RAB35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)4.04640673
2regulation of translational termination (GO:0006449)4.00706802
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.00158069
4negative regulation of cell killing (GO:0031342)4.00158069
5response to peptidoglycan (GO:0032494)3.98096580
6positive regulation by symbiont of host defense response (GO:0052509)3.93579537
7modulation by symbiont of host defense response (GO:0052031)3.93579537
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.93579537
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.93579537
10positive regulation by organism of defense response of other organism involved in symbiotic interact3.93579537
11modulation by symbiont of host immune response (GO:0052553)3.93579537
12NIK/NF-kappaB signaling (GO:0038061)3.64602301
13heterochromatin organization (GO:0070828)3.53913353
14regulation of translational fidelity (GO:0006450)3.43162180
15positive regulation of histone deacetylation (GO:0031065)3.38052621
16positive regulation of gamma-delta T cell activation (GO:0046645)3.32923138
17macrophage activation involved in immune response (GO:0002281)3.32904985
18stress fiber assembly (GO:0043149)3.30837234
19lipopolysaccharide-mediated signaling pathway (GO:0031663)3.29187841
20positive regulation of lamellipodium assembly (GO:0010592)3.28797678
21antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.28781900
22regulation of early endosome to late endosome transport (GO:2000641)3.28661211
23negative regulation of cell size (GO:0045792)3.27349906
24response to muramyl dipeptide (GO:0032495)3.27232720
25negative regulation of interleukin-12 production (GO:0032695)3.26912500
26* protein localization to endosome (GO:0036010)3.21877481
27negative regulation of histone methylation (GO:0031061)3.19847668
28cytoskeletal anchoring at plasma membrane (GO:0007016)3.18793969
29peptidyl-arginine omega-N-methylation (GO:0035247)3.16938655
30antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.16214560
31regulation of NFAT protein import into nucleus (GO:0051532)3.15041374
32positive regulation of Cdc42 GTPase activity (GO:0043089)3.14257355
33mitotic G1 DNA damage checkpoint (GO:0031571)3.13682360
34modulation by symbiont of host cellular process (GO:0044068)3.13382569
35peptidyl-lysine dimethylation (GO:0018027)3.06756243
36RNA stabilization (GO:0043489)3.05436167
37mRNA stabilization (GO:0048255)3.05436167
38mannose metabolic process (GO:0006013)3.04353256
39intracellular estrogen receptor signaling pathway (GO:0030520)3.03659122
40barbed-end actin filament capping (GO:0051016)3.03318832
41maternal placenta development (GO:0001893)3.02575484
42adherens junction assembly (GO:0034333)3.01196838
43peptidyl-arginine N-methylation (GO:0035246)3.00247336
44peptidyl-arginine methylation (GO:0018216)3.00247336
45regulation of RNA export from nucleus (GO:0046831)2.99331085
46regulation of type I interferon-mediated signaling pathway (GO:0060338)2.99316550
47detection of other organism (GO:0098543)2.98652688
48regulation of hippo signaling (GO:0035330)2.98541529
49germinal center formation (GO:0002467)2.98362486
50antigen processing and presentation of endogenous antigen (GO:0019883)2.98315021
51NLS-bearing protein import into nucleus (GO:0006607)2.97357158
52pinocytosis (GO:0006907)2.96839697
53trophectodermal cell differentiation (GO:0001829)2.94940986
54apoptotic process involved in morphogenesis (GO:0060561)2.92500573
55negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.91579445
56cytoplasmic mRNA processing body assembly (GO:0033962)2.91559610
57nuclear pore complex assembly (GO:0051292)2.91356747
58protein localization to kinetochore (GO:0034501)2.90310383
59regulation of interferon-beta biosynthetic process (GO:0045357)2.89898679
60regulation of clathrin-mediated endocytosis (GO:2000369)2.85748055
61detection of bacterium (GO:0016045)2.84690727
62cell-substrate adherens junction assembly (GO:0007045)2.81302413
63focal adhesion assembly (GO:0048041)2.81302413
64myeloid dendritic cell differentiation (GO:0043011)2.80786130
65regulation of leukocyte degranulation (GO:0043300)2.80490958
66neutrophil activation involved in immune response (GO:0002283)2.79442584
67COPI coating of Golgi vesicle (GO:0048205)2.79090315
68Golgi transport vesicle coating (GO:0048200)2.79090315
69regulation of T-helper 2 cell differentiation (GO:0045628)2.77423099
70positive regulation of lamellipodium organization (GO:1902745)2.76212974
71positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.75156878
72antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.75041236
73detection of molecule of bacterial origin (GO:0032490)2.73074026
74sodium ion export (GO:0071436)2.72924864
75mitotic G1/S transition checkpoint (GO:0044819)2.71234179
76positive regulation of SMAD protein import into nucleus (GO:0060391)2.70750946
77modulation by virus of host process (GO:0019054)2.69610333
78regulation of posttranscriptional gene silencing (GO:0060147)2.69350640
79regulation of gene silencing by miRNA (GO:0060964)2.69350640
80regulation of gene silencing by RNA (GO:0060966)2.69350640
81regulation of nucleobase-containing compound transport (GO:0032239)2.68961093
82positive thymic T cell selection (GO:0045059)2.68752986
83activation of MAPKKK activity (GO:0000185)2.68697403
84nuclear pore organization (GO:0006999)2.67920819
85type I interferon signaling pathway (GO:0060337)2.67269764
86cellular response to type I interferon (GO:0071357)2.67269764
87cortical actin cytoskeleton organization (GO:0030866)2.66549742
88glucocorticoid receptor signaling pathway (GO:0042921)2.64693473
89detection of external biotic stimulus (GO:0098581)2.64565308
90response to type I interferon (GO:0034340)2.64307430
91positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.62887286
92plasma membrane repair (GO:0001778)2.62708344
93G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.62599025
94regulation of ARF GTPase activity (GO:0032312)2.62256834
95positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.61619299
963-UTR-mediated mRNA stabilization (GO:0070935)2.60772821
97leukocyte aggregation (GO:0070486)2.59795287
98spliceosomal tri-snRNP complex assembly (GO:0000244)2.58262126
99negative regulation of nucleotide catabolic process (GO:0030812)2.57670898
100epithelial cell differentiation involved in prostate gland development (GO:0060742)2.55745141
101response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.55680766
102response to host (GO:0075136)2.55680766
103response to host defenses (GO:0052200)2.55680766
104DNA unwinding involved in DNA replication (GO:0006268)2.55395110
105nuclear envelope disassembly (GO:0051081)2.55238656
106membrane disassembly (GO:0030397)2.55238656
107negative regulation of toll-like receptor signaling pathway (GO:0034122)2.55101522
108chromatin assembly (GO:0031497)2.55064236
109regulation of mast cell degranulation (GO:0043304)2.54476211
110dosage compensation (GO:0007549)2.54268954
111positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.54234639
112mitotic nuclear envelope disassembly (GO:0007077)2.52709554
113regulation of defense response to virus by virus (GO:0050690)2.51423260
114response to laminar fluid shear stress (GO:0034616)2.51349213
115negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.51323890
116establishment of apical/basal cell polarity (GO:0035089)2.51028023
117positive regulation of protein deacetylation (GO:0090312)2.50915464
118G1 DNA damage checkpoint (GO:0044783)2.50517665
119response to host immune response (GO:0052572)2.50092642
120response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.50092642
121regulation of vitamin D biosynthetic process (GO:0060556)2.49993899
122immunoglobulin mediated immune response (GO:0016064)2.48997837
123regulation of superoxide anion generation (GO:0032928)2.48663643
124activation of Rac GTPase activity (GO:0032863)2.48539160
125embryonic process involved in female pregnancy (GO:0060136)2.47898479
126signal complex assembly (GO:0007172)2.47523882
127negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.46878215
128regulation of necroptotic process (GO:0060544)2.45941382
129corticosteroid receptor signaling pathway (GO:0031958)2.45686956
130immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00022.44994843
131Fc-gamma receptor signaling pathway (GO:0038094)2.44994843
132Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)2.44994843
133histone H2A monoubiquitination (GO:0035518)2.44763859
134positive regulation of gene expression, epigenetic (GO:0045815)2.43717667
135Fc receptor mediated stimulatory signaling pathway (GO:0002431)2.43297117
136regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.42930352
137positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.42917303
138regulation of myeloid leukocyte mediated immunity (GO:0002886)2.42747358
139thymic T cell selection (GO:0045061)2.41986189
140activation of JUN kinase activity (GO:0007257)2.41870646
141regulation of SMAD protein import into nucleus (GO:0060390)2.41476244
142endothelial tube morphogenesis (GO:0061154)2.40998289
143morphogenesis of an endothelium (GO:0003159)2.40998289
144natural killer cell differentiation (GO:0001779)2.40621145
145glycosphingolipid catabolic process (GO:0046479)2.39587468
146nodal signaling pathway (GO:0038092)2.39491971
147histone arginine methylation (GO:0034969)2.39418535
148positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.37192168
149cellular response to virus (GO:0098586)2.37122021
150cell-substrate junction assembly (GO:0007044)2.36977018
151regulation of gamma-delta T cell differentiation (GO:0045586)2.36569722
152positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.36413496
153protein localization to chromosome, centromeric region (GO:0071459)2.36313253
154myeloid dendritic cell activation (GO:0001773)2.36156766
155negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.36056641
156regulation of tight junction assembly (GO:2000810)2.35837517
157positive regulation of cellular amide metabolic process (GO:0034250)2.35801521
158cellular extravasation (GO:0045123)2.35032268
159negative regulation of fatty acid transport (GO:2000192)2.34723475
160regulation of integrin activation (GO:0033623)2.34279473
161regulation of gamma-delta T cell activation (GO:0046643)2.33827265
162positive regulation of chromosome segregation (GO:0051984)2.33807346
163negative regulation of erythrocyte differentiation (GO:0045647)2.33485967
164negative regulation of cardiac muscle tissue growth (GO:0055022)2.33074260
165negative regulation of heart growth (GO:0061117)2.33074260
166pentose-phosphate shunt (GO:0006098)2.33045512
167skin morphogenesis (GO:0043589)2.32953755
168hepatocyte apoptotic process (GO:0097284)2.32514223
169T cell apoptotic process (GO:0070231)2.32107558
170Arp2/3 complex-mediated actin nucleation (GO:0034314)2.31514464
171detection of biotic stimulus (GO:0009595)2.30907902
172regulation of sister chromatid cohesion (GO:0007063)2.30820613
173negative regulation of viral release from host cell (GO:1902187)2.26052282
174regulation of necrotic cell death (GO:0010939)2.25364484
175negative regulation of cytokine production involved in immune response (GO:0002719)2.24671596
176regulation of regulated secretory pathway (GO:1903305)2.23146753
177regulation of mammary gland epithelial cell proliferation (GO:0033599)2.21454314
178negative regulation of necroptotic process (GO:0060546)2.21289957
179positive regulation of leukocyte degranulation (GO:0043302)2.20725120
180regulation of podosome assembly (GO:0071801)2.20629516
181cellular response to thyroid hormone stimulus (GO:0097067)2.19987185
182regulation of dendritic cell antigen processing and presentation (GO:0002604)2.19172403

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human3.89347435
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.83514050
3* MYC_22102868_ChIP-Seq_BL_Human3.64010875
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.40336956
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.39435181
6VDR_21846776_ChIP-Seq_THP-1_Human2.84291346
7KDM2B_26808549_Chip-Seq_DND41_Human2.68037171
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.61441027
9TCF7_22412390_ChIP-Seq_EML_Mouse2.48009559
10KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.43077246
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.31362006
12ZNF263_19887448_ChIP-Seq_K562_Human2.26130641
13ELK3_25401928_ChIP-Seq_HUVEC_Human2.25091978
14* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.23097706
15ZFP281_18757296_ChIP-ChIP_E14_Mouse2.04346119
16LXR_22292898_ChIP-Seq_THP-1_Human2.02649217
17* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.92471281
18MAF_26560356_Chip-Seq_TH1_Human1.91474963
19EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.85004416
20* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.80791826
21RACK7_27058665_Chip-Seq_MCF-7_Human1.77518478
22* KDM2B_26808549_Chip-Seq_JURKAT_Human1.76829227
23ZFP281_27345836_Chip-Seq_ESCs_Mouse1.76343425
24* UTX_26944678_Chip-Seq_JUKART_Human1.75935319
25TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74484190
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.74083901
27KDM2B_26808549_Chip-Seq_K562_Human1.70821028
28IRF8_22096565_ChIP-ChIP_GC-B_Human1.70536847
29SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.68756423
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.66389654
31P300_27058665_Chip-Seq_ZR-75-30cells_Human1.66174938
32* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.65009218
33TP63_17297297_ChIP-ChIP_HaCaT_Human1.60669215
34* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.59699276
35ATF3_27146783_Chip-Seq_COLON_Human1.58119464
36ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.57537300
37NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57262824
38* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.52115260
39MYC_19079543_ChIP-ChIP_MESCs_Mouse1.51130749
40KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.50639545
41VDR_24763502_ChIP-Seq_THP-1_Human1.50291088
42IRF8_21731497_ChIP-ChIP_J774_Mouse1.48600945
43STAT4_19710469_ChIP-ChIP_TH1__Mouse1.46983273
44STAT3_1855785_ChIP-Seq_MESCs_Mouse1.43867066
45SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43119846
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.43054995
47SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.42144236
48* IRF8_27001747_Chip-Seq_BMDM_Mouse1.41526251
49* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.41514605
50* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.40575297
51RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.40368978
52TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.39657257
53NCOR1_26117541_ChIP-Seq_K562_Human1.39399965
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.39178402
55SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.39043762
56TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.37930929
57* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.37259962
58THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35165093
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.34865698
60MYB_21317192_ChIP-Seq_ERMYB_Mouse1.33792762
61SPI1_23127762_ChIP-Seq_K562_Human1.33519194
62PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.32958012
63* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.32440699
64* MAF_26560356_Chip-Seq_TH2_Human1.31960790
65CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.29680604
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.29233627
67RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28840971
68CREB1_26743006_Chip-Seq_LNCaP_Human1.28778271
69VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.28721224
70SPI1_23547873_ChIP-Seq_NB4_Human1.28363625
71SRY_22984422_ChIP-ChIP_TESTIS_Rat1.26980667
72WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.26222631
73* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.25540229
74PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25504191
75* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.24980908
76CTCF_27219007_Chip-Seq_ERYTHROID_Human1.24850506
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22964190
78DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.22364016
79HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22214346
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.21559221
81NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.21502075
82MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.19882290
83* RUNX1_22412390_ChIP-Seq_EML_Mouse1.19560822
84GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19095813
85TET1_21451524_ChIP-Seq_MESCs_Mouse1.19053328
86* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.18357465
87CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15285770
88NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.13979362
89* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.13555890
90GATA1_19941827_ChIP-Seq_MEL_Mouse1.13255639
91MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.12703854
92* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.11554598
93BP1_19119308_ChIP-ChIP_Hs578T_Human1.10021442
94STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.08969923
95* P68_20966046_ChIP-Seq_HELA_Human1.08812794
96NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.08153226
97MYC_18555785_ChIP-Seq_MESCs_Mouse1.07429921
98CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07249887
99TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06159875
100MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.06059684
101E2F4_17652178_ChIP-ChIP_JURKAT_Human1.05775270
102ELF1_20517297_ChIP-Seq_JURKAT_Human1.05644152
103CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05532149
104PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05450703
105SMC4_20622854_ChIP-Seq_HELA_Human1.05373205
106MYB_26560356_Chip-Seq_TH2_Human1.04034709
107GATA2_22383799_ChIP-Seq_G1ME_Mouse1.03871956
108TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03552329
109CLOCK_20551151_ChIP-Seq_293T_Human1.02750347
110TP53_22127205_ChIP-Seq_IMR90_Human1.02427341
111RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02127718
112SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.01999479
113* RUNX1_27514584_Chip-Seq_MCF-7_Human1.01850744
114FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.01482527
115TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00878753
116SCL_19346495_ChIP-Seq_HPC-7_Human1.00316577
117PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00215902
118NANOG_21062744_ChIP-ChIP_HESCs_Human1.00173689
119SA1_27219007_Chip-Seq_ERYTHROID_Human1.00071598
120CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.00050280
121TFEB_21752829_ChIP-Seq_HELA_Human0.99990667
122MYB_26560356_Chip-Seq_TH1_Human0.99936482
123SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.99610672
124* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.98978326
125UBF1/2_26484160_Chip-Seq_HMECs_Human0.98647857
126HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98477628
127NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.96758400
128FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.96559007
129GATA1_19941826_ChIP-Seq_K562_Human0.96076705
130SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.95652709
131* BCOR_27268052_Chip-Seq_Bcells_Human0.92987589
132CTCF_21964334_ChIP-Seq_BJAB-B_Human0.92678438
133TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.92225464
134FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92096081
135RARG_19884340_ChIP-ChIP_MEFs_Mouse0.91332121

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation4.28110389
2MP0003705_abnormal_hypodermis_morpholog4.23685167
3MP0010352_gastrointestinal_tract_polyps3.50131732
4MP0005076_abnormal_cell_differentiation3.30880243
5MP0005451_abnormal_body_composition3.01322473
6MP0010234_abnormal_vibrissa_follicle2.71862989
7MP0009278_abnormal_bone_marrow2.68719461
8MP0003300_gastrointestinal_ulcer2.67626636
9MP0010307_abnormal_tumor_latency2.34149238
10MP0003191_abnormal_cellular_cholesterol2.32761986
11MP0008260_abnormal_autophagy2.31888640
12MP0003566_abnormal_cell_adhesion2.25916497
13MP0004185_abnormal_adipocyte_glucose2.23484124
14MP0004510_myositis2.03163305
15MP0002419_abnormal_innate_immunity2.00313815
16MP0003724_increased_susceptibility_to1.98180211
17MP0004859_abnormal_synaptic_plasticity1.92479967
18MP0005025_abnormal_response_to1.86235870
19MP0002148_abnormal_hypersensitivity_rea1.70007148
20MP0009785_altered_susceptibility_to1.66727734
21MP0004957_abnormal_blastocyst_morpholog1.66518202
22MP0001730_embryonic_growth_arrest1.65203444
23MP0008961_abnormal_basal_metabolism1.62736405
24MP0001533_abnormal_skeleton_physiology1.62590984
25MP0003763_abnormal_thymus_physiology1.60314570
26MP0000350_abnormal_cell_proliferation1.58864175
27MP0003111_abnormal_nucleus_morphology1.55705507
28MP0004808_abnormal_hematopoietic_stem1.53841028
29MP0001545_abnormal_hematopoietic_system1.51068387
30MP0005397_hematopoietic_system_phenotyp1.51068387
31MP0004858_abnormal_nervous_system1.49923198
32MP0008438_abnormal_cutaneous_collagen1.44891676
33MP0005623_abnormal_meninges_morphology1.44571215
34MP0002086_abnormal_extraembryonic_tissu1.44345551
35MP0005671_abnormal_response_to1.44229307
36MP0003091_abnormal_cell_migration1.44052000
37MP0002998_abnormal_bone_remodeling1.44006954
38MP0001849_ear_inflammation1.42806337
39MP0003436_decreased_susceptibility_to1.40246901
40MP0005167_abnormal_blood-brain_barrier1.37484991
41MP0000685_abnormal_immune_system1.36321399
42MP0002084_abnormal_developmental_patter1.36199640
43MP0000733_abnormal_muscle_development1.35581194
44MP0002796_impaired_skin_barrier1.33939987
45MP0003077_abnormal_cell_cycle1.33585932
46MP0000604_amyloidosis1.33339623
47MP0004197_abnormal_fetal_growth/weight/1.32751429
48MP0000490_abnormal_crypts_of1.32315945
49MP0001697_abnormal_embryo_size1.31063359
50MP0001672_abnormal_embryogenesis/_devel1.30000256
51MP0005380_embryogenesis_phenotype1.30000256
52MP0003329_amyloid_beta_deposits1.29704999
53MP0002398_abnormal_bone_marrow1.29006197
54MP0002088_abnormal_embryonic_growth/wei1.25691808
55MP0004233_abnormal_muscle_weight1.25519811
56MP0001853_heart_inflammation1.25350200
57MP0003984_embryonic_growth_retardation1.25319344
58MP0005023_abnormal_wound_healing1.22247590
59MP0003453_abnormal_keratinocyte_physiol1.21021073
60MP0003693_abnormal_embryo_hatching1.20096025
61MP0004947_skin_inflammation1.19453375
62MP0000343_altered_response_to1.18385565
63MP0001845_abnormal_inflammatory_respons1.18156315
64MP0002080_prenatal_lethality1.17847539
65MP0003448_altered_tumor_morphology1.17788102
66MP0001800_abnormal_humoral_immune1.17097430
67MP0000703_abnormal_thymus_morphology1.16350454
68MP0006082_CNS_inflammation1.15964533
69MP0004130_abnormal_muscle_cell1.15670438
70MP0003221_abnormal_cardiomyocyte_apopto1.14380697
71MP0010630_abnormal_cardiac_muscle1.13979799
72MP0002085_abnormal_embryonic_tissue1.12850184
73MP0008770_decreased_survivor_rate1.12683628
74MP0005257_abnormal_intraocular_pressure1.12656308
75MP0002877_abnormal_melanocyte_morpholog1.11658233
76MP0009333_abnormal_splenocyte_physiolog1.11576660
77MP0002722_abnormal_immune_system1.11523770
78MP0004087_abnormal_muscle_fiber1.11354905
79MP0003123_paternal_imprinting1.09589112
80MP0000689_abnormal_spleen_morphology1.09106342
81MP0003828_pulmonary_edema1.07513925
82MP0002452_abnormal_antigen_presenting1.07123277
83MP0003075_altered_response_to1.06898081
84MP0003172_abnormal_lysosome_physiology1.06265363
85MP0000751_myopathy1.05159578
86MP0002405_respiratory_system_inflammati1.04873083
87MP0001348_abnormal_lacrimal_gland1.04541045
88MP0000750_abnormal_muscle_regeneration1.03543122
89MP0002019_abnormal_tumor_incidence1.03202146
90MP0003279_aneurysm1.02887119
91MP0000858_altered_metastatic_potential1.02763746
92MP0005310_abnormal_salivary_gland1.01876781
93MP0003283_abnormal_digestive_organ1.00318503
94MP0001915_intracranial_hemorrhage0.99664965
95MP0008469_abnormal_protein_level0.98921563
96MP0001790_abnormal_immune_system0.98195742
97MP0005387_immune_system_phenotype0.98195742
98MP0000747_muscle_weakness0.98066734
99MP0003119_abnormal_digestive_system0.96662815
100MP0002396_abnormal_hematopoietic_system0.96363471
101MP0005501_abnormal_skin_physiology0.96085390
102MP0001819_abnormal_immune_cell0.95780148
103MP0002420_abnormal_adaptive_immunity0.95407015
104MP0005409_darkened_coat_color0.94704161
105MP0001873_stomach_inflammation0.94568086
106MP0002925_abnormal_cardiovascular_devel0.94110155
107MP0005666_abnormal_adipose_tissue0.93835780
108MP0000716_abnormal_immune_system0.92595918
109MP0003183_abnormal_peptide_metabolism0.89993962
110MP0002254_reproductive_system_inflammat0.89255895
111MP0001216_abnormal_epidermal_layer0.87905532
112MP0002429_abnormal_blood_cell0.87859636
113MP0001851_eye_inflammation0.87834141
114MP0010094_abnormal_chromosome_stability0.87634673
115MP0009840_abnormal_foam_cell0.87091862
116MP0010155_abnormal_intestine_physiology0.86946068
117MP0005058_abnormal_lysosome_morphology0.86898075
118MP0000767_abnormal_smooth_muscle0.86517274
119MP0005464_abnormal_platelet_physiology0.86017945
120MP0005390_skeleton_phenotype0.85853571
121MP0000266_abnormal_heart_morphology0.84378206
122MP0002060_abnormal_skin_morphology0.82403768
123MP0005621_abnormal_cell_physiology0.82137006
124MP0002269_muscular_atrophy0.81667545
125MP0002089_abnormal_postnatal_growth/wei0.81068959
126MP0005000_abnormal_immune_tolerance0.79934141
127MP0001835_abnormal_antigen_presentation0.79744567
128MP0009764_decreased_sensitivity_to0.79646976
129MP0005375_adipose_tissue_phenotype0.79327270
130MP0002723_abnormal_immune_serum0.78868021
131MP0008874_decreased_physiological_sensi0.78816952
132MP0005166_decreased_susceptibility_to0.78619731
133MP0002653_abnormal_ependyma_morphology0.78075327
134MP0000477_abnormal_intestine_morphology0.77270501
135MP0000313_abnormal_cell_death0.77121027
136MP0001958_emphysema0.76800169
137MP0000678_abnormal_parathyroid_gland0.76104150
138MP0009931_abnormal_skin_appearance0.72885759
139MP0003795_abnormal_bone_structure0.72626995

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)4.04296781
2Hyperacusis (HP:0010780)3.65427664
3Abnormality of macrophages (HP:0004311)3.31137049
4Abnormality of glycolipid metabolism (HP:0010969)3.29573625
5Abnormality of liposaccharide metabolism (HP:0010968)3.29573625
6Abnormality of glycosphingolipid metabolism (HP:0004343)3.29573625
7Recurrent abscess formation (HP:0002722)3.02873057
8Recurrent bacterial skin infections (HP:0005406)3.00616307
9Ulnar bowing (HP:0003031)2.85024130
10Increased density of long bones (HP:0006392)2.75128138
11Annular pancreas (HP:0001734)2.70631008
12Achilles tendon contracture (HP:0001771)2.65768832
13Vertebral compression fractures (HP:0002953)2.62787580
14Dysostosis multiplex (HP:0000943)2.57036545
15Genu recurvatum (HP:0002816)2.56068367
16Insomnia (HP:0100785)2.51369492
17Premature rupture of membranes (HP:0001788)2.41928252
18Abnormality of the lower motor neuron (HP:0002366)2.41232085
19Shallow orbits (HP:0000586)2.40726665
20Distal upper limb amyotrophy (HP:0007149)2.39605252
21Upper limb amyotrophy (HP:0009129)2.39605252
22Mediastinal lymphadenopathy (HP:0100721)2.37638317
23Loss of speech (HP:0002371)2.37246285
24Distal lower limb amyotrophy (HP:0008944)2.34804309
25Abnormality of the Achilles tendon (HP:0005109)2.31734442
26Thin bony cortex (HP:0002753)2.31426573
27Facial hemangioma (HP:0000329)2.27203985
28Hand muscle atrophy (HP:0009130)2.27055286
29Hematochezia (HP:0002573)2.24449971
30Myositis (HP:0100614)2.23789835
31Dysmetric saccades (HP:0000641)2.23707002
32Cellulitis (HP:0100658)2.21758348
33Orchitis (HP:0100796)2.20921296
34Obstructive lung disease (HP:0006536)2.19939414
35Chronic obstructive pulmonary disease (HP:0006510)2.19939414
36Elfin facies (HP:0004428)2.19682808
37Pointed chin (HP:0000307)2.18401837
38Papilloma (HP:0012740)2.17319859
39Verrucae (HP:0200043)2.17319859
40Cerebral inclusion bodies (HP:0100314)2.15362624
41Polycythemia (HP:0001901)2.14513660
42Gingivitis (HP:0000230)2.14077328
43Segmental peripheral demyelination/remyelination (HP:0003481)2.12110568
44Interstitial pulmonary disease (HP:0006530)2.11900536
45Renal duplication (HP:0000075)2.11278107
46Apathy (HP:0000741)2.10866426
47Broad face (HP:0000283)2.10785390
48Long palpebral fissure (HP:0000637)2.10299724
49Neurofibrillary tangles (HP:0002185)2.09546038
50Gastrointestinal stroma tumor (HP:0100723)2.08914476
51Basal cell carcinoma (HP:0002671)2.08725053
52Hypercortisolism (HP:0001578)2.08663066
53Spontaneous hematomas (HP:0007420)2.08340602
54Mitral valve prolapse (HP:0001634)2.07951368
55Ependymoma (HP:0002888)2.05678265
56Short 1st metacarpal (HP:0010034)2.05419102
57Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.05419102
58Axonal loss (HP:0003447)2.04497645
59Heterotopia (HP:0002282)2.04358768
60Difficulty climbing stairs (HP:0003551)2.03916311
61Disinhibition (HP:0000734)2.02757961
62Recurrent gram-negative bacterial infections (HP:0005420)2.01756754
63Overriding aorta (HP:0002623)2.01095461
64Diminished motivation (HP:0000745)2.00862380
65Myocardial infarction (HP:0001658)2.00123135
66Emphysema (HP:0002097)1.99861685
67Abnormality of the astrocytes (HP:0100707)1.99067661
68Astrocytoma (HP:0009592)1.99067661
69Distal lower limb muscle weakness (HP:0009053)1.98621952
70Enlarged penis (HP:0000040)1.95538713
71Neuronal loss in central nervous system (HP:0002529)1.95431225
72Increased neuronal autofluorescent lipopigment (HP:0002074)1.95291453
73Abnormality of mucopolysaccharide metabolism (HP:0011020)1.95138326
74Abnormality of polysaccharide metabolism (HP:0011012)1.95138326
75Abnormality of glycosaminoglycan metabolism (HP:0004371)1.95138326
76Hypertensive crisis (HP:0100735)1.93629914
77Aneurysm (HP:0002617)1.93348094
78Centrally nucleated skeletal muscle fibers (HP:0003687)1.92766042
79Mucopolysacchariduria (HP:0008155)1.92694848
80Urinary glycosaminoglycan excretion (HP:0003541)1.92694848
81Polygenic inheritance (HP:0010982)1.92126246
82Disproportionate tall stature (HP:0001519)1.90024599
83Flat acetabular roof (HP:0003180)1.89697466
84Renovascular hypertension (HP:0100817)1.89387168
85Macroorchidism (HP:0000053)1.88664284
86Slow saccadic eye movements (HP:0000514)1.88365853
87Angiofibromas (HP:0010615)1.86964341
88Adenoma sebaceum (HP:0009720)1.86964341
89Upper motor neuron abnormality (HP:0002127)1.86764896
90Recurrent viral infections (HP:0004429)1.85122998
91Amyotrophic lateral sclerosis (HP:0007354)1.84983048
92Vertebral arch anomaly (HP:0008438)1.84864137
93Bone pain (HP:0002653)1.84157729
94Obstructive sleep apnea (HP:0002870)1.83998226
95Hemorrhage of the eye (HP:0011885)1.83885747
96Meningitis (HP:0001287)1.83124523
97Difficulty running (HP:0009046)1.83013744
98Colitis (HP:0002583)1.82619000
99Increased nuchal translucency (HP:0010880)1.82159685
100Frequent falls (HP:0002359)1.82055000
101Bowel diverticulosis (HP:0005222)1.81901300
102Increased connective tissue (HP:0009025)1.81457830
103Papilledema (HP:0001085)1.80822120
104Vacuolated lymphocytes (HP:0001922)1.79723532
105Abnormality of the thoracic spine (HP:0100711)1.79678743
106Urticaria (HP:0001025)1.78440852
107Striae distensae (HP:0001065)1.78349073
108Eczematoid dermatitis (HP:0000976)1.78021532
109Protrusio acetabuli (HP:0003179)1.76728222
110Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.76487247
111Dilatation of the ascending aorta (HP:0005111)1.76334930
112Abnormality of the 1st metacarpal (HP:0010009)1.76072106
113Thoracic kyphosis (HP:0002942)1.75798997
114Rectal prolapse (HP:0002035)1.75790524
115Supranuclear gaze palsy (HP:0000605)1.75657203
116Gastrointestinal infarctions (HP:0005244)1.75408738
117Nuclear cataract (HP:0100018)1.75359189
118Bowed forearm bones (HP:0003956)1.74491575
119Bowing of the arm (HP:0006488)1.74491575
120Amyloidosis (HP:0011034)1.74421764
121Recurrent skin infections (HP:0001581)1.74371340
122Pustule (HP:0200039)1.74048549
123Increased IgE level (HP:0003212)1.73771902
124Recurrent fungal infections (HP:0002841)1.73423355
125Systemic lupus erythematosus (HP:0002725)1.73118392
126Autoimmune thrombocytopenia (HP:0001973)1.72760895
127Fibroma (HP:0010614)1.72652219
128Retrobulbar optic neuritis (HP:0100654)1.71854643
129Optic neuritis (HP:0100653)1.71854643
130Rapidly progressive (HP:0003678)1.71635712
131Vasculitis (HP:0002633)1.71505800
132Increased serum ferritin (HP:0003281)1.71374104
133Fatigue (HP:0012378)1.71110692
134Hyperparathyroidism (HP:0000843)1.70046121
135Prominent nose (HP:0000448)1.69446390
136Cutaneous melanoma (HP:0012056)1.69232753
137Hallux valgus (HP:0001822)1.69077657
138Asymmetry of the thorax (HP:0001555)1.67355959
139Osteolytic defects of the phalanges of the hand (HP:0009771)1.67061068
140Osteolytic defects of the hand bones (HP:0009699)1.67061068
141Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.67057880
142Personality changes (HP:0000751)1.67003258
143Increased CSF protein (HP:0002922)1.66373681
144Bladder diverticulum (HP:0000015)1.65937524
145Syringomyelia (HP:0003396)1.64558771
146Spinal cord lesions (HP:0100561)1.64558771
147Blue sclerae (HP:0000592)1.63907881
148Abnormality of the distal phalanges of the toes (HP:0010182)1.63744358
149Fibrous tissue neoplasm (HP:0012316)1.63619718
150Ankle contracture (HP:0006466)1.63434353
151Resting tremor (HP:0002322)1.63223071
152Malignant gastrointestinal tract tumors (HP:0006749)1.63191171
153Gastrointestinal carcinoma (HP:0002672)1.63191171
154Subacute progressive viral hepatitis (HP:0006572)1.63186591
155Abnormality of the peritoneum (HP:0002585)1.62919255
156Cervical subluxation (HP:0003308)1.62320806
157Mitral regurgitation (HP:0001653)1.62195399
158Deviation of the hallux (HP:0010051)1.61777710
159Multiple enchondromatosis (HP:0005701)1.61151911
160Pseudobulbar signs (HP:0002200)1.60504769
161Deep palmar crease (HP:0006191)1.60248052
162Gastrointestinal inflammation (HP:0004386)1.59023650
163Radial bowing (HP:0002986)1.58728218
164Increased cerebral lipofuscin (HP:0011813)1.58651574
165Spinal muscular atrophy (HP:0007269)1.58071959
166Broad palm (HP:0001169)1.57290639
167Abnormality of the nasal mucosa (HP:0000433)1.56654171
168Short phalanx of the thumb (HP:0009660)1.55932535
169Abnormality of the motor neurons (HP:0002450)1.55779165
170Abnormal neuron morphology (HP:0012757)1.55779165
171EMG: neuropathic changes (HP:0003445)1.55379231
172Ankyloglossia (HP:0010296)1.53851543
173High pitched voice (HP:0001620)1.53693512
174Arnold-Chiari malformation (HP:0002308)1.53497073
175Lower limb amyotrophy (HP:0007210)1.52286945
176Bicuspid aortic valve (HP:0001647)1.51867827

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.77458613
2PRPF4B3.84733523
3PKN23.77375606
4MAP3K103.43933787
5EEF2K3.37020349
6IRAK33.18380464
7SMG12.83319489
8CDK122.69247833
9MAP4K12.41168477
10ALK2.39140476
11SIK12.23749159
12MAP3K92.23558955
13TAOK12.20728438
14NME21.95850817
15TYRO31.94303951
16TAOK21.93902056
17IRAK41.81371946
18MAP3K141.80323947
19GRK61.79647898
20BMX1.79493325
21TTN1.79291947
22KSR21.78376534
23LATS21.73964391
24MAP3K131.69992055
25STK101.66784275
26MAP3K31.65790108
27ICK1.57749176
28MAP3K111.57681923
29LRRK21.57240708
30SCYL21.49297988
31FGFR41.39144503
32RIPK11.38930734
33EPHB11.38409555
34PDGFRA1.34599689
35SIK21.33467474
36SIK31.33148437
37DMPK1.32102932
38ERN11.31104436
39ARAF1.25046890
40NEK21.16856711
41PTK61.12311438
42CDK61.12020702
43TESK11.07993025
44CAMKK11.07660945
45DDR21.05616580
46PAK61.05446786
47PRKD31.04334779
48MAP3K61.00240565
49NEK11.00011250
50MOS0.97916402
51PAK40.97834517
52MARK20.97216899
53MAP3K80.94278485
54FGR0.93667385
55IRAK20.92410290
56TGFBR20.90603272
57CDK40.87043437
58RIPK40.86831413
59RET0.85331370
60CDC70.84235493
61MTOR0.84123727
62ZAP700.83649114
63EPHA20.83497610
64CSK0.81005055
65BLK0.79846208
66PTK20.78353370
67MAP2K30.77588969
68STK380.77547809
69PRKD20.76864882
70CSF1R0.70436003
71RPS6KA40.69962931
72PIM20.69325447
73RPS6KB20.69235102
74PIM10.69146228
75TYK20.68502259
76HCK0.65952805
77STK110.65151106
78TGFBR10.64350975
79TESK20.63918629
80IKBKE0.61468360
81FES0.60628437
82DAPK20.60369809
83FGFR30.59721622
84PDGFRB0.59513989
85JAK20.59134331
86BRAF0.58354957
87KSR10.57919833
88PRKCH0.57863664
89BTK0.56995542
90PDK10.55565715
91CDC42BPA0.54777808
92RAF10.53656527
93DAPK10.53295877
94RPS6KA10.51736291
95IKBKB0.51244494
96LATS10.50270889
97CAMK1D0.49714817
98PAK20.49072821
99MATK0.48883167
100RPS6KA20.48670954
101ILK0.48252081
102MAPK120.44875202
103HIPK20.43483628
104STK30.43463391
105RPS6KL10.42795632
106RPS6KC10.42795632
107EGFR0.42783518
108NEK90.41995013
109DYRK1B0.41209548
110PRKG20.40907380
111SYK0.40014818
112MINK10.39933875
113MAP3K50.39050998
114TBK10.39027227
115CAMK1G0.38680777
116RPS6KA60.38632637
117CHEK10.38497345
118PDPK10.38236953
119CHUK0.38070055
120TTK0.37391411
121MAP3K10.37071790
122PRKD10.37059952
123MAPKAPK20.37041872
124CDK20.36797216
125MAP3K70.36602683
126MAP2K20.36470156
127MST1R0.36214965
128JAK10.36157501
129MAPKAPK30.34338711
130NTRK10.34254795
131DAPK30.33862293
132MAPK110.33678066
133JAK30.33619050

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.43433466
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.31329657
3Toll-like receptor signaling pathway_Homo sapiens_hsa046201.98249853
4mTOR signaling pathway_Homo sapiens_hsa041501.90214423
5Chronic myeloid leukemia_Homo sapiens_hsa052201.88708446
6Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.84683308
7Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.77375212
8B cell receptor signaling pathway_Homo sapiens_hsa046621.74742839
9Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.66909295
10VEGF signaling pathway_Homo sapiens_hsa043701.66411906
11Non-small cell lung cancer_Homo sapiens_hsa052231.62784870
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.55504059
13Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.53795658
14Glioma_Homo sapiens_hsa052141.53264612
15Neurotrophin signaling pathway_Homo sapiens_hsa047221.49158624
16Influenza A_Homo sapiens_hsa051641.44329402
17Acute myeloid leukemia_Homo sapiens_hsa052211.42567374
18Colorectal cancer_Homo sapiens_hsa052101.38117748
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37750686
20Pancreatic cancer_Homo sapiens_hsa052121.37497827
21Lysosome_Homo sapiens_hsa041421.36803786
22Dorso-ventral axis formation_Homo sapiens_hsa043201.36012848
23Endometrial cancer_Homo sapiens_hsa052131.34441946
24Osteoclast differentiation_Homo sapiens_hsa043801.33723537
25Prion diseases_Homo sapiens_hsa050201.31547390
26Hepatitis C_Homo sapiens_hsa051601.30226554
27Malaria_Homo sapiens_hsa051441.29859972
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.27029791
29Renal cell carcinoma_Homo sapiens_hsa052111.24451264
30AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.24077053
31Bladder cancer_Homo sapiens_hsa052191.19987975
32Proteoglycans in cancer_Homo sapiens_hsa052051.19677214
33Glycosaminoglycan degradation_Homo sapiens_hsa005311.19532128
34Estrogen signaling pathway_Homo sapiens_hsa049151.19135432
35Staphylococcus aureus infection_Homo sapiens_hsa051501.17749845
36Shigellosis_Homo sapiens_hsa051311.16019804
37Viral myocarditis_Homo sapiens_hsa054161.14999976
38Herpes simplex infection_Homo sapiens_hsa051681.13900784
39Leishmaniasis_Homo sapiens_hsa051401.13413172
40Adherens junction_Homo sapiens_hsa045201.12984444
41Central carbon metabolism in cancer_Homo sapiens_hsa052301.11762397
42Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10182070
43MicroRNAs in cancer_Homo sapiens_hsa052061.07387468
44Regulation of actin cytoskeleton_Homo sapiens_hsa048101.05902057
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.05526143
46Thyroid hormone signaling pathway_Homo sapiens_hsa049191.05385786
47Toxoplasmosis_Homo sapiens_hsa051451.04602671
48Small cell lung cancer_Homo sapiens_hsa052221.04394911
49Allograft rejection_Homo sapiens_hsa053301.04122749
50Legionellosis_Homo sapiens_hsa051341.03333088
51Platelet activation_Homo sapiens_hsa046111.03005667
52NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02881986
53Focal adhesion_Homo sapiens_hsa045101.02096158
54Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01684982
55GnRH signaling pathway_Homo sapiens_hsa049121.01484927
56Long-term potentiation_Homo sapiens_hsa047201.01183173
57Pertussis_Homo sapiens_hsa051331.01003212
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.00785900
59T cell receptor signaling pathway_Homo sapiens_hsa046600.99514646
60HIF-1 signaling pathway_Homo sapiens_hsa040660.99508474
61Phagosome_Homo sapiens_hsa041450.99467433
62mRNA surveillance pathway_Homo sapiens_hsa030150.99426705
63Oocyte meiosis_Homo sapiens_hsa041140.99096648
64Thyroid cancer_Homo sapiens_hsa052160.98993584
65Antigen processing and presentation_Homo sapiens_hsa046120.98897439
66Insulin signaling pathway_Homo sapiens_hsa049100.96242149
67ErbB signaling pathway_Homo sapiens_hsa040120.95820508
68Longevity regulating pathway - mammal_Homo sapiens_hsa042110.95372404
69Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.94569197
70Apoptosis_Homo sapiens_hsa042100.93376355
71Hepatitis B_Homo sapiens_hsa051610.90593342
72Tuberculosis_Homo sapiens_hsa051520.90481103
73* Endocytosis_Homo sapiens_hsa041440.90407349
74Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.89969521
75Graft-versus-host disease_Homo sapiens_hsa053320.89956107
76Chemokine signaling pathway_Homo sapiens_hsa040620.89892315
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88887853
78Prolactin signaling pathway_Homo sapiens_hsa049170.88744136
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88580162
80HTLV-I infection_Homo sapiens_hsa051660.88164032
81RNA transport_Homo sapiens_hsa030130.87886506
82Hippo signaling pathway_Homo sapiens_hsa043900.86207638
83Gap junction_Homo sapiens_hsa045400.86109944
84MAPK signaling pathway_Homo sapiens_hsa040100.85933183
85Viral carcinogenesis_Homo sapiens_hsa052030.85605074
86Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.85582201
87Pentose phosphate pathway_Homo sapiens_hsa000300.84653366
88Salmonella infection_Homo sapiens_hsa051320.83023076
89Autoimmune thyroid disease_Homo sapiens_hsa053200.82699099
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.82660408
91Notch signaling pathway_Homo sapiens_hsa043300.80715236
92Insulin resistance_Homo sapiens_hsa049310.80208607
93Gastric acid secretion_Homo sapiens_hsa049710.79538231
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.78836156
95Amoebiasis_Homo sapiens_hsa051460.78697054
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.77904094
97Primary immunodeficiency_Homo sapiens_hsa053400.75428167
98Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.75315655
99Oxytocin signaling pathway_Homo sapiens_hsa049210.74695267
100Rheumatoid arthritis_Homo sapiens_hsa053230.73826765
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73676558
102Galactose metabolism_Homo sapiens_hsa000520.73579661
103Fructose and mannose metabolism_Homo sapiens_hsa000510.72779419
104Rap1 signaling pathway_Homo sapiens_hsa040150.72673518
105African trypanosomiasis_Homo sapiens_hsa051430.72657828
106AMPK signaling pathway_Homo sapiens_hsa041520.71996462
107Adipocytokine signaling pathway_Homo sapiens_hsa049200.71608638
108FoxO signaling pathway_Homo sapiens_hsa040680.71586677
109Choline metabolism in cancer_Homo sapiens_hsa052310.70733254
110Type II diabetes mellitus_Homo sapiens_hsa049300.70453389
111Sphingolipid signaling pathway_Homo sapiens_hsa040710.70002620
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68712629
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67187871
114Cell cycle_Homo sapiens_hsa041100.66889188
115Vibrio cholerae infection_Homo sapiens_hsa051100.65121284
116Hematopoietic cell lineage_Homo sapiens_hsa046400.65010821
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64679907
118Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63420883
119Tight junction_Homo sapiens_hsa045300.63012320
120Synaptic vesicle cycle_Homo sapiens_hsa047210.60910680
121Intestinal immune network for IgA production_Homo sapiens_hsa046720.60797321
122Prostate cancer_Homo sapiens_hsa052150.60632952
123Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60258886
124Dilated cardiomyopathy_Homo sapiens_hsa054140.57741581
125TNF signaling pathway_Homo sapiens_hsa046680.57531810
126Nitrogen metabolism_Homo sapiens_hsa009100.57468684
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57292603
128Epstein-Barr virus infection_Homo sapiens_hsa051690.57155493
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56611654
130Measles_Homo sapiens_hsa051620.56490792
131p53 signaling pathway_Homo sapiens_hsa041150.55945268
132Pathways in cancer_Homo sapiens_hsa052000.55759718
133Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55750072
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55720756

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