Rank | Gene Set | Z-score |
---|---|---|
1 | activated T cell proliferation (GO:0050798) | 6.96130183 |
2 | lens fiber cell development (GO:0070307) | 5.93341734 |
3 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.91199045 |
4 | muscle organ morphogenesis (GO:0048644) | 5.30015780 |
5 | phospholipid scrambling (GO:0017121) | 5.16265202 |
6 | interferon-gamma production (GO:0032609) | 4.85607706 |
7 | dopamine transport (GO:0015872) | 4.65586621 |
8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.52007595 |
9 | cellular response to exogenous dsRNA (GO:0071360) | 4.37959150 |
10 | platelet dense granule organization (GO:0060155) | 4.23033224 |
11 | defense response to protozoan (GO:0042832) | 4.15826427 |
12 | lymphocyte migration (GO:0072676) | 4.14235768 |
13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.13303272 |
14 | negative regulation of cell killing (GO:0031342) | 4.13303272 |
15 | positive regulation of immunoglobulin production (GO:0002639) | 4.12482408 |
16 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.09523002 |
17 | histamine transport (GO:0051608) | 4.00174558 |
18 | response to protozoan (GO:0001562) | 3.96669591 |
19 | toxin transport (GO:1901998) | 3.92125174 |
20 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.90474877 |
21 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.90474877 |
22 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.89165665 |
23 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.86237919 |
24 | UMP metabolic process (GO:0046049) | 3.86237919 |
25 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.86237919 |
26 | UMP biosynthetic process (GO:0006222) | 3.86237919 |
27 | mast cell degranulation (GO:0043303) | 3.80692096 |
28 | mast cell activation involved in immune response (GO:0002279) | 3.80692096 |
29 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.78642994 |
30 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.78642994 |
31 | leukotriene biosynthetic process (GO:0019370) | 3.78088520 |
32 | ribosomal small subunit assembly (GO:0000028) | 3.77719827 |
33 | positive regulation of defense response to virus by host (GO:0002230) | 3.74675436 |
34 | response to interferon-beta (GO:0035456) | 3.74142765 |
35 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.74051566 |
36 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.73431857 |
37 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.68638134 |
38 | regulation of antigen processing and presentation (GO:0002577) | 3.65265180 |
39 | regulation of regulatory T cell differentiation (GO:0045589) | 3.63589694 |
40 | neutrophil activation involved in immune response (GO:0002283) | 3.63204706 |
41 | cytidine metabolic process (GO:0046087) | 3.62258307 |
42 | cytidine catabolic process (GO:0006216) | 3.62258307 |
43 | cytidine deamination (GO:0009972) | 3.62258307 |
44 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.55276068 |
45 | mast cell activation (GO:0045576) | 3.54180980 |
46 | organic cation transport (GO:0015695) | 3.49331311 |
47 | purine-containing compound salvage (GO:0043101) | 3.41588568 |
48 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.41418069 |
49 | positive regulation of isotype switching (GO:0045830) | 3.39797967 |
50 | regulation of chemokine biosynthetic process (GO:0045073) | 3.39147250 |
51 | cellular response to interferon-beta (GO:0035458) | 3.37972390 |
52 | cellular response to type I interferon (GO:0071357) | 3.37635156 |
53 | type I interferon signaling pathway (GO:0060337) | 3.37635156 |
54 | regulation of B cell mediated immunity (GO:0002712) | 3.36452636 |
55 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.36342128 |
56 | regulation of gamma-delta T cell activation (GO:0046643) | 3.36078745 |
57 | response to type I interferon (GO:0034340) | 3.32176561 |
58 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.31457411 |
59 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.28033076 |
60 | proteasome assembly (GO:0043248) | 3.25231619 |
61 | positive regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.22889312 |
62 | nucleobase biosynthetic process (GO:0046112) | 3.19567590 |
63 | regulation of RIG-I signaling pathway (GO:0039535) | 3.18826782 |
64 | positive regulation of DNA recombination (GO:0045911) | 3.17394500 |
65 | cellular response to interleukin-15 (GO:0071350) | 3.15976295 |
66 | T cell lineage commitment (GO:0002360) | 3.15925753 |
67 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.13506941 |
68 | positive regulation of T cell cytokine production (GO:0002726) | 3.13197581 |
69 | regulation of chronic inflammatory response (GO:0002676) | 3.11533094 |
70 | DNA deamination (GO:0045006) | 3.10685865 |
71 | positive regulation of adaptive immune response (GO:0002821) | 3.09401948 |
72 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.06473295 |
73 | regulation of immunoglobulin production (GO:0002637) | 3.05869045 |
74 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.05182218 |
75 | negative T cell selection (GO:0043383) | 3.04754253 |
76 | motile cilium assembly (GO:0044458) | 3.04339038 |
77 | T cell migration (GO:0072678) | 3.03993148 |
78 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.02126535 |
79 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.01177087 |
80 | positive regulation of production of molecular mediator of immune response (GO:0002702) | 3.00691792 |
81 | microglial cell activation (GO:0001774) | 2.98902090 |
82 | positive regulation of interferon-alpha production (GO:0032727) | 2.98803946 |
83 | catecholamine transport (GO:0051937) | 2.98080197 |
84 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.97775673 |
85 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2.96096488 |
86 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.95082228 |
87 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.95082228 |
88 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.94740698 |
89 | NIK/NF-kappaB signaling (GO:0038061) | 2.93831670 |
90 | dendritic cell differentiation (GO:0097028) | 2.93529132 |
91 | regulation of hypersensitivity (GO:0002883) | 2.92954698 |
92 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.91299109 |
93 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.89327874 |
94 | endosome to melanosome transport (GO:0035646) | 2.88182719 |
95 | endosome to pigment granule transport (GO:0043485) | 2.88182719 |
96 | response to interferon-alpha (GO:0035455) | 2.87888169 |
97 | macrophage activation involved in immune response (GO:0002281) | 2.87386851 |
98 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.86472139 |
99 | positive regulation of activated T cell proliferation (GO:0042104) | 2.84231717 |
100 | mature B cell differentiation involved in immune response (GO:0002313) | 2.83726490 |
101 | T cell proliferation (GO:0042098) | 2.83205838 |
102 | negative thymic T cell selection (GO:0045060) | 2.81977876 |
103 | T cell activation involved in immune response (GO:0002286) | 2.81850323 |
104 | regulation of T cell tolerance induction (GO:0002664) | 2.81094010 |
105 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.80943244 |
106 | myeloid cell activation involved in immune response (GO:0002275) | 2.80794002 |
107 | response to interleukin-15 (GO:0070672) | 2.80455028 |
108 | regulation of lymphocyte mediated immunity (GO:0002706) | 2.79571888 |
109 | regulation of interferon-alpha production (GO:0032647) | 2.79259527 |
110 | regulation of response to interferon-gamma (GO:0060330) | 2.79218469 |
111 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.78800091 |
112 | immunoglobulin mediated immune response (GO:0016064) | 2.78564407 |
113 | base-excision repair, AP site formation (GO:0006285) | 2.77313059 |
114 | regulation of adaptive immune response based on somatic recombination of immune receptors built from | 2.75628638 |
115 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.72086340 |
116 | cytolysis (GO:0019835) | 2.70734521 |
117 | leukocyte degranulation (GO:0043299) | 2.70323846 |
118 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.69313480 |
119 | ovulation from ovarian follicle (GO:0001542) | 2.65894536 |
120 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.65369467 |
121 | regulation of adaptive immune response (GO:0002819) | 2.65067687 |
122 | arginine catabolic process (GO:0006527) | 2.64189278 |
123 | positive regulation of antigen processing and presentation (GO:0002579) | 2.63836260 |
124 | regulation of defense response to virus by host (GO:0050691) | 2.63269660 |
125 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.63035979 |
126 | regulation of T cell cytokine production (GO:0002724) | 2.62885037 |
127 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.62241504 |
128 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.60195339 |
129 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.59711981 |
130 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.59649453 |
131 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.58828524 |
132 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.58588324 |
133 | lysosome localization (GO:0032418) | 2.58383052 |
134 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.58112074 |
135 | T-helper cell differentiation (GO:0042093) | 2.58112074 |
136 | cytokine production involved in immune response (GO:0002367) | 2.57249882 |
137 | cellular response to zinc ion (GO:0071294) | 2.57147337 |
138 | regulation of activation of Janus kinase activity (GO:0010533) | 2.56237391 |
139 | B cell mediated immunity (GO:0019724) | 2.53779339 |
140 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.53524130 |
141 | regulation of isotype switching (GO:0045191) | 2.53362730 |
142 | negative regulation of viral genome replication (GO:0045071) | 2.52849889 |
143 | negative regulation of phagocytosis (GO:0050765) | 2.51898335 |
144 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.51736187 |
145 | positive regulation of B cell mediated immunity (GO:0002714) | 2.51736187 |
146 | myeloid dendritic cell activation (GO:0001773) | 2.51160313 |
147 | neutrophil activation (GO:0042119) | 2.51007517 |
148 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 2.50763202 |
149 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.48179538 |
150 | production of molecular mediator of immune response (GO:0002440) | 2.47449718 |
151 | ubiquinone biosynthetic process (GO:0006744) | 2.47126552 |
152 | quinone biosynthetic process (GO:1901663) | 2.47126552 |
153 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.46631393 |
154 | respiratory burst (GO:0045730) | 2.43914803 |
155 | viral transcription (GO:0019083) | 2.42057032 |
156 | mature B cell differentiation (GO:0002335) | 2.40715818 |
157 | cytokine secretion (GO:0050663) | 2.36324616 |
158 | regulation of natural killer cell differentiation (GO:0032823) | 2.35156462 |
159 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.35051121 |
160 | positive regulation of interferon-beta production (GO:0032728) | 2.32041707 |
161 | translational termination (GO:0006415) | 2.31846299 |
162 | myeloid dendritic cell differentiation (GO:0043011) | 2.31828691 |
163 | positive regulation of B cell differentiation (GO:0045579) | 2.31659909 |
164 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.31597632 |
165 | T cell differentiation involved in immune response (GO:0002292) | 2.31597632 |
166 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.31597632 |
167 | response to mercury ion (GO:0046689) | 2.31214787 |
168 | rRNA transcription (GO:0009303) | 2.30885861 |
169 | regulation of T-helper cell differentiation (GO:0045622) | 2.30590040 |
170 | granulocyte activation (GO:0036230) | 2.30224918 |
171 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.29984664 |
172 | regulation of necroptotic process (GO:0060544) | 2.28178849 |
173 | purine nucleobase metabolic process (GO:0006144) | 2.28136883 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.84535060 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.76976392 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.18247186 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.61766519 |
5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.28317106 |
6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.20587686 |
7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.17667364 |
8 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 3.05868362 |
9 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.96774150 |
10 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.74363433 |
11 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.61483410 |
12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.56655001 |
13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.54365395 |
14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.53956827 |
15 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.42113095 |
16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.33158686 |
17 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.32963823 |
18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.31954411 |
19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.30480933 |
20 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.24085837 |
21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.23610096 |
22 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.16919249 |
23 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.12510959 |
24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.09156136 |
25 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.08936635 |
26 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.04877557 |
27 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.04440327 |
28 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.02212641 |
29 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.02130803 |
30 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91242830 |
31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.89796980 |
32 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.88669194 |
33 | GATA1_22025678_ChIP-Seq_K562_Human | 1.81989214 |
34 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.81738201 |
35 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.80763778 |
36 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.78611840 |
37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.78362461 |
38 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.77766979 |
39 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.76298716 |
40 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.75322799 |
41 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.74396813 |
42 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73402132 |
43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.71474413 |
44 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.69391466 |
45 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.68352281 |
46 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.61909718 |
47 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.61445349 |
48 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.57964563 |
49 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57007934 |
50 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56578111 |
51 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.56177956 |
52 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.53287356 |
53 | MYB_26560356_Chip-Seq_TH2_Human | 1.52553987 |
54 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.51752212 |
55 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.48837726 |
56 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.46628216 |
57 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.44974987 |
58 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.44190905 |
59 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.41970370 |
60 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.41291809 |
61 | MYB_26560356_Chip-Seq_TH1_Human | 1.39852696 |
62 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38963119 |
63 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.38393710 |
64 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36679115 |
65 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.35679117 |
66 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.32953154 |
67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.31978286 |
68 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.31146317 |
69 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.30359510 |
70 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.29752242 |
71 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.28717788 |
72 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.27900554 |
73 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.27458863 |
74 | MAF_26560356_Chip-Seq_TH1_Human | 1.26542328 |
75 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.26485825 |
76 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25250881 |
77 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.23701367 |
78 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.23681976 |
79 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23625062 |
80 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.22777493 |
81 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.21136455 |
82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20806293 |
83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20806293 |
84 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.20459007 |
85 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.20258468 |
86 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.19863888 |
87 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.17564727 |
88 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16197530 |
89 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16087182 |
90 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.15441912 |
91 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.13242116 |
92 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.12717851 |
93 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.12303421 |
94 | GATA3_26560356_Chip-Seq_TH1_Human | 1.11570329 |
95 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.11309477 |
96 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.10464823 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.09014805 |
98 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.07821812 |
99 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.07563764 |
100 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.07336106 |
101 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07258757 |
102 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.07064145 |
103 | MAF_26560356_Chip-Seq_TH2_Human | 1.06267970 |
104 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.05941348 |
105 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.05442455 |
106 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04938423 |
107 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.04599161 |
108 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.04306850 |
109 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04293607 |
110 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.04254421 |
111 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.04243961 |
112 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04174941 |
113 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.04034620 |
114 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.03857552 |
115 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.03392038 |
116 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02886105 |
117 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.02083417 |
118 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.01838045 |
119 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.00729296 |
120 | SPI1_23127762_ChIP-Seq_K562_Human | 1.00381079 |
121 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.00195816 |
122 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99779953 |
123 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98636708 |
124 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98636708 |
125 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97516726 |
126 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97409293 |
127 | UTX_26944678_Chip-Seq_JUKART_Human | 0.97011550 |
128 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96401820 |
129 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.95721461 |
130 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.95103262 |
131 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.94337000 |
132 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.93401235 |
133 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.91188296 |
134 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90467528 |
135 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.90080823 |
136 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.89766057 |
137 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.89758302 |
138 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.88868902 |
139 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.88651553 |
140 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.88168205 |
141 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.86873906 |
142 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.85937505 |
143 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85873186 |
144 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.85119475 |
145 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.84945413 |
146 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.84847431 |
147 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.84368702 |
148 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.83827083 |
149 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.83534602 |
150 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.81122770 |
151 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.80152510 |
152 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.79455739 |
153 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.79329422 |
154 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.78856833 |
155 | AR_20517297_ChIP-Seq_VCAP_Human | 0.78613238 |
156 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.78420818 |
157 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.78358266 |
158 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.76864704 |
159 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.75901392 |
160 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.75297823 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002132_abnormal_respiratory_system | 5.15021336 |
2 | MP0001835_abnormal_antigen_presentation | 4.44300504 |
3 | MP0009785_altered_susceptibility_to | 3.14539777 |
4 | MP0000685_abnormal_immune_system | 3.12856207 |
5 | MP0001348_abnormal_lacrimal_gland | 2.97931043 |
6 | MP0006082_CNS_inflammation | 2.89445204 |
7 | MP0002148_abnormal_hypersensitivity_rea | 2.68872686 |
8 | MP0005671_abnormal_response_to | 2.65196832 |
9 | MP0005310_abnormal_salivary_gland | 2.63576712 |
10 | MP0005408_hypopigmentation | 2.56867006 |
11 | MP0001873_stomach_inflammation | 2.51723470 |
12 | MP0001853_heart_inflammation | 2.47221740 |
13 | MP0005025_abnormal_response_to | 2.46322270 |
14 | MP0001790_abnormal_immune_system | 2.38478697 |
15 | MP0005387_immune_system_phenotype | 2.38478697 |
16 | MP0004510_myositis | 2.36819576 |
17 | MP0005000_abnormal_immune_tolerance | 2.36377377 |
18 | MP0003436_decreased_susceptibility_to | 2.36059124 |
19 | MP0002419_abnormal_innate_immunity | 2.27626731 |
20 | MP0001800_abnormal_humoral_immune | 2.27313382 |
21 | MP0002452_abnormal_antigen_presenting | 2.21284748 |
22 | MP0002723_abnormal_immune_serum | 2.12207372 |
23 | MP0003724_increased_susceptibility_to | 2.06565223 |
24 | MP0001819_abnormal_immune_cell | 2.01802835 |
25 | MP0002420_abnormal_adaptive_immunity | 2.00992022 |
26 | MP0002396_abnormal_hematopoietic_system | 2.00709228 |
27 | MP0005464_abnormal_platelet_physiology | 1.95339167 |
28 | MP0003300_gastrointestinal_ulcer | 1.94834618 |
29 | MP0005167_abnormal_blood-brain_barrier | 1.92156609 |
30 | MP0002166_altered_tumor_susceptibility | 1.90873325 |
31 | MP0009840_abnormal_foam_cell | 1.84434915 |
32 | MP0003186_abnormal_redox_activity | 1.77050951 |
33 | MP0003763_abnormal_thymus_physiology | 1.74217388 |
34 | MP0002006_tumorigenesis | 1.73710951 |
35 | MP0002398_abnormal_bone_marrow | 1.72794686 |
36 | MP0003693_abnormal_embryo_hatching | 1.70865578 |
37 | MP0008438_abnormal_cutaneous_collagen | 1.70837879 |
38 | MP0010155_abnormal_intestine_physiology | 1.68067163 |
39 | MP0000716_abnormal_immune_system | 1.67235044 |
40 | MP0009333_abnormal_splenocyte_physiolog | 1.64603876 |
41 | MP0002405_respiratory_system_inflammati | 1.62740987 |
42 | MP0005058_abnormal_lysosome_morphology | 1.60973341 |
43 | MP0008469_abnormal_protein_level | 1.59018184 |
44 | MP0001845_abnormal_inflammatory_respons | 1.58456909 |
45 | MP0003195_calcinosis | 1.57514488 |
46 | MP0000689_abnormal_spleen_morphology | 1.55451879 |
47 | MP0009697_abnormal_copulation | 1.54823793 |
48 | MP0002332_abnormal_exercise_endurance | 1.50588226 |
49 | MP0002722_abnormal_immune_system | 1.45864631 |
50 | MP0002429_abnormal_blood_cell | 1.43181471 |
51 | MP0003191_abnormal_cellular_cholesterol | 1.42703576 |
52 | MP0002837_dystrophic_cardiac_calcinosis | 1.37082407 |
53 | MP0004883_abnormal_blood_vessel | 1.36965229 |
54 | MP0009764_decreased_sensitivity_to | 1.36130098 |
55 | MP0004947_skin_inflammation | 1.35906498 |
56 | MP0003866_abnormal_defecation | 1.31936952 |
57 | MP0003045_fibrosis | 1.29164915 |
58 | MP0000343_altered_response_to | 1.28065271 |
59 | MP0001545_abnormal_hematopoietic_system | 1.26425361 |
60 | MP0005397_hematopoietic_system_phenotyp | 1.26425361 |
61 | MP0001533_abnormal_skeleton_physiology | 1.26362400 |
62 | MP0004808_abnormal_hematopoietic_stem | 1.24392494 |
63 | MP0003252_abnormal_bile_duct | 1.24112014 |
64 | MP0002163_abnormal_gland_morphology | 1.22335391 |
65 | MP0002876_abnormal_thyroid_physiology | 1.17315845 |
66 | MP0003690_abnormal_glial_cell | 1.16569059 |
67 | MP0001663_abnormal_digestive_system | 1.12916032 |
68 | MP0001986_abnormal_taste_sensitivity | 1.09750435 |
69 | MP0003448_altered_tumor_morphology | 1.08700764 |
70 | MP0009763_increased_sensitivity_to | 1.08673884 |
71 | MP0005379_endocrine/exocrine_gland_phen | 1.07745760 |
72 | MP0002277_abnormal_respiratory_mucosa | 1.07187568 |
73 | MP0003172_abnormal_lysosome_physiology | 1.06118053 |
74 | MP0005166_decreased_susceptibility_to | 1.03679830 |
75 | MP0002693_abnormal_pancreas_physiology | 1.03653643 |
76 | MP0002138_abnormal_hepatobiliary_system | 1.03521053 |
77 | MP0000490_abnormal_crypts_of | 1.01649835 |
78 | MP0000858_altered_metastatic_potential | 1.00203291 |
79 | MP0009765_abnormal_xenobiotic_induced | 0.98641426 |
80 | MP0005075_abnormal_melanosome_morpholog | 0.97040453 |
81 | MP0000465_gastrointestinal_hemorrhage | 0.96822260 |
82 | MP0001727_abnormal_embryo_implantation | 0.94672883 |
83 | MP0004957_abnormal_blastocyst_morpholog | 0.94564982 |
84 | MP0004142_abnormal_muscle_tone | 0.93684367 |
85 | MP0001764_abnormal_homeostasis | 0.92269234 |
86 | MP0008058_abnormal_DNA_repair | 0.89137009 |
87 | MP0003718_maternal_effect | 0.89123154 |
88 | MP0003786_premature_aging | 0.89115809 |
89 | MP0009643_abnormal_urine_homeostasis | 0.89064460 |
90 | MP0000703_abnormal_thymus_morphology | 0.89034476 |
91 | MP0003221_abnormal_cardiomyocyte_apopto | 0.88451850 |
92 | MP0005319_abnormal_enzyme/_coenzyme | 0.88185288 |
93 | MP0002933_joint_inflammation | 0.86887864 |
94 | MP0010368_abnormal_lymphatic_system | 0.86626573 |
95 | MP0003566_abnormal_cell_adhesion | 0.86540992 |
96 | MP0001851_eye_inflammation | 0.86367844 |
97 | MP0003828_pulmonary_edema | 0.86241768 |
98 | MP0002998_abnormal_bone_remodeling | 0.85090415 |
99 | MP0010329_abnormal_lipoprotein_level | 0.85014923 |
100 | MP0003806_abnormal_nucleotide_metabolis | 0.84856236 |
101 | MP0000249_abnormal_blood_vessel | 0.84850408 |
102 | MP0001905_abnormal_dopamine_level | 0.84449237 |
103 | MP0002928_abnormal_bile_duct | 0.83844930 |
104 | MP0006054_spinal_hemorrhage | 0.82350580 |
105 | MP0000609_abnormal_liver_physiology | 0.81478235 |
106 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.81378957 |
107 | MP0008007_abnormal_cellular_replicative | 0.80600482 |
108 | MP0002095_abnormal_skin_pigmentation | 0.79268667 |
109 | MP0002019_abnormal_tumor_incidence | 0.78958526 |
110 | MP0003646_muscle_fatigue | 0.78245878 |
111 | MP0003950_abnormal_plasma_membrane | 0.76958575 |
112 | MP0005083_abnormal_biliary_tract | 0.76378977 |
113 | MP0006036_abnormal_mitochondrial_physio | 0.75978788 |
114 | MP0002136_abnormal_kidney_physiology | 0.75859277 |
115 | MP0005085_abnormal_gallbladder_physiolo | 0.74532106 |
116 | MP0005165_increased_susceptibility_to | 0.74104162 |
117 | MP0002139_abnormal_hepatobiliary_system | 0.73795618 |
118 | MP0003638_abnormal_response/metabolism_ | 0.73783000 |
119 | MP0003656_abnormal_erythrocyte_physiolo | 0.73395330 |
120 | MP0004782_abnormal_surfactant_physiolog | 0.73095409 |
121 | MP0005595_abnormal_vascular_smooth | 0.73009043 |
122 | MP0003303_peritoneal_inflammation | 0.72254085 |
123 | MP0000015_abnormal_ear_pigmentation | 0.72005218 |
124 | MP0003077_abnormal_cell_cycle | 0.71768985 |
125 | MP0005376_homeostasis/metabolism_phenot | 0.71759018 |
126 | MP0002254_reproductive_system_inflammat | 0.71158887 |
127 | MP0005266_abnormal_metabolism | 0.70624910 |
128 | MP0005174_abnormal_tail_pigmentation | 0.70351654 |
129 | MP0008875_abnormal_xenobiotic_pharmacok | 0.70158516 |
130 | MP0005164_abnormal_response_to | 0.70132346 |
131 | MP0003075_altered_response_to | 0.70018377 |
132 | MP0005360_urolithiasis | 0.69960483 |
133 | MP0000372_irregular_coat_pigmentation | 0.69437472 |
134 | MP0000569_abnormal_digit_pigmentation | 0.66319343 |
135 | MP0001765_abnormal_ion_homeostasis | 0.65824540 |
136 | MP0005636_abnormal_mineral_homeostasis | 0.65442846 |
137 | MP0001756_abnormal_urination | 0.63646785 |
138 | MP0005381_digestive/alimentary_phenotyp | 0.62709186 |
139 | MP0005410_abnormal_fertilization | 0.61661269 |
140 | MP0005395_other_phenotype | 0.60257166 |
141 | MP0000230_abnormal_systemic_arterial | 0.60129992 |
142 | MP0003879_abnormal_hair_cell | 0.56944298 |
143 | MP0005647_abnormal_sex_gland | 0.55137716 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Zonular cataract (HP:0010920) | 5.48354085 |
2 | Nasal polyposis (HP:0100582) | 5.30640046 |
3 | Abnormality of the nasal mucosa (HP:0000433) | 4.85860022 |
4 | Abnormality of pyrimidine metabolism (HP:0004353) | 4.57759369 |
5 | Autoimmune thrombocytopenia (HP:0001973) | 4.28817719 |
6 | Recurrent abscess formation (HP:0002722) | 4.23019608 |
7 | Recurrent bacterial skin infections (HP:0005406) | 3.99580884 |
8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.98768734 |
9 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.96886093 |
10 | Eczematoid dermatitis (HP:0000976) | 3.79106486 |
11 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.68943444 |
12 | Absent/shortened dynein arms (HP:0200106) | 3.68943444 |
13 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 3.63920506 |
14 | Myositis (HP:0100614) | 3.51076016 |
15 | Thrombocytosis (HP:0001894) | 3.43960754 |
16 | Abnormality of macrophages (HP:0004311) | 3.42299888 |
17 | Megaloblastic anemia (HP:0001889) | 3.36231406 |
18 | Progressive muscle weakness (HP:0003323) | 3.29639838 |
19 | Vacuolated lymphocytes (HP:0001922) | 3.20787351 |
20 | IgM deficiency (HP:0002850) | 3.17687113 |
21 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.08814042 |
22 | Autoimmune hemolytic anemia (HP:0001890) | 3.01498120 |
23 | T lymphocytopenia (HP:0005403) | 2.98542870 |
24 | Hypoproteinemia (HP:0003075) | 2.95898775 |
25 | Hemiplegia (HP:0002301) | 2.90276292 |
26 | Systemic lupus erythematosus (HP:0002725) | 2.83460796 |
27 | Recurrent fungal infections (HP:0002841) | 2.83360250 |
28 | Abnormal number of erythroid precursors (HP:0012131) | 2.82471588 |
29 | Chronic otitis media (HP:0000389) | 2.81064655 |
30 | Petechiae (HP:0000967) | 2.77181664 |
31 | Stomach cancer (HP:0012126) | 2.73628539 |
32 | Eosinophilia (HP:0001880) | 2.72859347 |
33 | Orchitis (HP:0100796) | 2.72727404 |
34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.72559073 |
35 | Recurrent skin infections (HP:0001581) | 2.71491323 |
36 | Mediastinal lymphadenopathy (HP:0100721) | 2.69913067 |
37 | Attenuation of retinal blood vessels (HP:0007843) | 2.69414287 |
38 | Abnormality of the anterior horn cell (HP:0006802) | 2.65054821 |
39 | Degeneration of anterior horn cells (HP:0002398) | 2.65054821 |
40 | Ragged-red muscle fibers (HP:0003200) | 2.64965950 |
41 | Reduced antithrombin III activity (HP:0001976) | 2.64598619 |
42 | Recurrent viral infections (HP:0004429) | 2.62392146 |
43 | Granulocytopenia (HP:0001913) | 2.62024075 |
44 | Cheilitis (HP:0100825) | 2.59477475 |
45 | Increased IgM level (HP:0003496) | 2.59340308 |
46 | Striae distensae (HP:0001065) | 2.55699032 |
47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.53786932 |
48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.53786932 |
49 | Vertebral compression fractures (HP:0002953) | 2.52973391 |
50 | Spinal muscular atrophy (HP:0007269) | 2.52520276 |
51 | Vasculitis (HP:0002633) | 2.51372431 |
52 | Hypsarrhythmia (HP:0002521) | 2.50022610 |
53 | Abnormality of T cell physiology (HP:0011840) | 2.49856108 |
54 | J-shaped sella turcica (HP:0002680) | 2.49211723 |
55 | EEG with generalized epileptiform discharges (HP:0011198) | 2.44855060 |
56 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.43652942 |
57 | Recurrent cutaneous fungal infections (HP:0011370) | 2.43652942 |
58 | Basal ganglia calcification (HP:0002135) | 2.42252182 |
59 | Pustule (HP:0200039) | 2.41330242 |
60 | Optic neuritis (HP:0100653) | 2.40980354 |
61 | Retrobulbar optic neuritis (HP:0100654) | 2.40980354 |
62 | Epileptiform EEG discharges (HP:0011182) | 2.39707601 |
63 | IgG deficiency (HP:0004315) | 2.39646717 |
64 | Abnormality of eosinophils (HP:0001879) | 2.38151134 |
65 | Hypergammaglobulinemia (HP:0010702) | 2.36690749 |
66 | Recurrent bronchitis (HP:0002837) | 2.35930243 |
67 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.35651098 |
68 | Impaired platelet aggregation (HP:0003540) | 2.35258108 |
69 | Abnormal platelet function (HP:0011869) | 2.35258108 |
70 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.34485701 |
71 | Osteolytic defects of the hand bones (HP:0009699) | 2.34485701 |
72 | Hemoptysis (HP:0002105) | 2.33830126 |
73 | Delayed CNS myelination (HP:0002188) | 2.32994991 |
74 | Abnormality of glycolipid metabolism (HP:0010969) | 2.30465438 |
75 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.30465438 |
76 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.30465438 |
77 | Hematochezia (HP:0002573) | 2.29246373 |
78 | Chronic obstructive pulmonary disease (HP:0006510) | 2.28978705 |
79 | Obstructive lung disease (HP:0006536) | 2.28978705 |
80 | Atrioventricular block (HP:0001678) | 2.27280118 |
81 | Meningitis (HP:0001287) | 2.26079049 |
82 | Leukocytosis (HP:0001974) | 2.24331266 |
83 | Increased circulating renin level (HP:0000848) | 2.23581840 |
84 | Constricted visual fields (HP:0001133) | 2.23049372 |
85 | Congenital stationary night blindness (HP:0007642) | 2.22944933 |
86 | Albinism (HP:0001022) | 2.21158551 |
87 | Severe combined immunodeficiency (HP:0004430) | 2.21033736 |
88 | Cellulitis (HP:0100658) | 2.20936148 |
89 | Parakeratosis (HP:0001036) | 2.19275908 |
90 | IgA deficiency (HP:0002720) | 2.18375924 |
91 | Abnormality of T cells (HP:0002843) | 2.16714077 |
92 | Abnormality of the prostate (HP:0008775) | 2.16090993 |
93 | Epistaxis (HP:0000421) | 2.14559049 |
94 | Facial diplegia (HP:0001349) | 2.13629098 |
95 | Prolonged neonatal jaundice (HP:0006579) | 2.12997804 |
96 | Purpura (HP:0000979) | 2.12454458 |
97 | Exertional dyspnea (HP:0002875) | 2.11908593 |
98 | Hypoalbuminemia (HP:0003073) | 2.11881407 |
99 | Abnormal albumin level (HP:0012116) | 2.11881407 |
100 | Combined immunodeficiency (HP:0005387) | 2.10457779 |
101 | Spastic paraparesis (HP:0002313) | 2.10143625 |
102 | Stomatitis (HP:0010280) | 2.09981611 |
103 | Abnormality of macular pigmentation (HP:0008002) | 2.09857545 |
104 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.09190568 |
105 | B lymphocytopenia (HP:0010976) | 2.09026446 |
106 | Abnormality of B cell number (HP:0010975) | 2.09026446 |
107 | Prolonged bleeding time (HP:0003010) | 2.08537156 |
108 | Lymphopenia (HP:0001888) | 2.07762699 |
109 | Gastrointestinal infarctions (HP:0005244) | 2.07405548 |
110 | Conjugated hyperbilirubinemia (HP:0002908) | 2.06891885 |
111 | Pancytopenia (HP:0001876) | 2.04652865 |
112 | Gingival bleeding (HP:0000225) | 2.03736383 |
113 | Interstitial pulmonary disease (HP:0006530) | 2.03341802 |
114 | Abnormality of iron homeostasis (HP:0011031) | 2.02041013 |
115 | Increased IgE level (HP:0003212) | 2.01623761 |
116 | Hepatosplenomegaly (HP:0001433) | 2.01032962 |
117 | Stridor (HP:0010307) | 2.00981902 |
118 | Scanning speech (HP:0002168) | 1.99925278 |
119 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.98077813 |
120 | Nausea (HP:0002018) | 1.96809409 |
121 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.96723828 |
122 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.96723828 |
123 | Microcytic anemia (HP:0001935) | 1.95375643 |
124 | Poikilocytosis (HP:0004447) | 1.95096036 |
125 | Agitation (HP:0000713) | 1.94964435 |
126 | Type I transferrin isoform profile (HP:0003642) | 1.94868808 |
127 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.93349445 |
128 | Chest pain (HP:0100749) | 1.92304858 |
129 | Periodontitis (HP:0000704) | 1.92063540 |
130 | Poor head control (HP:0002421) | 1.91603300 |
131 | Pulmonary infiltrates (HP:0002113) | 1.91096370 |
132 | Keratoconjunctivitis (HP:0001096) | 1.89183511 |
133 | 3-Methylglutaconic aciduria (HP:0003535) | 1.88760613 |
134 | Agammaglobulinemia (HP:0004432) | 1.87360974 |
135 | Encephalitis (HP:0002383) | 1.86620304 |
136 | Toxemia of pregnancy (HP:0100603) | 1.85835851 |
137 | Beaking of vertebral bodies (HP:0004568) | 1.85703025 |
138 | Urticaria (HP:0001025) | 1.85112958 |
139 | Arterial thrombosis (HP:0004420) | 1.84884316 |
140 | Pulmonary embolism (HP:0002204) | 1.83718712 |
141 | Abnormality of T cell number (HP:0011839) | 1.83460465 |
142 | Hepatic necrosis (HP:0002605) | 1.82775968 |
143 | Thyroiditis (HP:0100646) | 1.81892921 |
144 | Chronic diarrhea (HP:0002028) | 1.81875572 |
145 | Panhypogammaglobulinemia (HP:0003139) | 1.81358122 |
146 | Keratoconjunctivitis sicca (HP:0001097) | 1.81055692 |
147 | Increased CSF protein (HP:0002922) | 1.81005768 |
148 | Increased serum ferritin (HP:0003281) | 1.80136555 |
149 | Abnormal drinking behavior (HP:0030082) | 1.78873366 |
150 | Polydipsia (HP:0001959) | 1.78873366 |
151 | Spontaneous hematomas (HP:0007420) | 1.78139354 |
152 | Respiratory distress (HP:0002098) | 1.77773346 |
153 | Reticulocytopenia (HP:0001896) | 1.77618306 |
154 | Recurrent pneumonia (HP:0006532) | 1.77143038 |
155 | Diaphragmatic weakness (HP:0009113) | 1.75185702 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ITK | 5.00547891 |
2 | PTK2B | 3.43168022 |
3 | MAP4K1 | 3.27488340 |
4 | STK16 | 3.18998103 |
5 | FES | 3.02785703 |
6 | IRAK4 | 2.62852767 |
7 | FRK | 2.59258913 |
8 | MAP3K14 | 2.58630281 |
9 | NME2 | 2.57532315 |
10 | PIM2 | 2.57227941 |
11 | KIT | 2.46502034 |
12 | TBK1 | 2.39870618 |
13 | TYK2 | 2.37478769 |
14 | TXK | 2.30940517 |
15 | EIF2AK1 | 2.26980741 |
16 | ADRBK2 | 2.17173123 |
17 | IKBKE | 2.16173754 |
18 | IKBKB | 2.13603977 |
19 | IRAK3 | 2.13151335 |
20 | MAP3K12 | 2.11424730 |
21 | NEK9 | 2.07088213 |
22 | WNK4 | 2.02864798 |
23 | MUSK | 2.02500147 |
24 | EIF2AK3 | 1.96367373 |
25 | TGFBR2 | 1.87574452 |
26 | KDR | 1.77428693 |
27 | BUB1 | 1.73115751 |
28 | TEC | 1.70225290 |
29 | BLK | 1.67729451 |
30 | MYLK | 1.65949877 |
31 | WEE1 | 1.62417374 |
32 | ZAP70 | 1.60814349 |
33 | PIM1 | 1.60194426 |
34 | JAK3 | 1.57517788 |
35 | CHUK | 1.55012989 |
36 | BCKDK | 1.54381883 |
37 | RIPK4 | 1.53084428 |
38 | TLK1 | 1.52418741 |
39 | CSF1R | 1.52369754 |
40 | ERN1 | 1.50074223 |
41 | PLK4 | 1.36521808 |
42 | MAPK7 | 1.36152392 |
43 | STK24 | 1.34338736 |
44 | MAP3K13 | 1.31376973 |
45 | BTK | 1.31026362 |
46 | GSK3A | 1.29461980 |
47 | ACVR1B | 1.25469275 |
48 | SYK | 1.22675540 |
49 | STK39 | 1.22198623 |
50 | GRK1 | 1.21908862 |
51 | CDK9 | 1.19492872 |
52 | JAK1 | 1.18138451 |
53 | MAP2K3 | 1.17308903 |
54 | STK4 | 1.13654647 |
55 | EIF2AK2 | 1.13016318 |
56 | RPS6KA4 | 1.10867147 |
57 | RPS6KA5 | 1.10016943 |
58 | PDGFRB | 1.09843690 |
59 | MAP3K7 | 1.09393257 |
60 | MKNK1 | 1.02971663 |
61 | PINK1 | 0.98985152 |
62 | FGFR4 | 0.97573830 |
63 | TGFBR1 | 0.97534387 |
64 | LRRK2 | 0.92499456 |
65 | LYN | 0.91664186 |
66 | PRKCQ | 0.90731335 |
67 | SRPK1 | 0.89964441 |
68 | MAP4K2 | 0.88971506 |
69 | STK10 | 0.88632336 |
70 | FLT3 | 0.88427215 |
71 | LCK | 0.84483784 |
72 | TESK2 | 0.82785634 |
73 | MAP3K3 | 0.79267267 |
74 | BMPR2 | 0.77216841 |
75 | VRK1 | 0.75601957 |
76 | MATK | 0.74642887 |
77 | MKNK2 | 0.71185139 |
78 | PAK4 | 0.69629614 |
79 | CSK | 0.66744097 |
80 | MAP2K6 | 0.65912554 |
81 | GRK7 | 0.65483252 |
82 | INSRR | 0.63904101 |
83 | ADRBK1 | 0.61188451 |
84 | BMPR1B | 0.60880521 |
85 | IRAK1 | 0.59005486 |
86 | PIK3CG | 0.58591794 |
87 | FER | 0.58490667 |
88 | PRKAA2 | 0.58405938 |
89 | DYRK3 | 0.57661092 |
90 | FGR | 0.57153945 |
91 | WNK3 | 0.55144380 |
92 | CDK4 | 0.54662023 |
93 | PRKCZ | 0.54439662 |
94 | PIK3CA | 0.53793368 |
95 | ABL2 | 0.53731239 |
96 | MARK3 | 0.52449577 |
97 | DAPK2 | 0.52213428 |
98 | MST4 | 0.52095443 |
99 | CSNK1A1 | 0.51485403 |
100 | HCK | 0.50890639 |
101 | MAPKAPK5 | 0.50018879 |
102 | IGF1R | 0.49160504 |
103 | EPHB1 | 0.48576905 |
104 | ABL1 | 0.48555461 |
105 | CAMKK2 | 0.48537212 |
106 | AURKB | 0.48466570 |
107 | ILK | 0.47983762 |
108 | TIE1 | 0.47970162 |
109 | DAPK1 | 0.47818700 |
110 | INSR | 0.47587043 |
111 | TAOK3 | 0.45527255 |
112 | PRKCD | 0.45125532 |
113 | PRKG2 | 0.44784031 |
114 | JAK2 | 0.44487852 |
115 | TRPM7 | 0.43749328 |
116 | ZAK | 0.43746820 |
117 | STK3 | 0.43487956 |
118 | TNK2 | 0.43289648 |
119 | CHEK2 | 0.42864290 |
120 | NLK | 0.42608969 |
121 | CDK8 | 0.42244100 |
122 | MAPKAPK2 | 0.38807543 |
123 | PDK1 | 0.38271212 |
124 | MOS | 0.38261070 |
125 | BRSK2 | 0.37379703 |
126 | STK38 | 0.37153724 |
127 | MAPKAPK3 | 0.36625761 |
128 | MAP3K8 | 0.36200435 |
129 | GRK5 | 0.35847939 |
130 | FYN | 0.35732938 |
131 | MAP3K11 | 0.35681409 |
132 | PAK3 | 0.35246993 |
133 | PASK | 0.34828654 |
134 | CDK19 | 0.33177796 |
135 | NEK2 | 0.33171983 |
136 | MAPK11 | 0.32760965 |
137 | OXSR1 | 0.32400896 |
138 | FGFR3 | 0.32324167 |
139 | NEK6 | 0.32263130 |
140 | WNK1 | 0.32251964 |
141 | PKN1 | 0.32071388 |
142 | GRK6 | 0.31953060 |
143 | NUAK1 | 0.31859255 |
144 | MAPK4 | 0.31606924 |
145 | RPS6KB2 | 0.31563048 |
146 | PRKACG | 0.28575693 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Allograft rejection_Homo sapiens_hsa05330 | 3.55191793 |
2 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.80697175 |
3 | Ribosome_Homo sapiens_hsa03010 | 2.67686786 |
4 | Proteasome_Homo sapiens_hsa03050 | 2.64821805 |
5 | Asthma_Homo sapiens_hsa05310 | 2.63314406 |
6 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.59025334 |
7 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.58283261 |
8 | DNA replication_Homo sapiens_hsa03030 | 2.37662585 |
9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.16424349 |
10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.13823398 |
11 | RNA polymerase_Homo sapiens_hsa03020 | 2.07822607 |
12 | Leishmaniasis_Homo sapiens_hsa05140 | 2.06682499 |
13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.84517036 |
14 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.82838446 |
15 | Measles_Homo sapiens_hsa05162 | 1.80870368 |
16 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.76244837 |
17 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.72263814 |
18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.67885164 |
19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.67693261 |
20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.63566310 |
21 | Base excision repair_Homo sapiens_hsa03410 | 1.55853396 |
22 | Mismatch repair_Homo sapiens_hsa03430 | 1.55395225 |
23 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.51909336 |
24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.42481762 |
25 | Legionellosis_Homo sapiens_hsa05134 | 1.37283969 |
26 | Homologous recombination_Homo sapiens_hsa03440 | 1.32377308 |
27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.31052515 |
28 | Other glycan degradation_Homo sapiens_hsa00511 | 1.29140024 |
29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.27940527 |
30 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.27668496 |
31 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.25198954 |
32 | Malaria_Homo sapiens_hsa05144 | 1.21784113 |
33 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.19867674 |
34 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.18897698 |
35 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.15612520 |
36 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.11163502 |
37 | Pertussis_Homo sapiens_hsa05133 | 1.08612046 |
38 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.08305614 |
39 | Protein export_Homo sapiens_hsa03060 | 1.05121671 |
40 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.04342895 |
41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.03675367 |
42 | Spliceosome_Homo sapiens_hsa03040 | 1.03426822 |
43 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.01004221 |
44 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.98963435 |
45 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.97336308 |
46 | Influenza A_Homo sapiens_hsa05164 | 0.97040934 |
47 | Lysosome_Homo sapiens_hsa04142 | 0.96725690 |
48 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.96231810 |
49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.94971347 |
50 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92839614 |
51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.91100125 |
52 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.89513933 |
53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.89314411 |
54 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.88624521 |
55 | Apoptosis_Homo sapiens_hsa04210 | 0.87730100 |
56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.86445150 |
57 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.86311066 |
58 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.85622008 |
59 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.84770572 |
60 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.84123317 |
61 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.83009505 |
62 | Purine metabolism_Homo sapiens_hsa00230 | 0.82224468 |
63 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.81655547 |
64 | RNA degradation_Homo sapiens_hsa03018 | 0.79468515 |
65 | Phototransduction_Homo sapiens_hsa04744 | 0.78462778 |
66 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.77922671 |
67 | Shigellosis_Homo sapiens_hsa05131 | 0.77560409 |
68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.77098295 |
69 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.76772797 |
70 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.75315287 |
71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.75011978 |
72 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.72484639 |
73 | Tuberculosis_Homo sapiens_hsa05152 | 0.70630989 |
74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69542294 |
75 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.68635271 |
76 | ABC transporters_Homo sapiens_hsa02010 | 0.67709849 |
77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.67318949 |
78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.65667836 |
79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.64562599 |
80 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.64281401 |
81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.63019494 |
82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60633673 |
83 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.59306618 |
84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59231960 |
85 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57694026 |
86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.57623096 |
87 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.57112121 |
88 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56500337 |
89 | Peroxisome_Homo sapiens_hsa04146 | 0.56419387 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.56266203 |
91 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.56002936 |
92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.55911154 |
93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54764783 |
94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54619947 |
95 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.54144555 |
96 | Phagosome_Homo sapiens_hsa04145 | 0.53214299 |
97 | Hepatitis B_Homo sapiens_hsa05161 | 0.52395404 |
98 | RNA transport_Homo sapiens_hsa03013 | 0.51851004 |
99 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49829299 |
100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48942051 |
101 | Salmonella infection_Homo sapiens_hsa05132 | 0.48667912 |
102 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.48488296 |
103 | Parkinsons disease_Homo sapiens_hsa05012 | 0.48169474 |
104 | Mineral absorption_Homo sapiens_hsa04978 | 0.46902174 |
105 | Cell cycle_Homo sapiens_hsa04110 | 0.46821725 |
106 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.46620581 |
107 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.46095773 |
108 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.45869235 |
109 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44682440 |
110 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.44670877 |
111 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44404612 |
112 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44036137 |
113 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42140431 |
114 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.42040317 |
115 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.41904309 |
116 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.41455206 |
117 | Basal transcription factors_Homo sapiens_hsa03022 | 0.41293262 |
118 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41061315 |
119 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.40056284 |
120 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.39789833 |
121 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.39714566 |
122 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.39007957 |
123 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.38158944 |
124 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.37433878 |
125 | Hepatitis C_Homo sapiens_hsa05160 | 0.35090347 |
126 | Insulin resistance_Homo sapiens_hsa04931 | 0.34819035 |
127 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.32483475 |
128 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.32443217 |
129 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.32142468 |
130 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.30890887 |
131 | Alzheimers disease_Homo sapiens_hsa05010 | 0.29136035 |
132 | Platelet activation_Homo sapiens_hsa04611 | 0.27719649 |
133 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.26879600 |
134 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.22771599 |
135 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.20246287 |
136 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.18227410 |
137 | Retinol metabolism_Homo sapiens_hsa00830 | 0.17319543 |