RAB40C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)4.67725173
2central nervous system myelination (GO:0022010)4.67725173
3synaptic vesicle maturation (GO:0016188)4.47928652
4layer formation in cerebral cortex (GO:0021819)4.45543077
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.36768261
6dendritic spine morphogenesis (GO:0060997)4.33191343
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.20964222
8regulation of short-term neuronal synaptic plasticity (GO:0048172)4.19886571
9cell migration in hindbrain (GO:0021535)4.10818735
10locomotory exploration behavior (GO:0035641)4.06527689
11establishment of mitochondrion localization (GO:0051654)4.02897441
12semaphorin-plexin signaling pathway (GO:0071526)3.98093072
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.95227446
14synaptic vesicle exocytosis (GO:0016079)3.90391563
15negative regulation of erythrocyte differentiation (GO:0045647)3.88918551
16negative regulation of cell size (GO:0045792)3.88474250
17protein localization to synapse (GO:0035418)3.84837939
18regulation of ARF protein signal transduction (GO:0032012)3.84711562
19neuron cell-cell adhesion (GO:0007158)3.73605199
20cytoskeletal anchoring at plasma membrane (GO:0007016)3.64702104
21dendrite morphogenesis (GO:0048813)3.61432954
22mannose metabolic process (GO:0006013)3.61361956
23positive regulation of synapse maturation (GO:0090129)3.58597167
24axon ensheathment (GO:0008366)3.56203351
25ensheathment of neurons (GO:0007272)3.56203351
26regulation of synaptic vesicle exocytosis (GO:2000300)3.53406286
27neuromuscular process controlling balance (GO:0050885)3.52253879
28myelination (GO:0042552)3.51253858
29GDP-mannose metabolic process (GO:0019673)3.49864541
30peptidyl-tyrosine autophosphorylation (GO:0038083)3.48391630
31establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.46850077
32mitochondrion transport along microtubule (GO:0047497)3.46850077
33glutamate secretion (GO:0014047)3.46544588
34regulation of dendritic spine morphogenesis (GO:0061001)3.42548946
35G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.40486507
36protein retention in ER lumen (GO:0006621)3.39941428
37vocalization behavior (GO:0071625)3.39364179
38axonal fasciculation (GO:0007413)3.36703445
39central nervous system projection neuron axonogenesis (GO:0021952)3.36138804
40positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.36096447
41neuromuscular process controlling posture (GO:0050884)3.31881351
42regulation of glutamate receptor signaling pathway (GO:1900449)3.30096365
43cell-cell junction maintenance (GO:0045217)3.29264705
44ionotropic glutamate receptor signaling pathway (GO:0035235)3.26092433
45neuron recognition (GO:0008038)3.26004296
46establishment of nucleus localization (GO:0040023)3.25050222
47cerebellar granule cell differentiation (GO:0021707)3.24044612
48regulation of neuronal synaptic plasticity (GO:0048168)3.22038496
49exploration behavior (GO:0035640)3.21773853
50regulation of ARF GTPase activity (GO:0032312)3.20202016
51neuronal action potential propagation (GO:0019227)3.18404536
52regulation of long-term neuronal synaptic plasticity (GO:0048169)3.14351220
53regulation of synaptic vesicle transport (GO:1902803)3.13230205
54synaptic transmission, glutamatergic (GO:0035249)3.12501821
55cerebellar Purkinje cell layer development (GO:0021680)3.12417479
56regulation of clathrin-mediated endocytosis (GO:2000369)3.09073528
57regulation of synapse structural plasticity (GO:0051823)3.08706994
58positive regulation of membrane potential (GO:0045838)3.08687879
59negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.05832735
60synaptic vesicle docking involved in exocytosis (GO:0016081)3.04847154
61negative regulation of microtubule polymerization (GO:0031115)3.03746407
62negative regulation of macroautophagy (GO:0016242)3.02467629
63proline biosynthetic process (GO:0006561)3.02120965
64transmission of nerve impulse (GO:0019226)3.00482541
65negative regulation of axonogenesis (GO:0050771)2.99718608
66dendritic spine organization (GO:0097061)2.98197767
67long-chain fatty acid biosynthetic process (GO:0042759)2.92577197
68adult walking behavior (GO:0007628)2.91715899
69regulation of synapse maturation (GO:0090128)2.91656228
70presynaptic membrane assembly (GO:0097105)2.91166948
71gamma-aminobutyric acid transport (GO:0015812)2.89927209
72regulation of female receptivity (GO:0045924)2.89219706
73sodium ion export (GO:0071436)2.88279361
74maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.87403686
75planar cell polarity pathway involved in neural tube closure (GO:0090179)2.86748199
76presynaptic membrane organization (GO:0097090)2.85780186
77neuromuscular process (GO:0050905)2.84311689
78intracellular estrogen receptor signaling pathway (GO:0030520)2.83461116
79regulation of dendritic spine development (GO:0060998)2.82312816
80L-amino acid import (GO:0043092)2.78510529
81organelle transport along microtubule (GO:0072384)2.76990182
82membrane tubulation (GO:0097320)2.75962232
83synaptic vesicle endocytosis (GO:0048488)2.75599834
84protein localization to endosome (GO:0036010)2.74973871
85apical protein localization (GO:0045176)2.73830816
86detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.73273882
87detection of temperature stimulus involved in sensory perception (GO:0050961)2.73273882
88regulation of excitatory postsynaptic membrane potential (GO:0060079)2.73068137
89neuronal ion channel clustering (GO:0045161)2.72370419
90neuron-neuron synaptic transmission (GO:0007270)2.72195305
91activation of protein kinase A activity (GO:0034199)2.72039695
92negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.71171602
93dopamine receptor signaling pathway (GO:0007212)2.70104268
94glutamate receptor signaling pathway (GO:0007215)2.69474212
95neurotransmitter secretion (GO:0007269)2.69460722
96oligodendrocyte differentiation (GO:0048709)2.68713871
97positive regulation of Cdc42 GTPase activity (GO:0043089)2.68591235
98negative regulation of axon extension (GO:0030517)2.65044184
99regulation of axon extension involved in axon guidance (GO:0048841)2.64895669
100regulation of collateral sprouting (GO:0048670)2.64580087
101adenosine receptor signaling pathway (GO:0001973)2.61601111
102regulation of cholesterol biosynthetic process (GO:0045540)2.61288433
103regulation of early endosome to late endosome transport (GO:2000641)2.60810725
104activation of Rac GTPase activity (GO:0032863)2.60352936
105positive regulation of protein dephosphorylation (GO:0035307)2.60038061
106regulation of synaptic plasticity (GO:0048167)2.59082197
107gamma-aminobutyric acid signaling pathway (GO:0007214)2.58357257
108fatty acid elongation (GO:0030497)2.57500381
109proline metabolic process (GO:0006560)2.57268837
110central nervous system neuron axonogenesis (GO:0021955)2.56768215
111negative regulation of catenin import into nucleus (GO:0035414)2.56734856
112synapse organization (GO:0050808)2.56639915
113neurotransmitter transport (GO:0006836)2.56334015
114positive regulation of dendritic spine development (GO:0060999)2.55255479
115amino acid import (GO:0043090)2.54770729
116regulation of postsynaptic membrane potential (GO:0060078)2.54258443
117positive regulation of dendrite development (GO:1900006)2.54224545
118regulation of dendrite morphogenesis (GO:0048814)2.53885315
119prepulse inhibition (GO:0060134)2.52011863
120neurotransmitter-gated ion channel clustering (GO:0072578)2.49876215
121regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.49726046
122microtubule severing (GO:0051013)2.49644456
123negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.48102557
124regulation of cholesterol homeostasis (GO:2000188)2.47902694
125long-term memory (GO:0007616)2.47149025
126regulation of mammary gland epithelial cell proliferation (GO:0033599)2.47099763
127regulation of neurotransmitter levels (GO:0001505)2.46908698
128female mating behavior (GO:0060180)2.46590188
129regulation of axonogenesis (GO:0050770)2.46340752
130cellular potassium ion homeostasis (GO:0030007)2.44999363
131regulation of chromatin binding (GO:0035561)2.43241928
132phosphatidylglycerol biosynthetic process (GO:0006655)2.43044328
133cell junction maintenance (GO:0034331)2.42717181
134regulation of vesicle fusion (GO:0031338)2.41027465
135regulation of hydrogen peroxide metabolic process (GO:0010310)2.39211681
136respiratory system process (GO:0003016)2.39094258
137protein kinase C signaling (GO:0070528)2.38961393
138adherens junction assembly (GO:0034333)2.35404951
139modulation by virus of host process (GO:0019054)2.34709361
140signal complex assembly (GO:0007172)2.34621311
141negative regulation of dendrite morphogenesis (GO:0050774)2.34587993
142positive regulation of CREB transcription factor activity (GO:0032793)2.34139577
143histone H4 deacetylation (GO:0070933)2.33263240
144regulation of water loss via skin (GO:0033561)2.32903071
145retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.32599444
146regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.29638015
147dicarboxylic acid transport (GO:0006835)2.28759329
148mitochondrion localization (GO:0051646)2.27793991
149adenine nucleotide transport (GO:0051503)2.26419065
150histone H3 deacetylation (GO:0070932)2.25874027
151cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.25595757
152regulation of cholesterol metabolic process (GO:0090181)2.23702472
153negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.23400457
154regulation of regulated secretory pathway (GO:1903305)2.22391337
155pentose-phosphate shunt (GO:0006098)2.19743368

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.49763352
2EZH2_22144423_ChIP-Seq_EOC_Human3.46717091
3VDR_21846776_ChIP-Seq_THP-1_Human3.12111949
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.04838997
5* RARB_27405468_Chip-Seq_BRAIN_Mouse3.01743287
6STAT6_21828071_ChIP-Seq_BEAS2B_Human2.90427163
7ZFP281_18757296_ChIP-ChIP_E14_Mouse2.49635256
8SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.44129495
9TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27517522
10ERG_21242973_ChIP-ChIP_JURKAT_Human2.25550900
11DROSHA_22980978_ChIP-Seq_HELA_Human2.25490416
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.23146601
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20435551
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.18478245
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.14238826
16REST_21632747_ChIP-Seq_MESCs_Mouse2.11196935
17* KDM2B_26808549_Chip-Seq_K562_Human2.07234328
18WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.06588543
19REST_18959480_ChIP-ChIP_MESCs_Mouse2.04634355
20CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.04589324
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04454159
22IKZF1_21737484_ChIP-ChIP_HCT116_Human1.99232712
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.98111745
24TET1_21451524_ChIP-Seq_MESCs_Mouse1.98028070
25SRY_22984422_ChIP-ChIP_TESTIS_Rat1.90230455
26TCF7_22412390_ChIP-Seq_EML_Mouse1.90123918
27SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.89433313
28SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87000289
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.86976697
30TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.86149882
31* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.82487620
32* MYC_22102868_ChIP-Seq_BL_Human1.81079732
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.80120666
34RNF2_18974828_ChIP-Seq_MESCs_Mouse1.80120666
35JARID2_20064375_ChIP-Seq_MESCs_Mouse1.79044184
36ZFP281_27345836_Chip-Seq_ESCs_Mouse1.77391649
37EZH2_27294783_Chip-Seq_ESCs_Mouse1.74643922
38CTCF_27219007_Chip-Seq_ERYTHROID_Human1.74628861
39LXR_22292898_ChIP-Seq_THP-1_Human1.72605795
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.72450410
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.71989237
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.71609272
43DNAJC2_21179169_ChIP-ChIP_NT2_Human1.70547256
44KDM2B_26808549_Chip-Seq_DND41_Human1.70162467
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.68267107
46* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.67817186
47* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.66965700
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.65836286
49JARID2_20075857_ChIP-Seq_MESCs_Mouse1.63289600
50BCOR_27268052_Chip-Seq_Bcells_Human1.61663075
51RNF2_27304074_Chip-Seq_ESCs_Mouse1.61203722
52EZH2_27304074_Chip-Seq_ESCs_Mouse1.61014765
53CTCF_27219007_Chip-Seq_Bcells_Human1.60737481
54BCL6_27268052_Chip-Seq_Bcells_Human1.60130514
55ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.56067457
56ESR2_21235772_ChIP-Seq_MCF-7_Human1.55249556
57TET1_21490601_ChIP-Seq_MESCs_Mouse1.54933955
58RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.53733453
59VDR_24763502_ChIP-Seq_THP-1_Human1.53093232
60* ELF1_20517297_ChIP-Seq_JURKAT_Human1.52961486
61SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.52780960
62ZNF263_19887448_ChIP-Seq_K562_Human1.51615204
63TP63_17297297_ChIP-ChIP_HaCaT_Human1.50658225
64* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.45030392
65CREB1_26743006_Chip-Seq_LNCaP_Human1.41117428
66SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.40008459
67SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.39170022
68TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.38202084
69* RACK7_27058665_Chip-Seq_MCF-7_Human1.36686959
70* E2F1_20622854_ChIP-Seq_HELA_Human1.35290167
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.35284314
72* PHF8_20622854_ChIP-Seq_HELA_Human1.34984833
73P300_27058665_Chip-Seq_ZR-75-30cells_Human1.33854316
74NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.32729418
75SMC4_20622854_ChIP-Seq_HELA_Human1.32229817
76ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.32038150
77SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.31043711
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30788195
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.30082464
80WT1_25993318_ChIP-Seq_PODOCYTE_Human1.28926390
81* MAF_26560356_Chip-Seq_TH2_Human1.28918950
82SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.28357366
83MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.28204953
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.27921010
85RUNX1_27514584_Chip-Seq_MCF-7_Human1.27267326
86RING1B_27294783_Chip-Seq_NPCs_Mouse1.24947979
87RING1B_27294783_Chip-Seq_ESCs_Mouse1.24825795
88OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.23438405
89GBX2_23144817_ChIP-Seq_PC3_Human1.22510552
90ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.22275928
91KDM2B_26808549_Chip-Seq_JURKAT_Human1.22043948
92RARB_24833708_ChIP-Seq_LIVER_Mouse1.21129913
93POU5F1_16518401_ChIP-PET_MESCs_Mouse1.21008305
94KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20343115
95CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.19940559
96* OCT4_19829295_ChIP-Seq_ESCs_Human1.19206515
97RARA_24833708_ChIP-Seq_LIVER_Mouse1.17850312
98ZNF274_21170338_ChIP-Seq_K562_Hela1.15137112
99THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.14940358
100POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14386573
101KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14261927
102KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.14110486
103KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.14110486
104KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.14110486
105NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.14086247
106JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.13150881
107* ELK3_25401928_ChIP-Seq_HUVEC_Human1.13070683
108KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.13025427
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.11717666
110* MAF_26560356_Chip-Seq_TH1_Human1.11104599
111SA1_27219007_Chip-Seq_ERYTHROID_Human1.10421658
112CTCF_21964334_ChIP-Seq_BJAB-B_Human1.09626939
113CTCF_21964334_Chip-Seq_Bcells_Human1.09580757
114FOXP1_21924763_ChIP-Seq_HESCs_Human1.08918554
115* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08916532
116CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.08367888
117KLF4_19829295_ChIP-Seq_ESCs_Human1.08252951
118SA1_27219007_Chip-Seq_Bcells_Human1.08157285
119UTX_26944678_Chip-Seq_JUKART_Human1.08150307
120CTCF_26484167_Chip-Seq_Bcells_Mouse1.07587976
121* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07375278
122* P68_20966046_ChIP-Seq_HELA_Human1.05660859
123PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05202373
124PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04455239
125* TP53_23651856_ChIP-Seq_MEFs_Mouse1.03861662
126CTCF_20526341_ChIP-Seq_ESCs_Human1.03821234
127ETS1_21867929_ChIP-Seq_TH2_Mouse1.03395456
128E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02839501
129* YY1_22570637_ChIP-Seq_MALME-3M_Human1.02064159
130DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02037431
131* GATA1_19941827_ChIP-Seq_MEL_Mouse1.01810005
132SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00934596
133EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00494444
134CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00246505
135ATF3_27146783_Chip-Seq_COLON_Human0.99842295
136NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.99484923
137RXRA_24833708_ChIP-Seq_LIVER_Mouse0.99395004
138NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.99171141
139NCOR1_26117541_ChIP-Seq_K562_Human0.99042813
140EOMES_21245162_ChIP-Seq_HESCs_Human0.97856633
141EED_16625203_ChIP-ChIP_MESCs_Mouse0.95365019
142* TP63_22573176_ChIP-Seq_HFKS_Human0.95268840
143TP53_22127205_ChIP-Seq_IMR90_Human0.92367881
144AR_21572438_ChIP-Seq_LNCaP_Human0.91735282
145CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91250081

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.69392567
2MP0003880_abnormal_central_pattern4.33167945
3MP0004270_analgesia3.84916544
4MP0010234_abnormal_vibrissa_follicle3.78133993
5MP0003635_abnormal_synaptic_transmissio3.32771847
6MP0002064_seizures2.71019926
7MP0003329_amyloid_beta_deposits2.61646704
8MP0004885_abnormal_endolymph2.57490265
9MP0002063_abnormal_learning/memory/cond2.52827308
10MP0003172_abnormal_lysosome_physiology2.40294943
11MP0000778_abnormal_nervous_system2.37292245
12MP0009745_abnormal_behavioral_response2.34898058
13MP0009278_abnormal_bone_marrow2.22839734
14MP0000920_abnormal_myelination2.20059102
15MP0009046_muscle_twitch2.14999500
16MP0001486_abnormal_startle_reflex2.11222063
17MP0002572_abnormal_emotion/affect_behav2.09936343
18MP0002249_abnormal_larynx_morphology2.08385682
19MP0000678_abnormal_parathyroid_gland2.01015810
20MP0003283_abnormal_digestive_organ1.94432229
21MP0000955_abnormal_spinal_cord1.93914903
22MP0001440_abnormal_grooming_behavior1.92173395
23MP0002272_abnormal_nervous_system1.90613870
24MP0000566_synostosis1.88462253
25MP0002733_abnormal_thermal_nociception1.82971231
26MP0008260_abnormal_autophagy1.82094435
27MP0002734_abnormal_mechanical_nocicepti1.78420258
28MP0001188_hyperpigmentation1.73751298
29MP0001968_abnormal_touch/_nociception1.71201831
30MP0005623_abnormal_meninges_morphology1.69475335
31MP0002184_abnormal_innervation1.64855691
32MP0005076_abnormal_cell_differentiation1.64805737
33MP0002822_catalepsy1.64104196
34MP0003634_abnormal_glial_cell1.64025818
35MP0010030_abnormal_orbit_morphology1.63714871
36MP0004858_abnormal_nervous_system1.62609709
37MP0005423_abnormal_somatic_nervous1.60808425
38MP0004811_abnormal_neuron_physiology1.58158656
39MP0003191_abnormal_cellular_cholesterol1.57022609
40MP0004133_heterotaxia1.55673975
41MP0001970_abnormal_pain_threshold1.54745734
42MP0002882_abnormal_neuron_morphology1.49697904
43MP0008569_lethality_at_weaning1.49115536
44MP0003453_abnormal_keratinocyte_physiol1.48933555
45MP0003632_abnormal_nervous_system1.47387300
46MP0002066_abnormal_motor_capabilities/c1.41620510
47MP0003183_abnormal_peptide_metabolism1.41546944
48MP0001529_abnormal_vocalization1.41456683
49MP0010678_abnormal_skin_adnexa1.40214617
50MP0003303_peritoneal_inflammation1.38905301
51MP0003690_abnormal_glial_cell1.38776064
52MP0002796_impaired_skin_barrier1.38017965
53MP0000751_myopathy1.34891156
54MP0005083_abnormal_biliary_tract1.32816094
55MP0002152_abnormal_brain_morphology1.31783314
56MP0009780_abnormal_chondrocyte_physiolo1.31127873
57MP0004185_abnormal_adipocyte_glucose1.29756282
58MP0002653_abnormal_ependyma_morphology1.28926779
59MP0001485_abnormal_pinna_reflex1.28921260
60MP0005666_abnormal_adipose_tissue1.28745069
61MP0004142_abnormal_muscle_tone1.26419305
62MP0005386_behavior/neurological_phenoty1.25476348
63MP0004924_abnormal_behavior1.25476348
64MP0003879_abnormal_hair_cell1.24970622
65MP0003119_abnormal_digestive_system1.24884422
66MP0002067_abnormal_sensory_capabilities1.23808103
67MP0004130_abnormal_muscle_cell1.23560321
68MP0004742_abnormal_vestibular_system1.23522853
69MP0003122_maternal_imprinting1.22915409
70MP0004264_abnormal_extraembryonic_tissu1.22494569
71MP0002229_neurodegeneration1.20583019
72MP0000537_abnormal_urethra_morphology1.19546871
73MP0000681_abnormal_thyroid_gland1.17756157
74MP0003631_nervous_system_phenotype1.15324826
75MP0003861_abnormal_nervous_system1.14724670
76MP0000467_abnormal_esophagus_morphology1.14327105
77MP0000604_amyloidosis1.13297815
78MP0002736_abnormal_nociception_after1.13276273
79MP0004381_abnormal_hair_follicle1.11631583
80MP0001664_abnormal_digestion1.11541176
81MP0001986_abnormal_taste_sensitivity1.10798450
82MP0001765_abnormal_ion_homeostasis1.07870904
83MP0003633_abnormal_nervous_system1.04675452
84MP0002557_abnormal_social/conspecific_i1.02951763
85MP0000747_muscle_weakness1.02552825
86MP0001348_abnormal_lacrimal_gland1.02208600
87MP0005377_hearing/vestibular/ear_phenot1.01138136
88MP0003878_abnormal_ear_physiology1.01138136
89MP0001849_ear_inflammation1.01066845
90MP0004233_abnormal_muscle_weight1.00093698
91MP0005375_adipose_tissue_phenotype0.97857706
92MP0000462_abnormal_digestive_system0.94744613
93MP0003123_paternal_imprinting0.94742980
94MP0009840_abnormal_foam_cell0.91148465
95MP0002098_abnormal_vibrissa_morphology0.91077593
96MP0003436_decreased_susceptibility_to0.90538673
97MP0002752_abnormal_somatic_nervous0.90082510
98MP0009379_abnormal_foot_pigmentation0.86767028
99MP0002735_abnormal_chemical_nociception0.86694068
100MP0009931_abnormal_skin_appearance0.86403841
101MP0003938_abnormal_ear_development0.85153886
102MP0000534_abnormal_ureter_morphology0.84939180
103MP0005535_abnormal_body_temperature0.82234213
104MP0002089_abnormal_postnatal_growth/wei0.82182504
105MP0000013_abnormal_adipose_tissue0.81552829
106MP0002090_abnormal_vision0.80730918
107MP0002234_abnormal_pharynx_morphology0.79845461
108MP0008961_abnormal_basal_metabolism0.79723600
109MP0004782_abnormal_surfactant_physiolog0.79630755
110MP0001905_abnormal_dopamine_level0.78586636
111MP0001501_abnormal_sleep_pattern0.77752427
112MP0005058_abnormal_lysosome_morphology0.77671126
113MP0010771_integument_phenotype0.77484104
114MP0003787_abnormal_imprinting0.77282873
115MP0000750_abnormal_muscle_regeneration0.76887326
116MP0005501_abnormal_skin_physiology0.75456793
117MP0005646_abnormal_pituitary_gland0.73790777
118MP0004947_skin_inflammation0.72313454
119MP0000538_abnormal_urinary_bladder0.72139234
120MP0005670_abnormal_white_adipose0.71501303
121MP0005645_abnormal_hypothalamus_physiol0.70956227
122MP0003075_altered_response_to0.70845093
123MP0003705_abnormal_hypodermis_morpholog0.69682292
124MP0000579_abnormal_nail_morphology0.68340463
125MP0001545_abnormal_hematopoietic_system0.67381363
126MP0005397_hematopoietic_system_phenotyp0.67381363
127MP0003385_abnormal_body_wall0.67115555
128MP0005174_abnormal_tail_pigmentation0.66372445
129MP0005394_taste/olfaction_phenotype0.65915820
130MP0005499_abnormal_olfactory_system0.65915820
131MP0001730_embryonic_growth_arrest0.65532890
132MP0008770_decreased_survivor_rate0.64264137
133MP0001502_abnormal_circadian_rhythm0.64204760
134MP0010769_abnormal_survival0.63569170
135MP0002909_abnormal_adrenal_gland0.63424430
136MP0008874_decreased_physiological_sensi0.62343456
137MP0002084_abnormal_developmental_patter0.62224078
138MP0010768_mortality/aging0.61997588
139MP0010352_gastrointestinal_tract_polyps0.60751635
140MP0001340_abnormal_eyelid_morphology0.60519139
141MP0000003_abnormal_adipose_tissue0.59903413
142MP0005409_darkened_coat_color0.59804781
143MP0002751_abnormal_autonomic_nervous0.59175911
144MP0002085_abnormal_embryonic_tissue0.57734785
145MP0005171_absent_coat_pigmentation0.57686718
146MP0005451_abnormal_body_composition0.57574291

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.82887953
2Neurofibrillary tangles (HP:0002185)4.62849606
3Supranuclear gaze palsy (HP:0000605)4.60240338
4Cerebral inclusion bodies (HP:0100314)4.27510124
5Focal seizures (HP:0007359)3.90938727
6Thin bony cortex (HP:0002753)3.84772655
7Visual hallucinations (HP:0002367)3.78640614
8Focal motor seizures (HP:0011153)3.74374810
9Cerebral hypomyelination (HP:0006808)3.43674165
10Turricephaly (HP:0000262)3.31760045
11Abnormality of the corticospinal tract (HP:0002492)3.12869186
12Ankle clonus (HP:0011448)3.08462630
13Hemorrhage of the eye (HP:0011885)3.07050606
14Spastic gait (HP:0002064)3.05908403
15Intention tremor (HP:0002080)3.00258431
16Dialeptic seizures (HP:0011146)2.98430898
17Testicular atrophy (HP:0000029)2.97794317
18Myopathic facies (HP:0002058)2.96851939
19Ulnar bowing (HP:0003031)2.91727375
20Absence seizures (HP:0002121)2.89610214
21Dysmetria (HP:0001310)2.87837987
22Stridor (HP:0010307)2.81524308
23Abnormality of the lower motor neuron (HP:0002366)2.81364114
24Akinesia (HP:0002304)2.80376987
25Degeneration of the lateral corticospinal tracts (HP:0002314)2.78908418
26Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.78908418
27Insomnia (HP:0100785)2.77394964
28Anteriorly placed anus (HP:0001545)2.62530589
29Atonic seizures (HP:0010819)2.61727515
30Mutism (HP:0002300)2.60433396
31Overriding aorta (HP:0002623)2.57146042
32Urinary urgency (HP:0000012)2.52675198
33Hand muscle atrophy (HP:0009130)2.52593789
34Neonatal onset (HP:0003623)2.51869099
35Ependymoma (HP:0002888)2.50882464
36Split foot (HP:0001839)2.48840033
37Astrocytoma (HP:0009592)2.46039276
38Abnormality of the astrocytes (HP:0100707)2.46039276
39Broad face (HP:0000283)2.44703387
40Torticollis (HP:0000473)2.43590611
41Dysdiadochokinesis (HP:0002075)2.40122647
42Clumsiness (HP:0002312)2.37697816
43Neuronal loss in central nervous system (HP:0002529)2.36621003
44Hyperthyroidism (HP:0000836)2.36422374
45Rapidly progressive (HP:0003678)2.35519996
46Achilles tendon contracture (HP:0001771)2.34819372
47Amyotrophic lateral sclerosis (HP:0007354)2.34529683
48Abnormality of the aortic arch (HP:0012303)2.31834250
49Peripheral hypomyelination (HP:0007182)2.30621880
50Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.29574760
51Neoplasm of the heart (HP:0100544)2.29110498
52Postural instability (HP:0002172)2.28695224
53Distal lower limb amyotrophy (HP:0008944)2.27356117
54Spastic tetraparesis (HP:0001285)2.26622576
55Sensory axonal neuropathy (HP:0003390)2.23727608
56Germ cell neoplasia (HP:0100728)2.21108613
57Long palpebral fissure (HP:0000637)2.20721300
58Aplasia of the phalanges of the hand (HP:0009802)2.18985623
59Aplasia involving bones of the extremities (HP:0009825)2.18985623
60Aplasia involving bones of the upper limbs (HP:0009823)2.18985623
61Increased cerebral lipofuscin (HP:0011813)2.18577510
62CNS hypomyelination (HP:0003429)2.16773443
63Cerebral aneurysm (HP:0004944)2.16365981
64Stenosis of the external auditory canal (HP:0000402)2.16170050
65Annular pancreas (HP:0001734)2.15054219
66Renal duplication (HP:0000075)2.14194823
67Atelectasis (HP:0100750)2.13492459
68Insidious onset (HP:0003587)2.12988800
69Termporal pattern (HP:0011008)2.12988800
70Bronchomalacia (HP:0002780)2.12606147
71Pointed chin (HP:0000307)2.12087965
72Hypercortisolism (HP:0001578)2.11406665
73Hyperacusis (HP:0010780)2.11243957
74Hypoplastic nipples (HP:0002557)2.11242955
75Onion bulb formation (HP:0003383)2.10723239
76Abnormality of the Achilles tendon (HP:0005109)2.10086555
77Spinal canal stenosis (HP:0003416)2.09474106
78Generalized tonic-clonic seizures (HP:0002069)2.09242397
79Abnormality of binocular vision (HP:0011514)2.09118549
80Diplopia (HP:0000651)2.09118549
81Distal lower limb muscle weakness (HP:0009053)2.08453782
82Action tremor (HP:0002345)2.07456370
83Mesangial abnormality (HP:0001966)2.06751488
84Hyperparathyroidism (HP:0000843)2.04784198
85Epileptic encephalopathy (HP:0200134)2.03025285
86Easy fatigability (HP:0003388)2.02825105
87Apathy (HP:0000741)2.02425363
88Growth hormone excess (HP:0000845)2.02422384
89Megalencephaly (HP:0001355)2.02183270
90Global brain atrophy (HP:0002283)2.01068429
91Morphological abnormality of the pyramidal tract (HP:0002062)2.00788412
92Clonus (HP:0002169)1.99879546
93Lymphangioma (HP:0100764)1.98290131
94Lower limb amyotrophy (HP:0007210)1.98205040
95Hyporeflexia of lower limbs (HP:0002600)1.96763206
96J-shaped sella turcica (HP:0002680)1.95903741
97Lower limb muscle weakness (HP:0007340)1.93843166
98Deep palmar crease (HP:0006191)1.93416005
99Athetosis (HP:0002305)1.92718751
100Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.91970003
101Arnold-Chiari malformation (HP:0002308)1.91836691
102Diminished motivation (HP:0000745)1.91391140
103Obstructive sleep apnea (HP:0002870)1.91078427
104Craniofacial dystonia (HP:0012179)1.90787688
105Focal dystonia (HP:0004373)1.90434852
106Depression (HP:0000716)1.90403009
107Increased neuronal autofluorescent lipopigment (HP:0002074)1.88716984
108Sleep apnea (HP:0010535)1.86789724
109Increased IgE level (HP:0003212)1.86451402
110Bowel incontinence (HP:0002607)1.86155212
111Polygenic inheritance (HP:0010982)1.85934570
112Abnormality of mucopolysaccharide metabolism (HP:0011020)1.85505978
113Abnormality of polysaccharide metabolism (HP:0011012)1.85505978
114Abnormality of glycosaminoglycan metabolism (HP:0004371)1.85505978
115Broad distal phalanx of finger (HP:0009836)1.85325396
116Truncal ataxia (HP:0002078)1.84732906
117Abnormal eating behavior (HP:0100738)1.84539804
118Abnormal atrioventricular conduction (HP:0005150)1.84456654
119Alacrima (HP:0000522)1.84135197
120Abnormal social behavior (HP:0012433)1.83847989
121Impaired social interactions (HP:0000735)1.83847989
122Joint stiffness (HP:0001387)1.83481669
123Scanning speech (HP:0002168)1.83264275
124Eczematoid dermatitis (HP:0000976)1.82794900
125Coronal craniosynostosis (HP:0004440)1.82531681
126Abnormality of the labia minora (HP:0012880)1.82403647
127Ventricular fibrillation (HP:0001663)1.80954116
128Ragged-red muscle fibers (HP:0003200)1.80620904
129Dysostosis multiplex (HP:0000943)1.79988410
130Nasal polyposis (HP:0100582)1.78744564
131Impaired vibration sensation in the lower limbs (HP:0002166)1.78690301
132Broad-based gait (HP:0002136)1.78137178
133Supernumerary nipples (HP:0002558)1.78083614
134Precocious puberty (HP:0000826)1.76933166
135Stereotypic behavior (HP:0000733)1.76915094
136Mucopolysacchariduria (HP:0008155)1.76758189
137Urinary glycosaminoglycan excretion (HP:0003541)1.76758189
138Hemiparesis (HP:0001269)1.74884099
139Delayed epiphyseal ossification (HP:0002663)1.74629759
140Abnormal large intestine physiology (HP:0012700)1.74615791
141Upper limb amyotrophy (HP:0009129)1.74203495
142Distal upper limb amyotrophy (HP:0007149)1.74203495
143Hamartoma of the eye (HP:0010568)1.74150680
144Generalized myoclonic seizures (HP:0002123)1.73730792
145Rib fusion (HP:0000902)1.73628709
146Lower limb asymmetry (HP:0100559)1.73530172
147Truncus arteriosus (HP:0001660)1.73400483
148Ankyloglossia (HP:0010296)1.73126491
149Macroorchidism (HP:0000053)1.73081010
150Loss of speech (HP:0002371)1.72906400
151Difficulty running (HP:0009046)1.72725401
152Aqueductal stenosis (HP:0002410)1.72358251
153Hypoplastic pelvis (HP:0008839)1.72339068
154Heart block (HP:0012722)1.72146706
155Reticulocytosis (HP:0001923)1.71592886
156Distal sensory impairment (HP:0002936)1.71587059
157Abnormality of the nasal mucosa (HP:0000433)1.71289858
158Urinary bladder sphincter dysfunction (HP:0002839)1.71036386
159Atrioventricular block (HP:0001678)1.70125862
160Flattened epiphyses (HP:0003071)1.69904997
161Thin ribs (HP:0000883)1.69828470
162Abnormality of the fingertips (HP:0001211)1.69531621
163External ophthalmoplegia (HP:0000544)1.69006762
164Dementia (HP:0000726)1.68686793
165Fetal akinesia sequence (HP:0001989)1.66931913

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK4.35657156
2NTRK33.93330137
3MAP3K93.82533413
4EPHA43.52948354
5SIK13.12081078
6TYRO32.76142233
7MARK12.75784922
8ICK2.61265410
9ERN12.57536731
10SMG12.47559797
11MAPK152.42369682
12KSR22.39863487
13STK392.15407850
14PAK62.14524573
15PRPF4B2.11129645
16RIPK12.10433594
17PRKD31.90056428
18CDK191.77228901
19FGFR21.73857322
20EEF2K1.73679792
21KSR11.72723944
22DAPK21.72142600
23LATS21.71897456
24TESK11.67559453
25OXSR11.65969984
26TAOK11.60104063
27RIPK41.55760734
28MINK11.53646404
29NTRK11.50742269
30ARAF1.48098780
31TNK21.46832607
32MAP2K31.43205198
33LIMK11.38918042
34NTRK21.35817498
35TRIB31.29214582
36EPHB11.25931992
37MARK21.24791454
38UHMK11.24336770
39CDK51.18607832
40STK111.18085274
41MAP3K21.13545125
42CSNK1G21.13441005
43ALK1.12292416
44CSNK1A1L1.08285001
45PHKG11.05604377
46PHKG21.05604377
47CSNK1G31.05217421
48NME21.03205462
49DYRK1B1.02830530
50PAK31.00723871
51WNK11.00528040
52IRAK31.00184402
53BCR0.98928029
54CDK140.97948890
55PKN10.97927653
56SIK20.97234618
57FES0.96882384
58PTK60.96767702
59CDK150.94828574
60MET0.92534714
61CDK180.91912059
62PNCK0.91126723
63RPS6KC10.90650546
64RPS6KL10.90650546
65CAMKK10.90487228
66MST1R0.89094357
67STK380.88937347
68MAP2K20.85823139
69CDK11A0.85676324
70MAP3K40.82974342
71GRK60.82161872
72MAP2K40.80113014
73MAPK120.78462446
74ROCK20.78383213
75FGR0.77946638
76MAP2K60.76978302
77MAP3K30.76894359
78CSNK1G10.76778027
79CAMK10.74196357
80TBK10.72624369
81NME10.71931204
82RPS6KA60.70436159
83MAPK130.70281854
84BRAF0.69981979
85MUSK0.69135116
86FGFR40.68855428
87PRKCH0.67904514
88MAP4K10.67696401
89PRKG20.67658773
90DDR20.66333429
91FER0.65706074
92CAMK2B0.65702071
93PIM20.65049166
94LRRK20.64343495
95DYRK20.64305025
96DAPK30.63788672
97LMTK20.63009391
98DAPK10.62696102
99PDPK10.62020119
100IRAK20.61721157
101RET0.61704516
102PTK20.61636523
103RAF10.61254859
104MAP3K110.61135169
105EPHA20.61129874
106HIPK20.60449296
107PKN20.59297816
108CDK120.58340415
109GRK50.57535512
110WNK40.56633937
111SIK30.56077722
112MAPK100.56067423
113PRKD20.53803334
114TAOK20.53637539
115NEK60.52830519
116CAMK2A0.52097685
117MAP3K130.51798489
118CAMK40.51558617
119SCYL20.51314753
120CSNK1E0.50947963
121MAP3K70.50140483
122PRKCG0.49308385
123EPHB20.48665443
124PDGFRA0.48600007
125PRKD10.47368791
126CSNK1D0.46441999
127MTOR0.46386482
128PAK10.46355992
129RPS6KA20.46286194
130MAP3K60.43460277
131BMX0.42446971
132MAPK80.41829040
133MAP3K10.40877179
134PRKCI0.40788004
135TESK20.40692975
136CAMK2G0.38534052
137PAK20.38266669
138PDGFRB0.37945487
139PRKCZ0.36643315
140FYN0.36334822
141PDK10.35629495
142CDC42BPA0.35156117

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.64689367
2Synaptic vesicle cycle_Homo sapiens_hsa047212.59303006
3Nicotine addiction_Homo sapiens_hsa050332.35665895
4Axon guidance_Homo sapiens_hsa043602.26432727
5Long-term potentiation_Homo sapiens_hsa047202.23842929
6Glutamatergic synapse_Homo sapiens_hsa047242.12715094
7Sulfur relay system_Homo sapiens_hsa041222.04534998
8GABAergic synapse_Homo sapiens_hsa047271.98574310
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.88974704
10Fructose and mannose metabolism_Homo sapiens_hsa000511.84303202
11Amphetamine addiction_Homo sapiens_hsa050311.83644487
12Other glycan degradation_Homo sapiens_hsa005111.78134013
13Olfactory transduction_Homo sapiens_hsa047401.78100526
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.75336012
15Circadian entrainment_Homo sapiens_hsa047131.72621288
16Dopaminergic synapse_Homo sapiens_hsa047281.72288074
17Morphine addiction_Homo sapiens_hsa050321.71855189
18ErbB signaling pathway_Homo sapiens_hsa040121.59502869
19VEGF signaling pathway_Homo sapiens_hsa043701.56251128
20Gap junction_Homo sapiens_hsa045401.54533502
21Cocaine addiction_Homo sapiens_hsa050301.45226803
22Glioma_Homo sapiens_hsa052141.42470249
23Gastric acid secretion_Homo sapiens_hsa049711.41877068
24Nitrogen metabolism_Homo sapiens_hsa009101.41442764
25Long-term depression_Homo sapiens_hsa047301.41141881
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.37668395
27Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.36842047
28Acute myeloid leukemia_Homo sapiens_hsa052211.36364994
29Salivary secretion_Homo sapiens_hsa049701.35407271
30GnRH signaling pathway_Homo sapiens_hsa049121.34029653
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.33964890
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.33012957
33Carbohydrate digestion and absorption_Homo sapiens_hsa049731.32079333
34Oxytocin signaling pathway_Homo sapiens_hsa049211.30751233
35Cholinergic synapse_Homo sapiens_hsa047251.30333911
36Estrogen signaling pathway_Homo sapiens_hsa049151.29227597
37Phospholipase D signaling pathway_Homo sapiens_hsa040721.28262592
38Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.28123584
39Cyanoamino acid metabolism_Homo sapiens_hsa004601.27854620
40Choline metabolism in cancer_Homo sapiens_hsa052311.23536033
41Melanogenesis_Homo sapiens_hsa049161.22537485
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22156276
43Hedgehog signaling pathway_Homo sapiens_hsa043401.21672376
44Endocytosis_Homo sapiens_hsa041441.21517385
45Aldosterone synthesis and secretion_Homo sapiens_hsa049251.20872680
46Renal cell carcinoma_Homo sapiens_hsa052111.20342598
47Oocyte meiosis_Homo sapiens_hsa041141.19674340
48Pentose phosphate pathway_Homo sapiens_hsa000301.17937148
49Vitamin B6 metabolism_Homo sapiens_hsa007501.15344127
50Endometrial cancer_Homo sapiens_hsa052131.13673520
51Dorso-ventral axis formation_Homo sapiens_hsa043201.12269720
52Basal cell carcinoma_Homo sapiens_hsa052171.11515263
53Central carbon metabolism in cancer_Homo sapiens_hsa052301.11121899
54Hippo signaling pathway_Homo sapiens_hsa043901.10985154
55Insulin secretion_Homo sapiens_hsa049111.09607751
56mTOR signaling pathway_Homo sapiens_hsa041501.09169248
57Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08812922
58Tight junction_Homo sapiens_hsa045301.06692340
59Renin secretion_Homo sapiens_hsa049241.06333261
60Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.04371059
61Sphingolipid signaling pathway_Homo sapiens_hsa040711.03654778
62Collecting duct acid secretion_Homo sapiens_hsa049661.03425075
63Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03345127
64Calcium signaling pathway_Homo sapiens_hsa040201.03142879
65Vibrio cholerae infection_Homo sapiens_hsa051101.02554520
66AMPK signaling pathway_Homo sapiens_hsa041521.02463838
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99690160
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98307824
69Serotonergic synapse_Homo sapiens_hsa047260.96875706
70Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.96349928
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.95433427
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.93579144
73Phenylalanine metabolism_Homo sapiens_hsa003600.92356228
74Taste transduction_Homo sapiens_hsa047420.91495224
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90548340
76Wnt signaling pathway_Homo sapiens_hsa043100.89350378
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.88843263
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.87181365
79cAMP signaling pathway_Homo sapiens_hsa040240.86674436
80Steroid biosynthesis_Homo sapiens_hsa001000.86302323
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82608930
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80251540
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.79533036
84Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.77383579
85Arginine biosynthesis_Homo sapiens_hsa002200.77223389
86Ether lipid metabolism_Homo sapiens_hsa005650.77218449
87MAPK signaling pathway_Homo sapiens_hsa040100.76565481
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76446094
89Ras signaling pathway_Homo sapiens_hsa040140.75185967
90Galactose metabolism_Homo sapiens_hsa000520.74623476
91Prion diseases_Homo sapiens_hsa050200.74321613
92Biosynthesis of amino acids_Homo sapiens_hsa012300.73148766
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.72954608
94cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71790404
95Bile secretion_Homo sapiens_hsa049760.70958623
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70810840
97Colorectal cancer_Homo sapiens_hsa052100.70676135
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70675759
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69003654
100Insulin resistance_Homo sapiens_hsa049310.67281268
101Glucagon signaling pathway_Homo sapiens_hsa049220.66143779
102Hepatitis C_Homo sapiens_hsa051600.64877935
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.64549725
104Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.64291651
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62359272
106B cell receptor signaling pathway_Homo sapiens_hsa046620.62166236
107Pancreatic secretion_Homo sapiens_hsa049720.61448216
108Sphingolipid metabolism_Homo sapiens_hsa006000.60155794
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.59051496
110Rap1 signaling pathway_Homo sapiens_hsa040150.58884921
111Inositol phosphate metabolism_Homo sapiens_hsa005620.57257686
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56662373
113Non-small cell lung cancer_Homo sapiens_hsa052230.55846232
114Lysosome_Homo sapiens_hsa041420.54528017
115Pancreatic cancer_Homo sapiens_hsa052120.53968639
116Bladder cancer_Homo sapiens_hsa052190.52760705
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51927683
118Insulin signaling pathway_Homo sapiens_hsa049100.51289560
119Type II diabetes mellitus_Homo sapiens_hsa049300.50624062
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.50141076
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49434286
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49411075
123Proteoglycans in cancer_Homo sapiens_hsa052050.47553887
124Chronic myeloid leukemia_Homo sapiens_hsa052200.47159933
125Ovarian steroidogenesis_Homo sapiens_hsa049130.47117039
126Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45974272
127Fatty acid elongation_Homo sapiens_hsa000620.45939294
128Notch signaling pathway_Homo sapiens_hsa043300.44044674
129Cardiac muscle contraction_Homo sapiens_hsa042600.42717108

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