Rank | Gene Set | Z-score |
---|---|---|
1 | neutrophil activation involved in immune response (GO:0002283) | 5.59283853 |
2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.43961130 |
3 | response to peptidoglycan (GO:0032494) | 5.00463345 |
4 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.79852079 |
5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.79852079 |
6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.79852079 |
7 | modulation by symbiont of host immune response (GO:0052553) | 4.79852079 |
8 | positive regulation by symbiont of host defense response (GO:0052509) | 4.79852079 |
9 | modulation by symbiont of host defense response (GO:0052031) | 4.79852079 |
10 | respiratory burst (GO:0045730) | 4.42025729 |
11 | immunoglobulin mediated immune response (GO:0016064) | 4.34046765 |
12 | pinocytosis (GO:0006907) | 4.20099676 |
13 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.19891558 |
14 | hydrogen peroxide biosynthetic process (GO:0050665) | 4.13671073 |
15 | reactive oxygen species biosynthetic process (GO:1903409) | 4.10721514 |
16 | positive regulation of interferon-alpha production (GO:0032727) | 4.08050385 |
17 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.02793907 |
18 | macrophage activation involved in immune response (GO:0002281) | 3.95028318 |
19 | granulocyte activation (GO:0036230) | 3.87248424 |
20 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.84852554 |
21 | regulation of interferon-alpha production (GO:0032647) | 3.84446963 |
22 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.76833573 |
23 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.76462701 |
24 | neutrophil activation (GO:0042119) | 3.73820052 |
25 | regulation of chemokine biosynthetic process (GO:0045073) | 3.69844820 |
26 | regulation of leukocyte degranulation (GO:0043300) | 3.67215959 |
27 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.65910590 |
28 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.62248805 |
29 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.61469628 |
30 | positive regulation of leukocyte degranulation (GO:0043302) | 3.61075483 |
31 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.51899299 |
32 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.51899299 |
33 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.49103960 |
34 | myeloid cell activation involved in immune response (GO:0002275) | 3.41004163 |
35 | leukocyte aggregation (GO:0070486) | 3.38615903 |
36 | glycosphingolipid catabolic process (GO:0046479) | 3.36613213 |
37 | defense response to protozoan (GO:0042832) | 3.33870135 |
38 | neutrophil mediated immunity (GO:0002446) | 3.33605184 |
39 | superoxide anion generation (GO:0042554) | 3.31059645 |
40 | response to interferon-beta (GO:0035456) | 3.31009229 |
41 | response to host immune response (GO:0052572) | 3.30719912 |
42 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.30719912 |
43 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.29663548 |
44 | response to interferon-alpha (GO:0035455) | 3.29477790 |
45 | B cell mediated immunity (GO:0019724) | 3.28273939 |
46 | response to thyroid hormone (GO:0097066) | 3.26814872 |
47 | type I interferon signaling pathway (GO:0060337) | 3.25658328 |
48 | cellular response to type I interferon (GO:0071357) | 3.25658328 |
49 | detection of molecule of bacterial origin (GO:0032490) | 3.25255590 |
50 | T-helper 1 type immune response (GO:0042088) | 3.24878811 |
51 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.22912092 |
52 | hyaluronan catabolic process (GO:0030214) | 3.22103736 |
53 | response to type I interferon (GO:0034340) | 3.22095108 |
54 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.22039884 |
55 | cellular extravasation (GO:0045123) | 3.21364082 |
56 | barbed-end actin filament capping (GO:0051016) | 3.20480527 |
57 | cellular response to interferon-beta (GO:0035458) | 3.17196870 |
58 | response to muramyl dipeptide (GO:0032495) | 3.16565528 |
59 | phagocytosis, engulfment (GO:0006911) | 3.15568915 |
60 | regulation of superoxide anion generation (GO:0032928) | 3.13858939 |
61 | cellular response to exogenous dsRNA (GO:0071360) | 3.13658464 |
62 | negative regulation of growth of symbiont in host (GO:0044130) | 3.13251128 |
63 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.13251128 |
64 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.13251128 |
65 | regulation of growth of symbiont in host (GO:0044126) | 3.13251128 |
66 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.08010707 |
67 | positive regulation of interferon-beta production (GO:0032728) | 3.06066523 |
68 | leukocyte mediated cytotoxicity (GO:0001909) | 3.00903697 |
69 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.00892358 |
70 | glycolipid catabolic process (GO:0019377) | 3.00532220 |
71 | response to protozoan (GO:0001562) | 2.99171130 |
72 | lipoxygenase pathway (GO:0019372) | 2.97878128 |
73 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.96947455 |
74 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.96064330 |
75 | response to host (GO:0075136) | 2.96064330 |
76 | response to host defenses (GO:0052200) | 2.96064330 |
77 | mature B cell differentiation involved in immune response (GO:0002313) | 2.95721929 |
78 | cellular response to zinc ion (GO:0071294) | 2.94776210 |
79 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.93180362 |
80 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 2.92846132 |
81 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 2.92846132 |
82 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.92490293 |
83 | positive regulation of mast cell degranulation (GO:0043306) | 2.92490293 |
84 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 2.91776089 |
85 | positive regulation of mast cell activation (GO:0033005) | 2.89363076 |
86 | macrophage activation (GO:0042116) | 2.89353003 |
87 | regulation of mast cell degranulation (GO:0043304) | 2.88463664 |
88 | regulation of mast cell activation (GO:0033003) | 2.87770660 |
89 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.86931444 |
90 | protein localization to endosome (GO:0036010) | 2.86696687 |
91 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.85885435 |
92 | adenosine receptor signaling pathway (GO:0001973) | 2.85746148 |
93 | positive regulation of antigen processing and presentation (GO:0002579) | 2.85576363 |
94 | natural killer cell mediated immunity (GO:0002228) | 2.84809920 |
95 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.84809920 |
96 | negative regulation of viral genome replication (GO:0045071) | 2.83992195 |
97 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.82282153 |
98 | positive regulation of B cell differentiation (GO:0045579) | 2.82057834 |
99 | detection of external biotic stimulus (GO:0098581) | 2.80323431 |
100 | membrane invagination (GO:0010324) | 2.79011849 |
101 | microglial cell activation (GO:0001774) | 2.77772214 |
102 | angiogenesis involved in wound healing (GO:0060055) | 2.77287917 |
103 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.76281239 |
104 | regulation of early endosome to late endosome transport (GO:2000641) | 2.76046575 |
105 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.75852264 |
106 | oligosaccharide catabolic process (GO:0009313) | 2.75777374 |
107 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.75615013 |
108 | regulation of regulated secretory pathway (GO:1903305) | 2.74602385 |
109 | detection of bacterium (GO:0016045) | 2.73163373 |
110 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.72868577 |
111 | positive regulation of heat generation (GO:0031652) | 2.72742957 |
112 | negative regulation of interleukin-17 production (GO:0032700) | 2.72110664 |
113 | myeloid leukocyte mediated immunity (GO:0002444) | 2.71801270 |
114 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.70909560 |
115 | response to fungus (GO:0009620) | 2.70734811 |
116 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.70315396 |
117 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.69568549 |
118 | regulation of RIG-I signaling pathway (GO:0039535) | 2.68705886 |
119 | amino sugar catabolic process (GO:0046348) | 2.68596592 |
120 | regulation of platelet activation (GO:0010543) | 2.68426110 |
121 | thrombin receptor signaling pathway (GO:0070493) | 2.68259618 |
122 | regulation of fever generation (GO:0031620) | 2.68135241 |
123 | platelet aggregation (GO:0070527) | 2.67748502 |
124 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.67511062 |
125 | NIK/NF-kappaB signaling (GO:0038061) | 2.67113869 |
126 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.66418678 |
127 | negative regulation of interleukin-12 production (GO:0032695) | 2.66378695 |
128 | positive regulation of tumor necrosis factor production (GO:0032760) | 2.65855859 |
129 | myeloid leukocyte activation (GO:0002274) | 2.65464102 |
130 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.64932387 |
131 | regulation of monocyte chemotaxis (GO:0090025) | 2.64455693 |
132 | detection of other organism (GO:0098543) | 2.64442904 |
133 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.64208013 |
134 | lymphocyte chemotaxis (GO:0048247) | 2.64049096 |
135 | regulation of platelet aggregation (GO:0090330) | 2.59855598 |
136 | cyclooxygenase pathway (GO:0019371) | 2.58691725 |
137 | stress fiber assembly (GO:0043149) | 2.55662036 |
138 | fibril organization (GO:0097435) | 2.55647336 |
139 | positive regulation of receptor recycling (GO:0001921) | 2.55621195 |
140 | positive regulation of regulated secretory pathway (GO:1903307) | 2.55542021 |
141 | ceramide catabolic process (GO:0046514) | 2.54977418 |
142 | cellular response to arsenic-containing substance (GO:0071243) | 2.53421297 |
143 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.53112864 |
144 | melanin biosynthetic process (GO:0042438) | 2.51568882 |
145 | detection of biotic stimulus (GO:0009595) | 2.49536267 |
146 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.46953836 |
147 | regulation of tumor necrosis factor superfamily cytokine production (GO:1903555) | 2.44176081 |
148 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.44064845 |
149 | leukocyte degranulation (GO:0043299) | 2.43886100 |
150 | extracellular fibril organization (GO:0043206) | 2.42989658 |
151 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.42938460 |
152 | hypotonic response (GO:0006971) | 2.38959125 |
153 | platelet degranulation (GO:0002576) | 2.38671587 |
154 | regulation of tumor necrosis factor production (GO:0032680) | 2.37336384 |
155 | regulation of superoxide metabolic process (GO:0090322) | 2.36676537 |
156 | regulation of T cell tolerance induction (GO:0002664) | 2.34354938 |
157 | regulation of tolerance induction (GO:0002643) | 2.34162027 |
158 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 2.30147545 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.00136132 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.95070933 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.34614480 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.86315792 |
5 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.79589350 |
6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.69066817 |
7 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.68839727 |
8 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.47583502 |
9 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.32634084 |
10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.28718789 |
11 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.12233352 |
12 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.04629588 |
13 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.70866866 |
14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.63973986 |
15 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.55814039 |
16 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.50305086 |
17 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.49675867 |
18 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.39252002 |
19 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.37044315 |
20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.30309779 |
21 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.29796797 |
22 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.25833048 |
23 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.23480709 |
24 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.22406380 |
25 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.12993042 |
26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.11456608 |
27 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.05476542 |
28 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.04600425 |
29 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.04574461 |
30 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.84030395 |
31 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.78679758 |
32 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.74939670 |
33 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.73492475 |
34 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.72619397 |
35 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.69978475 |
36 | GATA1_22025678_ChIP-Seq_K562_Human | 1.69280457 |
37 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.69248600 |
38 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.69008217 |
39 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68842543 |
40 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.67477626 |
41 | MYB_26560356_Chip-Seq_TH2_Human | 1.63805139 |
42 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.62258747 |
43 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.61242308 |
44 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.59214798 |
45 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.54957591 |
46 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.51125687 |
47 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.48934787 |
48 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.48744803 |
49 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46997764 |
50 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.43033907 |
51 | MAF_26560356_Chip-Seq_TH1_Human | 1.42058506 |
52 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.42044696 |
53 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.40554294 |
54 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.39960119 |
55 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.39606980 |
56 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.38275519 |
57 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37116276 |
58 | GATA1_19941826_ChIP-Seq_K562_Human | 1.36815736 |
59 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.34725400 |
60 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.34044497 |
61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.33584635 |
62 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.33496729 |
63 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.33086248 |
64 | MYB_26560356_Chip-Seq_TH1_Human | 1.32851838 |
65 | SPI1_23127762_ChIP-Seq_K562_Human | 1.30425067 |
66 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.29781711 |
67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29646834 |
68 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29527316 |
69 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.28816976 |
70 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.28738174 |
71 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.24771582 |
72 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.21756552 |
73 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.21360750 |
74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18631664 |
75 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.18600369 |
76 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.16707643 |
77 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16509291 |
78 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.13225902 |
79 | MYC_22102868_ChIP-Seq_BL_Human | 1.11556925 |
80 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.11264118 |
81 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.10883622 |
82 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.10545263 |
83 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.10403045 |
84 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10244870 |
85 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.10142777 |
86 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.09590385 |
87 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.08577390 |
88 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.06897508 |
89 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05820515 |
90 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04339826 |
91 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.03684406 |
92 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.03086314 |
93 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.02600289 |
94 | UTX_26944678_Chip-Seq_JUKART_Human | 1.01441764 |
95 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.01306651 |
96 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.01055748 |
97 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.00530208 |
98 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00189278 |
99 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.98871523 |
100 | * GATA2_19941826_ChIP-Seq_K562_Human | 0.98012846 |
101 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97701272 |
102 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.97580239 |
103 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.97465774 |
104 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.97037673 |
105 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.95723343 |
106 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.94693933 |
107 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.94130172 |
108 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.93930063 |
109 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.89783426 |
110 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.86587800 |
111 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.84685661 |
112 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.81508950 |
113 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.80395348 |
114 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.79238917 |
115 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.78687422 |
116 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.76897075 |
117 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.75283900 |
118 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.74000187 |
119 | MAF_26560356_Chip-Seq_TH2_Human | 0.73400339 |
120 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.73287282 |
121 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.72982724 |
122 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.72682135 |
123 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.71353576 |
124 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.71353576 |
125 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.69466978 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.13326545 |
2 | MP0009785_altered_susceptibility_to | 3.79251107 |
3 | MP0003436_decreased_susceptibility_to | 3.79056917 |
4 | MP0002148_abnormal_hypersensitivity_rea | 3.22731769 |
5 | MP0002419_abnormal_innate_immunity | 3.09131538 |
6 | MP0003724_increased_susceptibility_to | 2.88935449 |
7 | MP0005025_abnormal_response_to | 2.85407178 |
8 | MP0002877_abnormal_melanocyte_morpholog | 2.78703449 |
9 | MP0005000_abnormal_immune_tolerance | 2.75324318 |
10 | MP0006082_CNS_inflammation | 2.74399991 |
11 | MP0003303_peritoneal_inflammation | 2.69550503 |
12 | MP0000685_abnormal_immune_system | 2.54292592 |
13 | MP0005058_abnormal_lysosome_morphology | 2.49736520 |
14 | MP0001790_abnormal_immune_system | 2.36221692 |
15 | MP0005387_immune_system_phenotype | 2.36221692 |
16 | MP0005464_abnormal_platelet_physiology | 2.33165907 |
17 | MP0002452_abnormal_antigen_presenting | 2.32268330 |
18 | MP0002723_abnormal_immune_serum | 2.17071055 |
19 | MP0001800_abnormal_humoral_immune | 2.14030873 |
20 | MP0005671_abnormal_response_to | 2.12126387 |
21 | MP0004510_myositis | 2.09903810 |
22 | MP0009764_decreased_sensitivity_to | 2.07431068 |
23 | MP0001853_heart_inflammation | 2.05191668 |
24 | MP0000015_abnormal_ear_pigmentation | 2.02195082 |
25 | MP0001533_abnormal_skeleton_physiology | 1.97734513 |
26 | MP0001819_abnormal_immune_cell | 1.96643022 |
27 | MP0002420_abnormal_adaptive_immunity | 1.94021169 |
28 | MP0003191_abnormal_cellular_cholesterol | 1.93099263 |
29 | MP0009840_abnormal_foam_cell | 1.90385495 |
30 | MP0001845_abnormal_inflammatory_respons | 1.86636446 |
31 | MP0005171_absent_coat_pigmentation | 1.80685750 |
32 | MP0002006_tumorigenesis | 1.80155342 |
33 | MP0008469_abnormal_protein_level | 1.80016407 |
34 | MP0002139_abnormal_hepatobiliary_system | 1.77341427 |
35 | MP0003172_abnormal_lysosome_physiology | 1.73437330 |
36 | MP0003186_abnormal_redox_activity | 1.73078151 |
37 | MP0003075_altered_response_to | 1.69862017 |
38 | MP0000343_altered_response_to | 1.69611879 |
39 | MP0008260_abnormal_autophagy | 1.67382186 |
40 | MP0004947_skin_inflammation | 1.67374526 |
41 | MP0003279_aneurysm | 1.66078960 |
42 | MP0002405_respiratory_system_inflammati | 1.65895046 |
43 | MP0008004_abnormal_stomach_pH | 1.64933751 |
44 | MP0005360_urolithiasis | 1.64767928 |
45 | MP0000372_irregular_coat_pigmentation | 1.61838997 |
46 | MP0010155_abnormal_intestine_physiology | 1.59483845 |
47 | MP0005257_abnormal_intraocular_pressure | 1.58246862 |
48 | MP0002138_abnormal_hepatobiliary_system | 1.56611503 |
49 | MP0002166_altered_tumor_susceptibility | 1.46375336 |
50 | MP0001545_abnormal_hematopoietic_system | 1.46240242 |
51 | MP0005397_hematopoietic_system_phenotyp | 1.46240242 |
52 | MP0000858_altered_metastatic_potential | 1.45156978 |
53 | MP0003448_altered_tumor_morphology | 1.44277827 |
54 | MP0000716_abnormal_immune_system | 1.43049251 |
55 | MP0005408_hypopigmentation | 1.41062248 |
56 | MP0009333_abnormal_splenocyte_physiolog | 1.35590045 |
57 | MP0001542_abnormal_bone_strength | 1.32911713 |
58 | MP0009278_abnormal_bone_marrow | 1.31877580 |
59 | MP0002398_abnormal_bone_marrow | 1.30898070 |
60 | MP0001958_emphysema | 1.30488034 |
61 | MP0005075_abnormal_melanosome_morpholog | 1.29886640 |
62 | MP0003195_calcinosis | 1.28396511 |
63 | MP0005165_increased_susceptibility_to | 1.24764762 |
64 | MP0002998_abnormal_bone_remodeling | 1.24601581 |
65 | MP0005166_decreased_susceptibility_to | 1.24289532 |
66 | MP0009763_increased_sensitivity_to | 1.24230853 |
67 | MP0000689_abnormal_spleen_morphology | 1.18841317 |
68 | MP0002429_abnormal_blood_cell | 1.18720826 |
69 | MP0000604_amyloidosis | 1.16909195 |
70 | MP0004782_abnormal_surfactant_physiolog | 1.15708434 |
71 | MP0005365_abnormal_bile_salt | 1.15226306 |
72 | MP0005085_abnormal_gallbladder_physiolo | 1.15205234 |
73 | MP0005164_abnormal_response_to | 1.12781331 |
74 | MP0003091_abnormal_cell_migration | 1.11134169 |
75 | MP0002254_reproductive_system_inflammat | 1.09678110 |
76 | MP0003950_abnormal_plasma_membrane | 1.07153245 |
77 | MP0003806_abnormal_nucleotide_metabolis | 1.06705477 |
78 | MP0005083_abnormal_biliary_tract | 1.06571480 |
79 | MP0002722_abnormal_immune_system | 1.05727370 |
80 | MP0004272_abnormal_basement_membrane | 1.03319439 |
81 | MP0005174_abnormal_tail_pigmentation | 1.02845150 |
82 | MP0005167_abnormal_blood-brain_barrier | 1.02276590 |
83 | MP0002396_abnormal_hematopoietic_system | 1.01359161 |
84 | MP0003656_abnormal_erythrocyte_physiolo | 1.01289997 |
85 | MP0005319_abnormal_enzyme/_coenzyme | 0.98727276 |
86 | MP0005310_abnormal_salivary_gland | 0.97838147 |
87 | MP0003300_gastrointestinal_ulcer | 0.96648353 |
88 | MP0000609_abnormal_liver_physiology | 0.96199705 |
89 | MP0005390_skeleton_phenotype | 0.92953936 |
90 | MP0004883_abnormal_blood_vessel | 0.92395361 |
91 | MP0000465_gastrointestinal_hemorrhage | 0.91005457 |
92 | MP0003795_abnormal_bone_structure | 0.90305390 |
93 | MP0001849_ear_inflammation | 0.89123429 |
94 | MP0010329_abnormal_lipoprotein_level | 0.87456066 |
95 | MP0008875_abnormal_xenobiotic_pharmacok | 0.86304911 |
96 | MP0000249_abnormal_blood_vessel | 0.83656462 |
97 | MP0005409_darkened_coat_color | 0.83495267 |
98 | MP0008438_abnormal_cutaneous_collagen | 0.82870257 |
99 | MP0004808_abnormal_hematopoietic_stem | 0.82336023 |
100 | MP0009765_abnormal_xenobiotic_induced | 0.82170298 |
101 | MP0001851_eye_inflammation | 0.80606180 |
102 | MP0005275_abnormal_skin_tensile | 0.80314281 |
103 | MP0002095_abnormal_skin_pigmentation | 0.79961788 |
104 | MP0001663_abnormal_digestive_system | 0.79799047 |
105 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.79000604 |
106 | MP0003705_abnormal_hypodermis_morpholog | 0.77800668 |
107 | MP0003828_pulmonary_edema | 0.77670026 |
108 | MP0000490_abnormal_crypts_of | 0.77005724 |
109 | MP0000598_abnormal_liver_morphology | 0.76635762 |
110 | MP0001764_abnormal_homeostasis | 0.76520891 |
111 | MP0003252_abnormal_bile_duct | 0.76054553 |
112 | MP0010307_abnormal_tumor_latency | 0.75654729 |
113 | MP0001873_stomach_inflammation | 0.75396633 |
114 | MP0003183_abnormal_peptide_metabolism | 0.74738109 |
115 | MP0006054_spinal_hemorrhage | 0.74697759 |
116 | MP0003690_abnormal_glial_cell | 0.74459667 |
117 | MP0000371_diluted_coat_color | 0.74090654 |
118 | MP0005451_abnormal_body_composition | 0.73489647 |
119 | MP0004381_abnormal_hair_follicle | 0.73008138 |
120 | MP0010368_abnormal_lymphatic_system | 0.72724455 |
121 | MP0002933_joint_inflammation | 0.72063822 |
122 | MP0002132_abnormal_respiratory_system | 0.71621408 |
123 | MP0003566_abnormal_cell_adhesion | 0.71142799 |
124 | MP0003453_abnormal_keratinocyte_physiol | 0.71033213 |
125 | MP0005023_abnormal_wound_healing | 0.69132745 |
126 | MP0008873_increased_physiological_sensi | 0.68081726 |
127 | MP0003763_abnormal_thymus_physiology | 0.67977803 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 6.55314946 |
2 | Eczematoid dermatitis (HP:0000976) | 6.36065576 |
3 | Recurrent bacterial skin infections (HP:0005406) | 6.25585123 |
4 | Recurrent gram-negative bacterial infections (HP:0005420) | 6.20248407 |
5 | Abnormality of macrophages (HP:0004311) | 4.51974765 |
6 | Mediastinal lymphadenopathy (HP:0100721) | 4.49831719 |
7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.34926330 |
8 | Systemic lupus erythematosus (HP:0002725) | 4.24401332 |
9 | Recurrent skin infections (HP:0001581) | 4.02101319 |
10 | Myositis (HP:0100614) | 3.96341579 |
11 | Vacuolated lymphocytes (HP:0001922) | 3.91714373 |
12 | Autoimmune thrombocytopenia (HP:0001973) | 3.83683341 |
13 | Abnormal platelet volume (HP:0011876) | 3.72974625 |
14 | Increased mean platelet volume (HP:0011877) | 3.68722606 |
15 | Gingivitis (HP:0000230) | 3.60669562 |
16 | Orchitis (HP:0100796) | 3.45035007 |
17 | Chronic obstructive pulmonary disease (HP:0006510) | 3.37645822 |
18 | Obstructive lung disease (HP:0006536) | 3.37645822 |
19 | Recurrent fungal infections (HP:0002841) | 3.33033860 |
20 | Periodontitis (HP:0000704) | 3.31242811 |
21 | Joint hemorrhage (HP:0005261) | 3.16288663 |
22 | Loss of speech (HP:0002371) | 3.12713128 |
23 | Glomerulonephritis (HP:0000099) | 3.11562417 |
24 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.09958811 |
25 | Stomatitis (HP:0010280) | 3.07170435 |
26 | Increased cerebral lipofuscin (HP:0011813) | 3.05865339 |
27 | Vasculitis (HP:0002633) | 3.05138297 |
28 | Urticaria (HP:0001025) | 3.00903214 |
29 | Axonal loss (HP:0003447) | 2.99428312 |
30 | Recurrent viral infections (HP:0004429) | 2.93807175 |
31 | Gingival bleeding (HP:0000225) | 2.90797851 |
32 | Protrusio acetabuli (HP:0003179) | 2.89554744 |
33 | Premature rupture of membranes (HP:0001788) | 2.89055524 |
34 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.85262910 |
35 | Optic neuritis (HP:0100653) | 2.85231017 |
36 | Retrobulbar optic neuritis (HP:0100654) | 2.85231017 |
37 | Petechiae (HP:0000967) | 2.84273107 |
38 | Pustule (HP:0200039) | 2.81667540 |
39 | Cellulitis (HP:0100658) | 2.77857217 |
40 | Basal ganglia calcification (HP:0002135) | 2.73665818 |
41 | Prolonged partial thromboplastin time (HP:0003645) | 2.72271275 |
42 | Dysostosis multiplex (HP:0000943) | 2.70307843 |
43 | Thrombocytosis (HP:0001894) | 2.65660636 |
44 | Interstitial pulmonary disease (HP:0006530) | 2.58457056 |
45 | Myocardial infarction (HP:0001658) | 2.58243369 |
46 | Impaired platelet aggregation (HP:0003540) | 2.56370171 |
47 | Abnormal platelet function (HP:0011869) | 2.56370171 |
48 | Meningitis (HP:0001287) | 2.56245502 |
49 | Complement deficiency (HP:0004431) | 2.54783854 |
50 | Spondylolisthesis (HP:0003302) | 2.54408671 |
51 | Abnormality of complement system (HP:0005339) | 2.53190971 |
52 | Disinhibition (HP:0000734) | 2.52031146 |
53 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.46987989 |
54 | Recurrent cutaneous fungal infections (HP:0011370) | 2.46987989 |
55 | Chronic otitis media (HP:0000389) | 2.46583296 |
56 | Conjunctival telangiectasia (HP:0000524) | 2.46558783 |
57 | Epistaxis (HP:0000421) | 2.45177057 |
58 | Pulmonary infiltrates (HP:0002113) | 2.41775256 |
59 | Mucopolysacchariduria (HP:0008155) | 2.41605196 |
60 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.41605196 |
61 | Prostate neoplasm (HP:0100787) | 2.40860803 |
62 | Increased IgM level (HP:0003496) | 2.40015750 |
63 | Tetraparesis (HP:0002273) | 2.39411753 |
64 | Peritonitis (HP:0002586) | 2.38787073 |
65 | Nephritis (HP:0000123) | 2.34419234 |
66 | Abnormality of the prostate (HP:0008775) | 2.34417151 |
67 | Purpura (HP:0000979) | 2.34366166 |
68 | Reduced antithrombin III activity (HP:0001976) | 2.34353421 |
69 | Gastrointestinal infarctions (HP:0005244) | 2.34094836 |
70 | Upper motor neuron abnormality (HP:0002127) | 2.32775321 |
71 | Osteomyelitis (HP:0002754) | 2.28816593 |
72 | Recurrent pneumonia (HP:0006532) | 2.28093321 |
73 | Progressive neurologic deterioration (HP:0002344) | 2.26939374 |
74 | Hypergammaglobulinemia (HP:0010702) | 2.26063213 |
75 | Vertebral compression fractures (HP:0002953) | 2.25802409 |
76 | Increased serum ferritin (HP:0003281) | 2.25752100 |
77 | Prolonged neonatal jaundice (HP:0006579) | 2.25125805 |
78 | Arterial thrombosis (HP:0004420) | 2.24311056 |
79 | Abnormality of the common coagulation pathway (HP:0010990) | 2.23317207 |
80 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.22850176 |
81 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.22850176 |
82 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.22850176 |
83 | Spontaneous hematomas (HP:0007420) | 2.20151972 |
84 | Xanthomatosis (HP:0000991) | 2.18386514 |
85 | Hepatosplenomegaly (HP:0001433) | 2.17325198 |
86 | Leukocytosis (HP:0001974) | 2.17004255 |
87 | Poor head control (HP:0002421) | 2.16707362 |
88 | Osteolytic defects of the hand bones (HP:0009699) | 2.15195070 |
89 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.15195070 |
90 | Abnormality of iron homeostasis (HP:0011031) | 2.14346562 |
91 | Bruising susceptibility (HP:0000978) | 2.14097878 |
92 | Amyloidosis (HP:0011034) | 2.12174259 |
93 | Cervical subluxation (HP:0003308) | 2.11088515 |
94 | Deep venous thrombosis (HP:0002625) | 2.10532048 |
95 | Recurrent lower respiratory tract infections (HP:0002783) | 2.10406090 |
96 | Hemoptysis (HP:0002105) | 2.10323655 |
97 | Episodic fever (HP:0001954) | 2.10285151 |
98 | Prolonged bleeding time (HP:0003010) | 2.05132595 |
99 | Abnormality of T cell physiology (HP:0011840) | 2.04771421 |
100 | Abnormality of glycolipid metabolism (HP:0010969) | 2.04455572 |
101 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.04455572 |
102 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.04455572 |
103 | Hematochezia (HP:0002573) | 2.01831397 |
104 | Ocular albinism (HP:0001107) | 2.01741120 |
105 | Thick nail (HP:0001805) | 2.00420091 |
106 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.99659089 |
107 | Menorrhagia (HP:0000132) | 1.98914902 |
108 | Agnosia (HP:0010524) | 1.98330364 |
109 | Albinism (HP:0001022) | 1.96674839 |
110 | Gangrene (HP:0100758) | 1.96273874 |
111 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.95871155 |
112 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.95010112 |
113 | Keratoconjunctivitis sicca (HP:0001097) | 1.94772057 |
114 | Neoplasm of head and neck (HP:0012288) | 1.94344601 |
115 | Esophageal neoplasm (HP:0100751) | 1.94344601 |
116 | Pathologic fracture (HP:0002756) | 1.93370448 |
117 | Nuclear cataract (HP:0100018) | 1.93336613 |
118 | Asymmetric septal hypertrophy (HP:0001670) | 1.92119806 |
119 | Polycythemia (HP:0001901) | 1.92033842 |
120 | Thrombophlebitis (HP:0004418) | 1.90779827 |
121 | Joint stiffness (HP:0001387) | 1.87194497 |
122 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.86847194 |
123 | Hypertensive crisis (HP:0100735) | 1.86097598 |
124 | Chest pain (HP:0100749) | 1.84944182 |
125 | Mitral stenosis (HP:0001718) | 1.83037097 |
126 | Thoracic kyphosis (HP:0002942) | 1.76668460 |
127 | Mucosal telangiectasiae (HP:0100579) | 1.76277483 |
128 | White forelock (HP:0002211) | 1.75181054 |
129 | Abnormality of the Achilles tendon (HP:0005109) | 1.74532822 |
130 | Distal lower limb muscle weakness (HP:0009053) | 1.73582149 |
131 | Glomerulopathy (HP:0100820) | 1.73222250 |
132 | Aortic dissection (HP:0002647) | 1.73211494 |
133 | Hypertriglyceridemia (HP:0002155) | 1.71384512 |
134 | Bone pain (HP:0002653) | 1.70244383 |
135 | Blue sclerae (HP:0000592) | 1.69377570 |
136 | Hyperlipoproteinemia (HP:0010980) | 1.69266978 |
137 | Dilatation of the ascending aorta (HP:0005111) | 1.68709087 |
138 | Aortic aneurysm (HP:0004942) | 1.66043747 |
139 | Ovoid vertebral bodies (HP:0003300) | 1.63602187 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K14 | 4.10111540 |
2 | IRAK4 | 3.59700283 |
3 | RIPK4 | 3.40354301 |
4 | BLK | 3.38561462 |
5 | TBK1 | 3.21755365 |
6 | ERN1 | 2.80788750 |
7 | IRAK3 | 2.77365637 |
8 | TYK2 | 2.74525279 |
9 | KIT | 2.48796897 |
10 | PBK | 2.44157596 |
11 | IKBKE | 2.32083046 |
12 | JAK3 | 2.29181026 |
13 | TESK2 | 2.24445752 |
14 | PIM2 | 2.23190915 |
15 | IKBKB | 2.14386578 |
16 | MAP4K1 | 2.07337784 |
17 | MYLK | 1.85311356 |
18 | NEK9 | 1.81732496 |
19 | MAP3K13 | 1.78669221 |
20 | NME2 | 1.75209947 |
21 | TAOK3 | 1.69893010 |
22 | TXK | 1.64120046 |
23 | TEC | 1.58146434 |
24 | ZAP70 | 1.56764011 |
25 | JAK1 | 1.55426651 |
26 | SCYL2 | 1.54575041 |
27 | BTK | 1.49516670 |
28 | CSK | 1.44969630 |
29 | CSF1R | 1.44221982 |
30 | TGFBR2 | 1.43506590 |
31 | PRPF4B | 1.38506893 |
32 | FLT3 | 1.36574444 |
33 | CHUK | 1.35458210 |
34 | DDR2 | 1.35223049 |
35 | MATK | 1.35104930 |
36 | RPS6KA4 | 1.32204064 |
37 | SYK | 1.30897345 |
38 | ABL2 | 1.30084139 |
39 | MST1R | 1.29129128 |
40 | STK10 | 1.25503974 |
41 | TTN | 1.18901147 |
42 | LYN | 1.16486803 |
43 | MAP2K3 | 1.14855080 |
44 | PIM1 | 1.13372724 |
45 | TAOK1 | 1.11281183 |
46 | MAP3K1 | 1.07025957 |
47 | HCK | 1.05533364 |
48 | ILK | 0.98666035 |
49 | EIF2AK2 | 0.98076576 |
50 | TRPM7 | 0.97920783 |
51 | FGFR4 | 0.97426395 |
52 | JAK2 | 0.97398508 |
53 | EPHB1 | 0.93727229 |
54 | LCK | 0.93501528 |
55 | MAP3K6 | 0.91788447 |
56 | MAP3K12 | 0.91369333 |
57 | MAP3K5 | 0.89685763 |
58 | BMX | 0.89647708 |
59 | FES | 0.88348893 |
60 | DAPK3 | 0.84517085 |
61 | LRRK2 | 0.81296386 |
62 | LIMK1 | 0.80110307 |
63 | MAP3K11 | 0.79618975 |
64 | EPHB2 | 0.79371490 |
65 | STK4 | 0.78370372 |
66 | PRKD2 | 0.77081733 |
67 | PTK2B | 0.75252891 |
68 | PDPK1 | 0.74651434 |
69 | PAK1 | 0.72610145 |
70 | PAK2 | 0.72183242 |
71 | FGR | 0.71897575 |
72 | TNK2 | 0.71644146 |
73 | KDR | 0.71143179 |
74 | MST4 | 0.69216901 |
75 | ARAF | 0.68723577 |
76 | MOS | 0.67719242 |
77 | BMPR2 | 0.66795530 |
78 | ACVR1B | 0.66145896 |
79 | PRKCD | 0.65897864 |
80 | EIF2AK3 | 0.65820966 |
81 | CLK1 | 0.65653849 |
82 | IRAK1 | 0.65006819 |
83 | PDK2 | 0.63243408 |
84 | GRK5 | 0.62101742 |
85 | PKN2 | 0.59787811 |
86 | CDC42BPA | 0.59576950 |
87 | TESK1 | 0.59451233 |
88 | NLK | 0.57655426 |
89 | MARK3 | 0.57642492 |
90 | PTK2 | 0.57579284 |
91 | BCKDK | 0.57301220 |
92 | PAK4 | 0.56548641 |
93 | PDGFRA | 0.56240925 |
94 | MAP3K10 | 0.56061488 |
95 | ABL1 | 0.56051029 |
96 | TGFBR1 | 0.55470329 |
97 | GSK3A | 0.53422836 |
98 | MAP3K3 | 0.52920923 |
99 | RIPK1 | 0.51892820 |
100 | PIK3CG | 0.50962099 |
101 | IRAK2 | 0.50014064 |
102 | TAOK2 | 0.49215543 |
103 | FGFR3 | 0.48538442 |
104 | PDK1 | 0.48500197 |
105 | EGFR | 0.47993366 |
106 | BMPR1B | 0.47774366 |
107 | ITK | 0.46652106 |
108 | ADRBK1 | 0.45049659 |
109 | RPS6KA2 | 0.44349853 |
110 | PRKG2 | 0.44026205 |
111 | ERBB4 | 0.43599813 |
112 | SIK1 | 0.42690826 |
113 | STK3 | 0.42320627 |
114 | SIK3 | 0.42156777 |
115 | RPS6KL1 | 0.42142475 |
116 | RPS6KC1 | 0.42142475 |
117 | MAPK11 | 0.40073918 |
118 | ERBB3 | 0.40039877 |
119 | YES1 | 0.39866531 |
120 | PTK6 | 0.39321602 |
121 | CDK6 | 0.39160486 |
122 | EIF2AK1 | 0.37941331 |
123 | MAP3K8 | 0.37758974 |
124 | CAMKK2 | 0.36135725 |
125 | TRIB3 | 0.36122210 |
126 | RPS6KA6 | 0.35509510 |
127 | CDK4 | 0.35437020 |
128 | GRK7 | 0.35346258 |
129 | GRK6 | 0.35127145 |
130 | MAPKAPK2 | 0.34542689 |
131 | MAPK4 | 0.33492664 |
132 | EPHA3 | 0.33405166 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.75509403 |
2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.34746294 |
3 | Legionellosis_Homo sapiens_hsa05134 | 2.69613046 |
4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.57558536 |
5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.56164430 |
6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.44937911 |
7 | Pertussis_Homo sapiens_hsa05133 | 2.40832963 |
8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.32639168 |
9 | Malaria_Homo sapiens_hsa05144 | 2.20630578 |
10 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.13390220 |
11 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.12893093 |
12 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.04512955 |
13 | Tuberculosis_Homo sapiens_hsa05152 | 1.94919485 |
14 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.90555062 |
15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.87522355 |
16 | Allograft rejection_Homo sapiens_hsa05330 | 1.86357524 |
17 | Measles_Homo sapiens_hsa05162 | 1.82954563 |
18 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.76900154 |
19 | Lysosome_Homo sapiens_hsa04142 | 1.67643429 |
20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.66825622 |
21 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.63239006 |
22 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.63171149 |
23 | Asthma_Homo sapiens_hsa05310 | 1.62894019 |
24 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.59334047 |
25 | Influenza A_Homo sapiens_hsa05164 | 1.58020504 |
26 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.56938836 |
27 | Other glycan degradation_Homo sapiens_hsa00511 | 1.56879445 |
28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.54418788 |
29 | Salmonella infection_Homo sapiens_hsa05132 | 1.52895660 |
30 | Phagosome_Homo sapiens_hsa04145 | 1.48526091 |
31 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.43810250 |
32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.42957592 |
33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.40335217 |
34 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.36922205 |
35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.32095080 |
36 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.31730005 |
37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.30727829 |
38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.27652707 |
39 | Galactose metabolism_Homo sapiens_hsa00052 | 1.26245340 |
40 | Bladder cancer_Homo sapiens_hsa05219 | 1.25998966 |
41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.19760483 |
42 | Shigellosis_Homo sapiens_hsa05131 | 1.18872011 |
43 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.18477674 |
44 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.18238512 |
45 | Apoptosis_Homo sapiens_hsa04210 | 1.16393218 |
46 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.14754380 |
47 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.11118390 |
48 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.10175917 |
49 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.01319323 |
50 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.00546127 |
51 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.99182397 |
52 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.98345733 |
53 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.94779678 |
54 | Histidine metabolism_Homo sapiens_hsa00340 | 0.93923198 |
55 | Peroxisome_Homo sapiens_hsa04146 | 0.93478188 |
56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.89497604 |
57 | Endocytosis_Homo sapiens_hsa04144 | 0.84012996 |
58 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.84008457 |
59 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.83192559 |
60 | Hepatitis B_Homo sapiens_hsa05161 | 0.82871060 |
61 | Amoebiasis_Homo sapiens_hsa05146 | 0.80579476 |
62 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.79491739 |
63 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.77627973 |
64 | Hepatitis C_Homo sapiens_hsa05160 | 0.77538012 |
65 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.75502142 |
66 | Focal adhesion_Homo sapiens_hsa04510 | 0.75415172 |
67 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.75402476 |
68 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.74452247 |
69 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.74174656 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.72942285 |
71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.72273922 |
72 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.69419180 |
73 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.69384011 |
74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.67860251 |
75 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67337310 |
76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.66351622 |
77 | Prion diseases_Homo sapiens_hsa05020 | 0.65417550 |
78 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.64586614 |
79 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.62839286 |
80 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.62545035 |
81 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.62218705 |
82 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.62025426 |
83 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61900182 |
84 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.60966715 |
85 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.59277638 |
86 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56053467 |
87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55493632 |
88 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.54246253 |
89 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.53296367 |
90 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.52612305 |
91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52530540 |
92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52006079 |
93 | ABC transporters_Homo sapiens_hsa02010 | 0.50714709 |
94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.50627054 |
95 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.50482327 |
96 | Platelet activation_Homo sapiens_hsa04611 | 0.49733166 |
97 | Proteasome_Homo sapiens_hsa03050 | 0.49405742 |
98 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.49266311 |
99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47854452 |
100 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46744818 |
101 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.45690402 |
102 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45297099 |
103 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44666250 |
104 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44522458 |
105 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.43867136 |
106 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.41599218 |
107 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41243215 |
108 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41241726 |
109 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.41115225 |
110 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.40228235 |
111 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.36570616 |
112 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.36472516 |
113 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.35031032 |
114 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34106812 |
115 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.33332281 |
116 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.32631558 |
117 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31979159 |
118 | HTLV-I infection_Homo sapiens_hsa05166 | 0.31949638 |
119 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.31430237 |
120 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.30890295 |
121 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.30248581 |
122 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.30021137 |
123 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.27656132 |
124 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.27607380 |
125 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.26862599 |
126 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.25965691 |
127 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.25209942 |