RAB3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.40454010
2energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)4.99316126
3ATP hydrolysis coupled proton transport (GO:0015991)4.99316126
4behavioral response to ethanol (GO:0048149)4.92979477
5transferrin transport (GO:0033572)4.88507927
6phenol-containing compound catabolic process (GO:0019336)4.76107018
7neurotransmitter secretion (GO:0007269)4.61430156
8trivalent inorganic cation transport (GO:0072512)4.56293954
9ferric iron transport (GO:0015682)4.56293954
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.54677583
11regulation of synaptic vesicle exocytosis (GO:2000300)4.42563951
12NADH metabolic process (GO:0006734)4.29905221
13vocalization behavior (GO:0071625)4.27475206
14regulation of short-term neuronal synaptic plasticity (GO:0048172)4.26835390
15neuron cell-cell adhesion (GO:0007158)4.19714216
16regulation of type B pancreatic cell apoptotic process (GO:2000674)4.11969781
17glutamate secretion (GO:0014047)4.11619144
18regulation of glutamate receptor signaling pathway (GO:1900449)4.10815963
19succinate metabolic process (GO:0006105)4.10549418
20behavioral response to nicotine (GO:0035095)4.07776623
21neuronal action potential propagation (GO:0019227)3.94151960
22positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.91952403
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.87988840
24regulation of synaptic vesicle transport (GO:1902803)3.85567878
25regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.84564436
26negative regulation of synaptic transmission, GABAergic (GO:0032229)3.82604011
27membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.80254152
28phagosome maturation (GO:0090382)3.80213976
29synaptic vesicle docking involved in exocytosis (GO:0016081)3.79035584
30proline transport (GO:0015824)3.77066908
31neuron-neuron synaptic transmission (GO:0007270)3.71807343
32neurotransmitter transport (GO:0006836)3.71541974
33negative regulation of hormone biosynthetic process (GO:0032353)3.70555836
34nodal signaling pathway (GO:0038092)3.67210321
35oxaloacetate metabolic process (GO:0006107)3.67112132
36neurotransmitter biosynthetic process (GO:0042136)3.64218208
37protein localization to synapse (GO:0035418)3.59000448
38neurotransmitter catabolic process (GO:0042135)3.52866819
39gamma-aminobutyric acid transport (GO:0015812)3.52800234
40detection of calcium ion (GO:0005513)3.50234652
41synaptic vesicle maturation (GO:0016188)3.45753230
42glycerophospholipid catabolic process (GO:0046475)3.44120427
43regulation of neurotransmitter levels (GO:0001505)3.42773426
44positive regulation of action potential (GO:0045760)3.42245281
45adult feeding behavior (GO:0008343)3.40995204
46positive regulation of amino acid transport (GO:0051957)3.39580441
47positive regulation of synaptic transmission, GABAergic (GO:0032230)3.39327837
48chaperone-mediated protein transport (GO:0072321)3.38728725
49positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.38672383
50inner ear receptor cell development (GO:0060119)3.37954325
51synaptic transmission, glutamatergic (GO:0035249)3.36905788
52insulin secretion (GO:0030073)3.35487139
53regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.33158536
54neuromuscular process controlling posture (GO:0050884)3.31153037
55catecholamine transport (GO:0051937)3.30504581
56mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.30272171
57aggressive behavior (GO:0002118)3.28658345
58neurotransmitter-gated ion channel clustering (GO:0072578)3.26468558
59striatum development (GO:0021756)3.26278110
60synaptic transmission, dopaminergic (GO:0001963)3.23123059
61ionotropic glutamate receptor signaling pathway (GO:0035235)3.21601370
62regulation of neurotransmitter secretion (GO:0046928)3.18046133
63regulation of vesicle fusion (GO:0031338)3.13111337
64positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.12119495
65activation of protein kinase A activity (GO:0034199)3.11107503
66electron transport chain (GO:0022900)3.10709208
67water-soluble vitamin biosynthetic process (GO:0042364)3.10395088
68cullin deneddylation (GO:0010388)3.10278247
69protein complex biogenesis (GO:0070271)3.09963901
70female mating behavior (GO:0060180)3.09512631
71sympathetic nervous system development (GO:0048485)3.09050187
72positive regulation of protein autophosphorylation (GO:0031954)3.08171795
73ATP synthesis coupled proton transport (GO:0015986)3.07679490
74energy coupled proton transport, down electrochemical gradient (GO:0015985)3.07679490
75tricarboxylic acid cycle (GO:0006099)3.07491812
76protein localization to cilium (GO:0061512)3.07257969
77synaptic transmission (GO:0007268)3.07190155
78protein neddylation (GO:0045116)3.06033687
79neuromuscular synaptic transmission (GO:0007274)3.05871445
80respiratory electron transport chain (GO:0022904)3.05837882
81sequestering of extracellular ligand from receptor (GO:0035581)3.05094375
82regulation of synaptic transmission, GABAergic (GO:0032228)3.03529598
83endocrine pancreas development (GO:0031018)3.03272707
84cell migration in hindbrain (GO:0021535)3.02276408
85negative regulation of hormone metabolic process (GO:0032351)3.01303226
86maternal behavior (GO:0042711)3.01141559
87negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.99980669
88negative regulation of cytosolic calcium ion concentration (GO:0051481)2.98988109
89cellular ketone body metabolic process (GO:0046950)2.98980567
90negative regulation of microtubule polymerization (GO:0031115)2.98553053
91* regulation of neurotransmitter transport (GO:0051588)2.97820175
92long-term synaptic potentiation (GO:0060291)2.97068115
93regulation of response to food (GO:0032095)2.96320716
94negative regulation of activin receptor signaling pathway (GO:0032926)2.95666195
95presynaptic membrane assembly (GO:0097105)2.94975480
96postsynaptic membrane organization (GO:0001941)2.93958000
97positive regulation of mitochondrial fission (GO:0090141)2.93591017
98gamma-aminobutyric acid signaling pathway (GO:0007214)2.91543379
99regulation of protein kinase A signaling (GO:0010738)2.91429419
100signal peptide processing (GO:0006465)2.90720214
101kidney morphogenesis (GO:0060993)2.88972240
102neurotransmitter metabolic process (GO:0042133)2.88190059
103multicellular organismal reproductive behavior (GO:0033057)2.85099878
104protein-cofactor linkage (GO:0018065)2.84497306
105dendritic spine morphogenesis (GO:0060997)2.83664531
106glutamate receptor signaling pathway (GO:0007215)2.83380494
107startle response (GO:0001964)2.80834592
108adult behavior (GO:0030534)2.80780585
109regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.80356728
110cerebellar Purkinje cell differentiation (GO:0021702)2.79004529
111neuron recognition (GO:0008038)2.78103178
112regulation of synapse structural plasticity (GO:0051823)2.78101423
113presynaptic membrane organization (GO:0097090)2.78075892
114negative regulation of axon extension involved in axon guidance (GO:0048843)2.77603064
115regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.76942114
116negative regulation of dendrite morphogenesis (GO:0050774)2.76140608
117positive regulation of synapse assembly (GO:0051965)2.75996669
118regulation of hexokinase activity (GO:1903299)2.75756825
119regulation of glucokinase activity (GO:0033131)2.75756825
120response to cocaine (GO:0042220)2.74804571
121establishment of synaptic vesicle localization (GO:0097480)2.73807318
122calcium ion import (GO:0070509)2.71384994
123female gonad development (GO:0008585)2.66554994
124lactate metabolic process (GO:0006089)2.63652169
125activin receptor signaling pathway (GO:0032924)2.60661323
126peptide hormone processing (GO:0016486)2.60303187
127inositol phosphate catabolic process (GO:0071545)2.58178599
128ketone body metabolic process (GO:1902224)2.57861168
129somite rostral/caudal axis specification (GO:0032525)2.56582124
130negative regulation of axon guidance (GO:1902668)2.53968663
131nephron tubule morphogenesis (GO:0072078)2.52527132
132nephron epithelium morphogenesis (GO:0072088)2.52527132
133renal tubule morphogenesis (GO:0061333)2.51570544
134L-alpha-amino acid transmembrane transport (GO:1902475)2.48629362
135positive regulation of meiosis (GO:0045836)2.47832555
136artery development (GO:0060840)2.46396773
137type B pancreatic cell development (GO:0003323)2.45222417
138cellular response to vitamin D (GO:0071305)2.42595253
139positive regulation of glycolytic process (GO:0045821)2.41197277
140establishment of protein localization to Golgi (GO:0072600)2.38937510
141UDP-N-acetylglucosamine metabolic process (GO:0006047)2.38299762
142smooth muscle tissue development (GO:0048745)2.37878950
143innervation (GO:0060384)2.34979662
144peptide hormone secretion (GO:0030072)2.33240188
145kidney mesenchyme development (GO:0072074)2.32970856
146positive regulation of insulin secretion (GO:0032024)2.31249394
147signal transduction involved in regulation of gene expression (GO:0023019)2.30760740
148Leydig cell differentiation (GO:0033327)2.30144963
149inositol phosphate dephosphorylation (GO:0046855)2.30069191
150phosphorylated carbohydrate dephosphorylation (GO:0046838)2.30069191
151positive regulation of actin filament depolymerization (GO:0030836)2.29660198
152protein targeting to Golgi (GO:0000042)2.29551761
153cellular response to vitamin (GO:0071295)2.29456002
154peptide secretion (GO:0002790)2.28902061
155positive regulation of meiotic cell cycle (GO:0051446)2.27040858
156anterior/posterior axis specification, embryo (GO:0008595)2.26235712
157chondrocyte proliferation (GO:0035988)2.25841957
158dorsal/ventral axis specification (GO:0009950)2.25328540
159atrial cardiac muscle cell action potential (GO:0086014)2.23504828
160respiratory chain complex IV assembly (GO:0008535)2.23472222
161righting reflex (GO:0060013)2.23314988
162regulation of calcium ion-dependent exocytosis (GO:0017158)2.23112332
163lymphangiogenesis (GO:0001946)2.21863084
164axonal fasciculation (GO:0007413)2.21585764
165response to pheromone (GO:0019236)2.20815988
166alanine transport (GO:0032328)2.19422045
167reflex (GO:0060004)2.19304209
168glandular epithelial cell differentiation (GO:0002067)2.18424646
169positive regulation of peptide hormone secretion (GO:0090277)2.18312011
170pancreas development (GO:0031016)2.17547880
171protein localization to Golgi apparatus (GO:0034067)2.16750203
172negative regulation of execution phase of apoptosis (GO:1900118)2.16553639
173regulation of mesoderm development (GO:2000380)2.16518399
174COPII vesicle coating (GO:0048208)2.15794645
175protein heterotrimerization (GO:0070208)2.15511840
176negative regulation of glycogen metabolic process (GO:0070874)2.15265542
177cell migration involved in sprouting angiogenesis (GO:0002042)2.13949553
178magnesium ion transport (GO:0015693)2.13112289
179polyol catabolic process (GO:0046174)2.13059333
180intra-Golgi vesicle-mediated transport (GO:0006891)2.12889228
181response to redox state (GO:0051775)2.12099977
182paraxial mesoderm development (GO:0048339)2.11412281
183regulation of cell fate specification (GO:0042659)2.10600568
184positive regulation of peptide secretion (GO:0002793)2.08452839
185negative regulation of osteoblast proliferation (GO:0033689)2.07705040
186regulation of axon extension involved in axon guidance (GO:0048841)2.07026033
187regulation of insulin secretion (GO:0050796)2.06752265
188retrograde transport, vesicle recycling within Golgi (GO:0000301)2.05066542
189regulation of Rac protein signal transduction (GO:0035020)2.04946110

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.58379047
2GBX2_23144817_ChIP-Seq_PC3_Human4.55349967
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98641686
4TAF15_26573619_Chip-Seq_HEK293_Human2.90159476
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.75195467
6REST_21632747_ChIP-Seq_MESCs_Mouse2.66418278
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.58595359
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.51695902
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.49494599
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.47990388
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.46289746
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.43768028
13REST_18959480_ChIP-ChIP_MESCs_Mouse2.35005484
14CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.34960259
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.33952551
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.33028723
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30425799
18* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.26135193
19* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.20624736
20EZH2_18974828_ChIP-Seq_MESCs_Mouse2.20029995
21RNF2_18974828_ChIP-Seq_MESCs_Mouse2.20029995
22CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.17684147
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.15709594
24CTBP1_25329375_ChIP-Seq_LNCAP_Human2.14050626
25BMI1_23680149_ChIP-Seq_NPCS_Mouse2.12502085
26ZFP57_27257070_Chip-Seq_ESCs_Mouse2.10333787
27* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.07903199
28EED_16625203_ChIP-ChIP_MESCs_Mouse2.01143285
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.98930915
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.91575255
31SMAD4_21799915_ChIP-Seq_A2780_Human1.87036612
32P300_19829295_ChIP-Seq_ESCs_Human1.82769861
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81197609
34ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.79811293
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78304051
36AR_21572438_ChIP-Seq_LNCaP_Human1.77190727
37RARB_27405468_Chip-Seq_BRAIN_Mouse1.76684416
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.72622666
39SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72256768
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70201184
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69502318
42RNF2_27304074_Chip-Seq_ESCs_Mouse1.68650916
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.62966732
44NR3C1_23031785_ChIP-Seq_PC12_Mouse1.62473431
45TOP2B_26459242_ChIP-Seq_MCF-7_Human1.61444434
46EWS_26573619_Chip-Seq_HEK293_Human1.60325928
47RNF2_27304074_Chip-Seq_NSC_Mouse1.57042202
48DROSHA_22980978_ChIP-Seq_HELA_Human1.56965569
49FUS_26573619_Chip-Seq_HEK293_Human1.55945713
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.50984451
51MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.45833828
52AR_25329375_ChIP-Seq_VCAP_Human1.45809561
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44189001
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41011120
55HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.40000769
56BRD4_25478319_ChIP-Seq_HGPS_Human1.37821802
57IKZF1_21737484_ChIP-ChIP_HCT116_Human1.37620504
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37387715
59SOX2_21211035_ChIP-Seq_LN229_Gbm1.36895746
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36873744
61VDR_22108803_ChIP-Seq_LS180_Human1.36131256
62BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.35163537
63PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34532447
64ZNF274_21170338_ChIP-Seq_K562_Hela1.32663327
65* WT1_19549856_ChIP-ChIP_CCG9911_Human1.32328266
66IGF1R_20145208_ChIP-Seq_DFB_Human1.31475165
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.31041720
68TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.29938593
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29792259
70SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29104812
71RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.28834861
72SMAD_19615063_ChIP-ChIP_OVARY_Human1.28632421
73EP300_21415370_ChIP-Seq_HL-1_Mouse1.28201986
74EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.27074718
75JUN_21703547_ChIP-Seq_K562_Human1.26373605
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.26335195
77ERG_21242973_ChIP-ChIP_JURKAT_Human1.26013628
78FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.25410450
79STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24035442
80TP53_18474530_ChIP-ChIP_U2OS_Human1.23766230
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.20677697
82ER_23166858_ChIP-Seq_MCF-7_Human1.19597640
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19492064
84* STAT3_23295773_ChIP-Seq_U87_Human1.19231448
85* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.18942083
86PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16969396
87RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15588176
88RUNX2_22187159_ChIP-Seq_PCA_Human1.15346041
89* CJUN_26792858_Chip-Seq_BT549_Human1.14786132
90NFE2_27457419_Chip-Seq_LIVER_Mouse1.14336817
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13697483
92* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13331352
93P53_22387025_ChIP-Seq_ESCs_Mouse1.12127948
94PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11814955
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11549744
96FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.11397650
97SMAD3_21741376_ChIP-Seq_HESCs_Human1.09415584
98TCF4_23295773_ChIP-Seq_U87_Human1.08008555
99RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07778470
100SMAD4_21741376_ChIP-Seq_EPCs_Human1.07127470
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06885910
102CDX2_22108803_ChIP-Seq_LS180_Human1.06449781
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.06298007
104POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06185494
105CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.06153533
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06140221
107CMYC_18555785_Chip-Seq_ESCs_Mouse1.05268560
108E2F1_18555785_Chip-Seq_ESCs_Mouse1.04664362
109* ARNT_22903824_ChIP-Seq_MCF-7_Human1.04560849
110NRF2_20460467_ChIP-Seq_MEFs_Mouse1.03816826
111NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.03816826
112CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.02807194
113TBX3_20139965_ChIP-Seq_MESCs_Mouse1.02736841
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.02383657
115STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01717579
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01564090
117TBX3_20139965_ChIP-Seq_ESCs_Mouse1.01219824
118SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00792359
119CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99223002
120TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98437137
121PRDM14_20953172_ChIP-Seq_ESCs_Human0.98137271
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97878279
123REST_19997604_ChIP-ChIP_NEURONS_Mouse0.97482737
124MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97230234
125RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96830257
126* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94534864
127HTT_18923047_ChIP-ChIP_STHdh_Human0.92763450
128BCAT_22108803_ChIP-Seq_LS180_Human0.90475705
129NANOG_18555785_Chip-Seq_ESCs_Mouse0.89086819
130CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.87446108
131KDM2B_26808549_Chip-Seq_REH_Human0.87433029
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.85774606
133RING1B_27294783_Chip-Seq_ESCs_Mouse0.85063177
134SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84360317
135TCF4_22108803_ChIP-Seq_LS180_Human0.84228598
136AR_19668381_ChIP-Seq_PC3_Human0.84089425
137NR3C1_21868756_ChIP-Seq_MCF10A_Human0.82801070
138CDX2_19796622_ChIP-Seq_MESCs_Mouse0.82335811
139FLI1_21867929_ChIP-Seq_TH2_Mouse0.82039628
140* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81576730
141* CBP_20019798_ChIP-Seq_JUKART_Human0.81576730

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy4.70760519
2MP0004859_abnormal_synaptic_plasticity3.85207413
3MP0003283_abnormal_digestive_organ3.31535144
4MP0003635_abnormal_synaptic_transmissio3.31291797
5MP0009046_muscle_twitch3.28034940
6MP0009745_abnormal_behavioral_response3.15164690
7MP0002064_seizures3.05253111
8MP0004270_analgesia3.05020098
9MP0003122_maternal_imprinting3.00795004
10MP0001529_abnormal_vocalization2.86491455
11MP0003787_abnormal_imprinting2.80818592
12MP0002572_abnormal_emotion/affect_behav2.76474629
13MP0010386_abnormal_urinary_bladder2.73507817
14MP0002063_abnormal_learning/memory/cond2.67690808
15MP0002734_abnormal_mechanical_nocicepti2.67314129
16MP0002272_abnormal_nervous_system2.60625948
17MP0003880_abnormal_central_pattern2.59065031
18MP0001501_abnormal_sleep_pattern2.49611637
19MP0001968_abnormal_touch/_nociception2.48390137
20MP0006276_abnormal_autonomic_nervous2.44994890
21MP0005646_abnormal_pituitary_gland2.44414801
22MP0002638_abnormal_pupillary_reflex2.40010057
23MP0001440_abnormal_grooming_behavior2.27529820
24MP0002736_abnormal_nociception_after2.25110026
25MP0005645_abnormal_hypothalamus_physiol2.23417502
26MP0001970_abnormal_pain_threshold2.14959367
27MP0002102_abnormal_ear_morphology2.11819262
28MP0001905_abnormal_dopamine_level2.10161598
29MP0002254_reproductive_system_inflammat2.08312567
30MP0009780_abnormal_chondrocyte_physiolo2.06754235
31MP0003195_calcinosis2.02835698
32MP0008438_abnormal_cutaneous_collagen2.02449683
33MP0002733_abnormal_thermal_nociception2.02200694
34MP0001984_abnormal_olfaction1.92484682
35MP0002735_abnormal_chemical_nociception1.92459507
36MP0002876_abnormal_thyroid_physiology1.87774951
37MP0004133_heterotaxia1.87194140
38MP0002837_dystrophic_cardiac_calcinosis1.85249817
39MP0001486_abnormal_startle_reflex1.82806357
40MP0001299_abnormal_eye_distance/1.80242217
41MP0000013_abnormal_adipose_tissue1.79039865
42MP0002067_abnormal_sensory_capabilities1.74769905
43MP0000569_abnormal_digit_pigmentation1.74352143
44MP0001944_abnormal_pancreas_morphology1.74328497
45MP0005386_behavior/neurological_phenoty1.74166515
46MP0004924_abnormal_behavior1.74166515
47MP0004142_abnormal_muscle_tone1.70233547
48MP0002557_abnormal_social/conspecific_i1.65798912
49MP0009384_cardiac_valve_regurgitation1.62928549
50MP0002184_abnormal_innervation1.59071452
51MP0004858_abnormal_nervous_system1.58679063
52MP0002938_white_spotting1.55542808
53MP0003890_abnormal_embryonic-extraembry1.55428884
54MP0006054_spinal_hemorrhage1.51817412
55MP0003879_abnormal_hair_cell1.51112773
56MP0005084_abnormal_gallbladder_morpholo1.50904863
57MP0008877_abnormal_DNA_methylation1.48390874
58MP0003646_muscle_fatigue1.46914053
59MP0001188_hyperpigmentation1.44047913
60MP0002295_abnormal_pulmonary_circulatio1.42005158
61MP0002909_abnormal_adrenal_gland1.40504927
62MP0008569_lethality_at_weaning1.35278000
63MP0002693_abnormal_pancreas_physiology1.34180997
64MP0004811_abnormal_neuron_physiology1.32926238
65MP0008872_abnormal_physiological_respon1.30056525
66MP0003121_genomic_imprinting1.29759616
67MP0003941_abnormal_skin_development1.29028104
68MP0004272_abnormal_basement_membrane1.28238964
69MP0004043_abnormal_pH_regulation1.25251521
70MP0005423_abnormal_somatic_nervous1.25163823
71MP0005220_abnormal_exocrine_pancreas1.24981530
72MP0001986_abnormal_taste_sensitivity1.23728964
73MP0000955_abnormal_spinal_cord1.21993590
74MP0000778_abnormal_nervous_system1.21817009
75MP0010352_gastrointestinal_tract_polyps1.21673894
76MP0002066_abnormal_motor_capabilities/c1.20404944
77MP0003937_abnormal_limbs/digits/tail_de1.20130019
78MP0005623_abnormal_meninges_morphology1.18521091
79MP0005257_abnormal_intraocular_pressure1.18448046
80MP0005499_abnormal_olfactory_system1.16537723
81MP0005394_taste/olfaction_phenotype1.16537723
82MP0002928_abnormal_bile_duct1.16375360
83MP0005503_abnormal_tendon_morphology1.16178568
84MP0000751_myopathy1.14182772
85MP0002882_abnormal_neuron_morphology1.13054044
86MP0000427_abnormal_hair_cycle1.12785533
87MP0002751_abnormal_autonomic_nervous1.08503946
88MP0003119_abnormal_digestive_system1.08083361
89MP0000003_abnormal_adipose_tissue1.06944178
90MP0003279_aneurysm1.04671959
91MP0005187_abnormal_penis_morphology1.04657586
92MP0001756_abnormal_urination1.02942143
93MP0002163_abnormal_gland_morphology1.02873257
94MP0001542_abnormal_bone_strength1.01094403
95MP0006292_abnormal_olfactory_placode0.98960428
96MP0000462_abnormal_digestive_system0.98820846
97MP0000631_abnormal_neuroendocrine_gland0.98638121
98MP0003950_abnormal_plasma_membrane0.97373231
99MP0003942_abnormal_urinary_system0.95896330
100MP0002069_abnormal_eating/drinking_beha0.95696617
101MP0000516_abnormal_urinary_system0.93479909
102MP0005367_renal/urinary_system_phenotyp0.93479909
103MP0000538_abnormal_urinary_bladder0.92876698
104MP0003633_abnormal_nervous_system0.92032853
105MP0003183_abnormal_peptide_metabolism0.91694945
106MP0005253_abnormal_eye_physiology0.90993048
107MP0002177_abnormal_outer_ear0.90712558
108MP0004134_abnormal_chest_morphology0.89554930
109MP0001502_abnormal_circadian_rhythm0.86768635
110MP0002152_abnormal_brain_morphology0.84487427
111MP0005379_endocrine/exocrine_gland_phen0.84262066
112MP0001664_abnormal_digestion0.83331964
113MP0002078_abnormal_glucose_homeostasis0.82677919
114MP0000639_abnormal_adrenal_gland0.82607876
115MP0003631_nervous_system_phenotype0.80540383
116MP0003329_amyloid_beta_deposits0.80510692
117MP0005535_abnormal_body_temperature0.80233137
118MP0008789_abnormal_olfactory_epithelium0.79467539
119MP0006036_abnormal_mitochondrial_physio0.79369701
120MP0003755_abnormal_palate_morphology0.78029871
121MP0004233_abnormal_muscle_weight0.77786149
122MP0001963_abnormal_hearing_physiology0.77260976
123MP0006035_abnormal_mitochondrial_morpho0.77051827
124MP0004085_abnormal_heartbeat0.76828591
125MP0005551_abnormal_eye_electrophysiolog0.76300591
126MP0005332_abnormal_amino_acid0.76180401
127MP0002229_neurodegeneration0.75863747
128MP0003123_paternal_imprinting0.75682156
129MP0002160_abnormal_reproductive_system0.75590810
130MP0000372_irregular_coat_pigmentation0.74725339
131MP0009697_abnormal_copulation0.74426544
132MP0010368_abnormal_lymphatic_system0.72896735
133MP0004036_abnormal_muscle_relaxation0.71968186
134MP0001958_emphysema0.71458796
135MP0006072_abnormal_retinal_apoptosis0.69532279
136MP0002332_abnormal_exercise_endurance0.68653653
137MP0008874_decreased_physiological_sensi0.67765045
138MP0002752_abnormal_somatic_nervous0.66182876
139MP0002653_abnormal_ependyma_morphology0.65412917
140MP0004484_altered_response_of0.61637833
141MP0003953_abnormal_hormone_level0.60518611
142MP0004215_abnormal_myocardial_fiber0.59697781
143MP0002090_abnormal_vision0.57217760
144MP0001177_atelectasis0.55095776
145MP0000230_abnormal_systemic_arterial0.53908818
146MP0005171_absent_coat_pigmentation0.53830485
147MP0002127_abnormal_cardiovascular_syste0.53123008
148MP0003634_abnormal_glial_cell0.51940176

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.24728509
2Hypothermia (HP:0002045)5.88800114
3Myokymia (HP:0002411)5.67494976
4Atonic seizures (HP:0010819)5.06853375
5Abnormal hair whorl (HP:0010721)4.40382379
6Acute necrotizing encephalopathy (HP:0006965)4.37815160
7Febrile seizures (HP:0002373)4.31208650
8Abnormal mitochondria in muscle tissue (HP:0008316)4.30497192
9Focal seizures (HP:0007359)4.08174448
10Pheochromocytoma (HP:0002666)4.03875742
11Oligomenorrhea (HP:0000876)3.91354999
12Neuroendocrine neoplasm (HP:0100634)3.89518871
13Progressive macrocephaly (HP:0004481)3.76862720
14Polyphagia (HP:0002591)3.75814453
15Intestinal atresia (HP:0011100)3.75041676
16Failure to thrive in infancy (HP:0001531)3.71689277
17Mitochondrial inheritance (HP:0001427)3.69212265
18Epileptic encephalopathy (HP:0200134)3.69203649
19Absence seizures (HP:0002121)3.67054881
20Gait imbalance (HP:0002141)3.55296692
21Hypoglycemic seizures (HP:0002173)3.54734725
22Visual hallucinations (HP:0002367)3.52140225
23Progressive cerebellar ataxia (HP:0002073)3.49855119
24Poor suck (HP:0002033)3.42090530
25Acute encephalopathy (HP:0006846)3.41371283
26Generalized tonic-clonic seizures (HP:0002069)3.39203403
27Limb dystonia (HP:0002451)3.38563096
28Hepatocellular necrosis (HP:0001404)3.37631987
29Hyperinsulinemic hypoglycemia (HP:0000825)3.34775960
30Hypoglycemic coma (HP:0001325)3.32131749
31Congenital primary aphakia (HP:0007707)3.26173002
32Abnormality of the labia minora (HP:0012880)3.24601256
33Medial flaring of the eyebrow (HP:0010747)3.19974540
34Congenital malformation of the right heart (HP:0011723)3.18027342
35Double outlet right ventricle (HP:0001719)3.18027342
36Increased CSF lactate (HP:0002490)3.15847265
37Dialeptic seizures (HP:0011146)3.09770641
38Nephrogenic diabetes insipidus (HP:0009806)3.05112714
39Hyperglycemia (HP:0003074)3.03595710
40Abnormal eating behavior (HP:0100738)2.92058841
41Ketoacidosis (HP:0001993)2.89869043
42Hyperventilation (HP:0002883)2.87642922
43Impaired vibration sensation in the lower limbs (HP:0002166)2.81553565
44Amblyopia (HP:0000646)2.76579327
45Epileptiform EEG discharges (HP:0011182)2.71643418
46Abnormal pancreas size (HP:0012094)2.69224538
47Abnormality of pain sensation (HP:0010832)2.66866611
48Impaired pain sensation (HP:0007328)2.66866611
49Orthostatic hypotension (HP:0001278)2.66290726
50Abnormality of abdominal situs (HP:0011620)2.64157938
51Abdominal situs inversus (HP:0003363)2.64157938
52EEG with generalized epileptiform discharges (HP:0011198)2.62099774
53Premature rupture of membranes (HP:0001788)2.61848321
54Pancreatic fibrosis (HP:0100732)2.61632352
55Hypoventilation (HP:0002791)2.61171718
56Resting tremor (HP:0002322)2.58354608
57Hypsarrhythmia (HP:0002521)2.56123212
58Hepatic necrosis (HP:0002605)2.54661097
59Specific learning disability (HP:0001328)2.53548737
60Genital tract atresia (HP:0001827)2.53220817
61Abnormal autonomic nervous system physiology (HP:0012332)2.53052044
62Delayed gross motor development (HP:0002194)2.52920068
63Anxiety (HP:0000739)2.51920609
64Cardiovascular calcification (HP:0011915)2.49255410
65Hyperthyroidism (HP:0000836)2.49192713
66Increased serum pyruvate (HP:0003542)2.47851169
67Abnormality of glycolysis (HP:0004366)2.47851169
68Large for gestational age (HP:0001520)2.44238332
69Nephronophthisis (HP:0000090)2.42794582
70Vaginal atresia (HP:0000148)2.42183860
71Aqueductal stenosis (HP:0002410)2.42053556
72Enlarged penis (HP:0000040)2.41316393
73Hemiparesis (HP:0001269)2.41089607
74Poor coordination (HP:0002370)2.37337510
75Narrow nasal bridge (HP:0000446)2.34410786
76Abnormality of binocular vision (HP:0011514)2.30476486
77Diplopia (HP:0000651)2.30476486
78Optic disc pallor (HP:0000543)2.30430929
79Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.28060880
80Molar tooth sign on MRI (HP:0002419)2.26567881
81Abnormality of midbrain morphology (HP:0002418)2.26567881
82Abnormal albumin level (HP:0012116)2.25791665
83Hypoalbuminemia (HP:0003073)2.25791665
84Abnormality of dentin (HP:0010299)2.24982352
85Vascular calcification (HP:0004934)2.20664932
86Follicular hyperkeratosis (HP:0007502)2.20106624
87Agitation (HP:0000713)2.19479382
88Esotropia (HP:0000565)2.19199518
89Leukodystrophy (HP:0002415)2.18965960
90Respiratory failure (HP:0002878)2.16553157
91Disproportionate short-trunk short stature (HP:0003521)2.13315605
92Cerebral edema (HP:0002181)2.12238765
93Abnormality of endocrine pancreas physiology (HP:0012093)2.10479285
94Abnormality of the pancreatic islet cells (HP:0006476)2.10479285
95Aplasia/Hypoplasia of the lens (HP:0008063)2.09497546
96Progressive inability to walk (HP:0002505)2.09342065
97Pancreatic cysts (HP:0001737)2.07022275
98Depression (HP:0000716)2.06244138
99Autoamputation (HP:0001218)2.05101521
100Sleep apnea (HP:0010535)2.03511313
101Emotional lability (HP:0000712)2.02619760
102Broad metatarsal (HP:0001783)2.02495765
103Late onset (HP:0003584)1.99653015
104Neoplasm of the peripheral nervous system (HP:0100007)1.99568141
105Methylmalonic acidemia (HP:0002912)1.98947361
106Prominent metopic ridge (HP:0005487)1.98925660
107Focal dystonia (HP:0004373)1.98178302
108Hyperphosphatemia (HP:0002905)1.97927856
109Abnormality of vitamin B metabolism (HP:0004340)1.97551600
110True hermaphroditism (HP:0010459)1.96618997
111Neonatal hypoglycemia (HP:0001998)1.95796291
112Generalized hypotonia (HP:0001290)1.93521165
113Dysdiadochokinesis (HP:0002075)1.93277241
114Lactic acidosis (HP:0003128)1.92794826
115Menstrual irregularities (HP:0000858)1.92406683
116Symptomatic seizures (HP:0011145)1.91708294
117Cortical visual impairment (HP:0100704)1.90968761
118Insulin-resistant diabetes mellitus (HP:0000831)1.90791400
119Abnormality of the renal medulla (HP:0100957)1.90389253
120Ankle clonus (HP:0011448)1.90359311
121Labial hypoplasia (HP:0000066)1.89564143
122Psychosis (HP:0000709)1.88803412
123Abnormality of the renal cortex (HP:0011035)1.87793729
124Broad-based gait (HP:0002136)1.84590321
125Gaze-evoked nystagmus (HP:0000640)1.84375792
126Abnormality of the metopic suture (HP:0005556)1.84028297
127Soft skin (HP:0000977)1.83974043
128CNS demyelination (HP:0007305)1.83432596
129Sensory axonal neuropathy (HP:0003390)1.82998142
130Drooling (HP:0002307)1.82265415
131Torticollis (HP:0000473)1.81061872
132Dysmetria (HP:0001310)1.80467989
133Truncal ataxia (HP:0002078)1.79515390
134Craniofacial dystonia (HP:0012179)1.79311077
135Exercise intolerance (HP:0003546)1.77632400
136Tubular atrophy (HP:0000092)1.77048468
137Hip dysplasia (HP:0001385)1.76826238
138Long foot (HP:0001833)1.76458597
139Exotropia (HP:0000577)1.75850373
140Impaired vibratory sensation (HP:0002495)1.75772798
141X-linked dominant inheritance (HP:0001423)1.75125305
142Ketosis (HP:0001946)1.74351841
143Broad foot (HP:0001769)1.74320368
144Nasal speech (HP:0001611)1.74227984
145Type II lissencephaly (HP:0007260)1.74051616
146Short hallux (HP:0010109)1.72843747
147Aplasia/Hypoplasia of the hallux (HP:0008362)1.71410683
148Hypoplastic female external genitalia (HP:0012815)1.71123116
149Unilateral renal agenesis (HP:0000122)1.71006485
150Action tremor (HP:0002345)1.69397633
151Muscular hypotonia of the trunk (HP:0008936)1.69197399
152Gastrointestinal atresia (HP:0002589)1.66394985
153Ankle contracture (HP:0006466)1.66114222
154Increased corneal curvature (HP:0100692)1.64306315
155Keratoconus (HP:0000563)1.64306315
156Optic nerve hypoplasia (HP:0000609)1.63719062
157Abnormality of aromatic amino acid family metabolism (HP:0004338)1.63033933
158Renal cortical cysts (HP:0000803)1.62732034
159Bradycardia (HP:0001662)1.62715074
160Bowel diverticulosis (HP:0005222)1.59600610
161Overgrowth (HP:0001548)1.59185359
162Hypogonadotrophic hypogonadism (HP:0000044)1.57290496
163Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.56666542
164Genetic anticipation (HP:0003743)1.55807175
165Buphthalmos (HP:0000557)1.54930038
166Neoplasm of the adrenal cortex (HP:0100641)1.52895660
167Nuclear cataract (HP:0100018)1.52881616
168Abnormal biliary tract morphology (HP:0012440)1.52228895
169Hydroxyprolinuria (HP:0003080)1.52213389
170Abnormality of proline metabolism (HP:0010907)1.52213389
171Bifid tongue (HP:0010297)1.51308728
172Downturned corners of mouth (HP:0002714)1.50951044
173Excessive salivation (HP:0003781)1.50446228
174Abnormality of vitamin metabolism (HP:0100508)1.49926218
175Aplasia/Hypoplasia of the tongue (HP:0010295)1.49827706
176Shawl scrotum (HP:0000049)1.48434642

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.22671462
2MAP3K124.61287429
3MAP3K44.02153371
4MAP2K73.93364198
5CASK3.75713463
6TSSK63.30111182
7NTRK33.18666315
8GRK72.73009838
9MAP4K22.38746890
10GRK12.38155898
11MAP2K42.36930720
12AKT32.32462339
13MARK12.27107911
14MINK12.06957233
15GRK52.05438817
16NTRK12.03827411
17NTRK22.00533788
18DAPK11.91123480
19FGFR21.90933363
20MAP3K91.90928111
21PLK21.87888656
22CDK191.87318543
23ARAF1.85736685
24NME11.83066828
25STK38L1.63769686
26PDK31.48134469
27PDK41.48134469
28DAPK21.40435927
29PRKCG1.38916028
30SIK31.34811386
31PINK11.33486692
32MYLK1.30767463
33OXSR11.29997495
34STK31.29563939
35MAPK131.27657045
36PTK21.25603094
37ACVR1B1.23588850
38BRAF1.16206103
39PRPF4B1.13471285
40NLK1.13405415
41UHMK11.12945865
42PRKD31.12164425
43TRIM281.11855889
44PRKCE1.11261398
45MKNK21.10717844
46SGK4941.07721931
47SGK2231.07721931
48CAMK2B1.06294157
49LATS11.06143214
50CDK51.05195225
51SGK21.02535873
52ERBB41.01348837
53CAMK1G1.00471805
54PRKD21.00122021
55ADRBK10.99723278
56STK380.98297271
57TRPM70.97625068
58CAMK2A0.97107935
59WNK30.95446254
60FLT30.92889204
61INSRR0.92677066
62CSNK1G20.92571529
63MAP3K20.91823207
64PTK2B0.91816776
65NUAK10.90569261
66LIMK10.88781213
67STK390.88060743
68CSNK1A1L0.83736250
69MAP2K10.81462404
70PDK20.80853789
71PLK30.80574708
72EPHA40.80374961
73PNCK0.79113332
74CSNK1G30.79006608
75BMPR1B0.78431455
76CAMK2G0.75721233
77PHKG20.74395739
78PHKG10.74395739
79NEK10.73278795
80CDK180.73244736
81BCR0.73000739
82RPS6KA20.72884367
83MAP2K60.70607209
84ZAK0.69821636
85CAMKK20.68819091
86CDK140.68339025
87CAMK2D0.66626134
88CCNB10.66108377
89ADRBK20.65582558
90PAK20.65150533
91CDK150.64654002
92PASK0.64244739
93PAK30.61542273
94BMPR20.61166624
95KSR10.61130859
96CDK80.58727732
97PAK60.57923139
98PRKAA10.57366330
99ROCK10.56947656
100MST40.56792565
101TNIK0.56385188
102CAMKK10.53197903
103STK160.53125604
104CDK11A0.53079365
105SGK30.52862669
106KSR20.52506085
107FES0.50071416
108WNK10.49418230
109PDGFRA0.48334684
110MAP3K60.46785303
111WNK40.46569960
112FER0.46316073
113EIF2AK30.45889417
114PRKCI0.45632227
115FGFR10.45560144
116DDR20.45280440
117DAPK30.45257232
118BRSK20.44527118
119ROCK20.44229577
120PRKACA0.43560088
121DYRK20.42949678
122DYRK1A0.42824258
123PRKCH0.42503617
124MAPKAPK50.42491640
125PRKG10.42450079
126TNK20.41881024
127CSNK1E0.41614810
128SGK10.40366391
129MATK0.39561050
130GSK3A0.39013578
131CSNK1G10.38816818
132CSNK1A10.38688545
133PRKG20.38060838
134CSNK1D0.37792069
135TIE10.36602239
136CAMK10.33453539
137PRKCZ0.32888448
138FGFR30.32538366
139TESK10.31958927
140SIK20.30482851
141PRKCB0.30040617
142ERBB30.29849719
143LATS20.29666405
144RPS6KL10.29444365
145RPS6KC10.29444365
146RPS6KB10.29054266
147MARK20.28012170

Predicted pathways (KEGG)

RankGene SetZ-score
1Collecting duct acid secretion_Homo sapiens_hsa049664.18523564
2Synaptic vesicle cycle_Homo sapiens_hsa047214.17246555
3Oxidative phosphorylation_Homo sapiens_hsa001903.46392992
4Nicotine addiction_Homo sapiens_hsa050333.05119303
5Vibrio cholerae infection_Homo sapiens_hsa051103.01122683
6Parkinsons disease_Homo sapiens_hsa050122.59720367
7Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.59421191
8Olfactory transduction_Homo sapiens_hsa047402.35746642
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.35057633
10GABAergic synapse_Homo sapiens_hsa047272.33394200
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.24868882
12Selenocompound metabolism_Homo sapiens_hsa004502.19058245
13Amphetamine addiction_Homo sapiens_hsa050312.13331494
14Circadian entrainment_Homo sapiens_hsa047132.01946252
15Alzheimers disease_Homo sapiens_hsa050102.01105749
16Dopaminergic synapse_Homo sapiens_hsa047281.97973894
17Morphine addiction_Homo sapiens_hsa050321.94649511
18Cocaine addiction_Homo sapiens_hsa050301.82172762
19Insulin secretion_Homo sapiens_hsa049111.80363041
20Taste transduction_Homo sapiens_hsa047421.78063858
21Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.77268214
22Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.75555176
23Serotonergic synapse_Homo sapiens_hsa047261.73906947
24Huntingtons disease_Homo sapiens_hsa050161.69535981
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.67870784
26Glutamatergic synapse_Homo sapiens_hsa047241.65275712
27Long-term potentiation_Homo sapiens_hsa047201.63037636
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.62447375
29Cholinergic synapse_Homo sapiens_hsa047251.55799236
30Long-term depression_Homo sapiens_hsa047301.54438421
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50971081
32Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.46296152
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.38781227
34Rheumatoid arthritis_Homo sapiens_hsa053231.37449299
35Pyruvate metabolism_Homo sapiens_hsa006201.35169608
36Salivary secretion_Homo sapiens_hsa049701.31394633
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.29871340
38Folate biosynthesis_Homo sapiens_hsa007901.28626720
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.21775194
40Phenylalanine metabolism_Homo sapiens_hsa003601.21383859
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.19955175
42Renin secretion_Homo sapiens_hsa049241.19362977
43Type I diabetes mellitus_Homo sapiens_hsa049401.17667600
44Hedgehog signaling pathway_Homo sapiens_hsa043401.17111930
45Circadian rhythm_Homo sapiens_hsa047101.16349361
46Phagosome_Homo sapiens_hsa041451.16289907
47Gastric acid secretion_Homo sapiens_hsa049711.09382267
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08730519
49Hippo signaling pathway_Homo sapiens_hsa043901.07421661
50Aldosterone synthesis and secretion_Homo sapiens_hsa049251.06459706
51Tyrosine metabolism_Homo sapiens_hsa003501.06227341
52Cardiac muscle contraction_Homo sapiens_hsa042601.04743869
53Proteasome_Homo sapiens_hsa030501.02967058
54Calcium signaling pathway_Homo sapiens_hsa040201.02216865
55Gap junction_Homo sapiens_hsa045400.99643575
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.98465625
57Sphingolipid metabolism_Homo sapiens_hsa006000.95336440
58TGF-beta signaling pathway_Homo sapiens_hsa043500.93661825
59Butanoate metabolism_Homo sapiens_hsa006500.93086254
60Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91680346
612-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90525998
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88338738
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87734249
64Propanoate metabolism_Homo sapiens_hsa006400.87401871
65Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86619489
66Basal transcription factors_Homo sapiens_hsa030220.85849395
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85737972
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.85575745
69Basal cell carcinoma_Homo sapiens_hsa052170.83933304
70Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.83417560
71Tryptophan metabolism_Homo sapiens_hsa003800.83138853
72Oxytocin signaling pathway_Homo sapiens_hsa049210.81244753
73GnRH signaling pathway_Homo sapiens_hsa049120.78871918
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77228594
75ECM-receptor interaction_Homo sapiens_hsa045120.74886338
76Wnt signaling pathway_Homo sapiens_hsa043100.73858524
77Ether lipid metabolism_Homo sapiens_hsa005650.72613225
78Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70499722
79* Tight junction_Homo sapiens_hsa045300.70401318
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.70025017
81cAMP signaling pathway_Homo sapiens_hsa040240.69166693
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68140830
83Protein digestion and absorption_Homo sapiens_hsa049740.67741182
84Peroxisome_Homo sapiens_hsa041460.67221035
85N-Glycan biosynthesis_Homo sapiens_hsa005100.66591809
86Dorso-ventral axis formation_Homo sapiens_hsa043200.65190659
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.64233375
88Estrogen signaling pathway_Homo sapiens_hsa049150.63833385
89Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63112705
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.63036584
91Primary bile acid biosynthesis_Homo sapiens_hsa001200.61808732
92Type II diabetes mellitus_Homo sapiens_hsa049300.61726530
93Fatty acid elongation_Homo sapiens_hsa000620.60387499
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60053231
95Vitamin B6 metabolism_Homo sapiens_hsa007500.59922336
96Alcoholism_Homo sapiens_hsa050340.59908394
97Sulfur metabolism_Homo sapiens_hsa009200.57624433
98Phototransduction_Homo sapiens_hsa047440.57514516
99Mineral absorption_Homo sapiens_hsa049780.55988148
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54145332
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53129341
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52682094
103beta-Alanine metabolism_Homo sapiens_hsa004100.51718930
104Protein export_Homo sapiens_hsa030600.51555778
105Thyroid hormone synthesis_Homo sapiens_hsa049180.51353743
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48178506
107Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48161722
108Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.47946955
109Focal adhesion_Homo sapiens_hsa045100.47700677
110Regulation of autophagy_Homo sapiens_hsa041400.47634069
111Glucagon signaling pathway_Homo sapiens_hsa049220.47340960
112Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46749274
113RNA polymerase_Homo sapiens_hsa030200.46541005
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45330491
115Axon guidance_Homo sapiens_hsa043600.44059789
116Melanogenesis_Homo sapiens_hsa049160.43908994
117Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42949908
118Pancreatic secretion_Homo sapiens_hsa049720.42919583
119ErbB signaling pathway_Homo sapiens_hsa040120.41841994
120Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37760123
121Carbon metabolism_Homo sapiens_hsa012000.32782107
122Ovarian steroidogenesis_Homo sapiens_hsa049130.31997347
123Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31605455
124Oocyte meiosis_Homo sapiens_hsa041140.30908931
125Dilated cardiomyopathy_Homo sapiens_hsa054140.29071692
126MAPK signaling pathway_Homo sapiens_hsa040100.28018847
127Histidine metabolism_Homo sapiens_hsa003400.25208534
128Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24506751
129Cysteine and methionine metabolism_Homo sapiens_hsa002700.24188074
130Arginine biosynthesis_Homo sapiens_hsa002200.22839251
131Maturity onset diabetes of the young_Homo sapiens_hsa049500.22768000
132Prion diseases_Homo sapiens_hsa050200.22297454
133Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21582639
134Ras signaling pathway_Homo sapiens_hsa040140.21397456
135Glioma_Homo sapiens_hsa052140.20250042
136Metabolic pathways_Homo sapiens_hsa011000.20107296
137Insulin signaling pathway_Homo sapiens_hsa049100.17564474
138Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.16442919
139Melanoma_Homo sapiens_hsa052180.14715332
140Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.13859924

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