RAB11FIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)5.11906247
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.10645211
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.87825028
4neuron cell-cell adhesion (GO:0007158)4.73428475
5vocalization behavior (GO:0071625)4.71299895
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.66929260
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.51026408
8synaptic vesicle maturation (GO:0016188)4.48355790
9ionotropic glutamate receptor signaling pathway (GO:0035235)4.45524095
10synaptic vesicle exocytosis (GO:0016079)4.45472173
11protein localization to synapse (GO:0035418)4.41034448
12regulation of glutamate receptor signaling pathway (GO:1900449)4.32093425
13regulation of synaptic vesicle exocytosis (GO:2000300)4.23527165
14exploration behavior (GO:0035640)4.21918988
15layer formation in cerebral cortex (GO:0021819)4.09148204
16glutamate secretion (GO:0014047)4.05554438
17glutamate receptor signaling pathway (GO:0007215)4.04181932
18neuron recognition (GO:0008038)3.98148178
19dendritic spine morphogenesis (GO:0060997)3.96759998
20presynaptic membrane assembly (GO:0097105)3.90433204
21regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.78936377
22neuronal action potential propagation (GO:0019227)3.77058713
23regulation of long-term neuronal synaptic plasticity (GO:0048169)3.76637077
24regulation of synaptic vesicle transport (GO:1902803)3.73669029
25synaptic transmission, glutamatergic (GO:0035249)3.72377989
26regulation of neuronal synaptic plasticity (GO:0048168)3.70945734
27axonal fasciculation (GO:0007413)3.68214724
28neuron-neuron synaptic transmission (GO:0007270)3.62788111
29synaptic vesicle docking involved in exocytosis (GO:0016081)3.62719628
30transmission of nerve impulse (GO:0019226)3.59071207
31regulation of dendritic spine morphogenesis (GO:0061001)3.55451958
32presynaptic membrane organization (GO:0097090)3.53832192
33neural tube formation (GO:0001841)3.49336202
34regulation of excitatory postsynaptic membrane potential (GO:0060079)3.46969264
35dendrite morphogenesis (GO:0048813)3.46076200
36auditory behavior (GO:0031223)3.45563546
37neurotransmitter-gated ion channel clustering (GO:0072578)3.40822765
38neurotransmitter secretion (GO:0007269)3.39299197
39positive regulation of membrane potential (GO:0045838)3.38076057
40postsynaptic membrane organization (GO:0001941)3.37761416
41regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.31584700
42regulation of postsynaptic membrane potential (GO:0060078)3.31449540
43regulation of sarcomere organization (GO:0060297)3.30927202
44gamma-aminobutyric acid transport (GO:0015812)3.30164241
45regulation of synapse structural plasticity (GO:0051823)3.29917135
46long-term memory (GO:0007616)3.27985798
47establishment of nucleus localization (GO:0040023)3.27255663
48innervation (GO:0060384)3.24788558
49negative regulation of dendrite development (GO:2000171)3.17396687
50long-term synaptic potentiation (GO:0060291)3.15395751
51gamma-aminobutyric acid signaling pathway (GO:0007214)3.13182600
52protein targeting to Golgi (GO:0000042)3.12666960
53establishment of protein localization to Golgi (GO:0072600)3.10643709
54regulation of synaptic plasticity (GO:0048167)3.09376022
55regulation of synaptic transmission, glutamatergic (GO:0051966)3.08116803
56nucleus localization (GO:0051647)3.08111171
57olfactory bulb development (GO:0021772)3.07561794
58regulation of dendritic spine development (GO:0060998)3.06618457
59negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.05329126
60membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.04049124
61proline transport (GO:0015824)3.02050967
62synapse assembly (GO:0007416)3.01807042
63response to auditory stimulus (GO:0010996)3.00495034
64neuronal ion channel clustering (GO:0045161)3.00472588
65negative regulation of synaptic transmission, GABAergic (GO:0032229)3.00331755
66positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.94438707
67response to histamine (GO:0034776)2.93550780
68synaptic vesicle endocytosis (GO:0048488)2.92680132
69vesicle transport along microtubule (GO:0047496)2.92533623
70central nervous system projection neuron axonogenesis (GO:0021952)2.91734468
71cerebral cortex radially oriented cell migration (GO:0021799)2.90775752
72mechanosensory behavior (GO:0007638)2.90561284
73activation of protein kinase A activity (GO:0034199)2.90293143
74regulation of neurotransmitter secretion (GO:0046928)2.90125706
75synapse organization (GO:0050808)2.89840791
76positive regulation of synapse maturation (GO:0090129)2.89757243
77retrograde transport, vesicle recycling within Golgi (GO:0000301)2.89198313
78artery development (GO:0060840)2.88094749
79neurotransmitter transport (GO:0006836)2.88001046
80mating behavior (GO:0007617)2.87486811
81G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.87087471
82L-amino acid import (GO:0043092)2.86966451
83regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.86441571
84startle response (GO:0001964)2.85226227
85retinal ganglion cell axon guidance (GO:0031290)2.84966847
86learning (GO:0007612)2.84910912
87positive regulation of synaptic transmission, GABAergic (GO:0032230)2.84171360
88regulation of vesicle fusion (GO:0031338)2.83827855
89membrane depolarization (GO:0051899)2.83586498
90cytoplasmic mRNA processing body assembly (GO:0033962)2.82196911
91G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.80910955
92membrane hyperpolarization (GO:0060081)2.77477499
93pyrimidine nucleobase catabolic process (GO:0006208)2.77110971
94neuromuscular process controlling balance (GO:0050885)2.77096850
95chemosensory behavior (GO:0007635)2.76965764
96positive regulation of dendritic spine development (GO:0060999)2.76945345
97cell migration in hindbrain (GO:0021535)2.76741811
98cerebellar granule cell differentiation (GO:0021707)2.76682431
99retinal cone cell development (GO:0046549)2.75102795
100cerebellar Purkinje cell differentiation (GO:0021702)2.74410565
101prepulse inhibition (GO:0060134)2.73695625
102positive regulation of dendritic spine morphogenesis (GO:0061003)2.73082952
103detection of calcium ion (GO:0005513)2.72606103
104behavioral fear response (GO:0001662)2.72602221
105behavioral defense response (GO:0002209)2.72602221
106dendritic spine organization (GO:0097061)2.72459804
107inositol phosphate catabolic process (GO:0071545)2.71673199
108negative regulation of neurotransmitter transport (GO:0051589)2.70426180
109organelle transport along microtubule (GO:0072384)2.68149397
110dorsal/ventral axis specification (GO:0009950)2.67528844
111negative regulation of translation, ncRNA-mediated (GO:0040033)2.66976775
112regulation of translation, ncRNA-mediated (GO:0045974)2.66976775
113negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.66976775
114regulation of neurotransmitter transport (GO:0051588)2.65124224
115negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.65056076
116regulation of female receptivity (GO:0045924)2.64055814
117cellular potassium ion homeostasis (GO:0030007)2.62808180
118membrane depolarization during action potential (GO:0086010)2.61950855
119regulation of neurotransmitter levels (GO:0001505)2.61814524
120fear response (GO:0042596)2.61572878
121calcium ion-dependent exocytosis (GO:0017156)2.61178858
122intraspecies interaction between organisms (GO:0051703)2.59974332
123protein localization to Golgi apparatus (GO:0034067)2.56439647
124intraciliary transport (GO:0042073)2.55495139
125ribonucleoprotein complex disassembly (GO:0032988)2.55485863
126axon extension involved in axon guidance (GO:0048846)2.54803604
127neuron projection extension involved in neuron projection guidance (GO:1902284)2.54803604
128negative regulation of neurotransmitter secretion (GO:0046929)2.53559794
129regulation of growth hormone secretion (GO:0060123)2.52726645
130protein prenylation (GO:0018342)2.50331931
131prenylation (GO:0097354)2.50331931
132regulation of hexokinase activity (GO:1903299)2.48228183
133regulation of glucokinase activity (GO:0033131)2.48228183
134negative regulation of axon guidance (GO:1902668)2.47760109
135regulation of timing of cell differentiation (GO:0048505)2.46961112
136cornea development in camera-type eye (GO:0061303)2.46661208
137membrane assembly (GO:0071709)2.45954062
138behavioral response to nicotine (GO:0035095)2.45264143
139regulation of membrane repolarization (GO:0060306)2.43731013
140central nervous system neuron axonogenesis (GO:0021955)2.42951883
141magnesium ion transport (GO:0015693)2.41790281
142atrial cardiac muscle cell action potential (GO:0086014)2.41250701
143negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.40276686
144adult walking behavior (GO:0007628)2.40167958
145positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.39295443
146nonmotile primary cilium assembly (GO:0035058)2.38965731
147negative regulation of dendrite morphogenesis (GO:0050774)2.38672947
148regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.36077274
149gastrulation with mouth forming second (GO:0001702)2.34881293
150regulation of Rac protein signal transduction (GO:0035020)2.33978234
151negative regulation of potassium ion transmembrane transport (GO:1901380)2.33864731
152inositol phosphate dephosphorylation (GO:0046855)2.33538195
153phosphorylated carbohydrate dephosphorylation (GO:0046838)2.33538195
154organelle disassembly (GO:1903008)2.31740368
155axon extension (GO:0048675)2.31127610
156neuron fate determination (GO:0048664)2.30354891
157regulation of non-canonical Wnt signaling pathway (GO:2000050)2.30135416
158negative chemotaxis (GO:0050919)2.28474292
159plasma membrane repair (GO:0001778)2.28072393
160positive regulation of neuroblast proliferation (GO:0002052)2.27635272
161somite rostral/caudal axis specification (GO:0032525)2.27496292
162regulation of collateral sprouting (GO:0048670)2.26900908
163nucleobase catabolic process (GO:0046113)2.26329563
164mitotic sister chromatid cohesion (GO:0007064)2.25731985
165pre-miRNA processing (GO:0031054)2.25029303
166specification of organ identity (GO:0010092)2.24646986
167righting reflex (GO:0060013)2.24020258
168limb bud formation (GO:0060174)2.23832862
169peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.23745001

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.46746515
2GBX2_23144817_ChIP-Seq_PC3_Human3.64966348
3SALL1_21062744_ChIP-ChIP_HESCs_Human2.86345934
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.77565731
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.76969788
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71092878
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.47568390
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.38264869
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.38264869
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.37809987
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36332681
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.27771384
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.27002841
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26169255
15REST_21632747_ChIP-Seq_MESCs_Mouse2.23133207
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.23005001
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.22031231
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.20279496
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.12658606
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.11284574
21DROSHA_22980978_ChIP-Seq_HELA_Human2.10583875
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.02556597
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.02392464
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.00767069
25VDR_22108803_ChIP-Seq_LS180_Human1.98057849
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.97176256
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.96849490
28AR_21572438_ChIP-Seq_LNCaP_Human1.96297207
29TAF15_26573619_Chip-Seq_HEK293_Human1.94309080
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.93852268
31EWS_26573619_Chip-Seq_HEK293_Human1.93645905
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.93203366
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83661624
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.80069650
35SMAD4_21799915_ChIP-Seq_A2780_Human1.78547490
36FLI1_27457419_Chip-Seq_LIVER_Mouse1.76632820
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75165997
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.72547521
39REST_18959480_ChIP-ChIP_MESCs_Mouse1.65319096
40P300_19829295_ChIP-Seq_ESCs_Human1.63107958
41CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.62971737
42NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.61573598
43* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60278383
44HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.59396408
45TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54768656
46OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.54130209
47* CBX2_27304074_Chip-Seq_ESCs_Mouse1.53632396
48ZNF274_21170338_ChIP-Seq_K562_Hela1.51716267
49* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50709559
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.50513686
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.49844100
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47821764
53BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.46791364
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.46347292
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45095318
56PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43513162
57CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43449867
58FUS_26573619_Chip-Seq_HEK293_Human1.41550726
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40262142
60IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40195012
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.38561210
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.38117905
63PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.37129684
64RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.36821057
65* STAT3_23295773_ChIP-Seq_U87_Human1.36259935
66CBP_20019798_ChIP-Seq_JUKART_Human1.34965760
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.34965760
68SOX2_21211035_ChIP-Seq_LN229_Gbm1.34785396
69GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33474506
70ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31584245
71NR3C1_23031785_ChIP-Seq_PC12_Mouse1.31034438
72AR_25329375_ChIP-Seq_VCAP_Human1.30417307
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29756091
74IGF1R_20145208_ChIP-Seq_DFB_Human1.28941675
75EZH2_27294783_Chip-Seq_NPCs_Mouse1.25819417
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.24806990
77TCF4_23295773_ChIP-Seq_U87_Human1.23661811
78TP53_16413492_ChIP-PET_HCT116_Human1.22856327
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21519303
80P53_22387025_ChIP-Seq_ESCs_Mouse1.21365766
81WT1_19549856_ChIP-ChIP_CCG9911_Human1.20976273
82ER_23166858_ChIP-Seq_MCF-7_Human1.20519470
83TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20467084
84* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20390473
85MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.19681349
86* RNF2_27304074_Chip-Seq_NSC_Mouse1.19378143
87TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17728984
88AHR_22903824_ChIP-Seq_MCF-7_Human1.17390843
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17247731
90RING1B_27294783_Chip-Seq_ESCs_Mouse1.16232678
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.15741918
92VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15691186
93* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15512890
94STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15402061
95* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15402002
96LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14447340
97CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.14171515
98NANOG_18555785_Chip-Seq_ESCs_Mouse1.13270146
99RUNX2_22187159_ChIP-Seq_PCA_Human1.12830741
100AR_19668381_ChIP-Seq_PC3_Human1.12822537
101SMAD_19615063_ChIP-ChIP_OVARY_Human1.12698183
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12049132
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11971585
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11971585
105WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11936109
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11900290
107* SOX9_26525672_Chip-Seq_HEART_Mouse1.10973123
108CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10245681
109BCAT_22108803_ChIP-Seq_LS180_Human1.09679611
110TP53_18474530_ChIP-ChIP_U2OS_Human1.09444078
111YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09201903
112PRDM14_20953172_ChIP-Seq_ESCs_Human1.08745229
113FOXM1_26456572_ChIP-Seq_MCF-7_Human1.08420750
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07914222
115KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07524909
116TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07231736
117SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06752457
118PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06701036
119TCF4_22108803_ChIP-Seq_LS180_Human1.06540553
120RING1B_27294783_Chip-Seq_NPCs_Mouse1.06398141
121EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06214521
122PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05822901
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04662176
124MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02809662
125P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00859298
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.98543296
127JUN_21703547_ChIP-Seq_K562_Human0.98187928
128ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.96382889
129EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95494956
130KDM2B_26808549_Chip-Seq_REH_Human0.94690879
131E2F1_18555785_Chip-Seq_ESCs_Mouse0.94603188
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.93260912
133ERG_21242973_ChIP-ChIP_JURKAT_Human0.92731389

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.81752805
2MP0003880_abnormal_central_pattern4.45831714
3MP0003635_abnormal_synaptic_transmissio3.87492349
4MP0004270_analgesia3.79530974
5MP0006292_abnormal_olfactory_placode3.48164521
6MP0009745_abnormal_behavioral_response3.18311337
7MP0002063_abnormal_learning/memory/cond3.15735177
8MP0002064_seizures2.90410559
9MP0001968_abnormal_touch/_nociception2.74561959
10MP0002572_abnormal_emotion/affect_behav2.67053403
11MP0009046_muscle_twitch2.64347566
12MP0001486_abnormal_startle_reflex2.60551045
13MP0002272_abnormal_nervous_system2.50344162
14MP0002734_abnormal_mechanical_nocicepti2.43642343
15MP0005423_abnormal_somatic_nervous2.41511323
16MP0003121_genomic_imprinting2.33770007
17MP0003890_abnormal_embryonic-extraembry2.29988971
18MP0000778_abnormal_nervous_system2.29118558
19MP0002638_abnormal_pupillary_reflex2.25907452
20MP0002736_abnormal_nociception_after2.15537577
21MP0001440_abnormal_grooming_behavior2.12746310
22MP0009780_abnormal_chondrocyte_physiolo2.11294659
23MP0008877_abnormal_DNA_methylation2.09239896
24MP0008057_abnormal_DNA_replication2.08109210
25MP0002822_catalepsy2.07084912
26MP0001501_abnormal_sleep_pattern1.99382970
27MP0002735_abnormal_chemical_nociception1.96488223
28MP0002067_abnormal_sensory_capabilities1.88129856
29MP0002184_abnormal_innervation1.86361612
30MP0002733_abnormal_thermal_nociception1.83099460
31MP0002557_abnormal_social/conspecific_i1.76636483
32MP0004885_abnormal_endolymph1.76178119
33MP0004924_abnormal_behavior1.75193358
34MP0005386_behavior/neurological_phenoty1.75193358
35MP0008789_abnormal_olfactory_epithelium1.70107502
36MP0001970_abnormal_pain_threshold1.69337652
37MP0004811_abnormal_neuron_physiology1.65498781
38MP0001529_abnormal_vocalization1.63563688
39MP0003283_abnormal_digestive_organ1.62368053
40MP0001984_abnormal_olfaction1.61785121
41MP0005248_abnormal_Harderian_gland1.61684091
42MP0006276_abnormal_autonomic_nervous1.60836302
43MP0008569_lethality_at_weaning1.57439466
44MP0000955_abnormal_spinal_cord1.54385379
45MP0003787_abnormal_imprinting1.51543371
46MP0001188_hyperpigmentation1.50965094
47MP0002909_abnormal_adrenal_gland1.48561095
48MP0002160_abnormal_reproductive_system1.48494120
49MP0002882_abnormal_neuron_morphology1.46371111
50MP0001905_abnormal_dopamine_level1.42548465
51MP0003329_amyloid_beta_deposits1.41858396
52MP0004858_abnormal_nervous_system1.40324493
53MP0003879_abnormal_hair_cell1.40175267
54MP0002009_preneoplasia1.39567375
55MP0003123_paternal_imprinting1.38658034
56MP0002928_abnormal_bile_duct1.38499749
57MP0001293_anophthalmia1.38251092
58MP0002066_abnormal_motor_capabilities/c1.37345053
59MP0004133_heterotaxia1.37186544
60MP0002233_abnormal_nose_morphology1.33770989
61MP0005645_abnormal_hypothalamus_physiol1.32842695
62MP0005646_abnormal_pituitary_gland1.32812917
63MP0004215_abnormal_myocardial_fiber1.30654628
64MP0002938_white_spotting1.29390132
65MP0004742_abnormal_vestibular_system1.26924731
66MP0002234_abnormal_pharynx_morphology1.24758193
67MP0003633_abnormal_nervous_system1.23660459
68MP0001502_abnormal_circadian_rhythm1.23542936
69MP0003937_abnormal_limbs/digits/tail_de1.21549278
70MP0002152_abnormal_brain_morphology1.19210952
71MP0001177_atelectasis1.18292932
72MP0000920_abnormal_myelination1.17964144
73MP0000569_abnormal_digit_pigmentation1.13950890
74MP0000428_abnormal_craniofacial_morphol1.12814027
75MP0003122_maternal_imprinting1.12368380
76MP0005410_abnormal_fertilization1.12196513
77MP0005409_darkened_coat_color1.11887275
78MP0000427_abnormal_hair_cycle1.11516983
79MP0000631_abnormal_neuroendocrine_gland1.07658321
80MP0003631_nervous_system_phenotype1.05777146
81MP0003634_abnormal_glial_cell1.03714186
82MP0005551_abnormal_eye_electrophysiolog1.03301848
83MP0001299_abnormal_eye_distance/1.02544490
84MP0001963_abnormal_hearing_physiology0.99997860
85MP0004142_abnormal_muscle_tone0.99893105
86MP0003950_abnormal_plasma_membrane0.98324046
87MP0002229_neurodegeneration0.98016267
88MP0005391_vision/eye_phenotype0.97315633
89MP0000013_abnormal_adipose_tissue0.96452323
90MP0004145_abnormal_muscle_electrophysio0.95536446
91MP0001286_abnormal_eye_development0.94819866
92MP0005171_absent_coat_pigmentation0.92502930
93MP0010386_abnormal_urinary_bladder0.92486521
94MP0003567_abnormal_fetal_cardiomyocyte0.92124696
95MP0005499_abnormal_olfactory_system0.91286687
96MP0005394_taste/olfaction_phenotype0.91286687
97MP0003755_abnormal_palate_morphology0.90443644
98MP0000751_myopathy0.89999237
99MP0005195_abnormal_posterior_eye0.89607153
100MP0002092_abnormal_eye_morphology0.89031116
101MP0001485_abnormal_pinna_reflex0.88455074
102MP0002752_abnormal_somatic_nervous0.88131573
103MP0002069_abnormal_eating/drinking_beha0.86389705
104MP0003195_calcinosis0.85449058
105MP0003690_abnormal_glial_cell0.84587450
106MP0006072_abnormal_retinal_apoptosis0.83105757
107MP0005623_abnormal_meninges_morphology0.82961987
108MP0005379_endocrine/exocrine_gland_phen0.77647346
109MP0003935_abnormal_craniofacial_develop0.76466603
110MP0010030_abnormal_orbit_morphology0.75768569
111MP0002751_abnormal_autonomic_nervous0.75228182
112MP0000049_abnormal_middle_ear0.74650197
113MP0002081_perinatal_lethality0.74060505
114MP0003632_abnormal_nervous_system0.74036014
115MP0000749_muscle_degeneration0.73712938
116MP0003861_abnormal_nervous_system0.73410726
117MP0004043_abnormal_pH_regulation0.73200739
118MP0010234_abnormal_vibrissa_follicle0.72827454
119MP0002837_dystrophic_cardiac_calcinosis0.72329357
120MP0004085_abnormal_heartbeat0.72067139
121MP0002697_abnormal_eye_size0.71818250
122MP0005535_abnormal_body_temperature0.70569190
123MP0000026_abnormal_inner_ear0.68882900
124MP0008874_decreased_physiological_sensi0.67223897
125MP0004130_abnormal_muscle_cell0.65619501
126MP0002090_abnormal_vision0.65141775
127MP0005187_abnormal_penis_morphology0.65052368
128MP0001664_abnormal_digestion0.64623175
129MP0002876_abnormal_thyroid_physiology0.64043861
130MP0004134_abnormal_chest_morphology0.63968987
131MP0003698_abnormal_male_reproductive0.63181506
132MP0001943_abnormal_respiration0.62709675
133MP0002102_abnormal_ear_morphology0.60363295
134MP0008872_abnormal_physiological_respon0.56213397
135MP0005253_abnormal_eye_physiology0.53693601
136MP0008961_abnormal_basal_metabolism0.51375255
137MP0003385_abnormal_body_wall0.51225056
138MP0004484_altered_response_of0.50806527

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.78000851
2Focal seizures (HP:0007359)5.17177647
3Myokymia (HP:0002411)5.07056835
4Visual hallucinations (HP:0002367)4.52855888
5Atonic seizures (HP:0010819)4.23760798
6Epileptic encephalopathy (HP:0200134)4.23676459
7Febrile seizures (HP:0002373)3.77531055
8Absence seizures (HP:0002121)3.70940320
9Dialeptic seizures (HP:0011146)3.53481857
10Progressive cerebellar ataxia (HP:0002073)3.42458976
11Supranuclear gaze palsy (HP:0000605)3.38292276
12Action tremor (HP:0002345)3.31006667
13Hepatoblastoma (HP:0002884)3.27978518
14Dynein arm defect of respiratory motile cilia (HP:0012255)3.26475570
15Absent/shortened dynein arms (HP:0200106)3.26475570
16Generalized tonic-clonic seizures (HP:0002069)3.25285419
17Broad-based gait (HP:0002136)3.23730154
18Hyperventilation (HP:0002883)3.15030073
19Insidious onset (HP:0003587)3.02488271
20Termporal pattern (HP:0011008)3.02488271
21Abnormal pancreas size (HP:0012094)2.99466580
22Ankle clonus (HP:0011448)2.95846956
23Gaze-evoked nystagmus (HP:0000640)2.90007476
24Neurofibrillary tangles (HP:0002185)2.89762555
25Cerebral inclusion bodies (HP:0100314)2.86893959
26Truncal ataxia (HP:0002078)2.85751414
27Abnormality of the corticospinal tract (HP:0002492)2.83016780
28Amblyopia (HP:0000646)2.82140936
29Excessive salivation (HP:0003781)2.79280100
30Drooling (HP:0002307)2.79280100
31Nephronophthisis (HP:0000090)2.77498809
32Impaired vibration sensation in the lower limbs (HP:0002166)2.73648635
33Dysmetria (HP:0001310)2.69798121
34Urinary bladder sphincter dysfunction (HP:0002839)2.68917937
35Poor eye contact (HP:0000817)2.68114657
36Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.65659788
37Degeneration of the lateral corticospinal tracts (HP:0002314)2.65659788
38Absent speech (HP:0001344)2.61362903
39Papilledema (HP:0001085)2.58955710
40Spastic gait (HP:0002064)2.52813787
41Abnormality of the renal medulla (HP:0100957)2.47506907
42Pancreatic fibrosis (HP:0100732)2.47409059
43Overgrowth (HP:0001548)2.46748666
44Urinary urgency (HP:0000012)2.44501599
45True hermaphroditism (HP:0010459)2.44065435
46Calf muscle hypertrophy (HP:0008981)2.42728657
47Anxiety (HP:0000739)2.42195528
48Medial flaring of the eyebrow (HP:0010747)2.41384745
49Hemiparesis (HP:0001269)2.40909236
50Epileptiform EEG discharges (HP:0011182)2.40334696
51Depression (HP:0000716)2.40271514
52Neoplasm of the adrenal cortex (HP:0100641)2.39957998
53Volvulus (HP:0002580)2.37406020
54Dysdiadochokinesis (HP:0002075)2.36518992
55Limb dystonia (HP:0002451)2.36404467
56Impaired social interactions (HP:0000735)2.34629434
57Abnormal social behavior (HP:0012433)2.34629434
58Pancreatic cysts (HP:0001737)2.33192234
59Abnormal ciliary motility (HP:0012262)2.32639882
60Intention tremor (HP:0002080)2.30369203
61EEG with generalized epileptiform discharges (HP:0011198)2.30137276
62Poor coordination (HP:0002370)2.29750185
63Mutism (HP:0002300)2.29669921
64Genital tract atresia (HP:0001827)2.29324432
65Progressive inability to walk (HP:0002505)2.29239556
66Abnormal respiratory motile cilium physiology (HP:0012261)2.28812051
67Papillary thyroid carcinoma (HP:0002895)2.28567178
68Vaginal atresia (HP:0000148)2.27088250
69Chronic hepatic failure (HP:0100626)2.23639918
70Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.23606312
71Stereotypic behavior (HP:0000733)2.22712758
72Postural instability (HP:0002172)2.22343825
73Megalencephaly (HP:0001355)2.21242653
74Congenital primary aphakia (HP:0007707)2.21144442
75Abnormal eating behavior (HP:0100738)2.20727546
76Retinal dysplasia (HP:0007973)2.19922276
77Exotropia (HP:0000577)2.18936958
78Blue irides (HP:0000635)2.18894207
79Intestinal atresia (HP:0011100)2.18251704
80Hypsarrhythmia (HP:0002521)2.17335042
81Torticollis (HP:0000473)2.16075211
82Amyotrophic lateral sclerosis (HP:0007354)2.10345184
83Scanning speech (HP:0002168)2.10086383
84Lower limb muscle weakness (HP:0007340)2.07156010
85Abnormal respiratory motile cilium morphology (HP:0005938)2.04703644
86Abnormal respiratory epithelium morphology (HP:0012253)2.04703644
87Abnormality of the labia minora (HP:0012880)2.03283233
88Muscle hypertrophy of the lower extremities (HP:0008968)2.03226220
89Widely spaced teeth (HP:0000687)2.02250756
90Abnormality of the lower motor neuron (HP:0002366)2.02078006
91Abnormality of the antihelix (HP:0009738)2.01132904
92Focal dystonia (HP:0004373)1.99926574
93Nephrogenic diabetes insipidus (HP:0009806)1.96349729
94Abnormality of the left ventricular outflow tract (HP:0011103)1.95547873
95Subaortic stenosis (HP:0001682)1.95547873
96Molar tooth sign on MRI (HP:0002419)1.95166482
97Abnormality of midbrain morphology (HP:0002418)1.95166482
98Genetic anticipation (HP:0003743)1.94756916
99Pulmonic stenosis (HP:0001642)1.94645274
100Type II lissencephaly (HP:0007260)1.93351241
101Impaired smooth pursuit (HP:0007772)1.92843271
102Gait imbalance (HP:0002141)1.92812228
103Aplasia involving bones of the extremities (HP:0009825)1.92266345
104Aplasia involving bones of the upper limbs (HP:0009823)1.92266345
105Aplasia of the phalanges of the hand (HP:0009802)1.92266345
106Aqueductal stenosis (HP:0002410)1.91460626
107Supernumerary spleens (HP:0009799)1.90671528
108Buphthalmos (HP:0000557)1.90592804
109Optic nerve hypoplasia (HP:0000609)1.89991210
110Bradykinesia (HP:0002067)1.89971774
111Colon cancer (HP:0003003)1.88875420
112Abnormality of the renal cortex (HP:0011035)1.88609346
113Abnormality of salivation (HP:0100755)1.88424343
114Generalized myoclonic seizures (HP:0002123)1.85114388
115Impaired vibratory sensation (HP:0002495)1.84211438
116Fetal akinesia sequence (HP:0001989)1.83116233
117Thyroid carcinoma (HP:0002890)1.82549750
118Hypothermia (HP:0002045)1.82472701
119Protruding tongue (HP:0010808)1.81855055
120Lower limb asymmetry (HP:0100559)1.80464309
121Hip dysplasia (HP:0001385)1.78551914
122Ankyloglossia (HP:0010296)1.77587411
123Abnormal hair whorl (HP:0010721)1.76413411
124Hypoventilation (HP:0002791)1.75878134
125Abnormality of ocular smooth pursuit (HP:0000617)1.75398543
126Agitation (HP:0000713)1.75278245
127Craniofacial dystonia (HP:0012179)1.74916941
128Hypoplasia of the brainstem (HP:0002365)1.74714162
129Aplasia/Hypoplasia of the brainstem (HP:0007362)1.74714162
130Abnormality of the aortic arch (HP:0012303)1.74561311
131Inability to walk (HP:0002540)1.73582758
132Akinesia (HP:0002304)1.73330554
133Diplopia (HP:0000651)1.73131141
134Abnormality of binocular vision (HP:0011514)1.73131141
135Short 4th metacarpal (HP:0010044)1.73022153
136Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.73022153
137Hyperthyroidism (HP:0000836)1.72822926
138Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.72374374
139Gait ataxia (HP:0002066)1.70916562
140Exercise-induced muscle cramps (HP:0003710)1.70659963
141Pheochromocytoma (HP:0002666)1.70462667
142Aplasia/Hypoplasia of the lens (HP:0008063)1.70179402
143Specific learning disability (HP:0001328)1.69786052
144Renal cortical cysts (HP:0000803)1.69088524
145Prolonged QT interval (HP:0001657)1.68719514
146Oligodactyly (hands) (HP:0001180)1.68664163
147Aplasia/Hypoplasia of the tongue (HP:0010295)1.67807506
148Rhabdomyosarcoma (HP:0002859)1.65453707
149Cutaneous finger syndactyly (HP:0010554)1.65426943
150Neoplasm of the oral cavity (HP:0100649)1.65363187
151Postaxial hand polydactyly (HP:0001162)1.63713488
152Occipital encephalocele (HP:0002085)1.63578730
153Abnormality of the metopic suture (HP:0005556)1.62821527
154Abnormal sex determination (HP:0012244)1.61678414
155Sex reversal (HP:0012245)1.61678414
156Biliary tract neoplasm (HP:0100574)1.61610320
157Abnormal biliary tract morphology (HP:0012440)1.59250172
158Truncal obesity (HP:0001956)1.59195042
159Narrow forehead (HP:0000341)1.57851447
160Abnormality of the fovea (HP:0000493)1.57035326
161Tubulointerstitial nephritis (HP:0001970)1.54658580
162Small hand (HP:0200055)1.54446555

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.94942313
2EPHA43.88083800
3MARK13.63164825
4MAP3K43.30336201
5MAP2K72.67365614
6MAP3K92.57150718
7MINK12.32626563
8PNCK2.19670509
9NTRK22.19466143
10TNIK2.16167170
11AKT32.04687943
12CASK2.03585641
13MKNK21.98078716
14DAPK21.85254990
15RIPK41.83600335
16MAP2K41.81230552
17MAPK131.79611026
18STK38L1.75532474
19PAK61.70241064
20NTRK11.69198380
21PRKD31.68716074
22TRIM281.62182128
23BMPR1B1.57646652
24MAP4K21.54295409
25SIK21.53205737
26PLK21.48454176
27LATS11.47106857
28STK391.46400737
29MAP3K121.46399049
30STK31.44668540
31CDK51.43638575
32MAP3K21.37981985
33KSR11.37749720
34BRD41.37585537
35KSR21.37487597
36BRSK21.34056845
37DYRK31.30657712
38TYRO31.28271417
39UHMK11.22549905
40MKNK11.20411252
41CAMKK11.19555914
42FES1.18528204
43GRK51.13173915
44WNK41.11744693
45PRKCG1.08827310
46OXSR11.08465298
47SGK4941.07791120
48SGK2231.07791120
49DAPK11.07677052
50NEK11.05001009
51BMPR21.04509284
52ARAF1.01069134
53CAMK2A1.01050633
54CSNK1G21.00329319
55ICK1.00063250
56MAP3K130.99290861
57ACVR1B0.99242727
58FGFR20.97152790
59WNK30.96639850
60PTK2B0.95799568
61CAMK1G0.95199480
62NUAK10.94307751
63PRPF4B0.93892420
64SGK20.91728656
65CAMK2B0.91266418
66CAMK1D0.88924509
67CAMKK20.87870279
68WNK10.86997597
69STK110.83537311
70RET0.83430253
71PLK30.83076762
72NLK0.82470337
73PHKG10.82013295
74PHKG20.82013295
75ERBB30.79915323
76PAK30.78120339
77STK380.77108360
78SGK10.76873638
79DYRK1A0.76559200
80GRK10.74911570
81CDK190.74436872
82CDK140.73476306
83CDK180.70613160
84PKN10.70183663
85CDK150.68870226
86BCR0.66948499
87CAMK10.66596476
88NME10.66548127
89MAP3K60.66154237
90FGR0.65934229
91FRK0.64807045
92DMPK0.64097638
93WEE10.62720617
94PRKCE0.62131096
95LATS20.62042028
96SGK30.61696502
97CAMK40.61228257
98* MARK20.60893006
99PIK3CA0.60107717
100PRKCH0.59513276
101DDR20.57785118
102CSNK1A1L0.56887264
103CDK11A0.56291506
104PDK10.56213001
105PDPK10.55968977
106TAF10.55380502
107PRKCZ0.55313372
108FER0.54997789
109DYRK20.53819290
110STK240.53327565
111RAF10.52687566
112FYN0.52545359
113CSNK1G30.51985568
114CSNK1D0.51866143
115CAMK2D0.50439475
116PDK30.48521186
117PDK40.48521186
118INSRR0.47799162
119MAPKAPK50.46030537
120MAPK100.44433290
121PRKG10.44426497
122RPS6KA20.43524201
123RPS6KA30.43501137
124MAP3K70.40926923
125CSNK1E0.39991427
126GRK70.39557093
127PINK10.39460681
128RPS6KB10.39009329
129FGFR10.38842498
130CSNK1G10.38823009
131MAP3K50.38456587
132OBSCN0.38312103
133PASK0.38089063
134PRKAA10.37830172
135ATM0.36433050
136CDK30.36287474

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.37385009
2Long-term potentiation_Homo sapiens_hsa047202.67062902
3Circadian entrainment_Homo sapiens_hsa047132.61038125
4Glutamatergic synapse_Homo sapiens_hsa047242.58688401
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57976938
6Olfactory transduction_Homo sapiens_hsa047402.52515583
7GABAergic synapse_Homo sapiens_hsa047272.46759565
8Synaptic vesicle cycle_Homo sapiens_hsa047212.45944772
9Amphetamine addiction_Homo sapiens_hsa050312.43447779
10Morphine addiction_Homo sapiens_hsa050322.42313787
11Dopaminergic synapse_Homo sapiens_hsa047282.15749974
12Salivary secretion_Homo sapiens_hsa049701.98441980
13Renin secretion_Homo sapiens_hsa049241.93283948
14Cholinergic synapse_Homo sapiens_hsa047251.91134048
15Insulin secretion_Homo sapiens_hsa049111.90112945
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.81723558
17Gastric acid secretion_Homo sapiens_hsa049711.80917406
18Serotonergic synapse_Homo sapiens_hsa047261.80375889
19Protein export_Homo sapiens_hsa030601.76015180
20Cocaine addiction_Homo sapiens_hsa050301.73519341
21Long-term depression_Homo sapiens_hsa047301.71958626
22Taste transduction_Homo sapiens_hsa047421.71296177
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.68155888
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66589581
25Oxytocin signaling pathway_Homo sapiens_hsa049211.56822096
26Axon guidance_Homo sapiens_hsa043601.48373439
27Calcium signaling pathway_Homo sapiens_hsa040201.48352207
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.47826519
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46375690
30GnRH signaling pathway_Homo sapiens_hsa049121.34492140
31Basal cell carcinoma_Homo sapiens_hsa052171.31457409
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.31023629
33Gap junction_Homo sapiens_hsa045401.29782918
34cAMP signaling pathway_Homo sapiens_hsa040241.28620976
35Hippo signaling pathway_Homo sapiens_hsa043901.28231393
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.25139267
37Type II diabetes mellitus_Homo sapiens_hsa049301.24508538
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24439791
39Regulation of autophagy_Homo sapiens_hsa041401.22794399
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.22536430
41Collecting duct acid secretion_Homo sapiens_hsa049661.21857833
42Estrogen signaling pathway_Homo sapiens_hsa049151.15207319
43Phototransduction_Homo sapiens_hsa047441.14652717
44TGF-beta signaling pathway_Homo sapiens_hsa043501.14505216
45Glioma_Homo sapiens_hsa052141.13581443
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13446906
47RNA degradation_Homo sapiens_hsa030181.09890823
48Non-homologous end-joining_Homo sapiens_hsa034501.09680544
49Melanogenesis_Homo sapiens_hsa049161.08860329
50Dorso-ventral axis formation_Homo sapiens_hsa043201.08575332
51ErbB signaling pathway_Homo sapiens_hsa040121.08494126
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08130049
53cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06844252
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.97378590
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.94006296
56Propanoate metabolism_Homo sapiens_hsa006400.91894358
57Selenocompound metabolism_Homo sapiens_hsa004500.89986528
58FoxO signaling pathway_Homo sapiens_hsa040680.87807493
59Vibrio cholerae infection_Homo sapiens_hsa051100.82232709
60Cardiac muscle contraction_Homo sapiens_hsa042600.82174333
61Choline metabolism in cancer_Homo sapiens_hsa052310.82089688
62Lysine degradation_Homo sapiens_hsa003100.81993831
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.81904443
64Thyroid hormone synthesis_Homo sapiens_hsa049180.79806553
65Pancreatic secretion_Homo sapiens_hsa049720.79020626
66Melanoma_Homo sapiens_hsa052180.77461440
67MAPK signaling pathway_Homo sapiens_hsa040100.75251857
68Oocyte meiosis_Homo sapiens_hsa041140.74685189
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74252764
70Ras signaling pathway_Homo sapiens_hsa040140.73478046
71Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72395714
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72263871
73Glucagon signaling pathway_Homo sapiens_hsa049220.71000594
74Fanconi anemia pathway_Homo sapiens_hsa034600.68619998
75Dilated cardiomyopathy_Homo sapiens_hsa054140.67302985
76Adherens junction_Homo sapiens_hsa045200.66418976
77Wnt signaling pathway_Homo sapiens_hsa043100.66087061
78Alcoholism_Homo sapiens_hsa050340.65426016
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64870082
80Basal transcription factors_Homo sapiens_hsa030220.64329243
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62987256
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.62196409
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62013445
84VEGF signaling pathway_Homo sapiens_hsa043700.61792655
85Alzheimers disease_Homo sapiens_hsa050100.60463195
86Renal cell carcinoma_Homo sapiens_hsa052110.55513926
87Rap1 signaling pathway_Homo sapiens_hsa040150.55269707
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54814599
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.54312470
90Tight junction_Homo sapiens_hsa045300.54139905
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54094057
92mTOR signaling pathway_Homo sapiens_hsa041500.53302260
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53054615
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.51740323
95Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51560201
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48675124
97Protein digestion and absorption_Homo sapiens_hsa049740.48379023
98Endometrial cancer_Homo sapiens_hsa052130.48126387
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47508423
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.47241195
101Pathways in cancer_Homo sapiens_hsa052000.47127733
102African trypanosomiasis_Homo sapiens_hsa051430.46696403
103Vitamin B6 metabolism_Homo sapiens_hsa007500.46263495
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46212403
105Ovarian steroidogenesis_Homo sapiens_hsa049130.45728604
106Inositol phosphate metabolism_Homo sapiens_hsa005620.44869988
107Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44850653
108Prion diseases_Homo sapiens_hsa050200.43130718
109Ether lipid metabolism_Homo sapiens_hsa005650.42823365
110Circadian rhythm_Homo sapiens_hsa047100.42577926
111Type I diabetes mellitus_Homo sapiens_hsa049400.40599564
112Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40406377
113Insulin signaling pathway_Homo sapiens_hsa049100.40357596
114Hedgehog signaling pathway_Homo sapiens_hsa043400.39858660
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38760375
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38592159
117* Endocytosis_Homo sapiens_hsa041440.38108190
118Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37883096
119Colorectal cancer_Homo sapiens_hsa052100.36111924
120Non-small cell lung cancer_Homo sapiens_hsa052230.35729844
121Fatty acid biosynthesis_Homo sapiens_hsa000610.33350247
122Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32216021
123Butanoate metabolism_Homo sapiens_hsa006500.31498411
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30747872
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30279366

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