Rank | Gene Set | Z-score |
---|---|---|
1 | central nervous system myelination (GO:0022010) | 9.19849806 |
2 | axon ensheathment in central nervous system (GO:0032291) | 9.19849806 |
3 | fatty acid elongation (GO:0030497) | 6.80398890 |
4 | myelination (GO:0042552) | 5.97601050 |
5 | axon ensheathment (GO:0008366) | 5.96022708 |
6 | ensheathment of neurons (GO:0007272) | 5.96022708 |
7 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.70114995 |
8 | long-chain fatty acid biosynthetic process (GO:0042759) | 5.65692541 |
9 | presynaptic membrane assembly (GO:0097105) | 4.77144496 |
10 | presynaptic membrane organization (GO:0097090) | 4.73996421 |
11 | neuron cell-cell adhesion (GO:0007158) | 4.59225354 |
12 | sequestering of actin monomers (GO:0042989) | 4.53447561 |
13 | negative regulation of neurotransmitter secretion (GO:0046929) | 4.47124946 |
14 | regulation of collateral sprouting (GO:0048670) | 4.44566781 |
15 | cholesterol biosynthetic process (GO:0006695) | 4.40610471 |
16 | nucleobase catabolic process (GO:0046113) | 4.33747407 |
17 | gamma-aminobutyric acid transport (GO:0015812) | 4.33449895 |
18 | substantia nigra development (GO:0021762) | 4.28575820 |
19 | negative regulation of neurotransmitter transport (GO:0051589) | 4.26211738 |
20 | establishment of mitochondrion localization (GO:0051654) | 4.23767075 |
21 | oligodendrocyte differentiation (GO:0048709) | 4.14472620 |
22 | synaptic vesicle maturation (GO:0016188) | 4.06454781 |
23 | apical protein localization (GO:0045176) | 4.04617932 |
24 | neurofilament cytoskeleton organization (GO:0060052) | 4.00006731 |
25 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.93064636 |
26 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.90754617 |
27 | glycerophospholipid catabolic process (GO:0046475) | 3.85638563 |
28 | sterol biosynthetic process (GO:0016126) | 3.81642316 |
29 | positive regulation of amino acid transport (GO:0051957) | 3.76466144 |
30 | response to redox state (GO:0051775) | 3.73496014 |
31 | transmission of nerve impulse (GO:0019226) | 3.71118283 |
32 | asymmetric protein localization (GO:0008105) | 3.64755375 |
33 | negative regulation of axonogenesis (GO:0050771) | 3.60721031 |
34 | postsynaptic membrane organization (GO:0001941) | 3.57292855 |
35 | negative regulation of protein localization to cell surface (GO:2000009) | 3.56484825 |
36 | isoprenoid biosynthetic process (GO:0008299) | 3.53829409 |
37 | photoreceptor cell differentiation (GO:0046530) | 3.52317763 |
38 | eye photoreceptor cell differentiation (GO:0001754) | 3.52317763 |
39 | cerebellar granule cell differentiation (GO:0021707) | 3.50361757 |
40 | myelin maintenance (GO:0043217) | 3.46406091 |
41 | creatine metabolic process (GO:0006600) | 3.42961373 |
42 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.41318957 |
43 | astrocyte development (GO:0014002) | 3.39719269 |
44 | cellular response to epinephrine stimulus (GO:0071872) | 3.36144543 |
45 | glutamate receptor signaling pathway (GO:0007215) | 3.34287454 |
46 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 3.30869140 |
47 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.26865596 |
48 | chaperone-mediated protein transport (GO:0072321) | 3.24037132 |
49 | adult walking behavior (GO:0007628) | 3.23998201 |
50 | regulation of synaptic vesicle transport (GO:1902803) | 3.23610074 |
51 | neuronal action potential propagation (GO:0019227) | 3.22658208 |
52 | regulation of glutamate secretion (GO:0014048) | 3.22395417 |
53 | negative regulation of axon extension (GO:0030517) | 3.21556176 |
54 | limb bud formation (GO:0060174) | 3.21391803 |
55 | L-amino acid import (GO:0043092) | 3.21064197 |
56 | neuron recognition (GO:0008038) | 3.21055779 |
57 | adhesion of symbiont to host cell (GO:0044650) | 3.19565951 |
58 | virion attachment to host cell (GO:0019062) | 3.19565951 |
59 | behavioral response to nicotine (GO:0035095) | 3.16393087 |
60 | response to epinephrine (GO:0071871) | 3.15829230 |
61 | positive regulation of action potential (GO:0045760) | 3.14786846 |
62 | long-chain fatty-acyl-CoA metabolic process (GO:0035336) | 3.14552966 |
63 | neuronal ion channel clustering (GO:0045161) | 3.13735935 |
64 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.13207174 |
65 | protein complex biogenesis (GO:0070271) | 3.10659581 |
66 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.10594881 |
67 | glutamate secretion (GO:0014047) | 3.09991414 |
68 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.06849521 |
69 | mitochondrion transport along microtubule (GO:0047497) | 3.06849521 |
70 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.03630311 |
71 | peripheral nervous system axon ensheathment (GO:0032292) | 3.02740703 |
72 | myelination in peripheral nervous system (GO:0022011) | 3.02740703 |
73 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.02048094 |
74 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.02048094 |
75 | regulation of synapse structural plasticity (GO:0051823) | 3.01959395 |
76 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.01060972 |
77 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.00519145 |
78 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.99820731 |
79 | neural nucleus development (GO:0048857) | 2.96860932 |
80 | protein localization to synapse (GO:0035418) | 2.94998170 |
81 | vocalization behavior (GO:0071625) | 2.94317724 |
82 | response to hepatocyte growth factor (GO:0035728) | 2.93863853 |
83 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 2.93863853 |
84 | response to methylmercury (GO:0051597) | 2.93012569 |
85 | neurotransmitter secretion (GO:0007269) | 2.92952453 |
86 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.91534606 |
87 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.91456205 |
88 | NADH dehydrogenase complex assembly (GO:0010257) | 2.91456205 |
89 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.91456205 |
90 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.87292215 |
91 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.87173130 |
92 | negative regulation of microtubule polymerization (GO:0031115) | 2.86982909 |
93 | negative regulation of telomere maintenance (GO:0032205) | 2.86760900 |
94 | short-term memory (GO:0007614) | 2.85685899 |
95 | synaptic vesicle exocytosis (GO:0016079) | 2.83432933 |
96 | negative regulation of heart rate (GO:0010459) | 2.83129968 |
97 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.82782643 |
98 | protein insertion into membrane (GO:0051205) | 2.82015045 |
99 | protein neddylation (GO:0045116) | 2.81609346 |
100 | protein palmitoylation (GO:0018345) | 2.81261454 |
101 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 2.79817149 |
102 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.79812468 |
103 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.79482953 |
104 | neuron remodeling (GO:0016322) | 2.78953748 |
105 | response to auditory stimulus (GO:0010996) | 2.77751557 |
106 | DNA deamination (GO:0045006) | 2.77519994 |
107 | exploration behavior (GO:0035640) | 2.75964036 |
108 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.75853288 |
109 | peripheral nervous system development (GO:0007422) | 2.74961630 |
110 | membrane assembly (GO:0071709) | 2.74835044 |
111 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.74550721 |
112 | peptidyl-cysteine modification (GO:0018198) | 2.72885156 |
113 | axonal fasciculation (GO:0007413) | 2.72745715 |
114 | regulation of neurotransmitter secretion (GO:0046928) | 2.70824840 |
115 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.69493091 |
116 | auditory behavior (GO:0031223) | 2.69064499 |
117 | positive regulation of mitochondrial fission (GO:0090141) | 2.68673800 |
118 | protein localization to cilium (GO:0061512) | 2.68533138 |
119 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.68262420 |
120 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.68262420 |
121 | dendritic spine morphogenesis (GO:0060997) | 2.67841040 |
122 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.67102055 |
123 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.66506236 |
124 | regulation of amino acid transport (GO:0051955) | 2.65804614 |
125 | synapse assembly (GO:0007416) | 2.64799312 |
126 | GPI anchor biosynthetic process (GO:0006506) | 2.64110450 |
127 | cellular response to monoamine stimulus (GO:0071868) | 2.63534849 |
128 | cellular response to catecholamine stimulus (GO:0071870) | 2.63534849 |
129 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.62465584 |
130 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.61477358 |
131 | regulation of catecholamine metabolic process (GO:0042069) | 2.61435080 |
132 | regulation of dopamine metabolic process (GO:0042053) | 2.61435080 |
133 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.61292566 |
134 | GPI anchor metabolic process (GO:0006505) | 2.61072924 |
135 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.61066908 |
136 | ATP synthesis coupled proton transport (GO:0015986) | 2.61066908 |
137 | dendrite morphogenesis (GO:0048813) | 2.60150498 |
138 | fatty-acyl-CoA metabolic process (GO:0035337) | 2.60122909 |
139 | dendrite development (GO:0016358) | 2.59725205 |
140 | axon development (GO:0061564) | 2.59418623 |
141 | activated T cell proliferation (GO:0050798) | 2.58810629 |
142 | amyloid precursor protein metabolic process (GO:0042982) | 2.58717573 |
143 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.58695742 |
144 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.58313692 |
145 | cell migration in hindbrain (GO:0021535) | 2.58121179 |
146 | regulation of feeding behavior (GO:0060259) | 2.57677509 |
147 | iron-sulfur cluster assembly (GO:0016226) | 2.56073898 |
148 | metallo-sulfur cluster assembly (GO:0031163) | 2.56073898 |
149 | neuron-neuron synaptic transmission (GO:0007270) | 2.55957810 |
150 | synaptic transmission, glutamatergic (GO:0035249) | 2.55470992 |
151 | synaptic transmission, cholinergic (GO:0007271) | 2.55323349 |
152 | negative regulation of mast cell activation (GO:0033004) | 2.55312301 |
153 | membrane tubulation (GO:0097320) | 2.55035635 |
154 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.54972437 |
155 | positive regulation of synapse assembly (GO:0051965) | 2.54741413 |
156 | regulation of action potential (GO:0098900) | 2.54565621 |
157 | regulation of vesicle fusion (GO:0031338) | 2.54493545 |
158 | negative regulation of amino acid transport (GO:0051956) | 2.53448588 |
159 | response to catecholamine (GO:0071869) | 2.52735599 |
160 | response to monoamine (GO:0071867) | 2.52735599 |
161 | positive regulation of amine transport (GO:0051954) | 2.51376619 |
162 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.50096964 |
163 | response to pheromone (GO:0019236) | 2.49978130 |
164 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.49560956 |
165 | negative regulation of cation channel activity (GO:2001258) | 2.49100168 |
166 | positive regulation of protein homodimerization activity (GO:0090073) | 2.48708543 |
167 | glycosphingolipid biosynthetic process (GO:0006688) | 2.47255993 |
168 | negative regulation of synaptic transmission (GO:0050805) | 2.46952553 |
169 | actin nucleation (GO:0045010) | 2.46358903 |
170 | neuromuscular synaptic transmission (GO:0007274) | 2.46163375 |
171 | regulation of neurotransmitter transport (GO:0051588) | 2.46117288 |
172 | behavioral response to ethanol (GO:0048149) | 2.46052413 |
173 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.46011830 |
174 | regulation of neurotransmitter levels (GO:0001505) | 2.45085210 |
175 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 2.44687542 |
176 | synaptic transmission, dopaminergic (GO:0001963) | 2.44522694 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.99971378 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.72361037 |
3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.80039340 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.79093033 |
5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.77358208 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.71603412 |
7 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.67034724 |
8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.49452824 |
9 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 2.40658010 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.32943364 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.32943364 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.27678587 |
13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.27152084 |
14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.21030838 |
15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.19439737 |
16 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.17596371 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.16317957 |
18 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.15053800 |
19 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.14260117 |
20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.12968526 |
21 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.08931134 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.05405560 |
23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.04981654 |
24 | VDR_22108803_ChIP-Seq_LS180_Human | 2.04800008 |
25 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.04273662 |
26 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.03641677 |
27 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.92609878 |
28 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.91447096 |
29 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.89392545 |
30 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.86610196 |
31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.82012532 |
32 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.80270281 |
33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73366980 |
34 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.72913453 |
35 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.72847560 |
36 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.72701861 |
37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.71128359 |
38 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.70210816 |
39 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.69106979 |
40 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.67976851 |
41 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.66926478 |
42 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.62958928 |
43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.62820739 |
44 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.60526458 |
45 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.59350945 |
46 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.58861286 |
47 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.57127521 |
48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.56530728 |
49 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.56238584 |
50 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.55955262 |
51 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.54343519 |
52 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53074515 |
53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.52838215 |
54 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.48501528 |
55 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.48427713 |
56 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.45218777 |
57 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.44537730 |
58 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.42900568 |
59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.42160528 |
60 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.39932868 |
61 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.39626082 |
62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.36096102 |
63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.34813631 |
64 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.34702152 |
65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.31012394 |
66 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.30456243 |
67 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.29173534 |
68 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26914410 |
69 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.24165061 |
70 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.23477583 |
71 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21871987 |
72 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.16908469 |
73 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.15806199 |
74 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15631169 |
75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.14165781 |
76 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.12813009 |
77 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11417749 |
78 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.10396422 |
79 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.08781536 |
80 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.07395948 |
81 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.07299184 |
82 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.06946518 |
83 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.06550370 |
84 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.06263064 |
85 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.06047942 |
86 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.05065685 |
87 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.04255754 |
88 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.03749269 |
89 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.03277757 |
90 | TCF4_23295773_ChIP-Seq_U87_Human | 1.02696545 |
91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02432113 |
92 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.01908250 |
93 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.01851576 |
94 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01825568 |
95 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.01324288 |
96 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.01110519 |
97 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.01053893 |
98 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.00627449 |
99 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.00222394 |
100 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.00185000 |
101 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.99100739 |
102 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.99010625 |
103 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.98857468 |
104 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.98681949 |
105 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98385112 |
106 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98385112 |
107 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.98335302 |
108 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98249350 |
109 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.98232621 |
110 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.97507395 |
111 | JUN_21703547_ChIP-Seq_K562_Human | 0.97191404 |
112 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.96618829 |
113 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.96438829 |
114 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.96004657 |
115 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.95018009 |
116 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.94868748 |
117 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94421463 |
118 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.93603187 |
119 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.93452262 |
120 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.93378195 |
121 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.93361179 |
122 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.93249931 |
123 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92568854 |
124 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92463258 |
125 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92463258 |
126 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91881982 |
127 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.91082520 |
128 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.91002262 |
129 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.90842196 |
130 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.90817355 |
131 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.90081593 |
132 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90076006 |
133 | AR_25329375_ChIP-Seq_VCAP_Human | 0.89844922 |
134 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89467974 |
135 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.89374260 |
136 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.88471333 |
137 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.87225383 |
138 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.86910753 |
139 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.84582957 |
140 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.84524708 |
141 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.83055616 |
142 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.80464432 |
143 | * MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.80458753 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.08311309 |
2 | MP0000920_abnormal_myelination | 4.19132728 |
3 | MP0004270_analgesia | 3.69746510 |
4 | MP0004859_abnormal_synaptic_plasticity | 3.30937909 |
5 | MP0001529_abnormal_vocalization | 2.98146010 |
6 | MP0002272_abnormal_nervous_system | 2.73637908 |
7 | MP0002064_seizures | 2.62797586 |
8 | MP0001486_abnormal_startle_reflex | 2.58738553 |
9 | MP0001905_abnormal_dopamine_level | 2.57337936 |
10 | MP0000778_abnormal_nervous_system | 2.55910403 |
11 | MP0003635_abnormal_synaptic_transmissio | 2.54208025 |
12 | MP0009745_abnormal_behavioral_response | 2.36452230 |
13 | MP0004742_abnormal_vestibular_system | 2.35915086 |
14 | MP0002638_abnormal_pupillary_reflex | 2.35602655 |
15 | MP0003950_abnormal_plasma_membrane | 2.32357892 |
16 | MP0009046_muscle_twitch | 2.32258273 |
17 | MP0003329_amyloid_beta_deposits | 2.26133593 |
18 | MP0002734_abnormal_mechanical_nocicepti | 2.23724713 |
19 | MP0004885_abnormal_endolymph | 2.22492418 |
20 | MP0003690_abnormal_glial_cell | 2.20343525 |
21 | MP0005171_absent_coat_pigmentation | 2.19842344 |
22 | MP0004142_abnormal_muscle_tone | 2.10132981 |
23 | MP0003136_yellow_coat_color | 2.10113479 |
24 | MP0001485_abnormal_pinna_reflex | 2.05495708 |
25 | MP0002572_abnormal_emotion/affect_behav | 2.05118193 |
26 | MP0005423_abnormal_somatic_nervous | 2.03502961 |
27 | MP0002063_abnormal_learning/memory/cond | 2.03131384 |
28 | MP0001968_abnormal_touch/_nociception | 1.94321493 |
29 | MP0003634_abnormal_glial_cell | 1.90652018 |
30 | MP0001440_abnormal_grooming_behavior | 1.90617641 |
31 | MP0005409_darkened_coat_color | 1.87589633 |
32 | MP0005671_abnormal_response_to | 1.81755016 |
33 | MP0002735_abnormal_chemical_nociception | 1.77277451 |
34 | MP0005499_abnormal_olfactory_system | 1.69870419 |
35 | MP0005394_taste/olfaction_phenotype | 1.69870419 |
36 | MP0002229_neurodegeneration | 1.69521955 |
37 | MP0002067_abnormal_sensory_capabilities | 1.63303026 |
38 | MP0002882_abnormal_neuron_morphology | 1.59383958 |
39 | MP0002736_abnormal_nociception_after | 1.59368876 |
40 | MP0000955_abnormal_spinal_cord | 1.58487882 |
41 | MP0001970_abnormal_pain_threshold | 1.56507492 |
42 | MP0004924_abnormal_behavior | 1.53175380 |
43 | MP0005386_behavior/neurological_phenoty | 1.53175380 |
44 | MP0003632_abnormal_nervous_system | 1.52738250 |
45 | MP0002733_abnormal_thermal_nociception | 1.49623643 |
46 | MP0000462_abnormal_digestive_system | 1.48065953 |
47 | MP0005451_abnormal_body_composition | 1.41520343 |
48 | MP0002066_abnormal_motor_capabilities/c | 1.40324813 |
49 | MP0005410_abnormal_fertilization | 1.38999270 |
50 | MP0002184_abnormal_innervation | 1.38010955 |
51 | MP0005551_abnormal_eye_electrophysiolog | 1.36028348 |
52 | MP0008877_abnormal_DNA_methylation | 1.34541544 |
53 | MP0006276_abnormal_autonomic_nervous | 1.33787707 |
54 | MP0003121_genomic_imprinting | 1.32060902 |
55 | MP0001963_abnormal_hearing_physiology | 1.31550482 |
56 | MP0002752_abnormal_somatic_nervous | 1.29673916 |
57 | MP0008569_lethality_at_weaning | 1.27081455 |
58 | MP0005084_abnormal_gallbladder_morpholo | 1.26708725 |
59 | MP0003938_abnormal_ear_development | 1.26165702 |
60 | MP0001986_abnormal_taste_sensitivity | 1.25998353 |
61 | MP0003303_peritoneal_inflammation | 1.25753720 |
62 | MP0004134_abnormal_chest_morphology | 1.24203169 |
63 | MP0006035_abnormal_mitochondrial_morpho | 1.21395607 |
64 | MP0002653_abnormal_ependyma_morphology | 1.20337416 |
65 | MP0010386_abnormal_urinary_bladder | 1.20174564 |
66 | MP0001984_abnormal_olfaction | 1.16903248 |
67 | MP0008789_abnormal_olfactory_epithelium | 1.15917548 |
68 | MP0003631_nervous_system_phenotype | 1.14637435 |
69 | MP0002557_abnormal_social/conspecific_i | 1.10161943 |
70 | MP0002152_abnormal_brain_morphology | 1.06699510 |
71 | MP0003787_abnormal_imprinting | 1.02922447 |
72 | MP0000026_abnormal_inner_ear | 1.01553365 |
73 | MP0001501_abnormal_sleep_pattern | 1.00456097 |
74 | MP0000604_amyloidosis | 0.99268360 |
75 | MP0004145_abnormal_muscle_electrophysio | 0.98596325 |
76 | MP0004811_abnormal_neuron_physiology | 0.97436470 |
77 | MP0008872_abnormal_physiological_respon | 0.96348615 |
78 | MP0005535_abnormal_body_temperature | 0.94068161 |
79 | MP0003633_abnormal_nervous_system | 0.92034147 |
80 | MP0005195_abnormal_posterior_eye | 0.91561639 |
81 | MP0004147_increased_porphyrin_level | 0.89940117 |
82 | MP0004381_abnormal_hair_follicle | 0.88956445 |
83 | MP0004043_abnormal_pH_regulation | 0.87442543 |
84 | MP0008874_decreased_physiological_sensi | 0.86693275 |
85 | MP0001790_abnormal_immune_system | 0.85840006 |
86 | MP0005387_immune_system_phenotype | 0.85840006 |
87 | MP0005623_abnormal_meninges_morphology | 0.85644934 |
88 | MP0003724_increased_susceptibility_to | 0.85558345 |
89 | MP0000631_abnormal_neuroendocrine_gland | 0.84864173 |
90 | MP0009764_decreased_sensitivity_to | 0.84323838 |
91 | MP0003122_maternal_imprinting | 0.83199702 |
92 | MP0002069_abnormal_eating/drinking_beha | 0.82761255 |
93 | MP0005645_abnormal_hypothalamus_physiol | 0.82483190 |
94 | MP0001835_abnormal_antigen_presentation | 0.81655684 |
95 | MP0001299_abnormal_eye_distance/ | 0.81371104 |
96 | MP0002822_catalepsy | 0.80934698 |
97 | MP0002277_abnormal_respiratory_mucosa | 0.80809842 |
98 | MP0005000_abnormal_immune_tolerance | 0.80278605 |
99 | MP0002148_abnormal_hypersensitivity_rea | 0.79534834 |
100 | MP0001188_hyperpigmentation | 0.79498603 |
101 | MP0002102_abnormal_ear_morphology | 0.78772675 |
102 | MP0001502_abnormal_circadian_rhythm | 0.78353610 |
103 | MP0000566_synostosis | 0.77788256 |
104 | MP0010678_abnormal_skin_adnexa | 0.77350563 |
105 | MP0005464_abnormal_platelet_physiology | 0.76261766 |
106 | MP0005646_abnormal_pituitary_gland | 0.75601606 |
107 | MP0002938_white_spotting | 0.75410850 |
108 | MP0001800_abnormal_humoral_immune | 0.74900188 |
109 | MP0006072_abnormal_retinal_apoptosis | 0.72907958 |
110 | MP0000383_abnormal_hair_follicle | 0.72902138 |
111 | MP0008004_abnormal_stomach_pH | 0.72860370 |
112 | MP0001661_extended_life_span | 0.72257963 |
113 | MP0002751_abnormal_autonomic_nervous | 0.71970780 |
114 | MP0003861_abnormal_nervous_system | 0.71150128 |
115 | MP0009785_altered_susceptibility_to | 0.70268130 |
116 | MP0001346_abnormal_lacrimal_gland | 0.70089445 |
117 | MP0001177_atelectasis | 0.70065054 |
118 | MP0000747_muscle_weakness | 0.69203073 |
119 | MP0003137_abnormal_impulse_conducting | 0.68650985 |
120 | MP0005253_abnormal_eye_physiology | 0.68532786 |
121 | MP0004133_heterotaxia | 0.68299732 |
122 | MP0008260_abnormal_autophagy | 0.68170746 |
123 | MP0009765_abnormal_xenobiotic_induced | 0.68130081 |
124 | MP0000372_irregular_coat_pigmentation | 0.67508270 |
125 | MP0003195_calcinosis | 0.66456236 |
126 | MP0003937_abnormal_limbs/digits/tail_de | 0.66208376 |
127 | MP0000569_abnormal_digit_pigmentation | 0.66046699 |
128 | MP0005167_abnormal_blood-brain_barrier | 0.65795647 |
129 | MP0000647_abnormal_sebaceous_gland | 0.65599620 |
130 | MP0002909_abnormal_adrenal_gland | 0.65388071 |
131 | MP0001764_abnormal_homeostasis | 0.64094960 |
132 | MP0008995_early_reproductive_senescence | 0.63620748 |
133 | MP0002723_abnormal_immune_serum | 0.63494793 |
134 | MP0002090_abnormal_vision | 0.62572404 |
135 | MP0006036_abnormal_mitochondrial_physio | 0.62212326 |
136 | MP0000465_gastrointestinal_hemorrhage | 0.61893033 |
137 | MP0003806_abnormal_nucleotide_metabolis | 0.61646326 |
138 | MP0001348_abnormal_lacrimal_gland | 0.61467214 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 5.78320634 |
2 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 5.78320634 |
3 | Sensory axonal neuropathy (HP:0003390) | 5.60830269 |
4 | Neurofibrillary tangles (HP:0002185) | 5.23944944 |
5 | Abnormality of the corticospinal tract (HP:0002492) | 4.66591737 |
6 | Polyphagia (HP:0002591) | 4.29802192 |
7 | Parakeratosis (HP:0001036) | 4.07902879 |
8 | Abnormality of glycolysis (HP:0004366) | 4.05217936 |
9 | Increased serum pyruvate (HP:0003542) | 4.05217936 |
10 | Febrile seizures (HP:0002373) | 4.02970837 |
11 | Cerebral inclusion bodies (HP:0100314) | 3.94602583 |
12 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.91508319 |
13 | Myokymia (HP:0002411) | 3.83771543 |
14 | Peripheral hypomyelination (HP:0007182) | 3.67087929 |
15 | Spastic gait (HP:0002064) | 3.52850609 |
16 | Focal motor seizures (HP:0011153) | 3.52320831 |
17 | Supranuclear gaze palsy (HP:0000605) | 3.50283555 |
18 | Cerebral hypomyelination (HP:0006808) | 3.44996977 |
19 | Akinesia (HP:0002304) | 3.36116627 |
20 | Atonic seizures (HP:0010819) | 3.30866177 |
21 | Failure to thrive in infancy (HP:0001531) | 3.29649829 |
22 | Dysmetria (HP:0001310) | 3.06057121 |
23 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.05093660 |
24 | Epileptic encephalopathy (HP:0200134) | 3.03235115 |
25 | Leukodystrophy (HP:0002415) | 3.00174405 |
26 | Intention tremor (HP:0002080) | 2.98565008 |
27 | Insidious onset (HP:0003587) | 2.92850267 |
28 | Termporal pattern (HP:0011008) | 2.92850267 |
29 | Mutism (HP:0002300) | 2.90379208 |
30 | Hyperventilation (HP:0002883) | 2.89890295 |
31 | Urinary urgency (HP:0000012) | 2.87366146 |
32 | Alacrima (HP:0000522) | 2.81177812 |
33 | Onion bulb formation (HP:0003383) | 2.77928712 |
34 | Lissencephaly (HP:0001339) | 2.76825550 |
35 | Thickened helices (HP:0000391) | 2.72868402 |
36 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.71868354 |
37 | Abnormal eating behavior (HP:0100738) | 2.70033345 |
38 | Abnormal auditory evoked potentials (HP:0006958) | 2.63227928 |
39 | Abnormality of the labia minora (HP:0012880) | 2.60760084 |
40 | Agitation (HP:0000713) | 2.59195452 |
41 | Retinal dysplasia (HP:0007973) | 2.59160663 |
42 | Acute necrotizing encephalopathy (HP:0006965) | 2.58042690 |
43 | Scanning speech (HP:0002168) | 2.56133343 |
44 | Generalized tonic-clonic seizures (HP:0002069) | 2.56082430 |
45 | Pheochromocytoma (HP:0002666) | 2.55354063 |
46 | Amyotrophic lateral sclerosis (HP:0007354) | 2.52865684 |
47 | Hepatic necrosis (HP:0002605) | 2.48313288 |
48 | Hypoplastic pelvis (HP:0008839) | 2.46082131 |
49 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.41304820 |
50 | Focal seizures (HP:0007359) | 2.41145714 |
51 | Renal Fanconi syndrome (HP:0001994) | 2.39730741 |
52 | Absent septum pellucidum (HP:0001331) | 2.37235158 |
53 | Hyperglycinemia (HP:0002154) | 2.32392769 |
54 | Ankle clonus (HP:0011448) | 2.29080616 |
55 | Vaginal atresia (HP:0000148) | 2.27298345 |
56 | Gait imbalance (HP:0002141) | 2.26113331 |
57 | Broad-based gait (HP:0002136) | 2.24604124 |
58 | Hypsarrhythmia (HP:0002521) | 2.23961783 |
59 | Neuroendocrine neoplasm (HP:0100634) | 2.22675797 |
60 | Slow saccadic eye movements (HP:0000514) | 2.22332458 |
61 | Epileptiform EEG discharges (HP:0011182) | 2.21303363 |
62 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.20998329 |
63 | Hypoplasia of the brainstem (HP:0002365) | 2.20998329 |
64 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.19865957 |
65 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.19865957 |
66 | EEG with generalized epileptiform discharges (HP:0011198) | 2.19788287 |
67 | Decreased lacrimation (HP:0000633) | 2.18944947 |
68 | Amblyopia (HP:0000646) | 2.18207003 |
69 | Genital tract atresia (HP:0001827) | 2.17025657 |
70 | Partial agenesis of the corpus callosum (HP:0001338) | 2.16664557 |
71 | Spastic paraparesis (HP:0002313) | 2.16536998 |
72 | Mitochondrial inheritance (HP:0001427) | 2.15354962 |
73 | Autoamputation (HP:0001218) | 2.15238407 |
74 | Progressive macrocephaly (HP:0004481) | 2.11988136 |
75 | Cerebral hemorrhage (HP:0001342) | 2.11794398 |
76 | Poor suck (HP:0002033) | 2.11339289 |
77 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.10984021 |
78 | Abnormality of the septum pellucidum (HP:0007375) | 2.10811084 |
79 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.07809927 |
80 | Spastic tetraplegia (HP:0002510) | 2.06551216 |
81 | Anteriorly placed anus (HP:0001545) | 2.06471876 |
82 | Medial flaring of the eyebrow (HP:0010747) | 2.06424050 |
83 | Diplopia (HP:0000651) | 2.05878507 |
84 | Abnormality of binocular vision (HP:0011514) | 2.05878507 |
85 | Stridor (HP:0010307) | 2.05230624 |
86 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.05054006 |
87 | Dialeptic seizures (HP:0011146) | 2.04305930 |
88 | Anomalous pulmonary venous return (HP:0010772) | 2.04217520 |
89 | Acute encephalopathy (HP:0006846) | 2.03885956 |
90 | Esotropia (HP:0000565) | 2.03691692 |
91 | Lipid accumulation in hepatocytes (HP:0006561) | 2.03158380 |
92 | Drooling (HP:0002307) | 2.02738563 |
93 | Increased intramyocellular lipid droplets (HP:0012240) | 2.02424196 |
94 | Premature skin wrinkling (HP:0100678) | 2.02245623 |
95 | 3-Methylglutaconic aciduria (HP:0003535) | 2.02137589 |
96 | Hypomagnesemia (HP:0002917) | 2.02007793 |
97 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.99885523 |
98 | Cortical dysplasia (HP:0002539) | 1.99857258 |
99 | Pachygyria (HP:0001302) | 1.99352555 |
100 | Stomatitis (HP:0010280) | 1.98620344 |
101 | Split foot (HP:0001839) | 1.97587817 |
102 | Excessive salivation (HP:0003781) | 1.97564085 |
103 | Lower limb muscle weakness (HP:0007340) | 1.96687688 |
104 | Status epilepticus (HP:0002133) | 1.95803539 |
105 | Generalized myoclonic seizures (HP:0002123) | 1.94857752 |
106 | Emotional lability (HP:0000712) | 1.94018159 |
107 | Methylmalonic acidemia (HP:0002912) | 1.93730608 |
108 | Increased circulating renin level (HP:0000848) | 1.93170832 |
109 | Optic disc pallor (HP:0000543) | 1.91432025 |
110 | Clumsiness (HP:0002312) | 1.91117838 |
111 | Poor speech (HP:0002465) | 1.90358551 |
112 | Congenital primary aphakia (HP:0007707) | 1.90283061 |
113 | Gaze-evoked nystagmus (HP:0000640) | 1.88612285 |
114 | True hermaphroditism (HP:0010459) | 1.88546825 |
115 | Diminished movement (HP:0002374) | 1.88458195 |
116 | Generalized aminoaciduria (HP:0002909) | 1.87853265 |
117 | Pancreatic cysts (HP:0001737) | 1.86893621 |
118 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.86622000 |
119 | CNS hypomyelination (HP:0003429) | 1.86376389 |
120 | Molar tooth sign on MRI (HP:0002419) | 1.85197224 |
121 | Abnormality of midbrain morphology (HP:0002418) | 1.85197224 |
122 | Septo-optic dysplasia (HP:0100842) | 1.83574951 |
123 | Cupped ear (HP:0000378) | 1.83261734 |
124 | Delusions (HP:0000746) | 1.82797082 |
125 | Action tremor (HP:0002345) | 1.81787190 |
126 | Hepatocellular necrosis (HP:0001404) | 1.81379218 |
127 | Absence seizures (HP:0002121) | 1.81293910 |
128 | Abnormal hair whorl (HP:0010721) | 1.80706285 |
129 | Increased hepatocellular lipid droplets (HP:0006565) | 1.80481434 |
130 | Hemiparesis (HP:0001269) | 1.80267130 |
131 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.79791188 |
132 | Progressive cerebellar ataxia (HP:0002073) | 1.79690284 |
133 | Megalencephaly (HP:0001355) | 1.79235470 |
134 | Nephrogenic diabetes insipidus (HP:0009806) | 1.77961907 |
135 | Methylmalonic aciduria (HP:0012120) | 1.77708669 |
136 | Morphological abnormality of the inner ear (HP:0011390) | 1.77279693 |
137 | Inability to walk (HP:0002540) | 1.75908296 |
138 | Acute hepatic failure (HP:0006554) | 1.74335466 |
139 | Bowel incontinence (HP:0002607) | 1.72811514 |
140 | Infantile muscular hypotonia (HP:0008947) | 1.71808965 |
141 | Coronal craniosynostosis (HP:0004440) | 1.70885200 |
142 | Increased serum lactate (HP:0002151) | 1.70291683 |
143 | Progressive inability to walk (HP:0002505) | 1.70165157 |
144 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.69944051 |
145 | Adrenal hypoplasia (HP:0000835) | 1.69559976 |
146 | Progressive microcephaly (HP:0000253) | 1.69037280 |
147 | Abnormality of the pulmonary veins (HP:0011718) | 1.68874219 |
148 | Specific learning disability (HP:0001328) | 1.67855201 |
149 | Widely spaced teeth (HP:0000687) | 1.67687046 |
150 | Erythroderma (HP:0001019) | 1.67628906 |
151 | White forelock (HP:0002211) | 1.67424333 |
152 | Absent speech (HP:0001344) | 1.66883337 |
153 | Lactic acidosis (HP:0003128) | 1.66503202 |
154 | Exertional dyspnea (HP:0002875) | 1.66055465 |
155 | Dysdiadochokinesis (HP:0002075) | 1.65701298 |
156 | Increased CSF lactate (HP:0002490) | 1.65130675 |
157 | Limb dystonia (HP:0002451) | 1.64206287 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STK39 | 5.18325464 |
2 | OXSR1 | 4.24057583 |
3 | BCR | 3.20947193 |
4 | CDK19 | 3.09471656 |
5 | TNIK | 3.02536846 |
6 | CASK | 3.00935986 |
7 | PRPF4B | 2.63807407 |
8 | BCKDK | 2.50502506 |
9 | PKN1 | 2.29553075 |
10 | MAP4K2 | 2.27135172 |
11 | MARK1 | 2.22780828 |
12 | EPHA4 | 2.21398781 |
13 | EPHB1 | 2.21324041 |
14 | PINK1 | 2.19099730 |
15 | UHMK1 | 2.13435505 |
16 | WNK4 | 2.00605514 |
17 | SIK2 | 2.00538977 |
18 | MAP3K11 | 1.92926716 |
19 | CSNK1G3 | 1.86554422 |
20 | LIMK1 | 1.83627547 |
21 | TAOK3 | 1.78781793 |
22 | FGFR2 | 1.70404010 |
23 | CSNK1A1L | 1.69396837 |
24 | CSNK1G2 | 1.57007095 |
25 | CAMK2B | 1.52875236 |
26 | NEK6 | 1.51632776 |
27 | MAP3K12 | 1.51617951 |
28 | NTRK1 | 1.48495680 |
29 | MET | 1.46042939 |
30 | WNK1 | 1.44635959 |
31 | TYRO3 | 1.43212547 |
32 | MAPK13 | 1.43130695 |
33 | PNCK | 1.38283772 |
34 | DYRK2 | 1.37602409 |
35 | PAK6 | 1.37169204 |
36 | PBK | 1.35519193 |
37 | FGR | 1.34546896 |
38 | ROCK2 | 1.33934979 |
39 | TXK | 1.33779093 |
40 | CSNK1G1 | 1.32937908 |
41 | NTRK3 | 1.32777199 |
42 | ICK | 1.30153957 |
43 | TESK1 | 1.29569008 |
44 | TAOK1 | 1.28734093 |
45 | TRIM28 | 1.27559002 |
46 | VRK1 | 1.26555930 |
47 | BMPR1B | 1.18082257 |
48 | DAPK1 | 1.16237941 |
49 | MAPKAPK5 | 1.16105393 |
50 | CAMKK2 | 1.14100366 |
51 | CAMK2D | 1.13326048 |
52 | VRK2 | 1.10716819 |
53 | PIM2 | 1.08797473 |
54 | SGK494 | 1.07901529 |
55 | SGK223 | 1.07901529 |
56 | TAOK2 | 1.07508787 |
57 | CDK14 | 1.06953123 |
58 | DYRK3 | 1.06658873 |
59 | CDK5 | 1.05607636 |
60 | MST4 | 1.03280485 |
61 | TLK1 | 1.02917326 |
62 | MAP4K1 | 1.00725947 |
63 | SYK | 0.99963086 |
64 | MATK | 0.97785636 |
65 | MARK2 | 0.96031998 |
66 | CAMK2A | 0.95856975 |
67 | MAP3K4 | 0.95564847 |
68 | CDK18 | 0.93497065 |
69 | CAMKK1 | 0.93106151 |
70 | CDK15 | 0.92839918 |
71 | EPHA3 | 0.92123727 |
72 | NTRK2 | 0.91249320 |
73 | ARAF | 0.88317215 |
74 | TESK2 | 0.86740536 |
75 | SIK3 | 0.85983563 |
76 | NME1 | 0.85766138 |
77 | GRK5 | 0.85324385 |
78 | CAMK2G | 0.83689284 |
79 | CDK11A | 0.82578600 |
80 | PLK2 | 0.82033233 |
81 | KDR | 0.81045482 |
82 | CLK1 | 0.80621813 |
83 | MAP3K9 | 0.80534908 |
84 | MUSK | 0.79401809 |
85 | MINK1 | 0.79005239 |
86 | MAP3K5 | 0.78645632 |
87 | MAP2K7 | 0.78403448 |
88 | RPS6KA5 | 0.77326341 |
89 | FES | 0.76427888 |
90 | ADRBK2 | 0.75508728 |
91 | PAK3 | 0.75113027 |
92 | PRKCE | 0.70769009 |
93 | ERBB3 | 0.70057630 |
94 | PHKG2 | 0.67407957 |
95 | PHKG1 | 0.67407957 |
96 | GRK7 | 0.66799120 |
97 | DAPK2 | 0.66360031 |
98 | PRKCQ | 0.64496231 |
99 | RIPK4 | 0.64203501 |
100 | DAPK3 | 0.62436611 |
101 | SRPK1 | 0.61172429 |
102 | LYN | 0.60717520 |
103 | BTK | 0.60528469 |
104 | IRAK2 | 0.59741137 |
105 | KIT | 0.58839822 |
106 | DYRK1A | 0.58646529 |
107 | INSRR | 0.57065984 |
108 | FYN | 0.56152068 |
109 | KSR2 | 0.56135064 |
110 | PRKCG | 0.53485345 |
111 | PRKCZ | 0.53393400 |
112 | MAPK7 | 0.52297847 |
113 | ERBB4 | 0.50703474 |
114 | ITK | 0.49455275 |
115 | ZAK | 0.47893857 |
116 | PDPK1 | 0.47783157 |
117 | LCK | 0.47060851 |
118 | CCNB1 | 0.46699561 |
119 | BMPR2 | 0.43779191 |
120 | PTK2B | 0.43369828 |
121 | PRKG1 | 0.43104890 |
122 | WNK3 | 0.41593867 |
123 | NUAK1 | 0.40958689 |
124 | PRKD1 | 0.39425246 |
125 | STK16 | 0.38401504 |
126 | CSNK1D | 0.37662205 |
127 | STK11 | 0.37520448 |
128 | TEC | 0.37492810 |
129 | MAPK12 | 0.37015949 |
130 | CSNK1A1 | 0.36050287 |
131 | MAPKAPK3 | 0.35812663 |
132 | PRKCA | 0.35511351 |
133 | ADRBK1 | 0.35317951 |
134 | PRKACA | 0.35236710 |
135 | PRKACB | 0.34454928 |
136 | IRAK1 | 0.34243742 |
137 | MAP3K2 | 0.31393832 |
138 | KSR1 | 0.30384302 |
139 | MAP2K4 | 0.30049680 |
140 | PAK1 | 0.29254682 |
141 | ROCK1 | 0.27342385 |
142 | PRKCH | 0.25983666 |
143 | MAPK15 | 0.24853783 |
144 | GRK1 | 0.24569268 |
145 | EPHB2 | 0.24215582 |
146 | INSR | 0.23362546 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 4.91500944 |
2 | Steroid biosynthesis_Homo sapiens_hsa00100 | 3.89314925 |
3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.52589611 |
4 | Fatty acid elongation_Homo sapiens_hsa00062 | 3.42709927 |
5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.08589259 |
6 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.38909154 |
7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.29361606 |
8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.20943680 |
9 | Axon guidance_Homo sapiens_hsa04360 | 2.19976303 |
10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.08947083 |
11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.07459470 |
12 | Nicotine addiction_Homo sapiens_hsa05033 | 2.03304913 |
13 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.89873994 |
14 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.86351933 |
15 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.85610488 |
16 | GABAergic synapse_Homo sapiens_hsa04727 | 1.85357647 |
17 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.80837656 |
18 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.79360136 |
19 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.64895994 |
20 | Morphine addiction_Homo sapiens_hsa05032 | 1.59853491 |
21 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.57332393 |
22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.57233900 |
23 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.55581959 |
24 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.44228222 |
25 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.42230726 |
26 | Long-term depression_Homo sapiens_hsa04730 | 1.42054983 |
27 | Circadian entrainment_Homo sapiens_hsa04713 | 1.41794687 |
28 | Allograft rejection_Homo sapiens_hsa05330 | 1.37086673 |
29 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.36412062 |
30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36355313 |
31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.33599389 |
32 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.32696092 |
33 | Asthma_Homo sapiens_hsa05310 | 1.32476741 |
34 | Protein export_Homo sapiens_hsa03060 | 1.32257186 |
35 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.28938225 |
36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.23708315 |
37 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.20588446 |
38 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.19490540 |
39 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.18823392 |
40 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.15991942 |
41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.13105016 |
42 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.12545842 |
43 | Salivary secretion_Homo sapiens_hsa04970 | 1.06012118 |
44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.05832427 |
45 | Phototransduction_Homo sapiens_hsa04744 | 1.05301226 |
46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.03611525 |
47 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.01655932 |
48 | Long-term potentiation_Homo sapiens_hsa04720 | 1.00734637 |
49 | Taste transduction_Homo sapiens_hsa04742 | 1.00398589 |
50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.99492854 |
51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.97651929 |
52 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.92702022 |
53 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.92032928 |
54 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.91423963 |
55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85553080 |
56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83947622 |
57 | RNA polymerase_Homo sapiens_hsa03020 | 0.82796771 |
58 | Cocaine addiction_Homo sapiens_hsa05030 | 0.79963127 |
59 | Renin secretion_Homo sapiens_hsa04924 | 0.78446196 |
60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.77327508 |
61 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.76718619 |
62 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.75185966 |
63 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.74171456 |
64 | Tight junction_Homo sapiens_hsa04530 | 0.73545911 |
65 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.73487133 |
66 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.72741852 |
67 | Gap junction_Homo sapiens_hsa04540 | 0.72739654 |
68 | Phagosome_Homo sapiens_hsa04145 | 0.71514019 |
69 | Salmonella infection_Homo sapiens_hsa05132 | 0.70436136 |
70 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.70426526 |
71 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.69185494 |
72 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.69064909 |
73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67098284 |
74 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.65275005 |
75 | Histidine metabolism_Homo sapiens_hsa00340 | 0.64964334 |
76 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.62122182 |
77 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.61905147 |
78 | Endocytosis_Homo sapiens_hsa04144 | 0.61700435 |
79 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.61653390 |
80 | Viral myocarditis_Homo sapiens_hsa05416 | 0.61326833 |
81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.59858827 |
82 | Shigellosis_Homo sapiens_hsa05131 | 0.59495445 |
83 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.58849247 |
84 | Peroxisome_Homo sapiens_hsa04146 | 0.56375062 |
85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56369553 |
86 | Insulin secretion_Homo sapiens_hsa04911 | 0.56284263 |
87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.55806930 |
88 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.53523086 |
89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51217530 |
90 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.48655810 |
91 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48046656 |
92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.47214064 |
93 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.47163943 |
94 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.46861762 |
95 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.46683442 |
96 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.46127096 |
97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45995687 |
98 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.45548956 |
99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45029117 |
100 | Alcoholism_Homo sapiens_hsa05034 | 0.42851320 |
101 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.42850508 |
102 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41599391 |
103 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40905597 |
104 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.40332816 |
105 | RNA degradation_Homo sapiens_hsa03018 | 0.39728551 |
106 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.39028580 |
107 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38317844 |
108 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.37937864 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.36742728 |
110 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.36374850 |
111 | Melanogenesis_Homo sapiens_hsa04916 | 0.36138219 |
112 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36016583 |
113 | Tuberculosis_Homo sapiens_hsa05152 | 0.35893569 |
114 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.35624507 |
115 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34424998 |
116 | Metabolic pathways_Homo sapiens_hsa01100 | 0.34149767 |
117 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.33189349 |
118 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.32568745 |
119 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.31213858 |
120 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.29902791 |
121 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.29738807 |
122 | Base excision repair_Homo sapiens_hsa03410 | 0.29524462 |
123 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27982384 |
124 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27848461 |
125 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27062855 |
126 | Purine metabolism_Homo sapiens_hsa00230 | 0.26790493 |
127 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.26780000 |
128 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.26765290 |
129 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.26266786 |
130 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24191729 |
131 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22867811 |
132 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.22552243 |
133 | Proteasome_Homo sapiens_hsa03050 | 0.22455587 |
134 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.20547180 |
135 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.19277595 |