIG-I signaling pathway (GO:0039535)3.10736409
63superoxide anion generation (GO:0042554)3.08208891
64detection of bacterium (GO:0016045)3.06812210
65positive regulation of interleukin-12 production (GO:0032735)3.06255184
66hydrogen peroxide biosynthetic process (GO:0050665)3.04186375
67myeloid cell activation involved in immune response (GO:0002275)3.03858139
68negative regulation of leukocyte mediated immunity (GO:0002704)3.03756624
69regulation of activation of Janus kinase activity (GO:0010533)3.03695260
70positive regulation of T cell mediated cytotoxicity (GO:0001916)3.03286533
71positive regulation of interleukin-17 production (GO:0032740)3.02393584
72negative regulation of T cell mediated immunity (GO:0002710)3.01185843
73regulation of tolerance induction (GO:0002643)3.00962376
74macrophage activation involved in immune response (GO:0002281)3.00854778
75natural killer cell mediated immunity (GO:0002228)2.99841592
76natural killer cell mediated cytotoxicity (GO:0042267)2.99841592
77positive regulation of antigen processing and presentation (GO:0002579)2.99301196
78negative regulation of interleukin-12 production (GO:0032695)2.97375207
79antigen processing and presentation of endogenous antigen (GO:0019883)2.93793393
80response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.92995233
81response to host (GO:0075136)2.92995233
82response to host defenses (GO:0052200)2.92995233
83regulation of T cell mediated cytotoxicity (GO:0001914)2.90940859
84regulation of mast cell degranulation (GO:0043304)2.88753035
85positive regulation of interferon-beta production (GO:0032728)2.88165805
86negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.87732797
87positive regulation of gamma-delta T cell activation (GO:0046645)2.87598472
88germinal center formation (GO:0002467)2.84417311
89myeloid leukocyte mediated immunity (GO:0002444)2.81929873
90T-helper cell differentiation (GO:0042093)2.81563818
91CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.81563818
92positive regulation of tolerance induction (GO:0002645)2.81365432
93negative regulation of erythrocyte differentiation (GO:0045647)2.81166385
94positive regulation of cellular amide metabolic process (GO:0034250)2.80989784
95regulation of interleukin-6 biosynthetic process (GO:0045408)2.78913551
96negative regulation of immunoglobulin mediated immune response (GO:0002890)2.78233997
97negative regulation of B cell mediated immunity (GO:0002713)2.78233997
98positive regulation of mast cell activation (GO:0033005)2.77418544
99negative regulation of humoral immune response (GO:0002921)2.77048380
100negative regulation of interleukin-6 production (GO:0032715)2.76838031
101antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.76412491
102antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.76412491
103negative thymic T cell selection (GO:0045060)2.74672691
104production of molecular mediator involved in inflammatory response (GO:0002532)2.74544661
105negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.74396599
106respiratory burst (GO:0045730)2.72948400
107positive regulation of interleukin-2 production (GO:0032743)2.72842760
108negative T cell selection (GO:0043383)2.72816760
109regulation of mast cell activation (GO:0033003)2.71740863
110regulation of interleukin-12 production (GO:0032655)2.71694619
111positive regulation of T-helper 1 type immune response (GO:0002827)2.70228448
112negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.69512773
113interferon-gamma-mediated signaling pathway (GO:0060333)2.68884322
114iron ion import (GO:0097286)2.68685429
115regulation of germinal center formation (GO:0002634)2.68338624
116regulation of mast cell activation involved in immune response (GO:0033006)2.67693809
117hepatocyte apoptotic process (GO:0097284)2.67422391
118JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.67203476
119positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.67087512
120leukocyte mediated cytotoxicity (GO:0001909)2.66370315
121regulation of NF-kappaB import into nucleus (GO:0042345)2.65891261
122leukocyte degranulation (GO:0043299)2.65123155
123regulation of alpha-beta T cell proliferation (GO:0046640)2.64842782
124negative regulation of protein autophosphorylation (GO:0031953)2.64832403
125detection of molecule of bacterial origin (GO:0032490)2.64222907
126regulation of leukocyte degranulation (GO:0043300)2.64043307
127regulation of myeloid leukocyte mediated immunity (GO:0002886)2.63896597
128negative regulation of glycoprotein biosynthetic process (GO:0010561)2.63013580
129defense response to protozoan (GO:0042832)2.63003065
130regulation of T-helper 1 cell differentiation (GO:0045625)2.62745979
131myeloid dendritic cell differentiation (GO:0043011)2.62697389
132T cell activation involved in immune response (GO:0002286)2.62391137
133negative regulation of adaptive immune response (GO:0002820)2.61967752
134leukocyte cell-cell adhesion (GO:0007159)2.60949686
135regulation of chronic inflammatory response (GO:0002676)2.60779138
136positive regulation of alpha-beta T cell proliferation (GO:0046641)2.60531319
137positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.60434179
138positive thymic T cell selection (GO:0045059)2.59951403
139positive regulation of interleukin-6 production (GO:0032755)2.59795252
140response to type I interferon (GO:0034340)2.59740744
141regulation of B cell differentiation (GO:0045577)2.58726242
142reactive oxygen species biosynthetic process (GO:1903409)2.58536090
143response to protozoan (GO:0001562)2.58461727
144surfactant homeostasis (GO:0043129)2.58306313
145type I interferon signaling pathway (GO:0060337)2.58189351
146cellular response to type I interferon (GO:0071357)2.58189351
147regulation of T cell tolerance induction (GO:0002664)2.57681922
148detection of external biotic stimulus (GO:0098581)2.56491181
149positive regulation of toll-like receptor signaling pathway (GO:0034123)2.55396400
150regulation of interleukin-17 production (GO:0032660)2.54049049
151B cell mediated immunity (GO:0019724)2.54001106
152positive regulation of type 2 immune response (GO:0002830)2.53918857
153regulation of prostaglandin secretion (GO:0032306)2.53817758
154monocyte chemotaxis (GO:0002548)2.52726573
155intestinal epithelial cell development (GO:0060576)2.52135050
156positive regulation of T-helper cell differentiation (GO:0045624)2.51811900
157regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.51769623
158regulation of antigen processing and presentation (GO:0002577)2.51156085
159regulation of heterotypic cell-cell adhesion (GO:0034114)2.50637437
160myeloid dendritic cell activation (GO:0001773)2.50432468
161regulation of interferon-beta biosynthetic process (GO:0045357)2.49896294

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.86350545
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.82664955
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.57283603
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.45062236
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.46015498
6RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.45001065
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.27526654
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.02814370
9IRF8_27001747_Chip-Seq_BMDM_Mouse2.99300598
10* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.99129626
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.98447190
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.98034292
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.96033267
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.88253571
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.73355038
16NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.69997946
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.58778865
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.56408045
19STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.53096390
20STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.49009995
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.32291761
22ESR1_20079471_ChIP-ChIP_T-47D_Human2.27594586
23STAT4_19710469_ChIP-ChIP_TH1__Mouse2.11654926
24SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.11426151
25SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.89100056
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.77301474
27ESR1_21235772_ChIP-Seq_MCF-7_Human1.76173342
28* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.76113976
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73723635
30VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.67539237
31E2F7_22180533_ChIP-Seq_HELA_Human1.64421176
32* MYB_26560356_Chip-Seq_TH2_Human1.64117893
33SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.62993643
34SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.62993643
35CDX2_20551321_ChIP-Seq_CACO-2_Human1.60687632
36NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.56437995
37* SPI1_23547873_ChIP-Seq_NB4_Human1.53225221
38FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.51624188
39PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.51319973
40FOXO3_23340844_ChIP-Seq_DLD1_Human1.50468833
41GATA1_19941826_ChIP-Seq_K562_Human1.50439921
42* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.49985223
43* GATA2_19941826_ChIP-Seq_K562_Human1.45836260
44BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.44422975
45ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.44259820
46GATA6_25053715_ChIP-Seq_YYC3_Human1.44146723
47KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.43686731
48KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.43686731
49KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.43686731
50* GATA4_25053715_ChIP-Seq_YYC3_Human1.43072156
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.42131491
52FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.41581779
53RUNX_20019798_ChIP-Seq_JUKART_Human1.39826725
54MYB_26560356_Chip-Seq_TH1_Human1.39702552
55HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35971423
56* MAF_26560356_Chip-Seq_TH1_Human1.35547275
57RUNX1_22412390_ChIP-Seq_EML_Mouse1.34857702
58FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.32370732
59* SOX2_20726797_ChIP-Seq_SW620_Human1.31357671
60CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.30823274
61SCL_19346495_ChIP-Seq_HPC-7_Human1.30130152
62PU_27001747_Chip-Seq_BMDM_Mouse1.29918467
63PPAR_26484153_Chip-Seq_NCI-H1993_Human1.28428273
64AHR_22903824_ChIP-Seq_MCF-7_Human1.27915875
65TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27371975
66ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26981487
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.26604705
68LXR_22158963_ChIP-Seq_LIVER_Mouse1.26055247
69GATA2_21666600_ChIP-Seq_HMVEC_Human1.25636851
70ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24993245
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.24816075
72* VDR_24763502_ChIP-Seq_THP-1_Human1.22842109
73* GATA1_19941827_ChIP-Seq_MEL_Mouse1.22664657
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22551074
75CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22052218
76EGR1_23403033_ChIP-Seq_LIVER_Mouse1.19331497
77* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.17678696
78* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17656037
79RXR_22158963_ChIP-Seq_LIVER_Mouse1.16947775
80VDR_24787735_ChIP-Seq_THP-1_Human1.16032813
81PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15572561
82PPARA_22158963_ChIP-Seq_LIVER_Mouse1.15233819
83TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.14894451
84SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.12817769
85GATA1_22025678_ChIP-Seq_K562_Human1.11153277
86GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10866138
87GATA3_24758297_ChIP-Seq_MCF-7_Human1.07868991
88RACK7_27058665_Chip-Seq_MCF-7_Human1.07580485
89CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.03975062
90GATA2_22383799_ChIP-Seq_G1ME_Mouse1.03486844
91P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02515518
92TCF7_22412390_ChIP-Seq_EML_Mouse1.02334865
93MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.01529404
94* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01413604
95KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01162079
96TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00960256
97* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00777094
98SPI1_23127762_ChIP-Seq_K562_Human1.00668188
99CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00383258
100* GATA3_27048872_Chip-Seq_THYMUS_Human0.99996867
101ARNT_22903824_ChIP-Seq_MCF-7_Human0.99340894
102SMRT_27268052_Chip-Seq_Bcells_Human0.98970732
103GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98899461
104RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98823715
105TP63_19390658_ChIP-ChIP_HaCaT_Human0.98164075
106RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97855859
107SALL4_18804426_ChIP-ChIP_XEN_Mouse0.96548919
108UTX_26944678_Chip-Seq_JUKART_Human0.94989279
109* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94340119
110* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.94317301
111* MAF_26560356_Chip-Seq_TH2_Human0.93689637
112PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89542352
113SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88726225
114ELK3_25401928_ChIP-Seq_HUVEC_Human0.88531626
115CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87963470
116SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87541556
117* ATF3_27146783_Chip-Seq_COLON_Human0.87204345
118NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.85379804
119* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85339170
120ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.84238302
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.83831299
122STAT3_1855785_ChIP-Seq_MESCs_Mouse0.83082349
123NOTCH1_21737748_ChIP-Seq_TLL_Human0.83017264
124NCOR1_26117541_ChIP-Seq_K562_Human0.82656534
125* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.82409356
126LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.82364782
127VDR_21846776_ChIP-Seq_THP-1_Human0.82166665
128GATA3_26560356_Chip-Seq_TH2_Human0.81774890
129* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.80993086
130* KLF5_25053715_ChIP-Seq_YYC3_Human0.80036332
131UBF1/2_26484160_Chip-Seq_HMECs_Human0.79417113

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009785_altered_susceptibility_to3.36321570
2MP0001835_abnormal_antigen_presentation3.06745375
3MP0003436_decreased_susceptibility_to2.83499234
4MP0002148_abnormal_hypersensitivity_rea2.73164291
5MP0003724_increased_susceptibility_to2.62513718
6MP0004947_skin_inflammation2.52229772
7MP0003303_peritoneal_inflammation2.49578575
8MP0000685_abnormal_immune_system2.44493907
9MP0005000_abnormal_immune_tolerance2.43370441
10MP0002419_abnormal_innate_immunity2.41114815
11MP0005025_abnormal_response_to2.40037503
12MP0005387_immune_system_phenotype2.32940806
13MP0001790_abnormal_immune_system2.32940806
14MP0010234_abnormal_vibrissa_follicle2.23124017
15MP0002254_reproductive_system_inflammat2.19820670
16MP0006082_CNS_inflammation2.19089982
17MP0010155_abnormal_intestine_physiology2.14819222
18MP0002452_abnormal_antigen_presenting2.13706226
19MP0004782_abnormal_surfactant_physiolog2.04857778
20MP0002723_abnormal_immune_serum2.00866786
21MP0009278_abnormal_bone_marrow1.99185730
22MP0004381_abnormal_hair_follicle1.99161043
23MP0002006_tumorigenesis1.97503705
24MP0001800_abnormal_humoral_immune1.96990044
25MP0010352_gastrointestinal_tract_polyps1.95586416
26MP0002405_respiratory_system_inflammati1.91709213
27MP0005671_abnormal_response_to1.87835369
28MP0009764_decreased_sensitivity_to1.86711556
29MP0002277_abnormal_respiratory_mucosa1.86074764
30MP0003453_abnormal_keratinocyte_physiol1.85871119
31MP0001819_abnormal_immune_cell1.82955382
32MP0005310_abnormal_salivary_gland1.81169359
33MP0002420_abnormal_adaptive_immunity1.78431638
34MP0005083_abnormal_biliary_tract1.76718463
35MP0003448_altered_tumor_morphology1.72861629
36MP0005167_abnormal_blood-brain_barrier1.68641757
37MP0001845_abnormal_inflammatory_respons1.67790832
38MP0001873_stomach_inflammation1.67329524
39MP0005076_abnormal_cell_differentiation1.65521424
40MP0003300_gastrointestinal_ulcer1.61697474
41MP0004510_myositis1.59086459
42MP0000858_altered_metastatic_potential1.57864396
43MP0004883_abnormal_blood_vessel1.57543875
44MP0009333_abnormal_splenocyte_physiolog1.54117974
45MP0005464_abnormal_platelet_physiology1.53441741
46MP0002138_abnormal_hepatobiliary_system1.52434689
47MP0001545_abnormal_hematopoietic_system1.50972217
48MP0005397_hematopoietic_system_phenotyp1.50972217
49MP0004264_abnormal_extraembryonic_tissu1.50300284
50MP0001533_abnormal_skeleton_physiology1.48389900
51MP0002009_preneoplasia1.46062825
52MP0001853_heart_inflammation1.45383446
53MP0001666_abnormal_nutrient_absorption1.44168200
54MP0003941_abnormal_skin_development1.36239257
55MP0000490_abnormal_crypts_of1.36160983
56MP0003172_abnormal_lysosome_physiology1.29805725
57MP0000716_abnormal_immune_system1.29342652
58MP0002796_impaired_skin_barrier1.29082381
59MP0003566_abnormal_cell_adhesion1.27140876
60MP0003828_pulmonary_edema1.25204248
61MP0001216_abnormal_epidermal_layer1.24976913
62MP0008469_abnormal_protein_level1.24401631
63MP0005377_hearing/vestibular/ear_phenot1.23846218
64MP0003878_abnormal_ear_physiology1.23846218
65MP0004185_abnormal_adipocyte_glucose1.22568498
66MP0003866_abnormal_defecation1.22350637
67MP0003656_abnormal_erythrocyte_physiolo1.20341329
68MP0002398_abnormal_bone_marrow1.19892856
69MP0003191_abnormal_cellular_cholesterol1.17580989
70MP0002166_altered_tumor_susceptibility1.17189647
71MP0001765_abnormal_ion_homeostasis1.16492315
72MP0005085_abnormal_gallbladder_physiolo1.12331222
73MP0002098_abnormal_vibrissa_morphology1.11507648
74MP0002132_abnormal_respiratory_system1.11013391
75MP0010678_abnormal_skin_adnexa1.08565698
76MP0005058_abnormal_lysosome_morphology1.08182643
77MP0002998_abnormal_bone_remodeling1.07929485
78MP0003763_abnormal_thymus_physiology1.07070986
79MP0005166_decreased_susceptibility_to1.06744568
80MP0000343_altered_response_to1.06591419
81MP0002429_abnormal_blood_cell1.05234659
82MP0003045_fibrosis1.03800411
83MP0003693_abnormal_embryo_hatching1.02691936
84MP0002396_abnormal_hematopoietic_system1.01512004
85MP0000703_abnormal_thymus_morphology1.01460618
86MP0002722_abnormal_immune_system1.00995919
87MP0005365_abnormal_bile_salt0.99173047
88MP0000627_abnormal_mammary_gland0.98873215
89MP0000383_abnormal_hair_follicle0.98768163
90MP0008004_abnormal_stomach_pH0.98455425
91MP0009840_abnormal_foam_cell0.95948792
92MP0000689_abnormal_spleen_morphology0.95768881
93MP0005451_abnormal_body_composition0.94550951
94MP0001881_abnormal_mammary_gland0.93092113
95MP0008995_early_reproductive_senescence0.92100298
96MP0003646_muscle_fatigue0.91314224
97MP0003075_altered_response_to0.90594432
98MP0005164_abnormal_response_to0.87593760
99MP0010307_abnormal_tumor_latency0.87051841
100MP0005023_abnormal_wound_healing0.86731273
101MP0002693_abnormal_pancreas_physiology0.86370076
102MP0005075_abnormal_melanosome_morpholog0.85824574
103MP0003186_abnormal_redox_activity0.83716665
104MP0002136_abnormal_kidney_physiology0.83707844
105MP0008057_abnormal_DNA_replication0.81948439
106MP0003252_abnormal_bile_duct0.81902409
107MP0005390_skeleton_phenotype0.81425449
108MP0003183_abnormal_peptide_metabolism0.81068831
109MP0008260_abnormal_autophagy0.80583742
110MP0009643_abnormal_urine_homeostasis0.78480369
111MP0001663_abnormal_digestive_system0.77254552
112MP0002877_abnormal_melanocyte_morpholog0.76458559
113MP0001851_eye_inflammation0.75878061
114MP0001191_abnormal_skin_condition0.75615003
115MP0003638_abnormal_response/metabolism_0.75513350
116MP0002060_abnormal_skin_morphology0.75362506
117MP0000470_abnormal_stomach_morphology0.75089367
118MP0000371_diluted_coat_color0.74774248
119MP0000427_abnormal_hair_cycle0.74728552
120MP0004484_altered_response_of0.73893310
121MP0000465_gastrointestinal_hemorrhage0.73476794
122MP0009765_abnormal_xenobiotic_induced0.73090398
123MP0005501_abnormal_skin_physiology0.73024048
124MP0004019_abnormal_vitamin_homeostasis0.72227240
125MP0009763_increased_sensitivity_to0.72128721
126MP0000015_abnormal_ear_pigmentation0.71968149
127MP0000678_abnormal_parathyroid_gland0.71756597
128MP0000609_abnormal_liver_physiology0.66588859
129MP0000377_abnormal_hair_follicle0.65803163

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.00438698
2Recurrent abscess formation (HP:0002722)5.45050258
3Recurrent bacterial skin infections (HP:0005406)4.92860623
4Retrobulbar optic neuritis (HP:0100654)4.71562488
5Optic neuritis (HP:0100653)4.71562488
6Orchitis (HP:0100796)4.70331502
7Mediastinal lymphadenopathy (HP:0100721)4.34247285
8Stomatitis (HP:0010280)4.20439108
9Myositis (HP:0100614)4.14803511
10Recurrent gram-negative bacterial infections (HP:0005420)4.13016265
11Pustule (HP:0200039)4.12273316
12Abnormality of macrophages (HP:0004311)4.06125170
13Interstitial pulmonary disease (HP:0006530)3.93747519
14Autoimmune thrombocytopenia (HP:0001973)3.63499460
15Recurrent fungal infections (HP:0002841)3.63018819
16Gingivitis (HP:0000230)3.62201441
17Elevated erythrocyte sedimentation rate (HP:0003565)3.60291942
18Prostate neoplasm (HP:0100787)3.36987197
19Abnormal delayed hypersensitivity skin test (HP:0002963)3.21375256
20Vasculitis (HP:0002633)3.20213016
21Periodontitis (HP:0000704)3.14485509
22Cheilitis (HP:0100825)2.99149173
23Chronic obstructive pulmonary disease (HP:0006510)2.96073932
24Obstructive lung disease (HP:0006536)2.96073932
25Recurrent skin infections (HP:0001581)2.94957676
26Keratoconjunctivitis sicca (HP:0001097)2.93188415
27Keratoconjunctivitis (HP:0001096)2.92975503
28Premature loss of primary teeth (HP:0006323)2.90822171
29Pulmonary infiltrates (HP:0002113)2.88255195
30Thick nail (HP:0001805)2.85990647
31Increased IgE level (HP:0003212)2.85174366
32Malnutrition (HP:0004395)2.79967020
33Neoplasm of the tracheobronchial system (HP:0100552)2.77275796
34Alveolar cell carcinoma (HP:0006519)2.76091134
35Absent/shortened dynein arms (HP:0200106)2.70665204
36Dynein arm defect of respiratory motile cilia (HP:0012255)2.70665204
37Vacuolated lymphocytes (HP:0001922)2.67272854
38Recurrent viral infections (HP:0004429)2.64760623
39Bronchiectasis (HP:0002110)2.64182789
40Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.62853081
41T lymphocytopenia (HP:0005403)2.60994839
42Chronic bronchitis (HP:0004469)2.56703538
43Spontaneous hematomas (HP:0007420)2.55547717
44Bronchitis (HP:0012387)2.53822676
45Recurrent bronchitis (HP:0002837)2.51842084
46Hemoptysis (HP:0002105)2.47314794
47Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.46986325
48Increased IgM level (HP:0003496)2.45846883
49Chronic mucocutaneous candidiasis (HP:0002728)2.45561203
50Recurrent cutaneous fungal infections (HP:0011370)2.45561203
51Tetraparesis (HP:0002273)2.44779620
52Anorexia (HP:0002039)2.44705891
53Urticaria (HP:0001025)2.43112456
54Arterial thrombosis (HP:0004420)2.42987235
55Hypochromic anemia (HP:0001931)2.41414269
56Decreased circulating renin level (HP:0003351)2.40568562
57Hypochromic microcytic anemia (HP:0004840)2.40546106
58Chronic sinusitis (HP:0011109)2.38756720
59Plantar hyperkeratosis (HP:0007556)2.37931519
60Abnormal respiratory epithelium morphology (HP:0012253)2.34195166
61Abnormal respiratory motile cilium morphology (HP:0005938)2.34195166
62Chest pain (HP:0100749)2.33641995
63Gastrointestinal infarctions (HP:0005244)2.31722368
64Hematochezia (HP:0002573)2.31650842
65Leukocytosis (HP:0001974)2.30879181
66Abnormality of T cells (HP:0002843)2.27871214
67Recurrent sinusitis (HP:0011108)2.26472755
68Abnormal ciliary motility (HP:0012262)2.24533958
69Abnormal respiratory motile cilium physiology (HP:0012261)2.24331489
70Inflammation of the large intestine (HP:0002037)2.23621686
71Esophageal varix (HP:0002040)2.23014527
72Osteolytic defects of the phalanges of the hand (HP:0009771)2.21591777
73Osteolytic defects of the hand bones (HP:0009699)2.21591777
74Autoimmune hemolytic anemia (HP:0001890)2.18794689
75Petechiae (HP:0000967)2.16380043
76Onycholysis (HP:0001806)2.16228346
77Prolonged bleeding time (HP:0003010)2.15714400
78Gangrene (HP:0100758)2.15562965
79Palmar hyperkeratosis (HP:0010765)2.14503269
80Episodic fever (HP:0001954)2.13049806
81Pulmonary embolism (HP:0002204)2.13031277
82Increased neuronal autofluorescent lipopigment (HP:0002074)2.09473966
83Palmoplantar hyperkeratosis (HP:0000972)2.09429805
84Lip pit (HP:0100267)2.08308714
85Meningitis (HP:0001287)2.07629125
86Rhinitis (HP:0012384)2.06927156
87Gastrointestinal inflammation (HP:0004386)2.05862652
88Osteomyelitis (HP:0002754)2.04492202
89Stomach cancer (HP:0012126)2.03687136
90Cellulitis (HP:0100658)2.02810524
91Hypergammaglobulinemia (HP:0010702)2.00201284
92Chronic otitis media (HP:0000389)1.99838809
93Hyperkalemia (HP:0002153)1.98302717
94Increased cerebral lipofuscin (HP:0011813)1.98270065
95Skin ulcer (HP:0200042)1.97871735
96Ventricular fibrillation (HP:0001663)1.97611293
97Anhidrosis (HP:0000970)1.97057498
98Granulocytopenia (HP:0001913)1.91724928
99Colitis (HP:0002583)1.91562432
100Peritonitis (HP:0002586)1.91295591
101Chronic diarrhea (HP:0002028)1.89368396
102IgA deficiency (HP:0002720)1.89030431
103Abnormality of the pericardium (HP:0001697)1.88998516
104Amyloidosis (HP:0011034)1.88285347
105Basal ganglia calcification (HP:0002135)1.87601385
106Microcytic anemia (HP:0001935)1.87088820
107Abnormality of the nasal septum (HP:0000419)1.86354602
108Gingival bleeding (HP:0000225)1.85045709
109Curly hair (HP:0002212)1.83406010
110Abnormality of the gastric mucosa (HP:0004295)1.83244066
111Milia (HP:0001056)1.83179438
112Increased CSF protein (HP:0002922)1.82924404
113Micronodular cirrhosis (HP:0001413)1.82697597
114Abnormality of renin-angiotensin system (HP:0000847)1.81510418
115Recurrent pneumonia (HP:0006532)1.81265090
116Acne (HP:0001061)1.81074329
117Abnormality of the prostate (HP:0008775)1.80660590
118Recurrent otitis media (HP:0000403)1.80311617
119Abnormality of the pleura (HP:0002103)1.79959950
120Abnormality of T cell number (HP:0011839)1.79282178
121Hydroxyprolinuria (HP:0003080)1.79261869
122Abnormality of proline metabolism (HP:0010907)1.79261869
123Encephalitis (HP:0002383)1.78435664
124Blepharitis (HP:0000498)1.76093509
125Alopecia of scalp (HP:0002293)1.74829745
126Eosinophilia (HP:0001880)1.74205647
127Right ventricular cardiomyopathy (HP:0011663)1.74076123
128Bone pain (HP:0002653)1.73828088
129Nasal polyposis (HP:0100582)1.72343427
130Abnormality of the fingertips (HP:0001211)1.70934159
131Myocardial infarction (HP:0001658)1.70375732
132Abnormality of the nasal mucosa (HP:0000433)1.68171243
133Abnormality of small intestinal villus morphology (HP:0011472)1.66566730
134Villous atrophy (HP:0011473)1.66566730
135Rectal prolapse (HP:0002035)1.66543146
136Hyperactive renin-angiotensin system (HP:0000841)1.66301985
137Porencephaly (HP:0002132)1.65571554
138Joint swelling (HP:0001386)1.64365045
139Abnormality of chloride homeostasis (HP:0011422)1.64243299
140Persistence of primary teeth (HP:0006335)1.64166692
141Arthralgia (HP:0002829)1.63403481
142Abnormality of eosinophils (HP:0001879)1.63034519
143Abnormality of T cell physiology (HP:0011840)1.62773287
144Polyneuropathy (HP:0001271)1.62716269

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.79809545
2IRAK33.92083535
3MST43.33603500
4TBK12.77018929
5IRAK42.64096246
6EPHA22.63552240
7TXK2.61064903
8IKBKB2.47317206
9RIPK42.40740784
10IKBKE2.37521016
11MAP4K12.35513543
12JAK32.26097045
13CHUK2.09112448
14BLK2.06383649
15STK102.06292233
16TYK21.99818185
17CDK121.94971901
18TAOK31.91325247
19MST1R1.62207322
20PBK1.53852175
21EPHB11.50032020
22CSK1.42297362
23ERN11.40253424
24MAP3K31.37093527
25RPS6KA41.36484708
26STK31.34299617
27PIM11.34158902
28NUAK11.30434336
29AKT31.30361196
30JAK11.29755786
31FER1.28611485
32FES1.25454582
33TNK21.25090648
34PIM21.22282785
35MAP3K101.19266440
36BMX1.17808385
37PRPF4B1.15985932
38ZAP701.14332219
39TEC1.10933589
40MAP3K111.10674404
41MAPK151.06223103
42MARK31.03622353
43RIPK11.01196976
44OXSR11.00914395
45MAP3K70.99783196
46FGFR30.99617566
47LATS10.98916299
48SIK30.95405331
49EIF2AK20.94529782
50STK240.90351680
51SGK30.90300128
52PRKG20.89437919
53MAP2K20.89346079
54EPHA30.89246176
55BTK0.87769513
56NEK90.87623371
57MARK20.86971272
58SGK20.85280314
59FRK0.84755094
60MAP2K60.84639599
61MATK0.84533774
62TRPM70.84231270
63NLK0.84165730
64TRIB30.81412680
65HIPK20.81324729
66PTK60.81175534
67STK390.79476651
68HCK0.78369569
69MAP3K60.78340800
70FGFR40.78192982
71STK40.77731207
72KSR20.77553318
73MAP2K30.77137761
74MAP3K130.77049915
75ACVR1B0.75758705
76RPS6KB20.75385751
77PRKD20.75188238
78LRRK20.74190755
79GRK10.73744774
80JAK20.73139394
81PDPK10.73043584
82WNK10.70534926
83PDK10.68689039
84LCK0.65512461
85PRKCQ0.64366351
86PKN20.63876623
87ITK0.63858597
88CDK60.62230532
89FGR0.61686489
90IRAK10.60037898
91TGFBR20.58572977
92ERBB40.56200660
93YES10.55906963
94MAP3K50.55418026
95LYN0.54602955
96TAOK10.54246832
97MAPKAPK20.54117044
98SYK0.54104130
99ERBB20.53833155
100MAP3K120.52602472
101KIT0.52224461
102PAK30.52012838
103MAPKAPK30.51778805
104BMPR20.51452687
105RET0.50798326
106TLK10.50782035
107ABL10.50428504
108PIK3CG0.49581202
109PRKCI0.49537029
110PRKAA20.48461780
111MAP3K80.48429669
112RPS6KA20.46100089
113PAK40.45949642
114EPHB20.45506054
115SGK4940.45421011
116SGK2230.45421011
117EGFR0.45028517
118RPS6KL10.44773676
119RPS6KC10.44773676
120RPS6KA60.44085491
121STK110.43856452
122STK380.43368242
123TAOK20.42992995
124PRKCD0.42205273
125NEK20.41467393
126ZAK0.41362919
127MAP3K10.40301316
128GRK60.40011732
129RPS6KA10.38792439
130PDGFRB0.37834078
131MAP3K20.33218115
132STK38L0.32828967
133CSF1R0.32281177
134ABL20.31944550
135SIK10.31698811
136GSK3A0.31532186
137PTK20.31370816
138PLK40.31048245
139NME20.30591771
140MELK0.30340590

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.21196924
2Graft-versus-host disease_Homo sapiens_hsa053323.14224175
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.98770165
4NOD-like receptor signaling pathway_Homo sapiens_hsa046212.83148165
5Legionellosis_Homo sapiens_hsa051342.63793126
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.62331850
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.35277439
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.29522728
9Allograft rejection_Homo sapiens_hsa053302.26852152
10TNF signaling pathway_Homo sapiens_hsa046682.17565114
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.11950592
12Osteoclast differentiation_Homo sapiens_hsa043802.02791674
13Measles_Homo sapiens_hsa051622.00824595
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.96400135
15Pertussis_Homo sapiens_hsa051331.90354921
16Malaria_Homo sapiens_hsa051441.87707408
17Rheumatoid arthritis_Homo sapiens_hsa053231.86912031
18Influenza A_Homo sapiens_hsa051641.80423268
19Staphylococcus aureus infection_Homo sapiens_hsa051501.79407300
20Hematopoietic cell lineage_Homo sapiens_hsa046401.76365879
21Tuberculosis_Homo sapiens_hsa051521.76333183
22Type I diabetes mellitus_Homo sapiens_hsa049401.71895029
23African trypanosomiasis_Homo sapiens_hsa051431.69725924
24Toxoplasmosis_Homo sapiens_hsa051451.63596938
25Herpes simplex infection_Homo sapiens_hsa051681.60908510
26Asthma_Homo sapiens_hsa053101.60559708
27Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.49736140
28Salmonella infection_Homo sapiens_hsa051321.45703670
29Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.44134325
30Apoptosis_Homo sapiens_hsa042101.42633044
31Jak-STAT signaling pathway_Homo sapiens_hsa046301.42128096
32Carbohydrate digestion and absorption_Homo sapiens_hsa049731.29418242
33Mineral absorption_Homo sapiens_hsa049781.29223242
34Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.25166092
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.23852265
36Antigen processing and presentation_Homo sapiens_hsa046121.23280106
37Hepatitis C_Homo sapiens_hsa051601.20997204
38Pancreatic secretion_Homo sapiens_hsa049721.15821591
39AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.09261441
40alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.02925747
41B cell receptor signaling pathway_Homo sapiens_hsa046620.99493736
42Amoebiasis_Homo sapiens_hsa051460.99149089
43Shigellosis_Homo sapiens_hsa051310.99096186
44Autoimmune thyroid disease_Homo sapiens_hsa053200.98948234
45Small cell lung cancer_Homo sapiens_hsa052220.96949500
46Linoleic acid metabolism_Homo sapiens_hsa005910.96873781
47Hepatitis B_Homo sapiens_hsa051610.96419000
48Primary immunodeficiency_Homo sapiens_hsa053400.93997678
49Vitamin digestion and absorption_Homo sapiens_hsa049770.91978250
50Chemokine signaling pathway_Homo sapiens_hsa040620.91071129
51T cell receptor signaling pathway_Homo sapiens_hsa046600.89112895
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.88152511
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87789482
54Acute myeloid leukemia_Homo sapiens_hsa052210.87447663
55Type II diabetes mellitus_Homo sapiens_hsa049300.85820097
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85466300
57Non-small cell lung cancer_Homo sapiens_hsa052230.85411321
58Lysosome_Homo sapiens_hsa041420.84280052
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81607813
60Renin-angiotensin system_Homo sapiens_hsa046140.80082299
61p53 signaling pathway_Homo sapiens_hsa041150.78181199
62Glycerophospholipid metabolism_Homo sapiens_hsa005640.78105557
63Phagosome_Homo sapiens_hsa041450.78099110
64Renal cell carcinoma_Homo sapiens_hsa052110.77267696
65Inositol phosphate metabolism_Homo sapiens_hsa005620.77195723
66Adherens junction_Homo sapiens_hsa045200.75493757
67Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74371315
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74075545
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73686366
70Sulfur metabolism_Homo sapiens_hsa009200.72586770
71Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69856439
72Epstein-Barr virus infection_Homo sapiens_hsa051690.69243632
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67303658
74Choline metabolism in cancer_Homo sapiens_hsa052310.66780953
75Other glycan degradation_Homo sapiens_hsa005110.66142697
76Viral myocarditis_Homo sapiens_hsa054160.66041271
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.65744401
78VEGF signaling pathway_Homo sapiens_hsa043700.65054868
79Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64874000
80Sphingolipid metabolism_Homo sapiens_hsa006000.63524378
81Prolactin signaling pathway_Homo sapiens_hsa049170.63250860
82Endometrial cancer_Homo sapiens_hsa052130.62567779
83Chronic myeloid leukemia_Homo sapiens_hsa052200.61984314
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57895465
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57006242
86Glycerolipid metabolism_Homo sapiens_hsa005610.55755964
87* Endocytosis_Homo sapiens_hsa041440.55637429
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55470020
89MicroRNAs in cancer_Homo sapiens_hsa052060.54750012
90Starch and sucrose metabolism_Homo sapiens_hsa005000.54585560
91Protein digestion and absorption_Homo sapiens_hsa049740.53403737
92Chemical carcinogenesis_Homo sapiens_hsa052040.53381691
93Ether lipid metabolism_Homo sapiens_hsa005650.52812971
94Thyroid cancer_Homo sapiens_hsa052160.51802745
95Viral carcinogenesis_Homo sapiens_hsa052030.51711727
96Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50405351
97mTOR signaling pathway_Homo sapiens_hsa041500.49290122
98GnRH signaling pathway_Homo sapiens_hsa049120.48415052
99Pancreatic cancer_Homo sapiens_hsa052120.48411728
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46849963
101HTLV-I infection_Homo sapiens_hsa051660.46813026
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46157506
103HIF-1 signaling pathway_Homo sapiens_hsa040660.44904043
104Histidine metabolism_Homo sapiens_hsa003400.44500280
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.44289015
106Caffeine metabolism_Homo sapiens_hsa002320.41131383
107Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41083293
108FoxO signaling pathway_Homo sapiens_hsa040680.38770493
109Proteoglycans in cancer_Homo sapiens_hsa052050.37405576
110Notch signaling pathway_Homo sapiens_hsa043300.37217297
111Folate biosynthesis_Homo sapiens_hsa007900.37135104
112Fat digestion and absorption_Homo sapiens_hsa049750.36764655
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36443305
114Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34163569
115Arachidonic acid metabolism_Homo sapiens_hsa005900.33722774
116ABC transporters_Homo sapiens_hsa020100.32592373
117Dorso-ventral axis formation_Homo sapiens_hsa043200.32547367
118Retinol metabolism_Homo sapiens_hsa008300.31342720
119Prostate cancer_Homo sapiens_hsa052150.30242341
120Platelet activation_Homo sapiens_hsa046110.30219222
121Insulin resistance_Homo sapiens_hsa049310.30071070
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.28254281
123Fructose and mannose metabolism_Homo sapiens_hsa000510.28223359
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27493253
125Galactose metabolism_Homo sapiens_hsa000520.27080165
126Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26924288
127Glycosaminoglycan degradation_Homo sapiens_hsa005310.26825534
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26813014

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