RAB44

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1defense response to fungus (GO:0050832)6.49525894
2killing of cells in other organism involved in symbiotic interaction (GO:0051883)6.38227195
3disruption of cells of other organism involved in symbiotic interaction (GO:0051818)6.38227195
4neutrophil mediated immunity (GO:0002446)6.27865368
5response to fungus (GO:0009620)6.16325179
6positive regulation of gamma-delta T cell activation (GO:0046645)5.89219416
7negative regulation of phagocytosis (GO:0050765)5.76738862
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.48195723
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.48195723
10negative regulation of erythrocyte differentiation (GO:0045647)5.32725331
11pentose-phosphate shunt (GO:0006098)5.27719977
12positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)5.24187257
13ribosomal small subunit assembly (GO:0000028)5.05546437
14respiratory burst (GO:0045730)4.82381170
15NADPH regeneration (GO:0006740)4.82017279
16myeloid leukocyte mediated immunity (GO:0002444)4.79592533
17detection of other organism (GO:0098543)4.79301253
18killing of cells of other organism (GO:0031640)4.74177357
19disruption of cells of other organism (GO:0044364)4.74177357
20detection of bacterium (GO:0016045)4.66245268
21negative regulation of interleukin-8 production (GO:0032717)4.60693278
22antigen processing and presentation of endogenous antigen (GO:0019883)4.45048380
23modulation of growth of symbiont involved in interaction with host (GO:0044144)4.42420191
24regulation of growth of symbiont in host (GO:0044126)4.42420191
25negative regulation of growth of symbiont in host (GO:0044130)4.42420191
26negative regulation of growth of symbiont involved in interaction with host (GO:0044146)4.42420191
27response to peptidoglycan (GO:0032494)4.40916387
28positive regulation of mast cell degranulation (GO:0043306)4.36395094
29positive regulation of mast cell activation involved in immune response (GO:0033008)4.36395094
30positive regulation of mast cell activation (GO:0033005)4.30654399
31modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.29453140
32positive regulation by organism of defense response of other organism involved in symbiotic interact4.29453140
33modulation by symbiont of host immune response (GO:0052553)4.29453140
34positive regulation by symbiont of host defense response (GO:0052509)4.29453140
35modulation by symbiont of host defense response (GO:0052031)4.29453140
36modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.29453140
37leukotriene biosynthetic process (GO:0019370)4.25428736
38microglial cell activation (GO:0001774)4.20484327
39leukocyte aggregation (GO:0070486)4.13196887
40regulation of B cell differentiation (GO:0045577)4.09594899
41regulation of gamma-delta T cell activation (GO:0046643)4.02840751
42regulation of B cell receptor signaling pathway (GO:0050855)3.97492361
43regulation of mast cell degranulation (GO:0043304)3.93255652
44Arp2/3 complex-mediated actin nucleation (GO:0034314)3.92132111
45neutrophil activation involved in immune response (GO:0002283)3.90847129
46DNA unwinding involved in DNA replication (GO:0006268)3.90521950
47negative regulation of cell killing (GO:0031342)3.85180572
48negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.85180572
49regulation of interleukin-8 biosynthetic process (GO:0045414)3.82688157
50regulation of gamma-delta T cell differentiation (GO:0045586)3.82558887
51megakaryocyte development (GO:0035855)3.81417498
52glucose 6-phosphate metabolic process (GO:0051156)3.80183919
53leukocyte migration involved in inflammatory response (GO:0002523)3.79288314
54DNA strand elongation involved in DNA replication (GO:0006271)3.76775116
55granulocyte activation (GO:0036230)3.76503726
56reactive oxygen species biosynthetic process (GO:1903409)3.75648059
57B cell receptor signaling pathway (GO:0050853)3.73137464
58leukotriene metabolic process (GO:0006691)3.72828571
59production of molecular mediator involved in inflammatory response (GO:0002532)3.71408043
60regulation of mast cell activation (GO:0033003)3.70741616
61DNA deamination (GO:0045006)3.70140035
62macrophage differentiation (GO:0030225)3.67976035
63protein localization to kinetochore (GO:0034501)3.67767105
64viral transcription (GO:0019083)3.67459204
65positive regulation of granulocyte differentiation (GO:0030854)3.63534262
66telomere maintenance via semi-conservative replication (GO:0032201)3.63032608
67regulation of myeloid leukocyte mediated immunity (GO:0002886)3.62976695
68DNA strand elongation (GO:0022616)3.62325501
69regulation of mast cell activation involved in immune response (GO:0033006)3.61288008
70antigen processing and presentation via MHC class Ib (GO:0002475)3.61160904
71definitive hemopoiesis (GO:0060216)3.60395741
72detection of external biotic stimulus (GO:0098581)3.57583182
73sequestering of metal ion (GO:0051238)3.56819052
74antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.54997530
75glucose catabolic process (GO:0006007)3.54651798
76cellular extravasation (GO:0045123)3.54528103
77myeloid cell activation involved in immune response (GO:0002275)3.53062203
78pentose metabolic process (GO:0019321)3.52953349
79angiotensin maturation (GO:0002003)3.52867056
80innate immune response in mucosa (GO:0002227)3.52244257
81response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.52089412
82response to host immune response (GO:0052572)3.52089412
83macrophage activation involved in immune response (GO:0002281)3.51343211
84leukocyte mediated cytotoxicity (GO:0001909)3.50499309
85translational termination (GO:0006415)3.50419212
86regulation of hypersensitivity (GO:0002883)3.49846849
87negative regulation of interleukin-12 production (GO:0032695)3.48472993
88regulation of leukocyte degranulation (GO:0043300)3.45197185
89macrophage activation (GO:0042116)3.45132556
90negative regulation of interleukin-6 production (GO:0032715)3.44652977
91lipoxygenase pathway (GO:0019372)3.41797563
92SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.41114675
93regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.38783768
94positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.37426634
95positive regulation of B cell differentiation (GO:0045579)3.36100791
96negative regulation of T cell mediated immunity (GO:0002710)3.35002136
97detection of biotic stimulus (GO:0009595)3.34626479
98cotranslational protein targeting to membrane (GO:0006613)3.33241767
99protein targeting to ER (GO:0045047)3.32746973
100cell wall macromolecule catabolic process (GO:0016998)3.28618193
101negative regulation of lymphocyte mediated immunity (GO:0002707)3.25556401
102immunoglobulin mediated immune response (GO:0016064)3.25246115
103regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.24519008
104mast cell activation (GO:0045576)3.21882055
105response to muramyl dipeptide (GO:0032495)3.21608590
106establishment of protein localization to endoplasmic reticulum (GO:0072599)3.18406199
107response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.16473432
108response to host (GO:0075136)3.16473432
109response to host defenses (GO:0052200)3.16473432
110protein localization to chromosome, centromeric region (GO:0071459)3.16231415
111T cell migration (GO:0072678)3.15910485
112DNA replication initiation (GO:0006270)3.15436928
113translational elongation (GO:0006414)3.13527988
114regulation of chemokine biosynthetic process (GO:0045073)3.12683582
115protein localization to endoplasmic reticulum (GO:0070972)3.12442896
116IMP metabolic process (GO:0046040)3.08813217
117G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.06320124
118actin nucleation (GO:0045010)3.05326058
119telomere maintenance via recombination (GO:0000722)3.04996526
120regulation of MHC class II biosynthetic process (GO:0045346)3.04511610
121organ or tissue specific immune response (GO:0002251)3.02762683
122positive regulation of leukocyte degranulation (GO:0043302)3.02515162
123negative regulation of leukocyte mediated immunity (GO:0002704)3.01386196
124neutrophil activation (GO:0042119)3.00621475
125positive thymic T cell selection (GO:0045059)3.00502306
126regulation of granulocyte differentiation (GO:0030852)3.00464968
127regulation of regulated secretory pathway (GO:1903305)3.00375313
128L-fucose catabolic process (GO:0042355)3.00360426
129fucose catabolic process (GO:0019317)3.00360426
130L-fucose metabolic process (GO:0042354)3.00360426
131poly(A)+ mRNA export from nucleus (GO:0016973)2.97659559
132mast cell activation involved in immune response (GO:0002279)2.97327273
133mast cell degranulation (GO:0043303)2.97327273
134ribosomal small subunit biogenesis (GO:0042274)2.97106997
135mucosal immune response (GO:0002385)2.95705567
136leukocyte degranulation (GO:0043299)2.95384918
137positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.94221955
138positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.94146116
139antibacterial humoral response (GO:0019731)2.93764942
140pinocytosis (GO:0006907)2.92968087
1413-UTR-mediated mRNA stabilization (GO:0070935)2.87499856
142negative regulation of granulocyte differentiation (GO:0030853)2.85214808
143positive regulation of tumor necrosis factor production (GO:0032760)2.84098239
144defense response to Gram-positive bacterium (GO:0050830)2.83167827
145mitotic recombination (GO:0006312)2.83047934
146antimicrobial humoral response (GO:0019730)2.81640108
147positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.81151447
148cellular response to zinc ion (GO:0071294)2.77324726
149cellular protein complex disassembly (GO:0043624)2.76717295
150nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.76455734
151DNA topological change (GO:0006265)2.76322315
152DNA replication checkpoint (GO:0000076)2.76217325
153angiogenesis involved in wound healing (GO:0060055)2.74044547
154IMP biosynthetic process (GO:0006188)2.72630523
155thrombin receptor signaling pathway (GO:0070493)2.72321135
156negative regulation of RNA splicing (GO:0033119)2.71915635
157viral life cycle (GO:0019058)2.70819975
158mannose metabolic process (GO:0006013)2.69035589

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.65729617
2BP1_19119308_ChIP-ChIP_Hs578T_Human3.73827089
3MYB_21317192_ChIP-Seq_ERMYB_Mouse3.63387533
4VDR_21846776_ChIP-Seq_THP-1_Human3.50494419
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.44371079
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.30640041
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.27936380
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.26726497
9SCL_19346495_ChIP-Seq_HPC-7_Human2.82714237
10E2F4_17652178_ChIP-ChIP_JURKAT_Human2.76831565
11MYC_22102868_ChIP-Seq_BL_Human2.66527990
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.64879072
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.51791290
14RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.42668265
15SPI1_23547873_ChIP-Seq_NB4_Human2.35834568
16VDR_24763502_ChIP-Seq_THP-1_Human2.30454470
17BRD4_27068464_Chip-Seq_AML-cells_Mouse2.28677686
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.24876285
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.20952007
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.20811298
21VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.13972017
22TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.11895030
23SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.06521162
24* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.02144129
25RUNX1_22412390_ChIP-Seq_EML_Mouse1.99432518
26IRF8_21731497_ChIP-ChIP_J774_Mouse1.98988976
27ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.95134894
28SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.91758884
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.90989844
30NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.90335596
31KDM2B_26808549_Chip-Seq_DND41_Human1.89042944
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.88349724
33KDM2B_26808549_Chip-Seq_SUP-B15_Human1.85575428
34STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.84351305
35SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.81651925
36VDR_24787735_ChIP-Seq_THP-1_Human1.80492077
37RUNX_20019798_ChIP-Seq_JUKART_Human1.79771465
38KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.75379338
39NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.73854191
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73475366
41IRF8_22096565_ChIP-ChIP_GC-B_Human1.73107707
42IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.72548372
43UTX_26944678_Chip-Seq_JUKART_Human1.70554159
44MYC_18358816_ChIP-ChIP_MESCs_Mouse1.68861560
45MYB_26560356_Chip-Seq_TH2_Human1.65986323
46MAF_26560356_Chip-Seq_TH1_Human1.65324950
47CIITA_25753668_ChIP-Seq_RAJI_Human1.64952611
48TCF7_22412390_ChIP-Seq_EML_Mouse1.62450871
49E2F1_21310950_ChIP-Seq_MCF-7_Human1.60643208
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.60047185
51HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.59685403
52MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.59338658
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.59107735
54GATA1_22383799_ChIP-Seq_G1ME_Mouse1.57777767
55XRN2_22483619_ChIP-Seq_HELA_Human1.56650901
56STAT4_19710469_ChIP-ChIP_TH1__Mouse1.55544601
57MYB_26560356_Chip-Seq_TH1_Human1.54300601
58MYC_19079543_ChIP-ChIP_MESCs_Mouse1.53509039
59IRF8_27001747_Chip-Seq_BMDM_Mouse1.53422401
60MYC_19030024_ChIP-ChIP_MESCs_Mouse1.49526707
61GATA1_19941826_ChIP-Seq_K562_Human1.47199538
62LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.45614065
63GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.45569472
64ETS1_20019798_ChIP-Seq_JURKAT_Human1.45295853
65GABP_17652178_ChIP-ChIP_JURKAT_Human1.45212749
66LXR_22292898_ChIP-Seq_THP-1_Human1.44592748
67KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.44349454
68FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.43327195
69FOXP3_21729870_ChIP-Seq_TREG_Human1.42602558
70VDR_23849224_ChIP-Seq_CD4+_Human1.41308396
71GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.40194930
72GATA1_22025678_ChIP-Seq_K562_Human1.39231417
73GATA3_27048872_Chip-Seq_THYMUS_Human1.38369137
74GATA2_22383799_ChIP-Seq_G1ME_Mouse1.33431720
75AR_21909140_ChIP-Seq_LNCAP_Human1.28223134
76GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28085757
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.27706345
78JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.27508176
79PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27284222
80SPI1_23127762_ChIP-Seq_K562_Human1.26997050
81STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.26040996
82LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.25039343
83NCOR1_26117541_ChIP-Seq_K562_Human1.24417358
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23849899
85CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23415417
86Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.21509193
87RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20788736
88SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20176474
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19089848
90KDM2B_26808549_Chip-Seq_JURKAT_Human1.17360270
91ELF1_20517297_ChIP-Seq_JURKAT_Human1.15855155
92GATA2_19941826_ChIP-Seq_K562_Human1.15797052
93SPI1_20517297_ChIP-Seq_HL60_Human1.15633249
94KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12875768
95MAF_26560356_Chip-Seq_TH2_Human1.12439315
96FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.11363613
97E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10206302
98TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09073964
99GATA3_26560356_Chip-Seq_TH2_Human1.08860729
100GABP_19822575_ChIP-Seq_HepG2_Human1.06870138
101BCOR_27268052_Chip-Seq_Bcells_Human1.06863653
102PU_27001747_Chip-Seq_BMDM_Mouse1.06486173
103BCL6_27268052_Chip-Seq_Bcells_Human1.06258355
104CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06064758
105NELFA_20434984_ChIP-Seq_ESCs_Mouse1.05961574
106GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.05801020
107TTF2_22483619_ChIP-Seq_HELA_Human1.05639307
108GATA1_19941827_ChIP-Seq_MEL_Mouse1.04060109
109E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03169286
110DCP1A_22483619_ChIP-Seq_HELA_Human1.02274289
111CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01886761
112VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01680705
113KDM5A_27292631_Chip-Seq_BREAST_Human1.01495584
114YY1_21170310_ChIP-Seq_MESCs_Mouse1.01464141
115CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00798759
116RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.00033982
117* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.99697945
118STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.99541195
119SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99172878
120* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98347615
121CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97821391
122PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96865169
123ELK1_19687146_ChIP-ChIP_HELA_Human0.96074742
124CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95681060
125P68_20966046_ChIP-Seq_HELA_Human0.94160794
126ELK3_25401928_ChIP-Seq_HUVEC_Human0.94071888
127MYCN_18555785_ChIP-Seq_MESCs_Mouse0.92700544
128FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92402063
129IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.91971555
130TFEB_21752829_ChIP-Seq_HELA_Human0.91926102
131CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90125528
132MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.89766412
133PU.1_20513432_ChIP-Seq_Bcells_Mouse0.88849692
134E2F1_18555785_ChIP-Seq_MESCs_Mouse0.88084726

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation4.27252581
2MP0002396_abnormal_hematopoietic_system4.17066645
3MP0003436_decreased_susceptibility_to3.17648149
4MP0004808_abnormal_hematopoietic_stem3.03974714
5MP0003693_abnormal_embryo_hatching3.03773458
6MP0005464_abnormal_platelet_physiology2.94125557
7MP0000465_gastrointestinal_hemorrhage2.91437573
8MP0002419_abnormal_innate_immunity2.90771249
9MP0001835_abnormal_antigen_presentation2.71917238
10MP0003183_abnormal_peptide_metabolism2.71678453
11MP0001545_abnormal_hematopoietic_system2.71071333
12MP0005397_hematopoietic_system_phenotyp2.71071333
13MP0009785_altered_susceptibility_to2.47655487
14MP0005025_abnormal_response_to2.45812964
15MP0010094_abnormal_chromosome_stability2.39277806
16MP0003111_abnormal_nucleus_morphology2.31033189
17MP0005174_abnormal_tail_pigmentation2.30960701
18MP0002398_abnormal_bone_marrow2.16947875
19MP0002420_abnormal_adaptive_immunity2.16538939
20MP0002148_abnormal_hypersensitivity_rea2.16172090
21MP0008057_abnormal_DNA_replication2.15843042
22MP0009278_abnormal_bone_marrow2.15386703
23MP0001819_abnormal_immune_cell2.13367468
24MP0003172_abnormal_lysosome_physiology2.07917750
25MP0003828_pulmonary_edema2.07166966
26MP0010307_abnormal_tumor_latency2.06268874
27MP0005000_abnormal_immune_tolerance1.98936229
28MP0002009_preneoplasia1.97985100
29MP0002452_abnormal_antigen_presenting1.92879970
30MP0000716_abnormal_immune_system1.87336481
31MP0006082_CNS_inflammation1.86051005
32MP0001800_abnormal_humoral_immune1.84911060
33MP0002723_abnormal_immune_serum1.84598281
34MP0003300_gastrointestinal_ulcer1.83910227
35MP0003724_increased_susceptibility_to1.83817758
36MP0000490_abnormal_crypts_of1.83172691
37MP0002722_abnormal_immune_system1.82335357
38MP0003077_abnormal_cell_cycle1.81158364
39MP0002166_altered_tumor_susceptibility1.79898755
40MP0002429_abnormal_blood_cell1.76927152
41MP0002405_respiratory_system_inflammati1.73576860
42MP0000685_abnormal_immune_system1.71851096
43MP0008260_abnormal_autophagy1.71343692
44MP0000689_abnormal_spleen_morphology1.70421033
45MP0001853_heart_inflammation1.61482513
46MP0001533_abnormal_skeleton_physiology1.61306515
47MP0004957_abnormal_blastocyst_morpholog1.58269942
48MP0005671_abnormal_response_to1.56276400
49MP0001845_abnormal_inflammatory_respons1.54727644
50MP0000858_altered_metastatic_potential1.51340464
51MP0001851_eye_inflammation1.50090709
52MP0001873_stomach_inflammation1.49820680
53MP0000343_altered_response_to1.49450284
54MP0009333_abnormal_splenocyte_physiolog1.47094637
55MP0010155_abnormal_intestine_physiology1.45494664
56MP0004185_abnormal_adipocyte_glucose1.45040850
57MP0001986_abnormal_taste_sensitivity1.40426042
58MP0003763_abnormal_thymus_physiology1.39066188
59MP0000703_abnormal_thymus_morphology1.35896307
60MP0001790_abnormal_immune_system1.35180626
61MP0005387_immune_system_phenotype1.35180626
62MP0005075_abnormal_melanosome_morpholog1.31901131
63MP0005058_abnormal_lysosome_morphology1.30118601
64MP0002019_abnormal_tumor_incidence1.27712761
65MP0002006_tumorigenesis1.27438165
66MP0002877_abnormal_melanocyte_morpholog1.24749389
67MP0009764_decreased_sensitivity_to1.22175011
68MP0003191_abnormal_cellular_cholesterol1.21789129
69MP0002095_abnormal_skin_pigmentation1.18668162
70MP0008469_abnormal_protein_level1.18120567
71MP0001663_abnormal_digestive_system1.14475467
72MP0003656_abnormal_erythrocyte_physiolo1.13111620
73MP0003866_abnormal_defecation1.10418405
74MP0004883_abnormal_blood_vessel1.08467800
75MP0009840_abnormal_foam_cell1.08128914
76MP0000015_abnormal_ear_pigmentation1.07387055
77MP0004381_abnormal_hair_follicle1.04744308
78MP0000313_abnormal_cell_death1.02088480
79MP0002998_abnormal_bone_remodeling1.02061885
80MP0008007_abnormal_cellular_replicative1.00236649
81MP0005164_abnormal_response_to0.99532980
82MP0003221_abnormal_cardiomyocyte_apopto0.97426570
83MP0003566_abnormal_cell_adhesion0.96846104
84MP0008058_abnormal_DNA_repair0.92843752
85MP0005451_abnormal_body_composition0.92491897
86MP0002089_abnormal_postnatal_growth/wei0.91304035
87MP0010352_gastrointestinal_tract_polyps0.90644568
88MP0004264_abnormal_extraembryonic_tissu0.87899380
89MP0008873_increased_physiological_sensi0.87128644
90MP0009379_abnormal_foot_pigmentation0.83746841
91MP0004130_abnormal_muscle_cell0.82873622
92MP0005666_abnormal_adipose_tissue0.82736599
93MP0005083_abnormal_biliary_tract0.82324847
94MP0000569_abnormal_digit_pigmentation0.80573003
95MP0003075_altered_response_to0.80251896
96MP0009765_abnormal_xenobiotic_induced0.80053238
97MP0004947_skin_inflammation0.79926682
98MP0003786_premature_aging0.79625681
99MP0005076_abnormal_cell_differentiation0.78820017
100MP0000350_abnormal_cell_proliferation0.74203282
101MP0003448_altered_tumor_morphology0.74049992
102MP0005390_skeleton_phenotype0.73149895
103MP0009763_increased_sensitivity_to0.72666735
104MP0006054_spinal_hemorrhage0.72309221
105MP0001730_embryonic_growth_arrest0.72069481
106MP0001764_abnormal_homeostasis0.69565134
107MP0000604_amyloidosis0.66201483
108MP0002970_abnormal_white_adipose0.65922939
109MP0005166_decreased_susceptibility_to0.65486813
110MP0009931_abnormal_skin_appearance0.64385187
111MP0000249_abnormal_blood_vessel0.63317320
112MP0003795_abnormal_bone_structure0.59826059
113MP0005381_digestive/alimentary_phenotyp0.59680089
114MP0002132_abnormal_respiratory_system0.58364568
115MP0002933_joint_inflammation0.57735119
116MP0002080_prenatal_lethality0.57518453
117MP0005621_abnormal_cell_physiology0.57244756
118MP0005023_abnormal_wound_healing0.56982452
119MP0005310_abnormal_salivary_gland0.56858663
120MP0000598_abnormal_liver_morphology0.56709675
121MP0003186_abnormal_redox_activity0.56328218
122MP0005319_abnormal_enzyme/_coenzyme0.56001262
123MP0005376_homeostasis/metabolism_phenot0.52373228
124MP0005535_abnormal_body_temperature0.51758702
125MP0003690_abnormal_glial_cell0.51109913
126MP0008961_abnormal_basal_metabolism0.50809991

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)7.08961969
2Recurrent abscess formation (HP:0002722)5.92200919
3Recurrent bacterial skin infections (HP:0005406)5.44419713
4Thrombocytosis (HP:0001894)5.22040155
5Chronic otitis media (HP:0000389)4.71699493
6Chronic obstructive pulmonary disease (HP:0006510)4.69721882
7Obstructive lung disease (HP:0006536)4.69721882
8Petechiae (HP:0000967)4.42564711
9Recurrent gram-negative bacterial infections (HP:0005420)4.39872055
10Abnormality of cells of the erythroid lineage (HP:0012130)4.17769843
11Abnormal number of erythroid precursors (HP:0012131)4.16171351
12Recurrent fungal infections (HP:0002841)3.99556867
13Recurrent skin infections (HP:0001581)3.69400882
14Papilledema (HP:0001085)3.66907859
15Myositis (HP:0100614)3.65572845
16Meningitis (HP:0001287)3.61216625
17Reticulocytopenia (HP:0001896)3.61043707
18IgM deficiency (HP:0002850)3.53495902
19Hypochromic microcytic anemia (HP:0004840)3.51799053
20Elevated erythrocyte sedimentation rate (HP:0003565)3.51301665
21Prolonged bleeding time (HP:0003010)3.49413860
22Mediastinal lymphadenopathy (HP:0100721)3.47402213
23Cellulitis (HP:0100658)3.39256473
24Amyloidosis (HP:0011034)3.37265533
25Hypochromic anemia (HP:0001931)3.28629795
26Abnormality of the heme biosynthetic pathway (HP:0010472)3.25723441
27Abnormality of macrophages (HP:0004311)3.24719098
28Abnormal platelet function (HP:0011869)3.24682630
29Impaired platelet aggregation (HP:0003540)3.24682630
30Retrobulbar optic neuritis (HP:0100654)3.15679243
31Optic neuritis (HP:0100653)3.15679243
32Epistaxis (HP:0000421)3.13364174
33Chest pain (HP:0100749)3.09220243
34Encephalitis (HP:0002383)3.05635777
35Recurrent cutaneous fungal infections (HP:0011370)3.04126777
36Chronic mucocutaneous candidiasis (HP:0002728)3.04126777
37Aplastic anemia (HP:0001915)3.03243627
38Abnormality of the prostate (HP:0008775)3.03118417
39Gastrointestinal infarctions (HP:0005244)3.00553027
40Recurrent viral infections (HP:0004429)2.95483576
41Agammaglobulinemia (HP:0004432)2.95090203
42Nasal polyposis (HP:0100582)2.90451554
43Long clavicles (HP:0000890)2.85780539
44Poikiloderma (HP:0001029)2.84212719
45Increased cerebral lipofuscin (HP:0011813)2.80228776
46Gingivitis (HP:0000230)2.79690384
47B lymphocytopenia (HP:0010976)2.77911941
48Abnormality of B cell number (HP:0010975)2.77911941
49Cutaneous melanoma (HP:0012056)2.76772379
50Increased neuronal autofluorescent lipopigment (HP:0002074)2.75648319
51Abnormal delayed hypersensitivity skin test (HP:0002963)2.75486823
52Abnormal platelet volume (HP:0011876)2.69855139
53Periodontitis (HP:0000704)2.69015925
54Episodic fever (HP:0001954)2.62232354
55Abnormality of T cell physiology (HP:0011840)2.62068625
56Osteomyelitis (HP:0002754)2.60674552
57Hemoptysis (HP:0002105)2.60010420
58Acute myeloid leukemia (HP:0004808)2.58308259
59Myelodysplasia (HP:0002863)2.56936200
60Acute lymphatic leukemia (HP:0006721)2.56820967
61Granulocytopenia (HP:0001913)2.56136684
62Arterial thrombosis (HP:0004420)2.54071263
63Keratoconjunctivitis sicca (HP:0001097)2.52904258
64Menorrhagia (HP:0000132)2.52655140
65Autoimmune thrombocytopenia (HP:0001973)2.52206991
66Abnormality of the thoracic spine (HP:0100711)2.51376225
67Abnormality of the nasal mucosa (HP:0000433)2.50232571
68Thoracic kyphosis (HP:0002942)2.49272613
69Hepatosplenomegaly (HP:0001433)2.48252123
70Entropion (HP:0000621)2.47658260
71Eosinophilia (HP:0001880)2.46549914
72Reduced antithrombin III activity (HP:0001976)2.45990276
73Hypergammaglobulinemia (HP:0010702)2.45690880
74Increased serum ferritin (HP:0003281)2.45327098
75Spontaneous hematomas (HP:0007420)2.45083409
76Microcytic anemia (HP:0001935)2.44305754
77Urticaria (HP:0001025)2.44072127
78Dysostosis multiplex (HP:0000943)2.42640562
79Vacuolated lymphocytes (HP:0001922)2.41523690
80Abnormality of iron homeostasis (HP:0011031)2.39623936
81Viral hepatitis (HP:0006562)2.39253088
82Gingival bleeding (HP:0000225)2.38632616
83J-shaped sella turcica (HP:0002680)2.35049163
84Leukocytosis (HP:0001974)2.34522494
85Skin rash (HP:0000988)2.33048398
86Colitis (HP:0002583)2.30340508
87Abnormality of DNA repair (HP:0003254)2.27822154
88Abnormality of the fingertips (HP:0001211)2.27229652
89Keratoconjunctivitis (HP:0001096)2.26958834
90Cheilitis (HP:0100825)2.25028735
91Pulmonary embolism (HP:0002204)2.22575645
92Skin ulcer (HP:0200042)2.20526292
93Increased mean platelet volume (HP:0011877)2.16889898
94Bone marrow hypocellularity (HP:0005528)2.14694015
95Recurrent bronchitis (HP:0002837)2.13269431
96Fatigue (HP:0012378)2.13240979
97Pallor (HP:0000980)2.12844765
98Thickened calvaria (HP:0002684)2.10292214
99Polygenic inheritance (HP:0010982)2.10077955
100Increased IgE level (HP:0003212)2.09886886
101Joint hemorrhage (HP:0005261)2.08122738
102Sepsis (HP:0100806)2.05881853
103Vasculitis (HP:0002633)2.05850746
104Gastrointestinal inflammation (HP:0004386)2.05512632
105Neutropenia (HP:0001875)2.05457817
106Amaurosis fugax (HP:0100576)2.03000523
107Interstitial pulmonary disease (HP:0006530)2.02293580
108Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.02248310
109Chromsome breakage (HP:0040012)2.01772200
110Loss of speech (HP:0002371)2.01320593
111Autoimmune hemolytic anemia (HP:0001890)2.00511203
112Thrombophlebitis (HP:0004418)1.99457724
113Inflammation of the large intestine (HP:0002037)1.98885097
114Osteolytic defects of the phalanges of the hand (HP:0009771)1.98215272
115Osteolytic defects of the hand bones (HP:0009699)1.98215272
116Pustule (HP:0200039)1.97542475
117Clubbing of toes (HP:0100760)1.97492903
118High pitched voice (HP:0001620)1.97098171
119Abnormality of the lumbar spine (HP:0100712)1.95578573
120Spondylolisthesis (HP:0003302)1.94929843
121Pulmonary fibrosis (HP:0002206)1.94557200
122Orchitis (HP:0100796)1.94111264
123Pulmonary infiltrates (HP:0002113)1.93583057
124Abnormality of transition element cation homeostasis (HP:0011030)1.91286121
125Slow saccadic eye movements (HP:0000514)1.90436204
126Abnormality of the pleura (HP:0002103)1.89419142
127Type I transferrin isoform profile (HP:0003642)1.88260886
128Abnormality of eosinophils (HP:0001879)1.87409043
129Purpura (HP:0000979)1.86852276
130Gangrene (HP:0100758)1.85532956
131Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.85080058
132Stomatitis (HP:0010280)1.84352232
133Glomerulopathy (HP:0100820)1.83542941
134Abnormality of reticulocytes (HP:0004312)1.83538603
135Abnormality of T cells (HP:0002843)1.83356637
136Abnormality of cells of the lymphoid lineage (HP:0012140)1.82390541
137Thoracolumbar scoliosis (HP:0002944)1.80498324
138Panhypogammaglobulinemia (HP:0003139)1.80020687
139Syringomyelia (HP:0003396)1.79661985
140Spinal cord lesions (HP:0100561)1.79661985

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK33.68869749
2EEF2K3.64383478
3PKN23.54766474
4IRAK43.33230916
5PRPF4B2.99834535
6MAP4K12.94481121
7FES2.72660961
8PIM22.62058326
9BTK2.40232660
10TEC2.27553348
11BLK2.21834733
12STK162.14881907
13KIT2.05553142
14TRIB31.99709413
15GRK61.89172618
16WEE11.87766589
17MAP3K141.76418714
18CDC71.76275887
19RIPK41.76038681
20MAP2K31.75148725
21NEK21.73647701
22CDK121.71633103
23EPHB11.67171159
24ERN11.61498232
25FLT31.56458543
26MAP3K121.52093703
27TESK21.49665396
28LRRK21.49547076
29ZAP701.45611611
30TRPM71.42247919
31RPS6KB21.39885452
32MAP3K131.35811654
33MAPKAPK31.30909123
34SYK1.28349745
35CLK11.25841337
36PAK41.20069500
37SIK21.19533535
38STK101.17030625
39PIM11.16201556
40SCYL21.15292566
41MAP3K31.15163940
42IKBKE1.13258211
43MAP3K61.13155373
44ATR1.11688458
45BUB11.11684462
46IRAK21.10629671
47MAP3K11.04800810
48MAPK41.04549904
49TYK21.03551864
50RAF11.02464995
51VRK10.97643078
52CDK70.96728298
53BMPR20.95671993
54HCK0.95450581
55ITK0.94300828
56RPS6KA20.93377293
57KSR20.92817769
58MARK30.91794660
59EIF2AK30.91772750
60SMG10.89939138
61CDK40.89479780
62MAP3K110.89020455
63RPS6KC10.88844730
64RPS6KL10.88844730
65CSF1R0.88575170
66TXK0.88357872
67TAOK20.87746626
68YES10.87341712
69FGR0.86174806
70IKBKB0.86124741
71RPS6KA60.84764400
72LYN0.84170645
73MARK20.82961840
74ALK0.82948725
75MATK0.80280470
76PDK10.79121196
77IRAK10.78408823
78TESK10.77953141
79PTK60.77879893
80BRSK20.77561640
81IRAK30.76990191
82TBK10.76708064
83CSK0.76476378
84MAPK120.76333577
85TNK20.75104888
86MAP3K80.74831477
87DAPK10.74636522
88PDPK10.74479597
89TSSK60.72668995
90TTN0.71848845
91MKNK10.71204360
92LCK0.69308831
93SRPK10.69290426
94CDK60.68491074
95RET0.66840520
96PASK0.66493194
97BRD40.66061258
98MAP2K40.64787772
99STK40.64743296
100MAPK70.63975074
101ILK0.63951600
102JAK20.61611405
103JAK10.61552859
104PIK3CG0.60619540
105PRKCQ0.57234541
106MAPKAPK50.56305106
107KDR0.53257681
108MAP3K70.52430129
109ICK0.52137887
110MAP2K20.50920534
111MAPK110.50462235
112NME20.49400040
113MAPKAPK20.47693421
114PRKD20.47332991
115AURKB0.46428426
116CDK30.43810051
117CDK190.43084806
118MAP2K60.42511968
119MAP3K50.42338436
120SIK30.42175411
121MOS0.40948999
122STK110.40407552
123TGFBR20.37641948
124MKNK20.37533003
125FYN0.36661937
126HIPK20.36307372
127RPS6KB10.35652498
128TAOK10.35650735
129RPS6KA40.35119212
130MAPK30.34834407
131PLK10.34103236
132PAK20.33981550
133CHEK10.33750088
134MAP3K20.33255998
135RPS6KA10.32975314
136CDK80.30786371
137JAK30.30753660
138DYRK30.30298273
139PAK10.30277709
140EIF2AK10.28812123
141CSNK2A20.28694997
142ERBB30.27828189

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.53137280
2DNA replication_Homo sapiens_hsa030304.38097888
3Asthma_Homo sapiens_hsa053103.01709179
4Ribosome_Homo sapiens_hsa030102.77430306
5Mismatch repair_Homo sapiens_hsa034302.50467041
6Leishmaniasis_Homo sapiens_hsa051402.41777199
7Pentose phosphate pathway_Homo sapiens_hsa000302.35756580
8Base excision repair_Homo sapiens_hsa034102.35340380
9Homologous recombination_Homo sapiens_hsa034402.17555035
10Renin-angiotensin system_Homo sapiens_hsa046142.01572048
11Other glycan degradation_Homo sapiens_hsa005112.01381950
12Spliceosome_Homo sapiens_hsa030401.77978711
13N-Glycan biosynthesis_Homo sapiens_hsa005101.73507211
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.72284681
15Malaria_Homo sapiens_hsa051441.71355550
16Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.69898042
17Cell cycle_Homo sapiens_hsa041101.57359389
18Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.53890716
19T cell receptor signaling pathway_Homo sapiens_hsa046601.50391910
20Osteoclast differentiation_Homo sapiens_hsa043801.41142607
21Glycosaminoglycan degradation_Homo sapiens_hsa005311.39478631
22B cell receptor signaling pathway_Homo sapiens_hsa046621.37634041
23Graft-versus-host disease_Homo sapiens_hsa053321.37017482
24Nucleotide excision repair_Homo sapiens_hsa034201.34980509
25Allograft rejection_Homo sapiens_hsa053301.32855026
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.31742493
27NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27940424
28Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.27611318
29Antigen processing and presentation_Homo sapiens_hsa046121.27237629
30Hematopoietic cell lineage_Homo sapiens_hsa046401.26738694
31One carbon pool by folate_Homo sapiens_hsa006701.26464641
32Acute myeloid leukemia_Homo sapiens_hsa052211.25135904
33African trypanosomiasis_Homo sapiens_hsa051431.24985307
34Galactose metabolism_Homo sapiens_hsa000521.24241718
35Fanconi anemia pathway_Homo sapiens_hsa034601.23689280
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.22992605
37Autoimmune thyroid disease_Homo sapiens_hsa053201.19491058
38Non-homologous end-joining_Homo sapiens_hsa034501.18480345
39Herpes simplex infection_Homo sapiens_hsa051681.18388513
40Legionellosis_Homo sapiens_hsa051341.17632900
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.17577101
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.17086703
43Protein export_Homo sapiens_hsa030601.14706531
44Leukocyte transendothelial migration_Homo sapiens_hsa046701.12412272
45TNF signaling pathway_Homo sapiens_hsa046681.11547726
46Primary immunodeficiency_Homo sapiens_hsa053401.10645101
47Platelet activation_Homo sapiens_hsa046111.07142530
48RNA transport_Homo sapiens_hsa030131.04586989
49Tuberculosis_Homo sapiens_hsa051521.03789590
50Apoptosis_Homo sapiens_hsa042101.02709761
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.01826300
52Pyrimidine metabolism_Homo sapiens_hsa002401.01602795
53Chronic myeloid leukemia_Homo sapiens_hsa052201.00550696
54Shigellosis_Homo sapiens_hsa051310.96974577
55Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96809199
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.96530235
57Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96372136
58Non-small cell lung cancer_Homo sapiens_hsa052230.94734055
59Carbohydrate digestion and absorption_Homo sapiens_hsa049730.94106293
60Measles_Homo sapiens_hsa051620.92996451
61Pertussis_Homo sapiens_hsa051330.91928710
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.89936007
63Hepatitis B_Homo sapiens_hsa051610.89803401
64Amoebiasis_Homo sapiens_hsa051460.88104355
65Phagosome_Homo sapiens_hsa041450.87371053
66Fructose and mannose metabolism_Homo sapiens_hsa000510.87123425
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86813461
68Type I diabetes mellitus_Homo sapiens_hsa049400.86597886
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85906993
70Hepatitis C_Homo sapiens_hsa051600.85090093
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.85053052
72Choline metabolism in cancer_Homo sapiens_hsa052310.84269997
73p53 signaling pathway_Homo sapiens_hsa041150.84169372
74Starch and sucrose metabolism_Homo sapiens_hsa005000.83528168
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.83047530
76Toxoplasmosis_Homo sapiens_hsa051450.81990051
77Prolactin signaling pathway_Homo sapiens_hsa049170.81422120
78Renal cell carcinoma_Homo sapiens_hsa052110.80696864
79mTOR signaling pathway_Homo sapiens_hsa041500.80581025
80Jak-STAT signaling pathway_Homo sapiens_hsa046300.79813162
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.76858924
82Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76616257
83Viral myocarditis_Homo sapiens_hsa054160.76117631
84Toll-like receptor signaling pathway_Homo sapiens_hsa046200.75974129
85Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75774350
86Chemokine signaling pathway_Homo sapiens_hsa040620.75612732
87Glycerophospholipid metabolism_Homo sapiens_hsa005640.74617684
88NF-kappa B signaling pathway_Homo sapiens_hsa040640.74209112
89Thyroid cancer_Homo sapiens_hsa052160.74069425
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.73855357
91Colorectal cancer_Homo sapiens_hsa052100.73671940
92GnRH signaling pathway_Homo sapiens_hsa049120.72890510
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72777226
94RNA degradation_Homo sapiens_hsa030180.71848255
95Epstein-Barr virus infection_Homo sapiens_hsa051690.71027768
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.70043006
97Biosynthesis of amino acids_Homo sapiens_hsa012300.69857502
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.69590448
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.69522297
100Influenza A_Homo sapiens_hsa051640.69457167
101ABC transporters_Homo sapiens_hsa020100.69373902
102Lysosome_Homo sapiens_hsa041420.69291495
103Notch signaling pathway_Homo sapiens_hsa043300.68130922
104Endometrial cancer_Homo sapiens_hsa052130.66407945
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.65635061
106Inositol phosphate metabolism_Homo sapiens_hsa005620.65137623
107Viral carcinogenesis_Homo sapiens_hsa052030.64962238
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64022291
109FoxO signaling pathway_Homo sapiens_hsa040680.63868835
110Salmonella infection_Homo sapiens_hsa051320.61950740
111Glutathione metabolism_Homo sapiens_hsa004800.61657062
112HIF-1 signaling pathway_Homo sapiens_hsa040660.60952377
113Type II diabetes mellitus_Homo sapiens_hsa049300.60053792
114Small cell lung cancer_Homo sapiens_hsa052220.60042257
115Staphylococcus aureus infection_Homo sapiens_hsa051500.59607675
116Sulfur relay system_Homo sapiens_hsa041220.59184455
117Dorso-ventral axis formation_Homo sapiens_hsa043200.59154332
118Rheumatoid arthritis_Homo sapiens_hsa053230.57813728
119Carbon metabolism_Homo sapiens_hsa012000.57761801
120SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57295672
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57157732
122VEGF signaling pathway_Homo sapiens_hsa043700.56582173
123Insulin resistance_Homo sapiens_hsa049310.56381556
124Pancreatic cancer_Homo sapiens_hsa052120.55517909
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54583139
126mRNA surveillance pathway_Homo sapiens_hsa030150.54373191
127Cyanoamino acid metabolism_Homo sapiens_hsa004600.51229919
128Proteasome_Homo sapiens_hsa030500.51048172
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50731014
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48980456
131Regulation of autophagy_Homo sapiens_hsa041400.45816450
132Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44908327
133ErbB signaling pathway_Homo sapiens_hsa040120.43555228
134HTLV-I infection_Homo sapiens_hsa051660.42353095
135Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42264380
136Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41212975
137Systemic lupus erythematosus_Homo sapiens_hsa053220.39061807
138Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38767594
139Drug metabolism - other enzymes_Homo sapiens_hsa009830.38290804
140RNA polymerase_Homo sapiens_hsa030200.38266428

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