Rank | Gene Set | Z-score |
---|---|---|
1 | locomotory exploration behavior (GO:0035641) | 4.50356229 |
2 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.28329700 |
3 | vocalization behavior (GO:0071625) | 4.08715963 |
4 | synaptic vesicle maturation (GO:0016188) | 3.97945644 |
5 | semaphorin-plexin signaling pathway (GO:0071526) | 3.96084764 |
6 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.93768433 |
7 | cellular potassium ion homeostasis (GO:0030007) | 3.89483917 |
8 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.88650974 |
9 | phosphate ion transport (GO:0006817) | 3.87709356 |
10 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.86404683 |
11 | protein carboxylation (GO:0018214) | 3.80127679 |
12 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.80127679 |
13 | sodium ion export (GO:0071436) | 3.77958092 |
14 | drug transmembrane transport (GO:0006855) | 3.72503509 |
15 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.65707432 |
16 | aminoglycoside antibiotic metabolic process (GO:0030647) | 3.59118158 |
17 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.57982163 |
18 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.55782967 |
19 | glutamate secretion (GO:0014047) | 3.47802192 |
20 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.45011187 |
21 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.39082536 |
22 | cell-cell junction maintenance (GO:0045217) | 3.34880720 |
23 | regulation of synapse structural plasticity (GO:0051823) | 3.30993832 |
24 | synaptic vesicle exocytosis (GO:0016079) | 3.30794758 |
25 | layer formation in cerebral cortex (GO:0021819) | 3.28502121 |
26 | exploration behavior (GO:0035640) | 3.26630363 |
27 | urate metabolic process (GO:0046415) | 3.25433409 |
28 | phosphate ion transmembrane transport (GO:0035435) | 3.24727496 |
29 | cell communication by electrical coupling (GO:0010644) | 3.23285628 |
30 | organic cation transport (GO:0015695) | 3.23184559 |
31 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.22693119 |
32 | negative regulation of catenin import into nucleus (GO:0035414) | 3.21101015 |
33 | adenosine receptor signaling pathway (GO:0001973) | 3.20787805 |
34 | neurotransmitter secretion (GO:0007269) | 3.20417485 |
35 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.16743641 |
36 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.15943203 |
37 | regulation of skeletal muscle contraction (GO:0014819) | 3.14224118 |
38 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.13595610 |
39 | protein retention in ER lumen (GO:0006621) | 3.13355530 |
40 | dendritic spine morphogenesis (GO:0060997) | 3.11505815 |
41 | neuronal action potential propagation (GO:0019227) | 3.11058634 |
42 | cerebellar granule cell differentiation (GO:0021707) | 3.10174867 |
43 | quaternary ammonium group transport (GO:0015697) | 3.10110521 |
44 | lysine metabolic process (GO:0006553) | 3.09927380 |
45 | lysine catabolic process (GO:0006554) | 3.09927380 |
46 | mannose metabolic process (GO:0006013) | 3.02289666 |
47 | protein localization to synapse (GO:0035418) | 3.00911396 |
48 | regulation of synapse maturation (GO:0090128) | 3.00894330 |
49 | potassium ion import (GO:0010107) | 3.00327640 |
50 | postsynaptic membrane organization (GO:0001941) | 2.97991198 |
51 | regulation of synaptic vesicle transport (GO:1902803) | 2.97798478 |
52 | drug transport (GO:0015893) | 2.95968879 |
53 | synaptic transmission, glutamatergic (GO:0035249) | 2.95073193 |
54 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.94471740 |
55 | gamma-aminobutyric acid transport (GO:0015812) | 2.92313231 |
56 | positive regulation of membrane potential (GO:0045838) | 2.91919799 |
57 | synaptic vesicle endocytosis (GO:0048488) | 2.91623122 |
58 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.91378807 |
59 | dendrite morphogenesis (GO:0048813) | 2.90756761 |
60 | exogenous drug catabolic process (GO:0042738) | 2.89538281 |
61 | metanephric tubule development (GO:0072170) | 2.88404526 |
62 | metanephric nephron tubule development (GO:0072234) | 2.88404526 |
63 | proline transport (GO:0015824) | 2.88035412 |
64 | glutamate receptor signaling pathway (GO:0007215) | 2.87891008 |
65 | neuron cell-cell adhesion (GO:0007158) | 2.86032172 |
66 | negative regulation of fatty acid transport (GO:2000192) | 2.82982336 |
67 | drug catabolic process (GO:0042737) | 2.82080791 |
68 | cellular response to ATP (GO:0071318) | 2.81859464 |
69 | GDP-mannose metabolic process (GO:0019673) | 2.81521631 |
70 | neurotransmitter transport (GO:0006836) | 2.77948408 |
71 | positive regulation of synapse maturation (GO:0090129) | 2.77379196 |
72 | adherens junction assembly (GO:0034333) | 2.77156711 |
73 | neuromuscular process controlling balance (GO:0050885) | 2.76385699 |
74 | regulation of ARF protein signal transduction (GO:0032012) | 2.75106207 |
75 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.75059264 |
76 | cellular sodium ion homeostasis (GO:0006883) | 2.73376644 |
77 | positive regulation of protein kinase C signaling (GO:0090037) | 2.72812720 |
78 | glycine transport (GO:0015816) | 2.70886172 |
79 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.70743522 |
80 | metanephric nephron epithelium development (GO:0072243) | 2.69716018 |
81 | adenine nucleotide transport (GO:0051503) | 2.69602905 |
82 | neuron recognition (GO:0008038) | 2.69193057 |
83 | regulation of ARF GTPase activity (GO:0032312) | 2.68278321 |
84 | neuron-neuron synaptic transmission (GO:0007270) | 2.67018676 |
85 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.66940037 |
86 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.65926673 |
87 | focal adhesion assembly (GO:0048041) | 2.65789006 |
88 | cell-substrate adherens junction assembly (GO:0007045) | 2.65789006 |
89 | basement membrane organization (GO:0071711) | 2.64435447 |
90 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.64205815 |
91 | cell junction maintenance (GO:0034331) | 2.63212117 |
92 | long-term memory (GO:0007616) | 2.62450411 |
93 | amino-acid betaine transport (GO:0015838) | 2.60874566 |
94 | carnitine transport (GO:0015879) | 2.60874566 |
95 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.57784683 |
96 | auditory behavior (GO:0031223) | 2.57526869 |
97 | convergent extension (GO:0060026) | 2.57313815 |
98 | central nervous system myelination (GO:0022010) | 2.56751255 |
99 | axon ensheathment in central nervous system (GO:0032291) | 2.56751255 |
100 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.56267387 |
101 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.55543339 |
102 | L-amino acid import (GO:0043092) | 2.55430104 |
103 | endothelial cell chemotaxis (GO:0035767) | 2.54758707 |
104 | plasma membrane repair (GO:0001778) | 2.53636686 |
105 | potassium ion homeostasis (GO:0055075) | 2.53533687 |
106 | regulation of postsynaptic membrane potential (GO:0060078) | 2.52777946 |
107 | urinary tract smooth muscle contraction (GO:0014848) | 2.52568835 |
108 | establishment of nucleus localization (GO:0040023) | 2.50732962 |
109 | membrane repolarization (GO:0086009) | 2.50654430 |
110 | cell communication involved in cardiac conduction (GO:0086065) | 2.50587933 |
111 | activation of protein kinase A activity (GO:0034199) | 2.50377687 |
112 | response to parathyroid hormone (GO:0071107) | 2.50369525 |
113 | metanephric epithelium development (GO:0072207) | 2.46692567 |
114 | axonal fasciculation (GO:0007413) | 2.46084740 |
115 | aspartate family amino acid catabolic process (GO:0009068) | 2.45983379 |
116 | regulation of synaptic plasticity (GO:0048167) | 2.45716800 |
117 | dopamine receptor signaling pathway (GO:0007212) | 2.45693727 |
118 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.45356914 |
119 | membrane repolarization during action potential (GO:0086011) | 2.44847661 |
120 | dendritic spine organization (GO:0097061) | 2.44500582 |
121 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.43736654 |
122 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.42387398 |
123 | regulation of neurotransmitter levels (GO:0001505) | 2.42368152 |
124 | membrane depolarization during action potential (GO:0086010) | 2.41515786 |
125 | regulation of dendritic spine development (GO:0060998) | 2.40744535 |
126 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.40374894 |
127 | membrane hyperpolarization (GO:0060081) | 2.40021033 |
128 | proline biosynthetic process (GO:0006561) | 2.40015962 |
129 | response to mercury ion (GO:0046689) | 2.39989853 |
130 | sensory perception of taste (GO:0050909) | 2.38608746 |
131 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.37463469 |
132 | regulation of early endosome to late endosome transport (GO:2000641) | 2.36615789 |
133 | tricarboxylic acid metabolic process (GO:0072350) | 2.36080417 |
134 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.35528108 |
135 | neuronal ion channel clustering (GO:0045161) | 2.34777633 |
136 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.33648735 |
137 | camera-type eye morphogenesis (GO:0048593) | 2.33451797 |
138 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.33223851 |
139 | positive regulation of axonogenesis (GO:0050772) | 2.32999711 |
140 | cellular response to ammonium ion (GO:0071242) | 2.32585369 |
141 | neuromuscular synaptic transmission (GO:0007274) | 2.32537922 |
142 | cell migration in hindbrain (GO:0021535) | 2.32492169 |
143 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.32086830 |
144 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.30879493 |
145 | atrioventricular valve morphogenesis (GO:0003181) | 2.30311170 |
146 | neuromuscular junction development (GO:0007528) | 2.29938074 |
147 | amino acid import (GO:0043090) | 2.29924483 |
148 | negative regulation of cell size (GO:0045792) | 2.29676609 |
149 | purine nucleotide transport (GO:0015865) | 2.28983236 |
150 | lung epithelium development (GO:0060428) | 2.28424875 |
151 | positive regulation of dendrite development (GO:1900006) | 2.26694469 |
152 | regulation of cholesterol metabolic process (GO:0090181) | 2.25604358 |
153 | protein targeting to plasma membrane (GO:0072661) | 2.20710203 |
154 | positive regulation of dendritic spine development (GO:0060999) | 2.19978663 |
155 | proline metabolic process (GO:0006560) | 2.19411102 |
156 | actin filament bundle assembly (GO:0051017) | 2.19285249 |
157 | actin filament bundle organization (GO:0061572) | 2.19285249 |
158 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.17452712 |
159 | regulation of cholesterol homeostasis (GO:2000188) | 2.15919263 |
160 | regulation of establishment of planar polarity (GO:0090175) | 2.15005453 |
161 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.13219093 |
162 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.12826841 |
163 | axon extension (GO:0048675) | 2.11060537 |
164 | cochlea morphogenesis (GO:0090103) | 2.09913827 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.08042289 |
2 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.69489905 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.60959461 |
4 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.59248507 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.57108956 |
6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.56255158 |
7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.50326434 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.49873247 |
9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.49873247 |
10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.38170868 |
11 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.34910762 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.31114411 |
13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.30354453 |
14 | RACK7_27058665_Chip-Seq_MCF-7_Human | 2.28959808 |
15 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.28851981 |
16 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.25189065 |
17 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.23050219 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.22132131 |
19 | * P68_20966046_ChIP-Seq_HELA_Human | 2.18477760 |
20 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.16566811 |
21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.09085330 |
22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.09036009 |
23 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.07914958 |
24 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.07855452 |
25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.06704463 |
26 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.06321339 |
27 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.04592870 |
28 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.04428374 |
29 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.00610223 |
30 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.94785587 |
31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.90246885 |
32 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.89587818 |
33 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89174074 |
34 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.85642719 |
35 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.84252367 |
36 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.79647267 |
37 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.78801931 |
38 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.76449684 |
39 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.72650778 |
40 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.69289695 |
41 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.68289218 |
42 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.67407662 |
43 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.67132078 |
44 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.66955695 |
45 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.63673378 |
46 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.63240183 |
47 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.57469654 |
48 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.54671506 |
49 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.51694882 |
50 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.51624726 |
51 | MYC_22102868_ChIP-Seq_BL_Human | 1.51078619 |
52 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.49966769 |
53 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.48608410 |
54 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.47717650 |
55 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.44812797 |
56 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.42761160 |
57 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.41884921 |
58 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.41451098 |
59 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.40471872 |
60 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.40357749 |
61 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.39592100 |
62 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.37256942 |
63 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.33691150 |
64 | KDM2B_26808549_Chip-Seq_K562_Human | 1.32932914 |
65 | * RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.32317661 |
66 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.30845337 |
67 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.30842801 |
68 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.28114735 |
69 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.27058368 |
70 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.26118728 |
71 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.24503789 |
72 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.24147752 |
73 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.23901063 |
74 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.23898903 |
75 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.23777906 |
76 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.23325986 |
77 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.23278567 |
78 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.23028464 |
79 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.22832022 |
80 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.22638042 |
81 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.22190062 |
82 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.21585384 |
83 | * RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.20317807 |
84 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.19629244 |
85 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19587797 |
86 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.19585796 |
87 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.19070768 |
88 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.18972629 |
89 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.18708827 |
90 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.17909285 |
91 | MAF_26560356_Chip-Seq_TH2_Human | 1.17891004 |
92 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.17687248 |
93 | * AR_19668381_ChIP-Seq_PC3_Human | 1.15057033 |
94 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.14966315 |
95 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.14962779 |
96 | * PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.14680118 |
97 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.14562586 |
98 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.14362922 |
99 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.14339000 |
100 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.14016607 |
101 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.13633121 |
102 | * PHF8_20622854_ChIP-Seq_HELA_Human | 1.13562045 |
103 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.13397852 |
104 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.12945849 |
105 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.12215192 |
106 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.11951371 |
107 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.11153055 |
108 | SA1_27219007_Chip-Seq_Bcells_Human | 1.10618091 |
109 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.10458802 |
110 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.10050598 |
111 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.09782647 |
112 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.09754178 |
113 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.09423563 |
114 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.09086828 |
115 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.08627476 |
116 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 1.08183408 |
117 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.07910284 |
118 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.07868227 |
119 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.05749500 |
120 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.04451876 |
121 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.03783991 |
122 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.03633414 |
123 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.03428220 |
124 | RXR_22108803_ChIP-Seq_LS180_Human | 1.00787607 |
125 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.99782221 |
126 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98813873 |
127 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.98196674 |
128 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97481911 |
129 | STAT3_23295773_ChIP-Seq_U87_Human | 0.97377056 |
130 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.96675305 |
131 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.95330695 |
132 | AR_25329375_ChIP-Seq_VCAP_Human | 0.94815078 |
133 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.94516803 |
134 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.93422744 |
135 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.93011342 |
136 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.91837569 |
137 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.91706776 |
138 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.91700769 |
139 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.91528232 |
140 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.91243383 |
141 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.87159922 |
142 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86961897 |
143 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.86576631 |
144 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.85811617 |
145 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.85409980 |
146 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.85051460 |
147 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84256047 |
148 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.84129030 |
149 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.83944599 |
150 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.83942973 |
151 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.83587254 |
152 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.83212943 |
153 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.83179829 |
154 | * ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.83073789 |
155 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.82315058 |
156 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.81682572 |
157 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.81115717 |
158 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.80769935 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.41387956 |
2 | MP0003705_abnormal_hypodermis_morpholog | 3.84180339 |
3 | MP0005409_darkened_coat_color | 3.56501006 |
4 | MP0004043_abnormal_pH_regulation | 3.36355955 |
5 | MP0005171_absent_coat_pigmentation | 3.21060196 |
6 | MP0003635_abnormal_synaptic_transmissio | 3.14546635 |
7 | MP0004270_analgesia | 3.06035501 |
8 | MP0003880_abnormal_central_pattern | 2.81592479 |
9 | MP0002063_abnormal_learning/memory/cond | 2.50083956 |
10 | MP0009745_abnormal_behavioral_response | 2.47956484 |
11 | MP0005360_urolithiasis | 2.41071577 |
12 | MP0000751_myopathy | 2.35605886 |
13 | MP0002064_seizures | 2.35483866 |
14 | MP0004885_abnormal_endolymph | 2.34311113 |
15 | MP0009046_muscle_twitch | 2.33319085 |
16 | MP0003136_yellow_coat_color | 2.17594636 |
17 | MP0002249_abnormal_larynx_morphology | 2.13460564 |
18 | MP0001986_abnormal_taste_sensitivity | 2.10154721 |
19 | MP0003123_paternal_imprinting | 2.06544167 |
20 | MP0009780_abnormal_chondrocyte_physiolo | 2.04202112 |
21 | MP0002822_catalepsy | 2.02521077 |
22 | MP0004858_abnormal_nervous_system | 2.01529370 |
23 | MP0001348_abnormal_lacrimal_gland | 1.96553485 |
24 | MP0002572_abnormal_emotion/affect_behav | 1.95200499 |
25 | MP0001765_abnormal_ion_homeostasis | 1.94013346 |
26 | MP0001486_abnormal_startle_reflex | 1.92761675 |
27 | MP0004145_abnormal_muscle_electrophysio | 1.91374060 |
28 | MP0005257_abnormal_intraocular_pressure | 1.88451613 |
29 | MP0001188_hyperpigmentation | 1.82442535 |
30 | MP0005423_abnormal_somatic_nervous | 1.77713540 |
31 | MP0002272_abnormal_nervous_system | 1.75326067 |
32 | MP0008961_abnormal_basal_metabolism | 1.74279660 |
33 | MP0005174_abnormal_tail_pigmentation | 1.73137719 |
34 | MP0001968_abnormal_touch/_nociception | 1.72187790 |
35 | MP0002734_abnormal_mechanical_nocicepti | 1.71025123 |
36 | MP0005076_abnormal_cell_differentiation | 1.69780683 |
37 | MP0001440_abnormal_grooming_behavior | 1.68448640 |
38 | MP0005332_abnormal_amino_acid | 1.64238961 |
39 | MP0005377_hearing/vestibular/ear_phenot | 1.64113467 |
40 | MP0003878_abnormal_ear_physiology | 1.64113467 |
41 | MP0004019_abnormal_vitamin_homeostasis | 1.63153703 |
42 | MP0003879_abnormal_hair_cell | 1.63147902 |
43 | MP0003646_muscle_fatigue | 1.61875561 |
44 | MP0003283_abnormal_digestive_organ | 1.61176303 |
45 | MP0000778_abnormal_nervous_system | 1.58431205 |
46 | MP0002067_abnormal_sensory_capabilities | 1.54180908 |
47 | MP0002735_abnormal_chemical_nociception | 1.51624907 |
48 | MP0003329_amyloid_beta_deposits | 1.50328814 |
49 | MP0000003_abnormal_adipose_tissue | 1.46971001 |
50 | MP0008438_abnormal_cutaneous_collagen | 1.46346123 |
51 | MP0003279_aneurysm | 1.44870674 |
52 | MP0003195_calcinosis | 1.44314907 |
53 | MP0000569_abnormal_digit_pigmentation | 1.42601574 |
54 | MP0009384_cardiac_valve_regurgitation | 1.40617798 |
55 | MP0008569_lethality_at_weaning | 1.39128973 |
56 | MP0001958_emphysema | 1.35679954 |
57 | MP0000747_muscle_weakness | 1.32600887 |
58 | MP0000678_abnormal_parathyroid_gland | 1.32267488 |
59 | MP0001849_ear_inflammation | 1.30556309 |
60 | MP0001501_abnormal_sleep_pattern | 1.28089020 |
61 | MP0000750_abnormal_muscle_regeneration | 1.26595886 |
62 | MP0002736_abnormal_nociception_after | 1.26093337 |
63 | MP0000013_abnormal_adipose_tissue | 1.25969948 |
64 | MP0002909_abnormal_adrenal_gland | 1.25459990 |
65 | MP0004811_abnormal_neuron_physiology | 1.24884368 |
66 | MP0002837_dystrophic_cardiac_calcinosis | 1.24697793 |
67 | MP0002557_abnormal_social/conspecific_i | 1.21726272 |
68 | MP0000566_synostosis | 1.19813692 |
69 | MP0002066_abnormal_motor_capabilities/c | 1.18655178 |
70 | MP0003633_abnormal_nervous_system | 1.18653861 |
71 | MP0004924_abnormal_behavior | 1.13370913 |
72 | MP0005386_behavior/neurological_phenoty | 1.13370913 |
73 | MP0002733_abnormal_thermal_nociception | 1.12289300 |
74 | MP0002184_abnormal_innervation | 1.11696032 |
75 | MP0003122_maternal_imprinting | 1.11450222 |
76 | MP0003091_abnormal_cell_migration | 1.10441872 |
77 | MP0001177_atelectasis | 1.10048129 |
78 | MP0004215_abnormal_myocardial_fiber | 1.09097686 |
79 | MP0001756_abnormal_urination | 1.08359975 |
80 | MP0004484_altered_response_of | 1.07328340 |
81 | MP0004742_abnormal_vestibular_system | 1.07318943 |
82 | MP0003942_abnormal_urinary_system | 1.06888253 |
83 | MP0001970_abnormal_pain_threshold | 1.06436793 |
84 | MP0000955_abnormal_spinal_cord | 1.06394603 |
85 | MP0002089_abnormal_postnatal_growth/wei | 1.06133518 |
86 | MP0005535_abnormal_body_temperature | 1.06087193 |
87 | MP0005330_cardiomyopathy | 1.05473452 |
88 | MP0010030_abnormal_orbit_morphology | 1.04142322 |
89 | MP0004233_abnormal_muscle_weight | 1.03585049 |
90 | MP0005167_abnormal_blood-brain_barrier | 1.02875168 |
91 | MP0005058_abnormal_lysosome_morphology | 1.02102170 |
92 | MP0003453_abnormal_keratinocyte_physiol | 1.01143885 |
93 | MP0002882_abnormal_neuron_morphology | 1.00621172 |
94 | MP0009643_abnormal_urine_homeostasis | 0.99808277 |
95 | MP0005620_abnormal_muscle_contractility | 0.99433168 |
96 | MP0000538_abnormal_urinary_bladder | 0.98974186 |
97 | MP0003172_abnormal_lysosome_physiology | 0.97312659 |
98 | MP0004130_abnormal_muscle_cell | 0.96494917 |
99 | MP0001346_abnormal_lacrimal_gland | 0.96368993 |
100 | MP0000749_muscle_degeneration | 0.95888499 |
101 | MP0001485_abnormal_pinna_reflex | 0.95377666 |
102 | MP0005623_abnormal_meninges_morphology | 0.95265688 |
103 | MP0002138_abnormal_hepatobiliary_system | 0.94402648 |
104 | MP0004036_abnormal_muscle_relaxation | 0.94178733 |
105 | MP0002234_abnormal_pharynx_morphology | 0.93769917 |
106 | MP0004272_abnormal_basement_membrane | 0.93403342 |
107 | MP0001661_extended_life_span | 0.92232266 |
108 | MP0003631_nervous_system_phenotype | 0.92192864 |
109 | MP0000759_abnormal_skeletal_muscle | 0.92075296 |
110 | MP0002069_abnormal_eating/drinking_beha | 0.91819466 |
111 | MP0005375_adipose_tissue_phenotype | 0.90960400 |
112 | MP0003634_abnormal_glial_cell | 0.89827416 |
113 | MP0000534_abnormal_ureter_morphology | 0.89582699 |
114 | MP0003137_abnormal_impulse_conducting | 0.89258228 |
115 | MP0010386_abnormal_urinary_bladder | 0.87771061 |
116 | MP0002139_abnormal_hepatobiliary_system | 0.87579294 |
117 | MP0005636_abnormal_mineral_homeostasis | 0.86485284 |
118 | MP0004085_abnormal_heartbeat | 0.86387613 |
119 | MP0002152_abnormal_brain_morphology | 0.84999665 |
120 | MP0004087_abnormal_muscle_fiber | 0.84446432 |
121 | MP0004185_abnormal_adipocyte_glucose | 0.83178809 |
122 | MP0003075_altered_response_to | 0.83108746 |
123 | MP0001502_abnormal_circadian_rhythm | 0.82221039 |
124 | MP0005503_abnormal_tendon_morphology | 0.82195694 |
125 | MP0005083_abnormal_biliary_tract | 0.80295591 |
126 | MP0002136_abnormal_kidney_physiology | 0.79699514 |
127 | MP0001963_abnormal_hearing_physiology | 0.79325797 |
128 | MP0010368_abnormal_lymphatic_system | 0.79320448 |
129 | MP0000733_abnormal_muscle_development | 0.78569090 |
130 | MP0008874_decreased_physiological_sensi | 0.76580681 |
131 | MP0003690_abnormal_glial_cell | 0.76357007 |
132 | MP0000767_abnormal_smooth_muscle | 0.76118114 |
133 | MP0005646_abnormal_pituitary_gland | 0.75698021 |
134 | MP0002896_abnormal_bone_mineralization | 0.75585312 |
135 | MP0003385_abnormal_body_wall | 0.75302600 |
136 | MP0009840_abnormal_foam_cell | 0.74892670 |
137 | MP0002269_muscular_atrophy | 0.74586129 |
138 | MP0003115_abnormal_respiratory_system | 0.74581534 |
139 | MP0005369_muscle_phenotype | 0.74438756 |
140 | MP0002160_abnormal_reproductive_system | 0.74412397 |
141 | MP0002106_abnormal_muscle_physiology | 0.73896404 |
142 | MP0005666_abnormal_adipose_tissue | 0.72400917 |
143 | MP0010630_abnormal_cardiac_muscle | 0.72244555 |
144 | MP0002108_abnormal_muscle_morphology | 0.71785201 |
145 | MP0001664_abnormal_digestion | 0.71742365 |
146 | MP0000920_abnormal_myelination | 0.71549277 |
147 | MP0002229_neurodegeneration | 0.70830550 |
148 | MP0000230_abnormal_systemic_arterial | 0.70238763 |
149 | MP0002932_abnormal_joint_morphology | 0.70163542 |
150 | MP0002638_abnormal_pupillary_reflex | 0.69782607 |
151 | MP0001299_abnormal_eye_distance/ | 0.68889720 |
152 | MP0002116_abnormal_craniofacial_bone | 0.65647681 |
153 | MP0000462_abnormal_digestive_system | 0.64639083 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased circulating renin level (HP:0000848) | 5.81592181 |
2 | Metabolic alkalosis (HP:0200114) | 4.98750476 |
3 | Ulnar bowing (HP:0003031) | 4.74345739 |
4 | Gout (HP:0001997) | 4.67474452 |
5 | Turricephaly (HP:0000262) | 4.66831625 |
6 | Hypokalemic alkalosis (HP:0001949) | 4.61185566 |
7 | Hyperactive renin-angiotensin system (HP:0000841) | 4.38493197 |
8 | Focal motor seizures (HP:0011153) | 4.22612252 |
9 | Polyuria (HP:0000103) | 4.20762668 |
10 | Hypomagnesemia (HP:0002917) | 4.19963503 |
11 | Annular pancreas (HP:0001734) | 4.16086762 |
12 | Thin bony cortex (HP:0002753) | 4.14538271 |
13 | Abnormal urine output (HP:0012590) | 4.01208710 |
14 | Myokymia (HP:0002411) | 4.00556985 |
15 | Abnormality of chloride homeostasis (HP:0011422) | 3.83552995 |
16 | Abnormality of renal excretion (HP:0011036) | 3.81318374 |
17 | Polydipsia (HP:0001959) | 3.76558967 |
18 | Abnormal drinking behavior (HP:0030082) | 3.76558967 |
19 | Akinesia (HP:0002304) | 3.67284645 |
20 | Testicular atrophy (HP:0000029) | 3.60353976 |
21 | Protrusio acetabuli (HP:0003179) | 3.52903205 |
22 | Coronal craniosynostosis (HP:0004440) | 3.51745296 |
23 | Abnormality of magnesium homeostasis (HP:0004921) | 3.51296184 |
24 | Rib fusion (HP:0000902) | 3.46551907 |
25 | Abnormality of renin-angiotensin system (HP:0000847) | 3.29229724 |
26 | Focal seizures (HP:0007359) | 3.23227979 |
27 | Hemorrhage of the eye (HP:0011885) | 3.21615911 |
28 | Hyperaldosteronism (HP:0000859) | 3.17416195 |
29 | Hyperuricemia (HP:0002149) | 3.13011899 |
30 | Increased purine levels (HP:0004368) | 3.13011899 |
31 | Hypercalciuria (HP:0002150) | 3.01047589 |
32 | Thin ribs (HP:0000883) | 2.96210231 |
33 | Shallow orbits (HP:0000586) | 2.88909896 |
34 | Tetany (HP:0001281) | 2.85528272 |
35 | Visual hallucinations (HP:0002367) | 2.83372264 |
36 | Hyperacusis (HP:0010780) | 2.80194929 |
37 | Myopathic facies (HP:0002058) | 2.79176932 |
38 | Cerebral aneurysm (HP:0004944) | 2.78209973 |
39 | Hyperventilation (HP:0002883) | 2.74111472 |
40 | Renal salt wasting (HP:0000127) | 2.72108880 |
41 | Intestinal fistula (HP:0100819) | 2.70169591 |
42 | Hypokalemia (HP:0002900) | 2.66019542 |
43 | Bowing of the arm (HP:0006488) | 2.64678790 |
44 | Bowed forearm bones (HP:0003956) | 2.64678790 |
45 | Mesangial abnormality (HP:0001966) | 2.62363231 |
46 | Alkalosis (HP:0001948) | 2.62229991 |
47 | Action tremor (HP:0002345) | 2.60178632 |
48 | Vaginal fistula (HP:0004320) | 2.58415887 |
49 | Abnormality of potassium homeostasis (HP:0011042) | 2.58192554 |
50 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.56752785 |
51 | Exercise-induced myalgia (HP:0003738) | 2.56092504 |
52 | Proximal tubulopathy (HP:0000114) | 2.52265764 |
53 | Abnormal eating behavior (HP:0100738) | 2.51864133 |
54 | Popliteal pterygium (HP:0009756) | 2.50344080 |
55 | Abnormal social behavior (HP:0012433) | 2.47071316 |
56 | Impaired social interactions (HP:0000735) | 2.47071316 |
57 | Broad-based gait (HP:0002136) | 2.45085393 |
58 | Atrioventricular block (HP:0001678) | 2.42628630 |
59 | Postural instability (HP:0002172) | 2.39209184 |
60 | Ketoacidosis (HP:0001993) | 2.38604368 |
61 | Poor eye contact (HP:0000817) | 2.37559746 |
62 | Choanal stenosis (HP:0000452) | 2.37325254 |
63 | Joint hemorrhage (HP:0005261) | 2.36422870 |
64 | Rectal fistula (HP:0100590) | 2.34677357 |
65 | Rectovaginal fistula (HP:0000143) | 2.34677357 |
66 | Broad metatarsal (HP:0001783) | 2.33118165 |
67 | Ankle clonus (HP:0011448) | 2.32783198 |
68 | Myotonia (HP:0002486) | 2.30271152 |
69 | Progressive cerebellar ataxia (HP:0002073) | 2.29140506 |
70 | Dysmetric saccades (HP:0000641) | 2.28771799 |
71 | Epileptic encephalopathy (HP:0200134) | 2.28401500 |
72 | Abnormality of purine metabolism (HP:0004352) | 2.27778652 |
73 | Abnormality of the lower motor neuron (HP:0002366) | 2.27523695 |
74 | Facial hemangioma (HP:0000329) | 2.26537379 |
75 | Aplasia of the musculature (HP:0100854) | 2.25574763 |
76 | Bronchomalacia (HP:0002780) | 2.24599979 |
77 | Generalized tonic-clonic seizures (HP:0002069) | 2.24235817 |
78 | Hyperglycinuria (HP:0003108) | 2.22223017 |
79 | Arterial tortuosity (HP:0005116) | 2.19920765 |
80 | Joint stiffness (HP:0001387) | 2.19281883 |
81 | Supranuclear gaze palsy (HP:0000605) | 2.16491300 |
82 | Vascular tortuosity (HP:0004948) | 2.15391106 |
83 | Bladder diverticulum (HP:0000015) | 2.14133338 |
84 | Abnormality of the intrinsic pathway (HP:0010989) | 2.12048958 |
85 | Mask-like facies (HP:0000298) | 2.11994853 |
86 | Cervical subluxation (HP:0003308) | 2.11878569 |
87 | Fetal akinesia sequence (HP:0001989) | 2.11604334 |
88 | Dysdiadochokinesis (HP:0002075) | 2.11566671 |
89 | Febrile seizures (HP:0002373) | 2.11461632 |
90 | Urinary urgency (HP:0000012) | 2.10686275 |
91 | Lymphangioma (HP:0100764) | 2.10185177 |
92 | Mitral regurgitation (HP:0001653) | 2.08316529 |
93 | Atonic seizures (HP:0010819) | 2.07691686 |
94 | Insomnia (HP:0100785) | 2.07681423 |
95 | Hyperkalemia (HP:0002153) | 2.06756295 |
96 | Pointed chin (HP:0000307) | 2.06159879 |
97 | Poikiloderma (HP:0001029) | 2.05798292 |
98 | Premature rupture of membranes (HP:0001788) | 2.04292158 |
99 | Absence seizures (HP:0002121) | 2.04175123 |
100 | Anxiety (HP:0000739) | 2.01761310 |
101 | Exercise-induced muscle cramps (HP:0003710) | 2.01610787 |
102 | Anteriorly placed anus (HP:0001545) | 2.01605524 |
103 | Narrow nasal bridge (HP:0000446) | 2.01412664 |
104 | Bundle branch block (HP:0011710) | 1.99973001 |
105 | Confusion (HP:0001289) | 1.99727225 |
106 | Adrenal overactivity (HP:0002717) | 1.98684217 |
107 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.98315792 |
108 | Pterygium (HP:0001059) | 1.98177607 |
109 | Ventricular fibrillation (HP:0001663) | 1.98150310 |
110 | Depression (HP:0000716) | 1.97846040 |
111 | Abnormal atrioventricular conduction (HP:0005150) | 1.97783146 |
112 | Genu recurvatum (HP:0002816) | 1.97600573 |
113 | Hip contracture (HP:0003273) | 1.97405269 |
114 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.97396664 |
115 | Neonatal onset (HP:0003623) | 1.96647284 |
116 | Gaze-evoked nystagmus (HP:0000640) | 1.96070620 |
117 | Neurofibrillary tangles (HP:0002185) | 1.95953280 |
118 | Nephrocalcinosis (HP:0000121) | 1.95324037 |
119 | Muscle fiber splitting (HP:0003555) | 1.94436936 |
120 | Difficulty running (HP:0009046) | 1.93882242 |
121 | Stridor (HP:0010307) | 1.91765440 |
122 | Heart block (HP:0012722) | 1.91745392 |
123 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.91224305 |
124 | Elfin facies (HP:0004428) | 1.90417614 |
125 | Prolonged partial thromboplastin time (HP:0003645) | 1.90024074 |
126 | Abnormality of the calf musculature (HP:0001430) | 1.87755297 |
127 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.87692412 |
128 | Broad face (HP:0000283) | 1.86317954 |
129 | Obstructive sleep apnea (HP:0002870) | 1.86289615 |
130 | Abnormality of the aortic arch (HP:0012303) | 1.86009015 |
131 | Calf muscle hypertrophy (HP:0008981) | 1.85034135 |
132 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.84794407 |
133 | Dysmetria (HP:0001310) | 1.84237494 |
134 | Renal tubular acidosis (HP:0001947) | 1.83691369 |
135 | Rectal prolapse (HP:0002035) | 1.83387757 |
136 | Abnormality of proline metabolism (HP:0010907) | 1.83227366 |
137 | Hydroxyprolinuria (HP:0003080) | 1.83227366 |
138 | Hypoventilation (HP:0002791) | 1.82759817 |
139 | Intention tremor (HP:0002080) | 1.82516419 |
140 | Neonatal short-limb short stature (HP:0008921) | 1.81531353 |
141 | Sudden death (HP:0001699) | 1.81365353 |
142 | Dialeptic seizures (HP:0011146) | 1.80077621 |
143 | Increased variability in muscle fiber diameter (HP:0003557) | 1.77877448 |
144 | Supernumerary nipples (HP:0002558) | 1.76780914 |
145 | Abnormality of glycine metabolism (HP:0010895) | 1.76669642 |
146 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.76669642 |
147 | Genetic anticipation (HP:0003743) | 1.76580153 |
148 | Nephrolithiasis (HP:0000787) | 1.76071726 |
149 | Ketosis (HP:0001946) | 1.75233143 |
150 | Upper limb amyotrophy (HP:0009129) | 1.74916555 |
151 | Distal upper limb amyotrophy (HP:0007149) | 1.74916555 |
152 | Hemiplegia (HP:0002301) | 1.74887229 |
153 | Deep venous thrombosis (HP:0002625) | 1.74565123 |
154 | Biconcave vertebral bodies (HP:0004586) | 1.74556319 |
155 | Renal duplication (HP:0000075) | 1.73174101 |
156 | Vertebral clefting (HP:0008428) | 1.72712348 |
157 | Congenital hip dislocation (HP:0001374) | 1.72332105 |
158 | Prolonged QT interval (HP:0001657) | 1.72077388 |
159 | Status epilepticus (HP:0002133) | 1.71551138 |
160 | Disproportionate tall stature (HP:0001519) | 1.71068796 |
161 | Atelectasis (HP:0100750) | 1.70868760 |
162 | Germ cell neoplasia (HP:0100728) | 1.70766667 |
163 | Easy fatigability (HP:0003388) | 1.70168779 |
164 | Aortic aneurysm (HP:0004942) | 1.67972534 |
165 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.67794486 |
166 | Aplasia of the phalanges of the hand (HP:0009802) | 1.67794486 |
167 | Aplasia involving bones of the extremities (HP:0009825) | 1.67794486 |
168 | Spina bifida occulta (HP:0003298) | 1.67715400 |
169 | Scanning speech (HP:0002168) | 1.66971005 |
170 | Tibial bowing (HP:0002982) | 1.66404388 |
171 | Hand muscle atrophy (HP:0009130) | 1.65663319 |
172 | Long palpebral fissure (HP:0000637) | 1.64648293 |
173 | Lower limb asymmetry (HP:0100559) | 1.64530807 |
174 | Dislocated radial head (HP:0003083) | 1.64341663 |
175 | Delayed epiphyseal ossification (HP:0002663) | 1.63840352 |
176 | Cerebral inclusion bodies (HP:0100314) | 1.62023131 |
177 | Widely patent fontanelles and sutures (HP:0004492) | 1.61569874 |
178 | Polyphagia (HP:0002591) | 1.61371607 |
179 | Type 1 muscle fiber predominance (HP:0003803) | 1.61236581 |
180 | Asymmetry of the thorax (HP:0001555) | 1.60096804 |
181 | Rapidly progressive (HP:0003678) | 1.60007775 |
182 | Achilles tendon contracture (HP:0001771) | 1.59992126 |
183 | Partial duplication of thumb phalanx (HP:0009944) | 1.59159037 |
184 | Round ear (HP:0100830) | 1.58665711 |
185 | Ulnar deviation of the wrist (HP:0003049) | 1.58524949 |
186 | Bowel diverticulosis (HP:0005222) | 1.57977534 |
187 | Abnormality of the radial head (HP:0003995) | 1.57775251 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK4 | 3.92020255 |
2 | EPHA4 | 3.52048647 |
3 | MAPK15 | 3.45389883 |
4 | NTRK3 | 3.38080590 |
5 | WNK3 | 3.37145772 |
6 | OXSR1 | 3.37004011 |
7 | SIK1 | 2.60830130 |
8 | EEF2K | 2.36400831 |
9 | MAP3K4 | 2.25363887 |
10 | MARK1 | 2.20421085 |
11 | MAP3K9 | 2.17671838 |
12 | DAPK2 | 2.15403140 |
13 | PRKD3 | 2.06580281 |
14 | STK38 | 2.05876690 |
15 | STK39 | 1.99300674 |
16 | PAK6 | 1.87079058 |
17 | MINK1 | 1.82746592 |
18 | FGFR4 | 1.75418587 |
19 | ERN1 | 1.74032136 |
20 | SMG1 | 1.73694788 |
21 | PKN2 | 1.72350689 |
22 | WNK1 | 1.66188500 |
23 | MAP2K4 | 1.64579402 |
24 | PINK1 | 1.53898657 |
25 | NTRK1 | 1.50665197 |
26 | SGK223 | 1.49116003 |
27 | SGK494 | 1.49116003 |
28 | CDK12 | 1.48175691 |
29 | PHKG2 | 1.47612548 |
30 | PHKG1 | 1.47612548 |
31 | KSR2 | 1.44088422 |
32 | TYRO3 | 1.42638143 |
33 | CAMKK1 | 1.39567111 |
34 | NTRK2 | 1.38011478 |
35 | RPS6KA2 | 1.33890816 |
36 | MAP3K7 | 1.23459596 |
37 | RIPK1 | 1.21832615 |
38 | ARAF | 1.21668082 |
39 | DDR2 | 1.21643188 |
40 | RIPK4 | 1.20244928 |
41 | CDK5 | 1.13272183 |
42 | SGK3 | 1.11132282 |
43 | MAP2K7 | 1.10730887 |
44 | TRIB3 | 1.10522753 |
45 | MTOR | 1.10331549 |
46 | KSR1 | 1.08037587 |
47 | SIK2 | 1.07925130 |
48 | SGK2 | 1.04597133 |
49 | PTK2B | 1.02871352 |
50 | PDK4 | 1.02643065 |
51 | PDK3 | 1.02643065 |
52 | LATS2 | 1.02453773 |
53 | TAOK1 | 1.00004530 |
54 | PAK3 | 0.96857618 |
55 | STK11 | 0.96691352 |
56 | PRKCH | 0.95276996 |
57 | DYRK1B | 0.94935906 |
58 | NEK1 | 0.94398993 |
59 | DAPK1 | 0.93261992 |
60 | SGK1 | 0.93121588 |
61 | DMPK | 0.92797525 |
62 | EPHB2 | 0.90013362 |
63 | ICK | 0.89190384 |
64 | PRPF4B | 0.88813132 |
65 | MARK2 | 0.88092219 |
66 | CDK11A | 0.87752012 |
67 | MAP3K10 | 0.86056413 |
68 | CAMK1G | 0.85781914 |
69 | MAP3K12 | 0.85230700 |
70 | MAP3K2 | 0.83729642 |
71 | LMTK2 | 0.83429919 |
72 | PRKCG | 0.82126886 |
73 | TTN | 0.79109325 |
74 | PNCK | 0.78910915 |
75 | PDGFRA | 0.78798387 |
76 | RPS6KL1 | 0.78128600 |
77 | RPS6KC1 | 0.78128600 |
78 | OBSCN | 0.75493526 |
79 | MAP2K3 | 0.74730543 |
80 | TNIK | 0.71245332 |
81 | GRK5 | 0.69235931 |
82 | UHMK1 | 0.67064460 |
83 | BMX | 0.66921831 |
84 | BRAF | 0.66328243 |
85 | FGFR2 | 0.66195965 |
86 | PDK2 | 0.64296427 |
87 | PTK2 | 0.64077386 |
88 | RPS6KA6 | 0.63519388 |
89 | CAMK1 | 0.63494446 |
90 | CAMK2A | 0.63478409 |
91 | CDK14 | 0.62493668 |
92 | FER | 0.61918978 |
93 | RET | 0.61351082 |
94 | PLK2 | 0.60552143 |
95 | PRKD2 | 0.60102453 |
96 | PRKD1 | 0.58727040 |
97 | CAMK4 | 0.58049492 |
98 | CAMK1D | 0.57971994 |
99 | STK38L | 0.57498704 |
100 | HIPK2 | 0.56797837 |
101 | MAP3K11 | 0.56581186 |
102 | CDC42BPA | 0.56281921 |
103 | MAPK13 | 0.55760796 |
104 | PDPK1 | 0.54929887 |
105 | NEK6 | 0.54881338 |
106 | MAP2K2 | 0.53278854 |
107 | MAPK11 | 0.53058324 |
108 | PRKAA1 | 0.51875133 |
109 | FGFR3 | 0.51567506 |
110 | MAPK10 | 0.50911013 |
111 | MUSK | 0.50603137 |
112 | ROCK1 | 0.50530187 |
113 | CAMKK2 | 0.50067027 |
114 | MAPK8 | 0.49742260 |
115 | RPS6KA3 | 0.49313739 |
116 | PRKCZ | 0.49179100 |
117 | PDK1 | 0.48717265 |
118 | CAMK2B | 0.47669146 |
119 | NME1 | 0.47564995 |
120 | MAP3K1 | 0.46966766 |
121 | ALK | 0.46951979 |
122 | FES | 0.46554891 |
123 | PDGFRB | 0.44844774 |
124 | INSRR | 0.43900780 |
125 | PTK6 | 0.43328183 |
126 | EPHA2 | 0.43176901 |
127 | IRAK2 | 0.42763406 |
128 | ERBB2 | 0.42466601 |
129 | MAPK12 | 0.39839931 |
130 | MAP2K1 | 0.39048392 |
131 | DAPK3 | 0.38530363 |
132 | PAK2 | 0.38051375 |
133 | CAMK2G | 0.37477531 |
134 | MAP3K13 | 0.37148610 |
135 | AKT2 | 0.36824025 |
136 | CDK15 | 0.36362355 |
137 | ROCK2 | 0.36059501 |
138 | CASK | 0.35886166 |
139 | CDK18 | 0.35620913 |
140 | FYN | 0.33662626 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.71567191 |
2 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.56740647 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.25121269 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.20619027 |
5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.16425248 |
6 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.88951109 |
7 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.81811504 |
8 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.76849406 |
9 | Circadian entrainment_Homo sapiens_hsa04713 | 1.75654141 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.74737198 |
11 | Long-term potentiation_Homo sapiens_hsa04720 | 1.73648031 |
12 | GABAergic synapse_Homo sapiens_hsa04727 | 1.73294568 |
13 | Olfactory transduction_Homo sapiens_hsa04740 | 1.67275328 |
14 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.64953899 |
15 | Salivary secretion_Homo sapiens_hsa04970 | 1.62935213 |
16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62181398 |
17 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.58627261 |
18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.56648908 |
19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.56485936 |
20 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.54806546 |
21 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.50984881 |
22 | Morphine addiction_Homo sapiens_hsa05032 | 1.48468879 |
23 | Insulin secretion_Homo sapiens_hsa04911 | 1.47942302 |
24 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.47383799 |
25 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.46072589 |
26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.45659698 |
27 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.42500836 |
28 | Bile secretion_Homo sapiens_hsa04976 | 1.38251248 |
29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.33028258 |
30 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.31026029 |
31 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.28827064 |
32 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.27989069 |
33 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.24468073 |
34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.23206812 |
35 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.22632647 |
36 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.22317751 |
37 | Renin secretion_Homo sapiens_hsa04924 | 1.21206770 |
38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.18437157 |
39 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.17514449 |
40 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.16546381 |
41 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.15364482 |
42 | Taste transduction_Homo sapiens_hsa04742 | 1.13720486 |
43 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.11188328 |
44 | Prion diseases_Homo sapiens_hsa05020 | 1.10493671 |
45 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.08329531 |
46 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.06811582 |
47 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.05111518 |
48 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.04569201 |
49 | Long-term depression_Homo sapiens_hsa04730 | 1.04130057 |
50 | Cocaine addiction_Homo sapiens_hsa05030 | 1.02759396 |
51 | Other glycan degradation_Homo sapiens_hsa00511 | 1.01989993 |
52 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.01348897 |
53 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.00858946 |
54 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.00847606 |
55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.00829109 |
56 | Mineral absorption_Homo sapiens_hsa04978 | 1.00754122 |
57 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.98824639 |
58 | Focal adhesion_Homo sapiens_hsa04510 | 0.98272196 |
59 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.96474260 |
60 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.95616211 |
61 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.95466222 |
62 | Axon guidance_Homo sapiens_hsa04360 | 0.93089786 |
63 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.92953987 |
64 | Gap junction_Homo sapiens_hsa04540 | 0.92904120 |
65 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.91253642 |
66 | Glioma_Homo sapiens_hsa05214 | 0.89453825 |
67 | Bladder cancer_Homo sapiens_hsa05219 | 0.89427883 |
68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.89005554 |
69 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.88499340 |
70 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.88180001 |
71 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.87595784 |
72 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.87514181 |
73 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.87023700 |
74 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.86828347 |
75 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.85759201 |
76 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.84013331 |
77 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.83217674 |
78 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.82868950 |
79 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.78496543 |
80 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.78303464 |
81 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.77869135 |
82 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.76173114 |
83 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.75456416 |
84 | Melanogenesis_Homo sapiens_hsa04916 | 0.74315039 |
85 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.74208563 |
86 | Lysine degradation_Homo sapiens_hsa00310 | 0.73566594 |
87 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.73164408 |
88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.72125746 |
89 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.71773804 |
90 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71763806 |
91 | Insulin resistance_Homo sapiens_hsa04931 | 0.71620528 |
92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.70839612 |
93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70510835 |
94 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.70285247 |
95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.69359740 |
96 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.68675534 |
97 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.67819895 |
98 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.66345941 |
99 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.66211062 |
100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.63580210 |
101 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.63024129 |
102 | Circadian rhythm_Homo sapiens_hsa04710 | 0.62309848 |
103 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.62065423 |
104 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.61913781 |
105 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.60811026 |
106 | * Endocytosis_Homo sapiens_hsa04144 | 0.60611516 |
107 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.60549466 |
108 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.59364549 |
109 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.59277787 |
110 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.58507971 |
111 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.57253362 |
112 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.54833870 |
113 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.54210104 |
114 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.53991040 |
115 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.51617923 |
116 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51614075 |
117 | Histidine metabolism_Homo sapiens_hsa00340 | 0.51037629 |
118 | Tight junction_Homo sapiens_hsa04530 | 0.50101103 |
119 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.50058572 |
120 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.49325482 |
121 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49221527 |
122 | Endometrial cancer_Homo sapiens_hsa05213 | 0.49106104 |
123 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47082047 |
124 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.45895515 |
125 | Peroxisome_Homo sapiens_hsa04146 | 0.45060728 |
126 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.44809541 |
127 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44552975 |
128 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.43642550 |
129 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.43126042 |
130 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43025730 |
131 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.42326727 |
132 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42069834 |
133 | Carbon metabolism_Homo sapiens_hsa01200 | 0.40990431 |