RAB20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glycosphingolipid catabolic process (GO:0046479)4.78305247
2oligosaccharide catabolic process (GO:0009313)4.46374748
3glycolipid catabolic process (GO:0019377)4.35662025
4response to peptidoglycan (GO:0032494)4.12540984
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.03925919
6cellular response to thyroid hormone stimulus (GO:0097067)3.92496993
7vitamin transmembrane transport (GO:0035461)3.90255506
8positive regulation by symbiont of host defense response (GO:0052509)3.82250985
9modulation by symbiont of host defense response (GO:0052031)3.82250985
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.82250985
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.82250985
12positive regulation by organism of defense response of other organism involved in symbiotic interact3.82250985
13modulation by symbiont of host immune response (GO:0052553)3.82250985
14folic acid transport (GO:0015884)3.76391409
15ceramide catabolic process (GO:0046514)3.71504378
16purine nucleobase biosynthetic process (GO:0009113)3.69995980
17positive regulation of chemokine biosynthetic process (GO:0045080)3.66249659
18immunoglobulin mediated immune response (GO:0016064)3.65127793
19neutrophil activation involved in immune response (GO:0002283)3.57377612
20regulation of RIG-I signaling pathway (GO:0039535)3.57018307
21lipopolysaccharide-mediated signaling pathway (GO:0031663)3.55432064
22T-helper 1 type immune response (GO:0042088)3.54286070
23hydrogen peroxide biosynthetic process (GO:0050665)3.51677443
24positive regulation of interferon-beta production (GO:0032728)3.49188735
25low-density lipoprotein particle clearance (GO:0034383)3.48823186
26regulation of T-helper 1 cell differentiation (GO:0045625)3.45468270
27folic acid metabolic process (GO:0046655)3.41707315
28response to thyroid hormone (GO:0097066)3.36151779
29positive regulation of interferon-alpha production (GO:0032727)3.35991837
30detection of external biotic stimulus (GO:0098581)3.35846763
31detection of other organism (GO:0098543)3.35703873
32positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.27420404
33negative regulation of lipid storage (GO:0010888)3.26613202
34positive regulation of cellular amide metabolic process (GO:0034250)3.22072518
35regulation of interferon-alpha production (GO:0032647)3.20308847
36ribosome assembly (GO:0042255)3.20090353
37membrane lipid catabolic process (GO:0046466)3.20024777
38regulation of chemokine biosynthetic process (GO:0045073)3.18195097
39sphingolipid catabolic process (GO:0030149)3.14409449
40superoxide anion generation (GO:0042554)3.13435409
41regulation of mast cell degranulation (GO:0043304)3.12634661
42regulation of podosome assembly (GO:0071801)3.10643791
43mitotic metaphase plate congression (GO:0007080)3.07947258
44natural killer cell mediated cytotoxicity (GO:0042267)3.05759920
45natural killer cell mediated immunity (GO:0002228)3.05759920
46macrophage activation involved in immune response (GO:0002281)3.05009779
47detection of bacterium (GO:0016045)3.04873921
48antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.04238414
49antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.04238414
50cellular extravasation (GO:0045123)3.03091338
51N-acetylneuraminate metabolic process (GO:0006054)3.02909333
52antigen processing and presentation of endogenous antigen (GO:0019883)3.02662593
53respiratory burst (GO:0045730)3.02515516
54production of molecular mediator involved in inflammatory response (GO:0002532)3.01687813
55reactive oxygen species biosynthetic process (GO:1903409)3.01468472
56skeletal muscle tissue regeneration (GO:0043403)3.01168040
57regulation of superoxide anion generation (GO:0032928)3.01057192
58positive regulation of gamma-delta T cell activation (GO:0046645)3.00351213
59regulation of macrophage chemotaxis (GO:0010758)2.99794890
60detection of biotic stimulus (GO:0009595)2.99493823
61positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.98010245
62positive regulation of leukocyte degranulation (GO:0043302)2.96694888
63regulation of interferon-beta production (GO:0032648)2.96617346
64regulation of leukocyte degranulation (GO:0043300)2.93885641
65positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.93294760
66pinocytosis (GO:0006907)2.90092739
67negative regulation of interleukin-12 production (GO:0032695)2.89835358
68interferon-gamma-mediated signaling pathway (GO:0060333)2.88082534
69amyloid precursor protein catabolic process (GO:0042987)2.88014290
70amino sugar catabolic process (GO:0046348)2.87915470
71intestinal epithelial cell development (GO:0060576)2.86281446
72macrophage activation (GO:0042116)2.85263094
73regulation of membrane protein ectodomain proteolysis (GO:0051043)2.83131081
74positive regulation of antigen processing and presentation (GO:0002579)2.82179738
75regulation of mononuclear cell migration (GO:0071675)2.81949322
76peptide catabolic process (GO:0043171)2.81925295
77regulation of myeloid leukocyte mediated immunity (GO:0002886)2.81388701
78regulation of vitamin metabolic process (GO:0030656)2.80761077
79nucleobase biosynthetic process (GO:0046112)2.80265383
80regulation of mast cell activation involved in immune response (GO:0033006)2.79497294
81positive regulation of monocyte chemotaxis (GO:0090026)2.79356656
82regulation of response to interferon-gamma (GO:0060330)2.79225095
83cellular response to arsenic-containing substance (GO:0071243)2.79115213
84protein localization to endosome (GO:0036010)2.77482912
85NIK/NF-kappaB signaling (GO:0038061)2.76612141
86germinal center formation (GO:0002467)2.76341776
87positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.75999366
88positive regulation of cholesterol efflux (GO:0010875)2.75916296
89negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.72303587
90barbed-end actin filament capping (GO:0051016)2.72137430
91granulocyte activation (GO:0036230)2.70728372
92positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.70659597
93regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.70467990
94leukocyte mediated cytotoxicity (GO:0001909)2.69103409
95interferon-gamma secretion (GO:0072643)2.68859331
96regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.68587008
97myeloid dendritic cell activation (GO:0001773)2.68561942
98monocyte chemotaxis (GO:0002548)2.68377425
99positive regulation of heat generation (GO:0031652)2.67387489
100eosinophil chemotaxis (GO:0048245)2.67050560
101regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.66965421
102response to muramyl dipeptide (GO:0032495)2.66849311
103modified amino acid transport (GO:0072337)2.66025204
104regulation of fever generation (GO:0031620)2.65630029
105negative regulation of erythrocyte differentiation (GO:0045647)2.64906371
106type I interferon signaling pathway (GO:0060337)2.64413773
107cellular response to type I interferon (GO:0071357)2.64413773
108positive regulation of Cdc42 GTPase activity (GO:0043089)2.63932567
109positive regulation of mast cell degranulation (GO:0043306)2.63360681
110positive regulation of mast cell activation involved in immune response (GO:0033008)2.63360681
111response to host immune response (GO:0052572)2.63272066
112response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.63272066
113cellular response to lipopolysaccharide (GO:0071222)2.61602924
114negative regulation of cytokine production involved in immune response (GO:0002719)2.60861075
115response to type I interferon (GO:0034340)2.59879256
116plasma lipoprotein particle clearance (GO:0034381)2.59523488
117regulation of interferon-beta biosynthetic process (GO:0045357)2.59501986
118transcription elongation from RNA polymerase III promoter (GO:0006385)2.59469448
119termination of RNA polymerase III transcription (GO:0006386)2.59469448
120B cell mediated immunity (GO:0019724)2.59092283
121regulation of cytokine secretion involved in immune response (GO:0002739)2.58670560
122regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.58377848
123positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.58066113
124regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.58047320
125response to interferon-gamma (GO:0034341)2.55490528
126regulation of type I interferon-mediated signaling pathway (GO:0060338)2.55102290
127cellular response to molecule of bacterial origin (GO:0071219)2.54972247
128negative regulation of nitric oxide biosynthetic process (GO:0045019)2.54337206
129regulation of T-helper 2 cell differentiation (GO:0045628)2.54329444
130antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.53235024
131response to protozoan (GO:0001562)2.52712318
132epithelial cell differentiation involved in prostate gland development (GO:0060742)2.52534331
133cellular response to virus (GO:0098586)2.51547493
134negative regulation by host of viral transcription (GO:0043922)2.51198887
135regulation of spindle organization (GO:0090224)2.50752710
136positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.50122277
137adhesion of symbiont to host (GO:0044406)2.49776885
138positive regulation of mast cell activation (GO:0033005)2.48976911
139negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.48184981
140negative regulation of cell killing (GO:0031342)2.48184981
141regulation of dendritic cell antigen processing and presentation (GO:0002604)2.47116267
142cytokine secretion (GO:0050663)2.47095713
143positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.44630970
144regulation of cholesterol storage (GO:0010885)2.43073502
145regulation of antigen processing and presentation (GO:0002577)2.40846971
146vitamin transport (GO:0051180)2.39246197
147DNA deamination (GO:0045006)2.38525960
148negative regulation of myeloid cell apoptotic process (GO:0033033)2.37695988
149S-adenosylmethionine metabolic process (GO:0046500)2.37079917
150regulation of vitamin D biosynthetic process (GO:0060556)2.36654972
151detection of molecule of bacterial origin (GO:0032490)2.35985708
152positive regulation of T cell apoptotic process (GO:0070234)2.35470604
153pantothenate metabolic process (GO:0015939)2.34432313
154antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.33659652
155regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.32069955
156neutrophil activation (GO:0042119)2.31589198
157urate metabolic process (GO:0046415)2.30958829
158ribosome biogenesis (GO:0042254)2.30855822
159response to xenobiotic stimulus (GO:0009410)2.30324292
160myeloid dendritic cell differentiation (GO:0043011)2.29778355
161positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.29343476
162positive regulation of chemokine production (GO:0032722)2.29184485

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse4.34863833
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.05382622
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.18490149
4BP1_19119308_ChIP-ChIP_Hs578T_Human2.63782154
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.52972012
6VDR_21846776_ChIP-Seq_THP-1_Human2.47699742
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.46387838
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.44062729
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38865649
10* IRF8_27001747_Chip-Seq_BMDM_Mouse2.36540357
11STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.31727229
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.26171141
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.23290864
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.22811777
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.19125931
16NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.15331088
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.09900690
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.06325150
19LXR_22292898_ChIP-Seq_THP-1_Human2.02759007
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.97637160
21ESR2_21235772_ChIP-Seq_MCF-7_Human1.93599830
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.90787482
23Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.90458841
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.88060902
25ZNF263_19887448_ChIP-Seq_K562_Human1.87824488
26FOXM1_23109430_ChIP-Seq_U2OS_Human1.86535571
27MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.84242959
28* SPI1_23547873_ChIP-Seq_NB4_Human1.80170223
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.78776518
30E2F7_22180533_ChIP-Seq_HELA_Human1.75727934
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.74434620
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.68735410
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.67943776
34TP63_17297297_ChIP-ChIP_HaCaT_Human1.66169975
35* SPI1_23127762_ChIP-Seq_K562_Human1.64992715
36* FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.64456246
37* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62804629
38EST1_17652178_ChIP-ChIP_JURKAT_Human1.62025553
39VDR_23849224_ChIP-Seq_CD4+_Human1.60214371
40ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.58404269
41* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.57208109
42TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.56495140
43MYC_18555785_ChIP-Seq_MESCs_Mouse1.56326369
44RACK7_27058665_Chip-Seq_MCF-7_Human1.55598738
45* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.50342984
46MYC_22102868_ChIP-Seq_BL_Human1.50318232
47CLOCK_20551151_ChIP-Seq_293T_Human1.48583888
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47251071
49* TCF7_22412390_ChIP-Seq_EML_Mouse1.46516210
50* VDR_24787735_ChIP-Seq_THP-1_Human1.46403005
51CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.45352835
52E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.44910809
53* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43413498
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.42615367
55MYC_18358816_ChIP-ChIP_MESCs_Mouse1.41512914
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.41185639
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40755844
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39074552
59KAP1_22055183_ChIP-Seq_ESCs_Mouse1.38320466
60ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36987176
61PPARA_22158963_ChIP-Seq_LIVER_Mouse1.36713943
62NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.36177178
63* LXR_22158963_ChIP-Seq_LIVER_Mouse1.35867712
64TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.35706255
65AR_21909140_ChIP-Seq_LNCAP_Human1.33847495
66SCL_19346495_ChIP-Seq_HPC-7_Human1.33752110
67BRD4_27068464_Chip-Seq_AML-cells_Mouse1.33273617
68ESR1_21235772_ChIP-Seq_MCF-7_Human1.31806670
69* RXR_22158963_ChIP-Seq_LIVER_Mouse1.31069160
70* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27564037
71MYC_19030024_ChIP-ChIP_MESCs_Mouse1.27440046
72PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.25493101
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.24941134
74VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.24275070
75NELFA_20434984_ChIP-Seq_ESCs_Mouse1.24004254
76KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23482268
77MYC_19079543_ChIP-ChIP_MESCs_Mouse1.23420576
78STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.22885579
79STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.22859277
80KDM2B_26808549_Chip-Seq_DND41_Human1.22583236
81TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.22482406
82DCP1A_22483619_ChIP-Seq_HELA_Human1.21194120
83GATA1_22383799_ChIP-Seq_G1ME_Mouse1.20762962
84SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19714748
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19504429
86MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.18774878
87TFEB_21752829_ChIP-Seq_HELA_Human1.18029611
88FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.16690168
89E2F1_18555785_ChIP-Seq_MESCs_Mouse1.15095716
90* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14651208
91GABP_19822575_ChIP-Seq_HepG2_Human1.14576602
92* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.13891703
93SRF_21415370_ChIP-Seq_HL-1_Mouse1.13698600
94TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13419527
95* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13257366
96GATA1_19941827_ChIP-Seq_MEL_Mouse1.12382987
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.11877782
98PU_27001747_Chip-Seq_BMDM_Mouse1.11551873
99STAT6_21828071_ChIP-Seq_BEAS2B_Human1.09301216
100* EGR1_23403033_ChIP-Seq_LIVER_Mouse1.09094607
101TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09034286
102KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.08940844
103CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08501768
104MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.07123103
105TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06962459
106UTX_26944678_Chip-Seq_JUKART_Human1.06618086
107* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06102662
108* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.05738478
109BCOR_27268052_Chip-Seq_Bcells_Human1.05302295
110ELK1_22589737_ChIP-Seq_MCF10A_Human1.04757820
111NCOR1_26117541_ChIP-Seq_K562_Human1.04444802
112FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04020774
113LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.03943608
114MYB_26560356_Chip-Seq_TH1_Human1.03600186
115MYB_26560356_Chip-Seq_TH2_Human1.02463233
116HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02379174
117KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01382290
118XRN2_22483619_ChIP-Seq_HELA_Human1.00764750
119GATA1_19941826_ChIP-Seq_K562_Human1.00702145
120SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99606436
121RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98794688
122* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98565611
123POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98517379
124MAF_26560356_Chip-Seq_TH1_Human0.98282728
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.97712352
126NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.96998772
127SOX2_20726797_ChIP-Seq_SW620_Human0.96272648
128GATA1_22025678_ChIP-Seq_K562_Human0.96141074
129RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.95974322
130POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95545296
131MYCN_18555785_ChIP-Seq_MESCs_Mouse0.94117483
132PU.1_20513432_ChIP-Seq_Bcells_Mouse0.94089710
133PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93947318
134BCL6_27268052_Chip-Seq_Bcells_Human0.93739916
135ELK3_25401928_ChIP-Seq_HUVEC_Human0.93200478
136CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91733706
137KDM5A_27292631_Chip-Seq_BREAST_Human0.91526740
138RUNX1_22412390_ChIP-Seq_EML_Mouse0.89073022
139ATF3_27146783_Chip-Seq_COLON_Human0.88564723
140PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87979266
141* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.87716245
142* VDR_24763502_ChIP-Seq_THP-1_Human0.87227942
143HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.86959365
144TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.86766771
145CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.86529197
146YY1_21170310_ChIP-Seq_MESCs_Mouse0.85509119

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell3.66355776
2MP0001835_abnormal_antigen_presentation3.11465569
3MP0003436_decreased_susceptibility_to3.06384421
4MP0009785_altered_susceptibility_to2.99334526
5MP0003693_abnormal_embryo_hatching2.77556418
6MP0002148_abnormal_hypersensitivity_rea2.69868758
7MP0003724_increased_susceptibility_to2.68054276
8MP0008260_abnormal_autophagy2.60239107
9MP0006082_CNS_inflammation2.55420977
10MP0003172_abnormal_lysosome_physiology2.54813735
11MP0003303_peritoneal_inflammation2.52852559
12MP0005000_abnormal_immune_tolerance2.37458106
13MP0005451_abnormal_body_composition2.33071450
14MP0002419_abnormal_innate_immunity2.32867230
15MP0005025_abnormal_response_to2.23150245
16MP0005671_abnormal_response_to2.22609303
17MP0005058_abnormal_lysosome_morphology2.22513385
18MP0009333_abnormal_splenocyte_physiolog2.12933127
19MP0003300_gastrointestinal_ulcer2.00621138
20MP0003191_abnormal_cellular_cholesterol1.98839960
21MP0002452_abnormal_antigen_presenting1.90316194
22MP0002723_abnormal_immune_serum1.87196347
23MP0003718_maternal_effect1.85104068
24MP0003806_abnormal_nucleotide_metabolis1.84024477
25MP0001790_abnormal_immune_system1.80854843
26MP0005387_immune_system_phenotype1.80854843
27MP0009278_abnormal_bone_marrow1.79494915
28MP0003828_pulmonary_edema1.74933709
29MP0005397_hematopoietic_system_phenotyp1.72000839
30MP0001545_abnormal_hematopoietic_system1.72000839
31MP0001533_abnormal_skeleton_physiology1.71423242
32MP0003186_abnormal_redox_activity1.70100954
33MP0005365_abnormal_bile_salt1.69761184
34MP0000685_abnormal_immune_system1.69587630
35MP0001800_abnormal_humoral_immune1.69489367
36MP0010234_abnormal_vibrissa_follicle1.68444406
37MP0002254_reproductive_system_inflammat1.67675349
38MP0003448_altered_tumor_morphology1.65785036
39MP0008004_abnormal_stomach_pH1.65708695
40MP0001853_heart_inflammation1.61511518
41MP0008469_abnormal_protein_level1.61178231
42MP0004947_skin_inflammation1.60853452
43MP0009764_decreased_sensitivity_to1.60717724
44MP0004510_myositis1.60551644
45MP0001845_abnormal_inflammatory_respons1.60362038
46MP0003646_muscle_fatigue1.59510275
47MP0001819_abnormal_immune_cell1.56609335
48MP0002420_abnormal_adaptive_immunity1.52499653
49MP0003111_abnormal_nucleus_morphology1.52016494
50MP0010155_abnormal_intestine_physiology1.44072512
51MP0010307_abnormal_tumor_latency1.40358366
52MP0002405_respiratory_system_inflammati1.40126630
53MP0005310_abnormal_salivary_gland1.39457558
54MP0000343_altered_response_to1.39439760
55MP0004019_abnormal_vitamin_homeostasis1.38803616
56MP0003690_abnormal_glial_cell1.37633200
57MP0005464_abnormal_platelet_physiology1.34635380
58MP0003329_amyloid_beta_deposits1.33443601
59MP0000858_altered_metastatic_potential1.32620207
60MP0003195_calcinosis1.32066103
61MP0000716_abnormal_immune_system1.21641221
62MP0004782_abnormal_surfactant_physiolog1.21027342
63MP0003221_abnormal_cardiomyocyte_apopto1.16481530
64MP0003077_abnormal_cell_cycle1.16042342
65MP0002006_tumorigenesis1.14898210
66MP0004957_abnormal_blastocyst_morpholog1.12455969
67MP0002398_abnormal_bone_marrow1.08562194
68MP0000689_abnormal_spleen_morphology1.08508575
69MP0002277_abnormal_respiratory_mucosa1.08461801
70MP0002138_abnormal_hepatobiliary_system1.04873439
71MP0001542_abnormal_bone_strength1.02575700
72MP0002429_abnormal_blood_cell1.02191863
73MP0002722_abnormal_immune_system1.01348851
74MP0003183_abnormal_peptide_metabolism1.00782590
75MP0002132_abnormal_respiratory_system1.00601451
76MP0005319_abnormal_enzyme/_coenzyme0.99023612
77MP0005332_abnormal_amino_acid0.98735736
78MP0000609_abnormal_liver_physiology0.96800421
79MP0001756_abnormal_urination0.96565945
80MP0005167_abnormal_blood-brain_barrier0.95467969
81MP0002163_abnormal_gland_morphology0.95365132
82MP0002877_abnormal_melanocyte_morpholog0.93317659
83MP0009643_abnormal_urine_homeostasis0.93099924
84MP0002136_abnormal_kidney_physiology0.92995945
85MP0005166_decreased_susceptibility_to0.92166046
86MP0005395_other_phenotype0.91732428
87MP0000490_abnormal_crypts_of0.88807682
88MP0005085_abnormal_gallbladder_physiolo0.87689145
89MP0005666_abnormal_adipose_tissue0.87623332
90MP0004185_abnormal_adipocyte_glucose0.87578914
91MP0005165_increased_susceptibility_to0.87513116
92MP0009763_increased_sensitivity_to0.87295696
93MP0000750_abnormal_muscle_regeneration0.85954926
94MP0004883_abnormal_blood_vessel0.85946869
95MP0002139_abnormal_hepatobiliary_system0.85668769
96MP0003091_abnormal_cell_migration0.84415537
97MP0000604_amyloidosis0.84301304
98MP0003705_abnormal_hypodermis_morpholog0.84020744
99MP0008007_abnormal_cellular_replicative0.83564539
100MP0003075_altered_response_to0.83091964
101MP0002998_abnormal_bone_remodeling0.82303725
102MP0003656_abnormal_erythrocyte_physiolo0.81560953
103MP0005647_abnormal_sex_gland0.81552581
104MP0008875_abnormal_xenobiotic_pharmacok0.81149932
105MP0005390_skeleton_phenotype0.80823524
106MP0006054_spinal_hemorrhage0.79764014
107MP0000920_abnormal_myelination0.79327664
108MP0000465_gastrointestinal_hemorrhage0.78281397
109MP0003795_abnormal_bone_structure0.76546354
110MP0002166_altered_tumor_susceptibility0.76421891
111MP0005584_abnormal_enzyme/coenzyme_acti0.76111838
112MP0005164_abnormal_response_to0.75765674
113MP0004808_abnormal_hematopoietic_stem0.75654828
114MP0002118_abnormal_lipid_homeostasis0.74597831
115MP0003879_abnormal_hair_cell0.74137766
116MP0003453_abnormal_keratinocyte_physiol0.73061679
117MP0005257_abnormal_intraocular_pressure0.72828105
118MP0000627_abnormal_mammary_gland0.72749289
119MP0001851_eye_inflammation0.72088345
120MP0002396_abnormal_hematopoietic_system0.71726596
121MP0001663_abnormal_digestive_system0.70629152
122MP0002019_abnormal_tumor_incidence0.70444334
123MP0001764_abnormal_homeostasis0.70317329
124MP0000249_abnormal_blood_vessel0.69546202
125MP0000598_abnormal_liver_morphology0.69435820
126MP0005076_abnormal_cell_differentiation0.69360047
127MP0001873_stomach_inflammation0.68794063
128MP0005334_abnormal_fat_pad0.68157604
129MP0001849_ear_inflammation0.68055566
130MP0008058_abnormal_DNA_repair0.67866923
131MP0010352_gastrointestinal_tract_polyps0.66801805
132MP0005360_urolithiasis0.66279903
133MP0003786_premature_aging0.65618639
134MP0010094_abnormal_chromosome_stability0.62670801

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.21530713
2Recurrent bacterial skin infections (HP:0005406)4.94224246
3Eczematoid dermatitis (HP:0000976)4.93496953
4Abnormality of macrophages (HP:0004311)4.62787516
5Loss of speech (HP:0002371)4.45805800
6Pustule (HP:0200039)4.41061292
7Recurrent gram-negative bacterial infections (HP:0005420)4.41034041
8Mediastinal lymphadenopathy (HP:0100721)3.53643588
9Nausea (HP:0002018)3.45404435
10Abnormality of polysaccharide metabolism (HP:0011012)3.44310317
11Abnormality of glycosaminoglycan metabolism (HP:0004371)3.44310317
12Abnormality of mucopolysaccharide metabolism (HP:0011020)3.44310317
13Autoimmune thrombocytopenia (HP:0001973)3.42032049
14Vacuolated lymphocytes (HP:0001922)3.39391610
15Gout (HP:0001997)3.32673491
16Urinary glycosaminoglycan excretion (HP:0003541)3.31526777
17Mucopolysacchariduria (HP:0008155)3.31526777
18Elevated erythrocyte sedimentation rate (HP:0003565)3.27640171
19Prolonged neonatal jaundice (HP:0006579)3.27483471
20Hyperglycinuria (HP:0003108)3.18510558
21Neurofibrillary tangles (HP:0002185)3.14461870
22Complement deficiency (HP:0004431)3.12341340
23Multiple enchondromatosis (HP:0005701)3.08955879
24Hyperglycinemia (HP:0002154)3.01992924
25Myositis (HP:0100614)3.01085671
26Gingivitis (HP:0000230)2.96913009
27Osteolytic defects of the phalanges of the hand (HP:0009771)2.96161710
28Osteolytic defects of the hand bones (HP:0009699)2.96161710
29Obstructive lung disease (HP:0006536)2.94873349
30Chronic obstructive pulmonary disease (HP:0006510)2.94873349
31Purpura (HP:0000979)2.92488436
32Abnormality of liposaccharide metabolism (HP:0010968)2.91827852
33Abnormality of glycosphingolipid metabolism (HP:0004343)2.91827852
34Abnormality of glycolipid metabolism (HP:0010969)2.91827852
35Stomatitis (HP:0010280)2.89206469
36Thick nail (HP:0001805)2.84097458
37Orchitis (HP:0100796)2.83749354
38Systemic lupus erythematosus (HP:0002725)2.81472393
39Abnormality of complement system (HP:0005339)2.81237637
40Amyloidosis (HP:0011034)2.80025928
41Mutism (HP:0002300)2.77368996
42Segmental peripheral demyelination/remyelination (HP:0003481)2.77287071
43Axonal loss (HP:0003447)2.77206388
44Malnutrition (HP:0004395)2.72430437
45Nuclear cataract (HP:0100018)2.72250426
46Recurrent skin infections (HP:0001581)2.67320626
47Birth length less than 3rd percentile (HP:0003561)2.66020746
48Breast hypoplasia (HP:0003187)2.65620396
49Retrobulbar optic neuritis (HP:0100654)2.65188835
50Optic neuritis (HP:0100653)2.65188835
51Interstitial pulmonary disease (HP:0006530)2.60541690
52Basal ganglia calcification (HP:0002135)2.60366086
53Recurrent fungal infections (HP:0002841)2.59294851
54Anorexia (HP:0002039)2.51554914
55Myocardial infarction (HP:0001658)2.51428039
56Increased IgM level (HP:0003496)2.47496767
57Neuronal loss in central nervous system (HP:0002529)2.46630661
58Apathy (HP:0000741)2.45599095
59Diminished motivation (HP:0000745)2.45462699
60Abnormality of monocarboxylic acid metabolism (HP:0010996)2.45109943
61Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.43950798
62Progressive neurologic deterioration (HP:0002344)2.43806947
63Cerebral inclusion bodies (HP:0100314)2.43526048
64Polycythemia (HP:0001901)2.41500154
65Xanthomatosis (HP:0000991)2.40739234
66Prostate neoplasm (HP:0100787)2.38940665
67Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.38146254
68Entropion (HP:0000621)2.37623990
69Petechiae (HP:0000967)2.36691762
70Atrioventricular block (HP:0001678)2.34400984
71Glomerulonephritis (HP:0000099)2.33154706
72Vasculitis (HP:0002633)2.32413720
73Upper motor neuron abnormality (HP:0002127)2.31783426
74Premature loss of primary teeth (HP:0006323)2.30655910
75Abnormality of serine family amino acid metabolism (HP:0010894)2.29973935
76Abnormality of glycine metabolism (HP:0010895)2.29973935
77Carpal bone hypoplasia (HP:0001498)2.28333670
78Rough bone trabeculation (HP:0100670)2.26350413
79Increased cerebral lipofuscin (HP:0011813)2.24745025
80Muscle fiber splitting (HP:0003555)2.24151784
81Poor head control (HP:0002421)2.24007579
82Gastrointestinal infarctions (HP:0005244)2.21355701
83Pathologic fracture (HP:0002756)2.19480133
84Abnormality of iron homeostasis (HP:0011031)2.19283665
85Periodontitis (HP:0000704)2.18246262
86Chronic otitis media (HP:0000389)2.16229503
87Personality changes (HP:0000751)2.13750390
88Bone pain (HP:0002653)2.10948077
89Bundle branch block (HP:0011710)2.09478884
90Cheilitis (HP:0100825)2.08505899
91Increased neuronal autofluorescent lipopigment (HP:0002074)2.04686762
92Urticaria (HP:0001025)2.04620519
93Vertebral compression fractures (HP:0002953)2.04411226
94Peripheral demyelination (HP:0011096)2.03961304
95Asymmetric septal hypertrophy (HP:0001670)2.03282794
96Metaphyseal irregularity (HP:0003025)2.03224604
97Leukocytosis (HP:0001974)2.02564712
98Azoospermia (HP:0000027)2.01075465
99Dementia (HP:0000726)1.98623082
100Abnormality of the distal phalanges of the toes (HP:0010182)1.97913771
101Progressive visual loss (HP:0000529)1.97123198
102Abnormality of the periventricular white matter (HP:0002518)1.96796719
103Recurrent viral infections (HP:0004429)1.96534261
104Tetraparesis (HP:0002273)1.94719841
105Death in infancy (HP:0001522)1.93596717
106Abnormal trabecular bone morphology (HP:0100671)1.93263403
107Nephritis (HP:0000123)1.93187974
108Pulmonary infiltrates (HP:0002113)1.92204120
109Hepatosplenomegaly (HP:0001433)1.91989388
110Abnormal spermatogenesis (HP:0008669)1.90569768
111Impulsivity (HP:0100710)1.90396062
112Increased serum ferritin (HP:0003281)1.89187790
113Abnormality of purine metabolism (HP:0004352)1.88381754
114Abnormality of the vasculature of the conjunctiva (HP:0008054)1.88196879
115Progressive muscle weakness (HP:0003323)1.87848989
116Short nail (HP:0001799)1.87610653
117Cardiomegaly (HP:0001640)1.87334099
118Conjunctival telangiectasia (HP:0000524)1.87141346
119Increased purine levels (HP:0004368)1.85064914
120Hyperuricemia (HP:0002149)1.85064914
121Arterial thrombosis (HP:0004420)1.83942118
122Retinal atrophy (HP:0001105)1.83587644
123Cellulitis (HP:0100658)1.81977965
124Ureteral duplication (HP:0000073)1.81461685
125Abnormality of serum amino acid levels (HP:0003112)1.81237858
126Agnosia (HP:0010524)1.80322695
127Polyneuropathy (HP:0001271)1.79578286
128Disinhibition (HP:0000734)1.79423091
129Dysostosis multiplex (HP:0000943)1.79194293
130Hypergammaglobulinemia (HP:0010702)1.79054524
131IgG deficiency (HP:0004315)1.79007516
132Increased CSF protein (HP:0002922)1.78391813
133Male infertility (HP:0003251)1.77212063
134Hematochezia (HP:0002573)1.75983673
135Gingival bleeding (HP:0000225)1.75966244
136Ileus (HP:0002595)1.75540673
137Meningitis (HP:0001287)1.75344580
138Abnormality of eosinophils (HP:0001879)1.75300546
139Reduced subcutaneous adipose tissue (HP:0003758)1.74972601
140Abnormality of the umbilical cord (HP:0010881)1.74960385
141Thoracic kyphosis (HP:0002942)1.74560245
142Deep venous thrombosis (HP:0002625)1.72858942
143Keratoconjunctivitis sicca (HP:0001097)1.71867120
144Abnormality of transition element cation homeostasis (HP:0011030)1.71444847
145Hemoptysis (HP:0002105)1.68557038
146Abnormality of aromatic amino acid family metabolism (HP:0004338)1.67555280
147Restrictive lung disease (HP:0002091)1.66552984
148Hypertriglyceridemia (HP:0002155)1.66393198
149Hemorrhage of the eye (HP:0011885)1.64208696
150Skin nodule (HP:0200036)1.63049365
151Polygenic inheritance (HP:0010982)1.61962952
152Colitis (HP:0002583)1.60495397
153Splenomegaly (HP:0001744)1.59515608

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.98950060
2BUB13.54314904
3NME23.40907819
4MAP3K142.89709021
5RIPK42.79972936
6TBK12.78699373
7PRPF4B2.72588847
8TYK22.70597149
9TAOK22.46036064
10PIM22.44962196
11BLK2.43552375
12IRAK42.24820518
13IKBKB2.21769451
14WEE12.17296179
15RPS6KA42.16619940
16NEK22.00049021
17IKBKE1.87996937
18PLK41.87741384
19EPHA21.80308386
20DDR21.79687137
21FGR1.72463703
22MAP4K11.65389610
23ABL21.62333102
24ERN11.61826000
25MARK31.56717155
26MAP3K31.54943248
27ARAF1.54839469
28TESK21.54010529
29RIPK11.52922987
30AKT31.51015772
31STK31.47695174
32EIF2AK21.47399254
33BRSK21.45500003
34PBK1.43958513
35JAK31.42669056
36EIF2AK31.38487484
37CAMK1D1.35928815
38PIM11.35396227
39TXK1.34784581
40EIF2AK11.33703462
41CHUK1.32843018
42DYRK31.32021421
43MAP3K11.31055444
44STK38L1.28802946
45ZAK1.26370114
46JAK11.22816044
47SIK11.21129178
48ZAP701.20411454
49TESK11.19479244
50IRAK21.17703196
51ACVR1B1.16070505
52FGFR41.08541123
53CDC42BPA1.08278877
54NEK91.07847062
55KIT1.07763123
56STK241.07512750
57STK101.06619917
58SMG11.00677504
59BMPR20.98320129
60MOS0.97283396
61PDPK10.93961633
62MAP2K30.93751095
63TNK20.89865990
64MAP3K50.89838432
65ICK0.89762578
66PDK20.89268782
67STK160.89249239
68TGFBR20.86929336
69TAOK30.82837944
70CSF1R0.82636973
71MAP3K110.79003902
72PLK10.78440755
73CDK40.76680593
74JAK20.76217045
75TTK0.74234582
76BRAF0.73460045
77CSK0.72730827
78EPHB10.71955604
79KDR0.71025591
80RAF10.69087846
81KSR20.64452709
82PINK10.64267448
83MAP3K80.63969124
84STK40.63611275
85PRKG20.63498887
86PAK40.61469153
87PDK10.61270766
88BCKDK0.60144136
89MAP2K20.60103704
90AURKB0.59398095
91SRPK10.58428312
92NUAK10.57625915
93TSSK60.56905304
94TAOK10.56350967
95RPS6KC10.54839366
96RPS6KL10.54839366
97RPS6KA50.52998987
98LYN0.52574262
99CDK60.52224806
100PTK60.51916721
101LMTK20.51638851
102PAK10.48784253
103MST40.48553997
104GRK70.48247865
105MARK20.48219460
106PLK30.48134427
107MAP2K60.47991926
108CAMK1G0.47652178
109IRAK10.44611056
110BRSK10.44582335
111PKN20.44398445
112PRKCD0.43920727
113FES0.43876789
114PRKD20.43692243
115RPS6KA20.43310419
116NLK0.42825764
117LRRK20.42669615
118PDK30.42625638
119PDK40.42625638
120LCK0.41519127
121MATK0.39943553
122TEC0.39888167
123SIK30.39079594
124ABL10.38932530
125MAP3K130.38809809
126LATS20.37950372
127SYK0.37379720
128CHEK20.36308138
129RPS6KA60.36218707
130HCK0.35743490
131GSK3A0.35252895
132MAPK110.34178588
133MAP3K60.33683581
134MAPK70.33544523
135YES10.33521836
136MST1R0.33462199
137PRKAA20.33381563
138BMX0.33343061
139ALK0.32486411
140MKNK20.31874587
141EPHA30.31159917
142TRIB30.29580093
143MAP3K20.28999092
144BTK0.28466197
145MAPK120.27650430
146GRK60.26506051

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.03403766
2Cytosolic DNA-sensing pathway_Homo sapiens_hsa046233.09979241
3Graft-versus-host disease_Homo sapiens_hsa053322.79765971
4RNA polymerase_Homo sapiens_hsa030202.67093285
5Proteasome_Homo sapiens_hsa030502.53886239
6Staphylococcus aureus infection_Homo sapiens_hsa051502.40493185
7Legionellosis_Homo sapiens_hsa051342.38731243
8Leishmaniasis_Homo sapiens_hsa051402.38380220
9Allograft rejection_Homo sapiens_hsa053302.27574245
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.18092541
11NOD-like receptor signaling pathway_Homo sapiens_hsa046212.04821408
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.03484948
13Toll-like receptor signaling pathway_Homo sapiens_hsa046201.93190460
14Regulation of autophagy_Homo sapiens_hsa041401.87360076
15Rheumatoid arthritis_Homo sapiens_hsa053231.85940830
16Folate biosynthesis_Homo sapiens_hsa007901.79843395
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.70877331
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.69216886
19Lysosome_Homo sapiens_hsa041421.66549941
20Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.63455345
21Malaria_Homo sapiens_hsa051441.59633890
22Herpes simplex infection_Homo sapiens_hsa051681.53529679
23Measles_Homo sapiens_hsa051621.53507129
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.50205984
25Influenza A_Homo sapiens_hsa051641.48043633
26Vitamin digestion and absorption_Homo sapiens_hsa049771.43954086
27Tuberculosis_Homo sapiens_hsa051521.40670439
28Osteoclast differentiation_Homo sapiens_hsa043801.39699687
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.39100339
30Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.38056826
31Antigen processing and presentation_Homo sapiens_hsa046121.37502955
32Pertussis_Homo sapiens_hsa051331.34434769
33Type I diabetes mellitus_Homo sapiens_hsa049401.34192459
34Asthma_Homo sapiens_hsa053101.33856215
35Pyrimidine metabolism_Homo sapiens_hsa002401.32010161
36TNF signaling pathway_Homo sapiens_hsa046681.28869388
37Pentose phosphate pathway_Homo sapiens_hsa000301.20462062
38Collecting duct acid secretion_Homo sapiens_hsa049661.18475581
39Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.17007157
40p53 signaling pathway_Homo sapiens_hsa041151.15535567
41Apoptosis_Homo sapiens_hsa042101.11358902
42RNA transport_Homo sapiens_hsa030131.11232154
43African trypanosomiasis_Homo sapiens_hsa051431.11033207
44Epstein-Barr virus infection_Homo sapiens_hsa051691.10553983
45Other glycan degradation_Homo sapiens_hsa005111.09880382
46Salmonella infection_Homo sapiens_hsa051321.09298623
47Sulfur metabolism_Homo sapiens_hsa009201.08447566
48PPAR signaling pathway_Homo sapiens_hsa033201.06094187
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.05146160
50Caffeine metabolism_Homo sapiens_hsa002321.02194098
51Drug metabolism - other enzymes_Homo sapiens_hsa009831.01262320
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99823142
53Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99748335
54Vibrio cholerae infection_Homo sapiens_hsa051100.98962995
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95989303
56Jak-STAT signaling pathway_Homo sapiens_hsa046300.95215332
57Toxoplasmosis_Homo sapiens_hsa051450.92355355
58Glycerophospholipid metabolism_Homo sapiens_hsa005640.92141247
59Sulfur relay system_Homo sapiens_hsa041220.91297373
60Phagosome_Homo sapiens_hsa041450.88512604
61Bladder cancer_Homo sapiens_hsa052190.86996376
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.85147480
63Pentose and glucuronate interconversions_Homo sapiens_hsa000400.83371977
64Autoimmune thyroid disease_Homo sapiens_hsa053200.80345646
65Hematopoietic cell lineage_Homo sapiens_hsa046400.79685513
66Fatty acid biosynthesis_Homo sapiens_hsa000610.79577133
67Cell cycle_Homo sapiens_hsa041100.76045250
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75976032
69Hepatitis C_Homo sapiens_hsa051600.74745971
70Shigellosis_Homo sapiens_hsa051310.72818548
71Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70398133
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68461171
73Basal transcription factors_Homo sapiens_hsa030220.67130824
74Mineral absorption_Homo sapiens_hsa049780.66547081
75B cell receptor signaling pathway_Homo sapiens_hsa046620.66252259
76Viral myocarditis_Homo sapiens_hsa054160.66152456
77Hepatitis B_Homo sapiens_hsa051610.65188038
78Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.63751187
79Complement and coagulation cascades_Homo sapiens_hsa046100.63468076
80Adipocytokine signaling pathway_Homo sapiens_hsa049200.61379418
81Purine metabolism_Homo sapiens_hsa002300.58133882
82Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57275471
83Fructose and mannose metabolism_Homo sapiens_hsa000510.55735984
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55087096
85Base excision repair_Homo sapiens_hsa034100.53189503
86Arachidonic acid metabolism_Homo sapiens_hsa005900.52866719
87Amoebiasis_Homo sapiens_hsa051460.47277715
88Sphingolipid signaling pathway_Homo sapiens_hsa040710.46323916
89Glutathione metabolism_Homo sapiens_hsa004800.46219706
90Chemokine signaling pathway_Homo sapiens_hsa040620.45613582
91Small cell lung cancer_Homo sapiens_hsa052220.45161474
92Systemic lupus erythematosus_Homo sapiens_hsa053220.43613299
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.42819769
94Prion diseases_Homo sapiens_hsa050200.41837060
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41656819
96Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39733790
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.38872665
98VEGF signaling pathway_Homo sapiens_hsa043700.38402492
99Notch signaling pathway_Homo sapiens_hsa043300.37855871
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37256970
101Glycosaminoglycan degradation_Homo sapiens_hsa005310.37245731
102AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36448607
103Prolactin signaling pathway_Homo sapiens_hsa049170.36256035
104Insulin resistance_Homo sapiens_hsa049310.35947589
105Homologous recombination_Homo sapiens_hsa034400.35742195
106Acute myeloid leukemia_Homo sapiens_hsa052210.35243691
107Endocytosis_Homo sapiens_hsa041440.35158329
108HIF-1 signaling pathway_Homo sapiens_hsa040660.35072998
109DNA replication_Homo sapiens_hsa030300.35020320
110FoxO signaling pathway_Homo sapiens_hsa040680.34161471
111Peroxisome_Homo sapiens_hsa041460.34021764
112Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.33936845
113Galactose metabolism_Homo sapiens_hsa000520.33487113
114beta-Alanine metabolism_Homo sapiens_hsa004100.33485699
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32709727
116Pancreatic cancer_Homo sapiens_hsa052120.32394996
117Sphingolipid metabolism_Homo sapiens_hsa006000.31788117
118Phenylalanine metabolism_Homo sapiens_hsa003600.31312396
119Chronic myeloid leukemia_Homo sapiens_hsa052200.31257470
120Renin-angiotensin system_Homo sapiens_hsa046140.30769367
121Ribosome_Homo sapiens_hsa030100.30590595
122Primary immunodeficiency_Homo sapiens_hsa053400.30235109
123Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29902964
124T cell receptor signaling pathway_Homo sapiens_hsa046600.29745860
125Arginine and proline metabolism_Homo sapiens_hsa003300.29424497
126Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29107729
127Selenocompound metabolism_Homo sapiens_hsa004500.28610148
128Renal cell carcinoma_Homo sapiens_hsa052110.28042062
129Neurotrophin signaling pathway_Homo sapiens_hsa047220.27323710
130Spliceosome_Homo sapiens_hsa030400.26876269
131Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.25517107
132Fatty acid degradation_Homo sapiens_hsa000710.25045789
133Starch and sucrose metabolism_Homo sapiens_hsa005000.23581792
134Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.23082292
135Arginine biosynthesis_Homo sapiens_hsa002200.21519805

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