

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | left/right pattern formation (GO:0060972) | 6.32860095 |
| 2 | cilium organization (GO:0044782) | 5.63991217 |
| 3 | cilium assembly (GO:0042384) | 5.47833910 |
| 4 | left/right axis specification (GO:0070986) | 5.36753097 |
| 5 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.09150037 |
| 6 | microtubule bundle formation (GO:0001578) | 4.99199160 |
| 7 | regulation of microtubule-based movement (GO:0060632) | 4.98594223 |
| 8 | ventricular system development (GO:0021591) | 4.94844685 |
| 9 | cilium morphogenesis (GO:0060271) | 4.77132652 |
| 10 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.64165354 |
| 11 | neuron cell-cell adhesion (GO:0007158) | 4.62780950 |
| 12 | vitamin transmembrane transport (GO:0035461) | 4.41824265 |
| 13 | synaptic vesicle exocytosis (GO:0016079) | 4.33704416 |
| 14 | cellular component assembly involved in morphogenesis (GO:0010927) | 4.23555500 |
| 15 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.23173141 |
| 16 | vocalization behavior (GO:0071625) | 4.15593995 |
| 17 | locomotory exploration behavior (GO:0035641) | 4.10413152 |
| 18 | glutamate secretion (GO:0014047) | 3.98546914 |
| 19 | synaptic vesicle maturation (GO:0016188) | 3.92016419 |
| 20 | lung epithelium development (GO:0060428) | 3.92001655 |
| 21 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.90738161 |
| 22 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.88513732 |
| 23 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.81713041 |
| 24 | regulation of synaptic vesicle transport (GO:1902803) | 3.79101422 |
| 25 | protein localization to synapse (GO:0035418) | 3.77386158 |
| 26 | centriole assembly (GO:0098534) | 3.74878450 |
| 27 | cell projection assembly (GO:0030031) | 3.72018478 |
| 28 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.68851988 |
| 29 | microtubule-based movement (GO:0007018) | 3.66997644 |
| 30 | primary alcohol catabolic process (GO:0034310) | 3.61157287 |
| 31 | nonmotile primary cilium assembly (GO:0035058) | 3.55593227 |
| 32 | neurotransmitter secretion (GO:0007269) | 3.54293002 |
| 33 | detection of calcium ion (GO:0005513) | 3.51213050 |
| 34 | retinal rod cell development (GO:0046548) | 3.51135559 |
| 35 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.50458708 |
| 36 | smoothened signaling pathway (GO:0007224) | 3.49795177 |
| 37 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.47993243 |
| 38 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.41808129 |
| 39 | postsynaptic membrane organization (GO:0001941) | 3.41089344 |
| 40 | sensory perception of smell (GO:0007608) | 3.40394593 |
| 41 | innervation (GO:0060384) | 3.37598626 |
| 42 | protein localization to cilium (GO:0061512) | 3.35275438 |
| 43 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.34543978 |
| 44 | protein polyglutamylation (GO:0018095) | 3.32936851 |
| 45 | response to xenobiotic stimulus (GO:0009410) | 3.30687455 |
| 46 | retinal cone cell development (GO:0046549) | 3.30500889 |
| 47 | neuronal action potential propagation (GO:0019227) | 3.29974002 |
| 48 | synaptic transmission, glutamatergic (GO:0035249) | 3.29857124 |
| 49 | neuron recognition (GO:0008038) | 3.29403766 |
| 50 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.28309241 |
| 51 | presynaptic membrane assembly (GO:0097105) | 3.27855704 |
| 52 | auditory behavior (GO:0031223) | 3.27029580 |
| 53 | microtubule depolymerization (GO:0007019) | 3.25734055 |
| 54 | activation of protein kinase A activity (GO:0034199) | 3.24867834 |
| 55 | axonal fasciculation (GO:0007413) | 3.23441541 |
| 56 | gamma-aminobutyric acid transport (GO:0015812) | 3.20138163 |
| 57 | sperm motility (GO:0030317) | 3.19608982 |
| 58 | exploration behavior (GO:0035640) | 3.19145850 |
| 59 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.18743018 |
| 60 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.17885014 |
| 61 | cilium movement (GO:0003341) | 3.17711194 |
| 62 | regulation of synapse structural plasticity (GO:0051823) | 3.14131966 |
| 63 | glutamate receptor signaling pathway (GO:0007215) | 3.13360548 |
| 64 | neuron-neuron synaptic transmission (GO:0007270) | 3.13145649 |
| 65 | regulation of vesicle fusion (GO:0031338) | 3.12178025 |
| 66 | response to auditory stimulus (GO:0010996) | 3.10810988 |
| 67 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.09064507 |
| 68 | neuromuscular process controlling posture (GO:0050884) | 3.08849344 |
| 69 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.07468875 |
| 70 | microtubule polymerization or depolymerization (GO:0031109) | 3.07210898 |
| 71 | determination of left/right symmetry (GO:0007368) | 3.07137194 |
| 72 | mechanosensory behavior (GO:0007638) | 3.06956858 |
| 73 | dendritic spine morphogenesis (GO:0060997) | 3.06090069 |
| 74 | regulation of female receptivity (GO:0045924) | 3.06074848 |
| 75 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.05352456 |
| 76 | female mating behavior (GO:0060180) | 3.05304648 |
| 77 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.05254894 |
| 78 | sperm capacitation (GO:0048240) | 3.05115935 |
| 79 | intraciliary transport (GO:0042073) | 3.04902186 |
| 80 | neurotransmitter transport (GO:0006836) | 3.02909130 |
| 81 | centriole replication (GO:0007099) | 3.01852815 |
| 82 | layer formation in cerebral cortex (GO:0021819) | 3.01669929 |
| 83 | ethanol metabolic process (GO:0006067) | 3.01322359 |
| 84 | long-term synaptic potentiation (GO:0060291) | 2.99494649 |
| 85 | behavioral response to cocaine (GO:0048148) | 2.98564036 |
| 86 | diterpenoid biosynthetic process (GO:0016102) | 2.97108669 |
| 87 | establishment of planar polarity (GO:0001736) | 2.93483081 |
| 88 | establishment of tissue polarity (GO:0007164) | 2.93483081 |
| 89 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.92774147 |
| 90 | one-carbon compound transport (GO:0019755) | 2.92453839 |
| 91 | determination of bilateral symmetry (GO:0009855) | 2.92227776 |
| 92 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.92179182 |
| 93 | retinoic acid metabolic process (GO:0042573) | 2.91690388 |
| 94 | transmission of nerve impulse (GO:0019226) | 2.90064748 |
| 95 | membrane depolarization during action potential (GO:0086010) | 2.89487465 |
| 96 | appendage development (GO:0048736) | 2.89240754 |
| 97 | limb development (GO:0060173) | 2.89240754 |
| 98 | mating behavior (GO:0007617) | 2.88401784 |
| 99 | lateral sprouting from an epithelium (GO:0060601) | 2.87422799 |
| 100 | regulation of neurotransmitter secretion (GO:0046928) | 2.86771650 |
| 101 | photoreceptor cell maintenance (GO:0045494) | 2.86701624 |
| 102 | presynaptic membrane organization (GO:0097090) | 2.86104323 |
| 103 | specification of symmetry (GO:0009799) | 2.85423921 |
| 104 | axoneme assembly (GO:0035082) | 2.85396590 |
| 105 | calcium ion-dependent exocytosis (GO:0017156) | 2.85180085 |
| 106 | proline transport (GO:0015824) | 2.85138030 |
| 107 | synapse assembly (GO:0007416) | 2.84781991 |
| 108 | cornea development in camera-type eye (GO:0061303) | 2.84516301 |
| 109 | synaptic vesicle endocytosis (GO:0048488) | 2.84485790 |
| 110 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.82257124 |
| 111 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.82060562 |
| 112 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.80527175 |
| 113 | regulation of neurotransmitter levels (GO:0001505) | 2.78980312 |
| 114 | regulation of synaptic plasticity (GO:0048167) | 2.77460814 |
| 115 | long-term memory (GO:0007616) | 2.77317911 |
| 116 | cytoplasmic microtubule organization (GO:0031122) | 2.76156615 |
| 117 | regulation of postsynaptic membrane potential (GO:0060078) | 2.74665522 |
| 118 | positive regulation of amino acid transport (GO:0051957) | 2.74662141 |
| 119 | positive regulation of membrane potential (GO:0045838) | 2.72706235 |
| 120 | cellular response to glucagon stimulus (GO:0071377) | 2.72257677 |
| 121 | dendrite morphogenesis (GO:0048813) | 2.69056145 |
| 122 | regulation of cilium movement (GO:0003352) | 2.68981798 |
| 123 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.68769133 |
| 124 | behavioral response to nicotine (GO:0035095) | 2.67669111 |
| 125 | regulation of glutamate secretion (GO:0014048) | 2.66852887 |
| 126 | positive regulation of vesicle fusion (GO:0031340) | 2.66784307 |
| 127 | positive regulation of neurotransmitter transport (GO:0051590) | 2.66639648 |
| 128 | lateral ventricle development (GO:0021670) | 2.66529313 |
| 129 | axonemal dynein complex assembly (GO:0070286) | 2.66041808 |
| 130 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.65840082 |
| 131 | regulation of neurotransmitter transport (GO:0051588) | 2.65115868 |
| 132 | striatum development (GO:0021756) | 2.63626893 |
| 133 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.60369732 |
| 134 | multicellular organism reproduction (GO:0032504) | 2.60154675 |
| 135 | neuronal ion channel clustering (GO:0045161) | 2.60139760 |
| 136 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.59953586 |
| 137 | neurotransmitter metabolic process (GO:0042133) | 2.59294079 |
| 138 | positive regulation of exocytosis (GO:0045921) | 2.59152589 |
| 139 | exogenous drug catabolic process (GO:0042738) | 2.56770463 |
| 140 | membrane depolarization (GO:0051899) | 2.56624480 |
| 141 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.56028509 |
| 142 | terpenoid biosynthetic process (GO:0016114) | 2.54409166 |
| 143 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.54267229 |
| 144 | glomerular epithelial cell development (GO:0072310) | 2.53052001 |
| 145 | glutathione derivative metabolic process (GO:1901685) | 2.53022798 |
| 146 | glutathione derivative biosynthetic process (GO:1901687) | 2.53022798 |
| 147 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.52831791 |
| 148 | establishment of monopolar cell polarity (GO:0061162) | 2.52831791 |
| 149 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.51261419 |
| 150 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.50878294 |
| 151 | dopamine receptor signaling pathway (GO:0007212) | 2.50542316 |
| 152 | multi-organism reproductive behavior (GO:0044705) | 2.50086299 |
| 153 | positive regulation of synaptic transmission (GO:0050806) | 2.49990285 |
| 154 | synaptic transmission (GO:0007268) | 2.49703408 |
| 155 | regulation of interleukin-5 production (GO:0032674) | 2.49643304 |
| 156 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.49363937 |
| 157 | negative regulation of axon guidance (GO:1902668) | 2.47711136 |
| 158 | spinal cord motor neuron differentiation (GO:0021522) | 2.47436139 |
| 159 | retinal ganglion cell axon guidance (GO:0031290) | 2.43178128 |
| 160 | neurotransmitter biosynthetic process (GO:0042136) | 2.42989823 |
| 161 | organic cation transport (GO:0015695) | 2.41641818 |
| 162 | aldehyde catabolic process (GO:0046185) | 2.41317750 |
| 163 | rRNA catabolic process (GO:0016075) | 2.41095033 |
| 164 | photoreceptor cell development (GO:0042461) | 2.39084777 |
| 165 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.36668595 |
| 166 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.36011912 |
| 167 | organelle assembly (GO:0070925) | 2.30778783 |
| 168 | tolerance induction (GO:0002507) | 2.30447144 |
| 169 | microtubule-based process (GO:0007017) | 2.30282487 |
| 170 | establishment of apical/basal cell polarity (GO:0035089) | 2.29495205 |
| 171 | neurotransmitter catabolic process (GO:0042135) | 2.28710260 |
| 172 | L-fucose catabolic process (GO:0042355) | 2.28620955 |
| 173 | fucose catabolic process (GO:0019317) | 2.28620955 |
| 174 | L-fucose metabolic process (GO:0042354) | 2.28620955 |
| 175 | regulation of collateral sprouting (GO:0048670) | 2.28302851 |
| 176 | apical protein localization (GO:0045176) | 2.27211649 |
| 177 | eye photoreceptor cell development (GO:0042462) | 2.26716898 |
| 178 | positive regulation of smoothened signaling pathway (GO:0045880) | 2.23356488 |
| 179 | neural tube formation (GO:0001841) | 2.20025088 |
| 180 | regulation of smoothened signaling pathway (GO:0008589) | 2.19848650 |
| 181 | brain morphogenesis (GO:0048854) | 2.19315444 |
| 182 | ethanol oxidation (GO:0006069) | 2.18881032 |
| 183 | retinol metabolic process (GO:0042572) | 2.18312369 |
| 184 | dorsal/ventral pattern formation (GO:0009953) | 2.17878651 |
| 185 | head development (GO:0060322) | 2.15667199 |
| 186 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 11.2922262 |
| 187 | epithelial cilium movement (GO:0003351) | 11.0879660 |
| 188 | motile cilium assembly (GO:0044458) | 10.3610117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.03848098 |
| 2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.37372690 |
| 3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.78641842 |
| 4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.71098079 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.61546031 |
| 6 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.43511882 |
| 7 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.40612495 |
| 8 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.39273716 |
| 9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.38856654 |
| 10 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.38856654 |
| 11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.36413076 |
| 12 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.35385311 |
| 13 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.34301052 |
| 14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.27156674 |
| 15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.25528233 |
| 16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.22322672 |
| 17 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.22085230 |
| 18 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.21959560 |
| 19 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.18862850 |
| 20 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.12887862 |
| 21 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.11485211 |
| 22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.07373292 |
| 23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.98511239 |
| 24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.97043371 |
| 25 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.93039313 |
| 26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.84904040 |
| 27 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.84521673 |
| 28 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.80212261 |
| 29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.74853825 |
| 30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.72365146 |
| 31 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.71199339 |
| 32 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.68334262 |
| 33 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.64678142 |
| 34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.55664016 |
| 35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.54552969 |
| 36 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51967675 |
| 37 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.48380172 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.47519235 |
| 39 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.46936905 |
| 40 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.42442550 |
| 41 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.41181452 |
| 42 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.41052948 |
| 43 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.38779580 |
| 44 | EWS_26573619_Chip-Seq_HEK293_Human | 1.38075356 |
| 45 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.38036731 |
| 46 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.37753651 |
| 47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.37287765 |
| 48 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.36246901 |
| 49 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35870128 |
| 50 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.34017412 |
| 51 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.33717039 |
| 52 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.33265034 |
| 53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.33242494 |
| 54 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.32663324 |
| 55 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.31702553 |
| 56 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30997351 |
| 57 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29865893 |
| 58 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.29294929 |
| 59 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.28689009 |
| 60 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.28205861 |
| 61 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.28205861 |
| 62 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.26423578 |
| 63 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.25310882 |
| 64 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25039721 |
| 65 | STAT3_23295773_ChIP-Seq_U87_Human | 1.24459312 |
| 66 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.22354991 |
| 67 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.20359116 |
| 68 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.18812484 |
| 69 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.18805658 |
| 70 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.18373029 |
| 71 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16890819 |
| 72 | AR_19668381_ChIP-Seq_PC3_Human | 1.16874053 |
| 73 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.16782207 |
| 74 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.16341328 |
| 75 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.14910669 |
| 76 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.14536369 |
| 77 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.14176148 |
| 78 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12892001 |
| 79 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11978191 |
| 80 | TCF4_23295773_ChIP-Seq_U87_Human | 1.11502344 |
| 81 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.10970330 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10455364 |
| 83 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10455364 |
| 84 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.10375607 |
| 85 | AR_25329375_ChIP-Seq_VCAP_Human | 1.09810577 |
| 86 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09299165 |
| 87 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09272791 |
| 88 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.08924164 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08904739 |
| 90 | TP53_16413492_ChIP-PET_HCT116_Human | 1.08017870 |
| 91 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.07667110 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07659704 |
| 93 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.07457979 |
| 94 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.07074218 |
| 95 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07041790 |
| 96 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.04213337 |
| 97 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03209362 |
| 98 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02905401 |
| 99 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02905401 |
| 100 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01242965 |
| 101 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.00844642 |
| 102 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.00730231 |
| 103 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.99769789 |
| 104 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.99483875 |
| 105 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98588650 |
| 106 | VDR_22108803_ChIP-Seq_LS180_Human | 0.98514905 |
| 107 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.98164170 |
| 108 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.97953047 |
| 109 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.97589277 |
| 110 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.95878648 |
| 111 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.95621022 |
| 112 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.94990116 |
| 113 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91985678 |
| 114 | FUS_26573619_Chip-Seq_HEK293_Human | 0.91268083 |
| 115 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90648293 |
| 116 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90032570 |
| 117 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.90032570 |
| 118 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.89371225 |
| 119 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.88559474 |
| 120 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88131670 |
| 121 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.87551640 |
| 122 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.86047902 |
| 123 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.85825905 |
| 124 | KDM2B_26808549_Chip-Seq_REH_Human | 0.85566395 |
| 125 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.84724565 |
| 126 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.84131867 |
| 127 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.83977020 |
| 128 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.82910697 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 4.36512490 |
| 2 | MP0008875_abnormal_xenobiotic_pharmacok | 3.63128407 |
| 3 | MP0003880_abnormal_central_pattern | 3.55629069 |
| 4 | MP0004270_analgesia | 3.42325273 |
| 5 | MP0001984_abnormal_olfaction | 3.25165731 |
| 6 | MP0003635_abnormal_synaptic_transmissio | 3.24756921 |
| 7 | MP0005645_abnormal_hypothalamus_physiol | 2.93234134 |
| 8 | MP0009745_abnormal_behavioral_response | 2.63731452 |
| 9 | MP0002063_abnormal_learning/memory/cond | 2.61009280 |
| 10 | MP0002734_abnormal_mechanical_nocicepti | 2.48556573 |
| 11 | MP0009780_abnormal_chondrocyte_physiolo | 2.47941004 |
| 12 | MP0003122_maternal_imprinting | 2.46115969 |
| 13 | MP0002822_catalepsy | 2.41798079 |
| 14 | MP0002064_seizures | 2.41017900 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.39279850 |
| 16 | MP0002572_abnormal_emotion/affect_behav | 2.37738100 |
| 17 | MP0006276_abnormal_autonomic_nervous | 2.33026064 |
| 18 | MP0002272_abnormal_nervous_system | 2.31374868 |
| 19 | MP0009046_muscle_twitch | 2.27837115 |
| 20 | MP0000566_synostosis | 2.22120144 |
| 21 | MP0001486_abnormal_startle_reflex | 2.20047566 |
| 22 | MP0002102_abnormal_ear_morphology | 2.15236551 |
| 23 | MP0001501_abnormal_sleep_pattern | 2.09134079 |
| 24 | MP0005646_abnormal_pituitary_gland | 2.09127253 |
| 25 | MP0002277_abnormal_respiratory_mucosa | 1.95740419 |
| 26 | MP0002282_abnormal_trachea_morphology | 1.91586400 |
| 27 | MP0002557_abnormal_social/conspecific_i | 1.90185984 |
| 28 | MP0002184_abnormal_innervation | 1.90035631 |
| 29 | MP0003787_abnormal_imprinting | 1.89315293 |
| 30 | MP0002735_abnormal_chemical_nociception | 1.87522207 |
| 31 | MP0002733_abnormal_thermal_nociception | 1.85515648 |
| 32 | MP0005423_abnormal_somatic_nervous | 1.83377971 |
| 33 | MP0002736_abnormal_nociception_after | 1.79421740 |
| 34 | MP0000383_abnormal_hair_follicle | 1.79023861 |
| 35 | MP0002909_abnormal_adrenal_gland | 1.78582594 |
| 36 | MP0002067_abnormal_sensory_capabilities | 1.77935128 |
| 37 | MP0000778_abnormal_nervous_system | 1.74934036 |
| 38 | MP0003879_abnormal_hair_cell | 1.73973753 |
| 39 | MP0001970_abnormal_pain_threshold | 1.70266943 |
| 40 | MP0001502_abnormal_circadian_rhythm | 1.70014442 |
| 41 | MP0001440_abnormal_grooming_behavior | 1.67584182 |
| 42 | MP0000013_abnormal_adipose_tissue | 1.61268970 |
| 43 | MP0006292_abnormal_olfactory_placode | 1.59051531 |
| 44 | MP0005394_taste/olfaction_phenotype | 1.56043431 |
| 45 | MP0005499_abnormal_olfactory_system | 1.56043431 |
| 46 | MP0003011_delayed_dark_adaptation | 1.48524321 |
| 47 | MP0002132_abnormal_respiratory_system | 1.45723425 |
| 48 | MP0004924_abnormal_behavior | 1.38891867 |
| 49 | MP0005386_behavior/neurological_phenoty | 1.38891867 |
| 50 | MP0004811_abnormal_neuron_physiology | 1.38888542 |
| 51 | MP0003195_calcinosis | 1.36010558 |
| 52 | MP0001905_abnormal_dopamine_level | 1.35953273 |
| 53 | MP0001293_anophthalmia | 1.35702813 |
| 54 | MP0001529_abnormal_vocalization | 1.35642121 |
| 55 | MP0001485_abnormal_pinna_reflex | 1.35173673 |
| 56 | MP0000955_abnormal_spinal_cord | 1.34831864 |
| 57 | MP0000049_abnormal_middle_ear | 1.33315033 |
| 58 | MP0002882_abnormal_neuron_morphology | 1.33029939 |
| 59 | MP0004858_abnormal_nervous_system | 1.31922366 |
| 60 | MP0008789_abnormal_olfactory_epithelium | 1.31684731 |
| 61 | MP0002876_abnormal_thyroid_physiology | 1.29696219 |
| 62 | MP0001188_hyperpigmentation | 1.28574514 |
| 63 | MP0010386_abnormal_urinary_bladder | 1.26507508 |
| 64 | MP0002249_abnormal_larynx_morphology | 1.26246813 |
| 65 | MP0010678_abnormal_skin_adnexa | 1.25122191 |
| 66 | MP0005623_abnormal_meninges_morphology | 1.25115832 |
| 67 | MP0005379_endocrine/exocrine_gland_phen | 1.22061272 |
| 68 | MP0000631_abnormal_neuroendocrine_gland | 1.20866558 |
| 69 | MP0008569_lethality_at_weaning | 1.19680470 |
| 70 | MP0006072_abnormal_retinal_apoptosis | 1.18616167 |
| 71 | MP0002234_abnormal_pharynx_morphology | 1.17681267 |
| 72 | MP0003283_abnormal_digestive_organ | 1.16647925 |
| 73 | MP0004043_abnormal_pH_regulation | 1.15398880 |
| 74 | MP0002066_abnormal_motor_capabilities/c | 1.15294442 |
| 75 | MP0004019_abnormal_vitamin_homeostasis | 1.12017163 |
| 76 | MP0005389_reproductive_system_phenotype | 1.10576071 |
| 77 | MP0002653_abnormal_ependyma_morphology | 1.09467644 |
| 78 | MP0003121_genomic_imprinting | 1.09243064 |
| 79 | MP0003329_amyloid_beta_deposits | 1.09150032 |
| 80 | MP0004885_abnormal_endolymph | 1.08842976 |
| 81 | MP0005551_abnormal_eye_electrophysiolog | 1.08379720 |
| 82 | MP0003633_abnormal_nervous_system | 1.06792988 |
| 83 | MP0004142_abnormal_muscle_tone | 1.04389585 |
| 84 | MP0005195_abnormal_posterior_eye | 1.03431850 |
| 85 | MP0000427_abnormal_hair_cycle | 1.02093645 |
| 86 | MP0001324_abnormal_eye_pigmentation | 1.01888298 |
| 87 | MP0003938_abnormal_ear_development | 1.01875808 |
| 88 | MP0001963_abnormal_hearing_physiology | 1.01769093 |
| 89 | MP0002152_abnormal_brain_morphology | 1.01702179 |
| 90 | MP0002233_abnormal_nose_morphology | 1.01687228 |
| 91 | MP0004742_abnormal_vestibular_system | 1.00980008 |
| 92 | MP0001346_abnormal_lacrimal_gland | 0.99438307 |
| 93 | MP0002837_dystrophic_cardiac_calcinosis | 0.98770331 |
| 94 | MP0001944_abnormal_pancreas_morphology | 0.98499259 |
| 95 | MP0002229_neurodegeneration | 0.97311865 |
| 96 | MP0002069_abnormal_eating/drinking_beha | 0.93800032 |
| 97 | MP0003937_abnormal_limbs/digits/tail_de | 0.91481356 |
| 98 | MP0005391_vision/eye_phenotype | 0.91319357 |
| 99 | MP0002638_abnormal_pupillary_reflex | 0.90949440 |
| 100 | MP0003183_abnormal_peptide_metabolism | 0.90901810 |
| 101 | MP0002168_other_aberrant_phenotype | 0.90280065 |
| 102 | MP0002752_abnormal_somatic_nervous | 0.88850254 |
| 103 | MP0003698_abnormal_male_reproductive | 0.88686942 |
| 104 | MP0001929_abnormal_gametogenesis | 0.88678605 |
| 105 | MP0003634_abnormal_glial_cell | 0.86795707 |
| 106 | MP0000751_myopathy | 0.86740164 |
| 107 | MP0005248_abnormal_Harderian_gland | 0.86339931 |
| 108 | MP0004145_abnormal_muscle_electrophysio | 0.86037918 |
| 109 | MP0000003_abnormal_adipose_tissue | 0.85543533 |
| 110 | MP0003631_nervous_system_phenotype | 0.85279187 |
| 111 | MP0003119_abnormal_digestive_system | 0.85265598 |
| 112 | MP0002751_abnormal_autonomic_nervous | 0.84615212 |
| 113 | MP0005535_abnormal_body_temperature | 0.83320460 |
| 114 | MP0001765_abnormal_ion_homeostasis | 0.81764714 |
| 115 | MP0000026_abnormal_inner_ear | 0.81371955 |
| 116 | MP0010030_abnormal_orbit_morphology | 0.80645441 |
| 117 | MP0003136_yellow_coat_color | 0.79746587 |
| 118 | MP0004133_heterotaxia | 0.79553259 |
| 119 | MP0000613_abnormal_salivary_gland | 0.78794700 |
| 120 | MP0001177_atelectasis | 0.78641849 |
| 121 | MP0008877_abnormal_DNA_methylation | 0.77812228 |
| 122 | MP0001270_distended_abdomen | 0.77292078 |
| 123 | MP0002160_abnormal_reproductive_system | 0.77269305 |
| 124 | MP0003942_abnormal_urinary_system | 0.77174991 |
| 125 | MP0005187_abnormal_penis_morphology | 0.76051320 |
| 126 | MP0005377_hearing/vestibular/ear_phenot | 0.74769471 |
| 127 | MP0003878_abnormal_ear_physiology | 0.74769471 |
| 128 | MP0005395_other_phenotype | 0.74707474 |
| 129 | MP0002928_abnormal_bile_duct | 0.71359670 |
| 130 | MP0001299_abnormal_eye_distance/ | 0.70450117 |
| 131 | MP0004085_abnormal_heartbeat | 0.70190401 |
| 132 | MP0005253_abnormal_eye_physiology | 0.70162015 |
| 133 | MP0002693_abnormal_pancreas_physiology | 0.69489758 |
| 134 | MP0003953_abnormal_hormone_level | 0.66925825 |
| 135 | MP0001664_abnormal_digestion | 0.65675214 |
| 136 | MP0008872_abnormal_physiological_respon | 0.60782423 |
| 137 | MP0002078_abnormal_glucose_homeostasis | 0.60304414 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bronchiectasis (HP:0002110) | 5.61007105 |
| 2 | Focal motor seizures (HP:0011153) | 5.08403278 |
| 3 | Nasal polyposis (HP:0100582) | 4.80955716 |
| 4 | Abnormal ciliary motility (HP:0012262) | 4.31502616 |
| 5 | Pancreatic cysts (HP:0001737) | 4.22128284 |
| 6 | Abnormal respiratory motile cilium physiology (HP:0012261) | 4.12954467 |
| 7 | Atonic seizures (HP:0010819) | 4.12928847 |
| 8 | Myokymia (HP:0002411) | 4.09216912 |
| 9 | Focal seizures (HP:0007359) | 4.09140119 |
| 10 | Visual hallucinations (HP:0002367) | 3.90793189 |
| 11 | Abnormality of the nasal mucosa (HP:0000433) | 3.83263218 |
| 12 | Epileptic encephalopathy (HP:0200134) | 3.70204358 |
| 13 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.59054925 |
| 14 | Febrile seizures (HP:0002373) | 3.55560084 |
| 15 | Chronic hepatic failure (HP:0100626) | 3.43417904 |
| 16 | Absence seizures (HP:0002121) | 3.42466401 |
| 17 | Abnormality of the renal medulla (HP:0100957) | 3.28248196 |
| 18 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.23031543 |
| 19 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.23031543 |
| 20 | Progressive cerebellar ataxia (HP:0002073) | 3.18891144 |
| 21 | Rhinitis (HP:0012384) | 3.17287655 |
| 22 | Postaxial foot polydactyly (HP:0001830) | 3.13845312 |
| 23 | Medial flaring of the eyebrow (HP:0010747) | 3.13277227 |
| 24 | Recurrent sinusitis (HP:0011108) | 3.07721863 |
| 25 | Chronic sinusitis (HP:0011109) | 3.05911895 |
| 26 | Bronchitis (HP:0012387) | 3.03513427 |
| 27 | Absent/shortened dynein arms (HP:0200106) | 3.01008644 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.01008644 |
| 29 | Hyperventilation (HP:0002883) | 3.00849273 |
| 30 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.98935697 |
| 31 | Dialeptic seizures (HP:0011146) | 2.95315465 |
| 32 | Generalized tonic-clonic seizures (HP:0002069) | 2.95151958 |
| 33 | Gait imbalance (HP:0002141) | 2.84577072 |
| 34 | Limb dystonia (HP:0002451) | 2.84255171 |
| 35 | Hypothermia (HP:0002045) | 2.82926519 |
| 36 | Agitation (HP:0000713) | 2.80775122 |
| 37 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.75468701 |
| 38 | Male infertility (HP:0003251) | 2.69311219 |
| 39 | Genetic anticipation (HP:0003743) | 2.67845207 |
| 40 | Absent eyebrow (HP:0002223) | 2.66458429 |
| 41 | Pheochromocytoma (HP:0002666) | 2.60805973 |
| 42 | Congenital primary aphakia (HP:0007707) | 2.60230316 |
| 43 | Tubular atrophy (HP:0000092) | 2.57730966 |
| 44 | Anencephaly (HP:0002323) | 2.56140448 |
| 45 | Action tremor (HP:0002345) | 2.51868342 |
| 46 | Sclerocornea (HP:0000647) | 2.48298271 |
| 47 | Median cleft lip (HP:0000161) | 2.47364360 |
| 48 | Chronic bronchitis (HP:0004469) | 2.46983159 |
| 49 | Recurrent otitis media (HP:0000403) | 2.46531156 |
| 50 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.45390067 |
| 51 | Ankle clonus (HP:0011448) | 2.44233823 |
| 52 | Tubulointerstitial nephritis (HP:0001970) | 2.44154087 |
| 53 | Supranuclear gaze palsy (HP:0000605) | 2.43601749 |
| 54 | Pancreatic fibrosis (HP:0100732) | 2.42791943 |
| 55 | Nephrogenic diabetes insipidus (HP:0009806) | 2.41655061 |
| 56 | Male pseudohermaphroditism (HP:0000037) | 2.39630068 |
| 57 | Occipital encephalocele (HP:0002085) | 2.39475568 |
| 58 | Abnormal eating behavior (HP:0100738) | 2.38028845 |
| 59 | Amblyopia (HP:0000646) | 2.37912696 |
| 60 | Anxiety (HP:0000739) | 2.36170878 |
| 61 | Decreased circulating renin level (HP:0003351) | 2.34323854 |
| 62 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.33879663 |
| 63 | True hermaphroditism (HP:0010459) | 2.32658963 |
| 64 | Genital tract atresia (HP:0001827) | 2.31159963 |
| 65 | Failure to thrive in infancy (HP:0001531) | 2.30076042 |
| 66 | Epileptiform EEG discharges (HP:0011182) | 2.29643185 |
| 67 | Nephronophthisis (HP:0000090) | 2.27727074 |
| 68 | EEG with generalized epileptiform discharges (HP:0011198) | 2.26122092 |
| 69 | Vaginal atresia (HP:0000148) | 2.25317671 |
| 70 | Hyperactive renin-angiotensin system (HP:0000841) | 2.23696388 |
| 71 | Depression (HP:0000716) | 2.22867636 |
| 72 | Abnormal hair whorl (HP:0010721) | 2.22325218 |
| 73 | Torticollis (HP:0000473) | 2.22158381 |
| 74 | Abnormality of the renal cortex (HP:0011035) | 2.20629116 |
| 75 | Abnormality of midbrain morphology (HP:0002418) | 2.19831038 |
| 76 | Molar tooth sign on MRI (HP:0002419) | 2.19831038 |
| 77 | Furrowed tongue (HP:0000221) | 2.19319166 |
| 78 | Atelectasis (HP:0100750) | 2.19133940 |
| 79 | Hemiparesis (HP:0001269) | 2.15782056 |
| 80 | Hypsarrhythmia (HP:0002521) | 2.14569725 |
| 81 | Truncal ataxia (HP:0002078) | 2.12643923 |
| 82 | Asplenia (HP:0001746) | 2.12604085 |
| 83 | Neuroendocrine neoplasm (HP:0100634) | 2.10024862 |
| 84 | Hypoventilation (HP:0002791) | 2.08102988 |
| 85 | Abnormal drinking behavior (HP:0030082) | 2.07134591 |
| 86 | Polydipsia (HP:0001959) | 2.07134591 |
| 87 | Focal dystonia (HP:0004373) | 2.04819099 |
| 88 | Anosmia (HP:0000458) | 2.00483186 |
| 89 | Preaxial hand polydactyly (HP:0001177) | 2.00202511 |
| 90 | Polyphagia (HP:0002591) | 1.99390576 |
| 91 | Gaze-evoked nystagmus (HP:0000640) | 1.99339846 |
| 92 | Labial hypoplasia (HP:0000066) | 1.99238972 |
| 93 | Chronic otitis media (HP:0000389) | 1.98002821 |
| 94 | Broad-based gait (HP:0002136) | 1.97160282 |
| 95 | Oculomotor apraxia (HP:0000657) | 1.97042733 |
| 96 | Craniofacial dystonia (HP:0012179) | 1.93428958 |
| 97 | Dysdiadochokinesis (HP:0002075) | 1.92978478 |
| 98 | Poor coordination (HP:0002370) | 1.92535656 |
| 99 | Absent eyelashes (HP:0000561) | 1.91307818 |
| 100 | Retinal dysplasia (HP:0007973) | 1.90770783 |
| 101 | Abnormality of the dental pulp (HP:0006479) | 1.90024497 |
| 102 | Spastic gait (HP:0002064) | 1.89020975 |
| 103 | Specific learning disability (HP:0001328) | 1.88929782 |
| 104 | Tubulointerstitial abnormality (HP:0001969) | 1.88782217 |
| 105 | Blue irides (HP:0000635) | 1.86268917 |
| 106 | Abnormality of the dental root (HP:0006486) | 1.85546687 |
| 107 | Taurodontia (HP:0000679) | 1.85546687 |
| 108 | Abnormality of permanent molar morphology (HP:0011071) | 1.85546687 |
| 109 | Megalencephaly (HP:0001355) | 1.85105734 |
| 110 | Hip dysplasia (HP:0001385) | 1.84034296 |
| 111 | Neurofibrillary tangles (HP:0002185) | 1.83073873 |
| 112 | Cystic liver disease (HP:0006706) | 1.81713633 |
| 113 | Postaxial hand polydactyly (HP:0001162) | 1.81653837 |
| 114 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.81087387 |
| 115 | Facial cleft (HP:0002006) | 1.80186841 |
| 116 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.80011001 |
| 117 | Abnormal biliary tract physiology (HP:0012439) | 1.79764336 |
| 118 | Bile duct proliferation (HP:0001408) | 1.79764336 |
| 119 | Dysmetria (HP:0001310) | 1.79006815 |
| 120 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.78431022 |
| 121 | Infertility (HP:0000789) | 1.77370323 |
| 122 | Excessive salivation (HP:0003781) | 1.77112330 |
| 123 | Drooling (HP:0002307) | 1.77112330 |
| 124 | Cerebral inclusion bodies (HP:0100314) | 1.73675306 |
| 125 | Congenital hepatic fibrosis (HP:0002612) | 1.72061350 |
| 126 | Abnormality of molar (HP:0011077) | 1.70931730 |
| 127 | Abnormality of molar morphology (HP:0011070) | 1.70931730 |
| 128 | Hypoglycemic seizures (HP:0002173) | 1.70699761 |
| 129 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.69893862 |
| 130 | Hyperthyroidism (HP:0000836) | 1.69517471 |
| 131 | Renal salt wasting (HP:0000127) | 1.69098789 |
| 132 | Abnormality of dentin (HP:0010299) | 1.67232834 |
| 133 | Narrow nasal bridge (HP:0000446) | 1.67115724 |
| 134 | Hypoplastic female external genitalia (HP:0012815) | 1.67061179 |
| 135 | Decreased central vision (HP:0007663) | 1.66684171 |
| 136 | Stage 5 chronic kidney disease (HP:0003774) | 1.64188883 |
| 137 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.64075785 |
| 138 | Tubulointerstitial fibrosis (HP:0005576) | 1.60268749 |
| 139 | Anophthalmia (HP:0000528) | 1.59210828 |
| 140 | Nephropathy (HP:0000112) | 1.58770208 |
| 141 | Narrow forehead (HP:0000341) | 1.58344375 |
| 142 | Large for gestational age (HP:0001520) | 1.56499871 |
| 143 | Type II lissencephaly (HP:0007260) | 1.53292564 |
| 144 | Abnormality of renin-angiotensin system (HP:0000847) | 1.50532782 |
| 145 | Polyuria (HP:0000103) | 1.50472336 |
| 146 | Retinitis pigmentosa (HP:0000510) | 1.46032087 |
| 147 | Supernumerary spleens (HP:0009799) | 1.44859660 |
| 148 | Aganglionic megacolon (HP:0002251) | 1.43856768 |
| 149 | Multicystic kidney dysplasia (HP:0000003) | 1.40312235 |
| 150 | Bell-shaped thorax (HP:0001591) | 1.40120253 |
| 151 | Renal dysplasia (HP:0000110) | 1.38852270 |
| 152 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.38162058 |
| 153 | Prominent nasal bridge (HP:0000426) | 1.37686383 |
| 154 | Hyperaldosteronism (HP:0000859) | 1.36642392 |
| 155 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.33700387 |
| 156 | Disproportionate short-trunk short stature (HP:0003521) | 1.33661950 |
| 157 | Abolished electroretinogram (ERG) (HP:0000550) | 1.32977182 |
| 158 | Hypoplasia of the uterus (HP:0000013) | 1.32184299 |
| 159 | Broad foot (HP:0001769) | 1.31843440 |
| 160 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.31483341 |
| 161 | Holoprosencephaly (HP:0001360) | 1.25156628 |
| 162 | Abnormality of macular pigmentation (HP:0008002) | 1.24610971 |
| 163 | Congenital stationary night blindness (HP:0007642) | 1.23581725 |
| 164 | Short femoral neck (HP:0100864) | 1.23477348 |
| 165 | Highly arched eyebrow (HP:0002553) | 1.21376375 |
| 166 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.21005207 |
| 167 | Bifid scrotum (HP:0000048) | 1.20811861 |
| 168 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.20246582 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NTRK3 | 3.78499984 |
| 2 | MST4 | 3.34405998 |
| 3 | EPHA4 | 3.13861973 |
| 4 | CASK | 2.97035693 |
| 5 | MAP3K2 | 2.93584632 |
| 6 | MAP3K4 | 2.62280928 |
| 7 | ERBB3 | 2.56305061 |
| 8 | MAP2K7 | 2.46059417 |
| 9 | TNIK | 2.46052872 |
| 10 | MAPK15 | 2.42601113 |
| 11 | BMPR2 | 2.41739964 |
| 12 | NTRK2 | 2.39821458 |
| 13 | MARK1 | 2.30502792 |
| 14 | EPHA2 | 2.26849710 |
| 15 | MINK1 | 2.19473772 |
| 16 | DAPK2 | 2.16741617 |
| 17 | MAP3K9 | 2.04548417 |
| 18 | MAP3K12 | 2.04085223 |
| 19 | GRK1 | 2.00250539 |
| 20 | NTRK1 | 1.99439158 |
| 21 | PRKD3 | 1.98633546 |
| 22 | MAP4K2 | 1.97327987 |
| 23 | PINK1 | 1.95776501 |
| 24 | TLK1 | 1.94719722 |
| 25 | NME1 | 1.88106778 |
| 26 | INSRR | 1.81103827 |
| 27 | ADRBK2 | 1.80052812 |
| 28 | MAPK13 | 1.69933597 |
| 29 | MAP2K4 | 1.68436026 |
| 30 | PHKG1 | 1.65574506 |
| 31 | PHKG2 | 1.65574506 |
| 32 | PNCK | 1.64549234 |
| 33 | FRK | 1.55372581 |
| 34 | TAOK3 | 1.48409591 |
| 35 | EPHB2 | 1.40694546 |
| 36 | STK38L | 1.40512239 |
| 37 | EPHA3 | 1.40326231 |
| 38 | PRPF4B | 1.38432787 |
| 39 | PAK6 | 1.37525985 |
| 40 | ARAF | 1.36614944 |
| 41 | PLK2 | 1.32632786 |
| 42 | UHMK1 | 1.29505715 |
| 43 | PRKCG | 1.28739354 |
| 44 | CDK5 | 1.26253309 |
| 45 | DAPK1 | 1.24994061 |
| 46 | NEK1 | 1.23332241 |
| 47 | SIK3 | 1.21477197 |
| 48 | SIK2 | 1.19319909 |
| 49 | SGK223 | 1.16261517 |
| 50 | SGK494 | 1.16261517 |
| 51 | WNK3 | 1.15722735 |
| 52 | SGK2 | 1.15024232 |
| 53 | PAK3 | 1.14829747 |
| 54 | MAP3K3 | 1.12448112 |
| 55 | KSR1 | 1.10106747 |
| 56 | STK39 | 1.09519023 |
| 57 | LIMK1 | 1.08626286 |
| 58 | CAMKK1 | 1.08370650 |
| 59 | GRK5 | 1.06722625 |
| 60 | BMPR1B | 1.06664564 |
| 61 | TRIM28 | 1.04590484 |
| 62 | NEK6 | 0.98652915 |
| 63 | MAPKAPK3 | 0.97846105 |
| 64 | CAMK2B | 0.97193384 |
| 65 | DYRK2 | 0.95093368 |
| 66 | CAMK2A | 0.93899277 |
| 67 | CAMKK2 | 0.92087640 |
| 68 | RIPK4 | 0.91491435 |
| 69 | PRKCI | 0.89341801 |
| 70 | AKT3 | 0.88245959 |
| 71 | CAMK2D | 0.85609946 |
| 72 | STK38 | 0.83842812 |
| 73 | RIPK1 | 0.79704730 |
| 74 | BRAF | 0.79523294 |
| 75 | PRKCH | 0.79350443 |
| 76 | TIE1 | 0.79287282 |
| 77 | EPHB1 | 0.79022813 |
| 78 | WNK4 | 0.75996069 |
| 79 | KSR2 | 0.75524620 |
| 80 | FER | 0.75028464 |
| 81 | CAMK2G | 0.73842434 |
| 82 | PRKCE | 0.73273213 |
| 83 | CSNK1G1 | 0.72904183 |
| 84 | CDC42BPA | 0.71169721 |
| 85 | FGFR2 | 0.70747592 |
| 86 | RPS6KA2 | 0.70728088 |
| 87 | SGK3 | 0.70559373 |
| 88 | CSNK1G2 | 0.70332781 |
| 89 | DYRK1A | 0.69223207 |
| 90 | PLK4 | 0.68013010 |
| 91 | LMTK2 | 0.65656379 |
| 92 | CDK19 | 0.65517109 |
| 93 | BCR | 0.65374180 |
| 94 | PTK2B | 0.63051889 |
| 95 | ERBB2 | 0.57515047 |
| 96 | ROCK2 | 0.57025603 |
| 97 | HIPK2 | 0.55387330 |
| 98 | TYRO3 | 0.53817258 |
| 99 | CDK14 | 0.53458835 |
| 100 | SGK1 | 0.51811195 |
| 101 | CDK18 | 0.51201487 |
| 102 | CAMK1G | 0.51111723 |
| 103 | PRKCZ | 0.50388112 |
| 104 | BRSK2 | 0.50360754 |
| 105 | FES | 0.50043610 |
| 106 | WNK1 | 0.49094846 |
| 107 | CAMK1 | 0.48382464 |
| 108 | STK11 | 0.47700811 |
| 109 | PKN1 | 0.47645826 |
| 110 | AURKA | 0.47524673 |
| 111 | PIK3CG | 0.47514576 |
| 112 | RET | 0.47501986 |
| 113 | DYRK1B | 0.47408132 |
| 114 | RPS6KB1 | 0.47311227 |
| 115 | STK24 | 0.46669723 |
| 116 | MAP3K1 | 0.45872022 |
| 117 | MET | 0.44489841 |
| 118 | CDK15 | 0.44371369 |
| 119 | GRK7 | 0.43620339 |
| 120 | WEE1 | 0.43278391 |
| 121 | MAP3K7 | 0.43199521 |
| 122 | MARK2 | 0.42973189 |
| 123 | BCKDK | 0.42218097 |
| 124 | ROCK1 | 0.41186541 |
| 125 | ACVR1B | 0.41180850 |
| 126 | OXSR1 | 0.39876483 |
| 127 | PRKD2 | 0.39394079 |
| 128 | PLK1 | 0.39227494 |
| 129 | CSNK1G3 | 0.38778928 |
| 130 | ADRBK1 | 0.37513812 |
| 131 | RPS6KA3 | 0.36692558 |
| 132 | CSNK1A1 | 0.35528875 |
| 133 | CDK3 | 0.35019841 |
| 134 | CSNK1A1L | 0.34775496 |
| 135 | TNK2 | 0.34661134 |
| 136 | CDK11A | 0.34653285 |
| 137 | MAPKAPK5 | 0.34313908 |
| 138 | MAPK10 | 0.34087626 |
| 139 | MAP2K1 | 0.33943093 |
| 140 | TSSK6 | 0.33162673 |
| 141 | PRKACA | 0.32933994 |
| 142 | TESK1 | 0.32217087 |
| 143 | NEK2 | 0.31296455 |
| 144 | NLK | 0.31230990 |
| 145 | IRAK1 | 0.29880786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 3.74424593 |
| 2 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 3.06940792 |
| 3 | Nicotine addiction_Homo sapiens_hsa05033 | 3.05917288 |
| 4 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.98510894 |
| 5 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.66055107 |
| 6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.66041424 |
| 7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.59818829 |
| 8 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.58594459 |
| 9 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.55733322 |
| 10 | Insulin secretion_Homo sapiens_hsa04911 | 2.54134243 |
| 11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.40918415 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.38202201 |
| 13 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.36413003 |
| 14 | Morphine addiction_Homo sapiens_hsa05032 | 2.32927026 |
| 15 | Histidine metabolism_Homo sapiens_hsa00340 | 2.29264965 |
| 16 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.29007843 |
| 17 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.28678528 |
| 18 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.25568101 |
| 19 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.23782297 |
| 20 | Long-term potentiation_Homo sapiens_hsa04720 | 2.21185835 |
| 21 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.15914526 |
| 22 | Cocaine addiction_Homo sapiens_hsa05030 | 2.11568619 |
| 23 | Taste transduction_Homo sapiens_hsa04742 | 2.10491192 |
| 24 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.09428647 |
| 25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.89590420 |
| 26 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.87967994 |
| 27 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.85116913 |
| 28 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.83246920 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.81434822 |
| 30 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.80971726 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.79694334 |
| 32 | Salivary secretion_Homo sapiens_hsa04970 | 1.72614667 |
| 33 | Renin secretion_Homo sapiens_hsa04924 | 1.65767547 |
| 34 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.60410796 |
| 35 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.53009094 |
| 36 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.51360680 |
| 37 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.48093654 |
| 38 | Retinol metabolism_Homo sapiens_hsa00830 | 1.45772517 |
| 39 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.41877492 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38576527 |
| 41 | Long-term depression_Homo sapiens_hsa04730 | 1.37910447 |
| 42 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.36963228 |
| 43 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.33006485 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 1.32477571 |
| 45 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.31502387 |
| 46 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.23357530 |
| 47 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.22274713 |
| 48 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.18286480 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.18058286 |
| 50 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.17406525 |
| 51 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.14687433 |
| 52 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.13985400 |
| 53 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.13934483 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.12806791 |
| 55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.12153571 |
| 56 | Gap junction_Homo sapiens_hsa04540 | 1.09143312 |
| 57 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.08908260 |
| 58 | Melanogenesis_Homo sapiens_hsa04916 | 1.07176491 |
| 59 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06761332 |
| 60 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.06576003 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 1.05034252 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03787396 |
| 63 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.03727605 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.03207990 |
| 65 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.02963108 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.01409180 |
| 67 | ABC transporters_Homo sapiens_hsa02010 | 0.97067185 |
| 68 | Basal transcription factors_Homo sapiens_hsa03022 | 0.96673050 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.96283180 |
| 70 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.94417965 |
| 71 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.94393030 |
| 72 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.92671137 |
| 73 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.92517165 |
| 74 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.91790286 |
| 75 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.88130319 |
| 76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.87412323 |
| 77 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.86910356 |
| 78 | Axon guidance_Homo sapiens_hsa04360 | 0.86828488 |
| 79 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.84611341 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.82681137 |
| 81 | Prion diseases_Homo sapiens_hsa05020 | 0.79813879 |
| 82 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.77410579 |
| 83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.76554044 |
| 84 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74783367 |
| 85 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.74234215 |
| 86 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.72621968 |
| 87 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.72393842 |
| 88 | Glioma_Homo sapiens_hsa05214 | 0.72347960 |
| 89 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.72249104 |
| 90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.70882885 |
| 91 | Tight junction_Homo sapiens_hsa04530 | 0.70585255 |
| 92 | Bile secretion_Homo sapiens_hsa04976 | 0.65184267 |
| 93 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.64863146 |
| 94 | Alzheimers disease_Homo sapiens_hsa05010 | 0.64795964 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.64657494 |
| 96 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64047109 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.63808776 |
| 98 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.63535085 |
| 99 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.62983286 |
| 100 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.60925827 |
| 101 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.60815513 |
| 102 | Circadian rhythm_Homo sapiens_hsa04710 | 0.59309332 |
| 103 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.56948386 |
| 104 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.55078781 |
| 105 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.54959273 |
| 106 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.53903320 |
| 107 | Parkinsons disease_Homo sapiens_hsa05012 | 0.50987719 |
| 108 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.50504322 |
| 109 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.49405124 |
| 110 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.47779683 |
| 111 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47564638 |
| 112 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.47262574 |
| 113 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.46467856 |
| 114 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45286826 |
| 115 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45187839 |
| 116 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.44695751 |
| 117 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.43951318 |
| 118 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.43533865 |
| 119 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43438342 |
| 120 | Huntingtons disease_Homo sapiens_hsa05016 | 0.43393574 |
| 121 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.42670465 |
| 122 | RNA polymerase_Homo sapiens_hsa03020 | 0.41323413 |
| 123 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.40732167 |
| 124 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.39034977 |
| 125 | Purine metabolism_Homo sapiens_hsa00230 | 0.37119301 |
| 126 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.35618831 |
| 127 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.34869246 |
| 128 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34518500 |
| 129 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.34469651 |
| 130 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.34343710 |
| 131 | RNA degradation_Homo sapiens_hsa03018 | 0.34005381 |
| 132 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.33997071 |
| 133 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.33511072 |
| 134 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.31439686 |
| 135 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.30910163 |
| 136 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30317343 |
| 137 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.30153557 |
| 138 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.29133109 |
| 139 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27151663 |
| 140 | Endometrial cancer_Homo sapiens_hsa05213 | 0.26707015 |
| 141 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.26424412 |
| 142 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.25764249 |
| 143 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.25170716 |
| 144 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.22106861 |
| 145 | Protein export_Homo sapiens_hsa03060 | 0.22009701 |
| 146 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.20356891 |
| 147 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.19566973 |
| 148 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.19489656 |

